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Dana Kristine Pasquale

Assistant Professor in Population Health Sciences
Population Health Sciences
215 Morris Street, Suite 210, Durham, NC 27701
215 Morris Street, Suite 210, Durham, NC 27701

Selected Publications


A New Paradigm for Pandemic Preparedness

Journal Article Current Epidemiology Reports · November 9, 2023 AbstractPurpose of ReviewPreparing for pandemics requires a degree of interdisciplinary work that is challenging under the current paradigm. This review s ... Full text Cite

Scalable Strategies to Increase Efficiency and Augment Public Health Activities During Epidemic Peaks.

Journal Article J Public Health Manag Pract · November 2023 OBJECTIVE: Scalable strategies to reduce the time burden and increase contact tracing efficiency are crucial during early waves and peaks of infectious transmission. DESIGN: We enrolled a cohort of SARS-CoV-2-positive seed cases into a peer recruitment stu ... Full text Link to item Cite

A method for intelligent allocation of diagnostic testing by leveraging data from commercial wearable devices: a case study on COVID-19.

Journal Article NPJ Digit Med · September 1, 2022 Mass surveillance testing can help control outbreaks of infectious diseases such as COVID-19. However, diagnostic test shortages are prevalent globally and continue to occur in the US with the onset of new COVID-19 variants and emerging diseases like monke ... Full text Link to item Cite

Brief Report: Blood and Genital Fluid Viral Load Trajectories Among Treated and Untreated Persons With Acute HIV Infection in Malawi.

Journal Article J Acquir Immune Defic Syndr · May 1, 2022 BACKGROUND: Persons with acute HIV infection (AHI) are highly infectious and responsible for a disproportionate share of incident infections. Immediate antiretroviral therapy (ART) rapidly reduces blood viral loads (VLs), but genital VLs after ART initiati ... Full text Link to item Cite

A Method for Intelligent Allocation of Diagnostic Testing by Leveraging Data from Commercial Wearable Devices: A Case Study on COVID-19.

Journal Article Res Sq · April 1, 2022 Mass surveillance testing can help control outbreaks of infectious diseases such as COVID-19. However, diagnostic test shortages are prevalent globally and continue to occur in the US with the onset of new COVID-19 variants, demonstrating an unprecedented ... Full text Link to item Cite

Intersection of Syphilis and Human Immunodeficiency Virus (HIV) Networks to Identify Opportunities to Enhance HIV Prevention.

Journal Article Clin Infect Dis · February 11, 2022 BACKGROUND: Human immunodeficiency virus (HIV) and syphilis infection continue at disproportionate rates among minority men who have sex with men (MSM) in the United States. The integration of HIV genetic clustering with partner services can provide import ... Full text Link to item Cite

Visualizing COVID Restrictions: Activity Patterns Before, During, and After COVID-19 Lockdowns in Uttar Pradesh, India.

Journal Article Socius · 2022 Globally, restrictions implemented to limit the spread of COVID-19 have highlighted deeply rooted social divisions, raising concerns about differential impacts on members of different groups. Inequalities among households of different castes are ubiquitous ... Full text Open Access Link to item Cite

Harnessing the Power of Smart and Connected Health to Tackle COVID-19: IoT, AI, Robotics, and Blockchain for a Better World.

Journal Article IEEE Internet Things J · August 15, 2021 As COVID-19 hounds the world, the common cause of finding a swift solution to manage the pandemic has brought together researchers, institutions, governments, and society at large. The Internet of Things (IoT), artificial intelligence (AI)-including machin ... Full text Link to item Cite

Are skin color and body mass index associated with social network structure? Findings from a male sex market study.

Journal Article Ethn Health · August 2021 Objectives: There is a growing burden of HIV and sex-related diseases in South Asia and India. Sociological research illustrates that key axes of social stratification, such as race and ethnicity, affect social network structure which, in turn, impacts sex ... Full text Link to item Cite

Lost and found: applying network analysis to public health contact tracing for HIV.

Journal Article Appl Netw Sci · 2021 Infectious disease surveillance is often case-based, focused on people diagnosed and their contacts in a predefined time window, and treated as independent across infections. Network analysis of partners and contacts joining multiple investigations and inf ... Full text Open Access Link to item Cite

Homophily in risk and behavior complicate understanding the COVID-19 epidemic curve

Journal Article · 2021 New COVID-19 diagnoses have dropped faster than expected in the United States. Interpretations of the decrease have focused on changing factors (e.g. mask-wearing, vaccines, etc.), but predictive models largely ignore heterogeneity in behaviorally-driven e ... Full text Cite

Community Effectiveness of Masks and Vaccines.

