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Selected Publications


Stress-induced mucin 13 reductions drive intestinal microbiome shifts and despair behaviors.

Journal Article Brain, behavior, and immunity · July 2024 Depression is a prevalent psychological condition with limited treatment options. While its etiology is multifactorial, both chronic stress and changes in microbiome composition are associated with disease pathology. Stress is known to induce microbiome dy ... Full text Cite

Evidence for oligodendrocyte progenitor cell heterogeneity in the adult mouse brain.

Journal Article Scientific reports · July 2022 Oligodendrocyte progenitor cells (OPCs) account for approximately 5% of the adult brain and have been historically studied for their role in myelination. In the adult brain, OPCs maintain their proliferative capacity and ability to differentiate into oligo ... Full text Cite

Stress-induced despair behavior develops independently of the Ahr-RORγt axis in CD4 + cells.

Journal Article Scientific reports · May 2022 Current treatments for major depressive disorder are limited to neuropharmacological approaches and are ineffective for large numbers of patients. Recently, alternative means have been explored to understand the etiology of depression. Specifically, change ... Full text Cite

The Role of Gut Mucins in the Etiology of Depression.

Journal Article Frontiers in behavioral neuroscience · January 2020 Major depressive disorders are global health problems that affect more than 6% of the U.S. population. Despite years of research, the etiology of depression remains unclear. Historically, it was believed that depression started within the central nervous s ... Full text Cite