Richard Stanley Bedlack
Professor of Neurology
1. Investigator-initiated and multi-center clinical trials testing new treatments for amyotrophic lateral sclerosis and diabetic neuropathy.
2. Epidemiologic studies to better understand the causes and variability in prognosis of amyotrophic lateral sclerosis and diabetic neuropathy.
3. Basic science studies to develop novel biomarkers for amyotrophic lateral sclerosis.
2. Epidemiologic studies to better understand the causes and variability in prognosis of amyotrophic lateral sclerosis and diabetic neuropathy.
3. Basic science studies to develop novel biomarkers for amyotrophic lateral sclerosis.
Current Appointments & Affiliations
- Professor of Neurology, Neurology, Neuromuscular Disease, Neurology 2018
- Faculty Network Member of the Duke Institute for Brain Sciences, Duke Institute for Brain Sciences, University Institutes and Centers 2011
- Associate of the Duke Initiative for Science & Society, Duke Science & Society, Initiatives 2017
Contact Information
- 932 Morreene Rd Room234, Durham, NC 27705
- Duke Box 3333, Durham, NC 27710
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bedla001@mc.duke.edu
(919) 668-2839
- Background
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Education, Training, & Certifications
- EMG Fellow, Medicine, Duke University 1999 - 2000
- Neurology Resident, Medicine, Duke University 1996 - 1999
- Medical Intern, Medicine, Duke University 1995 - 1996
- M.D., University of Connecticut 1995
- Ph.D., University of Connecticut 1995
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Duke Appointment History
- Associate Professor of Neurology, Neurology, Neuromuscular Disease, Neurology 2011 - 2017
- Associate Professor of Medicine, Neurology, Clinical Science Departments 2006 - 2010
- Assistant Professor of Medicine, Neurology, Clinical Science Departments 2002 - 2006
- Associate in the Department of Medicine, Neurology, Clinical Science Departments 2000 - 2002
- Instructor, Temporary in the Department of Medicine, Neurology, Clinical Science Departments 2000
- Recognition
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In the News
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NOV 17, 2017 Duke Magazine -
MAY 23, 2017 Clinical Practice Today -
MAR 8, 2017 Duke Health News -
OCT 24, 2016 NPRs All Things Considered -
JUN 15, 2016 The Wall Street Journal -
NOV 16, 2015 The News & Observer -
AUG 13, 2015 -
AUG 13, 2015 ABC 11 -
AUG 13, 2015 Durham Herald-Sun -
FEB 20, 2015 WTVD -
NOV 18, 2014 -
AUG 29, 2014 -
APR 23, 2014 Ivanhoe Broadcast News -
MAR 10, 2014 The News & Observer
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- Research
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Selected Grants
- A Pilot Trial of Triheptanoin for People with Amyotrophic Lateral Sclerosis (PALS) awarded by Ultragenyx Pharmaceutical 2018 - 2020
- CYTO-5022 awarded by Cytokinetics, Inc. 2017 - 2019
- ALS Telemedicine awarded by Amyotrophic Lateral Sclerosis Association 2018 - 2019
- The Duke ALS Association Certified Center awarded by Amyotrophic Lateral Sclerosis Association 2018 - 2019
- Retigabine and or Ezogabine in ALS awarded by GlaxoSmithKline 2015 - 2018
- Neuraltus NP001 awarded by Neuraltus Pharmaceuticals, Inc 2016 - 2018
- Integrated Genomics in Clinical ALS (GTAC) awarded by Columbia University 2016 - 2018
- Clinical Research in ALS & Related Disorders for Therapeutic Development (CREATE) awarded by University of Miami 2014 - 2018
- Open Label Cytokinetics (CY4031) awarded by Cytokinetics, Inc. 2016 - 2018
- Tirasemtiv in ALS awarded by Cytokinetics, Inc. 2015 - 2018
- Diaphragm Pacer Study awarded by Synapse Biomedical, Inc 2013 - 2018
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Statland, Jeffrey M., Dan Moore, Yunxia Wang, Maureen Walsh, Tahseen Mozaffar, Lauren Elman, Sharon P. Nations, et al. “Rasagiline for amyotrophic lateral sclerosis: A randomized, controlled trial..” Muscle & Nerve 59, no. 2 (February 2019): 201–7. https://doi.org/10.1002/mus.26335.Full Text
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Bedlack, R. “ALSUntangled 44: curcumin.” Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 19, no. 7–8 (October 2, 2018): 623–29. https://doi.org/10.1080/21678421.2018.1440738.Full Text
