Andrew John Armstrong
Professor of Medicine
1. Predictors of sensitivity and clinical efficacy of therapies in advanced prostate cancer
2. Novel designs of clinical trials and pharmacodynamic/translational studies in prostate, kidney, bladder cancer
3. Pre-operative models for drug development of novel agents in human testing in prostate cancer
4. Novel therapies and drug development for prostate, renal, bladder, and testicular cancer
5. Design of rational combination therapies in men with metastatic hormone-refractory prostate cancer
6. PI3 kinase/mTOR inhibition in prostate cancer: mechanisms of sensitivity and resistance
7. Developing prognostic models for progression and survival in metastatic prostate cancer
8. Examining surrogate markers of mortality in metastatic prostate cancer
9. Clear cell and non-clear cell renal cell carcinoma: natural history, sensitivity to novel agents including mTOR and VEGF inhibition
2. Novel designs of clinical trials and pharmacodynamic/translational studies in prostate, kidney, bladder cancer
3. Pre-operative models for drug development of novel agents in human testing in prostate cancer
4. Novel therapies and drug development for prostate, renal, bladder, and testicular cancer
5. Design of rational combination therapies in men with metastatic hormone-refractory prostate cancer
6. PI3 kinase/mTOR inhibition in prostate cancer: mechanisms of sensitivity and resistance
7. Developing prognostic models for progression and survival in metastatic prostate cancer
8. Examining surrogate markers of mortality in metastatic prostate cancer
9. Clear cell and non-clear cell renal cell carcinoma: natural history, sensitivity to novel agents including mTOR and VEGF inhibition
Office Hours
Tuesdays, Wednesdays and Fridays. Contact Peggy Cook, my assistant at peggy.cook@dm.duke.edu for appointments. Or 919-668-4667.
Current Appointments & Affiliations
- Professor of Medicine, Medicine, Medical Oncology, Medicine 2018
- Associate Professor in Pharmacology and Cancer Biology, Pharmacology & Cancer Biology, Basic Science Departments 2015
- Professor in Surgery, Surgery, Urology, Surgery 2018
- Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 2006
Contact Information
- Duke Box 103861, Durham, NC 27710
- GSRB1 Room 3006, 905 La Salle St, Durham, NC 27710
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andrew.armstrong@duke.edu
(919) 668-8797
- Background
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Education, Training, & Certifications
- M.Sc., Johns Hopkins University 2008
- Fellowship, Division Of Oncology/Hematology, Johns Hopkins University School of Medicine 2003 - 2006
- Internship/Residency, General Internal Medicine, University of Pennsylvania, School of Medicine 2000 - 2003
- M.D., University of Virginia School of Medicine 2000
- B.S.E., Duke University 1996
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Duke Appointment History
- Associate Professor of Medicine, Medicine, Medical Oncology, Medicine 2014 - 2018
- Associate Professor in Surgery, Surgery, Urology, Surgery 2017 - 2018
- Associate Professor in Surgery, Surgery, Vascular and Endovascular Surgery, Surgery 2012 - 2017
- Associate Professor of Medicine, Medicine, Medical Oncology, Medicine 2012 - 2014
- Assistant Professor of Medicine, Medicine, Medical Oncology, Medicine 2006 - 2011
- Assistant Professor in Surgery, Surgery, Urology, Surgery 2007 - 2011
- Recognition
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In the News
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MAY 28, 2019 Duke Health News -
JUN 5, 2018 Duke Health News -
MAY 26, 2018 Duke Health News -
NOV 9, 2015 WRAL -
MAY 18, 2015 -
NOV 19, 2013
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- Expertise
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Global Scholarship
- Research
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Selected Grants
- A PHASE 1, MULTI-CENTER, OPEN-LABEL, DOSE FINDING STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF CC-94676 IN SUBJECTS WITH METASTATIC CASTRATION-RESISTANT PROSTATE CANCER awarded by Celgene Corporation 2021 - 2026
- Protocol No. 20180146 entitled "A Phase 1 Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of AMG 509 in Subjects With Metastatic Castration-Resistant Prostate Cancer awarded by Amgen, Inc. 2020 - 2025
- Clinical genomic predictive model of first line androgen receptor inhibitor therapy outcomes in men with mCRPC awarded by National Institutes of Health 2020 - 2025
- A Phase 3, Randomized, Double-blind Study of Pembrolizumab (MK-3475) Plus Docetaxel Plus Prednisone versus Placebo Plus Docetaxel Plus Prednisone in Participants with Chemotherapy-naive Metastatic Castration-Resistant Prostate Cancer awarded by Merck Sharp & Dohme 2019 - 2024
- Targeting convergent oncogenic signaling during AR inhibition to overcome metastasis and immune evasion in prostate cancer awarded by National Institutes of Health 2019 - 2024
- Study title: A Randomized, Double-blind, Placebo-controlled, Multicenter Phase III Study of Olaparib Plus Abiraterone Relative to Placebo Plus Abiraterone as First-line Therapy in Men with Metastatic Castration-resistant Prostate Cancer awarded by AstraZeneca AB 2019 - 2024
- A Phase 3, Randomized, Double-blind Trial of Pembrolizumab (MK-3475) Plus Enzalutamide Plus ADT Versus Placebo Plus Enzalutamide Plus ADT in Participants With Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) (KEYNOTE-991) awarded by Merck Sharp & Dohme 2020 - 2024
- ProSTAR: A Phase 1b/2 Study of CPI-1205, a Small Molecule Inhibitor of EZH2, Combined with Enzalutamide or Abiraterone/Prednisone in Patients with Metastatic Castration Resistant Prostate Cancer awarded by Constellation Pharmaceuticals 2019 - 2024
- VISION: An International, Prospective, Open-Label, Multicenter, Randomized Phase 3 Study of 177lu-Psma-617 in the Treatment of Patients with Progressive PSMA-Positive Metastatic Castration-Resistant Prostate Cancer (mCRPC) awarded by Endocyte, Inc. 2019 - 2024
- A Phase 2, Open-Label, Single-Arm Study of Pamiparib (BGB-290) for the Treatment of Patients with Metastatic Castration-Resistant Prostate Cancer (mCRPC) with Homologous Recombination Deficiency (HRD) (Beigene) awarded by BeiGene, Ltd 2020 - 2024
- Interrupting the aberrant cancer development sequence in epithelial cancer progression awarded by Prostate Cancer Foundation 2021 - 2024
- A Phase 2 Study of Nivolumab in combination with either Rucaparib, docetaxel, or enzalutamide in men with Castration-resistant metastaic prostate cancer (CheckMate 9KD: CHECKpoint pathway and nivoluMA awarded by Bristol-Myers Squibb Company 2018 - 2023
- A Phase II Study of Navarixin (MK-7123) in Combination with Pembrolizumab (MK-3475) in Participants with Selected Advanced/Metastatic Solid Tumors awarded by Merck Sharp & Dohme 2018 - 2023
- Targeting Convergent Mechanisms of Therapy Resistance, Metastasis, and Immune Evasion with CBP inhibitors awarded by FORMA Therapeutics, Inc. 2020 - 2022
- Targeting convergent mechanisms of castration resistant prostate cancer therapy resistance, metastasis, and immune evasion with AR-LDDs awarded by Celgene Corporation 2019 - 2022
- NEPC Trial PD-1 Inhibition in Neuroendocrine-like Prostate Cancer (PD-1 Inhibition or Combination Checkpoint Immuntherapy of Neuroedocrine_Like Prostate Cancer awarded by Pfizer, Inc. 2017 - 2022
- A Phase 1B, Open-Label Study of the Safety and Tolerability of Atezolizumab in Combination with Radium-223 Dichloride in Patients with Castrate-Resistant Prostate Cancer who have progressed followinIn awarded by Genentech, Inc. 2017 - 2022
- HOXB13 as a therapeutic target in prostate cancer awarded by Prostate Cancer Foundation 2020 - 2022
- Targeting the p38/Snail/PD-L1 axis in hormone-therapy resistance and metastasis awarded by Department of Defense 2018 - 2021
- PCRP Clinical Consortium: Duke University Clinical Research Site awarded by Department of Defense 2007 - 2021
- A Randomized Phase 2 Study of Sipuleucel-T with or without Radium-223 in Men with Asymptomatic or Minimally Symptomatic Bone-Metastatic Castrate Resistant Prostate Cancer awarded by Johns Hopkins University 2017 - 2021
- Plasma Angiome and Serum Androgens as Predictors of Overall Survival in Metastatic Prostate Cancer awarded by Department of Defense 2018 - 2021
- Plasma Angiome and Serum Androgens as Predictors of Overall Survival in Metastatic Prostate Cancer awarded by Department of Defense 2018 - 2021
- Defining the Relevant Immune Checkpoints Expressed on Metastatic Prostate Cancer Circulating Tumor Cells awarded by Janssen Research & Development, LLC 2016 - 2021
- A Phase 1b/2 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GS-5829 as a Single Agent and In Combination with Enzalutamide in Subjects with Metastatic Castrate-Resistanct Prostate Cancer awarded by Gilead Sciences, Inc. 2016 - 2020
- Targeting Convergent Mechanisms of Therapy Resistance, Metastasis, and Immune Evasion with CBP inhibitors awarded by FORMA Therapeutics, Inc. 2018 - 2020
- STREAM - Salvage Therapeutic Radiation with Enzalutamide and ADT in Men with Recurrent Prostate Cancer awarded by Astellas Pharma Global Development, Inc 2014 - 2020
- Development of Circulating Molecular Predictors of Chemotherapy and Novel Hormonal Therapy Benefit in Men with Metastatic Castration Resistant Prostate Cancer (mCRPC) awarded by Prostate Cancer Foundation 2014 - 2020
- A Phase III, Open Label, Randomized Study to Assess the Efficacy and Safety of Olaparib (Lynparza¿) Versus Enzalutamide or Abiraterone Acetate in Men with Metastatic Castration-Resistant Prostate Canc awarded by AstraZeneca Pharmaceuticals, LP 2018 - 2020
- Pharmacology Industry Internships for Ph.D. Students awarded by American Society for Pharmacology and Experimental Therapeutics 2017 - 2019
- Pharmacodynamic Study of Radium-223 in Men with Bone Metastatic Castration-Resistant Prostate Cancer (CRPC) awarded by Bayer Corporation 2014 - 2019
- A Phase 2 Trial of the Aurora Kinase A Inhibitor MLN8237 in Patients with Metastatic Castrate Resistant and Neuroendocrine Prostate Cancer awarded by Weill Medical College of Cornell University 2013 - 2019
- Testing the efficacy of AR degrading compounds in enzalutamide-resistant prostate cancer awarded by Arvinas Inc. 2017 - 2019
- AR variant regulation during EMT and disease progression awarded by National Institutes of Health 2015 - 2018
- TAX 3503, A prospective registry -A Randomized, Open label, Muiticenter, Phase III, 2 Arm Study of Androgen Deprivation with Leuprilode +/- Docetaxel for Clinically Asymptomatic Prostate Cancer Subjects with a Rising PSA Following D. local therapy awarded by Memorial Sloan-Kettering Cancer Center 2013 - 2017
- Developing and Validating Prognostic Models of Clinical Outcomes In Men With Castration Resistant Prostate Cancer awarded by National Institutes of Health 2011 - 2016
- Alternative splicing and epithelial-mesenchymal plasticity in prostate tumors awarded by National Institutes of Health 2008 - 2014
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External Relationships
- Astellas Pharma Inc.
- AstraZeneca
- Atheneum
- Bayer
- Bionest
- Bristol-Myers Squibb
- Cipla
- Clarion Healthcare
- Clovis Oncology
- Core2Ed
- Dendreon Valeant Corporation
- Firstword
- Global Guidepoint
- KeyQuest
- Merck Sharpe & Dohme (Merck & Co, USA)
- Neil Love CME
- Pfizer Inc.
- Ron Schlief Oncology
- Schlesinger Associates
- Slingshot insights
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Zhang, Tian, Anika Agarwal, R Garland Almquist, Daniella Runyambo, Sally Park, Elizabeth Bronson, Rengasamy Boominathan, et al. “Expression of immune checkpoints on circulating tumor cells in men with metastatic prostate cancer.” Biomark Res 9, no. 1 (February 18, 2021): 14. https://doi.org/10.1186/s40364-021-00267-y.Full Text Link to Item
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Armstrong, Andrew J., Andrew B. Nixon, Andrea Carmack, Timothy Eisen, Walter M. Stadler, Robert J. Jones, Jorge Garcia, et al. “Angiokines associated with outcomes after sunitinib or everolimus treatment in patients with non-clear cell renal cell carcinoma.” Clin Cancer Res, February 16, 2021. https://doi.org/10.1158/1078-0432.CCR-20-4504.Full Text Link to Item
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Halabi, Susan, and Andrew J. Armstrong. “Sarcomatoid Renal Cell Carcinoma: An Immune Checkpoint-responsive Subset?” Eur Urol, February 13, 2021. https://doi.org/10.1016/j.eururo.2021.01.042.Full Text Link to Item
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Armstrong, Andrew J., Xiaotong Li, Matthew Tucker, Shantao Li, Xinmeng Jasmine Mu, Kenneth Wha Eng, Andrea Sboner, Mark Rubin, and Mark Gerstein. “Molecular medicine tumor board: whole-genome sequencing to inform on personalized medicine for a man with advanced prostate cancer.” Prostate Cancer Prostatic Dis, February 10, 2021. https://doi.org/10.1038/s41391-021-00324-5.Full Text Link to Item
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Schaeffer, Edward, Sandy Srinivas, Emmanuel S. Antonarakis, Andrew J. Armstrong, Justin E. Bekelman, Heather Cheng, Anthony Victor D’Amico, et al. “NCCN Guidelines Insights: Prostate Cancer, Version 1.2021.” Journal of the National Comprehensive Cancer Network : Jnccn 19, no. 2 (February 2, 2021): 134–43. https://doi.org/10.6004/jnccn.2021.0008.Full Text
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Marshall, Catherine H., Wei Fu, Hao Wang, Jong Chul Park, Theodore L. DeWeese, Phuoc T. Tran, Daniel Y. Song, et al. “Randomized Phase II Trial of Sipuleucel-T with or without Radium-223 in Men with Bone-metastatic Castration-resistant Prostate Cancer.” Clin Cancer Res, January 15, 2021. https://doi.org/10.1158/1078-0432.CCR-20-4476.Full Text Link to Item
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Koontz, Bridget F., Karen E. Hoffman, Susan Halabi, Patrick Healy, Monika Anand, Daniel J. George, Michael R. Harrison, et al. “Combination of Radiation Therapy and Short-Term Androgen Blockade With Abiraterone Acetate Plus Prednisone for Men With High- and Intermediate-Risk Localized Prostate Cancer.” Int J Radiat Oncol Biol Phys, November 28, 2020. https://doi.org/10.1016/j.ijrobp.2020.11.059.Full Text Link to Item
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Powers, Eric, Georgia Sofia Karachaliou, Chester Kao, Michael R. Harrison, Christopher J. Hoimes, Daniel J. George, Andrew J. Armstrong, and Tian Zhang. “Novel therapies are changing treatment paradigms in metastatic prostate cancer.” J Hematol Oncol 13, no. 1 (October 28, 2020): 144. https://doi.org/10.1186/s13045-020-00978-z.Full Text Link to Item
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Stenzl, Arnulf, Curtis Dunshee, Ugo De Giorgi, Boris Alekseev, Taro Iguchi, Russell Z. Szmulewitz, Thomas W. Flaig, et al. “Effect of Enzalutamide plus Androgen Deprivation Therapy on Health-related Quality of Life in Patients with Metastatic Hormone-sensitive Prostate Cancer: An Analysis of the ARCHES Randomised, Placebo-controlled, Phase 3 Study.” Eur Urol 78, no. 4 (October 2020): 603–14. https://doi.org/10.1016/j.eururo.2020.03.019.Full Text Link to Item
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Armstrong, Andrew J., Ping Lin, Bertrand Tombal, Fred Saad, Celestia S. Higano, Anthony M. Joshua, Teresa Parli, Brad Rosbrook, Steve van Os, and Tomasz M. Beer. “Five-year Survival Prediction and Safety Outcomes with Enzalutamide in Men with Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer from the PREVAIL Trial.” Eur Urol 78, no. 3 (September 2020): 347–57. https://doi.org/10.1016/j.eururo.2020.04.061.Full Text Link to Item
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Lu, Changxue, Landon C. Brown, Emmanuel S. Antonarakis, Andrew J. Armstrong, and Jun Luo. “Androgen receptor variant-driven prostate cancer II: advances in laboratory investigations.” Prostate Cancer Prostatic Dis 23, no. 3 (September 2020): 381–97. https://doi.org/10.1038/s41391-020-0217-3.Full Text Link to Item
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Sartor, Oliver, Andrew J. Armstrong, Chiledum Ahaghotu, David G. McLeod, Matthew R. Cooperberg, David F. Penson, Philip W. Kantoff, et al. “Survival of African-American and Caucasian men after sipuleucel-T immunotherapy: outcomes from the PROCEED registry.” Prostate Cancer Prostatic Dis 23, no. 3 (September 2020): 517–26. https://doi.org/10.1038/s41391-020-0213-7.Full Text Link to Item
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Bu, Jiyoon, Ashita Nair, Luke J. Kubiatowicz, Michael J. Poellmann, Woo-Jin Jeong, Marco Reyes-Martinez, Andrew J. Armstrong, et al. “Surface engineering for efficient capture of circulating tumor cells in renal cell carcinoma: From nanoscale analysis to clinical application.” Biosens Bioelectron 162 (August 15, 2020): 112250. https://doi.org/10.1016/j.bios.2020.112250.Full Text Link to Item
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Wu, Mengxi, Po-Hsun Huang, Rui Zhang, Zhangming Mao, Chuyi Chen, Gabor Kemeny, Peng Li, et al. “Circulating Tumor Cell Phenotyping via High-Throughput Acoustic Separation.” Small 16, no. 34 (August 2020): e2004438. https://doi.org/10.1002/smll.202004438.Full Text Link to Item
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Freedland, Stephen J., Jenifer Allen, Aubrey Jarman, Taofik Oyekunle, Andrew J. Armstrong, Judd W. Moul, Howard M. Sandler, et al. “A Randomized Controlled Trial of a 6-Month Low-Carbohydrate Intervention on Disease Progression in Men with Recurrent Prostate Cancer: Carbohydrate and Prostate Study 2 (CAPS2).” Clin Cancer Res 26, no. 12 (June 15, 2020): 3035–43. https://doi.org/10.1158/1078-0432.CCR-19-3873.Full Text Link to Item
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Higano, Celestia S., Andrew J. Armstrong, Oliver Sartor, Nicholas J. Vogelzang, Philip W. Kantoff, David G. McLeod, Christopher M. Pieczonka, et al. “Reply to Potential underestimation of cerebrovascular events in the PROVENGE Registry for the Observation, Collection, and Evaluation of Experience Data.” Cancer 126, no. 12 (June 15, 2020): 2935–37. https://doi.org/10.1002/cncr.32785.Full Text Link to Item
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Gupta, Santosh, Daniel H. Hovelson, Gabor Kemeny, Susan Halabi, Wen-Chi Foo, Monika Anand, Jason A. Somarelli, et al. “Discordant and heterogeneous clinically relevant genomic alterations in circulating tumor cells vs plasma DNA from men with metastatic castration resistant prostate cancer.” Genes Chromosomes Cancer 59, no. 4 (April 2020): 225–39. https://doi.org/10.1002/gcc.22824.Full Text Link to Item
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George, Daniel J., Susan Halabi, Patrick Healy, Darius Jonasch, Monika Anand, Julia Rasmussen, Sarah Y. Wood, Charles Spritzer, John F. Madden, and Andrew J. Armstrong. “Phase 2 clinical trial of TORC1 inhibition with everolimus in men with metastatic castration-resistant prostate cancer.” Urol Oncol 38, no. 3 (March 2020): 79.e15-79.e22. https://doi.org/10.1016/j.urolonc.2019.08.015.Full Text Link to Item
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Armstrong, Andrew J., Mohammed Al-Adhami, Ping Lin, Teresa Parli, Jennifer Sugg, Joyce Steinberg, Bertrand Tombal, et al. “Association Between New Unconfirmed Bone Lesions and Outcomes in Men With Metastatic Castration-Resistant Prostate Cancer Treated With Enzalutamide: Secondary Analysis of the PREVAIL and AFFIRM Randomized Clinical Trials.” Jama Oncol 6, no. 2 (February 1, 2020): 217–25. https://doi.org/10.1001/jamaoncol.2019.4636.Full Text Link to Item
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Armstrong, Andrew J., Jun Luo, David M. Nanus, Paraskevi Giannakakou, Russell Z. Szmulewitz, Daniel C. Danila, Patrick Healy, et al. “Prospective Multicenter Study of Circulating Tumor Cell AR-V7 and Taxane Versus Hormonal Treatment Outcomes in Metastatic Castration-Resistant Prostate Cancer.” Jco Precis Oncol 4 (2020). https://doi.org/10.1200/PO.20.00200.Full Text Link to Item
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Li, Yanjing, Yiping He, William Butler, Lingfan Xu, Yan Chang, Kefeng Lei, Hong Zhang, et al. “Targeting cellular heterogeneity with CXCR2 blockade for the treatment of therapy-resistant prostate cancer.” Sci Transl Med 11, no. 521 (December 4, 2019). https://doi.org/10.1126/scitranslmed.aax0428.Full Text Link to Item
