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Cara L. McDermott

Assistant Professor in Medicine
Medicine, Geriatrics and Palliative Care

Overview


Dr. Cara McDermott is an Assistant Professor in Medicine, Division of Geriatrics, at Duke University School of Medicine. She has a K23 award from NIH's National Heart, Lung and Blood Institute on deprescribing fall-risk increasing drugs among multimorbid adults with chronic obstructive pulmonary disease. Her research focuses on identifying gaps in healthcare delivery and using implementation science to adapt and assess evidence-based interventions. Dr. McDermott works to optimize medication use, improve symptom management, and reduce unwanted healthcare use among older adults with multiple chronic conditions, with a particular interest in improving outcomes for patients with cancer, COPD, or dementia and their caregivers.  She is particularly interested in improving shared decision making in this population and medication deprescribing for adults with serious illness. In recent projects, she investigated ways to improve end-of-life care from the perspective of bereaved caregivers and care delivery gaps leading to unwanted healthcare utilization at end of life for patients with multimorbidity. She completed a T32 postdoctoral fellowship with the Cambia Palliative Care Center of Excellence at the University of Washington and a K12 with the University of Washington’s Implementation Sciences Training Program.

Current Appointments & Affiliations


Assistant Professor in Medicine · 2022 - Present Medicine, Geriatrics and Palliative Care, Medicine
Assistant Professor in Population Health Sciences · 2022 - Present Population Health Sciences, Basic Science Departments
Member of the Duke Cancer Institute · 2025 - Present Duke Cancer Institute, Institutes and Centers

Recent Publications


Psychostimulants for Depression in Serious Illness: Limited Evidence, Select Indications.

Journal Article J Pain Symptom Manage · July 2026 Depression is common in serious illness, yet traditional antidepressants have a delayed onset. Psychostimulants offer potentially rapid symptom relief, but their evidence base for depression, especially in medically complex patients, remains unclear. In th ... Full text Link to item Cite

Drug Burden Index and Its Association With Functional Outcomes in Patients Receiving Hemodialysis.

Journal Article Kidney Med · June 2026 RATIONALE & OBJECTIVE: Psychoactive potentially inappropriate medications (PIMs) are associated with morbidity and mortality in the dialysis population. However, little evidence exists on the association of psychoactive PIMs with functional status, an outc ... Full text Link to item Cite

C35-15 It’s Better to Have Some Medication Than No Medication: Barriers and Facilitators to Deprescribing in Older Adults With Chronic Obstructive Pulmonary Disease

Conference American Journal of Respiratory and Critical Care Medicine · May 1, 2026 AbstractRationalePeople living with chronic obstructive pulmonary disease (COPD) have a high medication burden, which in turn i ... Full text Cite
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Recent Grants


Models of Post-Acute Care in Complex Older Adults with Fracture

ResearchCo Investigator · Awarded by Patient-Centered Outcomes Research Institute · 2024 - 2030

Duke/UNC ADAR Program

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2024 - 2029

Optimizing Medications to Reduce Hospitalizations for Multimorbid Adults with COPD

ResearchPrincipal Investigator · Awarded by Indiana University · 2026 - 2027

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Education


University of Washington · 2016 Ph.D.