Christina D Williams | Scholars@Duke

Christina D Williams
Assistant Professor in Medicine

Current Appointments & Affiliations

Assistant Professor in Medicine, Medicine, Medical Oncology, Medicine 2021
Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 2013

Contact Information

VA Med Ctr Bldg 16 Rm 57 508 F, Box 3445, Durham, NC 27705
christina.williams@duke.edu (919) 286-6936

Background
Education, Training, & Certifications
- Ph.D., University of North Carolina - Chapel Hill 2009
Previous Appointments & Affiliations
- Assistant Professor in Medicine, Medicine, Medical Oncology, Medicine 2013 - 2020
Recognition
In the News
- NOV 3, 2021 Nasher Museum of Art
  
  The Nasher Art Minute: Prelude to a Calamity
Research
Selected Grants
- IPA - Teresa C Day awarded by Durham Veterans Affairs Medical Center 2021 - 2022
- EGFR Testing Patterns and Outcomes in Non-Small Cell Lung Cancer in the VA Health System awarded by AstraZeneca Pharmaceuticals, LP 2018 - 2020
- Stage III NSCLC in the VA Health System awarded by AstraZeneca Pharmaceuticals, LP 2018 - 2020
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Sullivan, Brian A., Thomas S. Redding, Xuejun Qin, Ziad F. Gellad, Elizabeth R. Hauser, Meghan C. O’Leary, Christina D. Williams, et al. “Ten or More Cumulative Lifetime Adenomas Are Associated with Increased Risk for Advanced Neoplasia and Colorectal Cancer.” Dig Dis Sci 67, no. 6 (June 2022): 2526–34. https://doi.org/10.1007/s10620-021-07069-0.
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  - Gifford, Elizabeth J., Stephen H. Boyle, Jacqueline Vahey, Kellie J. Sims, Jimmy T. Efird, Blair Chesnut, Crystal Stafford, et al. “Health-Related Quality of Life by Gulf War Illness Case Status.” Int J Environ Res Public Health 19, no. 8 (April 7, 2022). https://doi.org/10.3390/ijerph19084425.
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  - Sullivan, Brian A., Xuejun Qin, Cameron Miller, Elizabeth R. Hauser, Thomas S. Redding, Ziad F. Gellad, Ashton N. Madison, et al. “Screening Colonoscopy Findings Are Associated With Noncolorectal Cancer Mortality.” Clin Transl Gastroenterol 13, no. 4 (April 1, 2022): e00479. https://doi.org/10.14309/ctg.0000000000000479.
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  - Efird, Jimmy T., Ethan J. Anderson, Charulata Jindal, Thomas S. Redding, Andrew D. Thompson, Ashlyn M. Press, Julie Upchurch, Christina D. Williams, Yuk Ming Choi, and Ayako Suzuki. “The Interaction of Vitamin D and Corticosteroids: A Mortality Analysis of 26,508 Veterans Who Tested Positive for SARS-CoV-2.” Int J Environ Res Public Health 19, no. 1 (December 31, 2021). https://doi.org/10.3390/ijerph19010447.
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  - Vahey, Jacqueline, Elizabeth J. Gifford, Kellie J. Sims, Blair Chesnut, Stephen H. Boyle, Crystal Stafford, Julie Upchurch, et al. “Gene-Toxicant Interactions in Gulf War Illness: Differential Effects of the PON1 Genotype.” Brain Sci 11, no. 12 (November 25, 2021). https://doi.org/10.3390/brainsci11121558.
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  - Suzuki, Ayako, Jimmy T. Efird, Thomas S. Redding, Andrew D. Thompson, Ashlyn M. Press, Christina D. Williams, Christopher J. Hostler, and Christine M. Hunt. “COVID-19-Associated Mortality in US Veterans with and without SARS-CoV-2 Infection.” Int J Environ Res Public Health 18, no. 16 (August 11, 2021). https://doi.org/10.3390/ijerph18168486.
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  - Sayani, Ambreen, Muhanad Ahmed Ali, Ann Marie Corrado, Carolyn Ziegler, Alex Sadler, Christina Williams, and Aisha Lofters. “Interventions designed to increase the uptake of lung cancer screening and implications for priority populations: a scoping review protocol.” Bmj Open 11, no. 7 (July 28, 2021): e050056. https://doi.org/10.1136/bmjopen-2021-050056.
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  - Wilkie, Joel R., Rachel Lipson, Matthew C. Johnson, Christina Williams, Drew Moghanaki, David Elliott, Dawn Owen, Namratha Atluri, Shruti Jolly, and Christina Hunter Chapman. “Use and Outcomes of SBRT for Early Stage NSCLC Without Pathologic Confirmation in the Veterans Health Care Administration.” Adv Radiat Oncol 6, no. 4 (July 2021): 100707. https://doi.org/10.1016/j.adro.2021.100707.