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Harrison, D., P. Mehta, M. A. van Es, E. Stommel, V. E. Drory, B. Nefussy, L. H. van den Berg, J. Crayle, and R. Bedlack. ““ALS reversals”: demographics, disease characteristics, treatments, and co-morbidities.” Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 19, no. 7–8 (October 2, 2018): 495–99. https://doi.org/10.1080/21678421.2018.1457059.Full Text
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Rice, V., R. Bedlack, R. Bowser, P. Wicks, D. Forshew, S. Kolb, J. Rothstein, et al. “ALSUntangled 43: copper.” Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 19, no. 5–6 (July 3, 2018): 472–76. https://doi.org/10.1080/21678421.2017.1406733.Full Text
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Bedlack, Richard, and Richard ALSUntangled Group. “ALSUntangled 42: Elysium health's "basis"..” Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration 19, no. 3–4 (May 2018): 317–19. https://doi.org/10.1080/21678421.2017.1373978.Full Text
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Earl, Damien E., Aaron I. Loochtan, and Richard S. Bedlack. “Refractory myasthenia gravis exacerbation triggered By pembrolizumab..” Muscle & Nerve 57, no. 4 (April 2018): E120–21. https://doi.org/10.1002/mus.26021.Full Text
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Nicolas, Aude, Kevin P. Kenna, Alan E. Renton, Nicola Ticozzi, Faraz Faghri, Ruth Chia, Janice A. Dominov, et al. “Genome-wide Analyses Identify KIF5A as a Novel ALS Gene..” Neuron 97, no. 6 (March 2018): 1268-1283.e6. https://doi.org/10.1016/j.neuron.2018.02.027.Full Text
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ALSUntangled Group, Cagla. “ALSUntangled 41: "Eric Is Winning"..” Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration 19, no. 1–2 (February 2018): 157–60. https://doi.org/10.1080/21678421.2017.1350532.Full Text
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Horton, D Kevin, Shannon Graham, Reshma Punjani, Grete Wilt, Wendy Kaye, Kimberly Maginnis, Lauren Webb, et al. “A spatial analysis of amyotrophic lateral sclerosis (ALS) cases in the United States and their proximity to multidisciplinary ALS clinics, 2013..” Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration 19, no. 1–2 (February 2018): 126–33. https://doi.org/10.1080/21678421.2017.1406953.Full Text
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Bedlack, R. “ALSUntangled 46: penicillin G/hydrocortisone.” Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, January 1, 2018. https://doi.org/10.1080/21678421.2018.1512704.Full Text
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Bedlack, R. “ALSUntangled No. 47: RT001.” Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, January 1, 2018. https://doi.org/10.1080/21678421.2018.1549531.Full Text
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Woolley, Susan, Ray Goetz, Pam Factor-Litvak, Jennifer Murphy, Jonathan Hupf, Catherine Lomen-Hoerth, Howard Andrews, et al. “Longitudinal Screening Detects Cognitive Stability and Behavioral Deterioration in ALS Patients..” Behavioural Neurology 2018 (January 2018). https://doi.org/10.1155/2018/5969137.Full Text
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Bedlack, Richard. “Perspective: Untangling the ALS X-Files..” Nature 550, no. 7676 (October 2017). https://doi.org/10.1038/550s122a.Full Text
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ALSUntangled Group, A. A. “ALSUntangled No. 37: Inosine..” Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration 18, no. 3–4 (May 2017): 309–12. https://doi.org/10.1080/21678421.2016.1223270.Full Text
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ALSUNTANGLED GROUP, H. “ALSUntangled No. 36: Accilion..” Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration 18, no. 1–2 (February 2017): 142–47. https://doi.org/10.1080/21678421.2016.1215400.Full Text
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ALSUntangled Group, Gail. “ALSUntangled 38: L-serine..” Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration 18, no. 1–2 (February 2017): 148–51. https://doi.org/10.1080/21678421.2016.1250353.Full Text
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Mukherjee, Nisha, Shan McBurney-Lin, Anthony Kuo, Richard Bedlack, and Henry Tseng. “Retinal thinning in amyotrophic lateral sclerosis patients without ophthalmic disease..” Plos One 12, no. 9 (January 2017). https://doi.org/10.1371/journal.pone.0185242.Full Text
