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Merlise Clyde

Professor of Statistical Science
Statistical Science
Duke Box 90251, Durham, NC 27708-0251
223E Old Chem Bldg, Box 90251, Durham, NC 27708

Overview


Model uncertainty and choice in prediction and variable selection problems for linear, generalized linear models and multivariate models. Bayesian Model Averaging. Prior distributions for model selection and model averaging. Wavelets and adaptive kernel non-parametric function estimation. Spatial statistics. Experimental design for nonlinear models. Applications in proteomics, bioinformatics, astro-statistics, air pollution and health effects, and environmental sciences.

Office Hours


Fall 2023: 

DGS Office Hours:  Wed 1:30-2:30

STA 702:  Mon 9:00am-10am and Thur 1:30-2:30 pm


or by appointment - send an outlook invite if there are no conflicts!

Current Duke Appointments & Affiliations


Professor of Statistical Science · 2011 - Present Statistical Science, Trinity College of Arts & Sciences
Chair of the Department of Statistical Science · 2025 - Present Statistical Science, Trinity College of Arts & Sciences

Recent News Items


Published March 1, 2023
AmStat News
Celebrating Women in Statistics and Data Science
Published January 12, 2023
Duke Today
Building Hope for Racial Equity Work at Duke in 2023
Published May 22, 2020
Clyde, Reiter Named Institute of Mathematical Statistics Fellows

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Recent Scholarly Works


Invited Discussion of "Model Uncertainty and Missing Data: An Objective Bayesian Perspective" by Gonzalo García-Donato , María Eugenia Castellanos , Stefano Cabras Alicia Quirós , and Anabel Forte

Preprint · December 2, 2025 The article by Garc{í}a-Donato and co-authors addresses the dual challenges of accounting for model uncertainty and missing data within the Gaussian regression frameworks from an objective Bayesian perspective. Thru the use of an imputation $g$-prior that ... Link to item Cite
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Recent Grants


Quantifying and Communicating Numerical Model Uncertainty

ResearchPrincipal Investigator · Awarded by University of North Carolina - Chapel Hill · 2019 - 2021

Statistical and Applied Mathematical Science Institute

ResearchPrincipal Investigator · Awarded by University of North Carolina - Chapel Hill · 2017 - 2020

Models for Consortium Level Analysis of GxE Interaction in Complex Disease

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2012 - 2015

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Education


University of Minnesota, Twin Cities · 1993 Ph.D.
University of California, Riverside · 1988 M.S.
University of Alberta (Canada) · 1986 M.S.
Oregon State University · 1985 B.S.