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Jane Elizabeth Blood-Siegfried

Clinical Professor Emerita in the School of Nursing
School of Nursing
Box 3322 Med Ctr, Durham, NC 27710
School of Nursing, Durham, NC 27710

Selected Publications


Exercise as medicine: Providing practitioner guidance on exercise prescription

Journal Article Preventive Medicine Reports · June 1, 2021 The purpose of this study was to examine the effect of a practitioner education program (consisting of education on exercise guidelines and exercise prescription) on practitioner (i) confidence in prescribing exercise and (ii) rate of prescribing exercise. ... Full text Cite

A Continued Professional Development Nursing Partnership in a Remote Bolivian Hospital.

Journal Article Journal of continuing education in nursing · March 2021 Bolivia's recent enactment of universal health care to increase access and delivery of health services can increase health care demands in underresourced, rural communities. We describe how a global intradisciplinary partnership assessed changing health ca ... Full text Cite

Early Peanut Protein Introduction in Clinical Practice.

Journal Article Journal of pediatric nursing · November 2020 PurposeNew multiple agency recommendations have encouraged the early introduction of peanut protein (PP) in high-risk children to decrease peanut allergies. However, many providers are hesitant to use these recommendations. Our objective was to in ... Full text Cite

Virtual Orientation of Volunteer Short-Term International Health Teams to Increase Self-Confidence and Cultural and Global Health Competence.

Journal Article Journal of continuing education in nursing · January 2019 International health team volunteers frequently arrive at service sites with considerable lack of confidence and knowledge gaps because of poor preparation. Preservice orientation has been shown to improve knowledge, confidence, and competence, but current ... Full text Cite

Using Motivational Interviewing to Impact Readiness of RNs to Return to the Classroom.

Journal Article The Journal of nursing administration · June 2018 Supporting nurses with associate degrees in nursing (ADNs) to return to school is challenging for nurse executives. Strategies include tuition reimbursement, scholarships, and flexible scheduling. Despite these measures, it is anticipated that we will fall ... Full text Cite

Implementation of attention-deficit/hyperactivity disorder guidelines in an urban pediatric primary care clinic

Journal Article Journal of Clinical Outcomes Management · April 1, 2018 Background: Approximately 11% of children in the United States ages 4 to 17 have received the diagnosis of attention-deficit hyperactive disorder (ADHD). There are disproportionately higher rates of the diagnosis and fewer child psychiatrists available in ... Cite

Helping Babies Breathe implementation in Zanzibar, Tanzania.

Journal Article International journal of nursing practice · August 2017 AimTo assess the efficacy and feasibility of implementing Helping Babies Breathe, a neonatal resuscitation programme for resource-limited environments.BackgroundThis quality improvement project focused on training midwives on Helping Babi ... Full text Cite

Descriptive study of nursing scope of practice in rural medically underserved areas of Africa, South of the Sahara

Journal Article International Journal of Africa Nursing Sciences · January 1, 2017 Aims The aims of this study are to describe the scope of “non-nursing duties” carried out by nurses, in rural low-resource regions of Tanzania, and describe how the role of nurses is viewed in their communities. Background More than 70% of Tanzanians live ... Full text Cite

Implementation of a Sustainable Ventilator-Associated Pneumonia Prevention Protocol in a Pediatric Intensive Care Unit in Managua, Nicaragua.

Journal Article Dimensions of critical care nursing : DCCN · November 2016 BackgroundVentilator-associated pneumonia (VAP) is a common nosocomial infection in pediatric intensive care units (ICUs). Ventilator-associated pneumonia protocols decrease the incidence of VAP; however, many components of these protocols are not ... Full text Cite

The Impact of Nurses on Neglected Tropical Disease Management.

Journal Article Public health nursing (Boston, Mass.) · November 2015 Although Neglected Tropical Diseases (NTDs) are largely endemic in the developing nations of Africa, Asia, and South and Central America, they are reemerging with increasing frequency in developed countries. Their diagnosis, treatment, and control are an i ... Full text Cite

Coalition Building for Health: A Community Garden Pilot Project with Apartment Dwelling Refugees.