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  - Hong, Julian C., Elizabeth R. Hauser, Thomas S. Redding, Kellie J. Sims, Ziad F. Gellad, Meghan C. O’Leary, Terry Hyslop, et al. “Characterizing chronological accumulation of comorbidities in healthy veterans: a computational approach.” Sci Rep 11, no. 1 (April 14, 2021): 8104. https://doi.org/10.1038/s41598-021-85546-2.
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  - O’Leary, Meghan C., R Lawrence Whitley, Ashlyn Press, Dawn Provenzale, Christina D. Williams, Blair Chesnut, Rodney Jones, Thomas S. Redding, and Kellie J. Sims. “Development of a Multi-Study Repository to Support Research on Veteran Health: The VA Cooperative Studies Program Epidemiology Center-Durham (CSPEC-Durham) Data and Specimen Repository.” Front Public Health 9 (2021): 612806. https://doi.org/10.3389/fpubh.2021.612806.
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  - Sullivan, Brian A., Thomas S. Redding, Elizabeth R. Hauser, Ziad F. Gellad, Xuejun Qin, Samir Gupta, Douglas J. Robertson, et al. “High-Risk Adenomas at Screening Colonoscopy Remain Predictive of Future High-Risk Adenomas Despite an Intervening Negative Colonoscopy.” Am J Gastroenterol 115, no. 8 (August 2020): 1275–82. https://doi.org/10.14309/ajg.0000000000000677.
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  - Low, Eric E., Joshua Demb, Lin Liu, Ashley Earles, Ranier Bustamante, Christina D. Williams, Dawn Provenzale, et al. “Risk Factors for Early-Onset Colorectal Cancer.” Gastroenterology 159, no. 2 (August 2020): 492-501.e7. https://doi.org/10.1053/j.gastro.2020.01.004.
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  - Lieberman, David, Brian A. Sullivan, Elizabeth R. Hauser, Xuejun Qin, Laura W. Musselwhite, Meghan C. O’Leary, Thomas S. Redding, et al. “Baseline Colonoscopy Findings Associated With 10-Year Outcomes in a Screening Cohort Undergoing Colonoscopy Surveillance.” Gastroenterology 158, no. 4 (March 2020): 862-874.e8. https://doi.org/10.1053/j.gastro.2019.07.052.
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  - Spiegel, Daphna Y., Matthew J. Boyer, Julian C. Hong, Christina D. Williams, Michael J. Kelley, Joseph K. Salama, and Manisha Palta. “Survival Advantage With Adjuvant Chemotherapy for Locoregionally Advanced Rectal Cancer: A Veterans Health Administration Analysis.” J Natl Compr Canc Netw 18, no. 1 (January 2020): 52–58. https://doi.org/10.6004/jnccn.2019.7329.
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  - Williams, Christina D., Naomi Alpert, Thomas S. Redding, A Jasmine Bullard, Raja M. Flores, Michael J. Kelley, and Emanuela Taioli. “Racial Differences in Treatment and Survival among Veterans and Non-Veterans with Stage I NSCLC: An Evaluation of Veterans Affairs and SEER-Medicare Populations.” Cancer Epidemiol Biomarkers Prev 29, no. 1 (January 2020): 112–18. https://doi.org/10.1158/1055-9965.EPI-19-0245.
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  - Brown, Mackenzie C., Kellie J. Sims, Elizabeth J. Gifford, Karen M. Goldstein, Marcus R. Johnson, Christina D. Williams, and Dawn Provenzale. “Gender-based Differences among 1990-1991 Gulf War Era Veterans: Demographics, Lifestyle Behaviors, and Health Conditions.” Womens Health Issues 29 Suppl 1 (June 25, 2019): S47–55. https://doi.org/10.1016/j.whi.2019.04.004.
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  - Williams, Christina D., Alyssa Jasmine Bullard, Meghan O’Leary, Reana Thomas, Thomas S. Redding, and Karen Goldstein. “Racial/Ethnic Disparities in BRCA Counseling and Testing: a Narrative Review.” J Racial Ethn Health Disparities 6, no. 3 (June 2019): 570–83. https://doi.org/10.1007/s40615-018-00556-7.
