Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • EMG Fellow, Medicine, Duke University 1999 - 2000
  • Neurology Resident, Medicine, Duke University 1996 - 1999
  • Medical Intern, Medicine, Duke University 1995 - 1996
  • M.D., University of Connecticut 1995
  • Ph.D., University of Connecticut 1995
• 

  Duke Appointment History

  • Associate Professor of Neurology, Neurology, Neuromuscular Disease, Neurology 2011 - 2017
  • Associate Professor of Medicine, Neurology, Clinical Science Departments 2006 - 2010
  • Assistant Professor of Medicine, Neurology, Clinical Science Departments 2002 - 2006
  • Associate in the Department of Medicine, Neurology, Clinical Science Departments 2000 - 2002
  • Instructor, Temporary in the Department of Medicine, Neurology, Clinical Science Departments 2000
• Recognition
• 

  In the News

  • NOV 17, 2017

    Duke Magazine

    Optimism and Sartorial Style in a Quest to Cure ALS Patients

  • MAY 23, 2017

    Clinical Practice Today

    ALS Trials Redesigned With Patient-Centric Approach

  • MAR 8, 2017

    Duke Health News

    A Symbol of Hope: How a Duke Doctor Inspired a Fashion Designer to Fight ALS

  • OCT 24, 2016

    NPRs All Things Considered

    Simplified study aims to quickly test a long-shot ALS treatment

  • JUN 15, 2016

    The Wall Street Journal

    Dr. Richard Bedlack probes the mystery of ALS patients who see improvement

  • NOV 16, 2015

    The News & Observer

    Tar Heel of the Week: Duke doctor collecting new ideas to fight ALS

  • AUG 13, 2015

    Duke ALS Clinic Ice Bucket Challenge 2015

  • AUG 13, 2015

    ABC 11

    Ice Bucket Challenge begins at Duke ALS Clinic and the race for a cure is on

  • AUG 13, 2015

    Durham Herald-Sun

    ‘ALS is a tough disease’

  • FEB 20, 2015

    WTVD

    New discovery made about ALS could lead to a cure

  • NOV 18, 2014

    Bedlack named to new national consortium to advance the treatment of Lou Gehrig’s disease