Journal Article Journal of community health nursing · July 2015 Refugees often experience compromised health from both pre- and post-migration stressors. Coalition theory has helped guide the development of targeted programs to address the health care needs of vulnerable populations. Using the Community Coalition Actio ... Full text Cite

Animal models for assessment of infection and inflammation: Contributions to elucidating the pathophysiology of sudden infant death syndrome

Journal Article Frontiers in Immunology · January 1, 2015 Sudden infant death syndrome (SIDS) is still not well understood. It is defined as the sudden and unexpected death of an infant without a definitive cause. There are numerous hypotheses about the etiology of SIDS but the exact cause or causes have never be ... Full text Cite

Intraoperative implementation of a tissue sealant on all lung surgery patients: A quality improvement project

Journal Article Clinical Scholars Review · January 1, 2015 More than 200,000 patients undergo pulmonary surgery annually. Air leaks after pulmonary surgery are a common complication and represent a substantial clinical problem. Air leaks can increase chest tube time, increase pain, reduce mobility, and increase ho ... Full text Cite

Increasing HPV vaccination series completion rates via text message reminders.

Journal Article Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners · July 2014 Human papillomavirus (HPV) is the most frequently diagnosed sexually transmitted infection in the United States. It is associated with the development of cervical, anal-genital, and oral-pharyngeal cancers. The rate of HPV infection among adolescents and y ... Full text Cite

Childhood obesity: Can electronic medical records customized with clinical practice guidelines improve screening and diagnosis?

Journal Article Journal of the American Academy of Nurse Practitioners · August 2012 Purpose: The purpose of this project was to determine if customization of the electronic medical record (EMR) using evidence-based practice guidelines developed by the National Association of Pediatric Nurse Practitioners and the Expert Panel recommendatio ... Full text Cite

Providers as weight coaches: using practice guides and motivational interview to treat obesity in the pediatric office.

Journal Article Journal of pediatric nursing · October 2011 Motivational interview techniques combined with an evidence-based guideline provide valuable tools for the treatment of childhood obesity. The National Association of Pediatric Nurse Practitioners' Healthy Eating and Activity Together guidelines were adopt ... Full text Cite

Autism spectrum disorder screening in primary care.

Journal Article Journal of developmental and behavioral pediatrics : JDBP · January 2011 ObjectivesOne in 110 children in the United States has autism spectrum disorder (ASD). Early identification and early intervention have been shown to improve outcomes for children with ASD. Although recommended, routine ASD screening at 18 and 24 ... Full text Cite

The long-term effects of prenatal nicotine exposure on neurologic development.

Journal Article Journal of midwifery & women's health · March 2010 A large body of documented evidence has found that smoking during pregnancy is harmful to both the mother and the fetus. Prenatal exposure to nicotine in various forms alters neurologic development in experimental animals and may increase the risk for neur ... Full text Cite

Is shock a key element in the pathology of sudden infant death syndrome (SIDS)?

Journal Article Biological research for nursing · October 2009 In developed countries, sudden infant death syndrome (SIDS) is the most common cause of death for infants between 1 month and 1 year of age. The etiology of SIDS is likely to be multifactorial, and current paradigms often describe three overlapping element ... Full text Cite

The role of infection and inflammation in sudden infant death syndrome.

Journal Article Immunopharmacology and immunotoxicology · January 2009 Sudden Infant Death Syndrome (SIDS) is the most common cause of post-neonatal mortality in the developed world. The exact cause of SIDS is likely to be multifactorial involving a critical developmental period, a vulnerable infant, and one or more triggers. ... Full text Cite

Animal models of sudden infant death syndrome

Journal Article · December 1, 2008 Sudden infant death syndrome (SIDS) is the most common cause of postneonatal infant mortality in the developed world. It is a diagnosis of exclusion, defined as the sudden and unexplained death of an infant between 1 month and 1 year of life. Examination o ... Full text Cite

Evidence for infection, inflammation and shock in sudden infant death: parallels between a neonatal rat model of sudden death and infants who died of sudden infant death syndrome.

