Overview
Dr. Danny Benjamin is the Principal Investigator and Chair of the National Institute of Child Health and Human Development’s Pediatric Trials Network. The Network is responsible for designing and leading clinical trials of off-patent medicines in children of all ages across all therapeutic areas. The team has established, or is actively studying, the correct dosing and safety of more than 100 of the most commonly used medicines in children. These trials are conducted under an Investigational New Drug (IND) application with guidance from the Food and Drug Administration for labeling.
The Pediatric Trials Network has directly impacted the healthcare of over 90% of American children.
Signature programs of the Network include clinical trials in premature, term infants, breast feeding mothers, and obese children. Over the past 10 years, Danny’s group has enrolled more premature infants, at more sites, in more clinical trials of off-patent anti-infectives under an IND than all other academic medical centers, pharmaceutical companies, and government agencies in the world, combined.
Danny is recognized by the National Institutes of Health as a premiere mentor and educator. His research program serves as a platform to train students and early career investigators. Danny’s group has a clinical research summer program for high school, college graduate school, and medical students that recruits and mentors ~30 students each academic year. He has been the primary or secondary mentor for 10 faculty who have received career development awards and who have then gone on to establish their own independent research programs; six of whom are now Distinguished Professors.
Danny's service to the community is expressed through his passion for coaching baseball. He has coached over 1,000 recreation league, travel league, and scholastic baseball games. He is the head coach for Smith Middle School Baseball, perennially southern conference champions. Danny and his wife own a charitable non-profit that provides athletic and fitness opportunities for disadvantaged and special-needs school-aged boys and girls.
Current Appointments & Affiliations
Recent Publications
Evaluation of electronic health record to HL7® FHIR® mappings in pediatric research studies.
Journal Article Int J Med Inform · April 1, 2026 BACKGROUND: eSource technologies that exchange patient data from electronic health records (EHR) to clinical study electronic data capture (EDC) systems can reduce data quality errors and decrease data collection time. However, the availability of site-spe ... Full text Link to item CiteOpioid and sedative use in extremely preterm infants receiving mechanical ventilation.
Journal Article J Perinatol · April 2026 OBJECTIVE: Quantify opioid and sedative medication exposures in preterm infants receiving mechanical ventilation. STUDY DESIGN: Cohort study of infants <28 weeks' gestation receiving any mechanical ventilation in the first 28 postnatal days. We examined ex ... Full text Link to item CitePopulation Pharmacokinetics and Exposure-Safety Analysis of Furosemide in Preterm Infants.
Journal Article J Clin Pharmacol · April 2026 Furosemide is the most commonly used diuretic in preterm infants despite an incompletely understood relationship between dosing, exposure, and safety within this population. The goals of this study were to characterize furosemide population pharmacokinetic ... Full text Link to item CiteRecent Grants
Best Pharmaceuticals for Children Act Pediatric Trials Network
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2025 - 2032PTN 3.0 Task Order #2_ BPCA Pediatric Drug Development Clinical Trial Infrastructure
ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2025 - 2030Combating Related Epidemics in HCV through Simplified Testing and Treatment (CREST). A cluster randomized trial of point-of-care hepatitis C testing and treatment among key populations
ResearchCo Investigator · Awarded by National Institutes of Health · 2025 - 2030View All Grants