  • AUG 29, 2014

    It Can Get Better

  • APR 23, 2014

    Ivanhoe Broadcast News

    Giving Jan a voice: Thinking cap for ALS

  • MAR 10, 2014

    The News & Observer

    Dr. Rick Bedlack on the challenges of treating veterans with ALS
• Research
• 

  Selected Grants

  • EFFECTS OF ORAL LEVOSIMENDAN (ODM-109) ON RESPIRATORY FUNCTION IN PATIENTS WITH ALS awarded by Orion Corporation 2018 - 2020
  • A Pilot Trial of Triheptanoin for People with Amyotrophic Lateral Sclerosis (PALS) awarded by Ultragenyx Pharmaceutical 2018 - 2020
  • CYTO-5022 awarded by Cytokinetics, Inc. 2017 - 2019
  • ALS Telemedicine awarded by Amyotrophic Lateral Sclerosis Association 2018 - 2019
  • The Duke ALS Association Certified Center awarded by Amyotrophic Lateral Sclerosis Association 2018 - 2019
  • Retigabine and or Ezogabine in ALS awarded by GlaxoSmithKline 2015 - 2018
  • Neuraltus NP001 awarded by Neuraltus Pharmaceuticals, Inc 2016 - 2018
  • Integrated Genomics in Clinical ALS (GTAC) awarded by Columbia University 2016 - 2018
  • Clinical Research in ALS & Related Disorders for Therapeutic Development (CREATE) awarded by University of Miami 2014 - 2018
  • Open Label Cytokinetics (CY4031) awarded by Cytokinetics, Inc. 2016 - 2018
  • Tirasemtiv in ALS awarded by Cytokinetics, Inc. 2015 - 2018
  • ALS Telemedicine awarded by Amyotrophic Lateral Sclerosis Association 2016 - 2018
  • Diaphragm Pacer Study awarded by Synapse Biomedical, Inc 2013 - 2018
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Bedlack, R. "ALSUntangled 44: curcumin." Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 19, no. 7-8 (October 2, 2018): 623-629.  Full Text
    • van Es, MA, Stommel, E, Drory, VE, Nefussy, B, van den Berg, LH, Crayle, J, and Bedlack, R. "“ALS reversals”: demographics, disease characteristics, treatments, and co-morbidities." Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 19, no. 7-8 (October 2, 2018): 495-499.  Full Text
    • "ALSUntangled 43: copper." Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 19, no. 5-6 (July 3, 2018): 472-476.  Full Text
    • Bedlack, R, and ALSUntangled Group, . "ALSUntangled 42: Elysium health's "basis"." Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration 19, no. 3-4 (May 2018): 317-319.  Full Text
    • Earl, DE, Loochtan, AI, and Bedlack, RS. "Refractory myasthenia gravis exacerbation triggered By pembrolizumab." Muscle & Nerve 57, no. 4 (April 2018): E120-E121.  Full Text
    • Nicolas, A, Kenna, KP, Renton, AE, Ticozzi, N, Faghri, F, Chia, R, Dominov, JA, Kenna, BJ, Nalls, MA, Keagle, P, Rivera, AM, van Rheenen, W, Murphy, NA, van Vugt, JJFA, Geiger, JT, Van der Spek, RA, Pliner, HA, Shankaracharya, , Smith, BN, Marangi, G, Topp, SD, Abramzon, Y, Gkazi, AS, Eicher, JD, Kenna, A, ITALSGEN Consortium, , Mora, G, Calvo, A, Mazzini, L, Riva, N, Mandrioli, J, Caponnetto, C, Battistini, S, Volanti, P, La Bella, V, Conforti, FL, Borghero, G, Messina, S, Simone, IL, Trojsi, F, Salvi, F, Logullo, FO, D'Alfonso, S, Corrado, L, Capasso, M, Ferrucci, L, Genomic Translation for ALS Care (GTAC) Consortium, , Moreno, CDAM, Kamalakaran, S, Goldstein, DB, ALS Sequencing Consortium, , Gitler, AD, Harris, T, Myers, RM, NYGC ALS Consortium, , Phatnani, H, Musunuri, RL, Evani, US, Abhyankar, A, Zody, MC, Answer ALS Foundation, , Kaye, J, Finkbeiner, S, Wyman, SK, LeNail, A, Lima, L, Fraenkel, E, Svendsen, CN, Thompson, LM, Van Eyk, JE, Berry, JD, Miller, TM, Kolb, SJ, Cudkowicz, M, Baxi, E, Clinical Research in ALS and Related Disorders for Therapeutic Development (CReATe) Consortium, , Benatar, M, Taylor, JP, Rampersaud, E, Wu, G, Wuu, J, SLAGEN Consortium, , Lauria, G, Verde, F, Fogh, I, Tiloca, C, Comi, GP, Sorarù, G, Cereda, C, French ALS Consortium, , Corcia, P, Laaksovirta, H, Myllykangas, L, Jansson, L, Valori, M, Ealing, J, Hamdalla, H, Rollinson, S, Pickering-Brown, S, Orrell, RW, Sidle, KC, Malaspina, A, Hardy, J, Singleton, AB, Johnson, JO, Arepalli, S, Sapp, PC, McKenna-Yasek, D, Polak, M, Asress, S, Al-Sarraj, S, King, A, Troakes, C, Vance, C, de Belleroche, J, Baas, F, Ten Asbroek, ALMA, Muñoz-Blanco, JL, Hernandez, DG, Ding, J, Gibbs, JR, Scholz, SW, Floeter, MK, Campbell, RH, Landi, F, Bowser, R, Pulst, SM, Ravits, JM, MacGowan, DJL, Kirby, J, Pioro, EP, Pamphlett, R, Broach, J, Gerhard, G, Dunckley, TL, Brady, CB, Kowall, NW, Troncoso, JC, Le Ber, I, Mouzat, K, Lumbroso, S, Heiman-Patterson, TD, Kamel, F, Van Den Bosch, L, Baloh, RH, Strom, TM, Meitinger, T, Shatunov, A, Van Eijk, KR, de Carvalho, M, Kooyman, M, Middelkoop, B, Moisse, M, McLaughlin, RL, Van Es, MA, Weber, M, Boylan, KB, Van