Beth Ann Sullivan
Associate Professor of Molecular Genetics and Microbiology
Research in the Sullivan Lab is focused on chromosome organization, with a specific emphasis on the genomics and epigenetics of the chromosomal locus called the centromere and the formation and fate of chromosome abnormalities that are associated with birth defects, reproductive abnormalities, and cancer. The centromere is a specialized chromosomal site involved in chromosome architecture and movement, kinetochore function, heterochromatin assembly, and sister chromatid cohesion. Our experiments have uncovered a unique type of chromatin (CEN chromatin) formed exclusively at the centromere by replacement of core histone H3 by the centromeric histone variant CENP-A. We are currently exploring the composition of CEN chromatin and its relationship to the underlying alpha satellite DNA at the centromere. Recently, we discovered that the amount and type of genomic variation within alpha satellite DNA affects centromere location and chromosome stability. Variation within the repetitive portion of the human genome has not been well studied, primarily because alpha satellite DNA is part of the 10% of the human genome that has been excluded from the contiguous genome assembly. We are currently using endogenous chromosomes and human artificial chromosomes (HACs) to investigate how alpha satellite variation affects centromeric transcription, recruitment of centromere proteins, de novo
centromere assembly, kinetochore architecture, and ultimately, chromosome stability. Finally, the lab studies human chromosomal abnormalities with two centromeres, called dicentric chromosomes. Originally described by Barbara McClintock in the 1930s, dicentrics have been considered inherently unstable chromosomes that trigger genome instability. However, dicentric chromosomes in humans are very stable and often transmitted through the germ line. Using several approaches to experimentally reproduce dicentric chromosome rearrangements in human cells, we are exploring dicentric formation and fate, using genome engineering (CRISPR), live cell imaging, and quantitative microscopy.
Current Appointments & Affiliations
- Associate Professor of Molecular Genetics and Microbiology, Molecular Genetics and Microbiology, Basic Science Departments 2013
- Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 2005
- Associate of the Duke Initiative for Science & Society, Duke Science & Society, Initiatives 2018
Contact Information
- 213 Research Drive, 361 CARL, Durham, NC 27710
- Box 3054 DUMC, 361 CARL, Durham, NC 27710
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beth.sullivan@duke.edu
(919) 684-9038
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Sullivan Lab
- Background
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Education, Training, & Certifications
- Ph.D., University of Maryland - Baltimore 1995
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Duke Appointment History
- Assistant Professor of Molecular Genetics and Microbiology, Molecular Genetics and Microbiology, Basic Science Departments 2006 - 2013
- Visiting Assistant Professor of Molecular Genetics and Microbiology, Molecular Genetics and Microbiology, Basic Science Departments 2005 - 2006
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Leadership & Clinical Positions at Duke
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Director, Genetics and Genomics Cluster, Duke Focus Program 2015-
Co-Director, University Program in Genetics and Genomics 2010-2014
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Director, Genetics and Genomics Cluster, Duke Focus Program 2015-
- Recognition
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In the News
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AUG 30, 2016 -
NOV 24, 2015
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Awards & Honors
- Expertise
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Subject Headings