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Nieves, Jeri W., Chris Gennings, Pam Factor-Litvak, Jonathan Hupf, Jessica Singleton, Valerie Sharf, Björn Oskarsson, et al. “Association Between Dietary Intake and Function in Amyotrophic Lateral Sclerosis..” Jama Neurology 73, no. 12 (December 2016): 1425–32. https://doi.org/10.1001/jamaneurol.2016.3401.Full Text
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ALSUntangled Group, Sanjay. “ALSUntangled No. 35: Hyperbaric Oxygen Therapy..” Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration 17, no. 7–8 (October 2016): 622–24. https://doi.org/10.3109/21678421.2016.1172818.Full Text
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“ALSUntangled No. 34: GM604..” Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration 17, no. 7–8 (October 2016): 617–21. https://doi.org/10.3109/21678421.2016.1164940.Full Text
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Lee, Caroline M., Jason D. Lee, Lisa D. Hobson-Webb, Richard S. Bedlack, and Joseph K. Salama. “Treatment of Thymoma-Associated Myasthenia Gravis With Stereotactic Body Radiotherapy: A Case Report..” Annals of Internal Medicine 165, no. 4 (August 2016): 300–301. https://doi.org/10.7326/l15-0469.Full Text
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Bedlack, Richard S., Timothy Vaughan, Paul Wicks, Jamie Heywood, Ervin Sinani, Roger Selsov, Eric A. Macklin, David Schoenfeld, Merit Cudkowicz, and Alex Sherman. “How common are ALS plateaus and reversals?.” Neurology 86, no. 9 (March 2016): 808–12. https://doi.org/10.1212/WNL.0000000000002251.Full Text
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Murphy, Jennifer, Pam Factor-Litvak, Raymond Goetz, Catherine Lomen-Hoerth, Peter L. Nagy, Jonathan Hupf, Jessica Singleton, et al. “Cognitive-behavioral screening reveals prevalent impairment in a large multicenter ALS cohort..” Neurology 86, no. 9 (March 2016): 813–20. https://doi.org/10.1212/WNL.0000000000002305.Full Text
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Karam, Chafic Y., Sabrina Paganoni, Nanette Joyce, Gregory T. Carter, and Richard Bedlack. “Palliative Care Issues in Amyotrophic Lateral Sclerosis: An Evidenced-Based Review..” The American Journal of Hospice & Palliative Care 33, no. 1 (February 2016): 84–92. https://doi.org/10.1177/1049909114548719.Full Text
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Bedlack, Richard S., Nanette Joyce, Gregory T. Carter, Sabrina Paganoni, and Chafic Karam. “Complementary and Alternative Therapies in Amyotrophic Lateral Sclerosis..” Neurologic Clinics 33, no. 4 (November 2015): 909–36. https://doi.org/10.1016/j.ncl.2015.07.008.Full Text
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Miller, Robert G., Gilbert Block, Jonathan S. Katz, Richard J. Barohn, Vidhya Gopalakrishnan, Merit Cudkowicz, Jane R. Zhang, et al. “Randomized phase 2 trial of NP001-a novel immune regulator: Safety and early efficacy in ALS..” Neurology(R) Neuroimmunology & Neuroinflammation 2, no. 3 (June 2015). https://doi.org/10.1212/NXI.0000000000000100.Full Text
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Cirulli, Elizabeth T., Brittany N. Lasseigne, Slavé Petrovski, Peter C. Sapp, Patrick A. Dion, Claire S. Leblond, Julien Couthouis, et al. “Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways..” Science 347, no. 6229 (March 27, 2015): 1436–41. https://doi.org/10.1126/science.aaa3650.Full Text Link to Item
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ALSUntangled Group, J. “ALSUntangled: introducing The Table of Evidence..” Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration 16, no. 1–2 (March 2015): 142–45. https://doi.org/10.3109/21678421.2014.987476.Full Text
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ALSUntangled Group, F. “ALSUntangled No. 29: MitoQ..” Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration 16, no. 5–6 (January 2015): 427–29. https://doi.org/10.3109/21678421.2015.1050897.Full Text
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Paganoni, Sabrina, Chafic Karam, Nanette Joyce, Richard Bedlack, and Gregory T. Carter. “Comprehensive rehabilitative care across the spectrum of amyotrophic lateral sclerosis..” Neurorehabilitation 37, no. 1 (January 2015): 53–68. https://doi.org/10.3233/NRE-151240.Full Text
