Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Ph.D., State University of New York, Potsdam 2004
• 

  Previous Appointments & Affiliations

  • Associate Professor in Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences, Psychiatry & Behavioral Sciences 2016 - 2020
  • Assistant Professor of Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences, Psychiatry & Behavioral Sciences 2013 - 2016
  • Assistant Professor of Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Clinical Science Departments 2007 - 2013
  • Clinical Associate in the Department of Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Clinical Science Departments 2004 - 2007
• Research
• 

  Selected Grants

  • Exercise and Pharmacotherapy for Anxiety in Cardiac Patients awarded by National Institutes of Health 2015 - 2022
  • Depression and Heart Failure Disease Progression awarded by National Institutes of Health 2014 - 2019
  • Coping Skills Training in Heart Failure: Outcomes and Mechanisms awarded by National Institutes of Health 2009 - 2015
  • Exercise, Depression, and Cardiac Risk awarded by National Institutes of Health 2006 - 2012
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Blumenthal, James A., Patrick J. Smith, Wei Jiang, Alan Hinderliter, Lana L. Watkins, Benson M. Hoffman, William E. Kraus, et al. “Exercise and Escitalopram in the Treatment of Anxiety in Patients with Coronary Heart Disease: One Year Follow-Up of the UNWIND Randomized Clinical Trial.” J Cardiovasc Dev Dis 9, no. 10 (September 22, 2022). https://doi.org/10.3390/jcdd9100320.
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    • Blumenthal, James A., Patrick J. Smith, Wei Jiang, Alan Hinderliter, Lana L. Watkins, Benson M. Hoffman, William E. Kraus, et al. “Longer term benefits of exercise and escitalopram in the treatment of anxiety in patients with coronary heart disease: Six month follow-up of the UNWIND randomized clinical trial.” Am Heart J 251 (September 2022): 91–100. https://doi.org/10.1016/j.ahj.2022.05.014.
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    • Blumenthal, James A., Patrick J. Smith, Wei Jiang, Alan Hinderliter, Lana L. Watkins, Benson M. Hoffman, William E. Kraus, Lawrence Liao, Jonathan Davidson, and Andrew Sherwood. “Effect of Exercise, Escitalopram, or Placebo on Anxiety in Patients With Coronary Heart Disease: The Understanding the Benefits of Exercise and Escitalopram in Anxious Patients With Coronary Heart Disease (UNWIND) Randomized Clinical Trial.” Jama Psychiatry 78, no. 11 (November 1, 2021): 1270–78. https://doi.org/10.1001/jamapsychiatry.2021.2236.
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    • Malian, Hannah M., Patrick J. Smith, Benson Hoffman, Wei Jiang, Katharine Ammerman, William E. Kraus, Alan Hinderliter, Andrew Sherwood, and James A. Blumenthal. “Effects of Acute Exercise on Anxiety Ratings in Patients With Coronary Heart Disease and Elevated Anxiety.” Journal of Cardiopulmonary Rehabilitation and Prevention 41, no. 4 (July 2021): 277–81. https://doi.org/10.1097/hcr.0000000000000579.
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    • Blumenthal, James A., Michael A. Babyak, Wade Edward Craighead, Jonathan Davidson, Alan Hinderliter, Benson Hoffman, Pudugramam Murali Doraiswamy, and Andrew Sherwood. “The role of comorbid anxiety in exercise and depression trials: Secondary analysis of the SMILE-II randomized clinical trial.” Depress Anxiety 38, no. 2 (February 2021): 124–33. https://doi.org/10.1002/da.23088.
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    • Blumenthal, James A., Yidan Zhu, Gary G. Koch, Patrick J. Smith, Lana L. Watkins, Alan L. Hinderliter, Benson M. Hoffman, et al. “The modifying effects of social support on psychological outcomes in patients with heart failure.” Health Psychol 38, no. 6 (June 2019): 502–8. https://doi.org/10.1037/hea0000716.
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    • Smith, Patrick J., James A. Blumenthal, Alan L. Hinderliter, Lana L. Watkins, Benson M. Hoffman, and Andrew Sherwood. “Microvascular Endothelial Function and Neurocognition Among Adults With Major Depressive Disorder.” Am J Geriatr Psychiatry 26, no. 10 (October 2018): 1061–69. https://doi.org/10.1016/j.jagp.2018.06.011.