Blitterswijk, M, Rademakers, R, Morrison, KE, Basak, AN, Mora, JS, Drory, VE, Shaw, PJ, Turner, MR, Talbot, K, Hardiman, O, Williams, KL, Fifita, JA, Nicholson, GA, Blair, IP, Rouleau, GA, Esteban-Pérez, J, García-Redondo, A, Al-Chalabi, A, Project MinE ALS Sequencing Consortium, , Rogaeva, E, Zinman, L, Ostrow, LW, Maragakis, NJ, Rothstein, JD, Simmons, Z, Cooper-Knock, J, Brice, A, Goutman, SA, Feldman, EL, Gibson, SB, Taroni, F, Ratti, A, Gellera, C, Van Damme, P, Robberecht, W, Fratta, P, Sabatelli, M, Lunetta, C, Ludolph, AC, Andersen, PM, Weishaupt, JH, Camu, W, Trojanowski, JQ, Van Deerlin, VM, Brown, RH, van den Berg, LH, Veldink, JH, Harms, MB, Glass, JD, Stone, DJ, Tienari, P, Silani, V, Chiò, A, Shaw, CE, Traynor, BJ, and Landers, JE. "Genome-wide Analyses Identify KIF5A as a Novel ALS Gene." Neuron 97, no. 6 (March 2018): 1268-1283.e6.  Full Text
    • ALSUntangled Group, . "ALSUntangled 41: "Eric Is Winning"." Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration 19, no. 1-2 (February 2018): 157-160.  Full Text
    • Horton, DK, Graham, S, Punjani, R, Wilt, G, Kaye, W, Maginnis, K, Webb, L, Richman, J, Bedlack, R, Tessaro, E, and Mehta, P. "A spatial analysis of amyotrophic lateral sclerosis (ALS) cases in the United States and their proximity to multidisciplinary ALS clinics, 2013." Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration 19, no. 1-2 (February 2018): 126-133.  Full Text
    • Bedlack, R. "Perspective: Untangling the ALS X-Files." Nature 550, no. 7676 (October 2017): S122-.  Full Text
    • ALSUntangled Group, . "ALSUntangled No. 37: Inosine." Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration 18, no. 3-4 (May 2017): 309-312. (Review)  Full Text
    • ALSUNTANGLED GROUP, . "ALSUntangled No. 36: Accilion." Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration 18, no. 1-2 (February 2017): 142-147. (Review)  Full Text
    • ALSUntangled Group, . "ALSUntangled 38: L-serine." Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration 18, no. 1-2 (February 2017): 148-151.  Full Text
    • Mukherjee, N, McBurney-Lin, S, Kuo, A, Bedlack, R, and Tseng, H. "Retinal thinning in amyotrophic lateral sclerosis patients without ophthalmic disease." Plos One 12, no. 9 (January 2017): e0185242-null.  Full Text
    • Nieves, JW, Gennings, C, Factor-Litvak, P, Hupf, J, Singleton, J, Sharf, V, Oskarsson, B, Fernandes Filho, JAM, Sorenson, EJ, D'Amico, E, Goetz, R, Mitsumoto, H, and Amyotrophic Lateral Sclerosis Multicenter Cohort Study of Oxidative Stress (ALS COSMOS) Study Group, . "Association Between Dietary Intake and Function in Amyotrophic Lateral Sclerosis." Jama Neurology 73, no. 12 (December 2016): 1425-1432.  Full Text
    • "ALSUntangled No. 34: GM604." Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration 17, no. 7-8 (October 2016): 617-621.  Full Text
    • ALSUntangled Group, . "ALSUntangled No. 35: Hyperbaric Oxygen Therapy." Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration 17, no. 7-8 (October 2016): 622-624.  Full Text
    • Lee, CM, Lee, JD, Hobson-Webb, LD, Bedlack, RS, and Salama, JK. "Treatment of Thymoma-Associated Myasthenia Gravis With Stereotactic Body Radiotherapy: A Case Report." Annals of internal medicine 165, no. 4 (August 2016): 300-301. (Letter)  Full Text
    • Bedlack, RS, Vaughan, T, Wicks, P, Heywood, J, Sinani, E, Selsov, R, Macklin, EA, Schoenfeld, D, Cudkowicz, M, and Sherman, A. "How common are ALS plateaus and reversals?." Neurology 86, no. 9 (March 2016): 808-812.  Full Text
    • Murphy, J, Factor-Litvak, P, Goetz, R, Lomen-Hoerth, C, Nagy, PL, Hupf, J, Singleton, J, Woolley, S, Andrews, H, Heitzman, D, Bedlack, RS, Katz, JS, Barohn, RJ, Sorenson, EJ, Oskarsson, B, Fernandes Filho, JAM, Kasarskis, EJ, Mozaffar, T, Rollins, YD, Nations, SP, Swenson, AJ, Koczon-Jaremko, BA, Mitsumoto, H, and ALS COSMOS, . "Cognitive-behavioral screening reveals prevalent impairment in a large multicenter ALS cohort." Neurology 86, no. 9 (March 2016): 813-820.  Full Text
    • Karam, CY, Paganoni, S, Joyce, N, Carter, GT, and Bedlack, R. "Palliative Care Issues in Amyotrophic Lateral Sclerosis: An Evidenced-Based Review." The American journal of hospice & palliative care 33, no. 1 (February 2016): 84-92. (Review)  Full Text
    • Bedlack, RS, Joyce, N, Carter, GT, Paganoni, S, and Karam, C. "Complementary and Alternative Therapies in Amyotrophic Lateral Sclerosis." Neurologic Clinics 33, no. 4 (November 2015): 909-936. (Review)  Full Text
