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Christopher Stephen Boehlke

Assistant Professor of Ophthalmology
Ophthalmology, Corneal Diseases
2351 Erwin Road - Duke Eye Cen, BOX_3802, Durham, NC 27710

Selected Publications

Corneal neurotization

Chapter · January 31, 2022 Corneal neurotization is an exciting and powerful means of improving vision in patients with neurotrophic keratitis, although much remains to be clarified about the procedure. The evolution of the procedure and its results are discussed herein. ... Full text Cite

Clinical and Morphologic Outcomes of Minimally Invasive Direct Corneal Neurotization.

Journal Article Ophthalmic Plast Reconstr Surg · 2020 PURPOSE: To describe clinical outcomes of a minimally invasive technique for direct corneal neurotization to treat neurotrophic keratopathy. METHODS: All cases of corneal neurotization for neurotrophic keratopathy performed by a single surgeon using minima ... Full text Link to item Cite

Influence of Lens Status on Outcomes of Descemet Membrane Endothelial Keratoplasty.

Journal Article Cornea · April 2019 PURPOSE: To evaluate whether lens status influences clinical outcomes of Descemet membrane endothelial keratoplasty (DMEK) in patients who underwent DMEK in phakia, pseudophakia, or combined with cataract surgery (triple). METHODS: A retrospective review o ... Full text Link to item Cite

First report of keratitis in familial cold autoinflammatory syndrome.

Journal Article Can J Ophthalmol · June 2014 OBJECTIVE: To report corneal manifestations of familial cold autoinflammatory syndrome (FCAS) for the first time. DESIGN: small case series PARTICIPANTS: Medical records of three members of a single family were reviewed after obtaining institutional review ... Full text Link to item Cite

Documentation of conformance to preferred practice patterns in caring for patients with dry eye.

Journal Article Arch Ophthalmol · May 2010 OBJECTIVE: To evaluate documentation of physician evaluations of patients with dry eye for the presence of key elements as defined in the American Academy of Ophthalmology Summary Benchmarks for Preferred Practice Patterns. METHODS: One hundred thirty-one ... Full text Link to item Cite

Interleukin-6 as a photoreceptor neuroprotectant in an experimental model of retinal detachment.

Journal Article Invest Ophthalmol Vis Sci · July 2008 PURPOSE: To test the hypothesis that interleukin (IL)-6 prevents photoreceptor cell death during periods of retinal separation from the retinal pigment epithelium (RPE). METHODS: Retinal-RPE separation was created in wild-type C57BL mice, IL-6(-/-) mice, a ... Full text Link to item Cite

Role of the Fas-signaling pathway in photoreceptor neuroprotection.

Journal Article Arch Ophthalmol · October 2007 OBJECTIVE: To determine whether inhibiting the Fas proapoptosis pathway will result in increased photoreceptor survival after separation of the retina from the retinal pigment epithelium (RPE). METHODS: Retina/RPE separation was induced in rat and mouse ey ... Full text Link to item Cite

Comprehensive, Combined Anterior and Transcaruncular Orbital Approach to Medial Canthal Ligament Plication

Journal Article Ophthalmic Plastic & Reconstructive Surgery · September 2007 Full text Cite

Malignant fibrous histiocytoma of the lateral conjunctiva and anterior orbit.

Journal Article Ophthalmic Plast Reconstr Surg · 2007 A 25-year-old woman presented for evaluation of a rapidly enlarging mass of the left bulbar conjunctiva. Debulking biopsy was performed, which led to the diagnosis of myxoid malignant fibrous histiocytoma. The patient underwent left orbital exenteration wi ... Full text Link to item Cite

Cytokeratin 12 in human ocular surface epithelia is the antigen reactive with a commercial anti-Galpha q antibody.

Journal Article Mol Vis · November 16, 2004 PURPOSE: In our initial attempt to identify differentiation markers for ocular surface epithelia, we observed a unique staining pattern by a commercial anti-Galphaq antibody. We further isolate and characterize the protein reactive with this anti-Galphaq a ... Link to item Cite

Identification of the promoter region of the human betaIGH3 gene.

Journal Article Mol Vis · May 18, 2004 PURPOSE: To isolate and characterize the promoter of the human betaIGH3 gene. METHODS: Primer extension and CapSite Hunting methods were used to determine the transcription start sites (TSS) of the human betaIGH3 gene. Putative transcription factor-binding ... Link to item Cite

Distribution of G proteins and RGS proteins on ocular surface epithelia

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · May 1, 2002 Link to item Cite

Growth of epidermal Keratinocytes on human amniotic membrane

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · May 1, 2002 Link to item Cite