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    • Smith, Patrick J., Laurie D. Snyder, Scott M. Palmer, Benson M. Hoffman, Gregory L. Stonerock, Krista K. Ingle, Caroline K. Saulino, and James A. Blumenthal. “Depression, social support, and clinical outcomes following lung transplantation: a single-center cohort study.” Transpl Int 31, no. 5 (May 2018): 495–502. https://doi.org/10.1111/tri.13094.
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    • Smith, Patrick J., Gregory L. Stonerock, Krista K. Ingle, Caroline K. Saulino, Benson Hoffman, Brian Wasserman, James A. Blumenthal, et al. “Neurological Sequelae and Clinical Outcomes After Lung Transplantation.” Transplant Direct 4, no. 4 (April 2018): e353. https://doi.org/10.1097/TXD.0000000000000766.
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    • Gerity, Sandra L., Susan G. Silva, John M. Reynolds, Benson Hoffman, and Marilyn H. Oermann. “Multimedia Education Reduces Anxiety in Lung Transplant Patients.” Prog Transplant 28, no. 1 (March 2018): 83–86. https://doi.org/10.1177/1526924817746910.
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    • Smith, P. J., J. A. Blumenthal, B. M. Hoffman, R. D. Davis, and S. M. Palmer. “Postoperative cognitive dysfunction and mortality following lung transplantation.” Am J Transplant 18, no. 3 (March 2018): 696–703. https://doi.org/10.1111/ajt.14570.
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    • Smith, Patrick J., James A. Blumenthal, Laurie D. Snyder, Joseph P. Mathew, Michael T. Durheim, Benson M. Hoffman, Sarah K. Rivelli, and Scott M. Palmer. “Depressive symptoms and early mortality following lung transplantation: A pilot study.” Clin Transplant 31, no. 2 (February 2017). https://doi.org/10.1111/ctr.12874.
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    • Sherwood, Andrew, James A. Blumenthal, Gary G. Koch, Benson M. Hoffman, Lana L. Watkins, Patrick J. Smith, Christopher M. O’Connor, et al. “Effects of Coping Skills Training on Quality of Life, Disease Biomarkers, and Clinical Outcomes in Patients With Heart Failure: A Randomized Clinical Trial.” Circ Heart Fail 10, no. 1 (January 2017). https://doi.org/10.1161/CIRCHEARTFAILURE.116.003410.
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    • Blumenthal, James A., Bryan J. Feger, Patrick J. Smith, Lana L. Watkins, Wei Jiang, Jonathan Davidson, Benson M. Hoffman, et al. “Treatment of anxiety in patients with coronary heart disease: Rationale and design of the UNderstanding the benefits of exercise and escitalopram in anxious patients WIth coroNary heart Disease (UNWIND) randomized clinical trial.” Am Heart J 176 (June 2016): 53–62. https://doi.org/10.1016/j.ahj.2016.03.003.
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    • Sherwood, Andrew, James A. Blumenthal, Patrick J. Smith, Lana L. Watkins, Benson M. Hoffman, and Alan L. Hinderliter. “Effects of Exercise and Sertraline on Measures of Coronary Heart Disease Risk in Patients With Major Depression: Results From the SMILE-II Randomized Clinical Trial.” Psychosom Med 78, no. 5 (June 2016): 602–9. https://doi.org/10.1097/PSY.0000000000000301.
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    • Smith, Patrick J., James A. Blumenthal, Benson M. Hoffman, Sarah K. Rivelli, Scott M. Palmer, Robert D. Davis, and Joseph P. Mathew. “Reduced Cerebral Perfusion Pressure during Lung Transplant Surgery Is Associated with Risk, Duration, and Severity of Postoperative Delirium.” Ann Am Thorac Soc 13, no. 2 (February 2016): 180–87. https://doi.org/10.1513/AnnalsATS.201507-454OC.
