Scholars@Duke
Maria Elena Cardenas-Corona

Maria Elena Cardenas-Corona

Research Professor Emeritus of Molecular Genetics and Microbiology
Molecular Genetics and Microbiology
carde004@mc.duke.edu
Duke Box 3054, Durham, NC 27710
321 CARL, 213 Research Dr., Durham, NC 27710

Research Interests

Immunosuppressant, anti-cancer, anti-aging, and anti-fungal drug action mechanisms

Mechanisms of nutrient sensing and control of cell growth by the TORC1 signaling cascade

Dissection of signal transduction pathways

Roles of calcineurin in stress survival and fungal pathogenesis

Protein folding by Prolyl isomerases and their roles in cell growth

Selected Grants

Activation of rapamycin-sensitive TORC1 by endomembrane amino acid transporters

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2011 - 2016

Cancer Biology Training Grant

Inst. Training Prgm or CMEMentor · Awarded by National Cancer Institute · 1993 - 2016

Instrumentation for Quantitative Phosphoproteomics and Acetylomics

EquipmentMajor User · Awarded by National Institutes of Health · 2014 - 2015

Novel Antifungal Therapeutic Approaches

ResearchCo Investigator · Awarded by National Institutes of Health · 2001 - 2014

Signaling mechanisms by the rapamycin target: Tor kinase

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2005 - 2011

Role of Calcineurin in Fungal Virulence

ResearchCollaborator · Awarded by National Institutes of Health · 2004 - 2010

Function of the Rapamycin Targets: The TOR Kinases

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2002 - 2005

Same

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1997 - 2002

Same

ResearchCo Investigator · Awarded by National Institutes of Health · 1997 - 2001

Novel Antifungal Drug Targets In Cryptococcus Neoformans

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 1997 - 1999

Immunosuppressant Targets In Cryptococcus Neoformans

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 1997 - 1999

The Barrier To Xenotransplantation

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 1996 - 1999

The Barrier To Xenotransplantation

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 1993 - 1999