Daniel Kelly Benjamin Jr.
Kiser-Arena Professor of Pediatrics
Dr. Danny Benjamin is the Principal Investigator and Chair of the National Institute of Child Health and Human Development’s Pediatric Trials Network. The Network is responsible for designing and leading clinical trials of off-patent medicines in children of all ages across all therapeutic areas. The team has established, or is actively studying, the correct dosing and safety of more than 50 of the most commonly used medicines in children. Each of these trials is conducted under an investigational new drug (IND) application with guidance from the Food and Drug Administration for labeling.
Signature programs of the Network include clinical trials in premature, term infants and most recently, obese children. Over the past 10 years, Dr. Benjamin’s group has enrolled more premature infants, at more sites, in more clinical trials of off-patent anti-infectives under an IND than all other academic medical centers, pharmaceutical companies, and government agencies in the world, combined.
Dr. Benjamin is recognized by the National Institutes of Health as a premiere mentor and educator. His research program serves as a platform to train students and early career investigators. Dr. Benjamin’s group has a clinical research summer program for high school and college students targeting under-represented minority students, and he is the primary mentor for medical students, residents, subspecialty fellows (including two T32 programs sponsored by NIH for which he is PI), and multiple junior faculty.
Dr. Benjamin has published over 250 works with up to 7000 citations.
Current Appointments & Affiliations
- Kiser-Arena Professor of Pediatrics, Pediatrics, Infectious Diseases, Pediatrics 2014
- Professor of Pediatrics, Pediatrics, Infectious Diseases, Pediatrics 2010
- Member in the Duke Clinical Research Institute, Duke Clinical Research Institute, Institutes and Centers 2001
Contact Information
- 7044 Duke Clinical Research Institute, 2400 Pratt St, Durham, NC 27710
- Duke Box 17969, Duke Clinical Research Institute, Durham, NC 27710
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(919) 668-7081
- Background
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Education, Training, & Certifications
- Ph.D., University of North Carolina at Chapel Hill 2003
- Fellow, Pediatric Infectious Diseases, Pediatrics, Duke University 1998 - 2001
- M.P.H., University of North Carolina at Chapel Hill 2001
- Resident, Pediatrics, Children's Hospital 1995 - 1998
- M.D., University of Virginia 1995
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Duke Appointment History
- Chief, Division of Quantitative Sciences, Pediatrics, Pediatrics, Clinical Science Departments 2007 - 2010
- Associate Professor of Pediatrics, Pediatrics, Infectious Diseases, Pediatrics 2007 - 2010
- Associate Professor of Pediatrics, Pediatrics, Infectious Diseases, Pediatrics 2005 - 2007
- Assistant Professor of Pediatrics, Pediatrics, Infectious Diseases, Pediatrics 2002 - 2005
- Associate in the Department of Pediatrics, Pediatrics, Infectious Diseases, Pediatrics 2001 - 2002
- Instructor, Temporary in the Department of Pediatrics, Pediatrics, Clinical Science Departments 2001
- Recognition
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In the News
- Expertise
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Global Scholarship
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Research
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- Research
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Selected Grants
- ECHO Coordinating Center awarded by National Institutes of Health 2016 - 2023
- Center for Innovative TRIals in ChilDrEN and AdulTs (TRIDENT) awarded by National Institutes of Health 2016 - 2023
- Duke CTSA (KL2) awarded by National Institutes of Health 2018 - 2023
- Duke CTSA (TL1) awarded by National Institutes of Health 2018 - 2023
- Duke Summer Training in Academic Research (Duke's STAR) awarded by National Institutes of Health 2018 - 2023
- Global Pediatric Clinical Trials Network awarded by Food and Drug Administration 2017 - 2022
- Duke Resident Physician-Scientist Program- NIAID awarded by National Institutes of Health 2018 - 2022
- Pharmacokinetics, Pharmacodynamics, and Safety of Methylprednisolone in Neonates on Cardiopulmonary Bypass awarded by National Institutes of Health 2017 - 2022
- Duke Resident Physician-Scientist Program- NHLBI awarded by National Institutes of Health 2018 - 2022
- Bridging the Gap to Enhance Clinical Research Program (BIGGER) awarded by National Institutes of Health 2016 - 2021
- Investigating polypharmacy-related adverse events in critically ill children using electronic health records and simulated drug levels awarded by National Institutes of Health 2017 - 2021
- Mentoring Patient Oriented Research in Antibiotic-Resistant Bacteria awarded by National Institutes of Health 2011 - 2021
- Physiologically Based Pharmacokinetics in Critically Ill Children awarded by National Institutes of Health 2014 - 2019
- Mentorship of early-career pediatricians in quantitative methods and therapeutics awarded by National Institutes of Health 2018 - 2019
- UNC-Duke Collaborative Clinical Pharmacology Postdoctoral Training Program awarded by University of North Carolina - Chapel Hill 2017 - 2019
- UNC-Duke Collaborative Clinical Pharmacology Postdoctoral Training Program awarded by University of North Carolina - Chapel Hill 2016 - 2019
- Pediatric Trials Network_ Task Order 1_ Core Function Activities awarded by National Institute for Child Health & Human Develo 2018 - 2019
- SOLI - Solithromycin Pediatric Development Program (Phase 2/3)- Labor & Sub Cost awarded by Cempra Pharmaceuticals, Inc. 2016 - 2018
