Crystal Cenell Tyson | Scholars@Duke

Crystal Cenell Tyson
Assistant Professor of Medicine

As a board-certified nephrologist and a certified clinical hypertension specialist (ASH-SCH), I take care of patients with kidney disorders and/or high blood pressure. Patients with chronic kidney disease and high blood pressure have an increased risk for developing complications of cardiovascular disease, such as heart attacks, congestive heart failure, strokes, kidney failure requiring dialysis or a kidney transplant, and a shortened lifespan. My clinical focus is to slow the progression of chronic kidney disease and reduce complications from cardiovascular disease with lifestyle modification. I particularly enjoy treating patients with severe or difficult to control high blood pressure by focusing on finding an effective medication regimen that provides the least side effects, eliminating ineffective medications, simplifying medication schedules, and promoting healthy lifestyle behavior. I see patients 2 days per week in the Duke Nephrology Clinic and the Duke Nephrology Hypertension Clinic.

My research interests are to reduce racial and health disparities among patients with hypertension and chronic kidney disease using lifestyle modifications. My past and current research investigates the effects of diet (i.e., the DASH diet, sodium reduction), exercise, and weight loss on blood pressure and kidney function, as well as the effect of bilateral renal artery denervation on blood pressure.

Office Hours

Duke South Clinic 2B/2C: Tuesdays 8:30a -12:30p
Duke Health Center at North Duke Street: Wednesdays 8:30a - 12:30p

Current Appointments & Affiliations

Assistant Professor of Medicine, Medicine, Nephrology, Medicine 2021
Medical Instructor in the Department of Psychiatry and Behavioral Medicine, Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences, Psychiatry & Behavioral Sciences 2016

Contact Information

2727 Erwin Road, Suite 605, Durham, NC 27705
crystal.simpson@duke.edu (919) 660-6860

Background
Education, Training, & Certifications
- Hypertension Fellowship, Department Of Medicine, Duke University School of Medicine 2012 - 2013
- Nephrology Fellowship, Department Of Medicine, Duke University School of Medicine 2009 - 2012
- Chief Resident, General Internal Medicine, St. John Hospital & Medical Center 2008 - 2009
- Residency, Generalinternal Medicine, St. John Hospital & Medical Center 2005 - 2008
- M.D., Wayne State University, School of Medicine 2005
Previous Appointments & Affiliations
- Assistant Professor of Medicine, Medicine, Nephrology, Medicine 2018 - 2020
- Medical Instructor in the Department of Medicine, Medicine, Nephrology, Medicine 2013 - 2017
Recognition
In the News
- APR 25, 2014 WRAL
  
