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Brita Katherine Boyd

Assistant Professor of Obstetrics and Gynecology
Obstetrics and Gynecology, Maternal Fetal Medicine
Box 3967 Med Ctr, Durham, NC 27710
Duke Perinatal Durham, 2608 Erwin Rd, Suite 200, Durham, NC 27705

Selected Publications


Transabdominal Fetal Ultrasound Before Early-Term Planned Delivery for Norrie Disease.

Journal Article J Vitreoretin Dis · 2024 Purpose: To describe a case of early-term planned delivery of a fetus with Norrie disease. Methods: A retrospective chart review was performed. Results: A fetus with an older sibling with bilateral blindness from Norrie disease had positive NPD genetic tes ... Full text Link to item Cite

Validation of a sonographic checklist for the detection of histologic placenta accreta spectrum.

Journal Article Am J Obstet Gynecol MFM · August 2023 BACKGROUND: To standardize research terminology and to reduce unanticipated placenta accreta spectrum, the European Working Group for Abnormally Invasive Placenta developed a consensus checklist for reporting suspected placenta accreta spectrum observed du ... Full text Link to item Cite

Sonographic Evaluation of the Placenta in Fontan Patients: A Case Series.

Journal Article J Ultrasound Med · June 2023 Due to the advancements in pediatric cardiothoracic surgery and medical management, more individuals with congenital heart disease are reaching reproductive age. It is well established that individuals with Fontan circulation are at an increased risk for m ... Full text Link to item Cite

Abnormalities of the Fetal Central Nervous System: Prenatal US Diagnosis with Postnatal Correlation.

Journal Article Radiographics · 2020 Fetal central nervous system (CNS) abnormalities are second only to cardiac malformations in their frequency of occurrence. Early and accurate diagnosis at prenatal US is therefore essential, allowing improved prenatal counseling and facilitating appropria ... Full text Link to item Cite

A Genocentric Approach to Discovery of Mendelian Disorders.

Journal Article Am J Hum Genet · November 7, 2019 The advent of inexpensive, clinical exome sequencing (ES) has led to the accumulation of genetic data from thousands of samples from individuals affected with a wide range of diseases, but for whom the underlying genetic and molecular etiology of their cli ... Full text Open Access Link to item Cite

Can we improve the gestation-adjusted projection (GAP) method for prediction of birth weight in morbidly obese women?

Journal Article J Matern Fetal Neonatal Med · November 2019 Objective: The gestation-adjusted projection (GAP) is a method to predict birthweight using population birth data and third trimester ultrasound fetal weight. This method usually utilizes population birth weight data from almost 40 years ago. In 2011, a la ... Full text Link to item Cite

Pharmacologic Treatment of Diabetes in Pregnancy.

Journal Article Obstet Gynecol Surv · May 2019 IMPORTANCE: Diabetes affects 6% to 9% of pregnancies, with gestational diabetes mellitus accounting for more than 90% of cases. Pregestational and gestational diabetes are associated with significant maternal and fetal risks; therefore, screening and treat ... Full text Link to item Cite

Mutations in NCAPG2 Cause a Severe Neurodevelopmental Syndrome that Expands the Phenotypic Spectrum of Condensinopathies.

Journal Article Am J Hum Genet · January 3, 2019 The use of whole-exome and whole-genome sequencing has been a catalyst for a genotype-first approach to diagnostics. Under this paradigm, we have implemented systematic sequencing of neonates and young children with a suspected genetic disorder. Here, we r ... Full text Open Access Link to item Cite

Clinical Utility of Fetal Short-Lag Spatial Coherence Imaging.

Journal Article Ultrasound Med Biol · April 2018 In this study, we evaluate the clinical utility of fetal short-lag spatial coherence (SLSC) imaging. Previous work has documented significant improvements in image quality with fetal SLSC imaging as quantified by measurements of contrast and contrast-to-no ... Full text Link to item Cite

Ultrasound Examination of the Fetal Heart.

Journal Article Obstet Gynecol Surv · January 2017 Congenital heart disease (CHD) occurs in 4-13 per 1000 births in the United States. While many risk factors for CHD have been identified, more than 90% of cases occur in low-risk patients. Guidelines for fetal cardiac screening during the second trimester ... Full text Link to item Cite

Prediction of birthweight from third-trimester ultrasound in morbidly obese women.