    • Miller, RG, Block, G, Katz, JS, Barohn, RJ, Gopalakrishnan, V, Cudkowicz, M, Zhang, JR, McGrath, MS, Ludington, E, Appel, SH, Azhir, A, and Phase 2 Trial NP001 Investigators, . "Randomized phase 2 trial of NP001-a novel immune regulator: Safety and early efficacy in ALS." Neurology(R) neuroimmunology & neuroinflammation 2, no. 3 (June 2015): e100-.  Full Text
    • ALSUntangled Group, . "ALSUntangled: introducing The Table of Evidence." Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration 16, no. 1-2 (March 2015): 142-145. (Review)  Full Text
    • Cirulli, ET, Lasseigne, BN, Petrovski, S, Sapp, PC, Dion, PA, Leblond, CS, Couthouis, J, Lu, Y-F, Wang, Q, Krueger, BJ, Ren, Z, Keebler, J, Han, Y, Levy, SE, Boone, BE, Wimbish, JR, Waite, LL, Jones, AL, Carulli, JP, Day-Williams, AG, Staropoli, JF, Xin, WW, Chesi, A, Raphael, AR, McKenna-Yasek, D, Cady, J, Vianney de Jong, JMB, Kenna, KP, Smith, BN, Topp, S, Miller, J, Gkazi, A, FALS Sequencing Consortium, , Al-Chalabi, A, van den Berg, LH, Veldink, J, Silani, V, Ticozzi, N, Shaw, CE, Baloh, RH, Appel, S, Simpson, E, Lagier-Tourenne, C, Pulst, SM, Gibson, S, Trojanowski, JQ, Elman, L, McCluskey, L, Grossman, M, Shneider, NA, Chung, WK, Ravits, JM, Glass, JD, Sims, KB, Van Deerlin, VM, Maniatis, T, Hayes, SD, Ordureau, A, Swarup, S, Landers, J, Baas, F, Allen, AS, Bedlack, RS, Harper, JW, Gitler, AD, Rouleau, GA, Brown, R, Harms, MB, Cooper, GM, Harris, T, Myers, RM, and Goldstein, DB. "Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways." Science (New York, N.Y.) 347, no. 6229 (March 2015): 1436-1441.  Full Text
    • ALSUntangled Group, . "ALSUntangled No. 29: MitoQ." Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration 16, no. 5-6 (January 2015): 427-429.  Full Text
    • Paganoni, S, Karam, C, Joyce, N, Bedlack, R, and Carter, GT. "Comprehensive rehabilitative care across the spectrum of amyotrophic lateral sclerosis." Neurorehabilitation 37, no. 1 (January 2015): 53-68. (Review)  Full Text
    • ALSUntangled Group, . "ALSUntangled No. 26: lunasin." Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration 15, no. 7-8 (December 2014): 622-626.  Full Text
    • Mitsumoto, H, Factor-Litvak, P, Andrews, H, Goetz, RR, Andrews, L, Rabkin, JG, McElhiney, M, Nieves, J, Santella, RM, Murphy, J, Hupf, J, Singleton, J, Merle, D, Kilty, M, Heitzman, D, Bedlack, RS, Miller, RG, Katz, JS, Forshew, D, Barohn, RJ, Sorenson, EJ, Oskarsson, B, Fernandes Filho, JAM, Kasarskis, EJ, Lomen-Hoerth, C, Mozaffar, T, Rollins, YD, Nations, SP, Swenson, AJ, Shefner, JM, Andrews, JA, Koczon-Jaremko, BA, and ALS COSMOS Study Group, . "ALS Multicenter Cohort Study of Oxidative Stress (ALS COSMOS): study methodology, recruitment, and baseline demographic and disease characteristics." Amyotrophic lateral sclerosis & frontotemporal degeneration 15, no. 3-4 (June 2014): 192-203.  Full Text
    • Rabourn, J, and Bedlack, RS. "SAPs: a different perspective." The American journal of bioethics : AJOB 14, no. 11 (January 2014): 19-20.  Full Text
    • ALSUntangled Group, , Fournier, C, Bedlack, B, Hardiman, O, Heiman-Patterson, T, Gutmann, L, Bromberg, M, Ostrow, L, Carter, G, Kabashi, E, Bertorini, T, Mozaffar, T, Andersen, P, Dietz, J, Gamez, J, Dimachkie, M, Wang, Y, Wicks, P, Heywood, J, Novella, S, Rowland, LP, Pioro, E, Kinsley, L, Mitchell, K, Glass, J, Sathornsumetee, S, Kwiecinski, H, Baker, J, Atassi, N, Forshew, D, Ravits, J, Conwit, R, Jackson, C, Sherman, A, Dalton, K, Tindall, K, Gonzalez, G, Robertson, J, Phillips, L, Benatar, M, Sorenson, E, Shoesmith, C, Nash, S, Maragakis, N, Moore, D, Caress, J, Boylan, K, Armon, C, Grosso, M, Gerecke, B, Wymer, J, Oskarsson, B, Bowser, R, Drory, V, Shefner, J, Lechtzin, N, Leitner, M, Miller, R, Mitsumoto, H, Levine, T, Russell, J, Sharma, K, Saperstein, D, McClusky, L, MacGowan, D, Licht, J, Verma, A, Strong, M, Lomen-Hoerth, C, Tandan, R, Rivner, M, Kolb, S, Polak, M, Rudnicki, S, Kittrell, P, Quereshi, M, Sachs, G, Pattee, G, Weiss, M, Kissel, J, Goldstein, J, Rothstein, J, Pastula, D, Gleb, L, Ogino, M, Rosenfeld, J, Carmi, E, Oster, C, Barkhaus, P, and Valor, E. "ALS Untangled No. 20: the Deanna protocol." Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration 14, no. 4 (May 2, 2013): 319-323. (Review)  Full Text
    • Chad, DA, Rowland, LP, Armon, C, Bedlack, R, Durham, H, Factor-Litvak, P, Heiman-Patterson, T, Heitzman, D, Lacomis, D, Ludolph, A, Maragakis, N, Miller, R, Pattee, G, Shoesmith, C, Sorenson, E, and Turner, MR. "Peer recommendations on how to improve clinical research, and Conference wrap-up." Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 14, no. SUPPL1 (2013): 67-73.  Full Text