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Higano, Celestia S., Andrew J. Armstrong, A Oliver Sartor, Nicholas J. Vogelzang, Philip W. Kantoff, David G. McLeod, Christopher M. Pieczonka, et al. “Real-world outcomes of sipuleucel-T treatment in PROCEED, a prospective registry of men with metastatic castration-resistant prostate cancer.” Cancer 125, no. 23 (December 1, 2019): 4172–80. https://doi.org/10.1002/cncr.32445.Full Text Link to Item
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Holl, Eda K., Megan A. McNamara, Patrick Healy, Monika Anand, Raoul S. Concepcion, Coleman D. Breland, Igor Dumbudze, et al. “Prolonged PSA stabilization and overall survival following sipuleucel-T monotherapy in metastatic castration-resistant prostate cancer patients.” Prostate Cancer Prostatic Dis 22, no. 4 (December 2019): 588–92. https://doi.org/10.1038/s41391-019-0144-3.Full Text Link to Item
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Mota, Jose Mauricio, Andrew J. Armstrong, Steven M. Larson, Josef J. Fox, and Michael J. Morris. “Measuring the unmeasurable: automated bone scan index as a quantitative endpoint in prostate cancer clinical trials.” Prostate Cancer Prostatic Dis 22, no. 4 (December 2019): 522–30. https://doi.org/10.1038/s41391-019-0151-4.Full Text Link to Item
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Armstrong, Andrew J., Russell Z. Szmulewitz, Daniel P. Petrylak, Jeffrey Holzbeierlein, Arnauld Villers, Arun Azad, Antonio Alcaraz, et al. “ARCHES: A Randomized, Phase III Study of Androgen Deprivation Therapy With Enzalutamide or Placebo in Men With Metastatic Hormone-Sensitive Prostate Cancer.” J Clin Oncol 37, no. 32 (November 10, 2019): 2974–86. https://doi.org/10.1200/JCO.19.00799.Full Text Link to Item
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Yuan, Fuwen, William Hankey, Dayong Wu, Hongyan Wang, Jason Somarelli, Andrew J. Armstrong, Jiaoti Huang, Zhong Chen, and Qianben Wang. “Molecular determinants for enzalutamide-induced transcription in prostate cancer.” Nucleic Acids Res 47, no. 19 (November 4, 2019): 10104–14. https://doi.org/10.1093/nar/gkz790.Full Text Open Access Copy Link to Item
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Armstrong, Andrew J., Ping Lin, Celestia S. Higano, Peter Iversen, Cora N. Sternberg, Bertrand Tombal, De Phung, Teresa Parli, Andrew Krivoshik, and Tomasz M. Beer. “Prognostic Association of Prostate-specific Antigen Decline with Clinical Outcomes in Men with Metastatic Castration-resistant Prostate Cancer Treated with Enzalutamide in a Randomized Clinical Trial.” Eur Urol Oncol 2, no. 6 (November 2019): 677–84. https://doi.org/10.1016/j.euo.2018.11.005.Full Text Link to Item
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George, Daniel J., Susan Halabi, Patrick Healy, Ian Barak, Carolyn Winters, Monika Anand, Rhonda Wilder, et al. “Phase 1b trial of docetaxel, prednisone, and pazopanib in men with metastatic castration-resistant prostate cancer.” Prostate 79, no. 15 (November 2019): 1752–61. https://doi.org/10.1002/pros.23899.Full Text Link to Item
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Zhu, Jason, Matthew Tucker, Daniele Marin, Rajan T. Gupta, Patrick Healy, Michael Humeniuk, Casey Jarvis, et al. “Clinical utility of FoundationOne tissue molecular profiling in men with metastatic prostate cancer.” Urol Oncol 37, no. 11 (November 2019): 813.e1-813.e9. https://doi.org/10.1016/j.urolonc.2019.06.015.Full Text Link to Item
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Freedland, Stephen J., Lauren Howard, Jenifer Allen, Jordan Smith, Jennifer Stout, William Aronson, Brant A. Inman, et al. “A lifestyle intervention of weight loss via a low-carbohydrate diet plus walking to reduce metabolic disturbances caused by androgen deprivation therapy among prostate cancer patients: carbohydrate and prostate study 1 (CAPS1) randomized controlled trial.” Prostate Cancer Prostatic Dis 22, no. 3 (September 2019): 428–37. https://doi.org/10.1038/s41391-019-0126-5.Full Text Link to Item
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Armstrong, Andrew J., Susan Halabi, Jun Luo, David M. Nanus, Howard I. Scher, Emmanuel S. Antonarakis, and Daniel J. George. “Reply to L. Dirix, B. De Laere et al, and A. Sharp et al.” J Clin Oncol 37, no. 24 (August 20, 2019): 2184–86. https://doi.org/10.1200/JCO.19.01230.Full Text Link to Item
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Tucker, Matthew D., Jason Zhu, Daniele Marin, Rajan T. Gupta, Santosh Gupta, William R. Berry, Sundhar Ramalingam, et al. “Pembrolizumab in men with heavily treated metastatic castrate-resistant prostate cancer.” Cancer Med 8, no. 10 (August 2019): 4644–55. https://doi.org/10.1002/cam4.2375.Full Text Link to Item
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McNamara, Megan Ann, Taofik Oyekunle, Bennett B. Chin, Jorge Oldan, Aseem Anand, Michala Ritz, Lindsey Shantzer, Monika Anand, Andrew J. Armstrong, and Daniel J. George. “Patterns of response and progression in bone and soft tissue during and after treatment with radium-223 for metastatic castrate-resistant prostate cancer.” Prostate 79, no. 10 (July 2019): 1106–16. https://doi.org/10.1002/pros.23822.Full Text Link to Item
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Jolly, Mohit Kumar, Kathryn E. Ware, Shengnan Xu, Shivee Gilja, Samantha Shetler, Yanjun Yang, Xueyang Wang, et al. “E-Cadherin Represses Anchorage-Independent Growth in Sarcomas through Both Signaling and Mechanical Mechanisms.” Mol Cancer Res 17, no. 6 (June 2019): 1391–1402. https://doi.org/10.1158/1541-7786.MCR-18-0763.Full Text Link to Item
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Labriola, Matthew K., Kristen A. Batich, Jason Zhu, Megan A. McNamara, Michael R. Harrison, Andrew J. Armstrong, Daniel J. George, and Tian Zhang. “Immunotherapy Is Changing First-Line Treatment of Metastatic Renal-Cell Carcinoma.” Clin Genitourin Cancer 17, no. 3 (June 2019): e513–21. https://doi.org/10.1016/j.clgc.2019.01.017.Full Text Link to Item
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Armstrong, Andrew J., Susan Halabi, Jun Luo, David M. Nanus, Paraskevi Giannakakou, Russell Z. Szmulewitz, Daniel C. Danila, et al. “Prospective Multicenter Validation of Androgen Receptor Splice Variant 7 and Hormone Therapy Resistance in High-Risk Castration-Resistant Prostate Cancer: The PROPHECY Study.” J Clin Oncol 37, no. 13 (May 1, 2019): 1120–29. https://doi.org/10.1200/JCO.18.01731.Full Text Link to Item
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Mohler, James L., Emmanuel S. Antonarakis, Andrew J. Armstrong, Anthony V. D’Amico, Brian J. Davis, Tanya Dorff, James A. Eastham, et al. “Prostate Cancer, Version 2.2019, NCCN Clinical Practice Guidelines in Oncology.” J Natl Compr Canc Netw 17, no. 5 (May 1, 2019): 479–505. https://doi.org/10.6004/jnccn.2019.0023.Full Text Link to Item
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Sonpavde, Guru, Neeraj Agarwal, Gregory Russell Pond, Rebecca J. Nagy, Roberto H. Nussenzveig, Andrew W. Hahn, Oliver Sartor, et al. “Circulating tumor DNA alterations in patients with metastatic castration-resistant prostate cancer.” Cancer 125, no. 9 (May 1, 2019): 1459–69. https://doi.org/10.1002/cncr.31959.Full Text Link to Item
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Xu, Shengnan, Kathryn E. Ware, Yuantong Ding, So Young Kim, Maya U. Sheth, Sneha Rao, Wesley Chan, et al. “An Integrative Systems Biology and Experimental Approach Identifies Convergence of Epithelial Plasticity, Metabolism, and Autophagy to Promote Chemoresistance.” J Clin Med 8, no. 2 (February 7, 2019). https://doi.org/10.3390/jcm8020205.Full Text Link to Item
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Armstrong, Andrew J., Orjan Nordle, and Michael Morris. “Assessing the Prognostic Value of the Automated Bone Scan Index for Prostate Cancer-Reply.” Jama Oncol 5, no. 2 (February 1, 2019): 270–71. https://doi.org/10.1001/jamaoncol.2018.5874.Full Text Link to Item
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Jolly, Mohit Kumar, Jason A. Somarelli, Maya Sheth, Adrian Biddle, Satyendra C. Tripathi, Andrew J. Armstrong, Samir M. Hanash, Sharmila A. Bapat, Annapoorni Rangarajan, and Herbert Levine. “Hybrid epithelial/mesenchymal phenotypes promote metastasis and therapy resistance across carcinomas.” Pharmacol Ther 194 (February 2019): 161–84. https://doi.org/10.1016/j.pharmthera.2018.09.007.Full Text Link to Item
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Zhang, Tian, Daniel J. George, and Andrew J. Armstrong. “Precision Medicine Approaches When Prostate Cancer Akts Up.” Clin Cancer Res 25, no. 3 (February 1, 2019): 901–3. https://doi.org/10.1158/1078-0432.CCR-18-2491.Full Text Link to Item
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Armstrong, Andrew J., Santosh Gupta, Patrick Healy, Gabor Kemeny, Beth Leith, Michael R. Zalutsky, Charles Spritzer, et al. “Pharmacodynamic study of radium-223 in men with bone metastatic castration resistant prostate cancer.” Plos One 14, no. 5 (January 2019): e0216934. https://doi.org/10.1371/journal.pone.0216934.Full Text
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Beltran, Himisha, Clara Oromendia, Daniel C. Danila, Bruce Montgomery, Christopher Hoimes, Russell Z. Szmulewitz, Ulka Vaishampayan, et al. “A Phase II Trial of the Aurora Kinase A Inhibitor Alisertib for Patients with Castration-resistant and Neuroendocrine Prostate Cancer: Efficacy and Biomarkers.” Clin Cancer Res 25, no. 1 (January 1, 2019): 43–51. https://doi.org/10.1158/1078-0432.CCR-18-1912.Full Text Link to Item
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Zhang, Tian, Andrew J. Armstrong, Daniel J. George, and Jiaoti Huang. “The promise of immunotherapy in genitourinary malignancies.” Precis Clin Med 1, no. 3 (December 2018): 97–101. https://doi.org/10.1093/pcmedi/pby018.Full Text Link to Item
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Armstrong, A. J., P. Lin, C. S. Higano, C. N. Sternberg, G. Sonpavde, B. Tombal, A. J. Templeton, et al. “Development and validation of a prognostic model for overall survival in chemotherapy-naïve men with metastatic castration-resistant prostate cancer.” Ann Oncol 29, no. 11 (November 1, 2018): 2200–2207. https://doi.org/10.1093/annonc/mdy406.Full Text Link to Item
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Armstrong, Andrew J. “Updates in advanced prostate cancer 2018.” Prostate Cancer and Prostatic Diseases 21, no. 4 (November 2018): 449–50. https://doi.org/10.1038/s41391-018-0100-7.Full Text
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Brown, Landon C., Guru Sonpavde, and Andrew J. Armstrong. “Can RECIST response predict success in phase 3 trials in men with metastatic castration-resistant prostate cancer?” Prostate Cancer Prostatic Dis 21, no. 3 (September 2018): 419–30. https://doi.org/10.1038/s41391-018-0049-6.Full Text Link to Item
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McNamara, Megan, Christopher Sweeney, Emmanuel S. Antonarakis, and Andrew J. Armstrong. “The evolving landscape of metastatic hormone-sensitive prostate cancer: a critical review of the evidence for adding docetaxel or abiraterone to androgen deprivation.” Prostate Cancer Prostatic Dis 21, no. 3 (September 2018): 306–18. https://doi.org/10.1038/s41391-017-0014-9.Full Text Link to Item
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Wu, Mengxi, Po-Hsun Huang, Rui Zhang, Zhangming Mao, Chuyi Chen, Gabor Kemeny, Peng Li, et al. “Circulating Tumor Cell Phenotyping via High-Throughput Acoustic Separation.” Small 14, no. 32 (August 2018): e1801131. https://doi.org/10.1002/smll.201801131.Full Text Link to Item
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Armstrong, Andrew J., Aseem Anand, Lars Edenbrandt, Eva Bondesson, Anders Bjartell, Anders Widmark, Cora N. Sternberg, et al. “Phase 3 Assessment of the Automated Bone Scan Index as a Prognostic Imaging Biomarker of Overall Survival in Men With Metastatic Castration-Resistant Prostate Cancer: A Secondary Analysis of a Randomized Clinical Trial.” Jama Oncol 4, no. 7 (July 1, 2018): 944–51. https://doi.org/10.1001/jamaoncol.2018.1093.Full Text Link to Item
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Fantony, Joseph J., Lauren E. Howard, Ilona Csizmadi, Andrew J. Armstrong, Amy L. Lark, Colette Galet, William J. Aronson, and Stephen J. Freedland. “Is Ki67 prognostic for aggressive prostate cancer? A multicenter real-world study.” Biomark Med 12, no. 7 (July 2018): 727–36. https://doi.org/10.2217/bmm-2017-0322.Full Text Link to Item
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Sumanasuriya, Semini, Aurelius Omlin, Andrew Armstrong, Gerhardt Attard, Kim N. Chi, Charlotte L. Bevan, Aki Shibakawa, et al. “Consensus Statement on Circulating Biomarkers for Advanced Prostate Cancer.” Eur Urol Oncol 1, no. 2 (June 2018): 151–59. https://doi.org/10.1016/j.euo.2018.02.009.Full Text Link to Item
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Rathkopf, Dana E., Tomasz M. Beer, Yohann Loriot, Celestia S. Higano, Andrew J. Armstrong, Cora N. Sternberg, Johann S. de Bono, et al. “Radiographic Progression-Free Survival as a Clinically Meaningful End Point in Metastatic Castration-Resistant Prostate Cancer: The PREVAIL Randomized Clinical Trial.” Jama Oncol 4, no. 5 (May 1, 2018): 694–701. https://doi.org/10.1001/jamaoncol.2017.5808.Full Text Link to Item
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Humeniuk, Michael S., Rajan T. Gupta, Patrick Healy, Megan McNamara, Sundhar Ramalingam, Michael Harrison, Daniel George, Tian Zhang, Yuan Wu, and Andrew J. Armstrong. “Platinum sensitivity in metastatic prostate cancer: does histology matter?” Prostate Cancer Prostatic Dis 21, no. 1 (April 2018): 92–99. https://doi.org/10.1038/s41391-017-0017-6.Full Text Link to Item
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Austin, R Garland, Tony Jun Huang, Mengxi Wu, Andrew J. Armstrong, and Tian Zhang. “Clinical utility of non-EpCAM based circulating tumor cell assays.” Adv Drug Deliv Rev 125 (February 1, 2018): 132–42. https://doi.org/10.1016/j.addr.2018.01.013.Full Text Link to Item
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Zhu, Jason, Andrew J. Armstrong, Terence W. Friedlander, Won Kim, Sumanta K. Pal, Daniel J. George, and Tian Zhang. “Biomarkers of immunotherapy in urothelial and renal cell carcinoma: PD-L1, tumor mutational burden, and beyond.” J Immunother Cancer 6, no. 1 (January 25, 2018): 4. https://doi.org/10.1186/s40425-018-0314-1.Full Text Open Access Copy Link to Item
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Armstrong, A. J., E. S. Antonarakis, M. -. E. Taplin, W. K. Kelly, H. Beltran, K. Fizazi, W. L. Dahut, et al. “Naming disease states for clinical utility in prostate cancer: a rose by any other name might not smell as sweet.” Ann Oncol 29, no. 1 (January 1, 2018): 23–25. https://doi.org/10.1093/annonc/mdx648.Full Text Link to Item
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Taplin, Mary-Ellen, Andrew J. Armstrong, Ping Lin, Andrew Krivoshik, De Phung, Teresa Parli, Bertrand Tombal, and Tomasz M. Beer. “Clinical Outcomes of Chemotherapy Naïve Men with Metastatic Castration Resistant Prostate Cancer and Low Baseline Prostate Specific Antigen Treated with Enzalutamide vs Placebo.” J Urol 198, no. 6 (December 2017): 1324–32. https://doi.org/10.1016/j.juro.2017.07.071.Full Text Link to Item
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Zhu, Jason, Matthew Tucker, Endi Wang, Joel S. Grossman, Andrew J. Armstrong, Daniel J. George, and Tian Zhang. “Acute Myeloid Leukemia After Olaparib Treatment in Metastatic Castration-Resistant Prostate Cancer.” Clin Genitourin Cancer 15, no. 6 (December 2017): e1137–41. https://doi.org/10.1016/j.clgc.2017.07.005.Full Text Open Access Copy Link to Item
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Zhang, Tian, and Andrew J. Armstrong. “The Who, What, and How of Cabazitaxel Treatment in Metastatic Castration-Resistant Prostate Cancer.” J Clin Oncol 35, no. 28 (October 1, 2017): 3175–77. https://doi.org/10.1200/JCO.2017.74.7931.Full Text Link to Item
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Humeniuk, Michael S., Tian Zhang, and Andrew J. Armstrong. “Exploiting DNA damage without repair: The activity of platinum chemotherapy in BRCA-mutated prostate cancers.” Cancer 123, no. 18 (September 15, 2017): 3441–44. https://doi.org/10.1002/cncr.30806.Full Text Link to Item
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Humeniuk, Michael S., and Andrew J. Armstrong. “RECISTing the Temptation to Prematurely Stop Nivolumab.” Eur Urol 72, no. 3 (September 2017): 377–78. https://doi.org/10.1016/j.eururo.2017.04.021.Full Text Link to Item
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Armstrong, Andrew J., Fred Saad, De Phung, Carl Dmuchowski, Neal D. Shore, Karim Fizazi, Mohammad Hirmand, David Forer, Howard I. Scher, and Johann De Bono. “Clinical outcomes and survival surrogacy studies of prostate-specific antigen declines following enzalutamide in men with metastatic castration-resistant prostate cancer previously treated with docetaxel.” Cancer 123, no. 12 (June 15, 2017): 2303–11. https://doi.org/10.1002/cncr.30587.Full Text Link to Item
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Bryce, A. H., J. J. Alumkal, A. Armstrong, C. S. Higano, P. Iversen, C. N. Sternberg, D. Rathkopf, et al. “Radiographic progression with nonrising PSA in metastatic castration-resistant prostate cancer: post hoc analysis of PREVAIL.” Prostate Cancer Prostatic Dis 20, no. 2 (June 2017): 221–27. https://doi.org/10.1038/pcan.2016.71.Full Text Link to Item
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Ramalingam, Sundhar, Michael S. Humeniuk, Rachel Hu, Julia Rasmussen, Patrick Healy, Yuan Wu, Michael R. Harrison, Andrew J. Armstrong, Daniel J. George, and Tian Zhang. “Prostate-specific antigen response in black and white patients treated with abiraterone acetate for metastatic castrate-resistant prostate cancer.” Urol Oncol 35, no. 6 (June 2017): 418–24. https://doi.org/10.1016/j.urolonc.2016.12.016.Full Text Link to Item
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Ware, Kathryn E., Shivee Gilja, Shenghan Xu, Samantha Shetler, Mohit K. Jolly, Xueyang Wang, Suzanne Bartholf Dewitt, et al. “Induction of Mesenchymal-Epithelial Transitions in Sarcoma Cells.” J Vis Exp, no. 122 (April 7, 2017). https://doi.org/10.3791/55520.Full Text Link to Item
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Sonpavde, Guru, and Andrew J. Armstrong. “Drug development in prostate cancer: time to embrace RECIST?” Lancet Oncol 18, no. 4 (April 2017): 419–21. https://doi.org/10.1016/S1470-2045(17)30149-3.Full Text Link to Item
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Armstrong, Andrew J. “Prognostic and predictive biomarkers in metastatic castration-resistant prostate cancer.” Clin Adv Hematol Oncol 15, no. 3 (March 2017): 184–88.Link to Item
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Gupta, Santosh, Jing Li, Gabor Kemeny, Rhonda L. Bitting, Joshua Beaver, Jason A. Somarelli, Kathryn E. Ware, Simon Gregory, and Andrew J. Armstrong. “Whole Genomic Copy Number Alterations in Circulating Tumor Cells from Men with Abiraterone or Enzalutamide-Resistant Metastatic Castration-Resistant Prostate Cancer.” Clin Cancer Res 23, no. 5 (March 1, 2017): 1346–57. https://doi.org/10.1158/1078-0432.CCR-16-1211.Full Text Link to Item
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Penson, David F., Andrew J. Armstrong, Raoul Concepcion, Neeraj Agarwal, Carl Olsson, Lawrence Karsh, Curtis Dunshee, et al. “Reply to M.A.N. Şendur et al and J. Michels.” J Clin Oncol 35, no. 1 (January 2017): 123. https://doi.org/10.1200/JCO.2016.69.9371.Full Text Link to Item
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Ramalingam, Sundhar, Adva Eisenberg, Wen Chi Foo, Jennifer Freedman, Andrew J. Armstrong, Larry G. Moss, and Michael R. Harrison. “Treatment-related neuroendocrine prostate cancer resulting in Cushing's syndrome.” Int J Urol 23, no. 12 (December 2016): 1038–41. https://doi.org/10.1111/iju.13225.Full Text Link to Item