Journal Article Am J Obstet Gynecol · October 2014 OBJECTIVE: The gestation-adjusted projection method (GAP method) uses third trimester ultrasound fetal weight to predict birthweight. Our study sought to assess if the accuracy of the GAP method in morbidly obese women depended on (1) ultrasound timing or ... Full text Link to item Cite

Dichorionic, diamnionic twin pregnancy discordant for anencephaly: Report of two cases and literature review.

Journal Article Radiol Case Rep · 2013 Anencephaly is a lethal diagnosis. In the unique situation of a twin pregnancy discordant for anencephaly, early ultrasound diagnosis based on the discrepancy in the appearance of the heads can facilitate management and potentially decrease morbidity and m ... Full text Link to item Cite

Cervicovaginal fistula presenting during miscarriage.

Journal Article Ultrasound Obstet Gynecol · July 2010 Cervicovaginal fistula is a recognized complication of induced mid-trimester termination of pregnancy, but more recently it has also been recognized as representing a complication of prior cervical cerclage. We report the ultrasound findings of prolapse of ... Full text Link to item Cite

Sonohysterography: do 3D reconstructed images provide additional value?

Journal Article AJR Am J Roentgenol · April 2008 OBJECTIVE: The purpose of this study was to retrospectively determine the value of adding 3D multiplanar sonography to 2D sonohysterography. MATERIALS AND METHODS: Between September 2003 and April 2005, 80 women (mean age, 43.5 years; range, 26-78 years) u ... Full text Link to item Cite

Double occupancy.

Journal Article Am J Obstet Gynecol · February 2007 Full text Link to item Cite

Prenatal diagnosis of tetrasomy 9p.

Journal Article Am J Med Genet A · April 30, 2004 Full text Link to item Cite

Trisomy 8 mosaicism: selective growth advantage of normal cells vs. growth disadvantage of trisomy 8 cells.

Journal Article Am J Med Genet A · January 15, 2003 A fetus with trisomy 8 mosaicism was identified prenatally due to an abnormal maternal serum triple screen. Tissue samples were taken at birth to determine the level of trisomy 8 mosaicism found within embryonic and extra-embryonic tissues, rates of cell d ... Full text Link to item Cite

Transabdominal Fetal Ultrasound Before Early-Term Planned Delivery for Norrie Disease.

Journal Article J Vitreoretin Dis · 2024 Purpose: To describe a case of early-term planned delivery of a fetus with Norrie disease. Methods: A retrospective chart review was performed. Results: A fetus with an older sibling with bilateral blindness from Norrie disease had positive NPD genetic tes ... Full text Link to item Cite

Validation of a sonographic checklist for the detection of histologic placenta accreta spectrum.

Journal Article Am J Obstet Gynecol MFM · August 2023 BACKGROUND: To standardize research terminology and to reduce unanticipated placenta accreta spectrum, the European Working Group for Abnormally Invasive Placenta developed a consensus checklist for reporting suspected placenta accreta spectrum observed du ... Full text Link to item Cite

Sonographic Evaluation of the Placenta in Fontan Patients: A Case Series.

Journal Article J Ultrasound Med · June 2023 Due to the advancements in pediatric cardiothoracic surgery and medical management, more individuals with congenital heart disease are reaching reproductive age. It is well established that individuals with Fontan circulation are at an increased risk for m ... Full text Link to item Cite

Abnormalities of the Fetal Central Nervous System: Prenatal US Diagnosis with Postnatal Correlation.

Journal Article Radiographics · 2020 Fetal central nervous system (CNS) abnormalities are second only to cardiac malformations in their frequency of occurrence. Early and accurate diagnosis at prenatal US is therefore essential, allowing improved prenatal counseling and facilitating appropria ... Full text Link to item Cite

A Genocentric Approach to Discovery of Mendelian Disorders.

Journal Article Am J Hum Genet · November 7, 2019 The advent of inexpensive, clinical exome sequencing (ES) has led to the accumulation of genetic data from thousands of samples from individuals affected with a wide range of diseases, but for whom the underlying genetic and molecular etiology of their cli ... Full text Open Access Link to item Cite

Can we improve the gestation-adjusted projection (GAP) method for prediction of birth weight in morbidly obese women?

Journal Article J Matern Fetal Neonatal Med · November 2019 Objective: The gestation-adjusted projection (GAP) is a method to predict birthweight using population birth data and third trimester ultrasound fetal weight. This method usually utilizes population birth weight data from almost 40 years ago. In 2011, a la ... Full text Link to item Cite

Pharmacologic Treatment of Diabetes in Pregnancy.