Journal Article Socius · 2021 Recent controversies about wearing masks and getting vaccinated to slow the spread of coronavirus disease 2019 highlight the potential for individual rights and decision making to create widespread community-level outcomes. There is little work demonstrati ... Full text Link to item Cite

Factors Associated With Human Immunodeficiency Virus Infections Linked in Genetic Clusters But Disconnected in Partner Tracing.

Journal Article Sex Transm Dis · February 2020 BACKGROUND: Successful partner notification can improve community-level outcomes by increasing the proportion of persons living with human immunodeficiency virus (HIV) who are linked to HIV care and virally suppressed, but it is resource intensive. Underst ... Full text Link to item Cite

Human Immunodeficiency Virus (HIV)-1 Transmission Among Persons With Acute HIV-1 Infection in Malawi: Demographic, Behavioral, and Phylogenetic Relationships.

Journal Article Clin Infect Dis · August 16, 2019 BACKGROUND: Understanding sexual networks involving acute human immunodeficiency virus (HIV)-1 infections (AHI) may lead to prevention opportunities to mitigate high rates of onward transmission. We evaluated HIV-1 phylogenetic and behavioral characteristi ... Full text Link to item Cite

Prediction of HIV Transmission Cluster Growth With Statewide Surveillance Data.

Journal Article J Acquir Immune Defic Syndr · February 1, 2019 BACKGROUND: Prediction of HIV transmission cluster growth may help guide public health action. We developed a predictive model for cluster growth in North Carolina (NC) using routine HIV surveillance data. METHODS: We identified putative transmission clust ... Full text Link to item Cite

Randomized Controlled Pilot Study of Antiretrovirals and a Behavioral Intervention for Persons With Acute HIV Infection: Opportunity for Interrupting Transmission.

Journal Article Open Forum Infect Dis · January 2019 BACKGROUND: Persons with acute HIV infection (AHI) have heightened transmission risk. We evaluated potential transmission reduction using behavioral and biomedical interventions in a randomized controlled pilot study in Malawi. METHODS: Persons were random ... Full text Link to item Cite

Sustained Sexual Behavior Change After Acute HIV Diagnosis in Malawi.

Journal Article Sex Transm Dis · November 2018 BACKGROUND: Identification of acute HIV infection (AHI) allows for important opportunities for HIV prevention through behavior change and biomedical intervention. Here, we evaluate changes in sexual risk behaviors among persons with AHI enrolled in a combi ... Full text Link to item Cite

Leveraging Phylogenetics to Understand HIV Transmission and Partner Notification Networks.

Journal Article J Acquir Immune Defic Syndr · August 1, 2018 BACKGROUND: Partner notification is an important component of public health test and treat interventions. To enhance this essential function, we assessed the potential for molecular methods to supplement routine partner notification and corroborate HIV net ... Full text Link to item Cite

Integration of Contact Tracing and Phylogenetics in an Investigation of Acute HIV Infection.

Journal Article Sex Transm Dis · April 2018 BACKGROUND: The integration of traditional contact tracing with HIV sequence analyses offers opportunities to mitigate some of the barriers to effective network construction. We used combined analyses during an outbreak investigation of spatiotemporally cl ... Full text Link to item Cite

Incorporating Acute HIV Screening into Routine HIV Testing at Sexually Transmitted Infection Clinics, and HIV Testing and Counseling Centers in Lilongwe, Malawi.

Journal Article J Acquir Immune Defic Syndr · March 1, 2016 BACKGROUND AND OBJECTIVES: Integrating acute HIV-infection (AHI) testing into clinical settings is critical to prevent transmission, and realize potential treatment-as-prevention benefits. We evaluated acceptability of AHI testing and compared AHI prevalen ... Full text Link to item Cite

A New Paradigm for Pandemic Preparedness

Journal Article Current Epidemiology Reports · November 9, 2023 AbstractPurpose of ReviewPreparing for pandemics requires a degree of interdisciplinary work that is challenging under the current paradigm. This review s ... Full text Cite

Scalable Strategies to Increase Efficiency and Augment Public Health Activities During Epidemic Peaks.

