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Nelson Jen An Chao

Donald D. and Elizabeth G. Cooke Cancer Distinguished Research Professor
Medicine, Hematologic Malignancies and Cellular Therapy
DUMC Box 3961, Durham, NC 27710
2400 Pratt St Suite 5000, DUMC Box 3961, Durham, NC 27710

Selected Grants


Improving access to cancer care for children in Tanzania: Designing a health-systems intervention

ResearchCo-Mentor · Awarded by National Institutes of Health · 2022 - 2027

Promoting T cell recovery after radiation injury with long-acting interleukin 7

ResearchCo Investigator · Awarded by National Institutes of Health · 2024 - 2027

Hematology & Transfusion Medicine (T32)

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 1975 - 2026

Centers for Medical Countermeasures against Radiation Consortium

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2005 - 2025

A Randomized Phase 2 Trial to Evaluate Prebiotic Intervention in Allogeneic Hematopoietic Stem Cell Transplantation

ResearchCo Investigator · Awarded by National Institutes of Health · 2020 - 2025

Improving access to cancer care for children in Tanzania: Designing a health-systems intervention

ResearchCo-Mentor · Awarded by National Institutes of Health · 2022 - 2027

Promoting T cell recovery after radiation injury with long-acting interleukin 7

ResearchCo Investigator · Awarded by National Institutes of Health · 2024 - 2027

Hematology & Transfusion Medicine (T32)

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 1975 - 2026

Centers for Medical Countermeasures against Radiation Consortium

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2005 - 2025

A Randomized Phase 2 Trial to Evaluate Prebiotic Intervention in Allogeneic Hematopoietic Stem Cell Transplantation

ResearchCo Investigator · Awarded by National Institutes of Health · 2020 - 2025

Home-based Autologous Hematopoietic Stem Cell Transplantation to Improve Outcomes and Decrease Costs

ResearchCo Investigator · Awarded by National Institutes of Health · 2020 - 2025

RITN 2024 Participation

Public ServicePrincipal Investigator · Awarded by National Marrow Donor Program · 2020 - 2024

Characterization of CMV-specific T cell responses in immunocompromised hosts

ResearchCo-Mentor · Awarded by National Institutes of Health · 2022 - 2024

Viral Oncology Training Grant

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1980 - 2024

Advanced Immunobiology Traning Program for Surgeons

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2019 - 2024

Duke CTSA (TL1) Year 5

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2018 - 2024

Mapping Epigenetic Memory of Exposure New To Observe (MEMENTO)

ResearchInvestigator · Awarded by Defense Advanced Research Projects Agency · 2019 - 2024

Transplant Infectious Diseases Interdisciplinary Research Training Grant (TIDIRTG)

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2018 - 2023

Mechanisms of myeloid cells dysregulation in radiation survivors

ResearchCo Investigator · Awarded by Columbia University · 2022 - 2023

Postdoctoral Training in Genomic Medicine Research

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2017 - 2023

Smartphone Enabled Point-of-Care Detection of Serum Markers of Liver Cancer

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2017 - 2023

Cabinet Radiation Therapy System for Small Animals

EquipmentMajor User · Awarded by North Carolina Biotechnology Center · 2022 - 2023

Home Transplant to Preserve the Microbiota and Decrease GVHD

ResearchMentor · Awarded by American Society of Hematology · 2019 - 2022

U01 RPPR: Mitigators of Radiation-Induced Endovascular Injury: Targeting Tie2 and Thrombocytopenia

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2017 - 2022

Translational Research in Surgical Oncology

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2002 - 2022

T32 UNC - Duke Immunotherapy Training Program

Inst. Training Prgm or CMEPrincipal Investigator · Awarded by University of North Carolina - Chapel Hill · 2021 - 2022

Experimental pharmacology study in mice-Narsoplimab (OMS721)

ResearchPrincipal Investigator · Awarded by Omeros Corporation · 2021 - 2022

Image-Guided Radiation Therapy System for Small Animals

EquipmentMajor User · Awarded by National Institutes of Health · 2021 - 2022

Characterization of CMV-specific T cell responses in immunocompromised hosts

ResearchCo-Mentor · Awarded by National Institutes of Health · 2020 - 2022

Evaluating Effects of Age-related Microbiota Modulations in Hematopoietic Stem Cell Transplant Patients

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2019 - 2022

Patient-centered home-based hematopoietic stem cell transplantation

Clinical TrialPrincipal Investigator · Awarded by National Institutes of Health · 2016 - 2022

Personalized prebiotics to optimize microbiota metabolism and improve transplant outcomes(F)

