Journal ArticleDiabetes Ther · November 2024
INTRODUCTION: Patients with type 2 diabetes (T2D), particularly those from historically marginalized racial and ethnic groups, are at high risk of poor outcomes from metabolic dysfunction-associated steatotic liver disease (MASLD). Evidence-based managemen ...
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Journal ArticleEndocr Pract · July 2024
OBJECTIVE: To assess frequency of evidence-based management (EBM) of metabolic dysfunction-associated steatotic liver disease (MASLD) in patients with type 2 diabetes (T2D), and to examine for racial/ethnic disparities in the receipt of EBM. METHODS: We co ...
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Journal ArticleSouth Med J · April 2024
OBJECTIVES: Eradication of Helicobacter pylori reduces the risk of gastric cancer (GC). Individuals with type 2 diabetes mellitus (T2DM) are known to be at increased risk for GC. In a cohort of H. pylori-positive individuals, we assessed whether those with ...
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Journal ArticleBMJ Open Diabetes Res Care · November 29, 2023
INTRODUCTION: Metabolic dysfunction-associated steatohepatitis (MASH) is highly prevalent in type 2 diabetes (T2D). Pioglitazone and glucagon-like peptide-1 receptor agonists (GLP-1RA) are medications used in T2D that can resolve MASH and should be conside ...
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Journal ArticleDiabetes Care · November 1, 2023
OBJECTIVE: To evaluate the relationship between social needs and metformin use among adults with type 2 diabetes (T2D). RESEARCH DESIGN AND METHODS: In a prospective cohort study of adults with T2D (n = 722), we linked electronic health record (EHR) and Su ...
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Journal ArticleJ Am Geriatr Soc · June 2023
Whether initiation of statins could increase survival free of dementia and disability in adults aged ≥75 years is unknown. PREVENTABLE, a double-blind, placebo-controlled randomized pragmatic clinical trial, will compare high-intensity statin therapy (ator ...
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Journal ArticleJ Telemed Telecare · May 25, 2023
This article highlights the benefits of electronic-consultations and outlines steps for a primary care-centered approach to implementation. We include descriptions of traditional and electronic-consultation delivery models from the perspective of referring ...
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Journal ArticleJ Endocr Soc · March 6, 2023
OBJECTIVE: Examine factors associated with increased diabetes distress (DD) among patients with type 2 diabetes with DD assessed by Diabetes Distress Scale (DDS) total and subscale scores (emotional burden, physician-related distress, regimen-related distr ...
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Journal ArticleJMIR Res Protoc · October 11, 2022
BACKGROUND: Health care providers are increasingly screening patients for unmet social needs (eg, food, housing, transportation, and social isolation) and referring patients to relevant community-based resources and social services. Patients' connection to ...
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Journal ArticleCurr Opin Endocrinol Diabetes Obes · October 1, 2021
PURPOSE OF REVIEW: Obesity and diabetes contribute to chronic kidney disease (CKD) and accelerate the loss of kidney function. Low carbohydrate diets (LCDs) are associated with weight loss and improved diabetes control. Compared to the typical Western diet ...
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Journal ArticlePatient Educ Couns · August 2021
OBJECTIVES: Examine the association of patient perceptions of care with hemoglobin A1c (HbA1c), medication adherence, and missed appointments in non-Hispanic Black (NHB) and White (NHW) patients with type 2 diabetes (T2DM). METHODS: We used linear and logi ...
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Journal ArticleJ Med Internet Res · January 20, 2021
BACKGROUND: Type 2 diabetes affects 30 million Americans, representing a significant cause of morbidity and mortality. Self-management support is an important component of chronic illness care and is a key pillar of the chronic care model. Face-to-face tea ...
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Journal ArticleHealth equity · January 2021
Purpose: Research suggests that providers contribute to racial disparities in health outcomes. Identifying modifiable provider perspectives that are associated with decreased racial disparities will help in the design of effective educational interv ...
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Journal ArticleWomens Health Rep (New Rochelle) · 2020
UNLABELLED: Background: Obesity prevalence is higher in women veterans overall than their civilian counterparts considering 44% of women veterans are obese. Thus, there is a critical need to understand the facilitators and barriers to women veterans' parti ...