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    • Smith, P. J., J. A. Blumenthal, E. P. Trulock, K. E. Freedland, R. M. Carney, R. D. Davis, B. M. Hoffman, and S. M. Palmer. “Psychosocial Predictors of Mortality Following Lung Transplantation.” Am J Transplant 16, no. 1 (January 2016): 271–77. https://doi.org/10.1111/ajt.13447.
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    • Hoffman, Benson M., Gregory L. Stonerock, Patrick J. Smith, C Virginia F. O’Hayer, Scott Palmer, Robert D. Davis, Keiko Kurita, Robert M. Carney, Kenneth Freeland, and James A. Blumenthal. “Development and psychometric properties of the Pulmonary-specific Quality-of-Life Scale in lung transplant patients.” J Heart Lung Transplant 34, no. 8 (August 2015): 1058–65. https://doi.org/10.1016/j.healun.2015.03.005.
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    • Stonerock, Gregory L., Benson M. Hoffman, Patrick J. Smith, and James A. Blumenthal. “Exercise as Treatment for Anxiety: Systematic Review and Analysis.” Ann Behav Med 49, no. 4 (August 2015): 542–56. https://doi.org/10.1007/s12160-014-9685-9.
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    • Smith, Patrick J., James A. Blumenthal, Robert M. Carney, Kenneth E. Freedland, C Virginia F. O’Hayer, Elbert P. Trulock, Tereza Martinu, et al. “Neurobehavioral functioning and survival following lung transplantation.” Chest 145, no. 3 (March 1, 2014): 604–11. https://doi.org/10.1378/chest.12-2127.
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    • Combs, Kory, Patrick J. Smith, Andrew Sherwood, Benson Hoffman, Robert M. Carney, Kenneth Freedland, W Edward Craighead, and James A. Blumenthal. “Impact of sleep complaints and depression outcomes among participants in the standard medical intervention and long-term exercise study of exercise and pharmacotherapy for depression.” J Nerv Ment Dis 202, no. 2 (February 2014): 167–71. https://doi.org/10.1097/NMD.0000000000000085.
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    • Blumenthal, James A., Andrew Sherwood, Michael A. Babyak, Lana L. Watkins, Patrick J. Smith, Benson M. Hoffman, C Virginia F. O’Hayer, et al. “Exercise and pharmacological treatment of depressive symptoms in patients with coronary heart disease: results from the UPBEAT (Understanding the Prognostic Benefits of Exercise and Antidepressant Therapy) study.” J Am Coll Cardiol 60, no. 12 (September 18, 2012): 1053–63. https://doi.org/10.1016/j.jacc.2012.04.040.
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    • Hoffman, B. M., J. A. Blumenthal, R. C. Carney, C. V. F. O’Hayer, K. Freedland, P. J. Smith, M. A. Babyak, et al. “Changes in neurocognitive functioning following lung transplantation.” Am J Transplant 12, no. 9 (September 2012): 2519–25. https://doi.org/10.1111/j.1600-6143.2012.04072.x.
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    • Blumenthal, James A., Patrick J. Smith, and Benson M. Hoffman. “Is Exercise a Viable Treatment for Depression?” Acsms Health Fit J 16, no. 4 (July 2012): 14–21. https://doi.org/10.1249/01.FIT.0000416000.09526.eb.
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    • Goetzinger, Amy M., James A. Blumenthal, C Virginia O’Hayer, Michael A. Babyak, Benson M. Hoffman, Lephuong Ong, R Duane Davis, et al. “Stress and coping in caregivers of patients awaiting solid organ transplantation.” Clin Transplant 26, no. 1 (2012): 97–104. https://doi.org/10.1111/j.1399-0012.2011.01431.x.
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    • Sherwood, Andrew, Christopher M. O’Connor, Faye S. Routledge, Alan L. Hinderliter, Lana L. Watkins, Michael A. Babyak, Gary G. Koch, et al. “Coping effectively with heart failure (COPE-HF): design and rationale of a telephone-based coping skills intervention.” J Card Fail 17, no. 3 (March 2011): 201–7. https://doi.org/10.1016/j.cardfail.2010.11.001.
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    • Wang, Jenny T., Benson Hoffman, and James A. Blumenthal. “Management of depression in patients with coronary heart disease: association, mechanisms, and treatment implications for depressed cardiac patients.” Expert Opin Pharmacother 12, no. 1 (January 2011): 85–98. https://doi.org/10.1517/14656566.2010.513701.