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  - Spiegel, Daphna Y., Matthew J. Boyer, Julian C. Hong, Christina D. Williams, Michael J. Kelley, Harvey Moore, Joseph K. Salama, and Manisha Palta. “Long-term Clinical Outcomes of Nonoperative Management With Chemoradiotherapy for Locally Advanced Rectal Cancer in the Veterans Health Administration.” Int J Radiat Oncol Biol Phys 103, no. 3 (March 1, 2019): 565–73. https://doi.org/10.1016/j.ijrobp.2018.10.018.
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  - Hong, Julian C., Matthew J. Boyer, Daphna Y. Spiegel, Christina D. Williams, Betty C. Tong, Scott L. Shofer, Michael J. Moravan, Michael J. Kelley, and Joseph K. Salama. “Increasing PET Use in Small Cell Lung Cancer: Survival Improvement and Stage Migration in the VA Central Cancer Registry.” J Natl Compr Canc Netw 17, no. 2 (February 2019): 127–39. https://doi.org/10.6004/jnccn.2018.7090.
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  - Zullig, Leah L., Karen M. Goldstein, Kellie J. Sims, Christina D. Williams, Michael Chang, Dawn Provenzale, and Michael J. Kelley. “Cancer Among Women Treated in the Veterans Affairs Healthcare System.” J Womens Health (Larchmt) 28, no. 2 (February 2019): 268–75. https://doi.org/10.1089/jwh.2018.6936.
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  - Zullig, Leah L., Valerie A. Smith, Jennifer H. Lindquist, Christina D. Williams, Morris Weinberger, Dawn Provenzale, George L. Jackson, Michael J. Kelley, Susanne Danus, and Hayden B. Bosworth. “Cardiovascular disease-related chronic conditions among Veterans Affairs nonmetastatic colorectal cancer survivors: a matched case-control analysis.” Cancer Manag Res 11 (2019): 6793–6802. https://doi.org/10.2147/CMAR.S191040.
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  - Earles, Ashley, Lin Liu, Ranier Bustamante, Pat Coke, Julie Lynch, Karen Messer, María Elena Martínez, et al. “Structured Approach for Evaluating Strategies for Cancer Ascertainment Using Large-Scale Electronic Health Record Data.” Jco Clin Cancer Inform 2 (December 2018): 1–12. https://doi.org/10.1200/CCI.17.00072.
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  - Boyer, Matthew J., Christina D. Williams, David H. Harpole, Mark W. Onaitis, Michael J. Kelley, and Joseph K. Salama. “Improved Survival of Stage I Non-Small Cell Lung Cancer: A VA Central Cancer Registry Analysis.” J Thorac Oncol 12, no. 12 (December 2017): 1814–23. https://doi.org/10.1016/j.jtho.2017.09.1952.
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  - Zullig, Leah L., Kellie J. Sims, Rebecca McNeil, Christina D. Williams, George L. Jackson, Dawn Provenzale, and Michael J. Kelley. “Cancer Incidence Among Patients of the U.S. Veterans Affairs Health Care System: 2010 Update.” Mil Med 182, no. 7 (July 2017): e1883–91. https://doi.org/10.7205/MILMED-D-16-00371.
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  - Paulus, Jessica K., Christina D. Williams, Furha I. Cossor, Michael J. Kelley, and Robert E. Martell. “Metformin, Diabetes, and Survival among U.S. Veterans with Colorectal Cancer-Response.” Cancer Epidemiol Biomarkers Prev 26, no. 6 (June 2017): 977. https://doi.org/10.1158/1055-9965.EPI-16-1026.
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  - Zullig, Leah L., William R. Carpenter, and Christina D. Williams. “Next steps to improve disparities in lung cancer treatment clinical trial enrollment.” Ann Transl Med 5, no. 5 (March 2017): 118. https://doi.org/10.21037/atm.2017.01.25.
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  - Williams, Christina D., William M. Grady, and Leah L. Zullig. “Use of NCCN Guidelines, Other Guidelines, and Biomarkers for Colorectal Cancer Screening.” J Natl Compr Canc Netw 14, no. 11 (November 2016): 1479–85. https://doi.org/10.6004/jnccn.2016.0154.
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  - Paulus, Jessica K., Christina D. Williams, Furha I. Cossor, Michael J. Kelley, and Robert E. Martell. “Metformin, Diabetes, and Survival among U.S. Veterans with Colorectal Cancer.” Cancer Epidemiol Biomarkers Prev 25, no. 10 (October 2016): 1418–25. https://doi.org/10.1158/1055-9965.EPI-16-0312.