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Journal Article · December 18, 2019
BACKGROUNDType 2 diabetes affects 30 million Americans, representing a significant cause of morbidity and mortality. Self-management support is an important component of chronic illness c ...
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Journal ArticleBMC Public Health · May 17, 2019
BACKGROUND: For patients with obesity who are not ready for or experience barriers to weight loss, clinical practice guidelines recommend provider counseling on preventing further weight gain as a first-line treatment approach. Unfortunately, evidence-base ...
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Journal ArticlePrev Chronic Dis · March 28, 2019
INTRODUCTION: Neighborhood characteristics such as racial segregation may be associated with hypertension, but studies have not examined these relationships using spatial models appropriate for geographically patterned health outcomes. The objectives of ou ...
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Journal ArticleCurr Diab Rep · February 26, 2019
PURPOSE OF REVIEW: Moderate hypertriglyceridemia is exceedingly common in diabetes, and there is growing evidence that it contributes to residual cardiovascular risk in statin-optimized patients. Major fibrate trials yielded inconclusive results regarding ...
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Journal ArticleAm J Prev Med · December 2018
INTRODUCTION: Obesity treatment is less successful for socioeconomically disadvantaged populations, particularly when delivered in primary care. Digital health strategies can extend the reach of clinical obesity treatments to care settings serving patients ...
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Journal ArticleJMIR Mhealth Uhealth · October 18, 2018
BACKGROUND: Understanding how engagement in mobile health (mHealth) weight loss interventions relates to weight change may help develop effective intervention strategies. OBJECTIVE: This study aims to examine the (1) patterns of participant engagement over ...
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Journal Article · March 22, 2018
BACKGROUNDUnderstanding how engagement in mobile health (mHealth) weight loss interventions relates to weight change may help develop effective intervention strategies.
...
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Journal ArticleJ Womens Health (Larchmt) · January 2018
BACKGROUND: Few evaluations of the Veterans Health Administration Motivating Overweight/Obese Veterans Everywhere (MOVE!) weight management program have assessed 6-month weight change or factors associated with weight change by gender. MATERIALS AND METHOD ...
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Journal ArticleAnn Behav Med · August 2017
BACKGROUND: Obesity and poor sleep are highly prevalent among Black women. PURPOSE: We examined whether a weight gain prevention intervention improved sleep among Black women. METHODS: We conducted a randomized trial comparing a 12-month weight gain preven ...
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Journal ArticleJ Womens Health (Larchmt) · July 2017
BACKGROUND: Compared with men, women have poorer lipid control. Although potential causes of this disparity have been explored, it is unknown whether patient-centered factors such as satisfaction and confidence contribute. We evaluated (1) whether satisfac ...
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Journal ArticleJ Am Med Inform Assoc · April 1, 2017
OBJECTIVE: We assessed the sensitivity and specificity of 8 electronic health record (EHR)-based phenotypes for diabetes mellitus against gold-standard American Diabetes Association (ADA) diagnostic criteria via chart review by clinical experts. MATERIALS ...
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Journal ArticleAm J Clin Nutr · February 2017
BACKGROUND: Low-normal potassium is a risk factor for diabetes and may account for some of the racial disparity in diabetes risk. Aldosterone affects serum potassium and is associated with insulin resistance. OBJECTIVES: We sought to confirm the associatio ...
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Journal ArticleAnn Behav Med · February 2017
BACKGROUND: Regular physical activity is important for improving and maintaining health, but sedentary behavior is difficult to change. Providing objective, real-time feedback on physical activity with wearable motion-sensing technologies (activity monitor ...
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Journal ArticleWomens Health Issues · 2017
BACKGROUND: Women veterans are at increased risk for cardiovascular disease (CVD), but little is known about comorbidities and healthcare preferences associated with CVD risk in this population. METHODS: We describe the prevalence of CVD-relevant health be ...
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Chapter · January 1, 2017
Hypertension is a major risk factor for coronary heart disease, stroke, and premature death and a leading risk factor for global disease burden. Prevalence for those 18 years and older in the United States has remained around 29% since 1999 with little imp ...
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Journal ArticleClin Kidney J · August 2016
BACKGROUND: Although the Dietary Approaches to Stop Hypertension (DASH) diet lowers blood pressure (BP) for adults with normal kidney function, evidence is lacking regarding its safety and efficacy in chronic kidney disease (CKD). We aimed to test the effe ...
