Scholars@Duke
Brian McCourt

Brian McCourt

Senior Dir, IT
Duke Clinical Research Institute
brian.mccourt@duke.edu
Box 3850 Med Ctr, Durham, NC
300 W. Morgan Street, Durham, NC 27701

Selected Publications

Doing it right: Caring for and protecting patient information for US organ donors and transplant recipients.

Journal Article Patterns (N Y) · April 14, 2023 In the current US organ transplantation system, there are no regulations defining how organ procurement organizations must manage personal data and protect the privacy of donors and recipients. In response to the recent announcement of a major overhaul of ... Full text Link to item Cite

Reimagining the United States organ procurement and transplant network

Journal Article Frontiers in Transplantation · January 1, 2023 The United States system of solid organ transplantation is overseen by the Organ Procurement Transplantation Network (OPTN). Recent announcements from the Health Resources and Services Administration (HRSA) indicate their clear intention to reform the syst ... Full text Cite

Design of the Healthcare Worker Exposure Response and Outcomes (HERO) research platform.

Journal Article Contemp Clin Trials · October 2021 BACKGROUND: The SARS CoV-2 virus has caused one of the deadliest pandemics in recent history, resulting in over 170 million deaths and global economic disruption. There remains an urgent need for clinical trials to test therapies for treatment and preventi ... Full text Open Access Link to item Cite

Supporting open access to clinical trial data for researchers: The Duke Clinical Research Institute-Bristol-Myers Squibb Supporting Open Access to Researchers Initiative.

Journal Article Am Heart J · February 2016 There are growing calls for sponsors to increase transparency by providing access to clinical trial data. In response, Bristol-Myers Squibb and the Duke Clinical Research Institute have collaborated on a new initiative, Supporting Open Access to Researcher ... Full text Link to item Cite

Meaningful Use of Electronic Health Records: Experiences From the Field and Future Opportunities.

Journal Article JMIR medical informatics · September 2015 BackgroundWith the aim of improving health care processes through health information technology (HIT), the US government has promulgated requirements for "meaningful use" (MU) of electronic health records (EHRs) as a condition for providers receiv ... Full text Cite

A registry-based randomized trial comparing radial and femoral approaches in women undergoing percutaneous coronary intervention: the SAFE-PCI for Women (Study of Access Site for Enhancement of PCI for Women) trial.

Journal Article JACC Cardiovasc Interv · August 2014 OBJECTIVES: This study sought to determine the effect of radial access on outcomes in women undergoing percutaneous coronary intervention (PCI) using a registry-based randomized trial. BACKGROUND: Women are at increased risk of bleeding and vascular compli ... Full text Link to item Cite

The database for aggregate analysis of ClinicalTrials.gov (AACT) and subsequent regrouping by clinical specialty.

Journal Article PLoS One · 2012 BACKGROUND: The ClinicalTrials.gov registry provides information regarding characteristics of past, current, and planned clinical studies to patients, clinicians, and researchers; in addition, registry data are available for bulk download. However, issues ... Full text Link to item Cite

Standardising clinical data elements

Journal Article International Journal of Functional Informatics and Personalised Medicine · January 1, 2010 We report the development and implementation of a methodology for standardising clinical data elements. The methodology, piloted using Tuberculosis (TB) and Acute Coronary Syndromes (ACS) domains, relies on clinicians for natural language definitions and o ... Full text Cite

Making sense of standards.

Journal Article J AHIMA · September 2007 Link to item Cite

Data standards: At the intersection of sites, clinical research networks, and standards development initiatives

Journal Article Drug Information Journal · January 1, 2007 Interactions between the health care and clinical research communities are currently inefficient. The present environment forces unnecessary redundancy, from the capture of patient data in the clinician-patient encounter to multiple uses of that data. Clin ... Full text Cite

Comparison of sibrafiban with aspirin for prevention of cardiovascular events after acute coronary syndromes: a randomised trial. The SYMPHONY Investigators. Sibrafiban versus Aspirin to Yield Maximum Protection from Ischemic Heart Events Post-acute Coronary Syndromes.

Journal Article Lancet · January 29, 2000 BACKGROUND: Aspirin lowers risks of death and myocardial infarction in patients with acute coronary syndromes. Intravenous glycoprotein IIb/IIIa receptor antagonists further reduce the rates of ischaemic events in these patients, but the efficacy of long-t ... Link to item Cite

Determinants of abnormal gonadotropin secretion in clinically defined women with polycystic ovary syndrome.

Journal Article The Journal of clinical endocrinology and metabolism · July 1997 UnlabelledPolycystic ovary syndrome (PCOS) is a heterogeneous disorder of reproductive age women characterized in its broadest definition by the presence of oligoamenorrhea and hyperandrogenism and the absence of other disorders. Defects of gonado ... Full text Cite

Determinants of Abnormal Gonadotropin Secretion in Clinically Defined Women with Polycystic Ovary Syndrome1

Journal Article The Journal of Clinical Endocrinology & Metabolism · July 1, 1997 Polycystic ovary syndrome (PCOS) is a heterogeneous disorder of reproductive age women characterized in its broadest definition by the presence of oligoamenorrhea and hyperandrogenism and the absence of other disorders. Defects of gonadotropin secr ... Full text Cite