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  - Williams, Christina D., Joseph K. Salama, Drew Moghanaki, Tomer Z. Karas, and Michael J. Kelley. “Impact of Race on Treatment and Survival among U.S. Veterans with Early-Stage Lung Cancer.” J Thorac Oncol 11, no. 10 (October 2016): 1672–81. https://doi.org/10.1016/j.jtho.2016.05.030.
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  - Ganti, Apar Kishor, Christina D. Williams, Ajeet Gajra, and Michael J. Kelley. “Effect of age on the efficacy of adjuvant chemotherapy for resected non-small cell lung cancer.” Cancer 121, no. 15 (August 1, 2015): 2578–85. https://doi.org/10.1002/cncr.29360.
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  - Vidal, Adriana C., Christina D. Williams, Emma H. Allott, Lauren E. Howard, Delores J. Grant, Megan McPhail, Katharine N. Sourbeer, et al. “Carbohydrate intake, glycemic index and prostate cancer risk.” Prostate 75, no. 4 (March 1, 2015): 430–39. https://doi.org/10.1002/pros.22929.
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  - Santana-Davila, Rafael, Kiran Devisetty, Aniko Szabo, Rodney Sparapani, Carlos Arce-Lara, Elizabeth M. Gore, Amy Moran, Christina D. Williams, Michael J. Kelley, and Jeffrey Whittle. “Cisplatin and etoposide versus carboplatin and paclitaxel with concurrent radiotherapy for stage III non-small-cell lung cancer: an analysis of Veterans Health Administration data.” J Clin Oncol 33, no. 6 (February 20, 2015): 567–74. https://doi.org/10.1200/JCO.2014.56.2587.
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  - Zullig, Leah L., Christina D. Williams, and Alice G. Fortune-Britt. “Lung and colorectal cancer treatment and outcomes in the Veterans Affairs health care system.” Cancer Manag Res 7 (2015): 19–35. https://doi.org/10.2147/CMAR.S75463.
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  - Samuel, Cleo A., Mary Beth Landrum, Barbara J. McNeil, Samuel R. Bozeman, Christina D. Williams, and Nancy L. Keating. “Racial disparities in cancer care in the Veterans Affairs health care system and the role of site of care.” Am J Public Health 104 Suppl 4 (September 2014): S562–71. https://doi.org/10.2105/AJPH.2014.302079.
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  - Williams, Christina D., Ajeet Gajra, Apar K. Ganti, and Michael J. Kelley. “Use and impact of adjuvant chemotherapy in patients with resected non-small cell lung cancer.” Cancer 120, no. 13 (July 1, 2014): 1939–47. https://doi.org/10.1002/cncr.28679.
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  - Santana-Davila, Rafael, Aniko Szabo, Carlos Arce-Lara, Christina D. Williams, Michael J. Kelley, and Jeff Whittle. “Cisplatin versus carboplatin-based regimens for the treatment of patients with metastatic lung cancer. An analysis of Veterans Health Administration data.” J Thorac Oncol 9, no. 5 (May 2014): 702–9. https://doi.org/10.1097/JTO.0000000000000146.
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  - Nipp, Ryan D., Michael J. Kelley, Christina D. Williams, and Arif H. Kamal. “Evolution of the Quality Oncology Practice Initiative supportive care quality measures portfolio and conformance at a Veterans Affairs medical center.” J Oncol Pract 9, no. 3 (May 2013): e86–89. https://doi.org/10.1200/JOP.2013.000923.
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  - Williams, Christina D. “Antioxidants and prevention of gastrointestinal cancers.” Curr Opin Gastroenterol 29, no. 2 (March 2013): 195–200. https://doi.org/10.1097/MOG.0b013e32835c9d1b.
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  - Williams, Christina D., Karen M. Stechuchak, Leah L. Zullig, Dawn Provenzale, and Michael J. Kelley. “Influence of comorbidity on racial differences in receipt of surgery among US veterans with early-stage non-small-cell lung cancer.” J Clin Oncol 31, no. 4 (February 1, 2013): 475–81. https://doi.org/10.1200/JCO.2012.44.1170.
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  - Zullig, Leah L., William R. Carpenter, Dawn T. Provenzale, Morris Weinberger, Bryce B. Reeve, Christina D. Williams, and George L. Jackson. “The association of race with timeliness of care and survival among Veterans Affairs health care system patients with late-stage non-small cell lung cancer.” Cancer Manag Res 5 (2013): 157–63. https://doi.org/10.2147/CMAR.S46688.