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Journal ArticleContemp Clin Trials · May 2016
INTRODUCTION: Obesity continues to disproportionately affect medically vulnerable populations. Digital health interventions may be effective for delivering obesity treatment in low-resource primary care settings. METHODS: Track is a 12-month randomized con ...
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Journal ArticleObesity (Silver Spring) · May 2016
OBJECTIVE: In the Weight Loss Maintenance (WLM) Trial, a personal contact (PC) intervention sustained greater weight loss relative to a self-directed (SD) group over 30 months. This study investigated the effects of continued intervention over an additiona ...
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Journal ArticleContemp Clin Trials · January 2016
BACKGROUND: The Affordable Care Act encourages healthcare systems to integrate behavioral and medical healthcare, as well as to employ electronic health records (EHRs) for health information exchange and quality improvement. Pragmatic research paradigms th ...
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Journal ArticlePLoS One · 2016
The global burden of osteoporotic fractures is associated with significant morbidity, mortality, and healthcare costs. We examined the ClinicalTrials.gov database to determine whether recently registered clinical trials addressed prevention and treatment i ...
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Journal ArticleWomens Health Issues · 2016
BACKGROUND: Women are a rapidly growing segment of patients who seek care in the Veterans Affairs (VA) Healthcare System, yet many questions regarding their health care experiences and outcomes remain unanswered. Racial and ethnic disparities have been wel ...
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Journal ArticleClin Trials · December 2015
BACKGROUND/AIMS: The obesity epidemic has spread to young adults, and obesity is a significant risk factor for cardiovascular disease. The prominence and increasing functionality of mobile phones may provide an opportunity to deliver longitudinal and scala ...
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Journal ArticleDrug Alcohol Depend · November 1, 2015
BACKGROUND: Comorbid diabetes and substance use diagnoses (SUD) represent a hazardous combination, both in terms of healthcare cost and morbidity. To date, there is limited information about the association of SUD and related mental disorders with type 2 d ...
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Journal ArticleObesity (Silver Spring) · November 2015
OBJECTIVE: To determine the effect on weight of two mobile technology-based (mHealth) behavioral weight loss interventions in young adults. METHODS: Randomized, controlled comparative effectiveness trial in 18- to 35-year-olds with BMI ≥ 25 kg/m(2) (overwe ...
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Journal ArticleN Engl J Med · July 16, 2015
BACKGROUND: Data are lacking on the long-term effect on cardiovascular events of adding sitagliptin, a dipeptidyl peptidase 4 inhibitor, to usual care in patients with type 2 diabetes and cardiovascular disease. METHODS: In this randomized, double-blind st ...
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Journal ArticleJ Clin Transl Endocrinol · March 2015
OBJECTIVE: The Durham Diabetes Coalition (DDC) was established in response to escalating rates of disability and death related to type 2 diabetes mellitus, particularly among racial/ethnic minorities and persons of low socioeconomic status in Durham County ...
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Journal ArticleContemp Clin Trials · March 2014
BACKGROUND: The obesity epidemic has spread to young adults, leading to significant public health implications later in adulthood. Intervention in early adulthood may be an effective public health strategy for reducing the long-term health impact of the ep ...
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Journal ArticleCurr Opin Clin Nutr Metab Care · January 2014
PURPOSE OF REVIEW: There is burgeoning evidence that branch chain amino acids (BCAAs) are biomarkers of metabolic, cardiovascular, renal and cerebrovascular disease. The purpose of this review is to summarize the current evidence in this area. RECENT FINDI ...
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Journal ArticleObesity · January 1, 2014
Objective To determine the effect of age on weight loss and weight loss maintenance in participants in the Weight Loss Maintenance trial (WLM). Design and Methods Secondary analysis of a randomized controlled trial of overweight/obese adults with CVD risk ...
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Journal ArticleObesity (Silver Spring) · January 2014
OBJECTIVE: To determine the effect of age on weight loss and weight loss maintenance in participants in the Weight Loss Maintenance trial (WLM). DESIGN AND METHODS: Secondary analysis of a randomized controlled trial of overweight/obese adults with CVD ris ...