Journal Article Innate immunity · June 2008 This study compared pathological findings from a neonatal rat model of sudden death with those from 40 sudden infant death syndrome (SIDS) infants collected at autopsy. In the rat model, influenza A virus was administered intranasally on postnatal day 10, ... Full text Cite

A rubric for improving the quality of online courses.

Journal Article International journal of nursing education scholarship · January 2008 All of the graduate students in the School of Nursing take some of their Master of Science courses online. A group of six School of Nursing faculty members and a graduate student received funding to determine best practices in online courses. The group dev ... Full text Cite

To Screen or Not to Screen: Complexities of Newborn Screening in the 21st Century

Journal Article Journal for Nurse Practitioners · January 1, 2006 Newborn screening is a routine occurrence in every newborn nursery; however, there are many things that the practicing nurse practitioner may not be aware of. What is the appropriate process for screening newborns? What tests are included in the state wher ... Full text Cite

Neonatal lung remodeling: structural, inflammatory, and ventilator-induced injury.

Journal Article The Journal of perinatal & neonatal nursing · October 2005 The developing lung is subject to events, both prenatal and postnatal, that alter the normal developmental process. The degree of insult or injury affects how the lung functions at birth and then responds to the insult throughout childhood. In this article ... Full text Cite

Alteration in regulation of inflammatory response to influenza a virus and endotoxin in suckling rat pups: a potential relationship to sudden infant death syndrome.

Journal Article FEMS immunology and medical microbiology · September 2004 Featured Publication Data increasingly implicate a possible role of immune and inflammatory responses to infection in sudden infant death syndrome (SIDS). We have previously described a dual challenge model that results in pathology, organ damage, vascular collapse and unexpla ... Full text Cite

Animal models of sudden unexplained death.

Journal Article FEMS immunology and medical microbiology · September 2004 Featured Publication The etiology of sudden infant death syndrome (SIDS) is unknown but thought to be multifactorial. Several animal models have been developed that induce death without pre-existing symptoms and with pathology similar to that seen in SIDS infants; however, the ... Full text Cite

Synergistic effect of influenza a virus on endotoxin-induced mortality in rat pups: a potential model for sudden infant death syndrome.

Journal Article Pediatric research · October 2002 Featured Publication Sudden infant death syndrome is the most common cause of postneonatal infant mortality in the developed world. It is a diagnosis of exclusion with peak age of incidence between 2 and 6 mo. Fifty to 63% of these infants have a preexisting upper respiratory ... Full text Cite

Sudden infant death syndrome: a toxic response.

Journal Article AACN clinical issues · May 2000 Featured Publication Causes of sudden infant death syndrome (SIDS) remain elusive. Much of the current literature points to an infectious cause with a role for proinflammatory cytokines and septic shock in stimulating an overwhelming response in an infant. This article reviews ... Full text Cite

A historical perspective on the discovery of adenyl purines.

Journal Article Biological research for nursing · April 2000 Featured Publication In 1929, Drury and Szent-Gyorgyi described the effects of a simple extract of heart muscle and other tissues on the mammalian heart. This extract was identified as adenylic acid and found to have profound effects on the cardiovascular system. The discovery ... Full text Cite

Monokine production following in vitro stimulation of the THP-1 human monocytic cell line with pertussis vaccine components.

Journal Article Journal of clinical immunology · January 1998 Featured Publication Whole-cell pertussis found in diphtheria-tetanus-pertussis (DTP) vaccine can produce symptoms reminiscent of biological responses to circulating proinflammatory monokines such as IL-6, IL-1beta, and TNFalpha. Therefore the ability of pertussis-containing v ... Full text Cite

The challenges of early discharge. Common newborn problems in the first few weeks of life.

Journal Article Advance for nurse practitioners · January 1998 Featured Publication In a thorough discussion of a published series on early discharge, Britton, Britton and Beebe note that methodological limitations, study design problems and heterogeneity sorely limit the conclusions that may be drawn from published studies about early di ... Cite