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Crystal Cenell Tyson

Assistant Professor of Medicine
Medicine, Nephrology
2727 Erwin Road, Suite 605, Durham, NC 27705

Overview


As a board-certified nephrologist and a certified clinical hypertension specialist (ASH-SCH), I take care of patients with kidney disorders and/or high blood pressure. Patients with chronic kidney disease and high blood pressure have an increased risk for developing complications of cardiovascular disease, such as heart attacks, congestive heart failure, strokes, kidney failure requiring dialysis or a kidney transplant, and a shortened lifespan. My clinical focus is to slow the progression of chronic kidney disease and reduce complications from cardiovascular disease with lifestyle modification. I particularly enjoy treating patients with severe or difficult to control high blood pressure by focusing on finding an effective medication regimen that provides the least side effects, eliminating ineffective medications, simplifying medication schedules, and promoting healthy lifestyle behavior. I see patients 2 days per week in the Duke Nephrology Clinic and the Duke Nephrology Hypertension Clinic.

My research interests are to reduce racial and health disparities among patients with hypertension and chronic kidney disease using lifestyle modifications. My past and current research investigates the effects of diet (i.e., the DASH diet, sodium reduction), exercise, and weight loss on blood pressure and kidney function, as well as the effect of bilateral renal artery denervation on blood pressure.

Office Hours


Duke South Clinic 2B/2C: Tuesdays 8:30a -12:30p
Duke Health Center at North Duke Street: Wednesdays 8:30a - 12:30p

Current Appointments & Affiliations


Assistant Professor of Medicine · 2021 - Present Medicine, Nephrology, Medicine
Medical Instructor in the Department of Psychiatry and Behavioral Medicine · 2016 - Present Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences, Psychiatry & Behavioral Sciences

In the News


Published April 25, 2014
Study: Diets rich in veggies, fruits ward off hypertension

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Recent Publications


Lifestyle, sleep quality, and cognitive function in resistant hypertension: One-year follow-up from the TRIUMPH trial.

Journal Article J Alzheimers Dis · February 2026 BackgroundTreatment resistant hypertension (TRH) is associated with increased risk of cognitive decline, which may be reduced by healthy lifestyle changes.ObjectiveTo examine the effects of a comprehensive, rehabilitation-based lifestyle hprogram on cognit ... Full text Link to item Cite

Effects of a Digital Intervention to Improve DASH and Blood Pressure Among US Adults.

Journal Article Hypertension · February 2025 BACKGROUND: Dietary Approaches to Stop Hypertension (DASH) is a recommended first-line treatment for adults with hypertension, yet adherence to DASH is low. To evaluate the efficacy of a digital health intervention (DHI), compared with attention control, o ... Full text Link to item Cite

The DASH Dietary Pattern

Chapter · January 1, 2025 The Dietary Approaches to Stop Hypertension (DASH) diet is an evidence-based dietary pattern that is effective in lowering blood pressure (BP), improving lipids, and achieving weight control. The blood pressure-lowering benefit of the DASH dietary pattern ... Full text Cite
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Recent Grants


Cardiorenal Genomics for Risk Prediction in African American Descent Populations

ResearchCo Investigator · Awarded by University of Alabama at Birmingham · 2023 - 2027

Multi-component Lifestyle Intervention to improve cardiovascular outcomes in chronic kidney disease (R61/R33)

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2025 - 2027

Planning grant for clinical trial of REACH-Hypertension curriculum for clinicians

ResearchCo Investigator · Awarded by National Heart, Lung, and Blood Institute · 2024 - 2027

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Education


Wayne State University, School of Medicine · 2005 M.D.