- Duke Research Training Program for Pediatricians awarded by National Institutes of Health 2002 - 2018
- PTN TO #34: Program Management Support - Option 2 awarded by National Institute for Child Health & Human Develo 2017 - 2018
- PTN TO #34: Program Management Support - Option 2 Mod 1 (Mod 4) awarded by National Institute for Child Health & Human Develo 2017 - 2018
- PTN TO#47 (Protocol Development V) awarded by National Institute for Child Health & Human Develo 2017 - 2018
- Duke CTSA (UL1): Statistical methods for complex data in CV disease research awarded by National Institutes of Health 2013 - 2018
- NIH Summer Research Experience Programs (R25) awarded by National Institutes of Health 2013 - 2018
- PTN TO#42 HAP - Modification #1 awarded by National Institute for Child Health & Human Develo 2016 - 2017
- PTN TO#42 HAP awarded by National Institute for Child Health & Human Develo 2015 - 2017
- Pediatric Trials Network awarded by National Institutes of Health 2010 - 2017
- PTN TO #34: Program Management Support awarded by National Institute for Child Health & Human Develo 2016 - 2017
- PTN TO#14 (Mod #3) - Efficacy of sildenafil in premature infants with Pulmonary Hypertension awarded by National Institute for Child Health & Human Develo 2015 - 2017
- NRSA Training Grant for Clinical Pharmacology - Dallefeld and Chaparro awarded by University of North Carolina - Chapel Hill 2016 - 2017
- PTN Task Order #13: Pharmacokinetics of Antistaphylococcal Antibiotics in Infants awarded by National Institutes of Health 2012 - 2017
- Institutional Training Grant in Pediatric Infectious Disease awarded by National Institutes of Health 2011 - 2016
- PTN TO#40 (Protocol Development IV) awarded by National Institute for Child Health & Human Develo 2015 - 2016
- PTN Task Order #28 Baby Tape awarded by National Institutes of Health 2014 - 2016
- PTN Task Order #9: Midazolam awarded by National Institutes of Health 2011 - 2016
- The Duke Multidisciplinary Training Program in Pediatric Lung Disease awarded by National Institutes of Health 2010 - 2016
- PTN Task Order 34 - Program Management Support awarded by National Institutes of Health 2015 - 2016
- UNC-Duke Collaborative Clinical Pharmacology Postdoctoral Training Program awarded by University of North Carolina - Chapel Hill 2011 - 2016
- Phase I CTU Task Area A: Administrative and Overal Clinical Operations Support and Concept Development awarded by National Institutes of Health 2014 - 2015
- PTN Task Order #5: Acyclovir awarded by National Institutes of Health 2011 - 2015
- PTN Task Order--Protocol Development III awarded by National Institutes of Health 2014 - 2015
- PTN Task Order #15: Fluconazole Safety Trials awarded by National Institutes of Health 2012 - 2015
- PTN Task Order #16: Pediatrix Safety Study awarded by National Institutes of Health 2012 - 2015
- Pharmacokinetics and Pharmacodynamics of Antibiotics in Premature Infants awarded by National Institutes of Health 2010 - 2015
- Multidisciplinary Neonatal Training Grant awarded by National Institutes of Health 2010 - 2015
- Institutional Training Grant in Pediatric Cardiology awarded by National Institutes of Health 2009 - 2015
- PTN Task Order #24: Protocol Development II awarded by National Institutes of Health 2013 - 2014
- PTN Task Order #14: Sildenafil study awarded by National Institutes of Health 2012 - 2014
- Prevention of Invasive Candidiasis: PK, Safety, and Neurodevelopmental Outcomes awarded by National Institutes of Health 2008 - 2014
- PTN Task Order #12 Protocol Development (RFTOPs) awarded by National Institutes of Health 2012 - 2014
- PHARMACOKINETICS OF ANTIMICROBIAL AGENTS IN HIGH RISK INFANTS awarded by National Institutes of Health 2009 - 2013
- PTN Task Order #8: TAPE awarded by National Institutes of Health 2011 - 2013
- PTN Task Order #10: Ampicillin awarded by National Institutes of Health 2011 - 2013
- PTN Task Order #11: Obesity Informatics Database awarded by National Institutes of Health 2011 - 2013
- CTSA UL awarded by National Institutes of Health 2006 - 2012
- Prevention of Invasive Candidiasis: PK, Safety, and Neurodevelopmental Outcomes awarded by Food and Drug Administration 2008 - 2012
- Complement Regulates the Humoral Response to HIV-1 awarded by National Institutes of Health 2009 - 2011
- North Carolina Collaborative PPRU Network awarded by National Institutes of Health 2004 - 2010
- Best Pharmaceutical for Children Act (BPCA): Use of Meropenem in Infants awarded by National Institutes of Health 2007 - 2010
- Early Diagnosis of Neonatal Candidiasis awarded by National Institutes of Health 2005 - 2009
- Clinical Predictors of Antiretroviral Failure awarded by National Institutes of Health 2002 - 2004
- Publications & Artistic Works
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Selected Publications
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Academic Articles
- Rivera-Chaparro, ND, Ericson, J, Wu, H, Smith, PB, Clark, RH, Benjamin, DK, Cohen-Wolkowiez, M, and Greenberg, RG. "Safety, Effectiveness and Exposure-response of Micafungin in Infants: Application of an Established Pharmacokinetics Model to Electronic Health Records." The Pediatric Infectious Disease Journal 38, no. 2 (February 2019): e26-e28. Full Text
- Greenberg, RG, Gayam, S, Savage, D, Tong, A, Gorham, D, Sholomon, A, Clark, RH, Benjamin, DK, Laughon, M, Smith, PB, and Best Pharmaceuticals for Children Act—Pediatric Trials Network Steering Committee, . "Furosemide Exposure and Prevention of Bronchopulmonary Dysplasia in Premature Infants." The Journal of Pediatrics (December 20, 2018). Full Text
