Overview
2. Epidemiologic studies to better understand the causes and variability in prognosis of amyotrophic lateral sclerosis and diabetic neuropathy.
3. Basic science studies to develop novel biomarkers for amyotrophic lateral sclerosis.
Current Appointments & Affiliations
Stewart, Hughes and Wendt Distinguished Professor
·
2023 - Present
Neurology, Neuromuscular Disease,
Neurology
Professor of Neurology
·
2018 - Present
Neurology, Neuromuscular Disease,
Neurology
Faculty Network Member of the Duke Institute for Brain Sciences
·
2011 - Present
Duke Institute for Brain Sciences,
University Institutes and Centers
Associate of the Duke Initiative for Science & Society
·
2017 - Present
Duke Science & Society,
University Initiatives & Academic Support Units
Recent Publications
ALS Motor Observational Telemedicine Objective Rasch-Built Assessment: A Quantitative Scale for the Era of Teleneurology.
Journal Article Neurol Clin Pract · April 2025 BACKGROUND AND OBJECTIVES: Telemedicine has become a mainstay of ALS clinical care, but there is currently no standardized approach for assessing and tracking changes to the neurologic examination in this format. The goal of this study was to create a stan ... Full text Link to item CiteOverstating harms can have consequences.
Journal Article Brain · February 5, 2025 Full text Link to item CiteEfficacy and Safety of Zilucoplan in Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial.
Journal Article JAMA Netw Open · February 3, 2025 IMPORTANCE: The etiology of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease, is unknown. However, neuroinflammation and complement activation may play a role in disease progression. OBJECTIVE: To determine the effects of zilucoplan, ... Full text Link to item CiteRecent Grants
Pridopine EAP 2 (Clinical Site Agreement)
ResearchPrincipal Investigator · Awarded by Massachusetts General Hospital · 2024 - 2027An Intermediate Expanded Access Protocol (EAP) with CNM-Au8 for Amyotrophic Lateral Sclerosis
ResearchPrincipal Investigator · Awarded by Clene Nanomedicine Inc. · 2024 - 2026Pilot Trial to Investigate The Safety, Tolerability and Preliminary Efficacy of BL-001 Probiotic in People with ALS
Clinical TrialPrincipal Investigator · Awarded by Hop On A Cure · 2024 - 2026View All Grants
Education, Training & Certifications
University of Connecticut ·
1995
M.D.
University of Connecticut ·
1995
Ph.D.