ResearchPrincipal Investigator · Awarded by American Society of Hematology · 2020 - 2021

Interdisciplinary Training Program in Lung Disease

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2009 - 2021

Targeting Beta-arrestins in myeloid malignancies

ResearchCo-Mentor · Awarded by American Society of Hematology · 2018 - 2020

RITN 2020

Public ServicePrincipal Investigator · Awarded by National Marrow Donor Program · 2019 - 2020

Development of CaMKK2 inhibitor drug for acute radiation syndrome

ResearchPrincipal Investigator · Awarded by Columbia University · 2018 - 2020

AZD9668 and Neutrophil Elastase Inhibition to Prevent Graft-versus-Host Disease

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2018 - 2019

Clinical Validation and Supply of SRI Radiation Biodosimeter

ResearchPrincipal Investigator · Awarded by SRI International · 2018 - 2019

Role of ErbB Receptor Signaling in Regulating Normal and Leukemic Stem Cell Fate

ResearchMentor · Awarded by National Institutes of Health · 2014 - 2019

RITN Opportunity for Radiological Preparedness

Public ServicePrincipal Investigator · Awarded by National Marrow Donor Program · 2018 - 2019

Biodosimetry High-Throughput Test RFP-16-100-SOL-00010

ResearchPrincipal Investigator · Awarded by DxTerity Diagnostics · 2017 - 2019

Duke-UNC Clinical Hematology and Transfusion Research Career Development Program

ResearchMentor · Awarded by National Institutes of Health · 2006 - 2019

3D Biology Signatures defined by Nanostring Max System

EquipmentMajor User · Awarded by North Carolina Biotechnology Center · 2018 - 2019

Dissecting mechanism(s) by which ionizing radiation promotes clonal expansion of premalignant cells in the thymus

ResearchCo-Mentor · Awarded by National Institutes of Health · 2016 - 2018

A novel therap[eutic target for radiation-induced hematological malignancies: calcium calmodulin kinase kinase 2

ResearchPrincipal Investigator · Awarded by Department of Defense · 2015 - 2017

2-O, 3-O desulfated heparin for the prevention of GVHD

ResearchPrincipal Investigator · Awarded by Cantex Pharmaceuticals, Inc. · 2015 - 2017

Point of Care Biodosimeter

ResearchPrincipal Investigator · Awarded by Department of Health and Human Services · 2009 - 2016

Plerixafor for allogeneic hematopoietic stem cell transplantation

ResearchMentor · Awarded by National Institutes of Health · 2014 - 2016

Validation of a microRNA signature for the prediction, diagnosis and prognosis of acute graft-versus-host disease

ResearchCo Investigator · Awarded by Blood and Marrow Transplant Clinical Trials Network · 2015 - 2015

Clinical Oncology Research Career Development Program

ResearchMentor · Awarded by National Institutes of Health · 2009 - 2015

BAFF Pathology: Novel Therapeutic Targets in Chronic Graft versus Host Disease

ResearchMentor · Awarded by National Institutes of Health · 2011 - 2015

Plasma microRNAs as non-invasive biomarker for acute graft-versus-host diseases

ResearchInvestigator · Awarded by The Biomarker Factory · 2014 - 2015

RITN Agreement

Public ServicePrincipal Investigator · Awarded by National Marrow Donor Program · 2006 - 2014

Novel Approaches to Stem Cell Transplantation

Clinical TrialPrincipal Investigator · Awarded by National Institutes of Health · 2009 - 2014

Endothelial Progenitor Cell Transplant to Accelerate Hematopoietic Recovery

ResearchConsultant · Awarded by National Institutes of Health · 2008 - 2013

Skin Stem Cells in Combined Radiation Injury

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2008 - 2013

Graft Engineering and Immunotherapy After Unrelated Cord Blood Transplantation

ResearchSignificant Contributor · Awarded by National Institutes of Health · 2007 - 2011

Innate Immune Response to Environmental Endotoxin

ResearchConsultant · Awarded by National Institutes of Health · 2004 - 2009

Non-Myeloablative Cord Blood Transplantation

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1999 - 2008

Dendritic Cell Based Vaccination for Multiple Myeloma

ResearchSponsor · Awarded by National Institutes of Health · 2002 - 2007

Cord Blood Transplantation

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2002 - 2007

Bone Marrow Transplantation for Breast Cancer

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1990 - 2003

Comprehensive Cancer Center Core Support Grant

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 1976 - 1998

Cancer Center Core Support Grant

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 1976 - 1998