Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Board Certification, American Board of Internal Medicine 2021
  • Fellowship, Rheumatology, Duke University 2017 - 2020
  • Residency, Internal Medicine, Duke University 2014 - 2017
  • M.D., University of Illinois College of Medicine 2014
• 

  Duke Appointment History

  • Assistant Professor of Medicine, Medicine, Rheumatology and Immunology, Medicine 2020
• Expertise
• 

  Subject Headings

  • Arthritis
  • Exercise
  • Exercise Therapy
  • Muscle Cells
  • Rheumatoid arthritis
• Research
• 

  Selected Grants

  • Accelerated Metabolic Aging in Rheumatoid Arthritis Immune cells and Skeletal Muscle: A Pilot Study awarded by National Institutes of Health 2020 - 2022
  • Weight loss and exercise to improve rheumatoid arthritis cardiovascular risk awarded by National Institutes of Health 2020 - 2022
• Publications & Artistic Works
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  Selected Publications

  • Academic Articles

    • Andonian, Brian J., Andrew Johannemann, Monica J. Hubal, David M. Pober, Alec Koss, William E. Kraus, David B. Bartlett, and Kim M. Huffman. “Altered skeletal muscle metabolic pathways, age, systemic inflammation, and low cardiorespiratory fitness associate with improvements in disease activity following high-intensity interval training in persons with rheumatoid arthritis.” Arthritis Res Ther 23, no. 1 (July 10, 2021): 187. https://doi.org/10.1186/s13075-021-02570-3.
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    • Masi, Alfonse T., Brian Andonian, and Désirée van der Heijde. “Biomechanical Factors May Be the Main Contributor to Entheseal Changes in Normal Adults.” J Rheumatol 48, no. 4 (April 2021): 618–19. https://doi.org/10.3899/jrheum.201296.
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    • Huffman, Kim M., Brian J. Andonian, Dennis M. Abraham, Akshay Bareja, David E. Lee, Lauren H. Katz, Janet L. Huebner, William E. Kraus, and James P. White. “Exercise protects against cardiac and skeletal muscle dysfunction in a mouse model of inflammatory arthritis.” J Appl Physiol (1985) 130, no. 3 (March 1, 2021): 853–64. https://doi.org/10.1152/japplphysiol.00576.2020.
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    • Andonian, Brian J., and Kim M. Huffman. “Skeletal muscle disease in rheumatoid arthritis: the center of cardiometabolic comorbidities?” Curr Opin Rheumatol 32, no. 3 (May 2020): 297–306. https://doi.org/10.1097/BOR.0000000000000697.
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    • Katz, Patricia, Brian J. Andonian, and Kim M. Huffman. “Benefits and promotion of physical activity in rheumatoid arthritis.” Curr Opin Rheumatol 32, no. 3 (May 2020): 307–14. https://doi.org/10.1097/BOR.0000000000000696.
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    • Kelly, Jacob P., Brian J. Andonian, Mahesh J. Patel, Zhen Huang, Linda K. Shaw, Robert W. McGarrah, Salvador Borges-Neto, Eric J. Velazquez, and William E. Kraus. “Trends in cardiorespiratory fitness: The evolution of exercise treadmill testing at a single Academic Medical Center from 1970 to 2012.” Am Heart J 210 (April 2019): 88–97. https://doi.org/10.1016/j.ahj.2019.01.001.
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    • Andonian, Brian J., Ching-Heng Chou, Olga R. Ilkayeva, Timothy R. Koves, Margery A. Connelly, William E. Kraus, Virginia B. Kraus, and Kim M. Huffman. “Plasma MicroRNAs in Established Rheumatoid Arthritis Relate to Adiposity and Altered Plasma and Skeletal Muscle Cytokine and Metabolic Profiles.” Front Immunol 10 (2019): 1475. https://doi.org/10.3389/fimmu.2019.01475.
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    • Andonian, Brian J., David B. Bartlett, Janet L. Huebner, Leslie Willis, Andrew Hoselton, Virginia B. Kraus, William E. Kraus, and Kim M. Huffman. “Effect of high-intensity interval training on muscle remodeling in rheumatoid arthritis compared to prediabetes.” Arthritis Res Ther 20, no. 1 (December 27, 2018): 283. https://doi.org/10.1186/s13075-018-1786-6.
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    • Huffman, Kim M., Ryan Jessee, Brian Andonian, Brittany N. Davis, Rachel Narowski, Janet L. Huebner, Virginia B. Kraus, et al. “Molecular alterations in skeletal muscle in rheumatoid arthritis are related to disease activity, physical inactivity, and disability.” Arthritis Res Ther 19, no. 1 (January 23, 2017): 12. https://doi.org/10.1186/s13075-016-1215-7.
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    • Choe, Jennifer H., Brian J. Andonian, Grace J. Kim, and April Ks Salama. “Autoimmune meningoencephalitis in a melanoma patient treated with ipilimumab.” Immunotherapy 8, no. 10 (October 2016): 1163–67. https://doi.org/10.2217/imt-2016-0058.
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    • Nair, Kalyani, Alfonse T. Masi, Brian J. Andonian, Alexander J. Barry, Brandon A. Coates, John Dougherty, Emily Schaefer, Jacqueline Henderson, and Joseph Kelly. “Stiffness of resting lumbar myofascia in healthy young subjects quantified using a handheld myotonometer and concurrently with surface electromyography monitoring.” J Bodyw Mov Ther 20, no. 2 (April 2016): 388–96. https://doi.org/10.1016/j.jbmt.2015.12.005.
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    • Andonian, Brian J., Alfonse T. Masi, Jean C. Aldag, Alexander J. Barry, Brandon A. Coates, Katherine Emrich, Jacqueline Henderson, Joseph Kelly, and Kalyani Nair. “Greater Resting Lumbar Extensor Myofascial Stiffness in Younger Ankylosing Spondylitis Patients Than Age-Comparable Healthy Volunteers Quantified by Myotonometry.” Arch Phys Med Rehabil 96, no. 11 (November 2015): 2041–47. https://doi.org/10.1016/j.apmr.2015.07.014.
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    • Andonian, Brian J., Kristina M. Prus, and Alfonse T. Masi. “Mechanobiology likely contributes to immunobiology pathways in the pathogenesis of ankylosing spondyltitis.” Clin Exp Rheumatol 30, no. 2 (March 2012): 309–10.
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    • Masi, Alfonse T., Kalyani Nair, Brian J. Andonian, Kristina M. Prus, Joseph Kelly, Jose R. Sanchez, and Jacqueline Henderson. “Integrative structural biomechanical concepts of ankylosing spondylitis.” Arthritis 2011 (2011): 205904. https://doi.org/10.1155/2011/205904.
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    • Andonian, Brian J., Andrew Johannemann, Monica J. Hubal, David M. Pober, Alec Koss, William E. Kraus, David B. Bartlett, and Kim M. Huffman. “Altered Skeletal Muscle Metabolic Pathways, Age, Systemic Inflammation, and Low Cardiorespiratory Fitness Associate with Improvements in Disease Activity Following High-Intensity Interval Training in Persons with Rheumatoid Arthritis,” n.d. https://doi.org/10.21203/rs.3.rs-322342/v1.
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  • Conference Papers