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    • Hoffman, Benson M., Michael A. Babyak, W Edward Craighead, Andrew Sherwood, P Murali Doraiswamy, Michael J. Coons, and James A. Blumenthal. “Exercise and pharmacotherapy in patients with major depression: one-year follow-up of the SMILE study.” Psychosom Med 73, no. 2 (2011): 127–33. https://doi.org/10.1097/PSY.0b013e31820433a5.
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    • Smith, Patrick J., James A. Blumenthal, Michael A. Babyak, Lana L. Watkins, Alan Hinderliter, Benson M. Hoffman, David C. Steffens, Andrew Sherwood, and P Murali Doraiswamy. “Cerebrovascular risk factors and cerebral hyperintensities among middle-aged and older adults with major depression.” Am J Geriatr Psychiatry 18, no. 9 (September 2010): 848–52. https://doi.org/10.1097/JGP.0b013e3181dba0fa.
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    • Hoffman, Benson M., Michael J. Coons, and Paul C. Kuo. “Personality differences between surgery residents, nonsurgery residents, and medical students.” Surgery 148, no. 2 (August 2010): 187–93. https://doi.org/10.1016/j.surg.2010.04.005.
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    • Smith, Patrick J., James A. Blumenthal, Benson M. Hoffman, Harris Cooper, Timothy A. Strauman, Kathleen Welsh-Bohmer, Jeffrey N. Browndyke, and Andrew Sherwood. “Aerobic exercise and neurocognitive performance: a meta-analytic review of randomized controlled trials.” Psychosom Med 72, no. 3 (April 2010): 239–52. https://doi.org/10.1097/PSY.0b013e3181d14633.
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    • Babyak, Michael A., James A. Blumenthal, Alan Hinderliter, Benson Hoffman, Robert A. Waugh, R Edward Coleman, and Andrew Sherwood. “Prognosis after change in left ventricular ejection fraction during mental stress testing in patients with stable coronary artery disease.” Am J Cardiol 105, no. 1 (January 1, 2010): 25–28. https://doi.org/10.1016/j.amjcard.2009.08.647.
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    • Hoffman, B. M., A. Sherwood, P. J. Smith, M. A. Babyak, P. M. Doraiswamy, A. Hinderliter, and J. A. Blumenthal. “Cardiovascular disease risk, vascular health and erectile dysfunction among middle-aged, clinically depressed men.” Int J Impot Res 22, no. 1 (2010): 30–35. https://doi.org/10.1038/ijir.2009.43.
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    • Hoffman, B. M., M. A. Babyak, A. Sherwood, E. E. Hill, S. M. Patidar, P. M. Doraiswamy, and J. A. Blumenthal. “Effects of aerobic exercise on sexual functioning in depressed adults.” Mental Health and Physical Activity 2, no. 1 (June 1, 2009): 23–28. https://doi.org/10.1016/j.mhpa.2008.12.001.
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    • Smith, Patrick J., James A. Blumenthal, Michael A. Babyak, P Murali Doraiswamy, Alan Hinderliter, Benson M. Hoffman, Robert Waugh, and Andrew Sherwood. “Intima-media thickness and age of first depressive episode.” Biol Psychol 80, no. 3 (March 2009): 361–64. https://doi.org/10.1016/j.biopsycho.2008.11.001.
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    • Taylor, Jessica L., Patrick J. Smith, Michael A. Babyak, Krista A. Barbour, Benson M. Hoffman, Deborah L. Sebring, R Duane Davis, et al. “Coping and quality of life in patients awaiting lung transplantation.” J Psychosom Res 65, no. 1 (July 2008): 71–79. https://doi.org/10.1016/j.jpsychores.2008.04.009.
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    • Hoffman, Benson M., James A. Blumenthal, Michael A. Babyak, Patrick J. Smith, Sharon D. Rogers, P Murali Doraiswamy, and Andrew Sherwood. “Exercise fails to improve neurocognition in depressed middle-aged and older adults.” Med Sci Sports Exerc 40, no. 7 (July 2008): 1344–52. https://doi.org/10.1249/MSS.0b013e31816b877c.
