Andrea Sitlinger
Assistant Professor of Medicine
Current Research Interests
My research focuses specifically on improving clinical outcomes for lymphoma patients with interventions in exercise, survivorship, and financial toxicity. I also participate in a number of treatment related clinical trials to help patients access the latest available treatments and continue to improve our treatment options for these patients.
I thoroughly enjoy each opportunity for patient care, and my patients are truly the driver for my research questions and interests. Overall, I hope to 1) provide each patient with a personalized experience that optimizes his or her own care and 2) advance the field of survivorship and chronic cancer management to inform the overall care of these patients and ultimately improve their outcomes.
Current Appointments & Affiliations
- Assistant Professor of Medicine, Medicine, Hematologic Malignancies and Cellular Therapy, Medicine 2022
- Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 2019
Contact Information
- Background
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Education, Training, & Certifications
- Senior Fellow, Hematology / Oncology, Duke Universitymedical Center, Duke University 2016 - 2019
- Internal Medicine Residency, Duke University Medical Center, Duke University 2013 - 2016
- M.D., University of Cincinnati, College of Medicine 2013
- B.S., Miami University, Hamilton 2006
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Medical Licensure
- 2019-01277. North Carolina. 2019
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Previous Appointments & Affiliations
- Medical Instructor in the Department of Medicine, Medicine, Hematologic Malignancies and Cellular Therapy, Medicine 2019 - 2021
- Expertise
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Subject Headings
- Research
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Selected Grants
- Loxo: III Trial of Fixed Pirtobrutinib + Vene and Rituximab vs Vene + Rituximab in CLL/SLL awarded by Loxo Oncology, Inc. 2022 - 2027
- US Post-Marketing Retrospective Observational Safety Study of Moxetumomab Pasudotox-tdfk (LUMOXITITM awarded by Innate Pharma 2021 - 2026
- DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED, PROSPECTIVE PHASE III STUDY EVALUATING EFFICACY AND SAFETY OF PANZYGA IN PRIMARY INFECTION PROPHYLAXIS IN PATIENTS WITH CHRONIC LYMPHOCYTIC LEUKEMIA ("PRO-SID" study) awarded by Octapharma AG 2020 - 2025
- A Multicenter, Open-Label, Single-Arm, Phase 2 Study of ME-401 in Subjects with Follicular Lymphoma After Failure of Two or More Prior Systemic Therapies awarded by MEI Pharma, Inc. 2020 - 2025
- Exercise training to promote improved immune resilience in adults with chronic lymphocytic leukemia - a randomized control trial awarded by American Society of Hematology 2020 - 2021
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External Relationships
- BeiGene
- OncLive
- Remedy Health Media (Patient Power)
- TG Therapeutics, IC, New York NY
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Hamparsumian, Anahid, Colette Whitney, Dan Blalock, Andrea Sitlinger, Mohammad Shahsahebi, Kevin Oeffinger, Leah Zullig, and Danielle Brander. “CLL-517 Hypertension as an Adverse Event of Ibrutinib: Does Age Matter?” Clin Lymphoma Myeloma Leuk 22 Suppl 2 (October 2022): S282. https://doi.org/10.1016/S2152-2650(22)01353-2.Full Text Link to Item
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Artese, Ashley L., Andrea Sitlinger, Grace MacDonald, Michael A. Deal, Erik D. Hanson, Carl F. Pieper, J Brice Weinberg, Danielle M. Brander, and David B. Bartlett. “Effects of high-intensity interval training on health-related quality of life in chronic lymphocytic leukemia: A pilot study.” J Geriatr Oncol, September 9, 2022. https://doi.org/10.1016/j.jgo.2022.09.002.Full Text Link to Item