    • Andonian, Brian, David Bartlett, Alec Koss, Deborah Muoio, Timothy Koves, Eugene St Clair, Elizabeth Hauser, William Kraus, and Kim Huffman. “High-Intensity Interval Training Increases Rheumatoid Arthritis Cardiorespiratory Fitness in Association with Improvements in CD4+T Cell and Skeletal Muscle Mitochondrial Metabolism.” In Arthritis & Rheumatology, Vol. 72, 2020.
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    • Andonian, Brian J., David B. Bartlett, Monica J. Hubal, Leslie Willis, Megan A. Reaves, William E. Kraus, and Kim M. Huffman. “Skeletal Muscle Metabolic Gene Profile Associates With Rheumatoid Arthritis Improvements Following High Intensity Interval Training.” In Medicine and Science in Sports and Exercise, 52:91–91, 2020.
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    • Andonian, Brian, David Bartlett, Deborah Muoio, Timothy Koves, Olga Ilkayeva, Andrew Hoselton, Megan Reaves, William Kraus, and Kim Huffman. “High Intensity Interval Training Improves Rheumatoid Arthritis Cardiorespiratory Fitness and Systemic Inflammation in Association with Alterations in Skeletal Muscle Metabolomic Profiles.” In Arthritis & Rheumatology, Vol. 71, 2019.
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    • Leverenz, David, Jon Golenbiewski, Brian Andonian, Katherine Kaufman, Philip Chu, Mithunan Maheswaranathan, Andrew Johannemann, Jayanth Doss, and Lisa Criscione-Schreiber. “A Quality Improvement Project to Increase Documentation Efficiency in an Academic Rheumatology Practice.” In Arthritis & Rheumatology, Vol. 71, 2019.
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    • Andonian, Brian J., Ching-Heng Chou, Virginia B. Kraus, William E. Kraus, and Kim M. Huffman. “Plasma Mir-146a-5p Associates with Beneficial Body Composition and Plasma Metabolic Profiles in Rheumatoid Arthritis.” In Arthritis & Rheumatology, Vol. 70. WILEY, 2018.
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    • Jessee, Ryan, Stephanie L. Giattino, Atul Kapila, Katherine Kaufman, Jon Golenbiewski, Brian J. Andonian, David Leverenz, and Lisa Criscione-Schreiber. “A Quality Improvement Initiative to Increase Adherence to Hydroxychloroquine Dosing Guidelines at an Academic Medical Center.” In Arthritis & Rheumatology, Vol. 70, 2018.
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    • Andonian, Brian J., David Bartlett, Virginia B. Kraus, Janet Huebner, William E. Kraus, and Kim M. Huffman. “Skeletal Muscle Cytokine and Myostatin Responses to High-Intensity Interval Training in Rheumatoid Arthritis Contrasted with Prediabetes Mellitus.” In Arthritis & Rheumatology, Vol. 69. WILEY, 2017.
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    • Andonian, Brian J., David Bartlett, Virginia B. Kraus, Janet Huebner, William E. Kraus, and Kim M. Huffman. “Serum Galectin-3 in Rheumatoid Arthritis Compared with Healthy Controls and Subjects with Prediabetes before and after High-Intensity Interval Training.” In Arthritis & Rheumatology, Vol. 69. WILEY, 2017.
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    • Andonian, B., W. Rauch, and V. Bhise. “Driver steering performance using Joystick vs. Steering wheel controls.” In Sae Technical Papers, 2003. https://doi.org/10.4271/2003-01-0118.
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