Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Pulmonary and Critical Care Fellowship, Medicine, Duke University 2017 - 2019
  • Chief Residency, Internal Medicine, Duke University 2016 - 2017
  • Pulmonary and Critical Care Fellowship, Medicine, Duke University 2015 - 2016
  • Pulmonary and Critical Care Fellowship, Medicine, Duke University School of Medicine 2015 - 2016
  • Residency, Internal Medicine, Duke University 2012 - 2015
  • Internal Medicine Residency, Medicine, Duke University School of Medicine 2012 - 2015
  • M.D., Case Western Reserve University, School of Medicine 2012
• 

  Previous Appointments & Affiliations

  • Assistant Professor of Medicine, Medicine, Pulmonary, Allergy, and Critical Care Medicine, Medicine 2020
  • Medical Instructor in the Department of Medicine, Medicine, Pulmonary, Allergy, and Critical Care Medicine, Medicine 2019 - 2020
  • Medical Instructor in the Department of Medicine, Medicine, General Internal Medicine, Medicine 2016 - 2017
• Research
• 

  Selected Grants

  • Complement Pathway Activation in Idiopathic Pulmonary Fibrosis and other Progressive Fibrosing Interstitial Lung Diseases (K23) awarded by National Institutes of Health 2023 - 2028
  • CHARACTERIZING THE ILD CARE CONTINUUM USING REAL-WORLD EVIDENCE awarded by Genentech, Inc. 2021 - 2022
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Swaminathan, Aparna C., Alec McConnell, Sarah Peskoe, Mustafa R. Bashir, Erika Bush Buckley, Courtney Frankel, Daniel Turner, et al. “Evaluation of Frailty Measures and Short-Term Outcomes after Lung Transplantation.” Chest, January 2023, S0012-3692(23)00121-6. https://doi.org/10.1016/j.chest.2023.01.017.
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    • Wang, Ziyi, Leith Rankine, Elianna A. Bier, David Mummy, Junlan Lu, Alex Church, Robert M. Tighe, et al. “Using hyperpolarized 129Xe gas-exchange MRI to model the regional airspace, membrane, and capillary contributions to diffusing capacity.” J Appl Physiol (1985) 130, no. 5 (May 1, 2021): 1398–1409. https://doi.org/10.1152/japplphysiol.00702.2020.
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    • Swaminathan, Aparna C., Jamie L. Todd, and Scott M. Palmer. “Advances in Human Lung Transplantation.” Annual Review of Medicine 72 (January 2021): 135–49. https://doi.org/10.1146/annurev-med-080119-103200.
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    • Swaminathan, Aparna C., Hongmei Zhu, Victor Tapson, Yuliya Lokhnygina, Abby Poms, Zach Kelleher, Elijah Gaspard, et al. “Treatment-related biomarkers in pulmonary hypertension patients on oral therapies.” Respir Res 21, no. 1 (November 19, 2020): 304. https://doi.org/10.1186/s12931-020-01566-y.
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    • Swaminathan, Aparna C., Hongmei Zhu, Victor Tapson, Yuliya Lokhnygina, Abby Poms, Zachary Kelleher, Elijah Gaspard, et al. “Treatment-related biomarkers in pulmonary hypertension patients on oral therapies,” November 6, 2020. https://doi.org/10.21203/rs.3.rs-63089/v2.
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    • Swaminathan, Aparna C., and Jamie L. Todd. “That Was Then, This Is Now: A Fresh Look at Idiopathic Pulmonary Fibrosis Biomarkers in the Antifibrotic Era.” Chest 158, no. 4 (October 2020): 1321–22. https://doi.org/10.1016/j.chest.2020.05.564.
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    • Swaminathan, Aparna C., Hongmei Zhu, Victor Tapson, Yuliya Lokhnygina, Abby Poms, Zachary Kelleher, Elijah Gaspard, et al. “Treatment-related Biomarkers in Pulmonary Hypertension Patients on Oral Therapies,” August 24, 2020. https://doi.org/10.21203/rs.3.rs-63089/v1.
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    • O’Brien, Emily C., Anne S. Hellkamp, Megan L. Neely, Aparna Swaminathan, Shaun Bender, Laurie D. Snyder, Daniel A. Culver, et al. “Disease Severity and Quality of Life in Patients With Idiopathic Pulmonary Fibrosis: A Cross-Sectional Analysis of the IPF-PRO Registry.” Chest 157, no. 5 (May 2020): 1188–98. https://doi.org/10.1016/j.chest.2019.11.042.