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Armstrong, Andrew J. “Predictive medicine: Using circulating biomarkers to guide management of patients with genitourinary cancers.” Urol Oncol 34, no. 11 (November 2016): 488–89. https://doi.org/10.1016/j.urolonc.2016.09.009.Full Text Link to Item
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Beltran, H., D. Danila, B. Montgomery, R. Szmulewitz, U. Vaishampayan, A. Armstrong, M. Stein, et al. “A phase 2 study of the aurora kinase A inhibitor alisertib for patients with neuroendocrine prostate cancer (NEPC).” Annals of Oncology 27 (October 1, 2016): vi565. https://doi.org/10.1093/annonc/mdw435.21.Full Text
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Evans, Christopher P., Celestia S. Higano, Thomas Keane, Gerald Andriole, Fred Saad, Peter Iversen, Kurt Miller, et al. “The PREVAIL Study: Primary Outcomes by Site and Extent of Baseline Disease for Enzalutamide-treated Men with Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer.” Eur Urol 70, no. 4 (October 2016): 675–83. https://doi.org/10.1016/j.eururo.2016.03.017.Full Text Link to Item
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Somarelli, Jason A., Samantha Shetler, Mohit K. Jolly, Xueyang Wang, Suzanne Bartholf Dewitt, Alexander J. Hish, Shivee Gilja, et al. “Mesenchymal-Epithelial Transition in Sarcomas Is Controlled by the Combinatorial Expression of MicroRNA 200s and GRHL2.” Mol Cell Biol 36, no. 19 (October 1, 2016): 2503–13. https://doi.org/10.1128/MCB.00373-16.Full Text Open Access Copy Link to Item
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Stenzl, A., A. Krivoshik, B. Baron, M. Hirmand, and A. Armstrong. “Efficacy and safety of enzalutamide plus androgen deprivation therapy vs placebo plus androgen deprivation therapy in men with metastatic hormone-sensitive prostate cancer: the ongoing ARCHES trial.” Annals of Oncology 27 (October 1, 2016): vi262. https://doi.org/10.1093/annonc/mdw372.51.Full Text
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Shields Iv, C Wyatt, Jeffrey L. Wang, Korine A. Ohiri, Eric D. Essoyan, Benjamin B. Yellen, Andrew J. Armstrong, and Gabriel P. López. “Magnetic separation of acoustically focused cancer cells from blood for magnetographic templating and analysis.” Lab Chip 16, no. 19 (September 21, 2016): 3833–44. https://doi.org/10.1039/c6lc00719h.Full Text Link to Item
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Antonarakis, E. S., A. J. Armstrong, S. M. Dehm, and J. Luo. “Androgen receptor variant-driven prostate cancer: clinical implications and therapeutic targeting.” Prostate Cancer Prostatic Dis 19, no. 3 (September 2016): 231–41. https://doi.org/10.1038/pcan.2016.17.Full Text Link to Item
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Somarelli, J. A., D. Schaeffer, M. S. Marengo, T. Bepler, D. Rouse, K. E. Ware, A. J. Hish, et al. “Distinct routes to metastasis: plasticity-dependent and plasticity-independent pathways.” Oncogene 35, no. 33 (August 18, 2016): 4302–11. https://doi.org/10.1038/onc.2015.497.Full Text Open Access Copy Link to Item
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Ware, Kathryn E., Jason A. Somarelli, Daneen Schaeffer, Jing Li, Tian Zhang, Sally Park, Steven R. Patierno, et al. “Snail promotes resistance to enzalutamide through regulation of androgen receptor activity in prostate cancer.” Oncotarget 7, no. 31 (August 2, 2016): 50507–21. https://doi.org/10.18632/oncotarget.10476.Full Text Open Access Copy Link to Item
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Penson, David F., Andrew J. Armstrong, Raoul Concepcion, Neeraj Agarwal, Carl Olsson, Lawrence Karsh, Curtis Dunshee, et al. “Enzalutamide Versus Bicalutamide in Castration-Resistant Prostate Cancer: The STRIVE Trial.” J Clin Oncol 34, no. 18 (June 20, 2016): 2098–2106. https://doi.org/10.1200/JCO.2015.64.9285.Full Text Link to Item
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Sonpavde, Guru, Gregory R. Pond, Arnoud J. Templeton, Abderrahim Fandi, Bertrand Tombal, Mark Rosenthal, Andrew J. Armstrong, and Daniel P. Petrylak. “Association Between RECIST Changes and Survival in Patients with Metastatic Castration-resistant Prostate Cancer Receiving Docetaxel.” Eur Urol 69, no. 6 (June 2016): 980–83. https://doi.org/10.1016/j.eururo.2015.10.008.Full Text Link to Item
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Zhang, Tian, Rengasamy Boominathan, Brad Foulk, Chandra Rao, Gabor Kemeny, John H. Strickler, James L. Abbruzzese, et al. “Development of a Novel c-MET-Based CTC Detection Platform.” Mol Cancer Res 14, no. 6 (June 2016): 539–47. https://doi.org/10.1158/1541-7786.MCR-16-0011.Full Text Open Access Copy Link to Item
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Ramalingam, Sundhar, David J. Sermer, Rajan Gupta, Patrick Healy, Yuan Wu, Daniel J. George, Andrew J. Armstrong, and Michael Roger Harrison. “Changes in skeletal muscle cross sectional area (CSA) in patients with metastatic castration-resistant prostate cancer (mCRPC) treated with enzalutamide (ENZ).” Journal of Clinical Oncology 34, no. 15_suppl (May 20, 2016): e16601–e16601. https://doi.org/10.1200/jco.2016.34.15_suppl.e16601.Full Text
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Halabi, Susan, William Kevin Kelly, Hua Ma, Haojin Zhou, Nicole C. Solomon, Karim Fizazi, Catherine M. Tangen, et al. “Meta-Analysis Evaluating the Impact of Site of Metastasis on Overall Survival in Men With Castration-Resistant Prostate Cancer.” J Clin Oncol 34, no. 14 (May 10, 2016): 1652–59. https://doi.org/10.1200/JCO.2015.65.7270.Full Text Link to Item
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Scher, Howard I., Michael J. Morris, Walter M. Stadler, Celestia Higano, Ethan Basch, Karim Fizazi, Emmanuel S. Antonarakis, et al. “Trial Design and Objectives for Castration-Resistant Prostate Cancer: Updated Recommendations From the Prostate Cancer Clinical Trials Working Group 3.” J Clin Oncol 34, no. 12 (April 20, 2016): 1402–18. https://doi.org/10.1200/JCO.2015.64.2702.Full Text Link to Item
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Armstrong, A. J., P. Healy, S. Halabi, R. Vollmer, A. Lark, G. Kemeny, K. Ware, and S. J. Freedland. “Evaluation of an epithelial plasticity biomarker panel in men with localized prostate cancer.” Prostate Cancer Prostatic Dis 19, no. 1 (March 2016): 40–45. https://doi.org/10.1038/pcan.2015.46.Full Text Open Access Copy Link to Item
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Armstrong, Andrew J., Susan Halabi, Tim Eisen, Samuel Broderick, Walter M. Stadler, Robert J. Jones, Jorge A. Garcia, et al. “Everolimus versus sunitinib for patients with metastatic non-clear cell renal cell carcinoma (ASPEN): a multicentre, open-label, randomised phase 2 trial.” Lancet Oncol 17, no. 3 (March 2016): 378–88. https://doi.org/10.1016/S1470-2045(15)00515-X.Full Text Link to Item
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Graff, J. N., G. Baciarello, A. J. Armstrong, C. S. Higano, P. Iversen, T. W. Flaig, D. Forer, et al. “Efficacy and safety of enzalutamide in patients 75 years or older with chemotherapy-naive metastatic castration-resistant prostate cancer: results from PREVAIL.” Ann Oncol 27, no. 2 (February 2016): 286–94. https://doi.org/10.1093/annonc/mdv542.Full Text Link to Item
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Mehta, Amit R., and Andrew J. Armstrong. “Tasquinimod in the treatment of castrate-resistant prostate cancer - current status and future prospects.” Ther Adv Urol 8, no. 1 (February 2016): 9–18. https://doi.org/10.1177/1756287215603558.Full Text Link to Item
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Tay, Kae Jack, Judd W. Moul, and Andrew J. Armstrong. “Management of Prostate Cancer in the Elderly.” Clin Geriatr Med 32, no. 1 (February 2016): 113–32. https://doi.org/10.1016/j.cger.2015.08.001.Full Text Link to Item
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Mohler, James L., Andrew J. Armstrong, Robert R. Bahnson, Anthony Victor D’Amico, Brian J. Davis, James A. Eastham, Charles A. Enke, et al. “Prostate Cancer, Version 1.2016.” J Natl Compr Canc Netw 14, no. 1 (January 2016): 19–30. https://doi.org/10.6004/jnccn.2016.0004.Full Text Link to Item
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Zhang, Tian, and Andrew J. Armstrong. “Clinical Utility of Circulating Tumor Cells in Advanced Prostate Cancer.” Curr Oncol Rep 18, no. 1 (January 2016): 3. https://doi.org/10.1007/s11912-015-0490-9.Full Text Link to Item
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Zhang, Tian, and Andrew J. Armstrong. “Docetaxel Resistance in Prostate Cancer: Taking It Up a Notch.” Clin Cancer Res 21, no. 20 (October 15, 2015): 4505–7. https://doi.org/10.1158/1078-0432.CCR-15-1613.Full Text Open Access Copy Link to Item
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Hussain, Maha, Dana Rathkopf, Glenn Liu, Andrew Armstrong, Wm Kevin Kelly, Anna Ferrari, John Hainsworth, et al. “A randomised non-comparative phase II trial of cixutumumab (IMC-A12) or ramucirumab (IMC-1121B) plus mitoxantrone and prednisone in men with metastatic docetaxel-pretreated castration-resistant prostate cancer.” Eur J Cancer 51, no. 13 (September 2015): 1714–24. https://doi.org/10.1016/j.ejca.2015.05.019.Full Text Link to Item
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Kanesvaran, Ravindran, Kevin Watt, James D. Turnbull, Andrew J. Armstrong, Michael Cohen Wolkowiez, and Daniel J. George. “A Single-Arm Phase 1b Study of Everolimus and Sunitinib in Patients With Advanced Renal Cell Carcinoma.” Clin Genitourin Cancer 13, no. 4 (August 2015): 319–27. https://doi.org/10.1016/j.clgc.2014.12.011.Full Text Link to Item
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Zhang, Tian, Mallika S. Dhawan, Patrick Healy, Daniel J. George, Michael R. Harrison, Jorge Oldan, Bennett Chin, and Andrew J. Armstrong. “Exploring the Clinical Benefit of Docetaxel or Enzalutamide After Disease Progression During Abiraterone Acetate and Prednisone Treatment in Men With Metastatic Castration-Resistant Prostate Cancer.” Clin Genitourin Cancer 13, no. 4 (August 2015): 392–99. https://doi.org/10.1016/j.clgc.2015.01.004.Full Text Link to Item
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Armstrong, Andrew J. “Docetaxel for advanced prostate cancer: how early to start?” Lancet Oncol 16, no. 7 (July 2015): 741–42. https://doi.org/10.1016/S1470-2045(15)00012-1.Full Text Link to Item
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Sonpavde, Guru, Christopher G. Wang, Matthew D. Galsky, William K. Oh, and Andrew J. Armstrong. “Cytotoxic chemotherapy in the contemporary management of metastatic castration-resistant prostate cancer (mCRPC).” Bju Int 116, no. 1 (July 2015): 17–29. https://doi.org/10.1111/bju.12867.Full Text Link to Item
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Davis, Kristen, Sarah Wood, Emily Dill, Yuri Fesko, Rhonda L. Bitting, Michael R. Harrison, Andrew J. Armstrong, Judd W. Moul, and Daniel J. George. “Optimizing the efficiency and quality of sipuleucel-T delivery in an academic institution.” Clin J Oncol Nurs 19, no. 3 (June 2015): 297–303. https://doi.org/10.1188/15.CJON.297-303.Full Text Link to Item
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Somarelli, Jason A., Mary-Keara Boss, Jonathan I. Epstein, Andrew J. Armstrong, and Mariano A. Garcia-Blanco. “Carcinosarcomas: tumors in transition?” Histol Histopathol 30, no. 6 (June 2015): 673–87. https://doi.org/10.14670/HH-30.673.Full Text Link to Item
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Stover, J. T., R. A. Moore, K. Davis, M. R. Harrison, and A. J. Armstrong. “Reversal of PSA progression on abiraterone acetate through the administration with food in men with metastatic castration-resistant prostate cancer.” Prostate Cancer and Prostatic Diseases 18, no. 2 (June 2015): 161–66. https://doi.org/10.1038/pcan.2015.7.Full Text
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Armstrong, Andrew J. “New treatment options in castration-resistant prostate cancer.” J Natl Compr Canc Netw 13, no. 5 Suppl (May 2015): 690–93. https://doi.org/10.6004/jnccn.2015.0205.Full Text Link to Item
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Li, Jing, and Andrew J. Armstrong. “Counterpoints: Which should be used first in symptomatic metastatic castration-resistant prostate cancer, docetaxel or radium? Radium-223 is the preferred therapy in bone-predominant symptomatic metastatic castration-resistant prostate cancer.” Clin Adv Hematol Oncol 13, no. 5 (May 2015): 293–98.Link to Item
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Armstrong, Andrew J., and Susan Halabi. “Making progress on progression in metastatic prostate cancer.” J Clin Oncol 33, no. 12 (April 20, 2015): 1322–24. https://doi.org/10.1200/JCO.2014.59.4283.Full Text Link to Item
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Bitting, Rhonda L., Patrick Healy, Susan Halabi, Daniel J. George, Michael Goodin, and Andrew J. Armstrong. “Clinical phenotypes associated with circulating tumor cell enumeration in metastatic castration-resistant prostate cancer.” Urol Oncol 33, no. 3 (March 2015): 110.e1-110.e9. https://doi.org/10.1016/j.urolonc.2014.09.002.Full Text Link to Item
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Harrison, Michael R., and Andrew J. Armstrong. “Burden of disease matters when it comes to systemic therapy for prostate cancer.” European Urology 67, no. 3 (March 2015): 448–50. https://doi.org/10.1016/j.eururo.2014.02.032.Full Text
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Zhang, Tian, Jason Zhu, Daniel J. George, and Andrew J. Armstrong. “Enzalutamide versus abiraterone acetate for the treatment of men with metastatic castration-resistant prostate cancer.” Expert Opin Pharmacother 16, no. 4 (March 2015): 473–85. https://doi.org/10.1517/14656566.2015.995090.Full Text Link to Item
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Li, Jing, Simon G. Gregory, Mariano A. Garcia-Blanco, and Andrew J. Armstrong. “Using circulating tumor cells to inform on prostate cancer biology and clinical utility.” Crit Rev Clin Lab Sci 52, no. 4 (2015): 191–210. https://doi.org/10.3109/10408363.2015.1023430.Full Text Link to Item
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Shuch, Brian, Ali Amin, Andrew J. Armstrong, John N. Eble, Vincenzo Ficarra, Antonio Lopez-Beltran, Guido Martignoni, Brian I. Rini, and Alexander Kutikov. “Understanding pathologic variants of renal cell carcinoma: distilling therapeutic opportunities from biologic complexity.” Eur Urol 67, no. 1 (January 2015): 85–97. https://doi.org/10.1016/j.eururo.2014.04.029.Full Text Link to Item
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Sonpavde, Guru, Gregory R. Pond, Andrew J. Armstrong, Matthew D. Galsky, Lance Leopold, Brian A. Wood, Shaw-Ling Wang, et al. “Radiographic progression by Prostate Cancer Working Group (PCWG)-2 criteria as an intermediate endpoint for drug development in metastatic castration-resistant prostate cancer.” Bju International 114, no. 6b (December 2014): E25–31. https://doi.org/10.1111/bju.12589.Full Text
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Stewart, Suzanne B., Judd W. Moul, Thomas J. Polascik, Bridget F. Koontz, Cary N. Robertson, Stephen J. Freedland, Daniel J. George, W Robert Lee, Andrew J. Armstrong, and Lionel L. Bañez. “Does the multidisciplinary approach improve oncological outcomes in men undergoing surgical treatment for prostate cancer?” Int J Urol 21, no. 12 (December 2014): 1215–19. https://doi.org/10.1111/iju.12561.Full Text Link to Item
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Armstrong, Andrew J., Reza Kaboteh, Michael A. Carducci, Jan-Erik Damber, Walter M. Stadler, Mats Hansen, Lars Edenbrandt, et al. “Assessment of the bone scan index in a randomized placebo-controlled trial of tasquinimod in men with metastatic castration-resistant prostate cancer (mCRPC).” Urol Oncol 32, no. 8 (November 2014): 1308–16. https://doi.org/10.1016/j.urolonc.2014.08.006.Full Text Link to Item
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Armstrong, A. J. “In hormone-naive metastatic prostate cancer, should all patients now receive docetaxel? No, not yet.” Oncology (Williston Park, N.Y.) 28, no. 10 (October 1, 2014).
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Armstrong, Andrew J. “In hormone-naive metastatic prostate cancer, should all patients now receive docetaxel? No, not yet.” Oncology (Williston Park) 28, no. 10 (October 2014): 881–83.Link to Item
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Sonpavde, Guru, Gregory R. Pond, Andrew J. Armstrong, Stephen J. Clarke, Janette L. Vardy, Arnoud J. Templeton, Shaw-Ling Wang, et al. “Prognostic impact of the neutrophil-to-lymphocyte ratio in men with metastatic castration-resistant prostate cancer.” Clinical Genitourinary Cancer 12, no. 5 (October 2014): 317–24. https://doi.org/10.1016/j.clgc.2014.03.005.Full Text
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Bitting, Rhonda L., Daneen Schaeffer, Jason A. Somarelli, Mariano A. Garcia-Blanco, and Andrew J. Armstrong. “The role of epithelial plasticity in prostate cancer dissemination and treatment resistance.” Cancer Metastasis Rev 33, no. 2–3 (September 2014): 441–68. https://doi.org/10.1007/s10555-013-9483-z.Full Text Link to Item
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Halabi, S., H. Zhou, E. J. Small, N. C. Solomon, A. J. Armstrong, L. Shen, S. Oudard, O. Sartor, and J. S. de Bono. “795PA PROGNOSTIC MODEL FOR PREDICTING RADIOGRAPHIC PROGRESSION- FREE SURVIVAL (RPFS) IN METASTATIC CASTRATE-RESISTANT PROSTATE CANCER MEN TREATED WITH SECOND-LINE CHEMOTHERAPY.” Ann Oncol 25, no. suppl_4 (September 1, 2014): iv276. https://doi.org/10.1093/annonc/mdu336.43.Full Text Link to Item
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Bitting, Rhonda L., Patrick Healy, Patricia A. Creel, James Turnbull, Karla Morris, Sarah Yenser Wood, Herbert I. Hurwitz, et al. “A phase Ib study of combined VEGFR and mTOR inhibition with vatalanib and everolimus in patients with advanced renal cell carcinoma.” Clin Genitourin Cancer 12, no. 4 (August 2014): 241–50. https://doi.org/10.1016/j.clgc.2013.11.020.Full Text Link to Item
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Ware, Kathryn E., Mariano A. Garcia-Blanco, Andrew J. Armstrong, and Scott M. Dehm. “Biologic and clinical significance of androgen receptor variants in castration resistant prostate cancer.” Endocr Relat Cancer 21, no. 4 (August 2014): T87–103. https://doi.org/10.1530/ERC-13-0470.Full Text Link to Item
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Beer, Tomasz M., Andrew J. Armstrong, Dana E. Rathkopf, Yohann Loriot, Cora N. Sternberg, Celestia S. Higano, Peter Iversen, et al. “Enzalutamide in metastatic prostate cancer before chemotherapy.” N Engl J Med 371, no. 5 (July 31, 2014): 424–33. https://doi.org/10.1056/NEJMoa1405095.Full Text Link to Item
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Aggarwal, Rahul, Tian Zhang, Eric J. Small, and Andrew J. Armstrong. “Neuroendocrine prostate cancer: subtypes, biology, and clinical outcomes.” J Natl Compr Canc Netw 12, no. 5 (May 2014): 719–26. https://doi.org/10.6004/jnccn.2014.0073.Full Text Link to Item
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Mohler, James L., Philip W. Kantoff, Andrew J. Armstrong, Robert R. Bahnson, Michael Cohen, Anthony Victor D’Amico, James A. Eastham, et al. “Prostate cancer, version 2.2014.” J Natl Compr Canc Netw 12, no. 5 (May 2014): 686–718. https://doi.org/10.6004/jnccn.2014.0072.Full Text Link to Item
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Younis, Islam R., Daniel J. George, Terence J. McManus, Herbert Hurwitz, Patricia Creel, Andrew J. Armstrong, Jing Jie Yu, et al. “Clinical pharmacology of an atrasentan and docetaxel regimen in men with hormone-refractory prostate cancer.” Cancer Chemother Pharmacol 73, no. 5 (May 2014): 991–97. https://doi.org/10.1007/s00280-014-2432-x.Full Text Link to Item
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Armstrong, A. J. “Biomarkers in castration-resistant prostate cancer.” Clinical Advances in Hematology and Oncology 12, no. 2 (February 1, 2014): 115–18.
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Armstrong, Andrew J. “Biomarkers in castration-resistant prostate cancer.” Clinical Advances in Hematology & Oncology : H&O 12, no. 2 (February 2014): 115–18.
