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Christopher Ethan Cox

Professor of Medicine
Medicine, Pulmonary, Allergy, and Critical Care Medicine
Duke Box 102043, Durham, NC 27710
Dept of Medicine, Division of Pulmonary and Crit, Durham, NC 27710

Overview


My work is conducted as a clinician, researcher, teacher, and administrator at Duke University.  Currently, I am a Professor of Medicine with Tenure and the Director of the Duke Program to Support People and Enhance Recovery (ProSPER).  My clinical work is based in ICUs at Duke University, though I am also a board-certified palliative medicine specialist.

My research focuses on understanding and improving the experience of critical illness and quality of care for patients, their families and loved ones, clinicians, and society in general.  To do this, my work addresses topics and methodologies including digital technologies, health services research, behavioral and psychological concerns, communication improvement, and decision making support—all in the context of critical care and palliative medicine.  I am very active in clinical trials as well.  Our group is exceedingly, sincerely grateful for having been continuously funded by NIH since 2009.  We cannot thank enough the patients, family members, and clinicians who have been included in our research over the years.

I am very active mentoring others.  Not only is this a true joy, but also how I keep learning from others.

Key interests:  Critical care, healthcare information technology, critical care echocardiography, mobile apps, AI

Current Duke Appointments & Affiliations


Professor of Medicine · 2020 - Present Medicine, Pulmonary, Allergy, and Critical Care Medicine, Medicine

Recent News Items


Published January 29, 2019
A Promising Decision-Making App Falls Short in Aiding Families With Loved Ones on Life Support
Published July 12, 2016
Life Support Decisions: There’s An App for That (almost)
Published June 24, 2014
Dr. Christopher Cox comments: At acute care hospitals, recovery is rare, but comfort is not

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Recent Scholarly Works


Development and usability testing of a Spanish version of a mobile app-based adaptive coping skills intervention for critical illness survivors: Blueprint en español.

Journal article Ann Am Thorac Soc · October 1, 2026 RATIONALE: The exclusion of Spanish-speaking participants in psychobehavioral trials among critical illness survivors limits the generalizability of evidence-based interventions. However, adapting interventions for inclusivity is challenging, and few examp ... Full text Link to item Cite

Patient and Clinician Perspectives on Chronic Pain Communication in Advanced Kidney Disease.

Journal article J Am Geriatr Soc · September 2026 BACKGROUND: Chronic pain is highly prevalent among older adults with advanced chronic kidney disease (CKD stage 4, stage 5, and end-stage kidney disease [ESKD]). Yet, pain management involves a delicate balance between alleviating symptoms and avoiding har ... Full text Open Access Link to item Cite

Predictive Utility of In-Hospital Screening for Postdischarge Depression Symptoms Among Survivors of Critical Illness.

Journal article CHEST Crit Care · September 2026 BACKGROUND: Although postdischarge symptoms of depression are highly prevalent after critical illness, the best timing and strategies for screening are unclear. RESEARCH QUESTION: What is the value of using the 2-item Patient Health Questionnaire (PHQ-2) d ... Full text Link to item Cite
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Recent Grants


2/3 CTSA K12 Program at Duke University

ResearchMentor · Awarded by National Center for Advancing Translational Sciences · 2025 - 2030

Improving needs among older adults: the ICUconnect 2 primary palliative care RCT

ResearchPrincipal Investigator · Awarded by National Institute on Aging · 2024 - 2029

Implementation partner-guided strategy to promote accuracy in ICU prognostication

ResearchPrincipal Investigator · Awarded by National Heart, Lung, and Blood Institute · 2025 - 2029

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Education


Medical University of South Carolina, College of Medicine · 1997 M.D.