- Aneuploidy
- Cell Cycle
- Centromere
- Centromere Protein B
- Chromatids
- Chromatin
- Chromatin Immunoprecipitation
- Chromosomal Instability
- Chromosomal Proteins, Non-Histone
- Chromosome Aberrations
- Chromosome Deletion
- Chromosome Disorders
- Chromosome Segregation
- Chromosomes
- Chromosomes, Human
- DNA
- DNA Damage
- DNA Methylation
- DNA Repair
- DNA Replication
- DNA, Ribosomal
- DNA, Satellite
- DNA-Binding Proteins
- Epigenesis, Genetic
- Epigenomics
- Eukaryota
- Fluorescent Antibody Technique
- Gene Expression Regulation
- Gene Silencing
- Genome
- Heterochromatin
- Histone Code
- Histones
- Immunofluorescence
- Microscopy, Fluorescence
- Mitosis
- Molecular Probe Techniques
- Polymorphism, Genetic
- Telomere
- Transcription
- Translocation, Genetic
- Research
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Selected Grants
- Summer Scholars Program in Genome Sciences and Medicine awarded by National Institutes of Health 2017 - 2022
- Genomic Analysis of Centromere Assembly and Function awarded by National Institutes of Health 2017 - 2021
- Dicentric chromosome formation and stability in humans awarded by National Institutes of Health 2012 - 2017
- Genomic and Epigenetic Mechanisms of Human Centromere Assembly and Chromosome Stability awarded by March of Dimes 2013 - 2016
- Mechanisms of Centromere Function awarded by National Institutes of Health 2010 - 2013
- Mechanisms of Human Chromosome Rearrangement and Stability awarded by March of Dimes 2010 - 2013
- Organization and Regulation of Eukaryotic Centromeres awarded by National Institutes of Health 2005 - 2010
- Epigenetic Determinants of Centromere Function and Stability in Human Dicentric Chromosomes awarded by March of Dimes 2006 - 2009
- Organization and Stability of Centromeric Chromatin awarded by March of Dimes Birth Defects Foundation 2005 - 2006
- Publications & Artistic Works
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Selected Publications
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Academic Articles
- McNulty, SM, & Sullivan, BA. (2019, January). Going the distance: Neocentromeres make long-range contacts with heterochromatin. The Journal of Cell Biology , 218 (1), 5-7. Full Text
- McNulty, SM, & Sullivan, BA. (2018, September). Alpha satellite DNA biology: finding function in the recesses of the genome. Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology , 26 (3), 115-138. (Review) Full Text
- Larsen, PA, Harris, RA, Liu, Y, Murali, SC, Campbell, CR, Brown, AD, Sullivan, BA, Shelton, J, Brown, SJ, Raveendran, M, Dudchenko, O, Machol, I, Durand, NC, Shamim, MS, Aiden, EL, Muzny, DM, Gibbs, RA, Yoder, AD, Rogers, J, & Worley, KC. (2017, November 16). Hybrid de novo genome assembly and centromere characterization of the gray mouse lemur (Microcebus murinus). Bmc Biology , 15 (1), 110-null. Full Text
- Iwata-Otsubo, A, Dawicki-McKenna, JM, Akera, T, Falk, SJ, Chmátal, L, Yang, K, Sullivan, BA, Schultz, RM, Lampson, MA, & Black, BE. (2017, August). Expanded Satellite Repeats Amplify a Discrete CENP-A Nucleosome Assembly Site on Chromosomes that Drive in Female Meiosis. Current Biology : Cb , 27 (15), 2365-2373.e8. Full Text
- Johnson, WL, Yewdell, WT, Bell, JC, McNulty, SM, Duda, Z, O'Neill, RJ, Sullivan, BA, & Straight, AF. (2017, August 1). RNA-dependent stabilization of SUV39H1 at constitutive heterochromatin.(Published online) Elife , 6 . Full Text Open Access Copy Link to Item
- Johnson, WL, Yewdell, WT, Bell, JC, McNulty, SM, Duda, Z, O’Neill, RJ, Sullivan, BA, & Straight, AF. (2017, August 1). RNA-dependent stabilization of SUV39H1 at constitutive heterochromatin. Elife , 6 . Full Text
- McNulty, SM, Sullivan, LL, & Sullivan, BA. (2017, August). Human Centromeres Produce Chromosome-Specific and Array-Specific Alpha Satellite Transcripts that Are Complexed with CENP-A and CENP-C. Developmental Cell , 42 (3), 226-240.e6. Full Text