    • Sherman, AV, Gubitz, AK, Al-Chalabi, A, Bedlack, R, Berry, J, Conwit, R, Harris, BT, Horton, DK, Kaufmann, P, Leitner, ML, Miller, R, Shefner, J, Vonsattel, JP, and Mitsumoto, H. "Infrastructure resources for clinical research in amyotrophic lateral sclerosis." Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 14, no. SUPPL1 (2013): 53-61.  Full Text
    • ALSUntangled Group, . "ALS untangled No. 17: "when ALS is lyme"." Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 13, no. 5 (September 2012): 487-491. (Review)  Full Text
    • Scherer, K, and Bedlack, RS. "Diaphragm pacing in amyotrophic lateral sclerosis: a literature review." Muscle Nerve 46, no. 1 (July 2012): 1-8. (Review)  Full Text  Link to Item
    • ALSUntangled Group, . "ALSUntangled No. 16: cannabis." Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 13, no. 4 (June 2012): 400-404. (Review)  Full Text
    • Kamel, F, Umbach, DM, Bedlack, RS, Richards, M, Watson, M, Alavanja, MCR, Blair, A, Hoppin, JA, Schmidt, S, and Sandler, DP. "Pesticide exposure and amyotrophic lateral sclerosis." Neurotoxicology 33, no. 3 (June 2012): 457-462. (Review)  Full Text
    • Bedlack, R, Hardiman, O, Bertorini, T, Mozaffar, T, Andersen, P, Dietz, J, Gamez, J, Dimachkie, M, Wang, Y, Wicks, P, Heywood, J, Novella, S, Rowland, LP, Pioro, E, Kinsley, L, Mitchell, K, Glass, J, Sathornsumetee, S, Kwiecinski, H, Baker, J, Atassi, N, Forshew, D, Ravits, J, Conwit, R, Jackson, C, Sherman, A, Dalton, K, Tindall, K, Gonzalez, G, Robertson, J, Phillips, L, Benatar, M, Sorenson, E, Shoesmith, C, Nash, S, Marigakis, N, Moore, D, Caress, J, Boylan, K, Armon, C, and Grosso, M et al. "ALS untangled 15: Coconut oil." Amyotrophic Lateral Sclerosis 13, no. 3 (2012): 328-330.  Full Text
    • Caulfield, T, Zarzeczny, A, Bedlack, R, Claudio, JO, Foti, A, Ganz, P, Herrmann, I, Hyun, I, Karbani, T, Lyall, D, Rooke, H, Sipp, D, Staz, M, Sullivan, WF, Willemse, L, and Wonders, C. "Stem cell tourism and Canadian family physicians." Canadian Family Physician 58, no. 4 (2012): 365-368+e182-185-.
    • Pastula, DM, Moore, DH, and Bedlack, RS. "Creatine for amyotrophic lateral sclerosis/motor neuron disease." The Cochrane Database of Systematic Reviews 12 (January 2012): CD005225-null. (Review)  Full Text
    • Pastula, DM, Moore, DH, and Bedlack, RS. "Creatine for amyotrophic lateral sclerosis/motor neuron disease." COCHRANE DATABASE OF SYSTEMATIC REVIEWS , no. 12 (2012).  Full Text  Link to Item
    • Bedlack, RS. "Compassionate use of stem cells for ALS: popovers and hot air." Amyotroph Lateral Scler 12, no. 5 (September 2011): 313-314. (Letter)  Full Text  Link to Item
    • Bedlack, RS, Genge, A, Amato, AA, Shaibani, A, Jackson, CE, Kissel, JT, Wall, C, King, WM, Cupler, E, Lou, J-S, Ensrud, E, Tan, E, Goldstein, JM, Katz, J, Dimachkie, MM, Barohn, RJ, and Mozaffar, T. "Correspondence regarding: TDP-43 proteinopathy and motor neuron disease in chronic traumatic encephalopathy. J Neuropathol Exp Neurol 2010:69;918-29." J Neuropathol Exp Neurol 70, no. 1 (January 2011): 96-97. (Letter)  Full Text  Link to Item
    • Donofrio, PD, and Bedlack, R. "Historical controls in ALS trials: A high seas rescue?." Neurology 77, no. 10 (2011): 936-937.  Full Text
    • Simmons, BJ, Cohen, TJ, Bedlack, R, and Yao, T-P. "HDACs in skeletal muscle remodeling and neuromuscular disease." Handbook of Experimental Pharmacology 206 (2011): 79-101.  Full Text
    • Bedlack, RS, Wicks, P, Heywood, J, and Kasarskis, E. "Modifiable barriers to enrollment in American ALS research studies." Amyotroph Lateral Scler 11, no. 6 (December 2010): 502-507.  Full Text  Link to Item
    • Bedlack, RS. "Amyotrophic lateral sclerosis: current practice and future treatments." Curr Opin Neurol 23, no. 5 (October 2010): 524-529. (Review)  Full Text  Link to Item
    • Pastula, DM, Moore, DH, and Bedlack, RS. "Creatine for amyotrophic lateral sclerosis/motor neuron disease. (Published online)" Cochrane Database Syst Rev , no. 6 (June 16, 2010): CD005225-. (Review)  Full Text  Link to Item
    • Khishchenko, N, Allen, KD, Coffman, CJ, Kasarskis, EJ, Lindquist, JH, Morgenlander, JC, Norman, BB, Oddone, EZ, Rozear, MP, Sabet, A, Sams, L, and Bedlack, RS. "Time to diagnosis in the National Registry of Veterans with Amyotrophic Lateral Sclerosis." Amyotroph Lateral Scler 11, no. 1-2 (2010): 125-132.  Full Text  Link to Item
    • Schellenberg, K, Bedlack, R, and Tucci, D. "Roaring in the ears: Patulous eustachian tube in bulbar amyotrophic lateral sclerosis." Amyotrophic Lateral Sclerosis 11, no. 4 (2010): 395-396.  Full Text
