Scholars@Duke
Anita Shlesinger

Selected Publications

A 'rich-get-richer' mechanism drives patchy dynamics and resistance evolution in antibiotic-treated bacteria.

Journal Article Molecular systems biology · August 2024 Bacteria in nature often form surface-attached communities that initially comprise distinct subpopulations, or patches. For pathogens, these patches can form at infection sites, persist during antibiotic treatment, and develop into mature biofilms. Evidenc ... Full text Cite

The collapse of cooperation during range expansion of Pseudomonas aeruginosa.

Journal Article Nature microbiology · May 2024 Cooperation is commonly believed to be favourable in spatially structured environments, as these systems promote genetic relatedness that reduces the likelihood of exploitation by cheaters. Here we show that a Pseudomonas aeruginosa population that exhibit ... Full text Cite

A change of phase.

Journal Article Nature chemical biology · April 2023 Full text Cite

Advances and challenges in programming pattern formation using living cells.

Journal Article Current opinion in chemical biology · June 2022 Spatial patterning of cell populations is a ubiquitous phenomenon in nature. Patterns occur at various length and time scales and exhibit immense diversity. In addition to offering a deeper understanding of the emergence of patterns in nature, the ability ... Full text Cite

Substrate Utilization and Competitive Interactions Among Soil Bacteria Vary With Life-History Strategies.

Journal Article Frontiers in microbiology · January 2022 Microorganisms have evolved various life-history strategies to survive fluctuating resource conditions in soils. However, it remains elusive how the life-history strategies of microorganisms influence their processing of organic carbon, which may affect mi ... Full text Cite

Persistence of the ground beetle (Coleoptera: Carabidae) microbiome to diet manipulation.

Journal Article PloS one · January 2021 Host-associated microbiomes can play important roles in the ecology and evolution of their insect hosts, but bacterial diversity in many insect groups remains poorly understood. Here we examine the relationship between host environment, host traits, and mi ... Full text Cite

Abstract 6293: Novel approach for automated sequential immunoassay for quantitation and characterization of PI3K-Akt pathway proteins

Journal Article Cancer Research · August 15, 2020 AbstractThe PI3K-Akt signaling pathway modulates cell growth, survival and apoptosis, and this pathway is frequently altered in human cancers, contributing resistance to radiation and chemotherapy treatment. ... Full text Cite