Overview
2. Global Health
3. Epidemiology of infectious diseases
4. Clinical microbiology and diagnostics
5. Bioterrorism Preparedness
6. Surveillance for communicable diseases
7. Antimicrobial resistance
Current Appointments & Affiliations
Wolfgang Joklik Distinguished Professor of Global Health
·
2023 - Present
Medicine, Infectious Diseases,
Medicine
Professor of Medicine
·
2014 - Present
Medicine, Infectious Diseases,
Medicine
Associate Director of Duke Center for Applied Genomics and Precision Medicine
·
2014 - Present
The Precision Medicine Program,
Medicine
Research Professor of Global Health
·
2011 - Present
Duke Global Health Institute,
University Institutes and Centers
Professor in Pathology
·
2014 - Present
Pathology,
Clinical Science Departments
Member of the Duke Human Vaccine Institute
·
2023 - Present
Duke Human Vaccine Institute,
Institutes and Centers
Recent Publications
Age-associated differences in mucosal and systemic host responses to SARS-CoV-2 infection.
Journal Article Nat Commun · March 10, 2025 Age is among the strongest risk factors for severe outcomes from SARS-CoV-2 infection. Here we describe upper respiratory tract (URT) and peripheral blood transcriptomes of 202 participants (age range of 1 week to 83 years), including 137 non-hospitalized ... Full text Link to item CiteComprehensive guide for epigenetics and transcriptomics data quality control.
Journal Article STAR Protoc · January 26, 2025 Host response to environmental exposures such as pathogens and chemicals can include modifications to the epigenome and transcriptome. Improved signature discovery, including the identification of the agent and timing of exposure, has been enabled by advan ... Full text Link to item CiteA Rapid Host Response Blood Test for Bacterial/Viral Infection Discrimination Using a Portable Molecular Diagnostic Platform.
Journal Article Open Forum Infect Dis · January 2025 BACKGROUND: Difficulty discriminating bacterial versus viral etiologies of infection drives unwarranted antibacterial prescriptions and, therefore, antibacterial resistance. METHODS: Utilizing a rapid portable test that measures peripheral blood host gene ... Full text Link to item CiteRecent Grants
Multiscale Modeling of Influenza Neutralizing Antibody and Fc Effector Biology
ResearchInvestigator · Awarded by National Institute of Allergy and Infectious Diseases · 2024 - 2029Stimulating Access to Research in Residency (StARR) - NIAID
Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2018 - 2029Identification of Host-Specific Determinants of APOL1-associated COVAN
ResearchCo-Mentor · Awarded by National Institute of Diabetes and Digestive and Kidney Diseases · 2024 - 2029View All Grants
Education, Training & Certifications
Duke University ·
1994
M.D.