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  - Vidal, Adriana C., Delores J. Grant, Christina D. Williams, Elizabeth Masko, Emma H. Allott, Kathryn Shuler, Megan McPhail, et al. “Associations between Intake of Folate, Methionine, and Vitamins B-12, B-6 and Prostate Cancer Risk in American Veterans.” J Cancer Epidemiol 2012 (2012): 957467. https://doi.org/10.1155/2012/957467.
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  - Williams, Christina D., Brian M. Whitley, Cathrine Hoyo, Delores J. Grant, Gary G. Schwartz, Joseph C. Presti, Jared D. Iraggi, et al. “Dietary calcium and risk for prostate cancer: a case-control study among US veterans.” Prev Chronic Dis 9 (2012): E39. https://doi.org/10.5888/pcd9.110125.
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  - Williams, Christina D., Brian M. Whitley, Cathrine Hoyo, Delores J. Grant, Jared D. Iraggi, Kathryn A. Newman, Leah Gerber, Loretta A. Taylor, Madeline G. McKeever, and Stephen J. Freedland. “A high ratio of dietary n-6/n-3 polyunsaturated fatty acids is associated with increased risk of prostate cancer.” Nutr Res 31, no. 1 (January 2011): 1–8. https://doi.org/10.1016/j.nutres.2011.01.002.
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  - Williams, Christina Dawn, Jessie A. Satia, Linda S. Adair, June Stevens, Joseph Galanko, Temitope O. Keku, and Robert S. Sandler. “Antioxidant and DNA methylation-related nutrients and risk of distal colorectal cancer.” Cancer Causes Control 21, no. 8 (August 2010): 1171–81. https://doi.org/10.1007/s10552-010-9544-3.
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  - Freedland, Stephen J., Christina D. Williams, and Elizabeth M. Masko. “Adiponectin and prostate cancer mortality: to be or not to be skinny?” Clin Chem 56, no. 1 (January 2010): 1–3. https://doi.org/10.1373/clinchem.2009.137406.
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  - Williams, Christina Dawn, Jessie A. Satia, Linda S. Adair, June Stevens, Joseph Galanko, Temitope O. Keku, and Robert S. Sandler. “Associations of red meat, fat, and protein intake with distal colorectal cancer risk.” Nutr Cancer 62, no. 6 (2010): 701–9. https://doi.org/10.1080/01635581003605938.
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  - Williams, Christina Dawn, Jessie A. Satia, Linda S. Adair, June Stevens, Joseph Galanko, Temitope O. Keku, and Robert S. Sandler. “Dietary patterns, food groups, and rectal cancer risk in Whites and African-Americans.” Cancer Epidemiol Biomarkers Prev 18, no. 5 (May 2009): 1552–61. https://doi.org/10.1158/1055-9965.EPI-08-1146.
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  - Schmidt, Silke, Kelli D. Allen, Valerie T. Loiacono, Barbara Norman, Catherine L. Stanwyck, Kristina M. Nord, Christina D. Williams, et al. “Genes and Environmental Exposures in Veterans with Amyotrophic Lateral Sclerosis: the GENEVA study. Rationale, study design and demographic characteristics.” Neuroepidemiology 30, no. 3 (2008): 191–204. https://doi.org/10.1159/000126911.
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- Book Sections
  - Zullig, L. L., C. D. Williams, and H. J. Cohen. “Aging.” In Handbook of Cancer Survivorship: Second Edition, 91–109, 2018. https://doi.org/10.1007/978-3-319-77432-9_6.
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- Conference Papers
  - Sullivan, Brian A., Xuejun Qin, Thomas S. Redding, Ziad F. Gellad, Anjanette Stone, David Weiss, Ashton N. Madison, et al. “Genetic Colorectal Cancer and Adenoma Risk Variants Are Associated with Increasing Cumulative Adenoma Counts.” In Cancer Epidemiol Biomarkers Prev, 29:2269–76, 2020. https://doi.org/10.1158/1055-9965.EPI-20-0465.
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Education, Training, & Certifications

Previous Appointments & Affiliations

In the News

Selected Grants

Selected Publications

Academic Articles

Book Sections

Conference Papers