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Armstrong, Andrew J. “New treatments for men with castration-resistant prostate cancer: can we move from small steps to giant leaps?” European Urology 65, no. 2 (February 2014): 300–302. https://doi.org/10.1016/j.eururo.2013.08.059.Full Text
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Pond, Gregory R., Guru Sonpavde, Ronald de Wit, Mario A. Eisenberger, Ian F. Tannock, and Andrew J. Armstrong. “The prognostic importance of metastatic site in men with metastatic castration-resistant prostate cancer.” Eur Urol 65, no. 1 (January 2014): 3–6. https://doi.org/10.1016/j.eururo.2013.09.024.Full Text Link to Item
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Armstrong, A. J., M. Häggman, W. M. Stadler, J. R. Gingrich, V. Assikis, J. Polikoff, J. E. Damber, et al. “Long-term survival and biomarker correlates of tasquinimod efficacy in a multicenter randomized study of men with minimally symptomatic metastatic castration-resistant prostate cancer.” Clin Cancer Res 19, no. 24 (December 15, 2013): 6891–6901. https://doi.org/10.1158/1078-0432.CCR-13-1581.Full Text Link to Item
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Stoyanova, Tanya, Aaron R. Cooper, Justin M. Drake, Xian Liu, Andrew J. Armstrong, Kenneth J. Pienta, Hong Zhang, et al. “Prostate cancer originating in basal cells progresses to adenocarcinoma propagated by luminal-like cells.” Proc Natl Acad Sci U S A 110, no. 50 (December 10, 2013): 20111–16. https://doi.org/10.1073/pnas.1320565110.Full Text Link to Item
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Araujo, John C., Géralyn C. Trudel, Fred Saad, Andrew J. Armstrong, Evan Y. Yu, Joaquim Bellmunt, George Wilding, et al. “Docetaxel and dasatinib or placebo in men with metastatic castration-resistant prostate cancer (READY): a randomised, double-blind phase 3 trial.” Lancet Oncol 14, no. 13 (December 2013): 1307–16. https://doi.org/10.1016/S1470-2045(13)70479-0.Full Text Link to Item
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Armstrong, Andrew J., Tong Shen, Susan Halabi, Gabor Kemeny, Rhonda L. Bitting, Patricia Kartcheske, Elizabeth Embree, et al. “A phase II trial of temsirolimus in men with castration-resistant metastatic prostate cancer.” Clin Genitourin Cancer 11, no. 4 (December 2013): 397–406. https://doi.org/10.1016/j.clgc.2013.05.007.Full Text Link to Item
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Bitting, Rhonda L., Rengasamy Boominathan, Chandra Rao, Gabor Kemeny, Brad Foulk, Mariano A. Garcia-Blanco, Mark Connelly, and Andrew J. Armstrong. “Development of a method to isolate circulating tumor cells using mesenchymal-based capture.” Methods 64, no. 2 (December 1, 2013): 129–36. https://doi.org/10.1016/j.ymeth.2013.06.034.Full Text Link to Item
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Mohler, James L., Philip W. Kantoff, Andrew J. Armstrong, Robert R. Bahnson, Michael Cohen, Anthony Victor D’Amico, James A. Eastham, et al. “Prostate cancer, version 1.2014.” J Natl Compr Canc Netw 11, no. 12 (December 1, 2013): 1471–79. https://doi.org/10.6004/jnccn.2013.0174.Full Text Link to Item
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Schweizer, M. T., J. Lin, A. Blackford, A. Bardia, S. King, A. J. Armstrong, M. A. Rudek, S. Yegnasubramanian, and M. A. Carducci. “Pharmacodynamic study of disulfiram in men with non-metastatic recurrent prostate cancer.” Prostate Cancer and Prostatic Diseases 16, no. 4 (December 1, 2013): 357–61. https://doi.org/10.1038/pcan.2013.28.Full Text
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Schweizer, M. T., J. Lin, A. Blackford, A. Bardia, S. King, A. J. Armstrong, M. A. Rudek, S. Yegnasubramanian, and M. A. Carducci. “Pharmacodynamic study of disulfiram in men with non-metastatic recurrent prostate cancer.” Prostate Cancer Prostatic Dis 16, no. 4 (December 2013): 357–61. https://doi.org/10.1038/pcan.2013.28.Full Text Link to Item
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Halabi, Susan, Chen-Yen Lin, Eric J. Small, Andrew J. Armstrong, Ellen B. Kaplan, Daniel Petrylak, Cora N. Sternberg, et al. “Prognostic model predicting metastatic castration-resistant prostate cancer survival in men treated with second-line chemotherapy.” J Natl Cancer Inst 105, no. 22 (November 20, 2013): 1729–37. https://doi.org/10.1093/jnci/djt280.Full Text Link to Item
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Halabi, Susan, Andrew J. Armstrong, Oliver Sartor, Johann de Bono, Ellen Kaplan, Chen-Yen Lin, Nicole C. Solomon, and Eric J. Small. “Prostate-specific antigen changes as surrogate for overall survival in men with metastatic castration-resistant prostate cancer treated with second-line chemotherapy.” J Clin Oncol 31, no. 31 (November 1, 2013): 3944–50. https://doi.org/10.1200/JCO.2013.50.3201.Full Text Link to Item
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Pond, Gregory R., Andrew J. Armstrong, Matthew D. Galsky, Brian A. Wood, Lance Leopold, and Guru Sonpavde. “Efficacy of docetaxel-based chemotherapy following ketoconazole in metastatic castration-resistant prostate cancer: implications for prior therapy in clinical trials.” Urologic Oncology 31, no. 8 (November 2013): 1457–63. https://doi.org/10.1016/j.urolonc.2012.02.008.Full Text
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Zhang, Tian, and Andrew J. Armstrong. “Clinical phenotypes of castration-resistant prostate cancer.” Clin Adv Hematol Oncol 11, no. 11 (November 2013): 707–18.Link to Item
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Peppercorn, Jeffrey, Andrew Armstrong, David W. Zaas, and Daniel George. “Rationing in urologic oncology: lessons from sipuleucel-T for advanced prostate cancer.” Urologic Oncology 31, no. 7 (October 2013): 1079–84. https://doi.org/10.1016/j.urolonc.2011.12.022.Full Text
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George, Daniel J., Andrew J. Armstrong, and Michael R. Harrison. “Highlights in advanced prostate cancer from the 2013 American Urological Association Annual Meeting and the 2013 American Society of Clinical Oncology Annual Meeting: commentary.” Clin Adv Hematol Oncol 11 Suppl 14, no. 9 (September 2013): 16–22.Link to Item
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Noonan, K. L., S. North, R. L. Bitting, A. J. Armstrong, S. L. Ellard, and K. N. Chi. “Clinical activity of abiraterone acetate in patients with metastatic castration-resistant prostate cancer progressing after enzalutamide.” Ann Oncol 24, no. 7 (July 2013): 1802–7. https://doi.org/10.1093/annonc/mdt138.Full Text Link to Item
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Bitting, Rhonda L., and Andrew J. Armstrong. “Targeting the PI3K/Akt/mTOR pathway in castration-resistant prostate cancer.” Endocr Relat Cancer 20, no. 3 (June 2013): R83–99. https://doi.org/10.1530/ERC-12-0394.Full Text Link to Item
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Armstrong, Andrew J., Daniel J. George, and Susan Halabi. “Reply to M A Khattak et al.” J Clin Oncol 31, no. 7 (March 1, 2013): 972–73. https://doi.org/10.1200/JCO.2012.47.7224.Full Text Link to Item
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Clarke, J. M., and A. J. Armstrong. “Novel therapies for the treatment of advanced prostate cancer.” Curr Treat Options Oncol 14, no. 1 (March 2013): 109–26. https://doi.org/10.1007/s11864-012-0222-4.Full Text Link to Item
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Turnbull, James D., Julien Cobert, Tracy Jaffe, Michael R. Harrison, Daniel J. George, and Andrew J. Armstrong. “Activity of single-agent bevacizumab in patients with metastatic renal cell carcinoma previously treated with vascular endothelial growth factor tyrosine kinase inhibitors.” Clinical Genitourinary Cancer 11, no. 1 (March 2013): 45–50. https://doi.org/10.1016/j.clgc.2012.06.001.Full Text
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Bardia, A., A. L. Blackford, J. Lin, A. J. Armstrong, S. King, M. A. Rudek, S. T. Yegnasubramanian, and M. A. Carducci. “A prostate cancer clinical trials consortium trial of disulfiram (D) in men with nonmetastatic recurrent prostate cancer (PCa).” J Clin Oncol 31, no. 6_suppl (February 20, 2013): 219. https://doi.org/10.1200/jco.2013.31.6_suppl.219.Full Text Link to Item
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Fizazi, K., F. Saad, K. N. Chi, M. E. Taplin, C. N. Sternberg, A. J. Armstrong, M. Hirmand, D. Forer, and J. S. De Bono. “Impact of on-study corticosteroid use on efficacy and safety in the phase III AFFIRM study of enzalutamide (ENZA), an androgen receptor inhibitor.” J Clin Oncol 31, no. 6_suppl (February 20, 2013): 6. https://doi.org/10.1200/jco.2013.31.6_suppl.6.Full Text Link to Item
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Lin, C. Y., E. J. Small, A. J. Armstrong, E. B. Kaplan, D. P. Petrylak, C. N. Sternberg, L. Shen, S. Oudard, J. S. De Bono, and A. O. Sartor. “A model for predicting overall survival in men with metastatic castrate-resistant prostate cancer (CRPC) for whom first-line chemotherapy failed.” J Clin Oncol 31, no. 6_suppl (February 20, 2013): 24. https://doi.org/10.1200/jco.2013.31.6_suppl.24.Full Text Link to Item
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Trudel, G. C., F. Saad, A. J. Armstrong, E. Y. Yu, J. Bellmunt, G. Wilding, J. McCaffrey, et al. “Overall survival (OS) and safety of dasatinib/docetaxel versus docetaxel in patients with metastatic castration-resistant prostate cancer (mCRPC): Results from the randomized phase III READY trial.” J Clin Oncol 31, no. 6_suppl (February 20, 2013): LBA8. https://doi.org/10.1200/jco.2013.31.6_suppl.lba8.Full Text Link to Item
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Khazanie, P., and C. B. Granger. “Commentary.” Annals of Internal Medicine 158, no. 4 (February 19, 2013).
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Saylor, Philip J., Andrew J. Armstrong, Karim Fizazi, Stephen Freedland, Fred Saad, Matthew R. Smith, Bertrand Tombal, and Kenneth Pienta. “New and emerging therapies for bone metastases in genitourinary cancers.” Eur Urol 63, no. 2 (February 2013): 309–20. https://doi.org/10.1016/j.eururo.2012.10.007.Full Text Link to Item
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Harrison, Michael R., Terence Z. Wong, Andrew J. Armstrong, and Daniel J. George. “Radium-223 chloride: a potential new treatment for castration-resistant prostate cancer patients with metastatic bone disease.” Cancer Management and Research 5 (January 8, 2013): 1–14. https://doi.org/10.2147/cmar.s25537.Full Text
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Bitting, Rhonda L., and Andrew J. Armstrong. “Potential predictive biomarkers for individualizing treatment for men with castration-resistant prostate cancer.” Cancer J 19, no. 1 (January 2013): 25–33. https://doi.org/10.1097/PPO.0b013e31827e0b9c.Full Text Link to Item
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Whang, Young E., Andrew J. Armstrong, W Kimryn Rathmell, Paul A. Godley, William Y. Kim, Raj S. Pruthi, Eric M. Wallen, et al. “A phase II study of lapatinib, a dual EGFR and HER-2 tyrosine kinase inhibitor, in patients with castration-resistant prostate cancer.” Urol Oncol 31, no. 1 (January 2013): 82–86. https://doi.org/10.1016/j.urolonc.2010.09.018.Full Text Link to Item
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Pond, Gregory R., Andrew J. Armstrong, Brian A. Wood, Lance Leopold, Matthew D. Galsky, and Guru Sonpavde. “Ability of C-reactive protein to complement multiple prognostic classifiers in men with metastatic castration resistant prostate cancer receiving docetaxel-based chemotherapy.” Bju International 110, no. 11 Pt B (December 2012): E461–68. https://doi.org/10.1111/j.1464-410x.2012.11148.x.Full Text
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Scher, Howard I., Karim Fizazi, Fred Saad, Mary-Ellen Taplin, Cora N. Sternberg, Kurt Miller, Ronald de Wit, et al. “Increased survival with enzalutamide in prostate cancer after chemotherapy.” N Engl J Med 367, no. 13 (September 27, 2012): 1187–97. https://doi.org/10.1056/NEJMoa1207506.Full Text Link to Item
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Armstrong, Andrew J., Daniel J. George, and Susan Halabi. “Serum lactate dehydrogenase predicts for overall survival benefit in patients with metastatic renal cell carcinoma treated with inhibition of mammalian target of rapamycin.” J Clin Oncol 30, no. 27 (September 20, 2012): 3402–7. https://doi.org/10.1200/JCO.2011.40.9631.Full Text Link to Item
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Mohler, James L., Andrew J. Armstrong, Robert R. Bahnson, Barry Boston, J Erik Busby, Anthony Victor D’Amico, James A. Eastham, et al. “Prostate cancer, Version 3.2012: featured updates to the NCCN guidelines.” Journal of the National Comprehensive Cancer Network : Jnccn 10, no. 9 (September 2012): 1081–87. https://doi.org/10.6004/jnccn.2012.0114.Full Text
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Sonpavde, Guru, Gregory R. Pond, William R. Berry, Ronald de Wit, Andrew J. Armstrong, Mario A. Eisenberger, and Ian F. Tannock. “Serum alkaline phosphatase changes predict survival independent of PSA changes in men with castration-resistant prostate cancer and bone metastasis receiving chemotherapy.” Urol Oncol 30, no. 5 (September 2012): 607–13. https://doi.org/10.1016/j.urolonc.2010.07.002.Full Text Link to Item
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Armstrong, A. J. “Where does abiraterone fit into the metastatic prostate cancer treatment algorithm?” Community Oncology 9, no. 8 (August 1, 2012): 238–39. https://doi.org/10.1016/j.cmonc.2012.07.006.Full Text
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Sonpavde, Guru, and Andrew J. Armstrong. “Objective evaluation of bone metastases in prostate cancer: to what end?” Eur Urol 62, no. 1 (July 2012): 85–87. https://doi.org/10.1016/j.eururo.2012.02.021.Full Text Link to Item
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Armstrong, Andrew J. “The STAMPEDE trial and celecoxib: how to adapt?” The Lancet. Oncology 13, no. 5 (May 2012): 443–45. https://doi.org/10.1016/s1470-2045(12)70111-0.Full Text
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Sandilos, Joanna K., Yu-Hsin Chiu, Faraaz B. Chekeni, Allison J. Armstrong, Scott F. Walk, Kodi S. Ravichandran, and Douglas A. Bayliss. “Pannexin 1, an ATP release channel, is activated by caspase cleavage of its pore-associated C-terminal autoinhibitory region.” J Biol Chem 287, no. 14 (March 30, 2012): 11303–11. https://doi.org/10.1074/jbc.M111.323378.Full Text Link to Item
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Armstrong, Andrew J., Mario A. Eisenberger, Susan Halabi, Stephane Oudard, David M. Nanus, Daniel P. Petrylak, A Oliver Sartor, and Howard I. Scher. “Biomarkers in the management and treatment of men with metastatic castration-resistant prostate cancer.” Eur Urol 61, no. 3 (March 2012): 549–59. https://doi.org/10.1016/j.eururo.2011.11.009.Full Text Link to Item
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Armstrong, A. J., J. D. Turnbull, J. Cobert, T. Jaffe, M. R. Harrison, and D. J. George. “Activity of single-agent bevacizumab (B) in patients with metastatic renal cell carcinoma (RCC) previously treated with VEGF- and mTOR-based therapies.” J Clin Oncol 30, no. 5_suppl (February 10, 2012): 435. https://doi.org/10.1200/jco.2012.30.5_suppl.435.Full Text Link to Item
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Armstrong, A. J., J. D. Turnbull, J. Cobert, T. Jaffe, M. R. Harrison, and D. J. George. “Activity of single-agent bevacizumab (B) in patients with metastatic renal cell carcinoma (RCC) previously treated with VEGF- and mTOR-based therapies.” J Clin Oncol 30, no. 5_suppl (February 10, 2012): 435.Link to Item
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Hussain, M., D. E. Rathkopf, G. Liu, A. J. Armstrong, W. K. Kelly, A. C. Ferrari, J. D. Hainsworth, L. Yang, J. D. Schwartz, and C. S. Higano. “A phase II randomized study of cixutumumab (IMC-A12: CIX) or ramucirumab (IMC-1121B: RAM) plus mitoxantrone (M) and prednisone (P) in patients (pts) with metastatic castrate-resistant prostate cancer (mCRPC) following disease progression (PD) on docetaxel (DCT) therapy.” J Clin Oncol 30, no. 5_suppl (February 10, 2012): 97.Link to Item
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Hussain, M., D. E. Rathkopf, G. Liu, A. J. Armstrong, W. K. Kelly, A. C. Ferrari, J. D. Hainsworth, L. Yang, J. D. Schwartz, and C. S. Higano. “A phase II randomized study of cixutumumab (IMC-A12: CIX) or ramucirumab (IMC-1121B: RAM) plus mitoxantrone (M) and prednisone (P) in patients (pts) with metastatic castrate-resistant prostate cancer (mCRPC) following disease progression (PD) on docetaxel (DCT) therapy.” J Clin Oncol 30, no. 5_suppl (February 10, 2012): 97. https://doi.org/10.1200/jco.2012.30.5_suppl.97.Full Text Link to Item
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Hussain, Maha, Dana E. Rathkopf, Glenn Liu, Andrew J. Armstrong, William Kevin Kelly, Anna C. Ferrari, John D. Hainsworth, Ling Yang, Jonathan D. Schwartz, and Celestia S. Higano. “A phase II randomized study of cixutumumab (IMC-A12: CIX) or ramucirumab (IMC-1121B: RAM) plus mitoxantrone (M) and prednisone (P) in patients (pts) with metastatic castrate-resistant prostate cancer (mCRPC) following disease progression (PD) on docetaxel (DCT) therapy.” Journal of Clinical Oncology 30, no. 5 (February 10, 2012). https://doi.org/10.1200/jco.2012.30.5_suppl.97.Full Text Link to Item
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Pond, G. R., A. J. Armstrong, B. A. Wood, L. H. Leopold, M. D. Galsky, and G. Sonpavde. “Efficacy of docetaxel and prednisone in men with metastatic castration-resistant prostate cancer (mCRPC) exposed to prior ketoconazole (KC).” J Clin Oncol 30, no. 5_suppl (February 10, 2012): 204.Link to Item
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Pond, G. R., A. J. Armstrong, B. A. Wood, L. H. Leopold, M. D. Galsky, and G. Sonpavde. “Efficacy of docetaxel and prednisone in men with metastatic castration-resistant prostate cancer (mCRPC) exposed to prior ketoconazole (KC).” J Clin Oncol 30, no. 5_suppl (February 10, 2012): 204. https://doi.org/10.1200/jco.2012.30.5_suppl.204.Full Text Link to Item
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Pond, Gregory Russell, Andrew J. Armstrong, Brian A. Wood, Lance Howard Leopold, Matt D. Galsky, and Guru Sonpavde. “Efficacy of docetaxel and prednisone in men with metastatic castration-resistant prostate cancer (mCRPC) exposed to prior ketoconazole (KC).” Journal of Clinical Oncology 30, no. 5 (February 10, 2012). https://doi.org/10.1200/jco.2012.30.5_suppl.204.Full Text Link to Item
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Armstrong, A. J., J. R. Gingrich, M. Haggman, W. M. Stadler, J. E. Damber, L. Belkoff, R. Clark, et al. “Long term safety and efficacy in a randomized multicenter international phase II study of tasquinimod in chemotherapy naive patients with metastatic castrate-resistant prostate cancer.” European Urology Supplements 11, no. 1 (February 1, 2012): E126-U515.Link to Item
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Pond, Gregory R., Andrew J. Armstrong, Brian A. Wood, Melissa Brookes, Lance Leopold, William R. Berry, Ronald de Wit, Mario A. Eisenberger, Ian F. Tannock, and Guru Sonpavde. “Evaluating the value of number of cycles of docetaxel and prednisone in men with metastatic castration-resistant prostate cancer.” Eur Urol 61, no. 2 (February 2012): 363–69. https://doi.org/10.1016/j.eururo.2011.06.034.Full Text Link to Item
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Sonpavde, G., G. R. Pond, and A. J. Armstrong. “Reply to YiJun Shen and DingWei Ye's letter to the Editor re: Gregory R. Pond, Andrew J. Armstrong, Brian A. Wood, et al. Evaluating the value of number of cycles of docetaxel and prednisone in men with metastatic castration-resistant prostate cancer. Eur Urol 2012;61:363-9.” European Urology 61, no. 2 (February 1, 2012). https://doi.org/10.1016/j.eururo.2011.07.055.Full Text
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Araujo, John C., Paul Mathew, Andrew J. Armstrong, Edward L. Braud, Edwin Posadas, Mathew Lonberg, Gary E. Gallick, et al. “Dasatinib combined with docetaxel for castration-resistant prostate cancer: results from a phase 1-2 study.” Cancer 118, no. 1 (January 2012): 63–71. https://doi.org/10.1002/cncr.26204.Full Text
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Armstrong, A. J., J. W. Moul, and D. J. George. “What to order from the prostate cancer treatment menu?” Oncology (Williston Park, N.Y.) 26, no. 1 (January 1, 2012).
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Bitting, Rhonda L., and Andrew J. Armstrong. “Prognostic, predictive, and surrogate factors for individualizing treatment for men with castration-resistant prostate cancer.” Am Soc Clin Oncol Educ Book, 2012, 292–97. https://doi.org/10.14694/EdBook_AM.2012.32.24.Full Text Link to Item
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Stewart, Suzanne Biehn, Lionel L. Bañez, Cary N. Robertson, Stephen J. Freedland, Thomas J. Polascik, Donghua Xie, Bridget F. Koontz, et al. “Utilization trends at a multidisciplinary prostate cancer clinic: initial 5-year experience from the Duke Prostate Center.” J Urol 187, no. 1 (January 2012): 103–8. https://doi.org/10.1016/j.juro.2011.09.040.Full Text Link to Item
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Armstrong, A. J. “Clinical update: Epithelial-mesenchymal transition in cancer progression.” Clinical Advances in Hematology and Oncology 9, no. 12 (December 1, 2011): 941–43.
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Armstrong, Andrew J. “Epithelial-mesenchymal transition in cancer progression.” Clin Adv Hematol Oncol 9, no. 12 (December 2011): 941–43.Link to Item
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Armstrong, Andrew J., Anna C. Ferrari, and David I. Quinn. “The role of surrogate markers in the management of men with metastatic castration-resistant prostate cancer.” Clin Adv Hematol Oncol 9, no. 12 Suppl 28 (December 2011): 1–14.Link to Item
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Pili, Roberto, Michael Häggman, Walter M. Stadler, Jeffrey R. Gingrich, Vasileios J. Assikis, Anders Björk, Orjan Nordle, Goran Forsberg, Michael A. Carducci, and Andrew J. Armstrong. “Phase II randomized, double-blind, placebo-controlled study of tasquinimod in men with minimally symptomatic metastatic castrate-resistant prostate cancer.” J Clin Oncol 29, no. 30 (October 20, 2011): 4022–28. https://doi.org/10.1200/JCO.2011.35.6295.Full Text Link to Item
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Antonarakis, E. S., and A. J. Armstrong. “Evolving standards in the treatment of docetaxel-refractory castration-resistant prostate cancer.” Prostate Cancer Prostatic Dis 14, no. 3 (September 2011): 192–205. https://doi.org/10.1038/pcan.2011.23.Full Text Link to Item
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Antonarakis, E. S., and A. J. Armstrong. “Emerging therapeutic approaches in the management of metastatic castration-resistant prostate cancer.” Prostate Cancer Prostatic Dis 14, no. 3 (September 2011): 206–18. https://doi.org/10.1038/pcan.2011.24.Full Text Link to Item
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Sonpavde, Guru, Gregory R. Pond, William R. Berry, Ronald de Wit, Mario A. Eisenberger, Ian F. Tannock, and Andrew J. Armstrong. “The association between radiographic response and overall survival in men with metastatic castration-resistant prostate cancer receiving chemotherapy.” Cancer 117, no. 17 (September 1, 2011): 3963–71. https://doi.org/10.1002/cncr.25982.Full Text Link to Item
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Armstrong, Andrew J., Matthew S. Marengo, Sebastian Oltean, Gabor Kemeny, Rhonda L. Bitting, James D. Turnbull, Christina I. Herold, Paul K. Marcom, Daniel J. George, and Mariano A. Garcia-Blanco. “Circulating tumor cells from patients with advanced prostate and breast cancer display both epithelial and mesenchymal markers.” Mol Cancer Res 9, no. 8 (August 2011): 997–1007. https://doi.org/10.1158/1541-7786.MCR-10-0490.Full Text Link to Item
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Bitting, Rhonda L., John Madden, and Andrew J. Armstrong. “Therapy for non-clear cell histologies in renal cancer.” Curr Clin Pharmacol 6, no. 3 (August 2011): 169–80. https://doi.org/10.2174/157488411797189460.Full Text Link to Item
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Fleming, M. T., G. R. Pond, A. J. Armstrong, B. A. Wood, M. Brookes, L. H. Leopold, V. B. Matveev, J. M. Burke, J. R. Caton, and G. Sonpavde. “Ability of serum alkaline phosphatase (ALP) changes to complement PSA changes and predict survival in men with metastatic castration-resistant prostate cancer (mCRPC) receiving docetaxel and prednisone (DP).” Journal of Clinical Oncology 29, no. 15_suppl (May 20, 2011): e15019–e15019. https://doi.org/10.1200/jco.2011.29.15_suppl.e15019.Full Text
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Fleming, M. T., G. R. Pond, A. J. Armstrong, B. A. Wood, M. Brookes, L. H. Leopold, V. B. Matveev, J. M. Burke, J. R. Caton, and G. Sonpavde. “Ability of serum alkaline phosphatase (ALP) changes to complement PSA changes and predict survival in men with metastatic castration-resistant prostate cancer (mCRPC) receiving docetaxel and prednisone (DP).” J Clin Oncol 29, no. 15_suppl (May 20, 2011): e15019.Link to Item
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George, D. J., S. Halabi, A. J. Zurita, P. Creel, K. Mundy, J. D. Turnbull, S. E. Yenser Wood, et al. “Investigator-initiated pilot study of sunitinib malate in patients with newly diagnosed prostate cancer prior to prostatectomy: A trial of the DoD/PCF Prostate Cancer Clinical Trials Consortium.” J Clin Oncol 29, no. 15_suppl (May 20, 2011): 4664.Link to Item
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Pond, G. R., A. J. Armstrong, B. A. Wood, M. Brookes, L. H. Leopold, W. R. Berry, R. De Wit, M. A. Eisenberger, I. Tannock, and G. Sonpavde. “Evaluating the value of continuing docetaxel and prednisone (DP) beyond 10 cycles in men with metastatic castration-resistant prostate cancer (mCRPC).” Journal of Clinical Oncology 29, no. 15_suppl (May 20, 2011): 4582–4582. https://doi.org/10.1200/jco.2011.29.15_suppl.4582.Full Text
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Pond, G. R., A. J. Armstrong, B. A. Wood, M. Brookes, L. H. Leopold, W. R. Berry, R. De Wit, M. A. Eisenberger, I. Tannock, and G. Sonpavde. “Evaluating the value of continuing docetaxel and prednisone (DP) beyond 10 cycles in men with metastatic castration-resistant prostate cancer (mCRPC).” J Clin Oncol 29, no. 15_suppl (May 20, 2011): 4582.Link to Item
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Armstrong, A. J., M. Haggman, W. M. Stadler, J. R. Gingrich, V. J. Assikis, O. Nordle, G. Forsberg, M. A. Carducci, and R. Pili. “Phase II study of tasquinimod in chemotherapy-naive patients with metastatic castrate-resistant prostate cancer (CRPC): Safety and efficacy analysis including subgroups.” Journal of Clinical Oncology 29, no. 7_suppl (March 1, 2011): 126–126. https://doi.org/10.1200/jco.2011.29.7_suppl.126.Full Text
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Armstrong, A. J., M. Haggman, W. M. Stadler, J. R. Gingrich, V. J. Assikis, O. Nordle, G. Forsberg, M. A. Carducci, and R. Pili. “Phase II study of tasquinimod in chemotherapy-naive patients with metastatic castrate-resistant prostate cancer (CRPC): Safety and efficacy analysis including subgroups.” J Clin Oncol 29, no. 7_suppl (March 2011): 126.Link to Item
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Armstrong, Andrew J., Stephen J. Freedland, and Mariano Garcia-Blanco. “Epithelial-mesenchymal transition in prostate cancer: providing new targets for therapy.” Asian Journal of Andrology 13, no. 2 (March 2011): 179–80. https://doi.org/10.1038/aja.2010.169.Full Text
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Pond, G. R., A. J. Armstrong, B. A. Wood, M. Brookes, L. H. Leopold, J. M. Burke, J. R. Caton, M. T. Fleming, and G. Sonpavde. “Assessment of two prognostic risk group methods to predict outcomes with docetaxel-based therapy in men with metastatic castration-resistant prostate cancer (mCRPC).” Journal of Clinical Oncology 29, no. 7_suppl (March 1, 2011): 185–185. https://doi.org/10.1200/jco.2011.29.7_suppl.185.Full Text
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Pond, G. R., A. J. Armstrong, B. A. Wood, M. Brookes, L. H. Leopold, J. M. Burke, J. R. Caton, M. T. Fleming, and G. Sonpavde. “Assessment of two prognostic risk group methods to predict outcomes with docetaxel-based therapy in men with metastatic castration-resistant prostate cancer (mCRPC).” J Clin Oncol 29, no. 7_suppl (March 2011): 185.Link to Item
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Sonpavde, G., G. R. Pond, W. R. Berry, R. De Wit, M. A. Eisenberger, I. Tannock, and A. J. Armstrong. “Association between radiographic response and overall survival in men with metastatic castration-resistant prostate cancer receiving chemotherapy.” Journal of Clinical Oncology 29, no. 7_suppl (March 1, 2011): 118–118. https://doi.org/10.1200/jco.2011.29.7_suppl.118.Full Text
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Sonpavde, G., G. R. Pond, W. R. Berry, R. De Wit, M. A. Eisenberger, I. Tannock, and A. J. Armstrong. “Association between radiographic response and overall survival in men with metastatic castration-resistant prostate cancer receiving chemotherapy.” J Clin Oncol 29, no. 7_suppl (March 2011): 118.Link to Item
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Armstrong, A. J. “Radiotherapy aids survival in clinically staged, node+ prostate Ca: Commentary.” Oncology Report, no. JANUARY (January 1, 2011).