    • Pastula, DM, Coffman, CJ, Allen, KD, Oddone, EZ, Kasarskis, EJ, Lindquist, JH, Morgenlander, JC, Norman, BB, Rozear, MP, Sams, LA, Sabet, A, and Bedlack, RS. "Factors associated with survival in the National Registry of Veterans with ALS." Amyotroph Lateral Scler 10, no. 5-6 (October 2009): 332-338.  Full Text  Link to Item
    • Qureshi, M, Bedlack, RS, and Cudkowicz, ME. "Lyme disease serology in amyotrophic lateral sclerosis." Muscle Nerve 40, no. 4 (October 2009): 626-628.  Full Text  Link to Item
    • Bedlack, RS, Pastula, DM, Hawes, J, and Heydt, D. "Open-label pilot trial of levetiracetam for cramps and spasticity in patients with motor neuron disease." Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 10, no. 4 (August 2009): 210-215.  Full Text
    • Bedlack, RS, Silani, V, and Cudkowicz, ME. "IPLEX and the telephone game: the difficulty in separating myth from reality on the internet." Amyotroph Lateral Scler 10, no. 3 (June 2009): 182-184.  Full Text  Link to Item
    • Cudkowicz, ME, Andres, PL, Macdonald, SA, Bedlack, RS, Choudry, R, Brown, RH, Zhang, H, Schoenfeld, DA, Shefner, J, Matson, S, Matson, WR, Ferrante, RJ, and Northeast ALS and National VA ALS Research Consortiums, . "Phase 2 study of sodium phenylbutyrate in ALS." Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 10, no. 2 (April 2009): 99-106.  Full Text
    • Bedlack, RS, and Aggarwal, S. "ALS UPDATE." Continuum: Lifelong Learning in Neurology 15 (February 2009): 83-110.  Full Text
    • Bedlack, R, and Hardiman, O. "ALSUntangled (ALSU): A scientific approach to off-label treatment options for people with ALS using tweets and twitters." Amyotrophic Lateral Sclerosis 10, no. 3 (2009): 129-130.  Full Text
    • Bedlack, RS, and Cudkowicz, ME. "Clinical trials in progressive neurological diseases. Recruitment, enrollment, retention and compliance." Front Neurol Neurosci 25 (2009): 144-151.  Full Text  Link to Item
    • Bedlack, RS, Pastula, DM, Welsh, E, Pulley, D, and Cudkowicz, ME. "Scrutinizing enrollment in ALS clinical trials: room for improvement?." Amyotroph Lateral Scler 9, no. 5 (October 2008): 257-265.  Full Text  Link to Item
    • Rosenfeld, J, King, RM, Jackson, CE, Bedlack, RS, Barohn, RJ, Dick, A, Phillips, LH, Chapin, J, Gelinas, DF, and Lou, J-S. "Creatine monohydrate in ALS: effects on strength, fatigue, respiratory status and ALSFRS." Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 9, no. 5 (October 2008): 266-272.  Full Text
    • Bedlack, RS, Maragakis, N, and Heiman-Patterson, T. "Lithium may slow progression of amyotrophic lateral sclerosis, but further study is needed." Proc Natl Acad Sci U S A 105, no. 16 (April 22, 2008): E17-. (Letter)  Full Text  Link to Item
    • Allen, KD, Kasarskis, EJ, Bedlack, RS, Rozear, MP, Morgenlander, JC, Sabet, A, Sams, L, Lindquist, JH, Harrelson, ML, Coffman, CJ, and Oddone, EZ. "The National Registry of Veterans with amyotrophic lateral sclerosis." Neuroepidemiology 30, no. 3 (2008): 180-190.  Full Text  Link to Item
    • Gordon, PH, Cheung, Y-K, Levin, B, Andrews, H, Doorish, C, MacArthur, RB, Montes, J, Bednarz, K, Florence, J, Rowin, J, Boylan, K, Mozaffar, T, Tandan, R, Mitsumoto, H, Kelvin, EA, Chapin, J, Bedlack, R, Rivner, M, McCluskey, LF, Pestronk, A, Graves, M, Sorenson, EJ, Barohn, R, Belsh, JM, Lou, J-S, Levine, T, Saperstein, D, Miller, RG, and Scelsa, SN. "A novel, efficient, randomized selection trial comparing combinations of drug therapy for ALS." Amyotrophic Lateral Sclerosis 9, no. 4 (2008): 212-222.  Full Text
    • Schmidt, S, Allen, KD, Loiacono, VT, Norman, B, Stanwyck, CL, Nord, KM, Williams, CD, Kasarskis, EJ, Kamel, F, McGuire, V, Nelson, LM, and Oddone, EZ. "Genes and Environmental Exposures in Veterans with Amyotrophic Lateral Sclerosis: the GENEVA study. Rationale, study design and demographic characteristics." Neuroepidemiology 30, no. 3 (January 2008): 191-204.  Full Text
    • Gwinn, K, Corriveau, RA, Mitsumoto, H, Bednarz, K, Brown, RH, Cudkowicz, M, Gordon, PH, Hardy, J, Kasarskis, EJ, Kaufmann, P, Miller, R, Sorenson, E, Tandan, R, Traynor, BJ, Nash, J, Sherman, A, Mailman, MD, Ostell, J, Bruijn, L, Cwik, V, Rich, SS, Singleton, A, Refolo, L, Andrews, J, Zhang, R, Conwit, R, Keller, MA, and ALS Research Group, . "Amyotrophic lateral sclerosis: an emerging era of collaborative gene discovery." Plos One 2, no. 12 (December 5, 2007): e1254-null.  Full Text
    • Gordon, PH, Moore, DH, Miller, RG, Florence, JM, Verheijde, JL, Doorish, C, Hilton, JF, Spitalny, GM, MacArthur, RB, Mitsumoto, H, Neville, HE, Boylan, K, Mozaffar, T, Belsh, JM, Ravits, J, Bedlack, RS, Graves, MC, McCluskey, LF, Barohn, RJ, Tandan, R, and Western ALS Study Group, . "Efficacy of minocycline in patients with amyotrophic lateral sclerosis: a phase III randomised trial." The Lancet. Neurology 6, no. 12 (December 2007): 1045-1053.  Full Text