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ALSUntangled Group, Gregory T. “ALSUntangled No. 26: lunasin..” Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration 15, no. 7–8 (December 2014): 622–26. https://doi.org/10.3109/21678421.2014.959297.Full Text
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Mitsumoto, Hiroshi, Pam Factor-Litvak, Howard Andrews, Raymond R. Goetz, Leslie Andrews, Judith G. Rabkin, Martin McElhiney, et al. “ALS Multicenter Cohort Study of Oxidative Stress (ALS COSMOS): study methodology, recruitment, and baseline demographic and disease characteristics..” Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration 15, no. 3–4 (June 2014): 192–203. https://doi.org/10.3109/21678421.2013.864312.Full Text
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Rabourn, Jess, and Richard S. Bedlack. “SAPs: a different perspective..” The American Journal of Bioethics : Ajob 14, no. 11 (January 2014): 19–20. https://doi.org/10.1080/15265161.2014.957621.Full Text
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ALSUntangled Group, Julie A., Christina Fournier, Bedlack Bedlack, Orla Hardiman, Terry Heiman-Patterson, Laurie Gutmann, Mark Bromberg, et al. “ALS Untangled No. 20: the Deanna protocol..” Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration 14, no. 4 (May 2, 2013): 319–23. https://doi.org/10.3109/21678421.2013.788405.Full Text
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Chad, David A., Lewis P. Rowland, Carmel Armon, Richard Bedlack, Heather Durham, Pam Factor-Litvak, Terry Heiman-Patterson, et al. “Peer recommendations on how to improve clinical research, and Conference wrap-up..” Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration 14 Suppl 1 (May 2013): 67–73. https://doi.org/10.3109/21678421.2013.778605.Full Text
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Sherman, Alexander V., Amelie K. Gubitz, Ammar Al-Chalabi, Richard Bedlack, James Berry, Robin Conwit, Brent T. Harris, et al. “Infrastructure resources for clinical research in amyotrophic lateral sclerosis..” Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration 14 Suppl 1 (May 2013): 53–61. https://doi.org/10.3109/21678421.2013.779058.Full Text
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Pastula, Daniel M., Dan H. Moore, and Richard S. Bedlack. “Creatine for amyotrophic lateral sclerosis/motor neuron disease..” Cochrane Database Syst Rev 12 (December 12, 2012). https://doi.org/10.1002/14651858.CD005225.pub3.Full Text Link to Item
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ALSUntangled Group, James D. “ALS untangled No. 17: "when ALS is lyme"..” Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 13, no. 5 (September 2012): 487–91. https://doi.org/10.3109/17482968.2012.717796.Full Text
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Scherer, Katalin, and Richard S. Bedlack. “Diaphragm pacing in amyotrophic lateral sclerosis: a literature review..” Muscle & Nerve 46, no. 1 (July 2012): 1–8. https://doi.org/10.1002/mus.23419.Full Text
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ALSUntangled Group, S. W. “ALSUntangled No. 16: cannabis..” Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 13, no. 4 (June 2012): 400–404. https://doi.org/10.3109/17482968.2012.687264.Full Text
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Kamel, Freya, David M. Umbach, Richard S. Bedlack, Marie Richards, Mary Watson, Michael C. R. Alavanja, Aaron Blair, Jane A. Hoppin, Silke Schmidt, and Dale P. Sandler. “Pesticide exposure and amyotrophic lateral sclerosis..” Neurotoxicology 33, no. 3 (June 2012): 457–62. https://doi.org/10.1016/j.neuro.2012.04.001.Full Text
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ALSUntangled Group, Richard S. “ALSUntangled 15: coconut Oil..” Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 13, no. 3 (May 2012): 328–30. https://doi.org/10.3109/17482968.2012.671629.Full Text
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Caulfield, Timothy, Amy Zarzeczny, and Amy Toronto Stem Cell Working Group. “Stem cell tourism and Canadian family physicians..” Canadian Family Physician Medecin De Famille Canadien 58, no. 4 (April 2012): 365-e185.
