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Anne Frances Buckley

Associate Professor of Pathology
Pathology
Dept of Pathology, BOX_3712, Durham, NC 27710

Overview


My basic research focus is on neurogenic stem cells and their involvement in brain development and brain tumors. I work in mouse models using inducible in vivo genetic systems, live imaging, and tissue culture, in addition to histological and biochemical methods.
My clinical research interests include neuromuscular diseases. I collaborate with colleagues at Duke on basic and translational research in this area.

Current Appointments & Affiliations


Associate Professor of Pathology · 2023 - Present Pathology, Clinical Science Departments
Affiliate of the Duke Regeneration Center · 2021 - Present Duke Regeneration Center, Basic Science Departments

Recent Publications


Cytostatic hypothermia and its impact on glioblastoma and survival.

Journal Article Sci Adv · November 25, 2022 Patients with glioblastoma (GBM) have limited options and require novel approaches to treatment. Here, we studied and deployed nonfreezing "cytostatic" hypothermia to stunt GBM growth. This growth-halting method contrasts with ablative, cryogenic hypotherm ... Full text Link to item Cite
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Recent Grants


Promoting Podocyte Protective Natriuretic Peptide Signaling in Proteinuric Kidney Diseases

ResearchCo-Principal Investigator · Awarded by Department of Defense · 2019 - 2022

Targeting TRPC6 to treat focal segmental glomerulosclerosis (FSGS)

ResearchPathologist · Awarded by Amgen, Inc. · 2016 - 2019

Supplemental Funding for Phase 1/2 study of Clenbuterol for the Treatment of Pompe Disease

Clinical TrialCo Investigator · Awarded by Roivant Sciences, Inc. · 2015 - 2016

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Education, Training & Certifications


The University of Chicago · 2003 M.D.
The University of Chicago · 2001 Ph.D.