  Study: Diets rich in veggies, fruits ward off hypertension
Research
Selected Grants
- Diet and Hypertension Management in Chronic Kidney Disease awarded by National Institutes of Health 2019 - 2024
- Using digital health to improve diet quality among adults at risk for cardiovascular disease awarded by National Institutes of Health 2019 - 2024
- Facility and Web-based Approaches to Lifestyle Change in Resistant Hypertension awarded by National Institutes of Health 2014 - 2021
- Identifying Strategies for Effective Weight Management in Diverse Interventions awarded by University of Pittsburgh 2016 - 2019
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Avorgbedor, Forgive, James A. Blumenthal, Alan Hinderliter, Krista Ingle, Pao-Hwa Lin, Linda Craighead, Crystal Tyson, William Kraus, Andrew Sherwood, and Patrick J. Smith. “Inflammation moderates the effects of lifestyle modification on neurocognition among individuals with resistant hypertension.” J Clin Hypertens (Greenwich) 25, no. 1 (January 2023): 106–10. https://doi.org/10.1111/jch.14591.
    Full Text Link to Item
  - Tyson, Crystal C., Laura P. Svetkey, Pao-Hwa Lin, Isa Granados, Danielle Kennedy, Kayla T. Dunbar, Cynthia Redd, Gary Bennett, L Ebony Boulware, and Laura J. Fish. “Self-Perceived Barriers and Facilitators to Dietary Approaches to Stop Hypertension Diet Adherence Among Black Americans With Chronic Kidney Disease: A Qualitative Study.” J Ren Nutr 33, no. 1 (January 2023): 59–68. https://doi.org/10.1053/j.jrn.2022.05.002.
    Full Text Link to Item
  - Lin, Pao-Hwa, and Crystal Tyson. “Fixing America's eating habits with effective stakeholder collaborations.” Nat Med 28, no. 12 (December 2022): 2469–70. https://doi.org/10.1038/s41591-022-02111-8.
    Full Text Link to Item
  - Miller, Hailey N., Miriam B. Berger, Sandy Askew, Elizabeth Trefney, Crystal Tyson, Laura Svetkey, Gary G. Bennett, and Dori M. Steinberg. “Implementation of an At-home Blood Pressure Measurement Protocol in a Hypertension Management Clinical Trial During the COVID-19 Pandemic.” J Cardiovasc Nurs 37, no. 5 (September 2022): 475–81. https://doi.org/10.1097/JCN.0000000000000927.
    Full Text Link to Item
  - Smith, Patrick J., Andrew Sherwood, Alan L. Hinderliter, Stephanie Mabe, Lana L. Watkins, Linda Craighead, Krista Ingle, et al. “Lifestyle modification and cognitive function among individuals with resistant hypertension: cognitive outcomes from the TRIUMPH trial.” J Hypertens 40, no. 7 (July 1, 2022): 1359–68. https://doi.org/10.1097/HJH.0000000000003151.
    Full Text Link to Item
  - Smith, Patrick J., Andrew Sherwood, Alan L. Hinderliter, Stephanie Mabe, Crystal Tyson, Forgive Avorgbedor, Lana L. Watkins, Pao-Hwa Lin, William E. Kraus, and James A. Blumenthal. “Cerebrovascular Function, Vascular Risk, and Lifestyle Patterns in Resistant Hypertension.” J Alzheimers Dis 87, no. 1 (2022): 345–57. https://doi.org/10.3233/JAD-215522.
    Full Text Link to Item
  - Bhavsar, Nrupen A., Clemontina A. Davenport, Lexie Zidanyue Yang, Sarah Peskoe, Julia J. Scialla, Rasheeda K. Hall, Crystal C. Tyson, et al. “Psychosocial determinants of cardiovascular events among black Americans with chronic kidney disease or associated risk factors in the Jackson heart study.” Bmc Nephrology 22, no. 1 (November 2021): 375. https://doi.org/10.1186/s12882-021-02594-6.
    Full Text
  - Blumenthal, James A., Alan L. Hinderliter, Patrick J. Smith, Stephanie Mabe, Lana L. Watkins, Linda Craighead, Krista Ingle, et al. “Effects of Lifestyle Modification on Patients With Resistant Hypertension: Results of the TRIUMPH Randomized Clinical Trial.” Circulation 144, no. 15 (October 12, 2021): 1212–26. https://doi.org/10.1161/CIRCULATIONAHA.121.055329.
    Full Text Link to Item
  - Miller, Hailey N., Miriam B. Berger, Sandy Askew, Melissa C. Kay, Christina M. Hopkins, Meghana Sai Iragavarapu, Mia de Leon, et al. “The Nourish Protocol: A digital health randomized controlled trial to promote the DASH eating pattern among adults with hypertension.” Contemp Clin Trials 109 (October 2021): 106539. https://doi.org/10.1016/j.cct.2021.106539.
    Full Text Link to Item