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Saber, Ibrahim, Alys Adamski, Maragatha Kuchibhatla, Karon Abe, Michele Beckman, Nimia Reyes, Ryan Schulteis, et al. “Racial differences in venous thromboembolism: A surveillance program in Durham County, North Carolina.” Res Pract Thromb Haemost 6, no. 5 (July 2022): e12769. https://doi.org/10.1002/rth2.12769.Full Text Link to Item
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Zullig, Leah L., Anthony D. Sung, Michel G. Khouri, Shelley Jazowski, Nishant P. Shah, Andrea Sitlinger, Dan V. Blalock, et al. “Cardiometabolic Comorbidities in Cancer Survivors: JACC: CardioOncology State-of-the-Art Review.” Jacc Cardiooncol 4, no. 2 (June 2022): 149–65. https://doi.org/10.1016/j.jaccao.2022.03.005.Full Text Open Access Copy Link to Item
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Sitlinger, Andrea, Michael A. Deal, Erwin Garcia, Margery Connelly, Dana Thompson, Tiffany Stewart, Grace Macdonald, et al. “Associations of clinical and circulating metabolic biomarkers with low physical fitness and function in adults with chronic lymphocytic leukemia.” Front Oncol 12 (2022): 933619. https://doi.org/10.3389/fonc.2022.933619.Full Text Link to Item
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MacDonald, Grace, Andrea Sitlinger, Michael A. Deal, Erik D. Hanson, Stephanie Ferraro, Carl F. Pieper, J Brice Weinberg, Danielle M. Brander, and David B. Bartlett. “A pilot study of high-intensity interval training in older adults with treatment naïve chronic lymphocytic leukemia.” Sci Rep 11, no. 1 (November 30, 2021): 23137. https://doi.org/10.1038/s41598-021-02352-6.Full Text Link to Item
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Gordon, Max J., Andy Kaempf, Andrea Sitlinger, Geoffrey Shouse, Matthew Mei, Danielle M. Brander, Tareq Salous, et al. “The Chronic Lymphocytic Leukemia Comorbidity Index (CLL-CI): A Three-Factor Comorbidity Model.” Clin Cancer Res 27, no. 17 (September 1, 2021): 4814–24. https://doi.org/10.1158/1078-0432.CCR-20-3993.Full Text Link to Item
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Mato, Anthony R., Nilanjan Ghosh, Stephen J. Schuster, Nicole Lamanna, John M. Pagel, Ian W. Flinn, Jacqueline C. Barrientos, et al. “Phase 2 study of the safety and efficacy of umbralisib in patients with CLL who are intolerant to BTK or PI3Kδ inhibitor therapy.” Blood 137, no. 20 (May 20, 2021): 2817–26. https://doi.org/10.1182/blood.2020007376.Full Text Link to Item
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Sitlinger, Andrea, Michael A. Deal, Erwin Garcia, Dana K. Thompson, Tiffany Stewart, Grace A. MacDonald, Nicolas Devos, et al. “Physiological Fitness and the Pathophysiology of Chronic Lymphocytic Leukemia (CLL).” Cells 10, no. 5 (May 11, 2021). https://doi.org/10.3390/cells10051165.Full Text Link to Item
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Eyre, Toby A., Nicole Lamanna, Lindsey E. Roeker, Chaitra S. Ujjani, Brian T. Hill, Paul M. Barr, Erick Lansigan, et al. “Comparative analysis of targeted novel therapies in relapsed, refractory chronic lymphocytic leukaemia.” Haematologica 106, no. 1 (January 1, 2021): 284–87. https://doi.org/10.3324/haematol.2019.241539.Full Text Link to Item
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Roeker, Lindsey E., Peter Dreger, Jennifer R. Brown, Oscar B. Lahoud, Toby A. Eyre, Danielle M. Brander, Alan Skarbnik, et al. “Allogeneic stem cell transplantation for chronic lymphocytic leukemia in the era of novel agents.” Blood Adv 4, no. 16 (August 25, 2020): 3977–89. https://doi.org/10.1182/bloodadvances.2020001956.Full Text Link to Item
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Mato, Anthony R., Lindsey E. Roeker, Ryan Jacobs, Brian T. Hill, Nicole Lamanna, Danielle Brander, Mazyar Shadman, et al. “Assessment of the Efficacy of Therapies Following Venetoclax Discontinuation in CLL Reveals BTK Inhibition as an Effective Strategy.” Clin Cancer Res 26, no. 14 (July 15, 2020): 3589–96. https://doi.org/10.1158/1078-0432.CCR-19-3815.Full Text Link to Item