    • Bedlack, RS, Traynor, BJ, and Cudkowicz, ME. "Emerging disease-modifying therapies for the treatment of motor neuron disease/amyotropic lateral sclerosis." Expert Opin Emerg Drugs 12, no. 2 (May 2007): 229-252. (Review)  Full Text  Link to Item
    • Tabbarah, K, Madden, J, and Bedlack, RS. "Dysarthria and dysphagia from light chain amyloidosis." Neurology 65, no. 10 (November 22, 2005): 1671-.  Full Text  Link to Item
    • "Working through the challenges of neuropathic pain." Emergency Medicine 37, no. 10 (October 1, 2005): 37-43. (Review)
    • Bedlack, RS, Simel, DL, Bosworth, H, Samsa, G, Tucker-Lipscomb, B, and Sanders, DB. "Quantitative myasthenia gravis score: assessment of responsiveness and longitudinal validity." Neurology 64, no. 11 (June 14, 2005): 1968-1970.  Full Text  Link to Item
    • Scherer, K, Bedlack, RS, and Simel, DL. "Does this patient have myasthenia gravis?." JAMA 293, no. 15 (April 20, 2005): 1906-1914. (Review)  Full Text  Link to Item
    • Bedlack, RS, Vu, T, Hammans, S, Sparr, SA, Myers, B, Morgenlander, J, and Hirano, M. "MNGIE neuropathy: five cases mimicking chronic inflammatory demyelinating polyneuropathy." Muscle Nerve 29, no. 3 (March 2004): 364-368.  Full Text  Link to Item
    • "Diagnosing and stabilizing acute neuropathies." Emergency Medicine 36, no. 1 (January 1, 2004): 15-27. (Review)
    • Brewer, R, Bedlack, R, and Massey, E. "Erratum to “Diabetic thoracic radiculopathy: an unusual cause of post-thoracotomy pain”[Pain 105 (2003) 221–223]." Pain 105, no. 3 (October 2003): 509-509.  Full Text
    • Bedlack, RS, Edelman, D, Gibbs, JW, Kelling, D, Strittmatter, W, Saunders, AM, and Morgenlander, J. "APOE genotype is a risk factor for neuropathy severity in diabetic patients." Neurology 60, no. 6 (March 25, 2003): 1022-1024.  Link to Item
    • Armon, C, Guiloff, RJ, and Bedlack, R. "Limitations of inferences from observational databases in amyotrophic lateral sclerosis: all that glitters is not gold." Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders : Official Publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 3, no. 3 (September 2002): 109-112. (Review)  Full Text
    • Bedlack, RS, and Sanders, DB. "On the concept of myasthenic crisis." J Clin Neuromuscul Dis 4, no. 1 (September 2002): 40-42.  Link to Item
    • Bedlack, RS, and Sanders, DB. "Steroid treatment for myasthenia gravis: steroids have an important role." Muscle & Nerve 25, no. 1 (January 2002): 117-121. (Review)  Full Text
    • Bedlack, RS, and Sanders, DB. "Steroids have an important role." Muscle & Nerve 25, no. 1 (January 2002): 117-121.  Full Text
    • Bedlack, RS, Strittmatter, WJ, and Morgenlander, JC. "Apolipoprotein E and neuromuscular disease: a critical review of the literature." Arch Neurol 57, no. 11 (November 2000): 1561-1565. (Review)  Link to Item
    • Bedlack, RS, Bertorini, TE, and Sanders, DB. "Hidden afterdischarges in slow channel congenital myasthenic syndrome." J Clin Neuromuscul Dis 1, no. 4 (June 2000): 186-190.  Link to Item
    • Bedlack, RS, and Sanders, DB. "How to handle myasthenic crisis. Essential steps in patient care." Postgrad Med 107, no. 4 (April 2000): 211-222. (Review)  Full Text  Link to Item
    • Ahearn, GS, Bedlack, RS, Price, DT, Robertson, CN, and Morgenlander, JC. "Transient lumbosacral polyradiculopathy after prostatectomy: association with spinal stenosis." South Med J 92, no. 8 (August 1999): 809-811.  Link to Item
    • Verma, A, Bedlack, RS, Radtke, RA, VanLandingham, KE, and Erwin, CW. "Succinylcholine induced hyperkalemia and cardiac arrest death related to an EEG study." J Clin Neurophysiol 16, no. 1 (January 1999): 46-50.  Link to Item
    • Bedlack, RS, Wei, MD, Fox, SH, Gross, E, and Loew, LM. "Distinct electric potentials in soma and neurite membranes." Neuron 13, no. 5 (November 1994): 1187-1193.  Full Text
    • Gross, E, Bedlack, RS, and Loew, LM. "Dual-wavelength ratiometric fluorescence measurement of the membrane dipole potential." Biophysical Journal 67, no. 1 (July 1994): 208-216.  Full Text
    • Bedlack, RS, Wei, M, and Loew, LM. "Localized membrane depolarizations and localized calcium influx during electric field-guided neurite growth." Neuron 9, no. 3 (September 1992): 393-403.  Full Text
    • Bedlack, R. "ALSUntangled 46: penicillin G/hydrocortisone(Published online)." Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration : 1-6.  Full Text