  - Mitchell, Nia S., Bryan C. Batch, and Crystal C. Tyson. “Retrospective cohort study of changes in estimated glomerular filtration rate for patients prescribed a low carb diet.” Curr Opin Endocrinol Diabetes Obes 28, no. 5 (October 1, 2021): 480–87. https://doi.org/10.1097/MED.0000000000000673.
    Full Text Open Access Copy Link to Item
  - Tyson, Crystal C., Alison Luciano, Jennifer L. Modliszewski, David L. Corcoran, James R. Bain, Michael Muehlbauer, Olga Ilkayeva, et al. “Effect of Bicarbonate on Net Acid Excretion, Blood Pressure, and Metabolism in Patients With and Without CKD: The Acid Base Compensation in CKD Study.” Am J Kidney Dis 78, no. 1 (July 2021): 38–47. https://doi.org/10.1053/j.ajkd.2020.10.015.
    Full Text Link to Item
  - Pourafshar, Shirin, Mira Nicchitta, Crystal C. Tyson, Laura P. Svetkey, David L. Corcoran, James R. Bain, Michael J. Muehlbauer, et al. “Urine and Plasma Metabolome of Healthy Adults Consuming the DASH (Dietary Approaches to Stop Hypertension) Diet: A Randomized Pilot Feeding Study.” Nutrients 13, no. 6 (May 22, 2021). https://doi.org/10.3390/nu13061768.
    Full Text Link to Item
  - Tyson, Crystal C., Clemontina A. Davenport, Pao-Hwa Lin, Julia J. Scialla, Rasheeda Hall, Clarissa J. Diamantidis, Joseph Lunyera, et al. “DASH Diet and Blood Pressure Among Black Americans With and Without CKD: The Jackson Heart Study.” Am J Hypertens 32, no. 10 (September 24, 2019): 975–82. https://doi.org/10.1093/ajh/hpz090.
    Full Text Link to Item
  - Hall, Rasheeda K., Clemontina A. Davenport, Mario Sims, Cathleen Colón-Emeric, Tiffany Washington, Jennifer St Clair Russell, Jane Pendergast, et al. “Association of functional and structural social support with chronic kidney disease among African Americans: the Jackson Heart Study.” Bmc Nephrol 20, no. 1 (July 15, 2019): 262. https://doi.org/10.1186/s12882-019-1432-9.
    Full Text Link to Item
  - Böhm, Michael, Felix Mahfoud, Raymond R. Townsend, David E. Kandzari, Stuart Pocock, Christian Ukena, Michael A. Weber, et al. “Ambulatory heart rate reduction after catheter-based renal denervation in hypertensive patients not receiving anti-hypertensive medications: data from SPYRAL HTN-OFF MED, a randomized, sham-controlled, proof-of-concept trial.” Eur Heart J 40, no. 9 (March 1, 2019): 743–51. https://doi.org/10.1093/eurheartj/ehy871.
    Full Text Link to Item
  - Diamantidis, Clarissa J., Clemontina A. Davenport, Joseph Lunyera, Nrupen Bhavsar, Julia Scialla, Rasheeda Hall, Crystal Tyson, et al. “Low use of routine medical care among African Americans with high CKD risk: the Jackson Heart Study.” Bmc Nephrol 20, no. 1 (January 10, 2019): 11. https://doi.org/10.1186/s12882-018-1190-0.
    Full Text Open Access Copy Link to Item
  - Olivo, Robert E., Sarah L. Hale, Clarissa J. Diamantidis, Nrupen A. Bhavsar, Crystal C. Tyson, Katherine L. Tucker, Teresa C. Carithers, et al. “Dietary Phosphorus and Ambulatory Blood Pressure in African Americans: The Jackson Heart Study.” Am J Hypertens 32, no. 1 (January 1, 2019): 94–103. https://doi.org/10.1093/ajh/hpy126.
    Full Text Link to Item
  - Lin, Pao-Hwa, Steven Grambow, Stephen Intille, John A. Gallis, Tony Lazenka, Hayden Bosworth, Corrine L. Voils, et al. “The Association Between Engagement and Weight Loss Through Personal Coaching and Cell Phone Interventions in Young Adults: Randomized Controlled Trial.” Jmir Mhealth Uhealth 6, no. 10 (October 18, 2018): e10471. https://doi.org/10.2196/10471.
    Full Text Link to Item
  - Kario, Kazuomi, Michael Böhm, Felix Mahfoud, Raymond R. Townsend, Michael A. Weber, Manesh Patel, Crystal C. Tyson, et al. “Twenty-Four-Hour Ambulatory Blood Pressure Reduction Patterns After Renal Denervation in the SPYRAL HTN-OFF MED Trial.” Circulation 138, no. 15 (October 9, 2018): 1602–4. https://doi.org/10.1161/CIRCULATIONAHA.118.035588.
    Full Text Link to Item
  - Tyson, Crystal C., and Christina M. Wyatt. “There's no place like home: is self-monitoring beneficial in hypertension management?” Kidney Int 94, no. 3 (September 2018): 450–52. https://doi.org/10.1016/j.kint.2018.06.021.
    Full Text Link to Item