Journal Article J Public Health Manag Pract · November 2023 OBJECTIVE: Scalable strategies to reduce the time burden and increase contact tracing efficiency are crucial during early waves and peaks of infectious transmission. DESIGN: We enrolled a cohort of SARS-CoV-2-positive seed cases into a peer recruitment stu ... Full text Link to item Cite

A method for intelligent allocation of diagnostic testing by leveraging data from commercial wearable devices: a case study on COVID-19.

Journal Article NPJ Digit Med · September 1, 2022 Mass surveillance testing can help control outbreaks of infectious diseases such as COVID-19. However, diagnostic test shortages are prevalent globally and continue to occur in the US with the onset of new COVID-19 variants and emerging diseases like monke ... Full text Link to item Cite

Brief Report: Blood and Genital Fluid Viral Load Trajectories Among Treated and Untreated Persons With Acute HIV Infection in Malawi.

Journal Article J Acquir Immune Defic Syndr · May 1, 2022 BACKGROUND: Persons with acute HIV infection (AHI) are highly infectious and responsible for a disproportionate share of incident infections. Immediate antiretroviral therapy (ART) rapidly reduces blood viral loads (VLs), but genital VLs after ART initiati ... Full text Link to item Cite

A Method for Intelligent Allocation of Diagnostic Testing by Leveraging Data from Commercial Wearable Devices: A Case Study on COVID-19.

Journal Article Res Sq · April 1, 2022 Mass surveillance testing can help control outbreaks of infectious diseases such as COVID-19. However, diagnostic test shortages are prevalent globally and continue to occur in the US with the onset of new COVID-19 variants, demonstrating an unprecedented ... Full text Link to item Cite

Intersection of Syphilis and Human Immunodeficiency Virus (HIV) Networks to Identify Opportunities to Enhance HIV Prevention.

Journal Article Clin Infect Dis · February 11, 2022 BACKGROUND: Human immunodeficiency virus (HIV) and syphilis infection continue at disproportionate rates among minority men who have sex with men (MSM) in the United States. The integration of HIV genetic clustering with partner services can provide import ... Full text Link to item Cite

Visualizing COVID Restrictions: Activity Patterns Before, During, and After COVID-19 Lockdowns in Uttar Pradesh, India.

Journal Article Socius · 2022 Globally, restrictions implemented to limit the spread of COVID-19 have highlighted deeply rooted social divisions, raising concerns about differential impacts on members of different groups. Inequalities among households of different castes are ubiquitous ... Full text Open Access Link to item Cite

Harnessing the Power of Smart and Connected Health to Tackle COVID-19: IoT, AI, Robotics, and Blockchain for a Better World.

Journal Article IEEE Internet Things J · August 15, 2021 As COVID-19 hounds the world, the common cause of finding a swift solution to manage the pandemic has brought together researchers, institutions, governments, and society at large. The Internet of Things (IoT), artificial intelligence (AI)-including machin ... Full text Link to item Cite

Are skin color and body mass index associated with social network structure? Findings from a male sex market study.

Journal Article Ethn Health · August 2021 Objectives: There is a growing burden of HIV and sex-related diseases in South Asia and India. Sociological research illustrates that key axes of social stratification, such as race and ethnicity, affect social network structure which, in turn, impacts sex ... Full text Link to item Cite

Lost and found: applying network analysis to public health contact tracing for HIV.

Journal Article Appl Netw Sci · 2021 Infectious disease surveillance is often case-based, focused on people diagnosed and their contacts in a predefined time window, and treated as independent across infections. Network analysis of partners and contacts joining multiple investigations and inf ... Full text Open Access Link to item Cite

Homophily in risk and behavior complicate understanding the COVID-19 epidemic curve

Journal Article · 2021 New COVID-19 diagnoses have dropped faster than expected in the United States. Interpretations of the decrease have focused on changing factors (e.g. mask-wearing, vaccines, etc.), but predictive models largely ignore heterogeneity in behaviorally-driven e ... Full text Cite

Community Effectiveness of Masks and Vaccines.

Journal Article Socius · 2021 Recent controversies about wearing masks and getting vaccinated to slow the spread of coronavirus disease 2019 highlight the potential for individual rights and decision making to create widespread community-level outcomes. There is little work demonstrati ... Full text Link to item Cite

Factors Associated With Human Immunodeficiency Virus Infections Linked in Genetic Clusters But Disconnected in Partner Tracing.

