Scholars@Duke
Daniel Guidot

Daniel Guidot

Adjunct Associate in the Department of Medicine
Medicine, Pulmonary, Allergy, and Critical Care Medicine
daniel.guidot@duke.edu
300 W. Morgan Street, Durham, NC 27701

Selected Publications

Pulmonary Disease in the Older Adult: A Review of Interstitial Lung Disease.

Journal Article Clin Geriatr Med · November 2025 Interstitial lung diseases (ILDs) are a group of diverse conditions of critical importance to the care of the older adult that can cause pulmonary fibrosis, respiratory failure, and death. Aging and geriatric principles are key factors in the epidemiology, ... Full text Link to item Cite

The Epidemiology of Combined Pulmonary Fibrosis and Emphysema among Mid-Atlantic Veterans.

Journal Article Ann Am Thorac Soc · October 2025 Rationale: Combined pulmonary fibrosis and emphysema (CPFE) is a unique phenotype with important prognosis and management implications in patients with idiopathic pulmonary fibrosis (CPFE-IPF) and other forms of fibrotic interstitial lung disease (CPFE-fIL ... Full text Link to item Cite

Racial disparities in lung function by pulmonary function testing among lung transplant candidates and race-specific reference equations.

Journal Article JHLT Open · May 2025 Non-White patients with interstitial lung disease (ILD) experience racial disparities in lung transplant waitlist mortality. Race-specific equations for spirometry may contribute by underestimating restriction severity in non-White candidates. We analyzed ... Full text Link to item Cite

Polypharmacy and potentially inappropriate medication (PIM) use among older veterans with idiopathic pulmonary fibrosis (IPF) - a retrospective cohort study.

Journal Article BMC Pulm Med · April 21, 2025 BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a deadly respiratory disease of older patients. IPF therapies (antifibrotics) are efficacious in slowing disease progression, but they are critically underutilized. Potential barriers to antifibrotic use a ... Full text Link to item Cite

Comparison of race-specific and race-neutral spirometry equations on the classification of restrictive lung physiology, interstitial lung disease, and lung transplant referral eligibility.

Journal Article JHLT Open · August 2024 BACKGROUND: Race-specific reference equations for spirometry, including forced vital capacity (FVC), are under scrutiny in interstitial lung disease (ILD). Their influence on ILD and transplant decision-making warrants study. METHODS: We performed a retros ... Full text Link to item Cite

Identifying inequities in lung transplantation: a call for strategies and future research.

Journal Article JHLT Open · December 2023 Innovations in organ preservation, surgical technique, and postoperative care have transformed solid organ transplantation. As organ transplantation becomes more common, potential racial, ethnic, and socioeconomic inequities in the referral and selection p ... Full text Open Access Link to item Cite

Lung transplantation during acute exacerbations of interstitial lung disease and post-transplant survival.

Journal Article JHLT Open · December 2023 BACKGROUND: Acute exacerbations of interstitial lung disease (AE-ILD) cause severe respiratory failure, and mortality is high despite treatment. Lung transplantation is an effective therapy for late-stage interstitial lung disease (ILD), but prior studies ... Full text Link to item Cite

Surveillance imaging in mantle cell lymphoma in first remission lacks clinical utility.

Journal Article Leuk Lymphoma · April 2018 Mantle cell lymphoma (MCL) is a heterogeneous disease with high relapse rates. Limited data guide the use of surveillance imaging following treatment. We constructed a retrospective cohort from two academic institutions of patients with MCL who completed f ... Full text Link to item Cite

A vacuolar-H(+) -pyrophosphatase (TgVP1) is required for microneme secretion, host cell invasion, and extracellular survival of Toxoplasma gondii.

Journal Article Mol Microbiol · August 2014 The vacuolar proton pyrophosphatase (H(+) -PPase) of Toxoplasma gondii (TgVP1), a membrane proton pump, localizes to acidocalcisomes and a novel lysosome-like compartment termed plant-like vacuole (PLV) or vacuolar compartment (VAC). We report the characte ... Full text Link to item Cite

Chronic alcohol ingestion exacerbates skeletal muscle myopathy in HIV-1 transgenic rats.

Journal Article AIDS Res Ther · August 16, 2011 BACKGROUND: Separately, chronic alcohol ingestion and HIV-1 infection are associated with severe skeletal muscle derangements, including atrophy and wasting, weakness, and fatigue. One prospective cohort study reported that 41% of HIV-infected patients met ... Full text Link to item Cite