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Carla Wheaton Brady

Professor of Medicine
Medicine, Gastroenterology
Duke Box 3913, Durham, NC 27710
03115 Hosp. South, Durham, NC 27705

Selected Publications


Pragmatic strategies to address health disparities along the continuum of care in chronic liver disease.

Journal Article Hepatol Commun · May 1, 2024 Racial, ethnic, and socioeconomic disparities exist in the prevalence and natural history of chronic liver disease, access to care, and clinical outcomes. Solutions to improve health equity range widely, from digital health tools to policy changes. The cur ... Full text Link to item Cite

Risk of stillbirth in United States patients with diagnosed intrahepatic cholestasis of pregnancy.

Journal Article Am J Obstet Gynecol · October 2023 BACKGROUND: Intrahepatic cholestasis of pregnancy is associated with a 4- to 10-fold increase in the risk of stillbirth in the absence of intervention, leading to recommendations for antenatal assessment, ursodiol use, and often preterm or early term deliv ... Full text Link to item Cite

COVID-19 and the Uncovering of Health Care Disparities in the United States, United Kingdom and Canada: Call to Action.

Journal Article Hepatol Commun · October 2021 The coronavirus disease 2019 (COVID-19) pandemic created a crisis that disproportionately affected populations already disadvantaged with respect to access to health care systems and adequate medical care and treatments. Understanding how and where health ... Full text Link to item Cite

Digestive Disease Week 2020-Tu 1637Longitudinal HCV care of pregnant patients in an "obstetric hepatology clinic"

Conference Gastroenterology · May 5, 2020 Background: Hepatitis C virus (HCV) screening has been recommended in patients born between 1945 and 1965 due to increased HCV incidence. However, HCV infection is occurring at an increased rate in young adults, particularly in young women. As this cohort ... Full text Link to item Cite

Liver Disease in Pregnancy: What's New.

Journal Article Hepatol Commun · February 2020 Liver disease in pregnancy may present as a disorder that is unique to pregnancy or as an acute or chronic liver disease occurring coincidentally in pregnancy. Hepatic diseases that are unique to pregnancy include hyperemesis gravidarum; preeclampsia/eclam ... Full text Link to item Cite

Liver Transplant Outcomes in Menopausal Women During the Meld Era

Conference AMERICAN JOURNAL OF TRANSPLANTATION · 2020 Cite

Identification and Management of Abdominal Wall Varices in Pregnancy.

Journal Article Obstet Gynecol · October 2018 BACKGROUND: Portal hypertension in pregnancy is associated with elevated risk of variceal hemorrhage. Ectopic varices, those located outside the esophagus or stomach, are rare but have a high risk of associated maternal morbidity or mortality. CASE: A 31-y ... Full text Link to item Cite

A FIRST REPORT OF CHOLANGIOCARCINOMA IN GSD I

Conference MOLECULAR GENETICS AND METABOLISM · March 1, 2018 Link to item Cite

A Case of Drug-Induced Liver Injury due to Designer Steroid Use

Conference American Journal of Gastroenterology · October 2017 Full text Cite

Pragmatic strategies to address health disparities along the continuum of care in chronic liver disease.

Journal Article Hepatol Commun · May 1, 2024 Racial, ethnic, and socioeconomic disparities exist in the prevalence and natural history of chronic liver disease, access to care, and clinical outcomes. Solutions to improve health equity range widely, from digital health tools to policy changes. The cur ... Full text Link to item Cite

Risk of stillbirth in United States patients with diagnosed intrahepatic cholestasis of pregnancy.

Journal Article Am J Obstet Gynecol · October 2023 BACKGROUND: Intrahepatic cholestasis of pregnancy is associated with a 4- to 10-fold increase in the risk of stillbirth in the absence of intervention, leading to recommendations for antenatal assessment, ursodiol use, and often preterm or early term deliv ... Full text Link to item Cite

COVID-19 and the Uncovering of Health Care Disparities in the United States, United Kingdom and Canada: Call to Action.

Journal Article Hepatol Commun · October 2021 The coronavirus disease 2019 (COVID-19) pandemic created a crisis that disproportionately affected populations already disadvantaged with respect to access to health care systems and adequate medical care and treatments. Understanding how and where health ... Full text Link to item Cite

Digestive Disease Week 2020-Tu 1637Longitudinal HCV care of pregnant patients in an "obstetric hepatology clinic"

Conference Gastroenterology · May 5, 2020 Background: Hepatitis C virus (HCV) screening has been recommended in patients born between 1945 and 1965 due to increased HCV incidence. However, HCV infection is occurring at an increased rate in young adults, particularly in young women. As this cohort ... Full text Link to item Cite

Liver Disease in Pregnancy: What's New.