  - Olivo, Robert E., Clemontina A. Davenport, Clarissa J. Diamantidis, Nrupen A. Bhavsar, Crystal C. Tyson, Rasheeda Hall, Aurelian Bidulescu, et al. “Obesity and synergistic risk factors for chronic kidney disease in African American adults: the Jackson Heart Study.” Nephrol Dial Transplant 33, no. 6 (June 1, 2018): 992–1001. https://doi.org/10.1093/ndt/gfx230.
    Full Text Link to Item
  - Lunyera, Joseph, Clemontina A. Davenport, Nrupen A. Bhavsar, Mario Sims, Julia Scialla, Jane Pendergast, Rasheeda Hall, et al. “Nondepressive Psychosocial Factors and CKD Outcomes in Black Americans.” Clin J Am Soc Nephrol 13, no. 2 (February 7, 2018): 213–22. https://doi.org/10.2215/CJN.06430617.
    Full Text Link to Item
  - Tyson, Crystal C., Huiman Barnhart, Shelly Sapp, Victor Poon, Pao-Hwa Lin, and Laura P. Svetkey. “Ambulatory blood pressure in the dash diet trial: Effects of race and albuminuria.” J Clin Hypertens (Greenwich) 20, no. 2 (February 2018): 308–14. https://doi.org/10.1111/jch.13170.
    Full Text Link to Item
  - Tyson, Crystal C., Patrick J. Smith, Andrew Sherwood, Stephanie Mabe, Alan L. Hinderliter, and James A. Blumenthal. “Association between normal or mildly reduced kidney function, cardiovascular risk and biomarkers for atherosclerosis: results from the ENCORE trial.” Clin Kidney J 10, no. 5 (October 2017): 666–71. https://doi.org/10.1093/ckj/sfx025.
    Full Text Link to Item
  - Tyson, Crystal C., and Thomas M. Coffman. “In the Wake of Systolic Blood Pressure Intervention Trial: New Targets for Improving Hypertension Management in Chronic Kidney Disease?” Nephron 135, no. 4 (2017): 287–90. https://doi.org/10.1159/000455130.
    Full Text Link to Item
  - Tyson, Crystal C., Patrick J. Smith, Andrew Sherwood, Stephanie Mabe, Alan L. Hinderliter, and James A. Blumenthal. “Influence of Kidney Function on Blood Pressure Response to Lifestyle Modifications: Secondary Analysis From the Exercise and Nutritional Interventions for Cardiovascular Health (ENCORE) Trial.” J Clin Hypertens (Greenwich) 18, no. 12 (December 2016): 1260–67. https://doi.org/10.1111/jch.12853.
    Full Text Link to Item
  - Tyson, Crystal C., Pao-Hwa Lin, Leonor Corsino, Bryan C. Batch, Jenifer Allen, Shelly Sapp, Huiman Barnhart, Chinazo Nwankwo, Jasmine Burroughs, and Laura P. Svetkey. “Short-term effects of the DASH diet in adults with moderate chronic kidney disease: a pilot feeding study.” Clin Kidney J 9, no. 4 (August 2016): 592–98. https://doi.org/10.1093/ckj/sfw046.
    Full Text Open Access Copy Link to Item
  - Coughlin, Janelle W., Phillip J. Brantley, Catherine M. Champagne, William M. Vollmer, Victor J. Stevens, Kristine Funk, Arlene T. Dalcin, et al. “The impact of continued intervention on weight: Five-year results from the weight loss maintenance trial.” Obesity (Silver Spring) 24, no. 5 (May 2016): 1046–53. https://doi.org/10.1002/oby.21454.
    Full Text Link to Item
  - Svetkey, Laura P., Bryan C. Batch, Pao-Hwa Lin, Stephen S. Intille, Leonor Corsino, Crystal C. Tyson, Hayden B. Bosworth, et al. “Erratum: Cell phone intervention for you (CITY): A randomized, controlled trial of behavioral weight loss intervention for young adults using mobile technology.” Obesity (Silver Spring) 24, no. 2 (February 2016): 536. https://doi.org/10.1002/oby.21433.
    Full Text Link to Item
  - Lin, Pao-Hwa, Stephen Intille, Gary Bennett, Hayden B. Bosworth, Leonor Corsino, Corrine Voils, Steven Grambow, et al. “Adaptive intervention design in mobile health: Intervention design and development in the Cell Phone Intervention for You trial.” Clin Trials 12, no. 6 (December 2015): 634–45. https://doi.org/10.1177/1740774515597222.
    Full Text Open Access Copy Link to Item
  - Blumenthal, James A., Andrew Sherwood, Patrick J. Smith, Stephanie Mabe, Lana Watkins, Pao-Hwa Lin, Linda W. Craighead, et al. “Lifestyle modification for resistant hypertension: The TRIUMPH randomized clinical trial.” Am Heart J 170, no. 5 (November 2015): 986-994.e5. https://doi.org/10.1016/j.ahj.2015.08.006.
    Full Text Link to Item
  - Svetkey, Laura P., Bryan C. Batch, Pao-Hwa Lin, Stephen S. Intille, Leonor Corsino, Crystal C. Tyson, Hayden B. Bosworth, et al. “Cell phone intervention for you (CITY): A randomized, controlled trial of behavioral weight loss intervention for young adults using mobile technology.” Obesity (Silver Spring) 23, no. 11 (November 2015): 2133–41. https://doi.org/10.1002/oby.21226.