Journal Article Obstet Gynecol Surv · May 2019 IMPORTANCE: Diabetes affects 6% to 9% of pregnancies, with gestational diabetes mellitus accounting for more than 90% of cases. Pregestational and gestational diabetes are associated with significant maternal and fetal risks; therefore, screening and treat ... Full text Link to item Cite

Mutations in NCAPG2 Cause a Severe Neurodevelopmental Syndrome that Expands the Phenotypic Spectrum of Condensinopathies.

Journal Article Am J Hum Genet · January 3, 2019 The use of whole-exome and whole-genome sequencing has been a catalyst for a genotype-first approach to diagnostics. Under this paradigm, we have implemented systematic sequencing of neonates and young children with a suspected genetic disorder. Here, we r ... Full text Open Access Link to item Cite

Clinical Utility of Fetal Short-Lag Spatial Coherence Imaging.

Journal Article Ultrasound Med Biol · April 2018 In this study, we evaluate the clinical utility of fetal short-lag spatial coherence (SLSC) imaging. Previous work has documented significant improvements in image quality with fetal SLSC imaging as quantified by measurements of contrast and contrast-to-no ... Full text Link to item Cite

Ultrasound Examination of the Fetal Heart.

Journal Article Obstet Gynecol Surv · January 2017 Congenital heart disease (CHD) occurs in 4-13 per 1000 births in the United States. While many risk factors for CHD have been identified, more than 90% of cases occur in low-risk patients. Guidelines for fetal cardiac screening during the second trimester ... Full text Link to item Cite

Prediction of birthweight from third-trimester ultrasound in morbidly obese women.

Journal Article Am J Obstet Gynecol · October 2014 OBJECTIVE: The gestation-adjusted projection method (GAP method) uses third trimester ultrasound fetal weight to predict birthweight. Our study sought to assess if the accuracy of the GAP method in morbidly obese women depended on (1) ultrasound timing or ... Full text Link to item Cite

Dichorionic, diamnionic twin pregnancy discordant for anencephaly: Report of two cases and literature review.

Journal Article Radiol Case Rep · 2013 Anencephaly is a lethal diagnosis. In the unique situation of a twin pregnancy discordant for anencephaly, early ultrasound diagnosis based on the discrepancy in the appearance of the heads can facilitate management and potentially decrease morbidity and m ... Full text Link to item Cite

Cervicovaginal fistula presenting during miscarriage.

Journal Article Ultrasound Obstet Gynecol · July 2010 Cervicovaginal fistula is a recognized complication of induced mid-trimester termination of pregnancy, but more recently it has also been recognized as representing a complication of prior cervical cerclage. We report the ultrasound findings of prolapse of ... Full text Link to item Cite

Sonohysterography: do 3D reconstructed images provide additional value?

Journal Article AJR Am J Roentgenol · April 2008 OBJECTIVE: The purpose of this study was to retrospectively determine the value of adding 3D multiplanar sonography to 2D sonohysterography. MATERIALS AND METHODS: Between September 2003 and April 2005, 80 women (mean age, 43.5 years; range, 26-78 years) u ... Full text Link to item Cite

Double occupancy.

Journal Article Am J Obstet Gynecol · February 2007 Full text Link to item Cite

Prenatal diagnosis of tetrasomy 9p.

Journal Article Am J Med Genet A · April 30, 2004 Full text Link to item Cite

Trisomy 8 mosaicism: selective growth advantage of normal cells vs. growth disadvantage of trisomy 8 cells.

Journal Article Am J Med Genet A · January 15, 2003 A fetus with trisomy 8 mosaicism was identified prenatally due to an abnormal maternal serum triple screen. Tissue samples were taken at birth to determine the level of trisomy 8 mosaicism found within embryonic and extra-embryonic tissues, rates of cell d ... Full text Link to item Cite

MR imaging findings in fetal goiter caused by maternal graves disease.

Journal Article J Comput Assist Tomogr · 2002 Antenatal diagnosis of fetal goiter should be appropriately managed to avoid perinatal complications. Here, we present the MR imaging features of a fetal goiter caused by maternal Graves disease. Diffusely enlarged fetal thyroid gland was seen showing homo ... Full text Link to item Cite

Delayed postpartum hemorrhage: A retrospective analysis

Journal Article Journal of Maternal-Fetal and Neonatal Medicine · January 1, 1995 This investigation sought to characterize the syndrome of severe delayed postpartum hemorrhage. We defined the syndrome as hemorrhage requiring hospitalization and/or surgical intervention, occurring after the patients' initial hospital discharge. We evalu ... Full text Cite