- Sullivan, LL, Chew, K, & Sullivan, BA. (2017, July). α satellite DNA variation and function of the human centromere. Nucleus (Austin, Tex.) , 8 (4), 331-339. Full Text
- McNulty, SM, & Sullivan, BA. (2017). Centromere Silencing Mechanisms. Prog Mol Subcell Biol , 56 , 233-255. Full Text Link to Item
- Sullivan, LL, Maloney, KA, Towers, AJ, Gregory, SG, & Sullivan, BA. (2016, December). Human centromere repositioning within euchromatin after partial chromosome deletion. Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology , 24 (4), 451-466. Full Text
- Aldrup-MacDonald, ME, Kuo, ME, Sullivan, LL, Chew, K, & Sullivan, BA. (2016, October). Genomic variation within alpha satellite DNA influences centromere location on human chromosomes with metastable epialleles. Genome Research , 26 (10), 1301-1311. Full Text Open Access Copy
- Ross, JE, Woodlief, KS, & Sullivan, BA. (2016, January). Inheritance of the CENP-A chromatin domain is spatially and temporally constrained at human centromeres. Epigenetics & Chromatin , 9 , 20-null. Full Text Open Access Copy
- Scott, KC, & Sullivan, BA. (2014, February). Neocentromeres: a place for everything and everything in its place. Trends in Genetics : Tig , 30 (2), 66-74. (Review) Full Text
- Aldrup-Macdonald, ME, & Sullivan, BA. (2014, January). The past, present, and future of human centromere genomics. Genes , 5 (1), 33-50. Full Text Open Access Copy
- Stimpson, KM, Sullivan, LL, Kuo, ME, & Sullivan, BA. (2014, January). Nucleolar organization, ribosomal DNA array stability, and acrocentric chromosome integrity are linked to telomere function. PLoS ONE , 9 (3), e92432-. Full Text Open Access Copy
- Earnshaw, WC, Allshire, RC, Black, BE, Bloom, K, Brinkley, BR, Brown, W, Cheeseman, IM, Choo, KHA, Copenhaver, GP, Deluca, JG, Desai, A, Diekmann, S, Erhardt, S, Fitzgerald-Hayes, M, Foltz, D, Fukagawa, T, Gassmann, R, Gerlich, DW, Glover, DM, Gorbsky, GJ, Harrison, SC, Heun, P, Hirota, T, Jansen, LET, Karpen, G, Kops, GJPL, Lampson, MA, Lens, SM, Losada, A, Luger, K, Maiato, H, Maddox, PS, Margolis, RL, Masumoto, H, McAinsh, AD, Mellone, BG, Meraldi, P, Musacchio, A, Oegema, K, O'Neill, RJ, Salmon, ED, Scott, KC, Straight, AF, Stukenberg, PT, Sullivan, BA, Sullivan, KF, Sunkel, CE, Swedlow, JR, Walczak, CE, Warburton, PE, Westermann, S, Willard, HF, Wordeman, L, Yanagida, M, Yen, TJ, Yoda, K, & Cleveland, DW. (2013, April 12). Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant. Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology , 21 (2), 101-106. Full Text
- Maloney, KA, Sullivan, LL, Matheny, JE, Strome, ED, Merrett, SL, Ferris, A, & Sullivan, BA. (2012, August). Functional epialleles at an endogenous human centromere. Proceedings of the National Academy of Sciences of the United States of America , 109 (34), 13704-13709. Full Text Open Access Copy
- Stimpson, KM, Matheny, JE, & Sullivan, BA. (2012, July). Dicentric chromosomes: unique models to study centromere function and inactivation. Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology , 20 (5), 595-605. (Review) Full Text
- Stimpson, KM, & Sullivan, BA. (2012, January 17). Centromeres poised en pointe: CDKs put a hold on CENP-A assembly. Dev Cell , 22 (1), 1-2. Full Text Link to Item
- O'Neill, RJ, & Sullivan, BA. (2012). Foreword: The centromere and kinetochore in creatures great and small. Chromosome Research , 20 (5), 461-463. Full Text
- Sullivan, LL, Boivin, CD, Mravinac, B, Song, IY, & Sullivan, BA. (2011, May). Genomic size of CENP-A domain is proportional to total alpha satellite array size at human centromeres and expands in cancer cells. Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology , 19 (4), 457-470. Full Text Open Access Copy
- Stimpson, KM, & Sullivan, BA. (2011, January 19). Histone H3K4 methylation keeps centromeres open for business. EMBO J , 30 (2), 233-234. Full Text Link to Item
- Stimpson, KM, & Sullivan, BA. (2010, December). Epigenomics of centromere assembly and function. Current Opinion in Cell Biology , 22 (6), 772-780. (Review) Full Text
