Scholars@Duke
Huiwen Bill Xie

Huiwen Bill Xie

Assistant Professor of Pathology
Pathology
bill.xie@duke.edu
3400 Wake Forest Rd., Raleigh, NC 27609
3400 Wake Forest Rd, Raleigh, NC 27609
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Selected Publications

Keratosis reduces sensitivity of anal cytology in detecting anal intraepithelial neoplasia.

Journal Article Gynecol Oncol · February 2012 OBJECTIVE: To identify factors that may contribute to poor sensitivity of anal cytology in contrast to the sensitivity of anoscopy in heterosexual women. METHODS: We analyzed 324 patients with biopsy confirmed diagnosis of genital intraepithelial neoplasia ... Full text Open Access Link to item Cite

Pancreatic FNA in 1000 cases: a comparison of imaging modalities.

Journal Article Gastrointest Endosc · June 2005 BACKGROUND: Image-guided FNA is a popular method for evaluating pancreatic lesions, but few large studies on pancreatic FNA exist. METHODS: Cytologic material, imaging reports, and clinical follow-up information were reviewed from pancreatic FNA cases perf ... Full text Link to item Cite

Clear cell hidradenoma: a mimic of metastatic clear cell tumors.

Journal Article Arch Pathol Lab Med · May 2005 Clear cell hidradenoma is a benign skin appendage tumor that may mimic conventional-type renal cell carcinoma. Histologically, clear cell hidradenoma contains small ductular lumens, focal apocrine and squamoid change, and a less prominent vascular pattern ... Full text Link to item Cite

Significance of histological response to preoperative chemoradiotherapy for pancreatic cancer.

Journal Article Ann Surg Oncol · March 2005 BACKGROUND: Neoadjuvant (preoperative) chemoradiotherapy (CRT) for pancreatic cancer offers theoretical advantages over the standard approach of surgery followed by adjuvant CRT. We hypothesized that histological responses to CRT would be significant progn ... Full text Link to item Cite

The significance of the diagnosis of atypia in breast fine-needle aspiration.

Journal Article Diagn Cytopathol · November 2004 The diagnosis of atypia in breast fine-needle aspiration (FNA) continues to be an area of debate in cytology practice. The aim of this study was to assess the clinical significance of this term and to evaluate potential morphological criteria, which would ... Full text Link to item Cite

Metastases in the pancreas from nonhematologic neoplasms: report of 20 cases evaluated by fine-needle aspiration.

Journal Article Diagn Cytopathol · October 2004 We reviewed fine-needle aspiration (FNA) samples of metastatic tumor in the pancreas from nonhematologic neoplasms over a 5-year period. In 1,050 total procedures, 20 metastases were diagnosed: 9 renal-cell carcinomas (RCCs), 3 melanomas, 2 pulmonary small ... Full text Link to item Cite

How stereotactic core-needle biopsy affected breast fine-needle aspiration utilization: an 11-year institutional review.

Journal Article Diagn Cytopathol · August 2004 To determine the effect of stereotactic core-needle biopsy (SCNB) on the utilization of breast fine-needle aspirate (FNA) biopsy, we retrospectively reviewed 1,568 cases of breast FNAs that were obtained from 1,188 patients between the years 1990 and 2000. ... Full text Link to item Cite

A wolf in sheep's clothing: a non-functioning islet cell tumor of the pancreas masquerading as a microcystic (serous cystic) adenoma.

Journal Article JOP · July 2004 CONTEXT: The endosonographic appearance of a microcystic "honeycomb" lesion of the pancreas usually indicates a serous cystic adenoma. CASE REPORT: We report a case of a non-functioning islet cell tumor that has the typical microcystic "honeycomb" appearan ... Link to item Cite

Primary pancreatic lymphoma evaluated by fine-needle aspiration: findings in 14 cases.

Journal Article Am J Clin Pathol · June 2004 Fine-needle aspiration (FNA) is a popular method for evaluating pancreatic lesions. There is considerable literature on FNA evaluation of primary pancreatic carcinomas, but few studies address the FNA diagnosis of primary pancreatic lymphoma. We reviewed 1 ... Full text Link to item Cite

Giant cell tumor of rib masquerading as thymoma: a diagnostic pitfall in needle core biopsy of the mediastinum.

Journal Article Arch Pathol Lab Med · April 2004 Giant cell tumor of bone is rarely seen in the rib, where it may present as a mediastinal mass. The diagnosis of giant cell tumor of bone is generally straightforward by fine-needle aspiration or needle core biopsy, but sampling problems may lead to confus ... Full text Link to item Cite

IL-4 induces differentiation and expansion of Th2 cytokine-producing eosinophils.

Journal Article J Immunol · February 15, 2004 Innate effector cells that produce Th2-type cytokines are critical in Th2 cell-mediated immune responses. However, it is not known how these cells acquire the ability to produce Th2 cytokines. IL-4 is a potent inducer that directs differentiation of naive ... Full text Link to item Cite

Bronchoscopy-guided transtracheal and transbronchial fine-needle aspiration biopsy: a 5-year institutional review of 111 cases.

Journal Article Diagn Cytopathol · November 2002 We reviewed 111 bronchoscopy-guided transtracheal and transbronchial fine-needle aspiration (TT/TBNA) specimens from 97 patients to determine the sensitivity and specificity for diagnosing neoplasia compared to surgical biopsy and clinical follow-up and to ... Full text Link to item Cite

Integrin functions play a key role in the differentiation of thymocytes in vivo.

Journal Article J Immunol · October 1, 2001 T cells express a variety of surface proteins as they develop to maturity in the thymus. In addition to the TCR-CD3 complex and the two major coreceptors, CD4 and CD8, other surface proteins expressed include receptors for cytokines, growth factors, counte ... Full text Link to item Cite