Anastasia Stefania Alexopoulos
Assistant Professor of Medicine
Current Research Interests
Diabetes
Nonalcoholic fatty liver disease
Health Services Research
Nonalcoholic fatty liver disease
Health Services Research
Current Appointments & Affiliations
- Assistant Professor of Medicine, Medicine, Endocrinology, Metabolism, and Nutrition, Medicine 2021
Contact Information
- Background
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Education, Training, & Certifications
- Fellowship, Endocrinology, Brigham and Women's Hospital 2017 - 2018
- Residency, Internal Medicine, Emory University School of Medicine 2013 - 2016
- M.B.B.S., Imperial College London (United Kingdom) 2012
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Previous Appointments & Affiliations
- Assistant Professor of Medicine, Medicine, Endocrinology, Metabolism, and Nutrition, Medicine 2020
- Recognition
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In the News
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MAY 18, 2021 Duke Health News
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- Expertise
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Subject Headings
- Research
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Selected Grants
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Fellowships, Supported Research, & Other Grants
- Internal Pilot Grant awarded by Center of Innovation to Accelerate Discovery and Practice Transformation (ADAPT), Durham VA Medical Center 2020 - 2021
- Project grant awarded by Endocrine Fellows Foundation 2019 - 2020
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Alexopoulos, Anastasia-Stefania, Matthew J. Crowley, and Anna R. Kahkoska. “Diabetes Medication Changes in Older Adults With Type 2 Diabetes: Insights Into Physician Factors and Questions Ahead.” Diabetes Care 46, no. 6 (June 1, 2023): 1137–39. https://doi.org/10.2337/dci23-0017.Full Text Link to Item
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Zupa, Margaret F., Anastasia-Stefania Alexopoulos, Lucy Esteve, and Ann-Marie Rosland. “Specialist Perspectives on Delivering High-Quality Telemedicine for Diabetes: A Mixed Methods Survey Study.” J Endocr Soc 7, no. 5 (March 6, 2023): bvad039. https://doi.org/10.1210/jendso/bvad039.Full Text Open Access Copy Link to Item
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Alexopoulos, Anastasia-Stefania, Diana Soliman, Allison A. Lewinski, Elizabeth Strawbridge, Karen Steinhauser, David Edelman, and Matthew J. Crowley. “Simplifying therapy to assure glycemic control and engagement (STAGE) in poorly-controlled diabetes: A pilot study.” J Diabetes Complications 37, no. 1 (January 2023): 108364. https://doi.org/10.1016/j.jdiacomp.2022.108364.Full Text Link to Item
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Lewinski, Allison A., Conor Walsh, Sharron Rushton, Diana Soliman, Scott M. Carlson, Matthew W. Luedke, David J. Halpern, et al. “Telehealth for the Longitudinal Management of Chronic Conditions: Systematic Review.” J Med Internet Res 24, no. 8 (August 26, 2022): e37100. https://doi.org/10.2196/37100.Full Text Link to Item
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Sagalla, Nicole, William S. Yancy, David Edelman, Amy S. Jeffreys, Cynthia J. Coffman, Corrine I. Voils, Anastasia-Stefania Alexopoulos, Matthew L. Maciejewski, Moahad Dar, and Matthew J. Crowley. “Factors associated with non-adherence to insulin and non-insulin medications in patients with poorly controlled diabetes.” Chronic Illn 18, no. 2 (June 2022): 398–409. https://doi.org/10.1177/1742395320968627.Full Text Link to Item