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Bedlack, Richard S. “Compassionate use of stem cells for ALS: popovers and hot air..” Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 12, no. 5 (September 2011): 313–14. https://doi.org/10.3109/17482968.2011.583743.Full Text
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Donofrio, Peter D., and Richard Bedlack. “Historical controls in ALS trials: a high seas rescue?.” Neurology 77, no. 10 (September 2011): 936–37. https://doi.org/10.1212/wnl.0b013e31822cfcb6.Full Text
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Bedlack, Richard S., Angela Genge, Anthony A. Amato, Aziz Shaibani, Carlayne E. Jackson, John T. Kissel, Cheryl Wall, et al. “Correspondence regarding: TDP-43 proteinopathy and motor neuron disease in chronic traumatic encephalopathy. J Neuropathol Exp Neurol 2010:69;918-29..” Journal of Neuropathology and Experimental Neurology 70, no. 1 (January 2011): 96–97. https://doi.org/10.1097/nen.0b013e318204782b.Full Text
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Simmons, Bryan J., Todd J. Cohen, Richard Bedlack, and Tso-Pang Yao. “HDACs in skeletal muscle remodeling and neuromuscular disease..” Handbook of Experimental Pharmacology 206 (January 2011): 79–101. https://doi.org/10.1007/978-3-642-21631-2_5.Full Text
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Bedlack, Richard S., Paul Wicks, James Heywood, and Edward Kasarskis. “Modifiable barriers to enrollment in American ALS research studies..” Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 11, no. 6 (December 2010): 502–7. https://doi.org/10.3109/17482968.2010.484494.Full Text
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Bedlack, Richard S. “Amyotrophic lateral sclerosis: current practice and future treatments..” Current Opinion in Neurology 23, no. 5 (October 2010): 524–29. https://doi.org/10.1097/wco.0b013e32833c7ac2.Full Text
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Schellenberg, Kerri, Richard Bedlack, and Debara Tucci. “Roaring in the ears: patulous Eustachian tube in bulbar amyotrophic lateral sclerosis..” Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 11, no. 4 (August 2010): 395–96. https://doi.org/10.3109/17482960903501931.Full Text
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Khishchenko, Natan, Kelli D. Allen, Cynthia J. Coffman, Edward J. Kasarskis, Jennifer H. Lindquist, Joel C. Morgenlander, Barbara B. Norman, et al. “Time to diagnosis in the National Registry of Veterans with Amyotrophic Lateral Sclerosis..” Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 11, no. 1–2 (January 2010): 125–32. https://doi.org/10.3109/17482960802572681.Full Text
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Pastula, Daniel M., Dan H. Moore, and Richard S. Bedlack. “Creatine for amyotrophic lateral sclerosis/motor neuron disease..” The Cochrane Database of Systematic Reviews, no. 6 (January 2010). https://doi.org/10.1002/14651858.cd005225.pub2.Full Text
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Pastula, Daniel M., Cynthia J. Coffman, Kelli D. Allen, Eugene Z. Oddone, Edward J. Kasarskis, Jennifer H. Lindquist, Joel C. Morgenlander, et al. “Factors associated with survival in the National Registry of Veterans with ALS..” Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 10, no. 5–6 (October 2009): 332–38. https://doi.org/10.3109/17482960802320545.Full Text
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Qureshi, Muddasir, Richard S. Bedlack, and Merit E. Cudkowicz. “Lyme disease serology in amyotrophic lateral sclerosis..” Muscle & Nerve 40, no. 4 (October 2009): 626–28. https://doi.org/10.1002/mus.21438.Full Text
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Bedlack, Richard S., Daniel M. Pastula, Jodi Hawes, and Debra Heydt. “Open-label pilot trial of levetiracetam for cramps and spasticity in patients with motor neuron disease..” Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 10, no. 4 (August 2009): 210–15. https://doi.org/10.1080/17482960802430773.Full Text
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Bedlack, Richard S., Vincenzo Silani, and Merit Ester Cudkowicz. “IPLEX and the telephone game: the difficulty in separating myth from reality on the internet..” Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 10, no. 3 (June 2009): 182–84. https://doi.org/10.1080/17482960802673059.Full Text
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Bedlack, Richard, and Orla Hardiman. “ALSUntangled (ALSU): a scientific approach to off-label treatment options for people with ALS using tweets and twitters..” Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 10, no. 3 (June 2009): 129–30. https://doi.org/10.1080/17482960903015986.Full Text
