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Anusha Gopalakrishnan

Research Associate, Senior
Molecular Genetics and Microbiology
4200 MSRB III, Box 3580, Durham, NC 27710
4200 MSRB III Box 3580, 3 Genome Court, Durham, NC 27710

Research Interests


With a professional degree in Microbiology from Pune, the cultural capital of India, I stepped into the United States in 2005, to realize my passion for infectious disease. For my doctoral and my previous post-doctoral work, as a “Molecular parasitologist”, I aimed at developing an experimental challenge for vaccine development towards malaria. With my experience in gene expression, DNA recombination, replication, damage and repairs I came to Duke to continue my research on infectious diseases by looking at various aspects at a molecular, biochemical and immunological level. Lack of convenient genetic tools has hampered the identification of Chlamydia virulence molecules. My present study in the Valdivia lab involves developing and optimizing genetic tools in Chlamydia to investigate how these virulence molecules are regulated to cause pathology.

Selected Grants


Functional characterization of early Chlamydia effectors

ResearchSenior Research Associate · Awarded by National Institutes of Health · 2018 - 2023

The impact of genetic diversity among Akkermansia strains on the effectivenes of immune checkpoint inhibitors in cancer immunotherapies

ResearchSenior Research Associate · Awarded by National Institutes of Health · 2020 - 2022

Structure-Function Analysis of Chlamydia Secretion Chaperones

ResearchSenior Research Associate · Awarded by National Institutes of Health · 2016 - 2022

Genetic Analysis in an intractable gut microbe

ResearchScholar · Awarded by National Institutes of Health · 2016 - 2018

Forward and Reverse Genetics in Chlamydia

ResearchPostdoctoral Associate · Awarded by National Institutes of Health · 2012 - 2017

The role of cyclic-di-AMP in the regulation of Chlamydia cellular functions

ResearchPostdoctoral Associate · Awarded by National Institutes of Health · 2013 - 2016