Journal Article Sex Transm Dis · February 2020 BACKGROUND: Successful partner notification can improve community-level outcomes by increasing the proportion of persons living with human immunodeficiency virus (HIV) who are linked to HIV care and virally suppressed, but it is resource intensive. Underst ... Full text Link to item Cite

Human Immunodeficiency Virus (HIV)-1 Transmission Among Persons With Acute HIV-1 Infection in Malawi: Demographic, Behavioral, and Phylogenetic Relationships.

Journal Article Clin Infect Dis · August 16, 2019 BACKGROUND: Understanding sexual networks involving acute human immunodeficiency virus (HIV)-1 infections (AHI) may lead to prevention opportunities to mitigate high rates of onward transmission. We evaluated HIV-1 phylogenetic and behavioral characteristi ... Full text Link to item Cite

Prediction of HIV Transmission Cluster Growth With Statewide Surveillance Data.

Journal Article J Acquir Immune Defic Syndr · February 1, 2019 BACKGROUND: Prediction of HIV transmission cluster growth may help guide public health action. We developed a predictive model for cluster growth in North Carolina (NC) using routine HIV surveillance data. METHODS: We identified putative transmission clust ... Full text Link to item Cite

Randomized Controlled Pilot Study of Antiretrovirals and a Behavioral Intervention for Persons With Acute HIV Infection: Opportunity for Interrupting Transmission.

Journal Article Open Forum Infect Dis · January 2019 BACKGROUND: Persons with acute HIV infection (AHI) have heightened transmission risk. We evaluated potential transmission reduction using behavioral and biomedical interventions in a randomized controlled pilot study in Malawi. METHODS: Persons were random ... Full text Link to item Cite

Sustained Sexual Behavior Change After Acute HIV Diagnosis in Malawi.

Journal Article Sex Transm Dis · November 2018 BACKGROUND: Identification of acute HIV infection (AHI) allows for important opportunities for HIV prevention through behavior change and biomedical intervention. Here, we evaluate changes in sexual risk behaviors among persons with AHI enrolled in a combi ... Full text Link to item Cite

Leveraging Phylogenetics to Understand HIV Transmission and Partner Notification Networks.

Journal Article J Acquir Immune Defic Syndr · August 1, 2018 BACKGROUND: Partner notification is an important component of public health test and treat interventions. To enhance this essential function, we assessed the potential for molecular methods to supplement routine partner notification and corroborate HIV net ... Full text Link to item Cite

Integration of Contact Tracing and Phylogenetics in an Investigation of Acute HIV Infection.

Journal Article Sex Transm Dis · April 2018 BACKGROUND: The integration of traditional contact tracing with HIV sequence analyses offers opportunities to mitigate some of the barriers to effective network construction. We used combined analyses during an outbreak investigation of spatiotemporally cl ... Full text Link to item Cite

Incorporating Acute HIV Screening into Routine HIV Testing at Sexually Transmitted Infection Clinics, and HIV Testing and Counseling Centers in Lilongwe, Malawi.

Journal Article J Acquir Immune Defic Syndr · March 1, 2016 BACKGROUND AND OBJECTIVES: Integrating acute HIV-infection (AHI) testing into clinical settings is critical to prevent transmission, and realize potential treatment-as-prevention benefits. We evaluated acceptability of AHI testing and compared AHI prevalen ... Full text Link to item Cite

United Airway Disease Among Crop Farmers.

Journal Article J Agromedicine · 2016 Although there are observed relationships between agriculture and respiratory health problems, little attention has been given to relationship between lower and upper airway problems among farmers in the United States. The objective was to investigate the ... Full text Link to item Cite

HIV Transmission Patterns Among Immigrant Latinos Illuminated by the Integration of Phylogenetic and Migration Data.

Journal Article AIDS Res Hum Retroviruses · October 2015 Latinos represent a growing proportion of HIV cases in North Carolina (NC). Understanding how immigrants are involved in local HIV transmission is important to guide interventions. We used phylogenetics to characterize Latino involvement in local HIV trans ... Full text Link to item Cite

P1-S5.39 Triple jeopardy? Sexual networks of syphilis & HIV infection among heterosexuals, MSM, and bisexual men in North Carolina

Conference Sexually Transmitted Infections · July 2011 BackgroundThe velocity of STI spread depends in part on the formation of sexual partnerships and the structure of sexual networks. Dual outbreaks of HIV and syphilis have persisted in NC since 2001 among young bla ... Full text Cite