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    • Swaminathan, Aparna C., John M. Carney, Tina D. Tailor, and Scott M. Palmer. “Overview and Challenges of Bronchiolar Disorders.” Ann Am Thorac Soc 17, no. 3 (March 2020): 253–63. https://doi.org/10.1513/AnnalsATS.201907-569CME.
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    • Wang, Ziyi, Elianna A. Bier, Aparna Swaminathan, Kishan Parikh, John Nouls, Mu He, Joseph G. Mammarappallil, Sheng Luo, Bastiaan Driehuys, and Sudarshan Rajagopal. “Diverse cardiopulmonary diseases are associated with distinct xenon magnetic resonance imaging signatures.” Eur Respir J 54, no. 6 (December 2019). https://doi.org/10.1183/13993003.00831-2019.
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    • Swaminathan, Aparna C., Megan L. Neely, Courtney W. Frankel, Fran L. Kelly, Slavé Petrovski, Michael T. Durheim, Erika Bush, et al. “Lung Transplant Outcomes in Patients With Pulmonary Fibrosis With Telomere-Related Gene Variants.” Chest 156, no. 3 (September 2019): 477–85. https://doi.org/10.1016/j.chest.2019.03.030.
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    • Boggan, Joel C., Aparna Swaminathan, Samantha Thomas, David L. Simel, Aimee K. Zaas, and Jonathan G. Bae. “Improving Timely Resident Follow-Up and Communication of Results in Ambulatory Clinics Utilizing a Web-Based Audit and Feedback Module.” J Grad Med Educ 9, no. 2 (April 2017): 195–200. https://doi.org/10.4300/JGME-D-16-00460.1.
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    • Abril, Maria K., Adam S. Barnett, Kara Wegermann, Eric Fountain, Andrew Strand, Benjamin M. Heyman, Britton A. Blough, et al. “Diagnosis of Capnocytophaga canimorsus Sepsis by Whole-Genome Next-Generation Sequencing.” Open Forum Infect Dis 3, no. 3 (September 2016): ofw144. https://doi.org/10.1093/ofid/ofw144.
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    • Swaminathan, Aparna C., Alex C. Dusek, and Tim J. McMahon. “Treatment-related biomarkers in pulmonary hypertension.” Am J Respir Cell Mol Biol 52, no. 6 (June 2015): 663–73. https://doi.org/10.1165/rcmb.2014-0438TR.
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    • Menachem, Jonathan N., Aparna C. Swaminathan, Thomas M. Bashore, Cary C. Ward, Joseph G. Rogers, Carmelo A. Milano, and Chetan B. Patel. “Initial Experience of Left Ventricular Assist Device Support for Adult Patients with Transposition of the Great Vessels.” Congenit Heart Dis 10, no. 5 (2015): 382–86. https://doi.org/10.1111/chd.12264.
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    • Navar-Boggan, Ann Marie, Alexander Fanaroff, Aparna Swaminathan, Adrienne Belasco, Judith Stafford, Bimal Shah, and Eric D. Peterson. “The impact of a measurement and feedback intervention on blood pressure control in ambulatory cardiology practice.” Am Heart J 167, no. 4 (April 2014): 466–71. https://doi.org/10.1016/j.ahj.2013.12.015.
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    • Swaminathan, Aparna, Sreekanth Vemulapalli, Manesh R. Patel, and W Schuyler Jones. “Lower extremity amputation in peripheral artery disease: improving patient outcomes.” Vasc Health Risk Manag 10 (2014): 417–24. https://doi.org/10.2147/VHRM.S50588.
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    • Sipahi, Ilke, Aparna Swaminathan, Viswanath Natesan, Sara M. Debanne, Daniel I. Simon, and James C. Fang. “Effect of antihypertensive therapy on incident stroke in cohorts with prehypertensive blood pressure levels: a meta-analysis of randomized controlled trials.” Stroke 43, no. 2 (February 2012): 432–40. https://doi.org/10.1161/STROKEAHA.111.636829.
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  • Conference Papers