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Cudkowicz, Merit E., Patricia L. Andres, Sally A. Macdonald, Richard S. Bedlack, Rabia Choudry, Robert H. Brown, Hui Zhang, et al. “Phase 2 study of sodium phenylbutyrate in ALS..” Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 10, no. 2 (April 2009): 99–106. https://doi.org/10.1080/17482960802320487.Full Text
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Bedlack, R. S., and S. Aggarwal. “Als update: Signs of progress, easons for hope.” Continuum Lifelong Learning in Neurology 15, no. 1 (January 1, 2009): 83–110. https://doi.org/10.1212/01.CON.0000300009.02717.a2.Full Text
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Bedlack, Richard S., and Merit E. Cudkowicz. “Clinical trials in progressive neurological diseases. Recruitment, enrollment, retention and compliance..” Frontiers of Neurology and Neuroscience 25 (January 2009): 144–51. https://doi.org/10.1159/000209493.Full Text
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Bedlack, Richard S., Daniel M. Pastula, Emily Welsh, Darlene Pulley, and Merit E. Cudkowicz. “Scrutinizing enrollment in ALS clinical trials: room for improvement?.” Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 9, no. 5 (October 2008): 257–65. https://doi.org/10.1080/17482960802195913.Full Text
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Rosenfeld, Jeffrey, Ruth M. King, Carlayne E. Jackson, Richard S. Bedlack, Richard J. Barohn, Arthur Dick, Lawrence H. Phillips, John Chapin, Deborah F. Gelinas, and Jau-Shin Lou. “Creatine monohydrate in ALS: effects on strength, fatigue, respiratory status and ALSFRS..” Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 9, no. 5 (October 2008): 266–72. https://doi.org/10.1080/17482960802028890.Full Text
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Gordon, Paul H., Ying-Kuen Cheung, Bruce Levin, Howard Andrews, Carolyn Doorish, Robert B. Macarthur, Jacqueline Montes, et al. “A novel, efficient, randomized selection trial comparing combinations of drug therapy for ALS..” Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 9, no. 4 (August 2008): 212–22. https://doi.org/10.1080/17482960802195632.Full Text
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Bedlack, Richard S., Nicholas Maragakis, and Terry Heiman-Patterson. “Lithium may slow progression of amyotrophic lateral sclerosis, but further study is needed..” Proceedings of the National Academy of Sciences of the United States of America 105, no. 16 (April 16, 2008). https://doi.org/10.1073/pnas.0801762105.Full Text
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Allen, K. D., E. J. Kasarskis, R. S. Bedlack, M. P. Rozear, J. C. Morgenlander, A. Sabet, L. Sams, et al. “The National Registry of Veterans with amyotrophic lateral sclerosis..” Neuroepidemiology 30, no. 3 (January 2008): 180–90. https://doi.org/10.1159/000126910.Full Text
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Schmidt, Silke, Kelli D. Allen, Valerie T. Loiacono, Barbara Norman, Catherine L. Stanwyck, Kristina M. Nord, Christina D. Williams, et al. “Genes and Environmental Exposures in Veterans with Amyotrophic Lateral Sclerosis: the GENEVA study. Rationale, study design and demographic characteristics..” Neuroepidemiology 30, no. 3 (January 2008): 191–204. https://doi.org/10.1159/000126911.Full Text
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Gwinn, Katrina, Roderick A. Corriveau, Hiroshi Mitsumoto, Kate Bednarz, Robert H. Brown, Merit Cudkowicz, Paul H. Gordon, et al. “Amyotrophic lateral sclerosis: an emerging era of collaborative gene discovery..” Plos One 2, no. 12 (December 5, 2007). https://doi.org/10.1371/journal.pone.0001254.Full Text
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Gordon, Paul H., Dan H. Moore, Robert G. Miller, Julaine M. Florence, Joseph L. Verheijde, Carolyn Doorish, Joan F. Hilton, et al. “Efficacy of minocycline in patients with amyotrophic lateral sclerosis: a phase III randomised trial..” Lancet Neurol 6, no. 12 (December 2007): 1045–53. https://doi.org/10.1016/S1474-4422(07)70270-3.Full Text Link to Item
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Bedlack, Richard S., Bryan J. Traynor, and Merit E. Cudkowicz. “Emerging disease-modifying therapies for the treatment of motor neuron disease/amyotropic lateral sclerosis..” Expert Opinion on Emerging Drugs 12, no. 2 (May 2007): 229–52. https://doi.org/10.1517/14728214.12.2.229.Full Text
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Tabbarah, Khalid, John Madden, and Richard S. Bedlack. “Dysarthria and dysphagia from light chain amyloidosis..” Neurology 65, no. 10 (November 2005). https://doi.org/10.1212/01.wnl.0000182295.32791.e5.Full Text
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Scherer, K., and R. S. Bedlack. “Working through the challenges of neuropathic pain.” Emergency Medicine 37, no. 10 (October 1, 2005): 37–43.