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Armstrong, A. J. “RT mode has an impact on pelvic fracture risk in older patients: Commentary.” Oncology Report, no. JANUARY (January 1, 2011).
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Bitting, Rhonda L., Andrew J. Armstrong, and Daniel J. George. “Management Options in Advanced Prostate Cancer: What is the Role for Sipuleucel-T?” Clin Med Insights Oncol 5 (2011): 325–32. https://doi.org/10.4137/CMO.S5977.Full Text Link to Item
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Armstrong, A. J. “Metastatic CRPC survival doesn't improve with added bevacizumab: Comment.” Oncology Report, no. JULY-AUGUST (July 1, 2010).
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Armstrong, A. J. “Denosumab prevents or stalls skeletal events in prostate cancer: Comment.” Oncology Report, no. JULY-AUGUST (July 1, 2010).
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Armstrong, A. J., and D. J. George. “Optimizing the use of docetaxel in men with castration-resistant metastatic prostate cancer.” Prostate Cancer Prostatic Dis 13, no. 2 (June 2010): 108–16. https://doi.org/10.1038/pcan.2009.62.Full Text Link to Item
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Armstrong, Andrew J., George J. Netto, Michelle A. Rudek, Susan Halabi, David P. Wood, Patricia A. Creel, Kelly Mundy, et al. “A pharmacodynamic study of rapamycin in men with intermediate- to high-risk localized prostate cancer.” Clin Cancer Res 16, no. 11 (June 1, 2010): 3057–66. https://doi.org/10.1158/1078-0432.CCR-10-0124.Full Text Link to Item
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Armstrong, A. J. “Cabazitaxel prolongs survival in late metastatic CRPC: Commentary.” Oncology Report, no. MARCH-APRIL (May 20, 2010).
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Armstrong, A. J. “IMPACT update: Survival benefit of sipuleucel-T is durable: Commentary.” Oncology Report, no. MARCH-APRIL (May 20, 2010).
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Armstrong, A. J., D. J. George, and S. Halabi. “Serum lactate dehydrogenase (LDH) as a biomarker for survival with mTor inhibition in patients with metastatic renal cell carcinoma (RCC).” Journal of Clinical Oncology 28, no. 15 (May 20, 2010).Link to Item
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Armstrong, A. J., G. Kemeny, J. D. Turnbull, C. Chao, C. Winters, Y. A. Fesko, D. A. Bradley, S. Halabi, D. J. George, and M. Garcia-Blanco. “Impact of temsirolimus and anti-androgen therapy on circulating tumor cell (CTC) biology in men with castration-resistant metastatic prostate cancer (CRPC): A phase II study.” Journal of Clinical Oncology 28, no. 15_suppl (May 20, 2010): TPS249–TPS249. https://doi.org/10.1200/jco.2010.28.15_suppl.tps249.Full Text
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Pili, R., M. Haggman, W. M. Stadler, J. R. Gingrich, V. J. Assikis, A. Bjork, G. Forsberg, M. A. Carducci, and A. J. Armstrong. “A randomized, multicenter, international phase II study of tasquinimod in chemotherapy naive patients with metastatic castrate-resistant prostate cancer (CRPC).” Journal of Clinical Oncology 28, no. 15 (May 20, 2010).Link to Item
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Pond, G. R., G. Sonpavde, W. R. Berry, R. De Wit, A. J. Armstrong, M. A. Eisenberger, and I. Tannock. “Use of changes in serum alkaline phosphatase to predict survival independent of PSA changes in men with castration-resistant prostate cancer and bone metastasis receiving chemotherapy: A retrospective analysis of the TAX327 trial.” Journal of Clinical Oncology 28, no. 15_suppl (May 20, 2010): 4637–4637. https://doi.org/10.1200/jco.2010.28.15_suppl.4637.Full Text
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Sankhala, K. K., E. G. Chiorean, A. J. Armstrong, M. J. Borad, A. M. Traynor, S. M. Gadgeel, V. K. Langmuir, C. Eng, S. Kroll, and H. Burris. “Phase I/II study of TH-302 in combination with docetaxel in patients with solid tumors including NSCLC and castrate-resistant prostate cancer (CRPC).” Journal of Clinical Oncology 28, no. 15_suppl (May 20, 2010): e13527–e13527. https://doi.org/10.1200/jco.2010.28.15_suppl.e13527.Full Text
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Turnbull, J. D., A. J. Armstrong, K. Morris, SE Yenser Wood, S. Voyles, Y. A. Fesko, and D. J. George. “A single arm phase Ib study of RAD001 and sunitinib in patients with advanced renal cell carcinoma (RCC).” Journal of Clinical Oncology 28, no. 15 (May 20, 2010).Link to Item
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Armstrong, Andrew J., Ian F. Tannock, Ronald de Wit, Daniel J. George, Mario Eisenberger, and Susan Halabi. “The development of risk groups in men with metastatic castration-resistant prostate cancer based on risk factors for PSA decline and survival.” Eur J Cancer 46, no. 3 (February 2010): 517–25. https://doi.org/10.1016/j.ejca.2009.11.007.Full Text Link to Item
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Armstrong, Allison J., Abraham K. Gebre, John S. Parks, and Catherine C. Hedrick. “ATP-binding cassette transporter G1 negatively regulates thymocyte and peripheral lymphocyte proliferation.” J Immunol 184, no. 1 (January 1, 2010): 173–83. https://doi.org/10.4049/jimmunol.0902372.Full Text Link to Item
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Armstrong, Andrew J., Elizabeth Garrett-Mayer, Ronald de Wit, Ian Tannock, and Mario Eisenberger. “Prediction of survival following first-line chemotherapy in men with castration-resistant metastatic prostate cancer.” Clin Cancer Res 16, no. 1 (January 1, 2010): 203–11. https://doi.org/10.1158/1078-0432.CCR-09-2514.Full Text Link to Item
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Armstrong, A. J. “TroVax vaccine delivers mixed results in renal cell carcinoma: Commentary.” Oncology Report, no. WINT (December 1, 2009).
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Armstrong, A. J. “Bevacizumab increases toxicity, VTE in bladder cancer: Commentary.” Oncology Report, no. FALL (September 1, 2009).
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Armstrong, A. J. “Second vaccine shows improved survival in prostate cancer: Commentary.” Oncology Report, no. FALL (September 1, 2009).
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Armstrong, Andrew J., and Phillip G. Febbo. “Using surrogate biomarkers to predict clinical benefit in men with castration-resistant prostate cancer: an update and review of the literature.” Oncologist 14, no. 8 (August 2009): 816–27. https://doi.org/10.1634/theoncologist.2009-0043.Full Text Link to Item
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Araujo, J., A. J. Armstrong, E. L. Braud, E. Posadas, M. Lonberg, G. E. Gallick, G. C. Trudel, P. Paliwal, S. Agrawal, and C. J. Logothetis. “Dasatinib and docetaxel combination treatment for patients with castration-resistant progressive prostate cancer: A phase I/II study (CA180086).” J Clin Oncol 27, no. 15_suppl (May 20, 2009): 5061.Link to Item
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Armstrong, A. J., S. Halabi, I. F. Tannock, D. J. George, R. DeWit, and M. Eisenberger. “Development of risk groups in metastatic castration-resistant prostate cancer (mCRPC) to facilitate the identification of active chemotherapy regimens.” J Clin Oncol 27, no. 15_suppl (May 20, 2009): 5137.Link to Item
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Armstrong, A. J., S. Halabi, R. de Wit, I. F. Tannock, and M. Eisenberger. “The relationship of body mass index and serum testosterone with disease outcomes in men with castration-resistant metastatic prostate cancer.” Prostate Cancer Prostatic Dis 12, no. 1 (2009): 88–93. https://doi.org/10.1038/pcan.2008.36.Full Text Link to Item
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Armstrong, Andrew J., Patricia Creel, James Turnbull, Cassandra Moore, Tracy A. Jaffe, Sherri Haley, William Petros, et al. “A phase I-II study of docetaxel and atrasentan in men with castration-resistant metastatic prostate cancer.” Clin Cancer Res 14, no. 19 (October 1, 2008): 6270–76. https://doi.org/10.1158/1078-0432.CCR-08-1085.Full Text Link to Item
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Armstrong, A. J. “Abiraterone acetate active in castration-resistant trials: Commentary.” Oncology Report, no. FALL (September 1, 2008).
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Armstrong, A. J. “Thalidomide prolongs PFS following androgen failure: Commentary.” Oncology Report, no. FALL (September 1, 2008).
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Figlin, Robert A., Elizabeth Brown, Andrew J. Armstrong, Wallace Akerley, Al B. Benson, Harold J. Burstein, David S. Ettinger, et al. “NCCN Task Force Report: mTOR inhibition in solid tumors.” J Natl Compr Canc Netw 6 Suppl 5 (September 2008): S1-20.Link to Item
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Armstrong, Andrew J., and Daniel J. George. “New drug development in metastatic prostate cancer.” Urol Oncol 26, no. 4 (July 2008): 430–37. https://doi.org/10.1016/j.urolonc.2007.11.006.Full Text Link to Item
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Armstrong, A. J., S. Halabi, I. F. Tannock, D. Ronald, and M. A. Eisenberger. “The relationship of body mass index and serum testosterone with disease outcomes in men with castration-resistant metastatic prostate cancer.” Journal of Clinical Oncology 26, no. 15_suppl (May 20, 2008): 5074–5074. https://doi.org/10.1200/jco.2008.26.15_suppl.5074.Full Text
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Whang, Y. E., C. N. Moore, A. J. Armstrong, W. K. Rathmell, P. A. Godley, J. M. Crane, G. I. Grigson, K. Morris, C. P. Watkins, and D. J. George. “A phase II trial of lapatinib in hormone refractory prostate cancer.” Journal of Clinical Oncology 26, no. 15 (May 20, 2008).Link to Item
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Armstrong, Andrew J., Elizabeth L. Garrett-Mayer, and Mario Eisenberger. “Re: Adaptive therapy for androgen-independent prostate cancer: a randomized selection trial of four regimens.” J Natl Cancer Inst 100, no. 9 (May 7, 2008): 681–82. https://doi.org/10.1093/jnci/djn104.Full Text Link to Item
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Ramiah, Veshana, Daniel J. George, and Andrew J. Armstrong. “Clinical endpoints for drug development in prostate cancer.” Curr Opin Urol 18, no. 3 (May 2008): 303–8. https://doi.org/10.1097/MOU.0b013e3282fb7807.Full Text Link to Item
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Chen, Franklin L., Andrew J. Armstrong, and Daniel J. George. “Cell signaling modifiers in prostate cancer.” Cancer J 14, no. 1 (January 2008): 40–45. https://doi.org/10.1097/PPO.0b013e318161d40f.Full Text Link to Item
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Armstrong, A. J., E. Garrett-Mayer, M. Eisenberger, I. Tannock, and R. De Wit. “In reply [12].” Journal of Clinical Oncology 25, no. 35 (December 10, 2007): 5674. https://doi.org/10.1200/JCO.2007.14.5383.Full Text
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Armstrong, Andrew J., Elizabeth S. Garrett-Mayer, Yi-Chun Ou Yang, Ronald de Wit, Ian F. Tannock, and Mario Eisenberger. “A contemporary prognostic nomogram for men with hormone-refractory metastatic prostate cancer: a TAX327 study analysis.” Clin Cancer Res 13, no. 21 (November 1, 2007): 6396–6403. https://doi.org/10.1158/1078-0432.CCR-07-1036.Full Text Link to Item
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Armstrong, Andrew J., and Daniel J. George. “Satraplatin in the treatment of hormone-refractory metastatic prostate cancer.” Ther Clin Risk Manag 3, no. 5 (October 2007): 877–83.Link to Item
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Armstrong, Andrew J., Elizabeth Garrett-Mayer, Yi-Chun Ou Yang, Michael A. Carducci, Ian Tannock, Ronald de Wit, and Mario Eisenberger. “Prostate-specific antigen and pain surrogacy analysis in metastatic hormone-refractory prostate cancer.” J Clin Oncol 25, no. 25 (September 1, 2007): 3965–70. https://doi.org/10.1200/JCO.2007.11.4769.Full Text Link to Item
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Srinivasan, Ramaprasad, Andrew J. Armstrong, William Dahut, and Daniel J. George. “Anti-angiogenic therapy in renal cell cancer.” Bju Int 99, no. 5 Pt B (May 2007): 1296–1300. https://doi.org/10.1111/j.1464-410X.2007.06834.x.Full Text Link to Item
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Armstrong, A. J., P. G. Febbo, D. J. George, and J. Moul. “Systemic strategies for prostate cancer.” Minerva Urol Nefrol 59, no. 1 (March 2007): 11–25.Link to Item
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Mendiratta, Prateek, Andrew J. Armstrong, and Daniel J. George. “Current standard and investigational approaches to the management of hormone-refractory prostate cancer.” Rev Urol 9 Suppl 1 (2007): S9–19.Link to Item
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Armstrong, Andrew J., and Mario Eisenberger. “Does gonadotropin-releasing-hormone agonist therapy for prostate cancer increase the risk of fracture?” Nat Clin Pract Urol 3, no. 5 (May 2006): 246–47. https://doi.org/10.1038/ncpuro0462.Full Text Link to Item
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Armstrong, Andrew J., and Michael A. Carducci. “New drugs in prostate cancer.” Curr Opin Urol 16, no. 3 (May 2006): 138–45. https://doi.org/10.1097/01.mou.0000193390.69845.bb.Full Text Link to Item
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Armstrong, Andrew J., and Michael A. Carducci. “Advanced prostate cancer: the future.” Can J Urol 12 Suppl 2 (June 2005): 42–47.Link to Item
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Armstrong, Andrew J., and Michael A. Carducci. “Chemotherapy for advanced prostate cancer: results of new clinical trials and future studies.” Curr Oncol Rep 7, no. 3 (May 2005): 220–27. https://doi.org/10.1007/s11912-005-0077-y.Full Text Link to Item
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Armstrong, Andrew J., and Michael A. Carducci. “Novel therapeutic approaches to advanced prostate cancer.” Clin Adv Hematol Oncol 3, no. 4 (April 2005): 271–82.Link to Item
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Eck, S. L., and A. Armstrong. “EpCAM is an important suppressor of anti-tumor immunity [2].” Cancer Biology and Therapy 4, no. 4 (April 1, 2005).
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Armstrong, Amy J., Brian T. McMahon, Steven L. West, and Allen Lewis. “Workplace discrimination and cumulative trauma disorders: the national EEOC ADA research project.” Work 25, no. 1 (2005): 49–56.Link to Item
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Armstrong, Andrew, and Stephen L. Eck. “EpCAM: A new therapeutic target for an old cancer antigen.” Cancer Biol Ther 2, no. 4 (July 2003): 320–26. https://doi.org/10.4161/cbt.2.4.451.Full Text Link to Item
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Nightingale, R. W., D. L. Camacho, A. J. Armstrong, J. J. Robinette, and B. S. Myers. “Inertial properties and loading rates affect buckling modes and injury mechanisms in the cervical spine.” J Biomech 33, no. 2 (February 2000): 191–97. https://doi.org/10.1016/s0021-9290(99)00156-6.Full Text Link to Item
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Nightingale, R. W., A. J. Armstrong, D. L. Camacho, and B. S. Myers. “Cervical spine buckling: The effects of vertebral mass and loading rate.” American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed 36 (1997): 231–32.
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Fukasawa, K., R. Zhou, W. T. Matten, A. J. Armstrong, I. Daar, M. Oskarsson, B. K. Sathyanarayana, L. Maclvor, T. G. Wood, and G. F. Vande Woude. “Mutagenic analysis of functional domains of the mos proto-oncogene and identification of the sites important for MAPK activation and DNA binding.” Oncogene 11, no. 8 (October 1995): 1447–57.
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Bevan, T. D., A. J. Manninen, J. B. Cook, A. J. Armstrong, J. R. Hook, and H. E. Hall. “Vortex Mutual Friction in Rotating Superfluid 3He-B.” Phys Rev Lett 74, no. 5 (January 30, 1995): 750–53. https://doi.org/10.1103/PhysRevLett.74.750.Full Text Link to Item
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Mullins, T. R., V. V. Dmitriev, A. J. Armstrong, A. J. Manninen, J. R. Hook, and H. E. Hall. “Identification of the order parameter of 3He-A using low-field NMR measurements.” Phys Rev Lett 72, no. 26 (June 27, 1994): 4117–20. https://doi.org/10.1103/PhysRevLett.72.4117.Full Text Link to Item
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Tang, Y., A. J. Armstrong, R. C. Mockler, and W. J. O’Sullivan. “Free-expansion melting of a colloidal monolayer.” Phys Rev Lett 62, no. 20 (May 15, 1989): 2401–4. https://doi.org/10.1103/PhysRevLett.62.2401.Full Text Link to Item
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Bender, D. A., A. J. Armstrong, C. R. Monkhouse, and J. P. Richardson. “Changes in pancreatic tryptophan in the rat in response to fasting. The effect of B-cytotoxic agents and variation through the oestrous cycle.” Pflugers Arch 356, no. 3 (1975): 245–51. https://doi.org/10.1007/BF00583836.Full Text Link to Item
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Kinsey, Emily N., Tian Zhang, and Andrew J. Armstrong. “Metastatic Hormone-Sensitive Prostate Cancer: A Review of the Current Treatment Landscape.” Cancer J 26, no. 1 (n.d.): 64–75. https://doi.org/10.1097/PPO.0000000000000418.Full Text Link to Item
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Book Sections
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Li, J., and A. J. Armstrong. “Prognostic and predictive biomarkers for castration resistant prostate cancer.” In Biomarkers in Disease: Methods, Discoveries and Applications: Biomarkers in Cancer, 447–80, 2015. https://doi.org/10.1007/978-94-007-7681-4_13.Full Text
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Armstrong, A. J., and M. A. Carducci. “Chemotherapy for advanced prostate cancer.” In Treatment Methods for Early and Advanced Prostate Cancer, 327–39, 2008.
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Armstrong, A. J., and M. A. Carducci. “Chemotherapy for advanced prostate cancer.” In Prostate Cancer: Principles and Practice, 989–1003, 2005.