- Stimpson, KM, Song, IY, Jauch, A, Holtgreve-Grez, H, Hayden, KE, Bridger, JM, & Sullivan, BA. (2010, August 12). Telomere disruption results in non-random formation of de novo dicentric chromosomes involving acrocentric human chromosomes. Plos Genetics , 6 (8). Full Text Open Access Copy
- Sullivan, BA. (2010). Optical mapping of protein-DNA complexes on chromatin fibers. Methods Mol Biol , 659 , 99-115. Full Text Link to Item
- Sullivan, BA. (2009, December 1). The centromere. , 45-76. (Chapter) Full Text
- Balakumaran, BS, Porrello, A, Hsu, DS, Glover, W, Foye, A, Leung, JY, Sullivan, BA, Hahn, WC, Loda, M, & Febbo, PG. (2009, October). MYC activity mitigates response to rapamycin in prostate cancer through eukaryotic initiation factor 4E-binding protein 1-mediated inhibition of autophagy. Cancer Research , 69 (19), 7803-7810. Full Text Open Access Copy
- Gopalakrishnan, S, Sullivan, BA, Trazzi, S, Della Valle, G, & Robertson, KD. (2009, September). DNMT3B interacts with constitutive centromere protein CENP-C to modulate DNA methylation and the histone code at centromeric regions. Human Molecular Genetics , 18 (17), 3178-3193. Full Text
- Mravinac, B, Sullivan, LL, Reeves, JW, Yan, CM, Kopf, KS, Farr, CJ, Schueler, MG, & Sullivan, BA. (2009, August 12). Histone modifications within the human X centromere region. Plos One , 4 (8), e6602-null. Full Text Open Access Copy
- Stimpson, KM, Jauch, A, & Sullivan, BA. (2009, May). Non-random chromosome fusions occur after transient telomere destabilization. CHROMOSOME RESEARCH , 17 (4), 557-557. Link to Item
- Gao, F, Ponte, JF, Levy, M, Papageorgis, P, Cook, NM, Ozturk, S, Lambert, AW, Thiagalingam, A, Abdolmaleky, HM, Sullivan, BA, & Thiagalingam, S. (2009, April 1). hBub1 negatively regulates p53 mediated early cell death upon mitotic checkpoint activation. Cancer Biology and Therapy , 8 (7). Full Text
- Gao, F, Ponte, JF, Levy, M, Papageorgis, P, Cook, NM, Ozturk, S, Lambert, AW, Thiagalingam, A, Abdolmaleky, HM, Sullivan, BA, & Thiagalingam, S. (2009, April). hBub1 negatively regulates p53 mediated early cell death upon mitotic checkpoint activation. Cancer Biol Ther , 8 (7), 548-556. Link to Item
- Kim, J-H, Ebersole, T, Kouprina, N, Noskov, VN, Ohzeki, J-I, Masumoto, H, Mravinac, B, Sullivan, BA, Pavlicek, A, Dovat, S, Pack, SD, Kwon, Y-W, Flanagan, PT, Loukinov, D, Lobanenkov, V, & Larionov, V. (2009, April). Human gamma-satellite DNA maintains open chromatin structure and protects a transgene from epigenetic silencing. Genome Research , 19 (4), 533-544. Full Text
- Dai, J, Sullivan, BA, & Higgins, JMG. (2006, November). Regulation of mitotic chromosome cohesion by Haspin and Aurora B. Developmental Cell , 11 (5), 741-750. Full Text
- (2006, April 18). Correction for Lam et al., Human centromeric chromatin is a dynamic chromosomal domain that can spread over noncentromeric DNA. Proceedings of the National Academy of Sciences , 103 (16), 6410-6410. Full Text
- Lam, AL, Boivin, CD, Bonney, CF, Rudd, MK, & Sullivan, BA. (2006, March 6). Human centromeric chromatin is a dynamic chromosomal domain that can spread over noncentromeric DNA. Proceedings of the National Academy of Sciences of the United States of America , 103 (11), 4186-4191. Full Text
- Schueler, MG, & Sullivan, BA. (2006, January). Structural and functional dynamics of human centromeric chromatin. Annual Review of Genomics and Human Genetics , 7 , 301-313. (Review) Full Text
- Lam, AL, Pazin, DE, & Sullivan, BA. (2005, September). Control of gene expression and assembly of chromosomal subdomains by chromatin regulators with antagonistic functions. Chromosoma , 114 (4), 242-251. (Review) Full Text
- Wilson, KC, Cattel, DJ, Wan, Z, Rahangdale, S, Ren, F, Kornfeld, H, Sullivan, BA, Cruikshank, WW, & Center, DM. (2005, September). Regulation of nuclear Prointerleukin-16 and p27(Kip1) in primary human T lymphocytes. Cellular Immunology , 237 (1), 17-27. Full Text