- Autmizguine, J, Smith, PB, Prather, K, Bendel, C, Natarajan, G, Bidegain, M, Kaufman, DA, Burchfield, DJ, Ross, AS, Pandit, P, Schell, WA, Gao, J, Benjamin, DK, and Fluconazole Prophylaxis Study Team, . "Effect of fluconazole prophylaxis on Candida fluconazole susceptibility in premature infants." The Journal of Antimicrobial Chemotherapy 73, no. 12 (December 2018): 3482-3487. Full Text
- Puia-Dumitrescu, M, Bretzius, OM, Brown, N, Fitz-Henley, JA, Ssengonzi, R, Wechsler, CS, Gray, KD, Benjamin, DK, Smith, PB, Clark, RH, Gonzalez, D, and Hornik, CP. "Evaluation of Gentamicin Exposure in the Neonatal Intensive Care Unit and Hearing Function at Discharge." The Journal of Pediatrics 203 (December 2018): 131-136. Full Text
- Cohen-Wolkowiez, M, and Benjamin, DK. "Development of Therapeutics for Children-A Tricky Balancing Act." Jama Pediatrics (November 19, 2018). Full Text
- Gray, KD, Dudash, K, Escobar, C, Freel, C, Harrison, T, McMillan, C, Puia-Dumitrescu, M, Cotten, CM, Benjamin, R, Clark, RH, Benjamin, DK, Greenberg, RG, and Best Pharmaceuticals for Children Act–Pediatric Trials Network Steering Committee, . "Prevalence and safety of diazoxide in the neonatal intensive care unit." Journal of Perinatology : Official Journal of the California Perinatal Association 38, no. 11 (November 2018): 1496-1502. Full Text
- Ku, LC, Hornik, CP, Beechinor, RJ, Chamberlain, JM, Guptill, JT, Harper, B, Capparelli, EV, Martz, K, Anand, R, Cohen-Wolkowiez, M, Gonzalez, D, and Best Pharmaceuticals for Children Act - Pediatric Trials Network Steering Committee, . "Population Pharmacokinetics and Exploratory Exposure-Response Relationships of Diazepam in Children Treated for Status Epilepticus." Cpt: Pharmacometrics & Systems Pharmacology 7, no. 11 (November 2018): 718-727. Full Text
- Kumar, KR, Clark, DA, Kim, EM, Perry, JD, Wright, K, Thomas, SA, Thompson, EJ, Greenberg, RG, Smith, PB, Benjamin, DK, Laughon, MM, Clark, RH, and Hornik, CP. "Association of Atrial Septal Defects and Bronchopulmonary Dysplasia in Premature Infants." The Journal of Pediatrics 202 (November 2018): 56-62.e2. Full Text
- Romaine, A, Clark, RH, Davis, BR, Hendershot, K, Kite, V, Laughon, M, Updike, I, Miranda, ML, Meier, PP, Patel, AL, Smith, PB, Cotten, CM, Benjamin, DK, and Greenberg, RG. "Predictors of Prolonged Breast Milk Provision to Very Low Birth Weight Infants." The Journal of Pediatrics 202 (November 2018): 23-30.e1. Full Text
- Steinbach, WJ, Benjamin, DK, and Sleasman, JW. "Funding Pediatric Subspecialty Training: Are T32 Grants the Future?." The Journal of Pediatrics 202 (November 2018): 4-7.e1. Full Text
- Benjamin, DK, Kaufman, DA, Hope, WW, Smith, PB, Arrieta, A, Manzoni, P, Kovanda, LL, Lademacher, C, Isaacson, B, Jednachowski, D, Wu, C, Kaibara, A, and Walsh, TJ. "A Phase 3 Study of Micafungin Versus Amphotericin B Deoxycholate in Infants With Invasive Candidiasis." The Pediatric Infectious Disease Journal 37, no. 10 (October 2018): 992-998. Full Text
- Shakhnovich, V, Brian Smith, P, Guptill, JT, James, LP, Collier, DN, Wu, H, Livingston, CE, Zhao, J, Kearns, GL, Cohen-Wolkowiez, M, and Best Pharmaceuticals for Children Act–Pediatric Trials Network, . "A Population-Based Pharmacokinetic Model Approach to Pantoprazole Dosing for Obese Children and Adolescents." Paediatric Drugs 20, no. 5 (October 2018): 483-495. Full Text
- Tsakiri, S, Aneji, C, Domonoske, C, Mazur, L, Benjamin, DK, and Wootton, SH. "Voriconazole Treatment for an Infant With Intractable Candida glabrata Meningitis." The Pediatric Infectious Disease Journal 37, no. 10 (October 2018): 999-1001. Full Text
- Wang, LA, Smith, PB, Laughon, M, Goldberg, RN, Ku, LC, Zimmerman, KO, Balevic, S, Clark, RH, Benjamin, DK, Greenberg, RG, and Best Pharmaceuticals for Children Act – Pediatric Trials Network Steering Committee, . "Prolonged furosemide exposure and risk of abnormal newborn hearing screen in premature infants." Early Human Development 125 (October 2018): 26-30. Full Text
- Autmizguine, J, Tan, S, Cohen-Wolkowiez, M, Cotten, CM, Wiederhold, N, Goldberg, RN, Adams-Chapman, I, Stoll, BJ, Smith, PB, Benjamin, DK, and NICHD Neonatal Research Network, . "Antifungal Susceptibility and Clinical Outcome in Neonatal Candidiasis." The Pediatric Infectious Disease Journal 37, no. 9 (September 2018): 923-929. Full Text
- Thaden, JT, Chiswell, K, Jaffe, I, Bergin, SP, Yang, WE, Romaine, A, Roberts, J, Nambiar, S, Farley, J, Benjamin, DK, Smith, PB, and Tsalik, EL. "Pediatric Antibacterial and Antifungal Trials From 2007 to 2017." Pediatrics 142, no. 3 (September 2018). Full Text
- Ariagno, RL, Lee, HC, Stevenson, DK, Benjamin, DK, Smith, PB, Escobedo, MB, and Bhatt, DR. "A directory for neonatal intensive care: potential for facilitating network-based research in neonatology." Journal of Perinatology : Official Journal of the California Perinatal Association 38, no. 8 (August 2018): 954-958. Full Text
- Gonzalez, D, James, LP, Al-Uzri, A, Bosheva, M, Adler-Shohet, FC, Mendley, SR, Bradley, JS, Espinosa, C, Tsonkova, E, Moffett, K, Marquez, L, Simonsen, KA, Stoilov, S, Boakye-Agyeman, F, Jasion, T, Hornik, CP, Hernandez, R, Benjamin, DK, and Cohen-Wolkowiez, M. "Population Pharmacokinetics and Safety of Solithromycin following Intravenous and Oral Administration in Infants, Children, and Adolescents." Antimicrobial Agents and Chemotherapy 62, no. 8 (August 2018). Full Text
- Gonzalez, D, James, LP, Al-Uzri, A, Bosheva, M, Adler-Shohet, FC, Mendley, SR, Bradley, JS, Espinosa, C, Tsonkova, E, Moffett, K, Marquez, L, Simonsen, KA, Stoilov, S, Boakye-Agyeman, F, Jasion, T, Hornik, CP, Hernandez, R, Benjamin, DK, and Cohen-Wolkowiez, M. "Population Pharmacokinetics and Safety of Solithromycin following Intravenous and Oral Administration in Infants, Children, and Adolescents." Antimicrobial Agents and Chemotherapy 62, no. 8 (August 1, 2018). (Academic Article) Full Text Link to Item
