Skip to main content

Andrew Scott Allen

Professor of Biostatistics & Bioinformatics
Biostatistics & Bioinformatics, Division of Integrative Genomics
Duke Box 103854, Durham, NC 27710
3 Genome Ct, 1245 MSRB III, Durham, NC 27705

Overview


My research focuses on developing new statistical methods for identifying susceptibility loci involved in complex human disease.  It involves a mix of genetics, statistics, and computer science and is motivated by the complexities of real data encountered in collaborative disease-gene mapping projects.

Current Appointments & Affiliations


Professor of Biostatistics & Bioinformatics · 2019 - Present Biostatistics & Bioinformatics, Division of Integrative Genomics, Biostatistics & Bioinformatics
Director, Center for Statistical Genetics and Genomics · 2015 - Present Biostatistics & Bioinformatics, Division of Biostatistics, Biostatistics & Bioinformatics
Chief, Division of Integrative Genomics · 2018 - Present Biostatistics & Bioinformatics, Division of Biostatistics, Biostatistics & Bioinformatics

In the News


Published September 3, 2015
School of Medicine announces new Center for Statistical Genetics and Genomics

View All News

Recent Publications


Characterization and bioinformatic filtering of ambient gRNAs in single-cell CRISPR screens using CLEANSER.

Journal Article Cell Genom · February 12, 2025 Single-cell RNA sequencing CRISPR (perturb-seq) screens enable high-throughput investigation of the genome, allowing for characterization of thousands of genomic perturbations on gene expression. Ambient gRNAs, which are contaminating gRNAs, are a major so ... Full text Link to item Cite

Promoter Deletion Leading to Allele Specific Expression in a Genetically Unsolved Case of Primary Ciliary Dyskinesia.

Journal Article Am J Med Genet A · February 2025 Variation in the non-coding genome represents an understudied mechanism of disease and it remains challenging to predict if single nucleotide variants, small insertions and deletions, or structural variants in non-coding genomic regions will be detrimental ... Full text Link to item Cite
View All Publications

Recent Grants


Determining the genetic and social determinants of heart failure and mortality in patients with congenital heart disease

ResearchCo Investigator · Awarded by National Institutes of Health · 2023 - 2028

Complement Pathway Activation in Idiopathic Pulmonary Fibrosis and other Progressive Fibrosing Interstitial Lung Diseases (K23)

ResearchAdvisor · Awarded by National Heart, Lung, and Blood Institute · 2023 - 2028

Integrated Biostatistical Training for CVD Research

Inst. Training Prgm or CMEMentor · Awarded by North Carolina State University · 2022 - 2027

View All Grants

Education, Training & Certifications


Emory University · 2001 Ph.D.

External Links


Lab page