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Other Articles
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Somarelli, Jason A., Daneen Schaeffer, Mathew S. Marengo, Tristan Bepler, Douglas Rouse, Anne F. Buckley, Jonathan I. Epstein, Andrew J. Armstrong, and Mariano A. Garcia-Blanco. “Abstract SS02-02: A long walk from FGFR2 alternative splicing to cancer progression.” Cell, Molecular, and Tumor Biology. American Association for Cancer Research, November 2014. https://doi.org/10.1158/1538-7755.disp13-ss02-02.Full Text
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Armstrong, Andrew J., Judd W. Moul, and Daniel J. George. “What to order from the prostate cancer treatment menu?” Oncology (Williston Park), January 2012.Link to Item
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Armstrong, Andrew J., Judd W. Moul, and Daniel J. George. “What to Order From the Prostate Cancer Treatment Menu? THE CRAWFORD/FLAIG ARTICLE REVIEWED.” Oncology New York, January 2012.Link to Item
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Conference Papers
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Shah, Anand, Thomas J. Polascik, Daniel J. George, John Anderson, Terry Hyslop, Alicia M. Ellis, Andrew J. Armstrong, et al. “Implementation and Impact of a Risk-Stratified Prostate Cancer Screening Algorithm as a Clinical Decision Support Tool in a Primary Care Network.” In J Gen Intern Med, 36:92–99, 2021. https://doi.org/10.1007/s11606-020-06124-2.Full Text Link to Item
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Armstrong, Andrew J., Neal D. Shore, Russell Z. Szmulewitz, Daniel P. Petrylak, Jeffrey Holzbeierlein, Arnauld Villers, Arun Azad, et al. “Efficacy of Enzalutamide plus Androgen Deprivation Therapy in Metastatic Hormone-Sensitive Prostate Cancer by Pattern of Metastatic Spread: ARCHES Post Hoc Analyses.” In The Journal of Urology, 101097JU0000000000001568, 2020. https://doi.org/10.1097/ju.0000000000001568.Full Text
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Shore, N. D., E. D. Crawford, R. Z. Szmulewitz, D. Petrylak, J. Holzbeierlein, A. Villers, A. Azad, et al. “Impact of baseline disease volume and prior docetaxel therapy on PSA-related outcomes in patients with mHSPC receiving enzalutamide plus ADT.” In Swiss Medical Weekly, 25S-26S, 2020.Link to Item
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Hong, Jun Hyuk, Arnulf Stenzl, Russell Z. Szmulewitz, Daniel Petrylak, Jeffrey Holzbeierlein, Arnauld Villers, Arun Azad, et al. “Arches - the role of androgen deprivation therapy (ADT) with enzalutamide (ENZA) or placebo (PBO) in metastatic hormone-sensitive prostate cancer (MHSPC): post hoc analyses of high and low disease volume and risk groups.” In International Journal of Urology, 27:102–3, 2020.Link to Item
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Iguchi, Taro, Yeong-Shiau Pu, Go Kimura, Seok-Soo Byun, Hong Koo Ha, Jun Hyuk Hong, Jian-Ri Li, et al. “Post hoc analysis of East Asian subpopulation in arches, a phase 3 study of androgen deprivation therapy (ADT) with enzalutamide (ENZA) or placebo (PBO) in metastatic hormone-sensitive prostate cancer (MHSPC).” In International Journal of Urology, 27:96–97, 2020.Link to Item
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Alcaraz, A., R. Z. Szmulewitz, N. Shore, E. D. Crawford, D. P. Petrylak, J. Holzbeierlein, A. Villers, et al. “635P ARCHES - The role of androgen deprivation therapy (ADT) with enzalutamide (ENZA) or placebo (PBO) in metastatic hormone-sensitive prostate cancer (mHSPC): Post hoc analyses of efficacy by baseline prostate-specific antigen (PSA) levels.” In Annals of Oncology, 31:S523–24. Elsevier BV, 2020. https://doi.org/10.1016/j.annonc.2020.08.894.Full Text
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Tombal, B. F., S. J. Freedland, A. J. Armstrong, T. M. Beer, A. Stenzl, C. N. Sternberg, M. Hussain, et al. “665P Impact of enzalutamide on patient-reported fatigue in hormone-sensitive prostate cancer (HSPC) or castration-resistant prostate cancer (CRPC).” In Annals of Oncology, 31:S536–37. Elsevier BV, 2020. https://doi.org/10.1016/j.annonc.2020.08.924.Full Text
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Patierno, Brendon M., Wayne Glover, Wen-Chi Foo, Jason A. Somarelli, Kathryn E. Ware, Lingfan Xu, Yanjing Li, et al. “Abstract A114: Characterization of a metastatic prostate cancer xenograft derived from a patient of African ancestry.” In Poster Presentations Proffered Abstracts. American Association for Cancer Research, 2020. https://doi.org/10.1158/1538-7755.disp18-a114.Full Text
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Patierno, Brendon M., Wayne Glover, Wen-Chi Foo, Jason A. Somarelli, Kathryn E. Ware, Lingfan Xu, Yanjing Li, et al. “Characterization of a metastatic prostate cancer xenograft derived from a patient of African ancestry.” In Cancer Epidemiology Biomarkers & Prevention, Vol. 29, 2020.Link to Item
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Sartor, Oliver, Andrew J. Armstrong, Chiledum Ahaghotu, David G. McLeod, Matthew R. Cooperberg, David F. Penson, Philip W. Kantoff, et al. “Abstract D084: Overall survival (OS) of African-American (AA) and Caucasian (CAU) men who received sipuleucel-T for metastatic castration-resistant prostate cancer (mCRPC)—final PROCEED analysis.” In Poster Presentations Proffered Abstracts. American Association for Cancer Research, 2020. https://doi.org/10.1158/1538-7755.disp19-d084.Full Text
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Brown, Landon Carter, Ramy Sedhom, Eric B. Schwartz, Jason Zhu, Chester Kao, Matthew D. Tucker, Matthew Labriola, et al. “Association of LRP1B pathogenic genomic alterations with favorable outcomes with immune checkpoint inhibitors across multiple tumor types.” In Journal of Clinical Oncology, Vol. 38, 2020.Link to Item
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Marshall, Catherine Handy, Jong Chul Park, Wei Fu, Hao Wang, Theodore L. DeWeese, Serina King, Michaella Afful, et al. “Results of the randomized phase II study of sipuleucel-T (Sip-T) +/- Radium-223 (Ra-223) in men with bone-metastatic castration resistant prostate cancer.” In Journal of Clinical Oncology, Vol. 38, 2020.Link to Item
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Morris, Michael J., Lawrence Fong, Daniel Peter Petrylak, A Oliver Sartor, Celestia S. Higano, Lance C. Pagliaro, Ajjai Shivaram Alva, et al. “Safety and clinical activity of atezolizumab (atezo) + radium-223 dichloride (r-223) in 2L metastatic castration-resistant prostate cancer (mCRPC): Results from a phase Ib clinical trial.” In Journal of Clinical Oncology, Vol. 38, 2020.Link to Item
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Watson, Catherine, Sarah Tait, Lindsay Soo, Jennifer Kay Plichta, Tian Zhang, Edgardo Castellar, Andrew J. Armstrong, et al. “The prevalence of germline mutations among patients with solid tumors with genomic alterations identified on tumor testing: Results from a tertiary care academic center molecular tumor board.” In Journal of Clinical Oncology, Vol. 38, 2020.Link to Item
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Agarwal, Anika, Jennifer Modliszewski, Lauren Davey, Marco Reyes-Martinez, Daniella Runyambo, David Corcoran, Holly Dressman, et al. “Investigating the role of the gastrointestinal microbiome in response to immune checkpoint inhibitors (ICIs) among patients (pts) with metastatic renal cell carcinoma (mRCC).” In Journal of Clinical Oncology, Vol. 38. AMER SOC CLINICAL ONCOLOGY, 2020.Link to Item
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Armstrong, Andrew J., Jun Luo, Monika Anand, Emmanuel S. Antonarakis, David M. Nanus, Paraskevi Giannakakou, Russell Zelig Szmulewitz, et al. “AR-V7 and prediction of benefit with taxane therapy: Final analysis of PROPHECY.” In Journal of Clinical Oncology, Vol. 38. AMER SOC CLINICAL ONCOLOGY, 2020.Link to Item
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Brown, Landon Carter, Kunal Desai, Chester Kao, Emily Noelle Kinsey, Patrick Healy, Julie Kephart, Michael Roger Harrison, et al. “A multicenter retrospective study to evaluate real-world clinical outcomes in patients with metastatic renal cell carcinoma (mRCC) and brain metastasis treated with ipilimumab and nivolumab.” In Journal of Clinical Oncology, Vol. 38. AMER SOC CLINICAL ONCOLOGY, 2020.Link to Item
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Brown, Landon Carter, Susan Halabi, Joseph Schonhoft, Jun Luo, David M. Nanus, Paraskevi Giannakakou, Russell Zelig Szmulewitz, et al. “Association of circulating tumor cell chromosomal instability with worse outcomes in men with mCRPC treated with abiraterone or enzalutamide.” In Journal of Clinical Oncology, Vol. 38. AMER SOC CLINICAL ONCOLOGY, 2020.Link to Item
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Desai, Kunal, Landon Carter Brown, Wei Wei, Kimberly D. Allman, Allison Martin, Laura S. Wood, Shilpa Gupta, et al. “Multicenter retrospective analysis of patients with metastatic renal cell carcinoma (mRCC) and bone metastases treated with ipilimumab and nivolumab.” In Journal of Clinical Oncology, Vol. 38. AMER SOC CLINICAL ONCOLOGY, 2020.Link to Item
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Gupta, Santosh, Susan Halabi, Gabor Kemeny, Monika Anand, David M. Nanus, Paraskevi Giannakakou, Daniel J. George, Simon Gregory, and Andrew J. Armstrong. “Circulating tumor cell (CTC) genomic signatures of hormone therapy resistance in men with metastatic castration-resistant prostate cancer (mCRPC).” In Journal of Clinical Oncology, Vol. 38. AMER SOC CLINICAL ONCOLOGY, 2020.Link to Item
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Marshall, Catherine Handy, Jong Chul Park, Theodore L. DeWeese, Serina King, Michaella Afful, Julia Hurrelbrink, Charlotte Manogue, et al. “Randomized phase II study of sipuleucel-T (SipT) with or without radium-223 (Ra223) in men with asymptomatic bone-metastatic castrate-resistant prostate cancer (mCRPC).” In Journal of Clinical Oncology, Vol. 38. AMER SOC CLINICAL ONCOLOGY, 2020.Link to Item
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Ross, Ashley, Andrew J. Armstrong, Christopher M. Pieczonka, James L. Bailen, Ronald F. Tutrone, Matthew R. Cooperberg, Christian P. Pavlovich, et al. “A comparison of sipuleucel-T (sip-T) product parameters from two phase III studies: PROVENT in active surveillance prostate cancer and IMPACT in metastatic castrate-resistant prostate cancer (mCRPC).” In Journal of Clinical Oncology, Vol. 38. AMER SOC CLINICAL ONCOLOGY, 2020.Link to Item
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Zhang, Tian, Julie Kephart, Elizabeth Bronson, Monika Anand, Christine Daly, Ivan Spasojevic, Hannah Berg, et al. “Disulfiram (DSF) pharmacokinetics (PK) and copper PET imaging in a phase Ib study of intravenous (IV) copper loading with oral DSF for patients with metastatic castration-resistant prostate cancer (mCRPC).” In Journal of Clinical Oncology, Vol. 38. AMER SOC CLINICAL ONCOLOGY, 2020.Link to Item
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Zhang, Tian, Yuan Wu, Anika Agarwal, Mark D. Starr, Marco Reyes-Martinez, Monika Anand, Daniella Runyambo, et al. “Longitudinal multiplex cytokine analysis for patients (pts) with metastatic renalcell carcinoma (mRCC) treated with ipilimumab/nivolumab (I plus N).” In Journal of Clinical Oncology, Vol. 38. AMER SOC CLINICAL ONCOLOGY, 2020.Link to Item
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Kao, Chester, Eric Powers, Michael B. Datto, Michelle Green, Michael Roger Harrison, Andrew J. Armstrong, Daniel J. George, Jeffrey Melson Clarke, John H. Strickler, and Tian Zhang. “Tumor mutational burden (TMB) as a predictive biomarker of immune checkpoint blockade (ICB) in metastatic solid tumors.” In Journal of Clinical Oncology, Vol. 38. AMER SOC CLINICAL ONCOLOGY, 2020.Link to Item
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Schweizer, Michael T., Gavin Ha, Roman Gulati, Landon C. Brown, Rana R. McKay, Tanya Dorff, Anna C. H. Hoge, et al. “CDK12-Mutated Prostate Cancer: Clinical Outcomes With Standard Therapies and Immune Checkpoint Blockade.” In Jco Precis Oncol, 4:382–92, 2020. https://doi.org/10.1200/po.19.00383.Full Text Link to Item
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Fizazi, K., P. Gonzalez Mella, D. Castellano, N. Minatta, A Rezazadeh Kalebasty, D. Shaffer, J. C. Vazquez Limon, et al. “Efficacy and safety of nivolumab in combination with docetaxel in men with metastatic castration-resistant prostate cancer in CheckMate 9KD.” In Annals of Oncology, Vol. 30. OXFORD UNIV PRESS, 2019.Link to Item
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Stenzl, A., R. Z. Szmulewitz, D. P. Petrylak, J. Holzbeierlein, A. Villers, A. A. Azad, A. Alcaraz, et al. “ARCHES - The role of androgen deprivation therapy (ADT) with enzalutamide (ENZA) or placebo (PBO) in metastatic hormone-sensitive prostate cancer (mHSPC): Post hoc analyses of high and low disease volume and risk groups.” In Annals of Oncology, 30:332-+. OXFORD UNIV PRESS, 2019.Link to Item
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Tran, B., H. Kouros-Mehr, A. Fermin, L. Horvath, F. Roncolato, M. Rettig, T. Dorff, et al. “A phase I study of AMG 160, a half-life extended bispecific T cell engager (HLE BiTE) immuno-oncology therapy targeting PSMA, in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC).” In Annals of Oncology, 30:353–353. OXFORD UNIV PRESS, 2019.Link to Item
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Horvath, Lisa, Andrew J. Armstrong, Russell Szmulewitz, Daniel Petrylak, Arnauld Villers, Arun Azad, Antonio Alcaraz, et al. “Phase 3 Study of Androgen Deprivation Therapy (ADT) with Enzalutamide (ENZA) or Placebo (PBO) in Metastatic Hormone-Sensitive Prostate Cancer (MHSPC): The Arches Trial.” In Asia Pacific Journal of Clinical Oncology, 15:32–33. WILEY, 2019.Link to Item
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Bueren, Moritz von, Andrew J. Armstrong, Russell Szmulewitz, Daniel Petrylak, Arnauld Villers, Arun Azad, Antonio Alcaraz, et al. “Androgen deprivation therapy with enzalutamide or placebo in metastatic hormone-sensitive prostate cancer: ARCHES.” In Swiss Medical Weekly, 149:16S-16S. E M H SWISS MEDICAL PUBLISHERS LTD, 2019.Link to Item
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Armstrong, Andrew J., Russell Zelig Szmulewitz, Daniel Peter Petrylak, Jeffrey M. Holzbeierlein, Arnauld Villers, Arun Azad, Antonio Alcaraz, et al. “ARCHES: Efficacy of androgen deprivation therapy (ADT) with enzalutamide (ENZA) or placebo (PBO) in metastatic hormone-sensitive prostate cancer (mHSPC).” In Journal of Clinical Oncology, 37:5048–5048. American Society of Clinical Oncology (ASCO), 2019. https://doi.org/10.1200/jco.2019.37.15_suppl.5048.Full Text
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Autio, Karen A., Emmanuel S. Antonarakis, Raymond Baser, Mark N. Stein, Daniel H. Shevrin, Ulka N. Vaishampayan, Tina M. Mayer, et al. “Evaluation of the patient-reported outcomes common terminology criteria for adverse events (PRO-CTCAE) with abiraterone acetate plus prednisone (AAP), degarelix (D), or the combination in men with biochemically recurrent prostate cancer (BCRPC).” In Journal of Clinical Oncology, 37:5080–5080. American Society of Clinical Oncology (ASCO), 2019. https://doi.org/10.1200/jco.2019.37.15_suppl.5080.Full Text
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Chowdhury, Simon, Joaquin Mateo, Mitchell Gross, Andrew J. Armstrong, Marcia Cruz-Correa, Josep M. Piulats, Jean-Yves Blay, et al. “Pamiparib, an investigational PARP inhibitor, in patients with metastatic castration-resistant prostate cancer (mCRPC) and a circulating tumor cell (CTC) homologous recombination deficiency (HRD) phenotype or BRCA defects: A trial in progress.” In Journal of Clinical Oncology, 37:TPS5086–TPS5086. American Society of Clinical Oncology (ASCO), 2019. https://doi.org/10.1200/jco.2019.37.15_suppl.tps5086.Full Text
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Halabi, Susan, Sandipan Dutta, John C. Araujo, Christopher Logothetis, Cora N. Sternberg, Andrew J. Armstrong, Michael Anthony Carducci, et al. “External validation of a prognostic model for overall survival (OS) in men with metastatic castration-resistant prostate cancer (mCRPC).” In Journal of Clinical Oncology, 37:5022–5022. American Society of Clinical Oncology (ASCO), 2019. https://doi.org/10.1200/jco.2019.37.15_suppl.5022.Full Text
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Labriola, Matthew, Jason Zhu, Sachica Cheris, Xin Liu, Kathryn Perkinson, Zuowei Su, Shannon McCall, et al. “Concordance between PD-L1 assays for metastatic renal cell carcinoma (mRCC) and metastatic urothelial carcinoma (mUC).” In Journal of Clinical Oncology, 37:e14259–e14259. American Society of Clinical Oncology (ASCO), 2019. https://doi.org/10.1200/jco.2019.37.15_suppl.e14259.Full Text
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Mara, Alexandria, Jason Zhu, Yuan Wu, Tom Callis, Shan Yang, Edward D. Esplin, Robert L. Nussbaum, et al. “Prevalence of pathogenic germline variants in DNA repair by race, age, and ethnicity in men with prostate cancer.” In Journal of Clinical Oncology, 37:5062–5062. American Society of Clinical Oncology (ASCO), 2019. https://doi.org/10.1200/jco.2019.37.15_suppl.5062.Full Text
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Morris, Michael J., Glenn Heller, Alan Haruo Bryce, Andrew J. Armstrong, Himisha Beltran, Olwen Mary Hahn, Eric C. McGary, et al. “Alliance A031201: A phase III trial of enzalutamide (ENZ) versus enzalutamide, abiraterone, and prednisone (ENZ/AAP) for metastatic castration resistant prostate cancer (mCRPC).” In Journal of Clinical Oncology, 37:5008–5008. American Society of Clinical Oncology (ASCO), 2019. https://doi.org/10.1200/jco.2019.37.15_suppl.5008.Full Text
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Sartor, A Oliver, Andrew J. Armstrong, Chiledum Ahaghotu, David G. McLeod, Matthew R. Cooperberg, David F. Penson, Philip W. Kantoff, et al. “Overall survival (OS) of African-American (AA) and Caucasian (CAU) men who received sipuleucel-T for metastatic castration-resistant prostate cancer (mCRPC): Final PROCEED analysis.” In Journal of Clinical Oncology, 37:5035–5035. American Society of Clinical Oncology (ASCO), 2019. https://doi.org/10.1200/jco.2019.37.15_suppl.5035.Full Text
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Stenzl, Arnulf, Curtis Dunshee, Ugo De Giorgi, Boris Alekseev, Taro Iguchi, Russell Zelig Szmulewitz, Thomas W. Flaig, et al. “Health-related quality of life (HRQoL) and pain progression with enzalutamide (ENZ) in metastatic hormone-sensitive prostate cancer (mHSPC) from the ARCHES study.” In Journal of Clinical Oncology, 37:5044–5044. American Society of Clinical Oncology (ASCO), 2019. https://doi.org/10.1200/jco.2019.37.15_suppl.5044.Full Text
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Zhang, Tian, Bridget F. Koontz, Scott T. Tagawa, Himanshu Nagar, Rhonda L. Bitting, Bart Frizzell, Julia Rasmussen, et al. “A phase II Salvage Trial of AR Inhibition with ADT and Apalutamide with Radiation therapy followed by docetaxel in men with PSA recurrent prostate cancer (PC) after radical prostatectomy (STARTAR).” In Journal of Clinical Oncology, 37:TPS5097–TPS5097. American Society of Clinical Oncology (ASCO), 2019. https://doi.org/10.1200/jco.2019.37.15_suppl.tps5097.Full Text
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Zhu, Jason, Matthew D. Tucker, Chester Kao, Matthew Labriola, Sachica Cheris, Michael B. Datto, Yuan Wu, et al. “Immune checkpoint inhibitor response in tumors with LRP1B variants.” In Journal of Clinical Oncology, 37:e14291–e14291. American Society of Clinical Oncology (ASCO), 2019. https://doi.org/10.1200/jco.2019.37.15_suppl.e14291.Full Text
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Armstrong, Andrew J., Carl A. Olsson, Ian D. Schnadig, Raoul S. Concepcion, Jeffrey L. Vacirca, Ronald F. Tutrone, Shaker R. Dakhil, et al. “Real-world PROCEED registry data: Sipuleucel-T in elderly men with metastatic castration-resistant prostate cancer (mCRPC).” In Journal of Clinical Oncology, 37:177–177. American Society of Clinical Oncology (ASCO), 2019. https://doi.org/10.1200/jco.2019.37.7_suppl.177.Full Text
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Armstrong, Andrew J., Mohammed Al-Adhami, Ping Lin, Teresa Parli, Jennifer Sugg, Joyce Leta Steinberg, Bertrand F. TOMBAL, et al. “The clinical impact of bone scan (BS) flare with enzalutamide (ENZA) in men with metastatic castration-resistant prostate cancer (mCRPC).” In Journal of Clinical Oncology, 37:183–183. American Society of Clinical Oncology (ASCO), 2019. https://doi.org/10.1200/jco.2019.37.7_suppl.183.Full Text
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Armstrong, Andrew J., Rhonda L. Bitting, Patrick Healy, Daniel J. George, Sung Kim, Tina M. Mayer, Carolyn Winters, et al. “Phase II trial enzalutamide and androgen deprivation therapy (ADT) with salvage radiation in men with high-risk PSA recurrent prostate cancer (PC): The STREAM trial.” In Journal of Clinical Oncology, 37:29–29. American Society of Clinical Oncology (ASCO), 2019. https://doi.org/10.1200/jco.2019.37.7_suppl.29.Full Text
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Armstrong, Andrew J., Russell Zelig Szmulewitz, Daniel Peter Petrylak, Arnauld Villers, Arun Azad, Antonio Alcaraz, Boris Y. Alekseev, et al. “Phase III study of androgen deprivation therapy (ADT) with enzalutamide (ENZA) or placebo (PBO) in metastatic hormone-sensitive prostate cancer (mHSPC): The ARCHES trial.” In Journal of Clinical Oncology, 37:687–687. American Society of Clinical Oncology (ASCO), 2019. https://doi.org/10.1200/jco.2019.37.7_suppl.687.Full Text