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Sitlinger, Andrea, Danielle M. Brander, and David B. Bartlett. “Impact of exercise on the immune system and outcomes in hematologic malignancies.” Blood Adv 4, no. 8 (April 28, 2020): 1801–11. https://doi.org/10.1182/bloodadvances.2019001317.Full Text Link to Item
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Gordon, Max J., Andrea Sitlinger, Tareq Salous, Hamood Alqahtani, Michael Churnetski, Xavier Rivera, Paul Wisniewski, et al. “A simplified prognostic index for chronic lymphocytic leukemia treated with ibrutinib: Results from a multicenter retrospective cohort study.” Leuk Res 89 (February 2020): 106302. https://doi.org/10.1016/j.leukres.2020.106302.Full Text Link to Item
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Roeker, Lindsey E., Christopher P. Fox, Toby A. Eyre, Danielle M. Brander, John N. Allan, Stephen J. Schuster, Chadi Nabhan, et al. “Tumor Lysis, Adverse Events, and Dose Adjustments in 297 Venetoclax-Treated CLL Patients in Routine Clinical Practice.” Clin Cancer Res 25, no. 14 (July 15, 2019): 4264–70. https://doi.org/10.1158/1078-0432.CCR-19-0361.Full Text Link to Item
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Mato, Anthony R., Lindsey E. Roeker, Toby A. Eyre, Chadi Nabhan, Nicole Lamanna, Brian T. Hill, Danielle M. Brander, et al. “A retrospective comparison of venetoclax alone or in combination with an anti-CD20 monoclonal antibody in R/R CLL.” Blood Adv 3, no. 10 (May 28, 2019): 1568–73. https://doi.org/10.1182/bloodadvances.2019000180.Full Text Link to Item
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Ortel, Thomas L., Katie Arnold, Michele Beckman, Audrey Brown, Nimia Reyes, Ibrahim Saber, Ryan Schulteis, Bhavana Pendurthi Singh, Andrea Sitlinger, and Elizabeth H. Thames. “Design and Implementation of a Comprehensive Surveillance System for Venous Thromboembolism in a Defined Region Using Electronic and Manual Approaches.” Appl Clin Inform 10, no. 3 (May 2019): 552–62. https://doi.org/10.1055/s-0039-1693711.Full Text Link to Item
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Sitlinger, Andrea, Rebecca A. Shelby, Alyssa N. Van Denburg, Heidi White, Sarah N. Edmond, Paul K. Marcom, Hayden B. Bosworth, Francis J. Keefe, and Gretchen G. Kimmick. “Higher symptom burden is associated with lower function in women taking adjuvant endocrine therapy for breast cancer.” J Geriatr Oncol 10, no. 2 (March 2019): 317–21. https://doi.org/10.1016/j.jgo.2018.11.008.Full Text Link to Item
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Sitlinger, Andrea, and Syed Yousuf Zafar. “Health-Related Quality of Life: The Impact on Morbidity and Mortality.” Surg Oncol Clin N Am 27, no. 4 (October 2018): 675–84. https://doi.org/10.1016/j.soc.2018.05.008.Full Text Link to Item
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Mato, Anthony R., Meghan Thompson, John N. Allan, Danielle M. Brander, John M. Pagel, Chaitra S. Ujjani, Brian T. Hill, et al. “Real-world outcomes and management strategies for venetoclax-treated chronic lymphocytic leukemia patients in the United States.” Haematologica 103, no. 9 (September 2018): 1511–17. https://doi.org/10.3324/haematol.2018.193615.Full Text Link to Item
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Sitlinger, Andrea Phillips, and S Yousuf Zafar. “With Colorectal Cancer Treatment, Physical Toxicity Is Not the Only Concern.” Dis Colon Rectum 61, no. 1 (January 2018): 4–5. https://doi.org/10.1097/DCR.0000000000000922.Full Text Link to Item
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Sitlinger, A. P., C. J. Lindsell, A. H. Ruffner, D. B. Wayne, K. W. Hart, A. T. Trott, C. J. Fichtenbaum, and M. S. Lyons. “Preliminary program evaluation of emergency department HIV prevention counseling.” Annals of Emergency Medicine 58, no. 1 SUPPL. (January 1, 2011). https://doi.org/10.1016/j.annemergmed.2011.03.036.Full Text
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