- Kovanda, LL, Walsh, TJ, Benjamin, DK, Arrieta, A, Kaufman, DA, Smith, PB, Manzoni, P, Desai, AV, Kaibara, A, Bonate, PL, and Hope, WW. "Exposure-Response Analysis of Micafungin in Neonatal Candidiasis: Pooled Analysis of Two Clinical Trials." The Pediatric Infectious Disease Journal 37, no. 6 (June 2018): 580-585. Full Text
- Smith, B, Knox, S, and Benjamin, DK. "Coordination of the Environmental influences on Child Health Outcomes program: so the whole is greater than the sum of its parts." Current Opinion in Pediatrics 30, no. 2 (April 2018): 263-268. (Review) Full Text
- Corneli, A, Wheeler, C, Bradley, J, Gamel, B, Nambiar, S, Noel, GJ, Lin, L, Roberts, JN, and Benjamin, DK. "Facilitators and barriers to the successful implementation of pediatric antibacterial drug trials: Findings from CTTI's survey of investigators." Contemporary Clinical Trials Communications 9 (March 2018): 115-120. Full Text
- Greenberg, RG, Corneli, A, Bradley, J, Farley, J, Jafri, HS, Lin, L, Nambiar, S, Noel, GJ, Wheeler, C, Tiernan, R, Smith, PB, Roberts, J, and Benjamin, DK. "Perceived barriers to pediatrician and family practitioner participation in pediatric clinical trials: Findings from the Clinical Trials Transformation Initiative." Contemporary Clinical Trials Communications 9 (March 2018): 7-12. Full Text
- Greenberg, RG, Gamel, B, Bloom, D, Bradley, J, Jafri, HS, Hinton, D, Nambiar, S, Wheeler, C, Tiernan, R, Smith, PB, Roberts, J, and Benjamin, DK. "Parents' perceived obstacles to pediatric clinical trial participation: Findings from the clinical trials transformation initiative." Contemporary clinical trials communications 9 (March 2018): 33-39. Full Text
- Le, J, Poindexter, B, Sullivan, JE, Laughon, M, Delmore, P, Blackford, M, Yogev, R, James, LP, Melloni, C, Harper, B, Mitchell, J, Benjamin, DK, Boakye-Agyeman, F, and Cohen-Wolkowiez, M. "Comparative Analysis of Ampicillin Plasma and Dried Blood Spot Pharmacokinetics in Neonates." Therapeutic Drug Monitoring 40, no. 1 (February 2018): 103-108. Full Text
- Shakhnovich, V, Smith, PB, Guptill, JT, James, LP, Collier, DN, Wu, H, Livingston, CE, Zhao, J, Kearns, GL, and Best Pharmaceuticals for Children Act – Pediatric Trials Network, . "Obese Children Require Lower Doses of Pantoprazole Than Nonobese Peers to Achieve Equal Systemic Drug Exposures." The Journal of Pediatrics 193 (February 2018): 102-108.e1. Full Text
- Testoni, D, Hornik, CP, Guinsburg, R, Clark, RH, Greenberg, RG, Benjamin, DK, and Smith, PB. "Early lumbar puncture and risk of intraventricular hemorrhage in very low birth weight infants." Early Human Development 117 (February 2018): 1-6. Full Text
- Ward, RM, Benjamin, DK, Davis, JM, Gorman, RL, Kauffman, R, Kearns, GL, Murphy, MD, and Sherwin, CMT. "The Need for Pediatric Drug Development." The Journal of Pediatrics 192 (January 2018): 13-21. Full Text
- Watt, KM, Avant, D, Sherwin, J, Benjamin, DK, Hornik, C, Li, JS, and Smith, PB. "Effect of renal function on antihypertensive drug safety and efficacy in children." Pediatric Nephrology (Berlin, Germany) 33, no. 1 (January 2018): 139-146. Full Text
- Hwang, MF, Beechinor, RJ, Wade, KC, Benjamin, DK, Smith, PB, Hornik, CP, Capparelli, EV, Duara, S, Kennedy, KA, Cohen-Wolkowiez, M, and Gonzalez, D. "External Evaluation of Two Fluconazole Infant Population Pharmacokinetic Models." Antimicrobial Agents and Chemotherapy 61, no. 12 (December 2017). Full Text
- Watt, KM, Cohen-Wolkowiez, M, Williams, DC, Bonadonna, DK, Cheifetz, IM, Thakker, D, Benjamin, DK, and Brouwer, KLR. "Antifungal Extraction by the Extracorporeal Membrane Oxygenation Circuit." The Journal of Extra Corporeal Technology 49, no. 3 (September 2017): 150-159.
- Gonzalez, D, Chamberlain, JM, Guptill, JT, Cohen-Wolkowiez, M, Harper, B, Zhao, J, Capparelli, EV, and Best Pharmaceuticals for Children Act – Pediatric Trials Network Steering Committee, . "Population Pharmacokinetics and Exploratory Pharmacodynamics of Lorazepam in Pediatric Status Epilepticus." Clinical Pharmacokinetics 56, no. 8 (August 2017): 941-951. Full Text
- Wynn, JL, Kelly, MS, Benjamin, DK, Clark, RH, Greenberg, R, Benjamin, DK, and Smith, PB. "Timing of Multiorgan Dysfunction among Hospitalized Infants with Fatal Fulminant Sepsis." American journal of perinatology 34, no. 7 (June 2017): 633-639. Full Text
- Ericson, JE, Gostelow, M, Autmizguine, J, Hornik, CP, Clark, RH, Benjamin, DK, Smith, PB, and Pediatric Trials Network Executive Committee and Investigators, . "Safety of High-dose Acyclovir in Infants With Suspected and Confirmed Neonatal Herpes Simplex Virus Infections." The Pediatric Infectious Disease Journal 36, no. 4 (April 2017): 369-373. Full Text
- Lee, JA, Sauer, B, Tuminski, W, Cheong, J, Fitz-Henley, J, Mayers, M, Ezuma-Igwe, C, Arnold, C, Hornik, CP, Clark, RH, Benjamin, DK, Smith, PB, Ericson, JE, and Best Pharmaceuticals for Children Act—Pediatric Trials Network Steering Committee, . "Effectiveness of Granulocyte Colony-Stimulating Factor in Hospitalized Infants with Neutropenia." American Journal of Perinatology 34, no. 5 (April 2017): 458-464. Full Text
- Smith, MJ, Gonzalez, D, Goldman, JL, Yogev, R, Sullivan, JE, Reed, MD, Anand, R, Martz, K, Berezny, K, Benjamin, DK, Smith, PB, Cohen-Wolkowiez, M, Watt, K, and Best Pharmaceuticals for Children Act—Pediatric Trials Network Steering Committee, . "Pharmacokinetics of Clindamycin in Obese and Nonobese Children." Antimicrobial Agents and Chemotherapy 61, no. 4 (April 2017). Full Text