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Bedlack, R. S., D. L. Simel, H. Bosworth, G. Samsa, B. Tucker-Lipscomb, and D. B. Sanders. “Quantitative myasthenia gravis score: assessment of responsiveness and longitudinal validity..” Neurology 64, no. 11 (June 14, 2005): 1968–70. https://doi.org/10.1212/01.WNL.0000163988.28892.79.Full Text Link to Item
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Scherer, Katalin, Richard S. Bedlack, and David L. Simel. “Does this patient have myasthenia gravis?.” Jama 293, no. 15 (April 2005): 1906–14. https://doi.org/10.1001/jama.293.15.1906.Full Text
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Bedlack, Richard S., Tuan Vu, Simon Hammans, Steven A. Sparr, Bennett Myers, Joel Morgenlander, and Michio Hirano. “MNGIE neuropathy: five cases mimicking chronic inflammatory demyelinating polyneuropathy..” Muscle & Nerve 29, no. 3 (March 2004): 364–68. https://doi.org/10.1002/mus.10546.Full Text
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Burke, P., and R. S. Bedlack. “Diagnosing and stabilizing acute neuropathies.” Emergency Medicine 36, no. 1 (January 1, 2004): 15–27.
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Bedlack, R. S., D. Edelman, J. W. Gibbs, D. Kelling, W. Strittmatter, A. M. Saunders, and J. Morgenlander. “APOE genotype is a risk factor for neuropathy severity in diabetic patients..” Neurology 60, no. 6 (March 2003): 1022–24. https://doi.org/10.1212/01.wnl.0000056689.50682.94.Full Text
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Brewer, R., R. Bedlack, and E. Massey. “Erratum: Diabetic thoracic radiculopathy: An unusual cause of post-thoracotomy pain (Pain (2003) 105 (221-223)).” Pain 105, no. 3 (January 1, 2003). https://doi.org/10.1016/j.pain.2003.09.001.Full Text
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Armon, Carmel, Roberto J. Guiloff, and Richard Bedlack. “Limitations of inferences from observational databases in amyotrophic lateral sclerosis: all that glitters is not gold..” Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders : Official Publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 3, no. 3 (September 2002): 109–12. https://doi.org/10.1080/146608202760834094.Full Text
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Bedlack, Richard S., and Donald B. Sanders. “On the concept of myasthenic crisis..” Journal of Clinical Neuromuscular Disease 4, no. 1 (September 2002): 40–42.
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Bedlack, R. S., and D. B. Sanders. “Steroids have an important role.” Muscle and Nerve 25, no. 1 (January 1, 2002): 117–21. https://doi.org/10.1002/mus.1221.Full Text
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Bedlack, Richard S., and Donald B. Sanders. “Steroid treatment for myasthenia gravis: steroids have an important role..” Muscle & Nerve 25, no. 1 (January 2002): 117–21. https://doi.org/10.1002/mus.1221.Full Text
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Bedlack, R. S., W. J. Strittmatter, and J. C. Morgenlander. “Apolipoprotein E and neuromuscular disease: a critical review of the literature..” Archives of Neurology 57, no. 11 (November 2000): 1561–65. https://doi.org/10.1001/archneur.57.11.1561.Full Text
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Bedlack, R. S., T. E. Bertorini, and D. B. Sanders. “Hidden afterdischarges in slow channel congenital myasthenic syndrome..” Journal of Clinical Neuromuscular Disease 1, no. 4 (June 2000): 186–90.
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Bedlack, R. S., and D. B. Sanders. “How to handle myasthenic crisis. Essential steps in patient care..” Postgraduate Medicine 107, no. 4 (April 2000): 211–22. https://doi.org/10.3810/pgm.2000.04.1003.Full Text
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Ahearn, G. S., R. S. Bedlack, D. T. Price, C. N. Robertson, and J. C. Morgenlander. “Transient lumbosacral polyradiculopathy after prostatectomy: association with spinal stenosis..” Southern Medical Journal 92, no. 8 (August 1999): 809–11.
