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Cynthia Dianne Guy

Professor of Pathology
Pathology
Duke Box 3712, Durham, NC 27710
206 A Davison Bldg, Durham, NC

Overview


My research interests include:
Fine Needle Aspiration of Liver, Gastrointestinal Tract, and Pancreatic Lesions
Biliary Duct Brushings
Nonalcoholic Fatty Liver Disease/NASH
Liver Fibrogenesis

Current Appointments & Affiliations


Professor of Pathology · 2021 - Present Pathology, Clinical Science Departments
Professor of Medicine · 2020 - Present Medicine, Gastroenterology, Medicine

Recent Publications


Identification of Potential Therapeutic Targets Against Anthrax-Toxin-Induced Liver and Heart Damage.

Journal Article Toxins (Basel) · January 24, 2025 Anthrax represents a disease resulting from infection by toxin-secreting bacteria, Bacillus anthracis. This research aimed to identify new therapeutic targets to combat anthrax. We performed assays to assess cell viability, apoptosis, glycogen consumption, ... Full text Link to item Cite

MASLD in people with HIV exhibits higher fibrosis stage despite lower disease activity than in matched controls.

Journal Article Aliment Pharmacol Ther · November 2024 BACKGROUND: Metabolic dysfunction-associated steatotic liver disease (MASLD) is common in people with HIV (PWH). The morphological spectrum of MASLD compared to matched controls and of the correlation between the NAFLD activity score (NAS) and fibrosis sta ... Full text Link to item Cite

Alterations in zonal distribution and plasma membrane localization of hepatocyte bile acid transporters in patients with NAFLD.

Journal Article Hepatol Commun · March 1, 2024 BACKGROUND: NAFLD is highly prevalent with limited treatment options. Bile acids (BAs) increase in the systemic circulation and liver during NAFLD progression. Changes in plasma membrane localization and zonal distribution of BA transporters can influence ... Full text Link to item Cite
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Recent Grants


Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN)

ResearchPathologist · Awarded by National Institutes of Health · 2004 - 2027

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Education, Training & Certifications


Medical University of South Carolina, College of Medicine · 1993 M.D.
University of North Carolina, Chapel Hill · 1985 B.A.