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Current Duke Appointments & Affiliations


Recent Scholarly Works


Genetics and environment distinctively shape the human immune cell epigenome.

Journal article Nat Genet · February 2026 The epigenome of human immune cells is shaped by both genetics and environmental factors, yet the relative contributions of these influences remain incompletely characterized. Here we use single-nucleus methylation sequencing and assay for transposase-acce ... Full text Link to item Cite

Genetics and Environment Distinctively Shape the Human Immune Cell Epigenome.

Journal article bioRxiv · January 4, 2025 The epigenomic landscape of human immune cells is dynamically shaped by both genetic factors and environmental exposures. However, the relative contributions of these elements are still not fully understood. In this study, we employed single-nucleus methyl ... Full text Link to item Cite

Epigenetics and the timing of neuronal differentiation.

Journal article Curr Opin Neurobiol · December 2024 Epigenetic regulation of the genome is required for cell-type differentiation during organismal development and is especially important to generate the panoply of specialized cell types that comprise the brain. Here, we review how progressive changes in th ... Full text Link to item Cite
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Recent Grants


Chromatin dysregulation in neurodevelopmental disorders

ResearchResearch Assistant · Awarded by National Institute of Neurological Disorders and Stroke · 2024 - 2029

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