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Verma, A., R. S. Bedlack, R. A. Radtke, K. E. VanLandingham, and C. W. Erwin. “Succinylcholine induced hyperkalemia and cardiac arrest death related to an EEG study..” Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society 16, no. 1 (January 1999): 46–50. https://doi.org/10.1097/00004691-199901000-00004.Full Text
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Bedlack, R. S., M. D. Wei, S. H. Fox, E. Gross, and L. M. Loew. “Distinct electric potentials in soma and neurite membranes..” Neuron 13, no. 5 (November 1994): 1187–93. https://doi.org/10.1016/0896-6273(94)90056-6.Full Text
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Gross, E., R. S. Bedlack, and L. M. Loew. “Dual-wavelength ratiometric fluorescence measurement of the membrane dipole potential..” Biophys J 67, no. 1 (July 1994): 208–16. https://doi.org/10.1016/S0006-3495(94)80471-0.Full Text Link to Item
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Bedlack, R. S., M. Wei, and L. M. Loew. “Localized membrane depolarizations and localized calcium influx during electric field-guided neurite growth..” Neuron 9, no. 3 (September 1992): 393–403. https://doi.org/10.1016/0896-6273(92)90178-g.Full Text
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Bedlack, R. S., Paul Wicks, Timothy Vaughan, Alicia Opie, Rebecca Blum, Amanda Dios, and Ghazaleh Sadri-Vakili. “Lunasin does not slow ALS progression: results of an open-label, single-center, hybrid-virtual 12-month trial..” Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, January 21, 2019, 1–9. https://doi.org/10.1080/21678421.2018.1556698.Full Text
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Pastula, Daniel M., Dan H. Moore, and Richard S. Bedlack. “Creatine for amyotrophic lateral sclerosis/motor neuron disease.” Cochrane Database of Systematic Reviews, n.d. https://doi.org/10.1002/14651858.cd005225.pub3.Full Text
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Conference Papers
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Bedlack, Richard S., Daniel Pastuala, Elizabeth Welsh, Darlene Pulley, and Merit Cudkowicz. “Scrutinizing enrollment in ALS clinical trials: Room for improvement?.” In Neurology, 70:A344–A344. LIPPINCOTT WILLIAMS & WILKINS, 2008.Link to Item
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Bedlack, R. S., and S. Torres. “Multifocal motor neuropathy with upper motor neuron signs.” In Muscle & Nerve, 34:514–514. JOHN WILEY & SONS INC, 2006.Link to Item
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Bedlack, R. S., D. Kelling, D. Edelman, J. W. Gibbs, W. Strittmatter, and J. Morgenlander. “Apolipoprotein E genotype is a risk factor for diabetic neuropathy.” In Annals of Neurology, 52:866–866. WILEY-LISS, 2002.Link to Item
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Gross, E., R. S. Bedlack, and L. M. Loew. “Fluorescent imaging of membrane potential components.” In Analytical Use of Fluorescent Probes in Oncology, edited by E. Kohen and J. G. Hirschberg, 286:249–56. PLENUM PRESS DIV PLENUM PUBLISHING CORP, 1996.Link to Item
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BEDLACK, R. S., M. D. WEI, S. FOX, E. GROSS, and L. M. LOEW. “ENDOGENOUS ELECTRIC-FIELDS WITHIN THE NEURONAL PLASMALEMMA - NONUNIFORMITIES SUGGESTING DIFFERENTIAL VOLTAGE-DEPENDENCE.” In Biophysical Journal, 66:A387–A387. BIOPHYSICAL SOCIETY, 1994.Link to Item
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GROSS, E., R. S. BEDLACK, and L. M. LOEW. “DUAL-WAVELENGTH RATIOMETRIC FLUORESCENCE MEASUREMENT OF THE MEMBRANE DIPOLE POTENTIAL.” In Biophysical Journal, 66:A387–A387. BIOPHYSICAL SOCIETY, 1994.Link to Item
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BEDLACK, R. S., M. D. WEI, and L. M. LOEW. “ELECTRIC FIELD-BIASED N1E-115 GROWTH CONE FILOPODIAL PROTRUSIONS ARE INHIBITED BY VERAPAMIL.” In Biophysical Journal, 64:A101–A101. BIOPHYSICAL SOCIETY, 1993.Link to Item
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