- Mankouski, A, Kantores, C, Wong, MJ, Ivanovska, J, Jain, A, Benner, EJ, Mason, SN, Tanswell, AK, Auten, RL, and Jankov, RP. "Intermittent hypoxia during recovery from neonatal hyperoxic lung injury causes long-term impairment of alveolar development: A new rat model of BPD." American Journal of Physiology. Lung Cellular and Molecular Physiology 312, no. 2 (February 2017): L208-L216. Full Text
- Parente, V, Clark, RH, Ku, L, Fennell, C, Johnson, M, Morris, E, Romaine, A, Utin, U, Benjamin, DK, Messina, JA, Smith, PB, and Greenberg, RG. "Risk factors for group B streptococcal disease in neonates of mothers with negative antenatal testing." Journal of Perinatology : Official Journal of the California Perinatal Association 37, no. 2 (February 2017): 157-161. Full Text
- Wang, LA, Gonzalez, D, Leeder, JS, Tyndale, RF, Pearce, RE, Benjamin, DK, Kearns, GL, Cohen-Wolkowiez, M, and Best Pharmaceuticals for Children Act-Pediatric Trials Network Steering Committee, . "Metronidazole Metabolism in Neonates and the Interplay Between Ontogeny and Genetic Variation." Journal of Clinical Pharmacology 57, no. 2 (February 2017): 230-234. Full Text
- Zhang, CJ, Bidlingmaier, M, Altaye, M, Page, LC, D'Alessio, D, Tschöp, MH, and Tong, J. "Acute administration of acyl, but not desacyl ghrelin, decreases blood pressure in healthy humans." European Journal of Endocrinology 176, no. 2 (February 2017): 123-132. Full Text
- Lloyd, JC, Hornik, CP, Benjamin, DK, Clark, RH, Routh, JC, and Smith, PB. "Incidence of Breakthrough Urinary Tract Infection in Hospitalized Infants Receiving Antibiotic Prophylaxis." Clinical Pediatrics 56, no. 1 (January 2017): 65-70. Full Text
- Smith, PB, Benjamin, DK, and Reed, AM. "The Role of a Division of Quantitative Sciences Division in Enhancing Academic Productivity of a Department of Pediatrics." The Journal of Pediatrics 180 (January 2017): 4-5. Full Text
- Autmizguine, J, Hornik, CP, Benjamin, DK, Brouwer, KLR, Hupp, SR, Cohen-Wolkowiez, M, and Watt, KM. "Pharmacokinetics and Safety of Micafungin in Infants Supported With Extracorporeal Membrane Oxygenation." The Pediatric infectious disease journal 35, no. 11 (November 2016): 1204-1210. Full Text
- Autmizguine, J, Hornik, CP, Jr, BDK, Brouwer, KLR, Hupp, SR, Cohen-Wolkowiez, M, and Watt, KM. "Pharmacokinetics and Safety of Micafungin in Infants Supported With Extracorporeal Membrane Oxygenation." PEDIATRIC INFECTIOUS DISEASE JOURNAL 35, no. 11 (November 2016): 1204-1210. Full Text Link to Item
- Hornik, CP, Benjamin, DK, Smith, PB, Pencina, MJ, Tremoulet, AH, Capparelli, EV, Ericson, JE, Clark, RH, Cohen-Wolkowiez, M, and Best Pharmaceuticals for Children Act—Pediatric Trials Network, . "Electronic Health Records and Pharmacokinetic Modeling to Assess the Relationship between Ampicillin Exposure and Seizure Risk in Neonates." The Journal of Pediatrics 178 (November 2016): 125-129.e1. Full Text
- Ericson, JE, Kaufman, DA, Kicklighter, SD, Bhatia, J, Testoni, D, Gao, J, Smith, PB, Prather, KO, Benjamin, DK, Fluconazole Prophylaxis Study Team on behalf of the Best Pharmaceuticals for Children Act–Pediatric Trials Network Steering Committeea, , and Fluconazole Prophylaxis Study Team on behalf of the Best Pharmaceuticals for Children Act–Pediatric Trials Network Steering Committee, . "Fluconazole Prophylaxis for the Prevention of Candidiasis in Premature Infants: A Meta-analysis Using Patient-level Data." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America 63, no. 5 (September 2016): 604-610. Full Text
- Folgori, L, Bielicki, J, Ruiz, B, Turner, MA, Bradley, JS, Benjamin, DK, Zaoutis, TE, Lutsar, I, Giaquinto, C, Rossi, P, and Sharland, M. "Harmonisation in study design and outcomes in paediatric antibiotic clinical trials: a systematic review." The Lancet. Infectious Diseases 16, no. 9 (September 2016): e178-e189. (Review) Full Text
- Momper, JD, Capparelli, EV, Wade, KC, Kantak, A, Dhanireddy, R, Cummings, JJ, Nedrelow, JH, Hudak, ML, Mundakel, GT, Natarajan, G, Gao, J, Laughon, M, Smith, PB, and Benjamin, DK. "Population Pharmacokinetics of Fluconazole in Premature Infants with Birth Weights Less than 750 Grams." Antimicrobial agents and chemotherapy 60, no. 9 (September 2016): 5539-5545. Full Text
- Zimmerman, K, Putera, M, Hornik, CP, Brian Smith, P, Benjamin, DK, Mulugeta, Y, Burckart, GJ, Cohen-Wolkowiez, M, and Gonzalez, D. "Exposure Matching of Pediatric Anti-infective Drugs: Review of Drugs Submitted to the Food and Drug Administration for Pediatric Approval." Clinical therapeutics 38, no. 9 (September 2016): 1995-2005. (Review) Full Text
- Romaine, A, Ye, D, Ao, Z, Fang, F, Johnson, O, Blake, T, Benjamin, DK, Cotten, CM, Testoni, D, Clark, RH, Chu, VH, Smith, PB, Hornik, CP, and Best Pharmaceuticals for Children Act – Pediatric Trials Network, . "Safety of histamine-2 receptor blockers in hospitalized VLBW infants." Early Human Development 99 (August 2016): 27-30. Full Text
- Gonzalez, D, Delmore, P, Bloom, BT, Cotten, CM, Poindexter, BB, McGowan, E, Shattuck, K, Bradford, KK, Smith, PB, Cohen-Wolkowiez, M, Morris, M, Yin, W, Benjamin, DK, and Laughon, MM. "Clindamycin Pharmacokinetics and Safety in Preterm and Term Infants." Antimicrobial Agents and Chemotherapy 60, no. 5 (May 2016): 2888-2894. Full Text
- Gonzalez, D, Palazzi, DL, Bhattacharya-Mithal, L, Al-Uzri, A, James, LP, Bradley, J, Neu, N, Jasion, T, Hornik, CP, Smith, PB, Benjamin, DK, Keedy, K, Fernandes, P, and Cohen-Wolkowiez, M. "Solithromycin Pharmacokinetics in Plasma and Dried Blood Spots and Safety in Adolescents." Antimicrobial Agents and Chemotherapy 60, no. 4 (April 2016): 2572-2576. Full Text
- Kelly, MS, Benjamin, DK, Puopolo, KM, Laughon, MM, Clark, RH, Mukhopadhyay, S, Benjamin, DK, Smith, PB, and Permar, SR. "Postnatal Cytomegalovirus Infection and the Risk for Bronchopulmonary Dysplasia." JAMA pediatrics 169, no. 12 (December 7, 2015): e153785-. Full Text
