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Chiara Melloni

Adjunct Associate Professor in the Department of Medicine
Medicine, Cardiology
Duke Box 3850, Durham, NC 27710
2400 Pratt St, Durham, NC 27710

Current Appointments & Affiliations


Adjunct Associate Professor in the Department of Medicine · 2020 - Present Medicine, Cardiology, Medicine

Recent Publications


Medicare coverage gap status, adherence to oral anticoagulation, and stroke rates in patients with atrial fibrillation.

Journal Article Am Heart J · January 2026 BACKGROUND: Prior to 2025, Medicare Part D included a coverage gap during which beneficiaries were responsible for substantially higher portions of medication costs. The impact of this on oral anticoagulant (OAC) prescription fills and subsequent stroke in ... Full text Link to item Cite

Aficamten Treatment for Symptomatic Obstructive Hypertrophic Cardiomyopathy: 48-Week Results From FOREST-HCM.

Journal Article JACC Heart Fail · August 2025 BACKGROUND: Long-term safety and efficacy data for aficamten in symptomatic obstructive hypertrophic cardiomyopathy are needed. OBJECTIVES: This study aims to evaluate 48-week experience from the ongoing FOREST-HCM (A Follow-Up, Open-Label, Research Evalua ... Full text Link to item Cite

Concomitant Aficamten and Disopyramide in Symptomatic Obstructive Hypertrophic Cardiomyopathy.

Journal Article JACC Heart Fail · April 2, 2025 BACKGROUND: Disopyramide, used in obstructive hypertrophic cardiomyopathy (oHCM) for its negative inotropic properties mediated by its reduction in cytosolic calcium, has been recommended for decades as an option to relieve resistant obstruction. Aficamten ... Full text Link to item Cite
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Recent Grants


PTN2- TO# BPCA Pharmacology Studies

ResearchPanel Member · Awarded by National Institute for Child Health & Human Develo · 2018 - 2023

PTN_TO#50 POPS LAB

Clinical TrialPrincipal Investigator · Awarded by National Institutes of Health · 2017 - 2022

Heart Failure Network: Year 12 Non-Compete Renewal

Clinical TrialMedical Monitor · Awarded by National Institutes of Health · 2006 - 2021

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Education, Training & Certifications


University of Bologna (Italy) · 1999 M.D.