Journal Article Hepatol Commun · February 2020 Liver disease in pregnancy may present as a disorder that is unique to pregnancy or as an acute or chronic liver disease occurring coincidentally in pregnancy. Hepatic diseases that are unique to pregnancy include hyperemesis gravidarum; preeclampsia/eclam ... Full text Link to item Cite

Liver Transplant Outcomes in Menopausal Women During the Meld Era

Conference AMERICAN JOURNAL OF TRANSPLANTATION · 2020 Cite

Identification and Management of Abdominal Wall Varices in Pregnancy.

Journal Article Obstet Gynecol · October 2018 BACKGROUND: Portal hypertension in pregnancy is associated with elevated risk of variceal hemorrhage. Ectopic varices, those located outside the esophagus or stomach, are rare but have a high risk of associated maternal morbidity or mortality. CASE: A 31-y ... Full text Link to item Cite

A FIRST REPORT OF CHOLANGIOCARCINOMA IN GSD I

Conference MOLECULAR GENETICS AND METABOLISM · March 1, 2018 Link to item Cite

A Case of Drug-Induced Liver Injury due to Designer Steroid Use

Conference American Journal of Gastroenterology · October 2017 Full text Cite

Liver disease in menopause.

Journal Article World J Gastroenterol · July 7, 2015 There are numerous physiologic and biochemical changes in menopause that can affect the function of the liver and mediate the development of liver disease. Menopause represents a state of growing estrogen deficiency, and this loss of estrogen in the settin ... Full text Link to item Cite

Amiodarone-Induced Liver Injury and Cirrhosis.

Journal Article ACG Case Rep J · January 2015 We present a case report of an 80-year-old woman with volume overload thought initially to be secondary to heart failure, but determined to be amiodarone-induced acute and chronic liver injury leading to submassive necrosis and bridging fibrosis consistent ... Full text Open Access Link to item Cite

Liver disease in pregnancy.

Journal Article World J Gastroenterol · February 28, 2009 Liver diseases in pregnancy may be categorized into liver disorders that occur only in the setting of pregnancy and liver diseases that occur coincidentally with pregnancy. Hyperemesis gravidarum, preeclampsia/eclampsia, syndrome of hemolysis, elevated liv ... Full text Link to item Cite

Disparities in liver transplantation before and after introduction of the MELD score.

Journal Article JAMA · November 26, 2008 CONTEXT: In February 2002, the allocation system for liver transplantation became based on the Model for End-Stage Liver Disease (MELD) score. Before MELD, black patients were more likely to die or become too sick to undergo liver transplantation compared ... Full text Link to item Cite

Frequency and predictors of de novo hepatocellular carcinoma in patients awaiting orthotopic liver transplantation during the model for end-stage liver disease era.

Journal Article Liver Transpl · February 2008 Featured Publication In the current system of allocation, patients awaiting orthotopic liver transplantation (OLT) remain at risk of developing de novo hepatocellular carcinoma (HCC) and removal from the waiting list. Using the United Network for Organ Sharing database, we cal ... Full text Link to item Cite

Factors Influencing Participation in Hepatitis C Research Trials

Conference American Journal of Gastroenterology · September 2007 Full text Cite

The Readability of Hepatitis C Health Education Materials

Conference American Journal of Gastroenterology · September 2007 Full text Cite

Compliance with referral for hepatitis C evaluation among veterans.

Journal Article J Clin Gastroenterol · 2007 Featured Publication GOALS: The goals of this study were to quantify the rate and to identify predictors of compliance with outpatient hepatitis C evaluation. BACKGROUND: Challenges in hepatitis C management include patient compliance with multiple clinic visits, laboratory te ... Full text Link to item Cite

Fibrosis markers in hepatitis C

Journal Article Current Hepatitis Reports · August 1, 2006 Significant morbidity and mortality due to chronic hepatitis C infection have led to efforts to identify patients at risk of progressive disease. Current clinical practice relies on liver biopsy as the gold standard for assessing the severity of chronic he ... Full text Cite

The impact of race and ethnicity on the treatment of hepatitis C disease

Journal Article Current Hepatitis Reports · August 1, 2006 Hepatitis C is the most common blood-borne infection in the United States and the most common cause of liver-related morbidity and mortality. There are significant racial/ethnic disparities in the epidemiology, natural history, and treatment outcomes of he ... Full text Cite