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Alexopoulos, Anastasia-Stefania, Ryan Duffy, Elizabeth A. Kobe, Jashalynn German, Cynthia A. Moylan, Diana Soliman, Amy S. Jeffreys, Cynthia J. Coffman, and Matthew J. Crowley. “Underrecognition of Nonalcoholic Fatty Liver Disease in Poorly Controlled Diabetes: A Call to Action in Diabetes Care.” J Endocr Soc 5, no. 12 (December 1, 2021): bvab155. https://doi.org/10.1210/jendso/bvab155.Full Text Link to Item
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Alexopoulos, Anastasia-Stefania, William S. Yancy, David Edelman, Cynthia J. Coffman, Amy S. Jeffreys, Matthew L. Maciejewski, Corrine I. Voils, et al. “Clinical associations of an updated medication effect score for measuring diabetes treatment intensity.” Chronic Illn 17, no. 4 (December 2021): 451–62. https://doi.org/10.1177/1742395319884096.Full Text Link to Item
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Alexopoulos, Anastasia-Stefania, Anna R. Kahkoska, Virginia Pate, Marie C. Bradley, Joshua Niznik, Carolyn Thorpe, Til Stürmer, and John Buse. “Deintensification of Treatment With Sulfonylurea and Insulin After Severe Hypoglycemia Among Older Adults With Diabetes.” Jama Netw Open 4, no. 11 (November 1, 2021): e2132215. https://doi.org/10.1001/jamanetworkopen.2021.32215.Full Text Link to Item
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Alexopoulos, Anastasia-Stefania, Matthew J. Crowley, Ying Wang, Cynthia A. Moylan, Cynthia D. Guy, Ricardo Henao, Dawn L. Piercy, et al. “Glycemic Control Predicts Severity of Hepatocyte Ballooning and Hepatic Fibrosis in Nonalcoholic Fatty Liver Disease.” Hepatology 74, no. 3 (September 2021): 1220–33. https://doi.org/10.1002/hep.31806.Full Text Open Access Copy Link to Item
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Alexopoulos, Anastasia-Stefania, Andreas Andersen, Anders Meller Donatsky, Amoolya Gowda, and John B. Buse. “Duration of type 2 diabetes does not appear to moderate hypoglycaemia rate with insulin degludec versus insulin glargine U100.” Diabetes Obes Metab 23, no. 8 (August 2021): 1983–88. https://doi.org/10.1111/dom.14397.Full Text Link to Item
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Kobe, Elizabeth A., Clarissa J. Diamantidis, Hayden B. Bosworth, Clemontina A. Davenport, Megan Oakes, Anastasia-Stefania Alexopoulos, Jane Pendergast, Uptal D. Patel, and Matthew J. Crowley. “Racial Differences in the Effectiveness of a Multifactorial Telehealth Intervention to Slow Diabetic Kidney Disease.” Med Care 58, no. 11 (November 2020): 968–73. https://doi.org/10.1097/MLR.0000000000001387.Full Text Link to Item
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Yang, Jeff Y., Andrew M. Moon, Hannah Kim, Virginia Pate, A Sidney Barritt, Matthew J. Crowley, John B. Buse, Til Stürmer, and Anastasia-Stefania Alexopoulos. “Newer second-line glucose-lowering drugs versus thiazolidinediones on cirrhosis risk among older US adult patients with type 2 diabetes.” J Diabetes Complications 34, no. 11 (November 2020): 107706. https://doi.org/10.1016/j.jdiacomp.2020.107706.Full Text Link to Item
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Crowley, Matthew J., Darren K. McGuire, Anastasia-Stefania Alexopoulos, Thomas Jon Jensen, Søren Rasmussen, Hans A. Saevereid, Subodh Verma, and John B. Buse. “Effects of Liraglutide on Cardiovascular Outcomes in Type 2 Diabetes Patients With and Without Baseline Metformin Use: Post Hoc Analyses of the LEADER Trial.” Diabetes Care 43, no. 9 (September 2020): e108–10. https://doi.org/10.2337/dc20-0437.Full Text Link to Item