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    • Blumenthal, J. A., A. Sherwood, M. A. Babyak, P. M. Doraiswamy, and B. M. Hoffman. “Response to letters to the editor [3].” Psychosomatic Medicine 70, no. 2 (February 1, 2008): 264–65. https://doi.org/10.1097/01.psy.0000311332.34779.56.
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    • Hoffman, Benson M., Rebecca K. Papas, David K. Chatkoff, and Robert D. Kerns. “Meta-analysis of psychological interventions for chronic low back pain.” Health Psychol 26, no. 1 (January 2007): 1–9. https://doi.org/10.1037/0278-6133.26.1.1.
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    • Blumenthal, James A., Andrew Sherwood, Sharon D. Rogers, Michael A. Babyak, P Murali Doraiswamy, Lana Watkins, Benson M. Hoffman, et al. “Understanding prognostic benefits of exercise and antidepressant therapy for persons with depression and heart disease: the UPBEAT study--rationale, design, and methodological issues.” Clin Trials 4, no. 5 (2007): 548–59. https://doi.org/10.1177/1740774507083388.
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    • Blumenthal, James A., Michael A. Babyak, P Murali Doraiswamy, Lana Watkins, Benson M. Hoffman, Krista A. Barbour, Steve Herman, et al. “Exercise and pharmacotherapy in the treatment of major depressive disorder.” Psychosom Med 69, no. 7 (2007): 587–96. https://doi.org/10.1097/PSY.0b013e318148c19a.
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    • Smith, Patrick J., James A. Blumenthal, Michael A. Babyak, Benson M. Hoffman, P Murali Doraiswamy, Robert Waugh, Alan Hinderliter, and Andrew Sherwood. “Cerebrovascular risk factors, vascular disease, and neuropsychological outcomes in adults with major depression.” Psychosom Med 69, no. 6 (2007): 578–86. https://doi.org/10.1097/PSY.0b013e31812f7b8e.
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    • Cooper, Theodore V., Margaret Dundon, Benson M. Hoffman, and Colby J. Stoever. “General and smoking cessation related weight concerns in veterans.” Addict Behav 31, no. 4 (April 2006): 722–25. https://doi.org/10.1016/j.addbeh.2005.05.045.
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    • Hoffman, B. M., M. A. Zevon, M. C. D’Arrigo, and T. B. Cecchini. “Erratum: Screening for distress in cancer patients: The NCCN rapid-screening measure (Psycho-Oncology) (2004) vol. 13 (11) (792-799)).” Psycho Oncology 13, no. 11 (November 1, 2004): 831. https://doi.org/10.1002/pon.875.
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    • Hoffman, Benson M., Michael A. Zevon, Mary C. D’Arrigo, and Tracy B. Cecchini. “Screening for distress in cancer patients: the NCCN rapid-screening measure.” Psychooncology 13, no. 11 (November 2004): 792–99. https://doi.org/10.1002/pon.796.
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    • Hoffman, B. M., and S. T. Meier. “An individualized approach to managed mental health care in colleges and universities: A case study.” Journal of College Student Psychotherapy 15, no. 4 (July 13, 2001): 49–63. https://doi.org/10.1300/J035v15n04_06.
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    • Chesney, M. A., W. S. Agras, H. Benson, J. A. Blumenthal, B. T. Engel, J. P. Foreyt, P. G. Kaufmann, R. M. Levenson, T. G. Pickering, and W. C. Randall. “Nonpharmacologic approaches to the treatment of hypertension.” Circulation 76, no. 1 Pt 2 (July 1987): I104–9.
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  • Book Sections

    • Hoffman, B. M., C. K. Saulino, and P. J. Smith. “Psychosocial aspects of kidney transplantation and living kidney donation.” In Kidney Transplantation - Principles and Practice, 709–23, 2019. https://doi.org/10.1016/B978-0-323-53186-3.00040-1.
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    • Hoffman, B. M., A. Sherwood, J. A. Blumenthal, and A. Hinderliter. “Biobehavioral interventions in heart failure.” In The Handbook of Behavioral Medicine, 621–48, 2014. https://doi.org/10.1002/9781118453940.ch30.
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