- Sullivan, BA, & Karpen, GH. (2004, November). Centromeric chromatin exhibits a histone modification pattern that is distinct from both euchromatin and heterochromatin. Nature Structural & Molecular Biology , 11 (11), 1076-1083. Full Text
- Blower, MD, Sullivan, BA, & Karpen, GH. (2002, March). Conserved organization of centromeric chromatin in flies and humans. Developmental Cell , 2 (3), 319-330. Full Text
- Sullivan, BA. (2002, March). Centromere round-up at the heterochromatin corral. Trends Biotechnol , 20 (3), 89-92. Link to Item
- Hoskins, RA, Smith, CD, Carlson, JW, Carvalho, AB, Halpern, A, Kaminker, JS, Kennedy, C, Mungall, CJ, Sullivan, BA, Sutton, GG, Yasuhara, JC, Wakimoto, BT, Myers, EW, Celniker, SE, Rubin, GM, & Karpen, GH. (2002, January). Heterochromatic sequences in a Drosophila whole-genome shotgun assembly. Genome Biology , 3 (12), RESEARCH0085-null. Full Text
- Gong, Y, Slee, RB, Fukai, N, Rawadi, G, Roman-Roman, S, Reginato, AM, Wang, H, Cundy, T, Glorieux, FH, Lev, D, Zacharin, M, Oexle, K, Marcelino, J, Suwairi, W, Heeger, S, Sabatakos, G, Apte, S, Adkins, WN, Allgrove, J, Arslan-Kirchner, M, Batch, JA, Beighton, P, Black, GC, Boles, RG, Boon, LM, Borrone, C, Brunner, HG, Carle, GF, Dallapiccola, B, De Paepe, A, Floege, B, Halfhide, ML, Hall, B, Hennekam, RC, Hirose, T, Jans, A, Jüppner, H, Kim, CA, Keppler-Noreuil, K, Kohlschuetter, A, LaCombe, D, Lambert, M, Lemyre, E, Letteboer, T, Peltonen, L, Ramesar, RS, Romanengo, M, Somer, H, Steichen-Gersdorf, E, Steinmann, B, Sullivan, B, Superti-Furga, A, Swoboda, W, van den Boogaard, MJ, Van Hul, W, Vikkula, M, Votruba, M, Zabel, B, Garcia, T, Baron, R, Olsen, BR, Warman, ML, & Osteoporosis-Pseudoglioma Syndrome Collaborative Group, . (2001, November). LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development. Cell , 107 (4), 513-523. Full Text
- Sullivan, B, & Karpen, G. (2001, August 20). Centromere identity in Drosophila is not determined in vivo by replication timing. J Cell Biol , 154 (4), 683-690. Full Text Link to Item
- Sullivan, BA, Blower, MD, & Karpen, GH. (2001, August). Determining centromere identity: cyclical stories and forking paths. Nat Rev Genet , 2 (8), 584-596. (Review) Full Text Link to Item
- Sullivan, BA, & Bickmore, WA. (2000, June). Unusual chromosome architecture and behaviour at an HSR. Chromosoma , 109 (3), 181-189. Link to Item
- Sullivan, BA, & Willard, HF. (1998, November). Stable dicentric X chromosomes with two functional centromeres. Nature Genetics , 20 (3), 227-228. (Letter) Full Text
- Flejter, WL, Issa, B, Sullivan, BA, Carey, JC, & Brothman, AR. (1998, January 6). Variegated aneuploidy in two siblings: Phenotype, genotype, CENP-E analysis, and literature review. American Journal of Medical Genetics , 75 (1), 45-51. Full Text
- Flejter, WL, Issa, B, Sullivan, BA, Carey, JC, & Brothman, AR. (1998, January 6). Variegated aneuploidy in two siblings: phenotype, genotype, CENP-E analysis, and literature review. Am J Med Genet , 75 (1), 45-51. (Review) Link to Item
- Warburton, PE, Cooke, CA, Bourassa, S, Vafa, O, Sullivan, BA, Stetten, G, Gimelli, G, Warburton, D, Tyler-Smith, C, Sullivan, KF, Poirier, GG, & Earnshaw, WC. (1997, November). Immunolocalization of CENP-A suggests a distinct nucleosome structure at the inner kinetochore plate of active centromeres. Current Biology : Cb , 7 (11), 901-904. Full Text
- Depinet, TW, Zackowski, JL, Earnshaw, WC, Kaffe, S, Sekhon, GS, Stallard, R, Sullivan, BA, Vance, GH, Van Dyke, DL, Willard, HF, Zinn, AB, & Schwartz, S. (1997, August). Characterization of neo-centromeres in marker chromosomes lacking detectable alpha-satellite DNA. Human Molecular Genetics , 6 (8), 1195-1204. Full Text
- Sullivan, BA, Schwartz, S, & Willard, HF. (1996, November 23). Centromeres of the human chromosomes. Environmental and Molecular Mutagenesis , 28 (3), 182-191. Full Text