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Chowdhury, Simon, Joaquin Mateo, Mitchell Gross, Andrew J. Armstrong, Marcia Cruz-Correa, Josep M. Piulats, Jean-Yves Blay, et al. “A phase II trial in progress: Pamiparib, an investigational PARP inhibitor, in patients with metastatic castration-resistant prostate cancer and a circulating tumor cell homologous recombination deficiency (HRD) phenotype or BRCA defects.” In Journal of Clinical Oncology, 37:TPS328–TPS328. American Society of Clinical Oncology (ASCO), 2019. https://doi.org/10.1200/jco.2019.37.7_suppl.tps328.Full Text
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Clarke, Noel W., Andrew J. Armstrong, Antoine Thiery-Vuillemin, Mototsugu Oya, Dingwei Ye, Joaquin Mateo, Carsten Dietrich Goessl, Jinyu Kang, Sherry Liu, and Fred Saad. “PROPEL: A randomized, phase III trial evaluating the efficacy and safety of olaparib combined with abiraterone as first-line therapy in patients with metastatic castration-resistant prostate cancer (mCRPC).” In Journal of Clinical Oncology, 37:TPS340–TPS340. American Society of Clinical Oncology (ASCO), 2019. https://doi.org/10.1200/jco.2019.37.7_suppl.tps340.Full Text
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Harrison, Michael Roger, Michel Khouri, Andrew J. Armstrong, Tian Zhang, Megan Ann McNamara, Monika Anand, Ellen Bratt, et al. “PEAX: Men with metastatic castrate-resistant prostate cancer (mCRPC) treated with either sipuleucel-T (SIP-T), enzalutamide (ENZA) or abiraterone acetate (ABI) undergoing cardiopulmonary exercise testing (CPET).” In Journal of Clinical Oncology, 37:281–281. American Society of Clinical Oncology (ASCO), 2019. https://doi.org/10.1200/jco.2019.37.7_suppl.281.Full Text
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TOMBAL, Bertrand F., Andrew J. Armstrong, Jeffrey Kent Barrus, Tomasz M. Beer, Simon Chowdhury, Christopher P. Evans, Axel Heidenreich, et al. “Adverse events of special interest assessed by review of safety data in enzalutamide castration-resistant prostate cancer (CRPC) trials.” In Journal of Clinical Oncology, 37:237–237. American Society of Clinical Oncology (ASCO), 2019. https://doi.org/10.1200/jco.2019.37.7_suppl.237.Full Text
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Tucker, Matthew D., Jason Zhu, William R. Berry, Sundhar Ramalingam, Tian Zhang, Michael Roger Harrison, Yuan Wu, Patrick Healy, Daniel J. George, and Andrew J. Armstrong. “Pembrolizumab in men with heavily treated metastatic castration-resistant prostate cancer (mCRPC).” In Journal of Clinical Oncology, 37:172–172. American Society of Clinical Oncology (ASCO), 2019. https://doi.org/10.1200/jco.2019.37.7_suppl.172.Full Text
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Vogelzang, Nicholas J., Philip W. Kantoff, Mark C. Scholz, Jeffrey L. Vacirca, Shaker R. Dakhil, Sanjay Goel, Matthew Harmon, Hong Tang, Bruce Brown, and Andrew J. Armstrong. “Experience with sipuleucel-T in metastatic castration-resistant prostate cancer (mCRPC) with visceral spread from PROCEED.” In Journal of Clinical Oncology, 37:174–174. American Society of Clinical Oncology (ASCO), 2019. https://doi.org/10.1200/jco.2019.37.7_suppl.174.Full Text
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Zhu, Jason, Matthew Labriola, Sachica Cheris, Xin Liu, Kathryn Perkinson, Zuowei Su, Shannon McCall, et al. “Concordance between PD-L1 assays for metastatic renal cell carcinoma (mRCC) and metastatic urothelial carcinoma (mUC).” In Journal of Clinical Oncology, 37:577–577. American Society of Clinical Oncology (ASCO), 2019. https://doi.org/10.1200/jco.2019.37.7_suppl.577.Full Text
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Harrison, M. R., P. G. Davis, M. G. Khouri, R. T. Gupta, A. J. Armstrong, M. A. McNamara, T. Zhang, et al. “EXTEND: Safety and efficacy of exercise training in men receiving enzalutamide (ENZ) in combination with conventional androgen deprivation therapy (ADT) for hormone naïve prostate cancer (HSPC).” In Ann Oncol, 29 Suppl 8:viii623–24, 2018. https://doi.org/10.1093/annonc/mdy300.064.Full Text Link to Item
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Zhang, Tian, SinJung Park, Daniella Runyambo, Michael J. Poellmann, Marco Reyes-Martinez, Zahra Mahbooba, Rebecca Green, et al. “Abstract 5702: Characterization of circulating tumor cells during immune checkpoint inhibition in metastatic renal cell carcinoma and malignant melanoma.” In Clinical Research (Excluding Clinical Trials). American Association for Cancer Research, 2018. https://doi.org/10.1158/1538-7445.am2018-5702.Full Text
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George, Daniel J., Elisabeth I. Heath, A Oliver Sartor, Guru Sonpavde, William R. Berry, Patrick Healy, Carolyn Winters, et al. “Abi Race: A prospective, multicenter study of black (B) and white (W) patients (pts) with metastatic castrate resistant prostate cancer (mCRPC) treated with abiraterone acetate and prednisone (AAP).” In Journal of Clinical Oncology, Vol. 36. AMER SOC CLINICAL ONCOLOGY, 2018.Link to Item
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Armstrong, Andrew J., Santosh Gupta, Patrick Healy, Gabor Kemeny, Lauren Beth Leith, Michael Zalutsky, Charles Spritzer, et al. “Genomic and phenotypic evidence for prostate cancer osteomimicry in circulating tumor cells from men with metastatic castration resistant prostate cancer (mCRPC) treated with radium-223.” In Journal of Clinical Oncology, 36:5029–5029. American Society of Clinical Oncology (ASCO), 2018. https://doi.org/10.1200/jco.2018.36.15_suppl.5029.Full Text
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Armstrong, Andrew J., Susan Halabi, Jun Luo, David M. Nanus, Paraskevi Giannakakou, Russell Zelig Szmulewitz, Daniel Costin Danila, et al. “The PROPHECY trial: Multicenter prospective trial of circulating tumor cell (CTC) AR-V7 detection in men with mCRPC receiving abiraterone (A) or enzalutamide (E).” In Journal of Clinical Oncology, 36:5004–5004. American Society of Clinical Oncology (ASCO), 2018. https://doi.org/10.1200/jco.2018.36.15_suppl.5004.Full Text
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Autio, Karen A., Emmanuel S. Antonarakis, Tina M. Mayer, Ulka N. Vaishampayan, Daniel H. Shevrin, Michael Roger Harrison, Scott T. Tagawa, et al. “Phase 2, randomized, 3-arm study of abiraterone acetate and prednisone (AAP), AAP plus degarelix (AAP+D), and degarelix (D) alone for patients (pts) with biochemically-recurrent prostate cancer (PC) following radical prostatectomy (RP).” In Journal of Clinical Oncology, 36:5016–5016. American Society of Clinical Oncology (ASCO), 2018. https://doi.org/10.1200/jco.2018.36.15_suppl.5016.Full Text
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Gupta, Santosh, Daniel H. Hovelson, Scott A. Tomlins, Gabor Kemeny, Chia-Jen Liu, Daniel J. George, Colin Rothwell, et al. “Analysis of genomic alterations in matched circulating tumor cell DNA (CTC DNA) and plasma tumor DNA (ctDNA) in men with metastatic castration resistant prostate cancer (mCRPC).” In Journal of Clinical Oncology, 36:5065–5065. American Society of Clinical Oncology (ASCO), 2018. https://doi.org/10.1200/jco.2018.36.15_suppl.5065.Full Text
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Higano, Celestia S., Andrew J. Armstrong, A Oliver Sartor, Nicholas J. Vogelzang, Philip W. Kantoff, David G. McLeod, Christopher Michael Pieczonka, et al. “Cerebrovascular event (CVE) outcome and overall survival (OS) in patients (pts) treated with sipuleucel-T (sip-T) for metastatic castration-resistant prostate cancer (mCRPC): results from the PROCEED registry.” In Journal of Clinical Oncology, 36:e17018–e17018. American Society of Clinical Oncology (ASCO), 2018. https://doi.org/10.1200/jco.2018.36.15_suppl.e17018.Full Text
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Sartor, A Oliver, Celestia S. Higano, Matthew R. Cooperberg, Nicholas J. Vogelzang, Shaker R. Dakhil, Christopher Michael Pieczonka, Jeff Vacirca, et al. “Sipuleucel-T (sip-T) overall survival (OS) and clinical outcomes by baseline (BL) prostate-specific antigen (PSA) quartiles in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC): PROCEED registry.” In Journal of Clinical Oncology, 36:5041–5041. American Society of Clinical Oncology (ASCO), 2018. https://doi.org/10.1200/jco.2018.36.15_suppl.5041.Full Text
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Shantzer, Lindsey, Michala Ritz, Bennett B. Chin, Jorge Oldan, Aseem Anand, Taofik Oyekunle, Monika Anand, Andrew J. Armstrong, Daniel J. George, and Megan Ann McNamara. “Patterns of bone scan and pain response following treatment with Ra-223 in metastatic castrate resistant prostate cancer (mCRPC).” In Journal of Clinical Oncology, 36:e17011–e17011. American Society of Clinical Oncology (ASCO), 2018. https://doi.org/10.1200/jco.2018.36.15_suppl.e17011.Full Text
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Zhang, Tian, Rebecca Garland Austin, Sally E. Park, Daniella Runyambo, Rengasamy Boominathan, Chandra Rao, Elizabeth Bronson, et al. “Expression of immune checkpoints (ICs) on circulating tumor cells (CTCs) in men with metastatic prostate cancer (mPC).” In Journal of Clinical Oncology, 36:5059–5059. American Society of Clinical Oncology (ASCO), 2018. https://doi.org/10.1200/jco.2018.36.15_suppl.5059.Full Text
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Armstrong, Andrew J., Santosh Gupta, Patrick Healy, Gabor Kemeny, Lauren Beth Leith, Michael Zalutsky, Charles Spritzer, et al. “Genomic and phenotypic evidence for prostate cancer osteomimicry in circulating tumor cells from men with metastatic castration resistant prostate cancer (mCRPC) treated with radium-223.” In Journal of Clinical Oncology, 36:160–160. American Society of Clinical Oncology (ASCO), 2018. https://doi.org/10.1200/jco.2018.36.6_suppl.160.Full Text
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Concepcion, Raoul, Andrew J. Armstrong, Lawrence Ivan Karsh, Stefan Holmstrom, Cristina Ivanescu, Curtis Dunshee, Neeraj Agarwal, et al. “Impact of enzalutamide (ENZA) vs. bicalutamide (BIC) on health-related quality of life (HRQoL) of patients (pts) with castration-resistant prostate cancer (CRPC): STRIVE study.” In Journal of Clinical Oncology, 36:234–234. American Society of Clinical Oncology (ASCO), 2018. https://doi.org/10.1200/jco.2018.36.6_suppl.234.Full Text
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Freedland, Stephen J., Jenifer Allen, Andrew J. Armstrong, Judd W. Moul, Howard M. Sandler, Dana Levin, Lauren E. Howard, and Pao-hwa Lin. “Interim analysis of a prospective randomized trial of dietary carbohydrate restriction for men with a rising PSA after failed primary treatment: Carbohydrate and Prostate Study 2 (CAPS2).” In Journal of Clinical Oncology, 36:382–382. American Society of Clinical Oncology (ASCO), 2018. https://doi.org/10.1200/jco.2018.36.6_suppl.382.Full Text
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Koontz, Bridget F., Karen E. Hoffman, Patrick Healy, Daniel J. George, Michael Roger Harrison, Tian Zhang, W Robert Lee, et al. “Phase II trial of 6 months ADT/abiraterone acetate plus prednisone (AAP) and definitive radiotherapy (AbiRT) for men with intermediate to high risk localized prostate cancer.” In Journal of Clinical Oncology, 36:11–11. American Society of Clinical Oncology (ASCO), 2018. https://doi.org/10.1200/jco.2018.36.6_suppl.11.Full Text
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McNamara, Megan Ann, Michala Ritz, Bennett Chin, Jorge Oldan, Aseem Anand, Taofik Oyekunle, Monika Anand, Andrew J. Armstrong, and Daniel J. George. “Patterns of progression in bone and soft tissue following treatment with Ra-223 in metastatic castrate resistant prostate cancer (mCRPC).” In Journal of Clinical Oncology, 36:222–222. American Society of Clinical Oncology (ASCO), 2018. https://doi.org/10.1200/jco.2018.36.6_suppl.222.Full Text
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Sumanasuriya, Semini, Aurelius Gabriel Omlin, Andrew J. Armstrong, Gerhardt Attard, Kim N. Chi, Charlotte L. Bevan, David J. Waugh, et al. “Consensus statement on circulating biomarkers for advanced prostate cancer.” In Journal of Clinical Oncology, 36:299–299. American Society of Clinical Oncology (ASCO), 2018. https://doi.org/10.1200/jco.2018.36.6_suppl.299.Full Text
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Zhang, Tian, Rebecca Garland Austin, Sally E. Park, Daniella Runyambo, Rengasamy Boominathan, Chandra Rao, Elizabeth Bronson, et al. “Expression of immune checkpoints on circulating tumor cells in men with metastatic prostate cancer (mPC).” In Journal of Clinical Oncology, 36:191–191. American Society of Clinical Oncology (ASCO), 2018. https://doi.org/10.1200/jco.2018.36.6_suppl.191.Full Text
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Zhu, Jason, Matthew D. Tucker, Patrick Healy, Michael Sandon Humeniuk, Casey Jarvis, Daniel J. George, and Andrew J. Armstrong. “Clinical utility of Foundation One tissue molecular profiling in men with metastatic prostate cancer.” In Journal of Clinical Oncology, 36:318–318. American Society of Clinical Oncology (ASCO), 2018. https://doi.org/10.1200/jco.2018.36.6_suppl.318.Full Text
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Armstrong, A. J., P. Lin, C. S. Higano, P. Iversen, C. N. Sternberg, B. Tombal, D. Phung, T. Parli, A. Krivoshik, and T. M. Beer. “Prognostic associations of prostate-specific antigen (PSA) decline with survival, radiographic response and progression in chemotherapy-naiive men with metastatic castration-resistant prostate cancer (mCRPC) treated with enzalutamide.” In Annals of Oncology, Vol. 28. OXFORD UNIV PRESS, 2017.Link to Item
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Armstrong, Andrew J., Susan Halabi, Patrick Healy, Joshi J. Alumkal, Carolyn Winters, Julie Kephart, Rhonda L. Bitting, et al. “Phase II trial of the PI3 kinase inhibitor buparlisib (BKM-120) with or without enzalutamide in men with metastatic castration resistant prostate cancer.” In Eur J Cancer, 81:228–36, 2017. https://doi.org/10.1016/j.ejca.2017.02.030.Full Text Link to Item
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Armstrong, A., C. Bui, K. Fitch, T Goss Sawhney, B. Brown, S. Flanders, M. Balk, J. Deangelis, and J. Chambers. “Docetaxel chemotherapy in metastatic castration-resistant prostate cancer: cost of care in Medicare and commercial populations.” In Curr Med Res Opin, 33:1133–39, 2017. https://doi.org/10.1080/03007995.2017.1308919.Full Text Link to Item
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Armstrong, Andrew J., Lars Edenbrandt, Eva Bondesson, Aseem Anand, Orjan Nordle, Michael Anthony Carducci, and Michael J. Morris. “Phase 3 prognostic analysis of the automated bone scan index (aBSI) in men with bone-metastatic castration-resistant prostate cancer (CRPC).” In Journal of Clinical Oncology, 35:5006–5006. American Society of Clinical Oncology (ASCO), 2017. https://doi.org/10.1200/jco.2017.35.15_suppl.5006.Full Text
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Humeniuk, Michael Sandon, Rajan T. Gupta, Megan Ann McNamara, Sundhar Ramalingam, Michael Roger Harrison, Daniel J. George, Yuan Wu, Patrick Healy, and Andrew J. Armstrong. “Association of neuroendocrine phenotype with platinum chemotherapy outcomes in men with metastatic prostate cancer.” In Journal of Clinical Oncology, 35:e16532–e16532. American Society of Clinical Oncology (ASCO), 2017. https://doi.org/10.1200/jco.2017.35.15_suppl.e16532.Full Text
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Jaganathan, Hamsa, Anne Roc, Andrew J. Armstrong, Daniel J. George, and Wendy Turell. “The impact of continuing medical education (CME) programs in metastatic castration-resistant prostate cancer (CRPC).” In Journal of Clinical Oncology, 35:e18280–e18280. American Society of Clinical Oncology (ASCO), 2017. https://doi.org/10.1200/jco.2017.35.15_suppl.e18280.Full Text
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Armstrong, Andrew J., Michael S. Humeniuk, Patrick Healy, Russell Szmulewitz, Carolyn Winters, Julie Kephart, Michael R. Harrison, et al. “Phase Ib Trial of Cabazitaxel and Tasquinimod in Men With Heavily Pretreated Metastatic Castration Resistant Prostate Cancer (mCRPC): The CATCH Trial.” In Prostate, 77:385–95, 2017. https://doi.org/10.1002/pros.23277.Full Text Link to Item
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Beer, Tomasz M., Andrew J. Armstrong, Dana Rathkopf, Yohann Loriot, Cora N. Sternberg, Celestia S. Higano, Peter Iversen, et al. “Enzalutamide in Men with Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer: Extended Analysis of the Phase 3 PREVAIL Study.” In Eur Urol, 71:151–54, 2017. https://doi.org/10.1016/j.eururo.2016.07.032.Full Text Link to Item
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Bryce, A. H., J. J. Alumkal, A. Armstrong, C. S. Higano, P. Iversen, C. N. Sternberg, D. E. Rathkopf, et al. “A post hoc analysis of radiographic progression with nonrising prostate-specific antigen in patients with metastatic castration-resistant prostate cancer (mCRPC) in the PREVAIL study.” In Annals of Oncology, 27:vi258, 2016. https://doi.org/10.1093/annonc/mdw372.44.Full Text
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Sternberg, Cora, Andrew Armstrong, Roberto Pili, Siobhan Ng, Robert Huddart, Neeraj Agarwal, Denis Khvorostenko, et al. “Randomized, Double-Blind, Placebo-Controlled Phase III Study of Tasquinimod in Men With Metastatic Castration-Resistant Prostate Cancer.” In J Clin Oncol, 34:2636–43, 2016. https://doi.org/10.1200/JCO.2016.66.9697.Full Text Link to Item
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Armstrong, Andrew J., Fred Saad, Neal D. Shore, Karim Fizazi, De Phung, Carl Dmuchowski, Mohammad Hirmand, David Forer, Howard I. Scher, and Johann S. De Bono. “Surrogacy analysis of prostate-specific antigen (PSA) decline for improved overall survival (OS) with enzalutamide (ENZ) in AFFIRM.” In Journal of Clinical Oncology, 34:5062–5062. American Society of Clinical Oncology (ASCO), 2016. https://doi.org/10.1200/jco.2016.34.15_suppl.5062.Full Text
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Vogelzang, Nicholas J., Andrew J. Armstrong, Celestia S. Higano, A Oliver Sartor, Christopher Michael Pieczonka, Raoul S. Concepcion, Ronald F. Tutrone, et al. “Treatment patterns for metastatic castration-resistant prostate cancer (mCRPC) in oncology (ONC) urology (URO) practices: Data from the PROCEED registry.” In Journal of Clinical Oncology, 34:e16503–e16503. American Society of Clinical Oncology (ASCO), 2016. https://doi.org/10.1200/jco.2016.34.15_suppl.e16503.Full Text
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Armstrong, A. J., S. Halabi, P. Healy, W. R. Lee, B. F. Koontz, J. W. Moul, K. Mundy, et al. “A phase 2 multimodality trial of docetaxel/prednisone with sunitinib followed by salvage radiation therapy in men with PSA recurrent prostate cancer after radical prostatectomy.” In Prostate Cancer Prostatic Dis, 19:100–106, 2016. https://doi.org/10.1038/pcan.2015.59.Full Text Link to Item
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Armstrong, Andrew J., Celestia S. Higano, A Oliver Sartor, Nicholas J. Vogelzang, William R. Berry, David F. Penson, Vahan Kassabian, et al. “Changing characteristics of patients treated with sipuleucel-T (sip-T) over time: Real-world experience from the PROCEED registry.” In Journal of Clinical Oncology, 34:320–320. American Society of Clinical Oncology (ASCO), 2016. https://doi.org/10.1200/jco.2016.34.2_suppl.320.Full Text
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Armstrong, Andrew J., Fred Saad, Neal D. Shore, Karim Fizazi, De Phung, Carl Frank Dmuchowski, Mohammad Hirmand, David Forer, Howard I. Scher, and Johann S. De Bono. “Surrogacy analysis of prostate-specific antigen (PSA) decline for improved overall survival (OS) with enzalutamide (ENZ) in AFFIRM.” In Journal of Clinical Oncology, 34:266–266. American Society of Clinical Oncology (ASCO), 2016. https://doi.org/10.1200/jco.2016.34.2_suppl.266.Full Text
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George, Daniel J., Susan Halabi, Patrick Healy, Sarah Gemberling, Carolyn Winters, Kelly Mundy, Michael Roger Harrison, Russell Zelig Szmulewitz, and Andrew J. Armstrong. “Phase Ib trial of docetaxel, prednisone, and pazopanib, in men with metastatic castration resistant prostate cancer (mCRPC).” In Journal of Clinical Oncology, 34:275–275. American Society of Clinical Oncology (ASCO), 2016. https://doi.org/10.1200/jco.2016.34.2_suppl.275.Full Text
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Higano, Celestia S., Andrew J. Armstrong, Matthew R. Cooperberg, Raoul S. Concepcion, Ronald F. Tutrone, Carl A. Olsson, Christopher Michael Pieczonka, et al. “Analysis of the PROCEED registry by baseline prostate-specific antigen (PSA) quartiles: Preliminary analysis of real-world sipuleucel-T (sip-T) use.” In Journal of Clinical Oncology, 34:193–193. American Society of Clinical Oncology (ASCO), 2016. https://doi.org/10.1200/jco.2016.34.2_suppl.193.Full Text
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Morris, Michael J., Tomasz M. Beer, Yohann Loriot, Celestia S. Higano, Andrew J. Armstrong, Cora N. Sternberg, Johann S. De Bono, et al. “Correlation between radiographic progression-free survival (rPFS) and overall survival (OS): Results from PREVAIL.” In Journal of Clinical Oncology, 34:182–182. American Society of Clinical Oncology (ASCO), 2016. https://doi.org/10.1200/jco.2016.34.2_suppl.182.Full Text
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Penson, David F., Andrew J. Armstrong, Raoul S. Concepcion, Kenneth Wu, Fong Wang, Andrew P. Krivoshik, De Phung, and Celestia S. Higano. “Sensitivity analyses for progression-free survival (PFS) and radiographic PFS (rPFS) from the phase II STRIVE trial comparing enzalutamide (ENZA) with bicalutamide (BIC) in men with castration-resistant prostate cancer (CRPC).” In Journal of Clinical Oncology, 34:169–169. American Society of Clinical Oncology (ASCO), 2016. https://doi.org/10.1200/jco.2016.34.2_suppl.169.Full Text
