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Bryan David Kraft

Adjunct Assistant Professor in the Department of Medicine
Medicine, Pulmonary, Allergy, and Critical Care Medicine
Box 3315 DUMC, Durham, NC 27710

Overview


Dr. Kraft has a wide variety of clinical and research interests, including sepsis, pneumonia, and acute respiratory distress syndrome (ARDS), and has special expertise in rare lung diseases such as pulmonary fibrosis and pulmonary alveolar proteinosis (PAP). PAP can be congenital, hereditary, autoimmune, or due to occupational exposures (e.g. dusts, fibers, silica).

Dr. Kraft performs whole lung lavage (WLL) at Duke in a state-of-the art hyperbaric chamber within the Duke Center for Hyperbaric Medicine and Environmental Physiology. Performing WLL with hyperbaric oxygen (when necessary) augments oxygen delivery during the procedure, meaning both lungs can be lavaged on the same day, during a single episode of anesthesia.

Dr. Kraft’s research laboratory is devoted to understanding mechanisms of acute lung injury resolution, and uses translational models and clinical patient samples to identify novel pathways of recovery. Dr. Kraft is also an active investigator in clinical trials to develop new therapies for patients with lung diseases.

Current Appointments & Affiliations


Adjunct Assistant Professor in the Department of Medicine · 2021 - Present Medicine, Pulmonary, Allergy, and Critical Care Medicine, Medicine

In the News


Published March 13, 2018
Could carbon monoxide be used to manage sepsis-related lung injury? – an interview with Bryan Kraft, MD
Published February 6, 2017
Antibiotics for Sinusitis
Published January 1, 2017
Inhaled CO as a Therapy for ARDS

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Recent Publications


SARS-CoV-2 viremia but not respiratory viral load is associated with respiratory complications in patients with severe COVID-19.

Journal Article BMC Pulm Med · July 29, 2024 BACKGROUND: Severe COVID-19 carries a high morbidity and mortality. Previous studies have shown an association between COVID-19 severity and SARS-CoV-2 viral load (VL). We sought to measure VL in multiple compartments (urine, plasma, lower respiratory trac ... Full text Link to item Cite

Extracorporeal Membrane Oxygenation for Respiratory Failure: A Narrative Review

Journal Article Journal of Clinical Medicine · July 1, 2024 Extracorporeal membrane oxygenation support for respiratory failure in the intensive care unit continues to have an expanded role in select patients. While acute respiratory distress syndrome remains the most common indication, extracorporeal membrane oxyg ... Full text Cite
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Recent Grants


Duke Program of Training in Pulmonary ReSearch to Promote, Engage and Retain Academic Researchers (PROSPER)

Inst. Training Prgm or CMEPreceptor · Awarded by National Heart, Lung, and Blood Institute · 2022 - 2026

METABOLIC SYSTEM FOR IN VIVO RODENT TESTING

EquipmentMentor · Awarded by Office of Naval Research · 2021 - 2022

Role of S-nitrosothiols on Akt1 signaling and pneumonia resolution

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2017 - 2021

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Education, Training & Certifications


University of Tennessee Health Science Center · 2007 M.D.