    Full Text Link to Item
  - Fitzpatrick, Stephanie L., Janelle W. Coughlin, Lawrence J. Appel, Crystal Tyson, Victor J. Stevens, Gerald J. Jerome, Arlene Dalcin, Phillip J. Brantley, and Felicia Hill-Briggs. “Application of Latent Class Analysis to Identify Behavioral Patterns of Response to Behavioral Lifestyle Interventions in Overweight and Obese Adults.” Int J Behav Med 22, no. 4 (August 2015): 471–80. https://doi.org/10.1007/s12529-014-9446-y.
    Full Text Open Access Copy Link to Item
  - Vemulapalli, Sreekanth, Crystal C. Tyson, and Laura P. Svetkey. “Apparent treatment-resistant hypertension and chronic kidney disease: another cardiovascular-renal syndrome?” Adv Chronic Kidney Dis 21, no. 6 (November 2014): 489–99. https://doi.org/10.1053/j.ackd.2014.08.006.
    Full Text Open Access Copy Link to Item
  - Batch, B. C., C. Tyson, J. Bagwell, L. Corsino, S. Intille, P. H. Lin, T. Lazenka, et al. “Corrigendum to "Weight loss intervention for young adults using mobile technology: Design and rationale of a randomized controlled trial - Cell phone Intervention for You (CITY)" [Contemp Clin Trials 37/2 (2014) 333-341].” Contemp Clin Trials 39, no. 2 (November 2014): 351. https://doi.org/10.1016/j.cct.2014.10.001.
    Full Text Link to Item
  - Batch, Bryan C., Crystal Tyson, Jacqueline Bagwell, Leonor Corsino, Stephen Intille, Pao-Hwa Lin, Tony Lazenka, et al. “Weight loss intervention for young adults using mobile technology: design and rationale of a randomized controlled trial - Cell Phone Intervention for You (CITY).” Contemp Clin Trials 37, no. 2 (March 2014): 333–41. https://doi.org/10.1016/j.cct.2014.01.003.
    Full Text Open Access Copy Link to Item
  - Tyson, Crystal C., Maragatha Kuchibhatla, Uptal D. Patel, Patrick H. Pun, Alex Chang, Chinazo Nwankwo, Michael A. Joseph, and Laura P. Svetkey. “Impact of Kidney Function on Effects of the Dietary Approaches to Stop Hypertension (Dash) Diet.” J Hypertens (Los Angel) 3 (2014). https://doi.org/10.4172/2167-1095.1000168.
    Full Text Open Access Copy Link to Item
  - Chang, Alex, Bryan C. Batch, Heather L. McGuire, William M. Vollmer, Laura P. Svetkey, Crystal C. Tyson, Anawin Sanguankeo, Cheryl Anderson, Jessica Houston, and Lawrence J. Appel. “Association of a reduction in central obesity and phosphorus intake with changes in urinary albumin excretion: the PREMIER study.” Am J Kidney Dis 62, no. 5 (November 2013): 900–907. https://doi.org/10.1053/j.ajkd.2013.04.022.
    Full Text Open Access Copy Link to Item
  - Tyson, Crystal C., Lawrence J. Appel, William M. Vollmer, Gerald J. Jerome, Phillip J. Brantley, Jack F. Hollis, Victor J. Stevens, Jamy D. Ard, Uptal D. Patel, and Laura P. Svetkey. “Impact of 5-year weight change on blood pressure: results from the Weight Loss Maintenance trial.” J Clin Hypertens (Greenwich) 15, no. 7 (July 2013): 458–64. https://doi.org/10.1111/jch.12108.
    Full Text Open Access Copy Link to Item
  - Corsino, Leonor, Pao-Hwa Lin, Bryan C. Batch, Stephen Intille, Steven C. Grambow, Hayden B. Bosworth, Gary G. Bennett, Crystal Tyson, Laura P. Svetkey, and Corrine I. Voils. “Recruiting young adults into a weight loss trial: report of protocol development and recruitment results.” Contemp Clin Trials 35, no. 2 (July 2013): 1–7. https://doi.org/10.1016/j.cct.2013.04.002.
    Full Text Open Access Copy Link to Item
  - Tyson, Crystal C., Chinazo Nwankwo, Pao-Hwa Lin, and Laura P. Svetkey. “The Dietary Approaches to Stop Hypertension (DASH) eating pattern in special populations.” Curr Hypertens Rep 14, no. 5 (October 2012): 388–96. https://doi.org/10.1007/s11906-012-0296-1.
    Full Text Open Access Copy Link to Item
- Book Sections
  - Lin, P. H., C. C. Tyson, B. C. Batch, and L. P. Svetkey. “Nutrition, lifestyle, and hypertension.” In Nutrition in the Prevention and Treatment of Disease, 625–55, 2017. https://doi.org/10.1016/B978-0-12-802928-2.00028-X.
    Full Text

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.

Education, Training, & Certifications

Previous Appointments & Affiliations

In the News

Selected Grants

Selected Publications

Academic Articles

Book Sections