Overview
My primary research focus lies at the intersection of kidney and cardiovascular disease including pulmonary hypertension, heart failure, and atherosclerotic disease in patients with chronic kidney disease.
Current Appointments & Affiliations
Assistant Professor of Medicine
·
2021 - Present
Medicine, Nephrology,
Medicine
Member in the Duke Clinical Research Institute
·
2019 - Present
Duke Clinical Research Institute,
Institutes and Centers
Recent Publications
Glucarpidase for Treatment of High-Dose Methotrexate Toxicity.
Journal Article Blood · January 6, 2025 High-dose methotrexate (MTX) results in high rates of acute kidney injury (AKI), neutropenia, and hepatotoxicity. Glucarpidase is a recombinant enzyme that cleaves MTX, but clinical data supporting its use are scarce. We examined the association between gl ... Full text Link to item CiteTight Phosphate Control in ESKD Patients Is Warranted: CON.
Journal Article Kidney360 · December 13, 2024 Full text Link to item CiteKlotho and Clinical Outcomes in CKD: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study.
Journal Article Am J Kidney Dis · September 2024 RATIONALE & OBJECTIVE: Klotho deficiency may affect clinical outcomes in chronic kidney disease (CKD) through fibroblast growth factor-23 (FGF23)-dependent and -independent pathways. However, the association between circulating Klotho and clinical outcomes ... Full text Link to item CiteRecent Grants
Novel Mechanisms and Therapeutic Targets for Pulmonary Hypertension in End-Stage Renal Disease (K23)
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2021 - 2026The Role of Klotho and Serotonin in Cardiovascular Outcomes and Mortality in CKD
ResearchCo-Principal Investigator · Awarded by University of Pennsylvania · 2021 - 2024View All Grants
Education, Training & Certifications
Mercer University, School of Medicine ·
2013
M.D.