Overview
2. Epidemiologic studies to better understand the causes and variability in prognosis of amyotrophic lateral sclerosis and diabetic neuropathy.
3. Basic science studies to develop novel biomarkers for amyotrophic lateral sclerosis.
Current Appointments & Affiliations
Stewart, Hughes and Wendt Distinguished Professor
·
2023 - Present
Neurology, Neuromuscular Disease,
Neurology
Professor of Neurology
·
2018 - Present
Neurology, Neuromuscular Disease,
Neurology
Faculty Network Member of the Duke Institute for Brain Sciences
·
2011 - Present
Duke Institute for Brain Sciences,
University Institutes and Centers
Associate of the Duke Initiative for Science & Society
·
2017 - Present
Duke Science & Society,
University Initiatives & Academic Support Units
Recent Publications
ALSUntangled #79: alpha-lipoic acid.
Journal Article Amyotroph Lateral Scler Frontotemporal Degener · February 2026 Alpha-lipoic acid (ALA) is a naturally occurring fatty acid. It serves as an essential cofactor for enzymatic reactions in mitochondrial energy production, is a potent antioxidant and has anti-inflammatory effects, which are plausible mechanisms in slowing ... Full text Link to item CiteToward a “green” brain health agenda: establishing short- and long-term goals for the field of neurology in a changing climate
Journal Article Frontiers in Neurology · January 1, 2026 The global burden of neurological disease is rising amid an aging population and accelerating climate change, yet environmental determinants of brain health remain underrecognized within neurology. Climate-related factors—including air pollution, extreme h ... Full text CiteAuthor Response: Genetic Associations With an Amyotrophic Lateral Sclerosis Reversal Phenotype.
Journal Article Neurology · November 11, 2025 Full text Link to item CiteRecent Grants
SEA-NOBI-ALS
Clinical TrialPrincipal Investigator · Awarded by WideTrial, Inc. · 2025 - 2028Pridopine EAP 2 (Clinical Site Agreement)
ResearchPrincipal Investigator · Awarded by Massachusetts General Hospital · 2024 - 2027Duke ALS Clinic & Duke Telemedicine ALS Clinic
Institutional SupportPrincipal Investigator · Awarded by Amyotrophic Lateral Sclerosis Association · 2022 - 2027View All Grants
Education
University of Connecticut ·
1995
M.D.
University of Connecticut ·
1995
Ph.D.