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Daniel Len Edmonston

Assistant Professor of Medicine
Medicine, Nephrology

Overview


My primary research focus lies at the intersection of kidney and cardiovascular disease including pulmonary hypertension, heart failure, and atherosclerotic disease in patients with chronic kidney disease.

Current Appointments & Affiliations


Assistant Professor of Medicine · 2021 - Present Medicine, Nephrology, Medicine
Member in the Duke Clinical Research Institute · 2019 - Present Duke Clinical Research Institute, Institutes and Centers

In the News


Published October 10, 2025
CKD in T2D: Evaluating Concordance With Screening and Treatment Guidelines
Published July 10, 2025
Few with type 2 diabetes receive guideline-recommended CKD screening
Published August 19, 2024
Both SGLT2 and GLP-1 Drugs Help Heart and Kidneys in Type 2 Diabetes

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Recent Publications


Glucarpidase for treatment of high-dose methotrexate toxicity.

Journal Article Blood · April 24, 2025 High-dose methotrexate (MTX) results in high rates of acute kidney injury (AKI), neutropenia, and hepatotoxicity. Glucarpidase is a recombinant enzyme that cleaves MTX, but clinical data supporting its use are scarce. We examined the association between gl ... Full text Link to item Cite
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Recent Grants


TRIO NRSA Training Core-Post Doc Trainee

Inst. Training Prgm or CMEMentor · Awarded by University of North Carolina - Chapel Hill · 2023 - 2028

Novel Mechanisms and Therapeutic Targets for Pulmonary Hypertension in End-Stage Renal Disease (K23)

ResearchPrincipal Investigator · Awarded by National Heart, Lung, and Blood Institute · 2021 - 2026

The Role of Klotho and Serotonin in Cardiovascular Outcomes and Mortality in CKD

ResearchCo-Principal Investigator · Awarded by University of Pennsylvania · 2021 - 2024

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Education, Training & Certifications


Mercer University, School of Medicine · 2013 M.D.