- Ericson, JE, Popoola, VO, Smith, PB, Benjamin, DK, Fowler, VG, Clark, RH, and Milstone, AM. "Burden of Invasive Staphylococcus aureus Infections in Hospitalized Infants." Jama Pediatrics 169, no. 12 (December 2015): 1105-1111. Full Text
- Thaden, JT, Ericson, JE, Cross, H, Bergin, SP, Messina, JA, Fowler, VG, Benjamin, DK, Clark, RH, Hornik, CP, Smith, PB, and Antibacterial Resistance Leadership Group, . "Survival Benefit of Empirical Therapy for Staphylococcus aureus Bloodstream Infections in Infants." The Pediatric Infectious Disease Journal 34, no. 11 (November 2015): 1175-1179. Full Text
- Arnold, CJ, Ericson, J, Cho, N, Tian, J, Wilson, S, Chu, VH, Hornik, CP, Clark, RH, Benjamin, DK, Smith, PB, and Best Pharmaceuticals for Children Act--Pediatric Trials Network Administrative Core Committee, . "Cefepime and Ceftazidime Safety in Hospitalized Infants." The Pediatric Infectious Disease Journal 34, no. 9 (September 2015): 964-968. Full Text
- Bergin, SP, Thaden, JT, Ericson, JE, Cross, H, Messina, J, Clark, RH, Fowler, VG, Benjamin, DK, Hornik, CP, Smith, PB, and Antibacterial Resistance Leadership Group, . "Neonatal Escherichia coli Bloodstream Infections: Clinical Outcomes and Impact of Initial Antibiotic Therapy." The Pediatric Infectious Disease Journal 34, no. 9 (September 2015): 933-936. Full Text
- Ericson, JE, Arnold, C, Cheeseman, J, Cho, J, Kaneko, S, Wilson, E, Clark, RH, Benjamin, DK, Chu, V, Smith, PB, Hornik, CP, and Best Pharmaceuticals for Children Act–Pediatric Trials Network Administrative Core Committee, . "Use and Safety of Erythromycin and Metoclopramide in Hospitalized Infants." Journal of Pediatric Gastroenterology and Nutrition 61, no. 3 (September 2015): 334-339. Full Text
- Offringa, M, Davis, JM, Turner, MA, Ward, R, Bax, R, Maldonado, S, Sinha, V, McCune, SK, Zajicek, A, Benjamin, DK, Bucci-Rechtweg, C, and Nelson, RM. "Applying Regulatory Science to Develop Safe and Effective Medicines for Neonates: Report of the US Food and Drug Administration First Annual Neonatal Scientific Workshop, October 28-29, 2014." Therapeutic Innovation & Regulatory Science 49, no. 5 (September 2015): 623-631. Full Text
- Rowe, S, Siegel, D, Benjamin, DK, and Best Pharmaceuticals for Children Act – Pediatric Trials Network Administrative Core Committee, . "Gaps in Drug Dosing for Obese Children: A Systematic Review of Commonly Prescribed Emergency Care Medications." Clinical therapeutics 37, no. 9 (September 2015): 1924-1932. (Review) Full Text
- Harskamp-van Ginkel, MW, Hill, KD, Becker, KC, Testoni, D, Cohen-Wolkowiez, M, Gonzalez, D, Barrett, JS, Benjamin, DK, Siegel, DA, Banks, P, Watt, KM, and Best Pharmaceuticals for Children Act–Pediatric Trials Network Administrative Core Committee, . "Drug Dosing and Pharmacokinetics in Children With Obesity: A Systematic Review." Jama Pediatrics 169, no. 7 (July 2015): 678-685. (Review) Full Text
- Watt, KM, Gonzalez, D, Benjamin, DK, Brouwer, KLR, Wade, KC, Capparelli, E, Barrett, J, and Cohen-Wolkowiez, M. "Fluconazole population pharmacokinetics and dosing for prevention and treatment of invasive Candidiasis in children supported with extracorporeal membrane oxygenation." Antimicrobial Agents and Chemotherapy 59, no. 7 (July 2015): 3935-3943. Full Text
- Arnold, CJ, Ericson, J, Kohman, J, Corey, KL, Oh, M, Onabanjo, J, Hornik, CP, Clark, RH, Benjamin, DK, Smith, PB, Chu, VH, and Best Pharmaceuticals for Children Act–Pediatric Trials Network Administrative Core Committee, . "Rifampin use and safety in hospitalized infants." American journal of perinatology 32, no. 6 (May 2015): 565-570. Full Text
- Botero-Calderon, L, Benjamin, DK, and Cohen-Wolkowiez, M. "Advances in the treatment of invasive neonatal candidiasis." Expert Opinion on Pharmacotherapy 16, no. 7 (May 2015): 1035-1048. (Review) Full Text
- Camelo Castillo, W, Boggess, K, Stürmer, T, Brookhart, MA, Benjamin, DK, and Jonsson Funk, M. "Association of Adverse Pregnancy Outcomes With Glyburide vs Insulin in Women With Gestational Diabetes." Jama Pediatrics 169, no. 5 (May 2015): 452-458. Full Text
- Ericson, JE, Thaden, J, Cross, HR, Clark, RH, Fowler, VG, Benjamin, DK, Cohen-Wolkowiez, M, Hornik, CP, Smith, PB, and Antibacterial Resistance Leadership Group, . "No survival benefit with empirical vancomycin therapy for coagulase-negative staphylococcal bloodstream infections in infants." The Pediatric Infectious Disease Journal 34, no. 4 (April 2015): 371-375. Full Text
- Johnson, JN, Hornik, CP, Li, JS, Benjamin, DK, Yoshizumi, T, Reiman, RE, Frush, DP, and Hill, KD. "Response to letters regarding article, "Cumulative radiation exposure and cancer risk estimation in children with heart disease"." Circulation 131, no. 16 (April 2015): e419-e420. (Letter) Full Text
- Kelly, MS, Benjamin, DK, and Smith, PB. "The epidemiology and diagnosis of invasive candidiasis among premature infants." Clinics in Perinatology 42, no. 1 (March 2015): 105-ix. (Review) Full Text
- Smith, PB, and Benjamin, DK. "Neonatal-perinatal infections: an update." Clinics in Perinatology 42, no. 1 (March 2015): xix-xx. Full Text
- Hope, WW, Kaibara, A, Roy, M, Arrieta, A, Azie, N, Kovanda, LL, and Benjamin, DK. "Population pharmacokinetics of micafungin and its metabolites M1 and M5 in children and adolescents." Antimicrobial Agents and Chemotherapy 59, no. 2 (February 2015): 905-913. Full Text
- Autmizguine, J, Hornik, CP, Benjamin, DK, Laughon, MM, Clark, RH, Cotten, CM, Cohen-Wolkowiez, M, Smith, PB, and Best Pharmaceuticals for Children Act—Pediatric Trials Network Administrative Core Committee, . "Anaerobic antimicrobial therapy after necrotizing enterocolitis in VLBW infants." Pediatrics 135, no. 1 (January 2015): e117-e125. Full Text