    • Mummy, D., A. Swaminathan, K. Yarnall, E. Bier, J. Lu, S. Leewiwatwong, J. Korzekwinski, and B. Driehuys. “Hyperpolarized 129Xe MRI in Healthy Control Subjects Reveals Age-Related Changes in Measurements of Ventilation and Red Blood Cell Transfer but Not Interstitial Tissue Barrier.” In American Journal of Respiratory and Critical Care Medicine, Vol. 205, 2022.
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    • Povysil, G., J. L. Todd, A. S. Allen, D. F. Dilling, H. J. Kim, M. L. Neely, I. Noth, et al. “Gene-Based Collapsing Genetic Analyses to Identify Rare Protein-Coding Variants Associated with Susceptibility to Idiopathic Pulmonary Fibrosis (IPF): Data from the IPF-PRO Registry.” In American Journal of Respiratory and Critical Care Medicine, Vol. 205, 2022.
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    • Todd, J. L., G. Povysil, A. S. Allen, D. F. Dilling, H. J. Kim, M. L. Neely, I. Noth, et al. “Association of Genetic Variants with Disease Progression in Patients with Idiopathic Pulmonary Fibrosis (IPF): Data from the IPF-PRO Registry.” In American Journal of Respiratory and Critical Care Medicine, Vol. 205, 2022.
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    • Clowse, Megan E. B., Aardra Rajendran, Amanda Eudy, Stephanie Giattino, Aparna Swaminathan, and Andra H. James. “Pregnancy Outcomes in Patients with Interstitial Lung Disease.” In Arthritis Care Res (Hoboken), 2021. https://doi.org/10.1002/acr.24814.
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    • O’Brien, Emily, Anne Hellkamp, Megan Neely, Aparna Swaminathan, Shaun Bender, Laurie Snyder, Daniel Culver, et al. “DISEASE SEVERITY AND QUALITY OF LIFE IN PATIENTS WITH IDIOPATHIC PULMONARY FIBROSIS (IPF): AN ANALYSIS OF THE IPF-PRO REGISTRY.” In Chest, 156:A1579–80. Elsevier BV, 2019. https://doi.org/10.1016/j.chest.2019.08.1392.
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    • Swaminathan, Aparna, Emily O’Brien, Anne Hellkamp, Megan Neely, Shaun Bender, Laurie Snyder, Daniel Culver, et al. “HEALTH-RELATED QUALITY OF LIFE MEASURES IN IDIOPATHIC PULMONARY FIBROSIS: DATA FROM THE IPF-PRO REGISTRY.” In Chest, 156:A180–81. Elsevier BV, 2019. https://doi.org/10.1016/j.chest.2019.08.248.
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    • Bier, E., Z. Wang, A. Swaminathan, J. Nouls, M. He, J. Mammarappallil, S. Luo, B. Driehuys, and S. Rajagopal. “129Xenon MR Imaging and Spectroscopic Signatures to Differentiate Pulmonary Arterial Hypertension from Other Heart and Lung Disease.” In American Journal of Respiratory and Critical Care Medicine, Vol. 199. AMER THORACIC SOC, 2019.
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    • Swaminathan, A., Y. Lokhnygina, H. Zhu, K. Kennedy, S. N. Mason, Z. Kelleher, B. Fee, A. Poms, V. F. Tapson, and T. J. McMahon. “Asymmetric Dimethylarginine and Symmetric Dimethylarginine as Novel Biomarkers in Patients with Pulmonary (Arterial) Hypertension.” In American Journal of Respiratory and Critical Care Medicine, Vol. 197. AMER THORACIC SOC, 2018.
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    • Swaminathan, Aparna, Elianna Bier, John Nouls, Karla Kennedy, Samantha Womack, Susana Almeida-Peters, Bastiaan Driehuys, and Sudarshan Rajagopal. “Non-Invasive Diagnosis of Pulmonary Vascular Disease Using Inhaled 129-XenonMRI.” In Circulation, Vol. 138, 2018.
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    • Swaminathan, A. C., A. Poms, K. Kennedy, H. Zhu, E. Gaspard, T. A. Fortin, J. Senick, et al. “Toward Theranostic Biomarkers In Pulmonary Hypertension.” In American Journal of Respiratory and Critical Care Medicine, Vol. 193. AMER THORACIC SOC, 2016.
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    • Kamath, A. S., April Cooper, MIchael Willis, Sarah Hale, Jon Lovins, Aparna Swaminathan, and Adam Wachter. “INTER-PROFESSIONAL QUALITY IMPROVEMENT PROJECT TO IMPROVE THE SAFETY OF DISCHARGE MEDICATION RECONCILIATION PROCESS FOR HOSPITALIZED PATIENTS.” In Journal of Hospital Medicine, Vol. 4(Suppl). Wiley, n.d.
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