Current Appointments & Affiliations
Adjunct Associate Professor in the Department of Medicine
·
2020 - Present
Medicine, Cardiology,
Medicine
Recent Publications
Standard-of-Care Medication Withdrawal in Patients With Obstructive Hypertrophic Cardiomyopathy Receiving Aficamten in FOREST-HCM.
Journal Article J Am Coll Cardiol · November 5, 2024 BACKGROUND: Standard-of-care (SoC) medications for the treatment of obstructive hypertrophic cardiomyopathy (oHCM) are recommended as first-line therapy despite the lack of evidence from controlled clinical trials and well known off-target side effects. OB ... Full text Link to item CiteSafety and efficacy of aficamten in patients with non-obstructive hypertrophic cardiomyopathy: A 36-week analysis from FOREST-HCM.
Journal Article Eur J Heart Fail · September 2024 AIMS: The aim of this study was to report safety and efficacy of aficamten in patients with non-obstructive hypertrophic cardiomyopathy (nHCM) over 36 weeks in the ongoing FOREST-HCM trial. METHODS AND RESULTS: Patients were started on aficamten 5 mg daily ... Full text Link to item CiteUse of physiologically-based pharmacokinetic modeling to inform dosing of the opioid analgesics fentanyl and methadone in children with obesity.
Journal Article CPT Pharmacometrics Syst Pharmacol · June 2022 Obesity is an increasingly alarming public health threat, with nearly 20% of children classified as obese in the United States today. Children with obesity are commonly prescribed the opioids fentanyl and methadone, and accurate dosing is critical to reduc ... Full text Link to item CiteRecent Grants
PTN2- TO# BPCA Pharmacology Studies
ResearchPanel Member · Awarded by National Institute for Child Health & Human Develo · 2018 - 2023PTN_TO#50 POPS LAB
Clinical TrialPrincipal Investigator · Awarded by National Institutes of Health · 2017 - 2022Heart Failure Network: Year 12 Non-Compete Renewal
Clinical TrialMedical Monitor · Awarded by National Institutes of Health · 2006 - 2021View All Grants
Education, Training & Certifications
University of Bologna (Italy) ·
1999
M.D.