  • Conference Papers

    • Bedlack, RS, Pastuala, D, Welsh, E, Pulley, D, and Cudkowicz, M. "Scrutinizing enrollment in ALS clinical trials: Room for improvement?." March 11, 2008.  Link to Item
    • Bedlack, RS, and Torres, S. "Multifocal motor neuropathy with upper motor neuron signs." October 2006.  Link to Item
    • Bedlack, RS, Kelling, D, Edelman, D, Gibbs, JW, Strittmatter, W, and Morgenlander, J. "Apolipoprotein E genotype is a risk factor for diabetic neuropathy." December 2002.  Link to Item
    • Gross, E, Bedlack, RS, and Loew, LM. "Fluorescent imaging of membrane potential components." 1996.  Link to Item
    • BEDLACK, RS, WEI, MD, FOX, S, GROSS, E, and LOEW, LM. "ENDOGENOUS ELECTRIC-FIELDS WITHIN THE NEURONAL PLASMALEMMA - NONUNIFORMITIES SUGGESTING DIFFERENTIAL VOLTAGE-DEPENDENCE." February 1994.  Link to Item
    • GROSS, E, BEDLACK, RS, and LOEW, LM. "DUAL-WAVELENGTH RATIOMETRIC FLUORESCENCE MEASUREMENT OF THE MEMBRANE DIPOLE POTENTIAL." February 1994.  Link to Item
    • BEDLACK, RS, WEI, MD, and LOEW, LM. "ELECTRIC FIELD-BIASED N1E-115 GROWTH CONE FILOPODIAL PROTRUSIONS ARE INHIBITED BY VERAPAMIL." February 1993.  Link to Item

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