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Annick Desjardins

Professor of Neurosurgery
Neurosurgery, Neuro-Oncology
Duke Box 3624, Durham, NC 27710
the Preston Robert Tisch Brain, Rm. 047 Baker House, DUMC 3624, Durham, NC 27710

Current Appointments & Affiliations


Professor of Neurosurgery · 2021 - Present Neurosurgery, Neuro-Oncology, Neurosurgery
Professor in Neurology · 2021 - Present Neurology, General & Community Neurology, Neurology
Member of the Duke Cancer Institute · 2003 - Present Duke Cancer Institute, Institutes and Centers

In the News


Published June 6, 2016
Duke’s Poliovirus Therapy Shows Survival Benefit in Early Patients
Published May 16, 2016
Poliovirus Therapy Wins 'Breakthrough' Status
Published June 1, 2015
Poliovirus Study Finds That Less Is More in Brain Tumor Treatment

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Recent Publications


Clinical trial of feasibility for mindfulness intervention for patients with newly diagnosed high grade glioma.

Journal Article J Neurooncol · November 5, 2025 PURPOSE: With a bleak prognosis for malignant glioma, maintaining quality of life (QoL) and decreasing distress are essential in patient clinical care. Mindfulness meditation is a mind-body therapy that is being investigated as a non-pharmacological strate ... Full text Link to item Cite

A surgical window of opportunity trial evaluating the effect of the PCSK9 inhibitor evolocumab on tumoral MHC-I expression and CD8+ infiltration in glioma.

Journal Article Sci Rep · October 23, 2025 Many cancers evade immunosurveillance by downregulating surface major histocompatibility class (MHC)-I. Proprotein convertase subtilisin/kexin type 9 (PCSK9) promotes MHC-I degradation and is elevated in glioma. Evolocumab is a clinically approved PCSK9 in ... Full text Link to item Cite

Response Assessment in Neuro-Oncology (RANO) 2009-2025: Broad scope and implementation-A progress report.

Journal Article Neuro Oncol · October 14, 2025 Since its first activities in 2008 and 2009, the Response Assessment in NeuroOncology (RANO) group has given guidance on response assessment, trial design, and trial procedures to improve and standardize the way clinical trials in neurooncological studies ... Full text Link to item Cite
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Recent Grants


McCain/Bayh Glioblastoma Consortium

Clinical TrialCo Investigator · Awarded by Department of Defense · 2025 - 2029

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Education, Training & Certifications


University of Sherbrooke (Canada) · 1998 M.D.