Scholars@Duke
Aysenil Belger

Aysenil Belger

Adjunct Assistant Professor in Radiology
Radiology
abelger@med.unc.edu
Brain Imaging and Analysis Ctr, Box 3918, Durham, NC 27710
40 Duke Medicine Circle, Davison 414, Box 3918, Durham, NC 27710

Selected Publications

Reliability of mismatch negativity event-related potentials in a multisite, traveling subjects study.

Journal Article Clin Neurophysiol · December 2020 OBJECTIVE: To determine the optimal methods for measuring mismatch negativity (MMN), an auditory event-related potential (ERP), and quantify sources of MMN variance in a multisite setting. METHODS: Reliability of frequency, duration, and double (frequency  ... Full text Link to item Cite

Deficits in auditory predictive coding in individuals with the psychosis risk syndrome: Prediction of conversion to psychosis.

Journal Article J Abnorm Psychol · August 2020 The mismatch negativity (MMN) event-related potential (ERP) component is increasingly viewed as a prediction error signal elicited when a deviant sound violates the prediction that a frequent "standard" sound will repeat. Support for this predictive coding ... Full text Link to item Cite

Covarying structural alterations in laterality of the temporal lobe in schizophrenia: A case for source-based laterality.

Journal Article NMR Biomed · June 2020 The human brain is asymmetrically lateralized for certain functions (such as language processing) to regions in one hemisphere relative to the other. Asymmetries are measured with a laterality index (LI). However, traditional LI measures are limited by a l ... Full text Link to item Cite

Stability of mismatch negativity event-related potentials in a multisite study.

Journal Article Int J Methods Psychiatr Res · June 2020 OBJECTIVES: Mismatch negativity (MMN), an auditory event-related potential sensitive to deviance detection, is smaller in schizophrenia and psychosis risk. In a multisite study, a regression approach to account for effects of site and age (12-35 years) was ... Full text Link to item Cite

The genetic architecture of the human cerebral cortex.

Journal Article Science · March 20, 2020 The cerebral cortex underlies our complex cognitive capabilities, yet little is known about the specific genetic loci that influence human cortical structure. To identify genetic variants that affect cortical structure, we conducted a genome-wide associati ... Full text Open Access Link to item Cite

Weighted average of shared trajectory: A new estimator for dynamic functional connectivity efficiently estimates both rapid and slow changes over time.

Journal Article J Neurosci Methods · January 21, 2020 BACKGROUND: Dynamic functional network connectivity (dFNC) of the brain has attracted considerable attention recently. Many approaches have been suggested to study dFNC with sliding window Pearson correlation (SWPC) being the most well-known. SWPC needs a ... Full text Link to item Cite

Evidence of Slow Neural Processing, Developmental Differences and Sensitivity to Cannabis Effects in a Sample at Clinical High Risk for Psychosis From the NAPLS Consortium Assessed With the Human Startle Paradigm.

Journal Article Front Psychiatry · 2020 ABSTRACT: Biomarkers are important in the study of the prodromal period of psychosis because they can help to identify individuals at greatest risk for future psychotic illness and provide insights into disease mechanism underlying neurodevelopmental abnor ... Full text Link to item Cite

Association Between P300 Responses to Auditory Oddball Stimuli and Clinical Outcomes in the Psychosis Risk Syndrome.

Journal Article JAMA Psychiatry · November 1, 2019 IMPORTANCE: In most patients, a prodromal period precedes the onset of schizophrenia. Although clinical criteria for identifying the psychosis risk syndrome (PRS) show promising predictive validity, assessment of neurophysiologic abnormalities in at-risk i ... Full text Link to item Cite

Characterizing Whole Brain Temporal Variation of Functional Connectivity via Zero and First Order Derivatives of Sliding Window Correlations.

Journal Article Front Neurosci · 2019 Brain functional connectivity has been shown to change over time during resting state fMRI experiments. Close examination of temporal changes have revealed a small set of whole-brain connectivity patterns called dynamic states. Dynamic functional network c ... Full text Link to item Cite

Altered Domain Functional Network Connectivity Strength and Randomness in Schizophrenia.

Journal Article Front Psychiatry · 2019 Functional connectivity is one of the most widely used tools for investigating brain changes due to schizophrenia. Previous studies have identified abnormal functional connectivity in schizophrenia patients at the resting state brain network level. This st ... Full text Link to item Cite

Disrupted network cross talk, hippocampal dysfunction and hallucinations in schizophrenia.

Conference Schizophr Res · September 2018 Hallucinations characterize schizophrenia, with approximately 59% of patients reporting auditory hallucinations and 27% reporting visual hallucinations. Prior neuroimaging studies suggest that hallucinations are linked to disrupted communication across dis ... Full text Link to item Cite

Multimodal Fusion With Reference: Searching for Joint Neuromarkers of Working Memory Deficits in Schizophrenia.

Journal Article IEEE Trans Med Imaging · January 2018 By exploiting cross-information among multiple imaging data, multimodal fusion has often been used to better understand brain diseases. However, most current fusion approaches are blind, without adopting any prior information. There is increasing interest ... Full text Link to item Cite

The neural circuitry of autism.

Journal Article Neurotox Res · October 2011 Autism is a complex neurodevelopmental disorder, characterized by deficits in social emotional, and language domains, as well as repetitive restrictive behaviors. The vast heterogeneity of the clinical and behavioral symptoms has made it rather difficult t ... Full text Link to item Cite