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Lunyera, Joseph, Dinushika Mohottige, Anastasia-Stefania Alexopoulos, Hilary Campbell, C Blake Cameron, Nicole Sagalla, Timothy J. Amrhein, et al. “Risk for Nephrogenic Systemic Fibrosis After Exposure to Newer Gadolinium Agents: A Systematic Review.” Ann Intern Med 173, no. 2 (July 21, 2020): 110–19. https://doi.org/10.7326/M20-0299.Full Text Link to Item
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Li, Dandan, Jocelyn Anne Silvester, Matthew J. Crowley, Jeff Y. Yang, Anastasia-Stefania Alexopoulos, Yang Xu, Siyan Zhan, and Tiansheng Wang. “Assessing the association between dipeptidyl peptidase-4 inhibitors use and celiac disease through drug adverse event reporting.” Ther Adv Chronic Dis 11 (2020): 2040622320904301. https://doi.org/10.1177/2040622320904301.Full Text Link to Item
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Wolf, Rachel A., J Sonya Haw, Sudeshna Paul, Melissa Spezia Faulkner, EunSeok Cha, M. K. Findley, Farah Khan, et al. “Hospital admissions for hyperglycemic emergencies in young adults at an inner-city hospital.” Diabetes Res Clin Pract 157 (November 2019): 107869. https://doi.org/10.1016/j.diabres.2019.107869.Full Text Link to Item
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Alexopoulos, A. S., R. Blair, and A. L. Peters. “Management of Preexisting Diabetes in Pregnancy: A Review.” Obstetrical and Gynecological Survey 74, no. 10 (October 1, 2019): 574–76. https://doi.org/10.1097/OGX.0000000000000726.Full Text
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Alexopoulos, Anastasia-Stefania, and John B. Buse. “Initial injectable therapy in type 2 diabetes: Key considerations when choosing between glucagon-like peptide 1 receptor agonists and insulin.” Metabolism 98 (September 2019): 104–11. https://doi.org/10.1016/j.metabol.2019.06.012.Full Text Link to Item
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Alexopoulos, Anastasia-Stefania, Rachel Blair, and Anne L. Peters. “Management of Preexisting Diabetes in Pregnancy: A Review.” Jama 321, no. 18 (May 14, 2019): 1811–19. https://doi.org/10.1001/jama.2019.4981.Full Text Link to Item
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Alexopoulos, Anastasia-Stefania, Ali Qamar, Kathryn Hutchins, Matthew J. Crowley, Bryan C. Batch, and John R. Guyton. “Triglycerides: Emerging Targets in Diabetes Care? Review of Moderate Hypertriglyceridemia in Diabetes.” Curr Diab Rep 19, no. 4 (February 26, 2019): 13. https://doi.org/10.1007/s11892-019-1136-3.Full Text Link to Item
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Alexopoulos, Anastasia-Stefania, George L. Jackson, David Edelman, Valerie A. Smith, Theodore S. Z. Berkowitz, Sandra L. Woolson, Hayden B. Bosworth, and Matthew J. Crowley. “Clinical factors associated with persistently poor diabetes control in the Veterans Health Administration: A nationwide cohort study.” Plos One 14, no. 3 (2019): e0214679. https://doi.org/10.1371/journal.pone.0214679.Full Text Link to Item
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Alexopoulos, A. S., M. Fayfman, L. Zhao, J. Weaver, L. Buehler, D. Smiley, F. J. Pasquel, P. Vellanki, J. Sonya Haw, and G. E. Umpierrez. “Impact of obesity on hospital complications and mortality in hospitalized patients with hyperglycemia and diabetes.” Bmj Open Diabetes Research and Care 4, no. 1 (July 1, 2016). https://doi.org/10.1136/bmjdrc-2016-000200.Full Text
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Fayfman, Maya, Priyathama Vellanki, Anastasia-Stefania Alexopoulos, Lauren Buehler, Liping Zhao, Dawn Smiley, Sonya Haw, Jeff Weaver, Francisco J. Pasquel, and Guillermo E. Umpierrez. “Report on Racial Disparities in Hospitalized Patients with Hyperglycemia and Diabetes.” J Clin Endocrinol Metab 101, no. 3 (March 2016): 1144–50. https://doi.org/10.1210/jc.2015-3220.Full Text Link to Item