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Journal ArticleJ Am Med Inform Assoc · December 2013
OBJECTIVE: This study compares the yield and characteristics of diabetes cohorts identified using heterogeneous phenotype definitions. MATERIALS AND METHODS: Inclusion criteria from seven diabetes phenotype definitions were translated into query algorithms ...
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Journal ArticleOMICS · December 2013
In overweight/obese individuals, cardiometabolic risk factors differ by race and sex categories. Small-molecule metabolites and metabolic hormone levels might also differ across these categories and contribute to risk factor heterogeneity. To explore this ...
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Journal ArticleAm J Kidney Dis · November 2013
BACKGROUND: Excess adiposity and dietary factors may be important determinants of urinary albumin excretion (UAE). STUDY DESIGN: Observational analysis of PREMIER, a randomized trial designed to lower blood pressure using behavioral interventions (counseli ...
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Journal ArticleJ Acad Nutr Diet · November 2013
BACKGROUND: Efficient dietary interventions for patients with hypertension in clinical settings are needed. OBJECTIVE: To assess the separate and combined influence of a physician intervention (MD-I) and a patient intervention (PT-I) on dietary intakes of ...
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Journal ArticleJAMA Intern Med · October 28, 2013
IMPORTANCE: Few weight loss treatments produce clinically meaningful weight loss outcomes among black women, particularly in the primary care setting. New weight management strategies are necessary for this population. Weight gain prevention might be an ef ...
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Journal ArticleMetabolism · July 2013
OBJECTIVE: To identify novel biomarkers through metabolomic profiles that distinguish metabolically well (MW) from metabolically unwell (MUW) individuals, independent of body mass index (BMI). MATERIALS/METHODS: This study was conducted as part of the Meas ...
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Journal ArticleContemp Clin Trials · July 2013
Obesity has spread to all segments of the U.S. population. Young adults, aged 18-35 years, are rarely represented in clinical weight loss trials. We conducted a qualitative study to identify factors that may facilitate recruitment of young adults into a we ...
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Journal ArticleDiabetologia · June 2013
AIMS/HYPOTHESIS: Clinical trials assessing interventions for treating and preventing diabetes mellitus and its complications are needed to inform evidence-based practice. To examine whether current studies adequately address these needs, we conducted a des ...
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Journal ArticleObesity (Silver Spring) · April 2013
OBJECTIVE: We have previously shown that racial composition of behavioral intervention groups does not affect achieved weight loss. However, it is unclear if the race of the interventionist affects intervention outcomes. The objective of this analysis is t ...
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Journal ArticleAMIA Jt Summits Transl Sci Proc · 2013
Data within a continuing use context (also known as secondary use) can require translation into the variables necessary for project analysis. We have developed and applied a framework in which: Project objectives inform the curation of data elements. Data ...
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Journal ArticleFront Pharmacol · 2013
PURPOSE: Poor adherence to prescribed medicines is associated with increased rates of poor outcomes, including hospitalization, serious adverse events, and death, and is also associated with increased healthcare costs. However, current approaches to evalua ...
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Journal ArticleCan J Nurs Res · December 2012
Inadequate knowledge of the influence of lifestyle on clinical outcomes contributes to the difficulties many African Americans experience with type 2 diabetes mellitus (T2DM). This pilot study examined a 12-week church-based culturally targeted diabetes se ...
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Journal ArticleBreast Cancer Res · October 31, 2012
INTRODUCTION: Changes in sex hormones with weight loss might have implications for breast cancer prevention but have not been examined extensively, particularly in African-American (AA) women. METHODS: We conducted a prospective study of 278 overweight/obe ...
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Journal ArticleObesity (Silver Spring) · September 2012
Effective weight management interventions could reduce race-sex disparities in cardiovascular disease (CVD), yet little is known about factors associated with successful weight loss maintenance in race-sex subgroups. In the Weight Loss Maintenance trial (W ...
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Journal ArticleObesity (Silver Spring) · July 2, 2012
We have previously shown that racial composition of behavioral intervention groups does not affect achieved weight loss. However, it is unclear if the race of the interventionist affects intervention outcomes. The objective of this analysis is to estimate ...
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Journal ArticleBMC Public Health · June 15, 2012
BACKGROUND: Nearly 60% of black women are obese. Despite their increased risk of obesity and associated chronic diseases, black women have been underrepresented in clinical trials of weight loss interventions, particularly those conducted in the primary ca ...
