https://orcid.org/0000-0002-8347-7992
Overview
Kantor Lab, the Duke University Viral Vector Core, facilitates the use of virus-mediated tools for gene transfer by investigators across diverse fields of study such as systems neuroscience, stem cell biology, metabolism, aging, cancer biology and others. Services are open to researchers within the Duke University Medical Center, Duke University, as well as outside investigators, worldwide.
Current Appointments & Affiliations
Adjunct Professor in the Department of Neurobiology
·
2025 - Present
Neurobiology,
Basic Science Departments
Faculty Network Member of the Duke Institute for Brain Sciences
·
2019 - Present
Duke Institute for Brain Sciences,
University Institutes and Centers
Recent Publications
CRISPR-Cas editing technologies for viral-mediated gene therapies of human diseases: Mechanisms, progress, and challenges.
Journal Article Mol Ther Nucleic Acids · March 12, 2026 The gene therapy landscape has evolved substantially in recent years, beginning with the approval of the first adeno-associated virus-based gene therapy, Luxterna, in 2017. Since then, the US FDA has approved nearly 30 new viral gene therapy programs, with ... Full text Link to item CiteTrends and challenges of AAV-delivered gene editing therapeutics for CNS disorders: Implications for neurodegenerative disease.
Journal Article Mol Ther Nucleic Acids · September 9, 2025 Recent advances in gene-editing technologies offer new opportunities for drug development to treat unmet medical needs in central nervous system (CNS) disorders including neurogenerative diseases of the aging brain. The adeno-associated virus (AAV) is a pr ... Full text Link to item CiteThe therapeutic implications of all-in-one AAV-delivered epigenome-editing platform in neurodegenerative disorders.
Journal Article Nat Commun · August 23, 2024 Safely and efficiently controlling gene expression is a long-standing goal of biomedical research, and CRISPR/Cas system can be harnessed to create powerful tools for epigenetic editing. Adeno-associated-viruses (AAVs) represent the delivery vehicle of cho ... Full text Link to item CiteRecent Grants
Untangling the diversity in the genetic architecture of late-onset Alzheimer's disease using single cell multi-omics
ResearchCo Investigator · Awarded by National Institutes of Health · 2022 - 2027A novel gene-therapy strategy for Parkinson's disease (PD): Epigenome editing mediated-regulation of SNCA expression
ResearchCo-Principal Investigator · Awarded by Michael J. Fox Foundation for Parkinson's Research · 2022 - 2025Design and production of adeno-associated vectors (AAV) for Kallyope
ResearchPrincipal Investigator · Awarded by Kallyope, Inc · 2023 - 2025View All Grants
Education
The Hebrew University of Jerusalem (Israel) ·
2005
Ph.D.
The Hebrew University of Jerusalem (Israel) ·
1998
M.Sc.
Grodno State Medical University (Republic of Belarus) ·
1995
Ph.D.