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Baptiste, G. G., A. S. Alexopoulos, T. Masud, and J. M. Bonsall. “Systemic Levamisole-Induced Vasculitis in a Cocaine User without Cutaneous Findings: A Consideration in Diagnosis.” Case Reports in Medicine 2015 (January 1, 2015). https://doi.org/10.1155/2015/547023.Full Text
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Buehler, Lauren, Maya Fayfman, Anastasia-Stefania Alexopoulos, Liping Zhao, Farnoosh Farrokhi, Jeff Weaver, Dawn Smiley-Byrd, Francisco J. Pasquel, Priyathama Vellanki, and Guillermo E. Umpierrez. “The impact of hyperglycemia and obesity on hospitalization costs and clinical outcome in general surgery patients.” J Diabetes Complications 29, no. 8 (2015): 1177–82. https://doi.org/10.1016/j.jdiacomp.2015.07.027.Full Text Link to Item
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Shariq, Omair, Anastasia-Stefania Alexopoulos, Fathima Razik, Jane Currie, and Nina Salooja. “Teaching skills training for medical students.” Clin Teach 10, no. 3 (June 2013): 146–50. https://doi.org/10.1111/j.1743-498X.2012.00628.x.Full Text Link to Item
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Alexopoulos, A. -. S., and O. Shariq. “Assessing stress in surgery: using validated tools to improve patient safety.” Ir J Med Sci 180, no. 2 (June 2011): 617. https://doi.org/10.1007/s11845-010-0642-8.Full Text Link to Item
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Alexopoulos, A. -. S. “Junior tutor programme--benefits and risks.” Ir J Med Sci 180, no. 1 (March 2011): 305. https://doi.org/10.1007/s11845-010-0600-5.Full Text Link to Item
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Shariq, O., A. S. Alexopoulos, and F. Razik. “The need for more teaching-skills training for medical students.” Academic Medicine 86, no. 4 (January 1, 2011): 407–8. https://doi.org/10.1097/ACM.0b013e31820dcba3.Full Text
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Conference Papers
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Lewinski, Allison A., Conor Walsh, Sharron Rushton, Diana Soliman, Scott Carlson, Matthew W. Luedke, David Halpern, et al. “VIRTUAL CARE FOR THE LONGITUDINAL MANAGEMENT OF CHRONIC CONDITIONS: A SYSTEMATIC REVIEW.” In Annals of Behavioral Medicine, 56:S674–S674, 2022.Link to Item
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Yang, Jeff Y., Anastasia Alexopoulos, Andrew M. Moon, Hannah Kim, Virginia Pate, A Sidney Barritt, Til Sturmer, and John B. Buse. “Newer second-line glucose-lowering drugs versus thiazolidinediones and cirrhosis risk in type 2 diabetes.” In Pharmacoepidemiology and Drug Safety, 29:606–606, 2020.Link to Item
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Razik, Fathima, Anastasia-Stefania Alexopoulos, Bassel El-Osta, Michelle J. Connolly, Ashley Brown, Soueid Hassan, and Kasetti Ravikumar. “Time to internal fixation of femoral neck fractures in patients under sixty years--does this matter in the development of osteonecrosis of femoral head?” In Int Orthop, 36:2127–32, 2012. https://doi.org/10.1007/s00264-012-1619-1.Full Text Link to Item
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Shariq, Omair, Aaron Odedra, Anastasia-Stefania Alexopoulos, Stuart Gould, and Ramawad Soobrah. “Synchronous occurrence of gastrointestinal stromal tumour and ovarian neoplasm in a patient presenting with acute cholecystitis.” In J Gastrointest Cancer, 43:113–16, 2012. https://doi.org/10.1007/s12029-011-9265-1.Full Text Link to Item
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