Austin Maduka

Journal Article Mol Cell Proteomics · March 2025 Under stress conditions, cells reprogram their molecular machineries to mitigate damage and promote survival. Ubiquitin signaling is globally increased during oxidative stress, controlling protein fate and supporting stress defenses at several subcellular ... Full text Link to item Cite

Localized K63 ubiquitin signaling is regulated by VCP/p97 during oxidative stress.

Journal Article bioRxiv · June 21, 2024 Under stress conditions, cells reprogram their molecular machineries to mitigate damage and promote survival. Ubiquitin signaling is globally increased during oxidative stress, controlling protein fate and supporting stress defenses at several subcellular ... Full text Link to item Cite

Expanding Role of Ubiquitin in Translational Control.

Journal Article International journal of molecular sciences · February 2020 The eukaryotic proteome has to be precisely regulated at multiple levels of gene expression, from transcription, translation, and degradation of RNA and protein to adjust to several cellular conditions. Particularly at the translational level, regulation i ... Full text Cite

Fatty acid synthase inhibits the O-GlcNAcase during oxidative stress.

Journal Article The Journal of biological chemistry · April 2017 The dynamic post-translational modification O-linked β-N-acetylglucosamine (O-GlcNAc) regulates thousands of nuclear, cytoplasmic, and mitochondrial proteins. Cellular stress, including oxidative stress, results in increased O-G ... Full text Cite