- Sullivan, BA, Jenkins, LS, Karson, EM, Leana-Cox, J, & Schwartz, S. (1996, July). Evidence for structural heterogeneity from molecular cytogenetic analysis of dicentric Robertsonian translocations. Am J Hum Genet , 59 (1), 167-175. Link to Item
- Sullivan, BA, Schwartz, S, & Willard, HF. (1996, January). Centromeres of human chromosomes. Environmental and Molecular Mutagenesis , 28 (3), 182-191. (Review) Full Text
- Sullivan, BA, & Schwartz, S. (1995, December). Identification of centromeric antigens in dicentric Robertsonian translocations: CENP-C and CENP-E are necessary components of functional centromeres. Human Molecular Genetics , 4 (12), 2189-2197. Full Text
- Sullivan, BA, Schiffer, CA, Patil, SR, Hulseberg, D, Leana-Cox, J, & Schwartz, S. (1995, July 15). Application of FISH to complex chromosomal rearrangements associated with chronic myelogenous leukemia. Cancer Genet Cytogenet , 82 (2), 93-99. Link to Item
- Sullivan, BA, Wolff, DJ, & Schwartz, S. (1994, December). Analysis of centromeric activity in Robertsonian translocations: implications for a functional acrocentric hierarchy. Chromosoma , 103 (7), 459-467. Full Text
- Sullivan, BA, Leana-Cox, J, & Schwartz, S. (1993, August 15). Clarification of subtle reciprocal rearrangements using fluorescence in situ hybridization. Am J Med Genet , 47 (2), 223-230. Full Text Link to Item
- Leana-Cox, J, Levin, S, Surana, R, Wulfsberg, E, Keene, CL, Raffel, LJ, Sullivan, B, & Schwartz, S. (1993, June). Characterization of de novo duplications in eight patients by using fluorescence in situ hybridization with chromosome-specific DNA libraries. Am J Hum Genet , 52 (6), 1067-1073. Link to Item
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Book Sections
- Stimpson, KM, & Sullivan, BA. (2013, February 27). Centromere. In Brenner's Encyclopedia of Genetics: Second Edition (pp. 500-502). Full Text
- Sullivan, BA. (2013, February 27). Nondisjunction. In Brenner's Encyclopedia of Genetics: Second Edition (pp. 90-93). Full Text
- Sullivan, BA. (2013, February 15). Centromeres. In Encyclopedia of Biological Chemistry: Second Edition (pp. 446-450). Full Text
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Conference Papers
- McNulty, SM, Sullivan, LL, & Sullivan, BA. (2017). Human centromeres produce non-coding alpha satellite RNAs that are chromosome-specific and required for centromere protein loading. Link to Item
- McNulty, SM, Sullivan, LL, & Sullivan, BA. (2017). Human centromeres produce non-coding alpha satellite RNAs that are chromosome-specific and required for centromere protein loading. Link to Item
- Sullivan, BA. (2014). Using Chromosome Engineering to Study Centromere Identity and Chromosome Function. Link to Item
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- Teaching & Mentoring
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Recent Courses
- FOCUS 195FS: Special Topics in Focus 2019
- MGM 222FS: Genetics and Epigenetics: The Codes that Control Our Genomes 2019
- MGM 293: Research Independent Study I 2019
- MGM 593: Research Independent Study 2019
- SCISOC 293: Research Independent Study in Genome Sciences 2019
- GENOME 222FS: Genetics and Epigenetics: The Codes that Control Our Genomes 2018
- HOUSECS 59: House Course 2018
- Scholarly, Clinical, & Service Activities
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Service to the Profession
- Member, Program Committee. Annual National Meeting. American Society of Human Genetics. 2018 2018
- Chair. Centromere Biology Meeting. Gordon Research Conferences. 2016 - 2016 2016
- Chair. Awards Committee. American Society of Human Genetics. 2014 - 2015 2014 - 2015
- Vice-Chair. Centromere Biology Meeting. Gordon Research Conferences. 2014 - 2014 2014
- Executive Editor. Chromosome Research. 2013 2013
- Associate Editor. PLOS Genetics. 2012 2012
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Service to Duke
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