- Gonzalez, D, Melloni, C, Poindexter, BB, Yogev, R, Atz, AM, Sullivan, JE, Mendley, SR, Delmore, P, Delinsky, A, Zimmerman, K, Lewandowski, A, Harper, B, Lewis, KC, Benjamin, DK, Cohen-Wolkowiez, M, and Best Pharmaceuticals for Children Act--Pediatric Trials Network Administrative Core Committee, . "Simultaneous determination of trimethoprim and sulfamethoxazole in dried plasma and urine spots." Bioanalysis 7, no. 9 (January 2015): 1137-1149. Full Text
- Samiee-Zafarghandy, S, Raman, SR, van den Anker, JN, McHutchison, K, Hornik, CP, Clark, RH, Brian Smith, P, and Best Pharmaceuticals for Children Act—Pediatric Trials Network Administrative Core Committee, . "Safety of milrinone use in neonatal intensive care units." Early Human Development 91, no. 1 (January 2015): 31-35. Full Text
- Cohen-Wolkowiez, M, and Benjamin, DK. "Editorial commentary: Fluconazole therapeutic drug monitoring in children with cancer: not today." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America 59, no. 11 (December 2014): 1534-1536. Full Text
- Greenberg, RG, and Benjamin, DK. "Neonatal candidiasis: diagnosis, prevention, and treatment." The Journal of infection 69 Suppl 1 (November 2014): S19-S22. (Review) Full Text
- Zhao, W, Le Guellec, C, Benjamin, DK, Hope, WW, Bourgeois, T, Watt, KM, van den Anker, JN, Matrot, B, Saxen, H, Hoppu, K, Manzoni, P, and Jacqz-Aigrain, E. "First dose in neonates: are juvenile mice, adults and in vitro-in silico data predictive of neonatal pharmacokinetics of fluconazole." Clinical Pharmacokinetics 53, no. 11 (November 2014): 1005-1018. Full Text
- Autmizguine, J, Moran, C, Gonzalez, D, Capparelli, EV, Smith, PB, Grant, GA, Benjamin, DK, Cohen-Wolkowiez, M, and Watt, KM. "Vancomycin cerebrospinal fluid pharmacokinetics in children with cerebral ventricular shunt infections." The Pediatric Infectious Disease Journal 33, no. 10 (October 2014): e270-e272. Full Text
- Benjamin, DK. "Career Profile." CLINICAL PHARMACOLOGY & THERAPEUTICS 96, no. 4 (October 2014): 411-411. Link to Item
- Gonzalez, D, Melloni, C, Yogev, R, Poindexter, BB, Mendley, SR, Delmore, P, Sullivan, JE, Autmizguine, J, Lewandowski, A, Harper, B, Watt, KM, Lewis, KC, Capparelli, EV, Benjamin, DK, Cohen-Wolkowiez, M, and Best Pharmaceuticals for Children Act – Pediatric Trials Network Administrative Core Committee, . "Use of opportunistic clinical data and a population pharmacokinetic model to support dosing of clindamycin for premature infants to adolescents." Clinical Pharmacology and Therapeutics 96, no. 4 (October 2014): 429-437. Full Text
- Hsieh, EM, Hornik, CP, Clark, RH, Laughon, MM, Benjamin, DK, Smith, PB, and Best Pharmaceuticals for Children Act—Pediatric Trials Network, . "Medication use in the neonatal intensive care unit." American Journal of Perinatology 31, no. 9 (October 2014): 811-821. Full Text
- Testoni, D, Hayashi, M, Cohen-Wolkowiez, M, Benjamin, DK, Lopes, RD, Clark, RH, and Smith, PB. "Late-onset bloodstream infections in hospitalized term infants." The Pediatric Infectious Disease Journal 33, no. 9 (September 2014): 920-923. Full Text
- Gonzalez, D, Paul, IM, Benjamin, DK, and Cohen-Wolkowiez, M. "Advances in pediatric pharmacology, therapeutics, and toxicology." Advances in pediatrics 61, no. 1 (August 2014): 7-31. (Review) Full Text
- Laughon, MM, and Benjamin, DK. "Mechanisms to provide safe and effective drugs for children." Pediatrics 134, no. 2 (August 2014): e562-e563. Full Text
- Johnson, JN, Hornik, CP, Li, JS, Benjamin, DK, Yoshizumi, TT, Reiman, RE, Frush, DP, and Hill, KD. "Cumulative radiation exposure and cancer risk estimation in children with heart disease." Circulation 130, no. 2 (July 2014): 161-167. Full Text
- Autmizguine, J, Guptill, JT, Cohen-Wolkowiez, M, Benjamin, DK, and Capparelli, EV. "Pharmacokinetics and pharmacodynamics of antifungals in children: clinical implications." Drugs 74, no. 8 (June 2014): 891-909. (Review) Full Text
- Camelo Castillo, W, Boggess, K, Stürmer, T, Brookhart, MA, Benjamin, DK, and Jonsson Funk, M. "Trends in glyburide compared with insulin use for gestational diabetes treatment in the United States, 2000-2011." Obstetrics and Gynecology 123, no. 6 (June 2014): 1177-1184. Full Text
- Tremoulet, A, Le, J, Poindexter, B, Sullivan, JE, Laughon, M, Delmore, P, Salgado, A, Ian-U Chong, S, Melloni, C, Gao, J, Benjamin, DK, Capparelli, EV, Cohen-Wolkowiez, M, and Administrative Core Committee of the Best Pharmaceuticals for Children Act-Pediatric Trials Network, . "Characterization of the population pharmacokinetics of ampicillin in neonates using an opportunistic study design." Antimicrobial Agents and Chemotherapy 58, no. 6 (June 2014): 3013-3020. Full Text
- Benjamin, DK, Hudak, ML, Duara, S, Randolph, DA, Bidegain, M, Mundakel, GT, Natarajan, G, Burchfield, DJ, White, RD, Shattuck, KE, Neu, N, Bendel, CM, Kim, MR, Finer, NN, Stewart, DL, Arrieta, AC, Wade, KC, Kaufman, DA, Manzoni, P, Prather, KO, Testoni, D, Berezny, KY, Smith, PB, and Fluconazole Prophylaxis Study Team, . "Effect of fluconazole prophylaxis on candidiasis and mortality in premature infants: a randomized clinical trial." Jama 311, no. 17 (May 2014): 1742-1749. Full Text
- Cohen-Wolkowiez, M, Watt, KM, Zhou, C, Bloom, BT, Poindexter, B, Castro, L, Gao, J, Capparelli, EV, Benjamin, DK, and Smith, PB. "Developmental pharmacokinetics of piperacillin and tazobactam using plasma and dried blood spots from infants." Antimicrobial Agents and Chemotherapy 58, no. 5 (May 2014): 2856-2865. Full Text
- Bain, J, Benjamin, DK, Hornik, CP, Benjamin, DK, Clark, R, and Smith, PB. "Risk of necrotizing enterocolitis in very-low-birth-weight infants with isolated atrial and ventricular septal defects." Journal of perinatology : official journal of the California Perinatal Association 34, no. 4 (April 2014): 319-321. Full Text
