Scholars@Duke
Richard Stanley Bedlack

Richard Stanley Bedlack

Stewart, Hughes and Wendt Distinguished Professor
Neurology, Neuromuscular Disease
bedla001@mc.duke.edu
Duke Box 3333, Durham, NC 27710
932 Morreene Rd ROOM234, Durham, NC

Overview

1. Investigator-initiated and multi-center clinical trials testing new treatments for amyotrophic lateral sclerosis and diabetic neuropathy.

2. Epidemiologic studies to better understand the causes and variability in prognosis of amyotrophic lateral sclerosis and diabetic neuropathy.

3. Basic science studies to develop novel biomarkers for amyotrophic lateral sclerosis.

Current Appointments & Affiliations

Stewart, Hughes and Wendt Distinguished Professor · 2023 - Present Neurology, Neuromuscular Disease, Neurology
Professor of Neurology · 2018 - Present Neurology, Neuromuscular Disease, Neurology
Faculty Network Member of the Duke Institute for Brain Sciences · 2011 - Present Duke Institute for Brain Sciences, University Institutes and Centers
Associate of the Duke Initiative for Science & Society · 2017 - Present Duke Science & Society, University Initiatives & Academic Support Units

In the News

Published July 31, 2024
Study Finds Genetic Variant Among People Who Experience a Rare Recovery from ALS
Published May 4, 2023
Duke Awards 44 Distinguished Professorships
Published July 11, 2022
Watch Duke Doctors Race Cars to Raise Money for ALS

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Recent Publications

ALSUntangled #79: alpha-lipoic acid.

Journal Article Amyotroph Lateral Scler Frontotemporal Degener · May 24, 2025 Alpha-lipoic acid (ALA) is a naturally occurring fatty acid. It serves as an essential cofactor for enzymatic reactions in mitochondrial energy production, is a potent antioxidant and has anti-inflammatory effects, which are plausible mechanisms in slowing ... Full text Link to item Cite

ALSUntangled #77: Psilocybin.

Journal Article Amyotroph Lateral Scler Frontotemporal Degener · May 2025 ALSUntangled reviews alternate and off-label treatments prompted by patient interest. Here, we review psilocybin, a chemical derived from mushrooms and belonging in the category of drugs known as psychedelics. Psilocybin has plausible mechanisms for slowin ... Full text Link to item Cite
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Recent Grants

Pridopine EAP 2 (Clinical Site Agreement)

ResearchPrincipal Investigator · Awarded by Massachusetts General Hospital · 2024 - 2027

An Intermediate Expanded Access Protocol (EAP) with CNM-Au8 for Amyotrophic Lateral Sclerosis

ResearchPrincipal Investigator · Awarded by Clene Nanomedicine Inc. · 2024 - 2026

Pilot Trial to Investigate The Safety, Tolerability and Preliminary Efficacy of BL-001 Probiotic in People with ALS

Clinical TrialPrincipal Investigator · Awarded by Hop On A Cure · 2024 - 2026

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Education, Training & Certifications

University of Connecticut · 1995 M.D.
University of Connecticut · 1995 Ph.D.