Recent Publications
Single-cell DNA methylation and 3D genome architecture in the human brain.
Journal Article Science (New York, N.Y.) · October 2023 Delineating the gene-regulatory programs underlying complex cell types is fundamental for understanding brain function in health and disease. Here, we comprehensively examined human brain cell epigenomes by probing DNA methylation and chromatin conformatio ... Full text CiteMutations of the histone linker H1-4 in neurodevelopmental disorders and functional characterization of neurons expressing C-terminus frameshift mutant H1.4.
Journal Article Hum Mol Genet · May 4, 2022 Rahman syndrome (RMNS) is a rare genetic disorder characterized by mild to severe intellectual disability, hypotonia, anxiety, autism spectrum disorder, vision problems, bone abnormalities and dysmorphic facies. RMNS is caused by de novo heterozygous mutat ... Full text Link to item CiteAuthor Correction: Comparative cellular analysis of motor cortex in human, marmoset and mouse.
Journal Article Nature · April 2022 Full text CiteRecent Grants
Chromatin dysregulation in neurodevelopmental disorders
ResearchResearch Assistant · Awarded by National Institutes of Health · 2024 - 2029View All Grants