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Daniel Bryce Landi

Assistant Professor of Pediatrics
Pediatrics, Hematology-Oncology
Box 102382, Durham, NC 27710
330 Trent Drive, Room 390, Durham, NC 27710

Current Appointments & Affiliations


Assistant Professor of Pediatrics · 2021 - Present Pediatrics, Hematology-Oncology, Pediatrics
Member of the Duke Cancer Institute · 2023 - Present Duke Cancer Institute, Institutes and Centers

In the News


Published January 17, 2025
Randall Saladin’s Hopeful Journey at Duke Health

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Recent Publications


A Checkpoint Reversal Receptor Mediates Bipartite Activation and Enhances CAR T-cell Function.

Journal Article Cancer Res Commun · March 1, 2025 ABSTRACT: The efficacy of chimeric antigen receptor T cells (CART) in solid tumors is limited by immune inhibition. In our study, we observed that effector cytokines mediated the upregulation of the PD-L1 immune checkpoint in primary glioblastoma. To offse ... Full text Link to item Cite

Use, access, and initial outcomes of off-label ivosidenib in patients with IDH1 mutant glioma.

Journal Article Neurooncol Pract · April 2024 BACKGROUND: Isocitrate dehydrogenase (IDH) is commonly mutated (mIDH) in gliomas, and this mutant enzyme produces the oncometabolite 2-hydroxyglutarate (2HG). 2HG promotes gliomagenesis and is implicated in epileptogenesis. Ivosidenib (IVO), a small molecu ... Full text Link to item Cite
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Education, Training & Certifications


University of Colorado, School of Medicine · 2009 M.D.