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Chenyu Lin

Assistant Professor of Medicine
Medicine, Hematologic Malignancies and Cellular Therapy
2400 Pratt Street, Suite 5000, Durham, NC 27705
2400 Pratt Street, Suite 5000, Durham, NC 27705

Overview


Medical Director, Cellular Therapy Program

Hematologic oncologist specializing in the care of patients with acute leukemias and aggressive lymphomas, and those patients who require administration of an immune effector cellular therapy. Dr. Lin oversees Duke's cellular therapy program, which provides cell-based treatments such as chimeric antigen receptor T (CAR T) cell therapy, engineered T cell receptor (TCR) therapy, and tumor infiltrating lymphocytes (TILs) for a variety of cancers and autoimmune disorders. His research interests include clinical trials, digital health, and real-world evidence.

Fellowship: Duke Cancer Institute
Residency: Northwestern University
Medical School: University of Chicago Pritzker School of Medicine
Undergraduate: Yale University

Current Duke Appointments & Affiliations


Assistant Professor of Medicine · 2023 - Present Medicine, Hematologic Malignancies and Cellular Therapy, Medicine
Member of the Duke Cancer Institute · 2023 - Present Duke Cancer Institute, Institutes and Centers

Recent News Items


Published October 2, 2024
Pharmacy Times
Decitabine Demonstrates Therapeutic Potential for the Treatment of Myelofibrosis
Published August 5, 2024
U.S. Medicine
KRAS G12C in Veterans with NSCLC Has Favorable Outcomes Compared to Non-G12C Variants; Availability of Sotorasib Treatment Credited
Published May 29, 2023
U.S. Medicine
VA Demonstrates Success in Remote Treatment of Aggressive Cancers

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Recent Scholarly Works


Hybrid-delivered cognitive behavioral symptom management and activity coaching intervention for patients following hematopoietic stem cell transplant or CAR T-cell therapy: Protocol of a randomized controlled trial.

Journal article Contemp Clin Trials · July 2026 BACKGROUND: Patients undergoing hematopoietic stem cell transplant (HCT) and chimeric antigen receptor T-cell (CAR-T) therapy experience significant disability exacerbated by persistent fatigue, pain, and psychological distress. These symptoms limit physic ... Full text Link to item Cite

Allogeneic Hematopoietic Cell Transplant Following Standard of Care Brexucabtagene Autoleucel (Brexu-cel) in Adults with B-Cell Acute Lymphoblastic Leukemia (B-ALL): Results from the Real-World Outcomes Collaborative of CAR T in Adult ALL (ROCCA).

Journal article Transplant Cell Ther · June 27, 2026 INTRODUCTION: Brexucabtagene autoleucel (brexu-cel) is an autologous anti-CD19 chimeric antigen receptor T (CAR T) cell therapy approved for adults with relapsed/refractory (r/r) B-ALL. Despite encouraging outcomes, the majority of adults relapse following ... Full text Link to item Cite

Improved Outcomes with TKI Maintenance Following Brexucabtagene Autoleucel in Philadelphia-chromosome ALL.

Journal article Blood Adv · June 25, 2026 Brexucabtagene-autoleucel (brexu-cel) produces high rates of measurable residual disease-negative (MRD-) complete response (CR) in adults with Philadelphia-chromosome positive (Ph+) acute lymphoblastic leukemia (ALL); however, subsequent relapses remain fr ... Full text Link to item Cite
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Education


The University of Chicago · 2016 M.D.

External Links


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