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Sartor, A Oliver, Matthew R. Cooperberg, Andrew J. Armstrong, Nicholas J. Vogelzang, Jeffrey L. Vacirca, Mark C. Scholz, Shaker R. Dakhil, et al. “Real-world experience of therapeutic sequencing and time to first anticancer intervention (ACI) following sipuleucel-T (sip-T): Initial data from the PROCEED registry.” In Journal of Clinical Oncology, 34:194–194. American Society of Clinical Oncology (ASCO), 2016. https://doi.org/10.1200/jco.2016.34.2_suppl.194.Full Text
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Sternberg, Cora N., Andrew J. Armstrong, Roberto Pili, Tore Nederman, and Michael Anthony Carducci. “A Phase 3, randomized, double-blind, placebo-controlled study of tasquinimod (TASQ) in men with metastatic castration-resistant prostate cancer (mCRPC), secondary endpoints.” In Journal of Clinical Oncology, 34:239–239. American Society of Clinical Oncology (ASCO), 2016. https://doi.org/10.1200/jco.2016.34.2_suppl.239.Full Text
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Ware, Kathryn E., Daneen Schaeffer, Tian Zhang, Mariano A. Garcia-Blanco, and Andrew J. Armstrong. “Abstract 1847: AR-V7 regulation during epithelial plasticity.” In Endocrinology. American Association for Cancer Research, 2015. https://doi.org/10.1158/1538-7445.am2015-1847.Full Text
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Armstrong, Andrew J., Samuel Broderick, Tim Eisen, Walter Michael Stadler, Robert J. Jones, Jorge A. Garcia, Ulka N. Vaishampayan, et al. “Final clinical results of a randomized phase II international trial of everolimus vs. sunitinib in patients with metastatic non-clear cell renal cell carcinoma (ASPEN).” In Journal of Clinical Oncology, Vol. 33. AMER SOC CLINICAL ONCOLOGY, 2015.Link to Item
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Higano, Celestia S., A Oliver Sartor, Nicholas J. Vogelzang, Shaker R. Dakhil, Raoul S. Concepcion, Christopher Michael Pieczonka, Jeffrey L. Vacirca, et al. “Administration of sipuleucel-T (sip-T) infusions (infs) outside of the clinical trial setting: Data from the PROCEED registry.” In Journal of Clinical Oncology, 33:e16027–e16027. American Society of Clinical Oncology (ASCO), 2015. https://doi.org/10.1200/jco.2015.33.15_suppl.e16027.Full Text
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Li, Jing, Joshua Beaver, Rhonda Lynn Bitting, Simon Gregory, and Andrew J. Armstrong. “Genomic analysis of circulating tumor cells (CTCs) from men with metastatic castration resistant prostate cancer (mCRPC) in the context of enzalutamide therapy.” In Journal of Clinical Oncology, 33:5042–5042. American Society of Clinical Oncology (ASCO), 2015. https://doi.org/10.1200/jco.2015.33.15_suppl.5042.Full Text
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Morris, Michael J., Patrick Hilden, Martin Edwin Gleave, Andrew J. Armstrong, Michael Anthony Carducci, Fred Saad, Erica Simone Dayan, et al. “Efficacy analysis of a phase III study of androgen deprivation therapy (ADT) +/- docetaxel (D) for men with biochemical relapse (BCR) after prostatectomy.” In Journal of Clinical Oncology, 33:5011–5011. American Society of Clinical Oncology (ASCO), 2015. https://doi.org/10.1200/jco.2015.33.15_suppl.5011.Full Text
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Scher, Howard I., Michael J. Morris, Walter Michael Stadler, Celestia S. Higano, Susan Halabi, Matthew Raymond Smith, Ethan M. Basch, et al. “The Prostate Cancer Working Group 3 (PCWG3) consensus for trials in castration-resistant prostate cancer (CRPC).” In Journal of Clinical Oncology, 33:5000–5000. American Society of Clinical Oncology (ASCO), 2015. https://doi.org/10.1200/jco.2015.33.15_suppl.5000.Full Text
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Zhang, Tian, Rengasamy Boominathan, Brad Foulk, Mark Carle Connelly, Chandra Rao, Gabor Kemeny, John H. Strickler, et al. “Evaluation of a novel c-MET based circulating tumor cell (CTC) biomarker in patients with gastrointestinal (GI) and genitourinary (GU) malignancies.” In Journal of Clinical Oncology, Vol. 33. AMER SOC CLINICAL ONCOLOGY, 2015.Link to Item
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Graff, Julie Nicole, Giulia Baciarello, Andrew J. Armstrong, Celestia S. Higano, Peter Iversen, David Forer, Harry H. Mansbach, et al. “Clinical outcomes and safety in men ≥ 75 and < 75 years with metastatic castration-resistant prostate cancer (mCRPC) treated with enzalutamide in the phase 3 PREVAIL trial.” In Journal of Clinical Oncology, 33:200–200. American Society of Clinical Oncology (ASCO), 2015. https://doi.org/10.1200/jco.2015.33.7_suppl.200.Full Text
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Tutrone, Ronald F., Chiledum Ahaghotu, Andrew J. Armstrong, Celestia S. Higano, Matthew R. Cooperberg, Laurence H. Belkoff, Carl A. Olsson, et al. “Characteristics of African Americans (AAs) treated with sipuleucel-T (sip-T): Comparison of clinical trial and real-world experience.” In Journal of Clinical Oncology, 33:272–272. American Society of Clinical Oncology (ASCO), 2015. https://doi.org/10.1200/jco.2015.33.7_suppl.272.Full Text
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Zhang, Tian, Rengasamy Boominathan, Brad Foulk, Mark Carle Connelly, Chandra Rao, Gabor Kemeny, Herbert Hurwitz, Mariano A. Garcia-Blanco, and Andrew J. Armstrong. “Evaluation of a novel c-MET based circulating tumor cell (CTC) biomarker in patients with gastrointestinal malignancies.” In Journal of Clinical Oncology, 33:84–84. American Society of Clinical Oncology (ASCO), 2015. https://doi.org/10.1200/jco.2015.33.3_suppl.84.Full Text
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Bhavsar, N. A., M. R. Harrison, L. J. Howie, A. J. Armstrong, K. Davis, Q. Chen, M. R. Pupa, A. Abernethy, D. J. George, and B. R. Hirsch. “1072PEXPERIENCE OF PATIENTS TREATED WITH SIPULEUCEL-T IN AN ACADEMIC SETTING.” In Ann Oncol, 25:iv369–70, 2014. https://doi.org/10.1093/annonc/mdu342.25.Full Text Link to Item
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Furay, A., L. T. Nordquist, S. R. Dakhil, N. B. Green, E. I. Heath, R. F. Tutrone, N. J. Vogelzang, et al. “Impact of Prior Radiation Treatment on Sipuleucel-T Product Parameters in PROCEED Patients.” In International Journal of Radiation Oncology*Biology*Physics, 90:S407–8. Elsevier BV, 2014. https://doi.org/10.1016/j.ijrobp.2014.05.1296.Full Text
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Armstrong, Andrew J., Bertrand Tombal, Cora N. Sternberg, Celestia S. Higano, Dana E. Rathkopf, Yohann Loriot, Fred Saad, et al. “Primary, secondary, and quality-of-life endpoint results from PREVAIL, a phase 3 study of enzalutamide in men with metastatic castration resistant prostate cancer (mCRPC).” In Journal of Clinical Oncology, 32:5007–5007. American Society of Clinical Oncology (ASCO), 2014. https://doi.org/10.1200/jco.2014.32.15_suppl.5007.Full Text
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Halabi, Susan, William Kevin Kelly, Haojin Zhou, Andrew J. Armstrong, David Quinn, Karim Fizazi, Nicole C. Solomon, et al. “The site of visceral metastases (mets) to predict overall survival (OS) in castration-resistant prostate cancer (CRPC) patients (pts): A meta-analysis of five phase III trials.” In Journal of Clinical Oncology, 32:5002–5002. American Society of Clinical Oncology (ASCO), 2014. https://doi.org/10.1200/jco.2014.32.15_suppl.5002.Full Text
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Li, Jing, Joshua Beaver, Rhonda Lynn Bitting, Simon Gregory, and Andrew J. Armstrong. “Genomic analysis of circulating tumor cells (CTCs) from men with metastatic castration resistant prostate cancer (mCRPC) in the context of enzalutamide therapy.” In Journal of Clinical Oncology, 32:e16059–e16059. American Society of Clinical Oncology (ASCO), 2014. https://doi.org/10.1200/jco.2014.32.15_suppl.e16059.Full Text
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Morris, Michael J., Martin Edwin Gleave, Andrew J. Armstrong, Michael Anthony Carducci, Fred Saad, Kristine Peregrino Lacuna, and Howard I. Scher. “A randomized, open label, multicenter, phase 3, 2-arm study of androgen deprivation with leuprolide (L), ± docetaxel (D) for clinically asymptomatic prostate cancer (PC) subjects with a rising PSA following definitive local therapy: Safety results.” In Journal of Clinical Oncology, 32:5022–5022. American Society of Clinical Oncology (ASCO), 2014. https://doi.org/10.1200/jco.2014.32.15_suppl.5022.Full Text
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Morris, Michael J., Yohann Loriot, Tomasz M. Beer, Celestia S. Higano, Andrew J. Armstrong, Cora N. Sternberg, Johann Sebastian De Bono, et al. “Sensitivity analyses for radiographic progression-free survival (rPFS): Results from the phase 3 PREVAIL trial comparing enzalutamide to placebo.” In Journal of Clinical Oncology, 32:5054–5054. American Society of Clinical Oncology (ASCO), 2014. https://doi.org/10.1200/jco.2014.32.15_suppl.5054.Full Text
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Zhang, Tian, Mallika S. Dhawan, Patrick Healy, Daniel J. George, Jorge Oldan, Bennett Chin, and Andrew J. Armstrong. “Clinical benefit of docetaxel or enzalutamide after progression on first-line abiraterone acetate and prednisone in men with metastatic castration resistant prostate cancer (mCRPC).” In Journal of Clinical Oncology, 32:e16031–e16031. American Society of Clinical Oncology (ASCO), 2014. https://doi.org/10.1200/jco.2014.32.15_suppl.e16031.Full Text
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Armstrong, Andrew J., Jing Li, Joshua Beaver, Rhonda Lynn Bitting, and Simon Gregory. “Genomic analysis of circulating tumor cells (CTCs) from men with metastatic castration resistant prostate cancer (mCRPC) in the context of enzalutamide therapy.” In Journal of Clinical Oncology, 32:65–65. American Society of Clinical Oncology (ASCO), 2014. https://doi.org/10.1200/jco.2014.32.4_suppl.65.Full Text
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Armstrong, Andrew J., Rhonda Lynn Bitting, Gabor Kemeny, and Daniel J. George. “Evidence for circulating tumor cell (CTC) alkaline phosphatase (AP) expression in men with bone-metastatic castration-resistant prostate cancer (CRPC) during abiraterone acetate treatment.” In Journal of Clinical Oncology, 32:178–178. American Society of Clinical Oncology (ASCO), 2014. https://doi.org/10.1200/jco.2014.32.4_suppl.178.Full Text
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Beer, Tomasz M., Andrew J. Armstrong, Cora N. Sternberg, Celestia S. Higano, Peter Iversen, Yohann Loriot, Dana E. Rathkopf, et al. “Enzalutamide in men with chemotherapy-naive metastatic prostate cancer (mCRPC): Results of phase III PREVAIL study.” In Journal of Clinical Oncology, 32:LBA1–LBA1. American Society of Clinical Oncology (ASCO), 2014. https://doi.org/10.1200/jco.2014.32.4_suppl.lba1.Full Text
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Finkelstein, Steven E., Luke T. Nordquist, Shaker R. Dakhil, Nathan B. Green, Elisabeth I. Heath, Ronald Tutrone, Nicholas J. Vogelzang, et al. “Impact of prior radiation treatment (tx) on sipuleucel-T (sip-T) product parameters in PROCEED patients (pts).” In Journal of Clinical Oncology, 32:183–183. American Society of Clinical Oncology (ASCO), 2014. https://doi.org/10.1200/jco.2014.32.4_suppl.183.Full Text
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Nabhan, Chadi, A Oliver Sartor, Matthew R. Cooperberg, Andrew J. Armstrong, Jeffrey L. Vacirca, Raoul S. Concepcion, William R. Berry, et al. “Sipuleucel-T in metastatic castration-resistant prostate cancer (mCRPC) patients ≥80 years-old: Data from PROCEED.” In Journal of Clinical Oncology, 32:64–64. American Society of Clinical Oncology (ASCO), 2014. https://doi.org/10.1200/jco.2014.32.4_suppl.64.Full Text
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Vogelzang, Nicholas J., Jeffrey L. Vacirca, Philip W. Kantoff, Mark C. Scholz, Shaker R. Dakhil, Luke T. Nordquist, Celestia S. Higano, et al. “Effect of prior abiraterone (ABI) or enzalutamide (ENZ) on sipuleucel-T (sip-T) manufacture in PROCEED patients (pts).” In Journal of Clinical Oncology, 32:185–185. American Society of Clinical Oncology (ASCO), 2014. https://doi.org/10.1200/jco.2014.32.4_suppl.185.Full Text
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Armstrong, Andrew J., Reza Kaboteh, Michael Anthony Carducci, Jan-Erik Damber, Walter Michael Stadler, Hansen Mats, Lars Edenbrandt, et al. “Association of bone scan index (BSI) with prognostic biomarkers and survival in men with metastatic castration-resistant prostate cancer (mCRPC) enrolled in a prospective randomized controlled trial of tasquinimod.” In Journal of Clinical Oncology, Vol. 31. AMER SOC CLINICAL ONCOLOGY, 2013.Link to Item
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Armstrong, Andrew J., Susan Halabi, Tim Eisen, Walter Michael Stadler, Robert R. Jones, Ultra N. Vaishampayan, Jorge A. Garcia, et al. “ASPEN: A randomized phase II trial of everolimus versus sunitinib in patients with metastatic non-clear cell renal cell carcinoma.” In Journal of Clinical Oncology, Vol. 31. AMER SOC CLINICAL ONCOLOGY, 2013.Link to Item
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Bitting, Rhonda Lynn, Patrick Healy, Susan Halabi, Daniel J. George, Jung Hyun Ko, and Andrew J. Armstrong. “Evaluation of clinical phenotype, survival, and circulating tumor cell (CTC) enumeration in men with metastatic castration-resistant prostate cancer (mCRPC).” In Journal of Clinical Oncology, Vol. 31. AMER SOC CLINICAL ONCOLOGY, 2013.Link to Item
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Halabi, Susan, Chen-Yen Lin, Eric Jay Small, Andrew J. Armstrong, Ellen B. Kaplan, Daniel Peter Petrylak, Cora N. Sternberg, et al. “A prognostic model for predicting overall survival in metastatic castrate-resistant prostate cancer (mCRPC) men treated with second-line chemotherapy.” In Journal of Clinical Oncology, Vol. 31. AMER SOC CLINICAL ONCOLOGY, 2013.Link to Item
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Higano, Celestia S., Andrew J. Armstrong, Matthew R. Cooperberg, Philip W. Kantoff, James Bailen, Raoul S. Concepcion, Vahan Kassabian, et al. “Impact of prior docetaxel (D) on sipuleucel-T (sip-T) product parameters in PROCEED patients (pts).” In Journal of Clinical Oncology, Vol. 31. AMER SOC CLINICAL ONCOLOGY, 2013.Link to Item
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Armstrong, Andrew J., Tong Shen, Susan Halabi, Gabor Kemeny, Rhonda Lynn Bitting, Patricia Kartcheske, Elizabeth Embree, et al. “A phase II trial of temsirolimus in men with castration-resistant metastatic prostate cancer.” In Journal of Clinical Oncology, 31:105–105. American Society of Clinical Oncology (ASCO), 2013. https://doi.org/10.1200/jco.2013.31.6_suppl.105.Full Text
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Halabi, Susan, Chen-Yen Lin, Eric Jay Small, Andrew J. Armstrong, Ellen B. Kaplan, Daniel Peter Petrylak, Cora N. Sternberg, et al. “A model for predicting overall survival in men with metastatic castrate-resistant prostate cancer (CRPC) for whom first-line chemotherapy failed.” In Journal of Clinical Oncology, Vol. 31. AMER SOC CLINICAL ONCOLOGY, 2013. https://doi.org/10.1200/jco.2013.31.6_suppl.24.Full Text Link to Item
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Scher, Howard I., Karim Fizazi, Fred Saad, Kim N. Chi, Mary-Ellen Taplin, Cora N. Sternberg, Andrew J. Armstrong, Mohammad Hirmand, David Forer, and Johann Sebastian De Bono. “Impact of on-study corticosteroid use on efficacy and safety in the phase III AFFIRM study of enzalutamide (ENZA), an androgen receptor inhibitor.” In Journal of Clinical Oncology, Vol. 31. AMER SOC CLINICAL ONCOLOGY, 2013. https://doi.org/10.1200/jco.2013.31.6_suppl.6.Full Text Link to Item
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Schweizer, Michael Thomas, Aditya Bardia, Amanda L. Blackford, Jianqing Lin, Andrew J. Armstrong, Serina King, Michelle A. Rudek, Srinivasan Thomas Yegnasubramanian, and Michael Anthony Carducci. “A prostate cancer clinical trials consortium trial of disulfiram (D) in men with nonmetastatic recurrent prostate cancer (PCa).” In Journal of Clinical Oncology, Vol. 31. AMER SOC CLINICAL ONCOLOGY, 2013. https://doi.org/10.1200/jco.2013.31.6_suppl.219.Full Text Link to Item
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Corman, J., N. Dawson, S. Hall, C. Nabhan, A. Ferrari, A. J. Armstrong, M. I. Murdock, F. Stewart, N. Sheikh, and D. P. Petrylak. “OPENACT: PHASE 2, OPEN-LABEL STUDY OF SIPULEUCEL-T IN METASTATIC CASTRATE-RESISTANT PROSTATE CANCER (MCRPC).” In Annals of Oncology, 23:311–311. OXFORD UNIV PRESS, 2012.Link to Item
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Scher, H. I., K. Fizazi, F. Saad, K. Chi, M. Taplin, C. N. Sternberg, A. J. Armstrong, M. Hirmand, B. Selby, and J. S. de Bono. “ASSOCIATION OF BASELINE CORTICOSTEROID WITH OUTCOMES IN A MULTIVARIATE ANALYSIS OF THE PHASE 3 AFFIRM STUDY OF ENZALUTAMIDE (ENZA), AN ANDROGEN RECEPTOR SIGNALING INHIBITOR (ARSI).” In Annals of Oncology, 23:297–297. OXFORD UNIV PRESS, 2012.Link to Item
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Sonpavde, G., G. R. Pond, A. J. Armstrong, M. D. Galsky, B. A. Wood, S. Wang, J. Paolini, M. Lechuga, M. R. Smith, and M. D. Michaelson. “ASSOCIATION OF PROGRESSION BY PROSTATE CANCER WORKING GROUP (PCWG)-2 CRITERIA AND SURVIVAL IN METASTATIC CASTRATION RESISTANT PROSTATE CANCER.” In Annals of Oncology, 23:297–98. OXFORD UNIV PRESS, 2012.Link to Item
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Armstrong, Andrew J., Michael Haggman, Walter Michael Stadler, Jeffrey R. Gingrich, Vasily J. Assikis, Jonathan Polikoff, Samuel R. Denmeade, et al. “Tasquinimod and survival in men with metastatic castration-resistant prostate cancer: Results of long-term follow-up of a randomized phase II placebo-controlled trial.” In Journal of Clinical Oncology, Vol. 30. AMER SOC CLINICAL ONCOLOGY, 2012.Link to Item
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Bitting, Rhonda Lynn, Rengasamy Boominathan, Chandra Rao, Elizabeth Embree, Daniel J. George, Mark C. Connelly, Gabor Kemeny, Mariano Garcia-Blanco, and Andrew J. Armstrong. “Isolation of circulating tumor cells using a novel EMT-based capture method.” In Journal of Clinical Oncology, Vol. 30. AMER SOC CLINICAL ONCOLOGY, 2012.Link to Item
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De Bono, Johann Sebastian, Karim Fizazi, Fred Saad, Mary-Ellen Taplin, Cora N. Sternberg, Kurt Miller, Peter Mulders, et al. “Primary, secondary, and quality-of-life endpoint results from the phase III AFFIRM study of MDV3100, an androgen receptor signaling inhibitor.” In Journal of Clinical Oncology, Vol. 30. AMER SOC CLINICAL ONCOLOGY, 2012.Link to Item
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Halabi, Susan, Andrew J. Armstrong, A Oliver Sartor, Johann Sebastian De Bono, Ellen B. Kaplan, and Eric Jay Small. “Prostate-specific antigen decline (PSA) as a surrogate for overall survival (OS) in patients (pts) with metastatic castrate-resistant prostate cancer (mCRPC) who failed first-line chemotherapy.” In Journal of Clinical Oncology, Vol. 30. AMER SOC CLINICAL ONCOLOGY, 2012.Link to Item
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George, D. J., S. Halabi, A. J. Zurita, P. Creel, K. Mundy, J. D. Turnbull, S. E. Yenser Wood, et al. “Investigator-initiated pilot study of sunitinib malate in patients with newly diagnosed prostate cancer prior to prostatectomy: A trial of the DoD/PCF Prostate Cancer Clinical Trials Consortium.” In Journal of Clinical Oncology, 29:4664–4664. American Society of Clinical Oncology (ASCO), 2011. https://doi.org/10.1200/jco.2011.29.15_suppl.4664.Full Text
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Araujo, J., P. Mathew, A. J. Armstrong, E. L. Braud, E. Posadas, M. Lonberg, G. Gallick, G. C. Trudel, P. Paliwal, and C. J. Logothetis. “7028 Dasatinib and docetaxel combination treatment for patients with metastatic castration-resistant prostate cancer (CRPC): analysis of Study CA180–086.” In European Journal of Cancer Supplements, 7:415–415. Elsevier BV, 2009. https://doi.org/10.1016/s1359-6349(09)71406-5.Full Text
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Araujo, J., A. J. Armstrong, E. L. Braud, E. Posadas, M. Lonberg, G. E. Gallick, G. C. Trudel, P. Paliwal, S. Agrawal, and C. J. Logothetis. “Dasatinib and docetaxel combination treatment for patients with castration-resistant progressive prostate cancer: A phase I/II study (CA180086).” In Journal of Clinical Oncology, Vol. 27. AMER SOC CLINICAL ONCOLOGY, 2009.Link to Item
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Armstrong, A. J., S. Halabi, I. F. Tannock, D. J. George, R. Dewit, and M. Eisenberger. “Development of risk groups in metastatic castration-resistant prostate cancer (mCRPC) to facilitate the identification of active chemotherapy regimens.” In Journal of Clinical Oncology, Vol. 27. AMER SOC CLINICAL ONCOLOGY, 2009.Link to Item
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Armstrong, A. J. “Commentary.” In Oncology Report, 2008.
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Armstrong, A. J., M. A. Eisenberger, E. S. Garrett-Mayer, Y Ou Yang, M. A. Carducci, R. de Wit, and I. Tannock. “Analysis of prostate-specific antigen decline as a surrogate for overall survival in metastatic hormone-refractory prostate cancer (HRPC).” In Journal of Clinical Oncology, Vol. 25. AMER SOC CLINICAL ONCOLOGY, 2007.Link to Item
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Eisenberger, M., E. S. Garrett-Mayer, Y Ou Yang, R. de Wit, I. Tannock, and A. J. Armstrong. “A multivariate prognostic nomogram incorporating PSA kinetics in hormone-refractory metastatic prostate cancer (HRPC).” In Journal of Clinical Oncology, Vol. 25. AMER SOC CLINICAL ONCOLOGY, 2007.Link to Item
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Speca, J. C., A. L. Mears, P. A. Creel, S. E. Yenser, J. C. Bendell, M. A. Morse, H. I. Hurwitz, A. J. Armstrong, and D. J. George. “Phase I study of PTK787/ZK222584 (PTK/ZK) and RAD001 for patients with advanced solid tumors and dose expansion in renal cell carcinoma patients.” In Journal of Clinical Oncology, Vol. 25. AMER SOC CLINICAL ONCOLOGY, 2007.Link to Item
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