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Journal ArticleDiabetologia · February 2012
AIMS/HYPOTHESIS: Insulin resistance (IR) improves with weight loss, but this response is heterogeneous. We hypothesised that metabolomic profiling would identify biomarkers predicting changes in IR with weight loss. METHODS: Targeted mass spectrometry-base ...
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Chapter · January 1, 2012
Type II diabetes has become one of the most signi cant contributors to morbidity and mortality among the U.S. population. The Centers for Disease Control (CDC) estimated that 23.6 million (7.8%) people in the United States had either diagnosed or undiagnos ...
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Journal ArticleEthn Dis · 2012
OBJECTIVE: To pilot test a culturally adapted behavioral weight loss intervention in obese and overweight Latino adults. DESIGN: Pilot study. SETTING: Latino community organization in Durham, North Carolina. PARTICIPANTS: Overweight and obese, self-identif ...
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Journal ArticleFood Nutr Res · 2012
BACKGROUND: The clinical significance of glycemic index (GI) and glycemic load (GL) is inconclusive. OBJECTIVE: This study was conducted to examine the association of GI and GL with clinical cardiovascular disease (CVD) risk factors including body weight, ...
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Journal Article · December 1, 2011
Insulin continues to be the preferred method for the management of hyperglycemia in the inpatient setting. It can be titrated easily, does not have a ceiling dose, and can be administered intravenously and subcutaneously. Details of IV insulin, including t ...
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Journal Article · December 1, 2011
In 2008, the Centers for Disease Control and Prevention (CDC) estimated that 24 million people in the United States had diabetes mellitus, constituting nearly 8% of the population. The CDC further estimated that 57 million individuals were affected by pred ...
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Journal ArticleJ Am Diet Assoc · December 2011
BACKGROUND: Dietary components effective in weight maintenance efforts have not been adequately identified. OBJECTIVE: To determine the effects of changes in dietary consumption on weight loss and maintenance during the Weight Loss Maintenance clinical tri ...
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Journal ArticleObesity (Silver Spring) · August 2011
Little is known about the transition in behaviors from short-term weight loss to maintenance of weight loss. We wanted to determine how short-term and long-term weight loss and patterns of weight change were associated with intervention behavioral targets. ...
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Journal ArticleJ Gerontol A Biol Sci Med Sci · October 2010
BACKGROUND: To ascertain accuracy of self-reported height, weight (and hence body mass index) in African American and white women and men older than 70 years of age. METHOD: The sample consisted of cognitively intact participants at the third in-person wav ...
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Journal ArticleCirculation · June 8, 2010
BACKGROUND: Increased consumption of sugar-sweetened beverages (SSBs) has been associated with an elevated risk of obesity, metabolic syndrome, and type II diabetes mellitus. However, the effects of SSB consumption on blood pressure (BP) are uncertain. The ...
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Journal ArticleEthn Health · June 2010
OBJECTIVES: To assess the feasibility of a culturally tailored behavioral intervention for improving hypertension-related health behaviors in Hispanic/Latino adults. DESIGN: Feasibility pilot study in a community health center and a Latino organization in ...
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Journal ArticleHypertension · December 2009
Despite widely publicized hypertension treatment guidelines for physicians and lifestyle recommendations for patients, blood pressure control rates remain low. In community-based primary care clinics, we performed a nested, 2 x 2 randomized, controlled tri ...
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Journal ArticleAm J Clin Nutr · May 2009
BACKGROUND: Consumption of liquid calories from beverages has increased in parallel with the obesity epidemic in the US population, but their causal relation remains unclear. OBJECTIVE: The objective of this study was to examine how changes in beverage con ...
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Journal ArticleTrials · February 26, 2009
BACKGROUND: Hypertension affects 29% of the adult U.S. population and is a leading cause of heart disease, stroke, and kidney failure. Despite numerous effective treatments, only 53% of people with hypertension are at goal blood pressure. The chronic care ...
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Journal ArticleJ Clin Hypertens (Greenwich) · August 2008
The authors assessed food availability and cost of the Dietary Approaches to Stop Hypertension (DASH) dietary pattern and patients' opinion concerning diet and blood pressure by surveying grocery stores and clinic patients in low- and high-socioeconomic st ...
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Journal ArticleEndocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · May 1, 2007Cite