- Beam, KS, Laughon, MM, Hornik, CP, Cohen-Wolkowiez, M, Clark, RH, Benjamin, DK, and Smith, PB. "Predictors of positive cerebrospinal fluid cultures in infants with bacteremia." The Pediatric Infectious Disease Journal 33, no. 4 (April 2014): 360-365. Full Text
- Ericson, JE, and Benjamin, DK. "Fluconazole prophylaxis for prevention of invasive candidiasis in infants." Current Opinion in Pediatrics 26, no. 2 (April 2014): 151-156. (Review) Full Text
- Aliaga, S, Clark, RH, Laughon, M, Walsh, TJ, Hope, WW, Benjamin, DK, Kaufman, D, Arrieta, A, and Smith, PB. "Changes in the incidence of candidiasis in neonatal intensive care units." Pediatrics 133, no. 2 (February 2014): 236-242. Full Text
- Autmizguine, J, Benjamin, DK, Smith, PB, Sampson, M, Ovetchkine, P, Cohen-Wolkowiez, M, and Watt, KM. "Pharmacokinetic studies in infants using minimal-risk study designs." Current clinical pharmacology 9, no. 4 (January 2014): 350-358. (Review) Full Text
- Sampson, MR, Bloom, BT, Arrieta, A, Capparelli, E, Benjamin, DK, Smith, PB, Kearns, GL, van den Anker, J, and Cohen-Wolkowiez, M. "Intestinal fatty-acid binding protein and metronidazole response in premature infants." Journal of Neonatal Perinatal Medicine 7, no. 3 (January 2014): 223-228. Full Text
- Tunks, RD, Barker, PCA, Benjamin, DK, Cohen-Wolkowiez, M, Fleming, GA, Laughon, M, Li, JS, and Hill, KD. "Sildenafil exposure and hemodynamic effect after Fontan surgery." Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 15, no. 1 (January 2014): 28-34. Full Text
- Benjamin, DK, Deville, JG, Azie, N, Kovanda, L, Roy, M, Wu, C, and Arrieta, A. "Safety and pharmacokinetic profiles of repeated-dose micafungin in children and adolescents treated for invasive candidiasis." The Pediatric Infectious Disease Journal 32, no. 11 (November 2013): e419-e425. Full Text
- Adams-Chapman, I, Bann, CM, Das, A, Goldberg, RN, Stoll, BJ, Walsh, MC, Sánchez, PJ, Higgins, RD, Shankaran, S, Watterberg, KL, Duara, S, Miller, NA, Heyne, RJ, Peralta-Carcelen, M, Goldstein, RF, Steichen, JJ, Bauer, CR, Hintz, SR, Evans, PW, Acarregui, MJ, Myers, GJ, Vohr, BR, Wilson-Costello, DE, Pappas, A, Vaucher, YE, Ehrenkranz, RA, McGowan, EC, Dillard, RG, Fuller, J, Benjamin, DK, and Eunice Kennedy Shriver National Institutes of Child Health and Human Development Neonatal Research Network, . "Neurodevelopmental outcome of extremely low birth weight infants with Candida infection." The Journal of Pediatrics 163, no. 4 (October 2013): 961-7.e3. Full Text
- Castillo, WC, Boggess, K, Sturmer, T, Brookhart, MA, and Jr, BDK. "Use of Glyburide vs. Insulin for Treatment of Gestational Diabetes in the US, 2000-2010." PHARMACOEPIDEMIOLOGY AND DRUG SAFETY 22 (October 2013): 145-145. Link to Item
- Sampson, MR, Bloom, BT, Lenfestey, RW, Harper, B, Kashuba, AD, Anand, R, Benjamin, DK, Capparelli, E, Cohen-Wolkowiez, M, and Smith, PB. "Population Pharmacokinetics of Intravenous Acyclovir in Preterm and Term Infants." Pediatr Infect Dis J (September 23, 2013). Full Text Link to Item
- Cohen-Wolkowiez, M, Sampson, M, Bloom, BT, Arrieta, A, Wynn, JL, Martz, K, Harper, B, Kearns, GL, Capparelli, EV, Siegel, D, Benjamin, DK, Smith, PB, and Best Pharmaceuticals for Children Act–Pediatric Trials Network, . "Determining population and developmental pharmacokinetics of metronidazole using plasma and dried blood spot samples from premature infants." The Pediatric Infectious Disease Journal 32, no. 9 (September 2013): 956-961. Full Text
- Hill, KD, Tunks, RD, Barker, PCA, Benjamin, DK, Cohen-Wolkowiez, M, Fleming, GA, Laughon, M, and Li, JS. "Sildenafil exposure and hemodynamic effect after stage II single-ventricle surgery." Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 14, no. 6 (July 2013): 593-600. Full Text
- Hornik, CP, Herring, AH, Benjamin, DK, Capparelli, EV, Kearns, GL, van den Anker, J, Cohen-Wolkowiez, M, Clark, RH, Smith, PB, and Best Pharmaceuticals for Children Act-Pediatric Trials Network, . "Adverse events associated with meropenem versus imipenem/cilastatin therapy in a large retrospective cohort of hospitalized infants." The Pediatric Infectious Disease Journal 32, no. 7 (July 2013): 748-753. Full Text
- Boucher, HW, Talbot, GH, Benjamin, DK, Bradley, J, Guidos, RJ, Jones, RN, Murray, BE, Bonomo, RA, Gilbert, D, and Infectious Diseases Society of America, . "10 x '20 Progress--development of new drugs active against gram-negative bacilli: an update from the Infectious Diseases Society of America." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America 56, no. 12 (June 2013): 1685-1694. Full Text
- Ericson, J, Manzoni, P, and Benjamin, DK. "Old and new: appropriate dosing for neonatal antifungal drugs in the nursery." Early Human Development 89 Suppl 1 (June 2013): S25-S27. (Review) Full Text
- Lestner, JM, Smith, PB, Cohen-Wolkowiez, M, Benjamin, DK, and Hope, WW. "Antifungal agents and therapy for infants and children with invasive fungal infections: a pharmacological perspective." British Journal of Clinical Pharmacology 75, no. 6 (June 2013): 1381-1395. (Review) Full Text
- Picone, S, Manzoni, P, Bedetta, M, Mostert, M, Benjamin, DK, and Paolillo, P. "Pharmacological resolution of a multiloculated Candida spp. liver abscess in a preterm neonate." Early Human Development 89 Suppl 1 (June 2013): S47-S50. Full Text
- Wynn, JL, Hansen, NI, Das, A, Cotten, CM, Goldberg, RN, Sánchez, PJ, Bell, EF, Van Meurs, KP, Carlo, WA, Laptook, AR, Higgins, RD, Benjamin, DK, Stoll, BJ, and Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network, . "Early sepsis does not increase the risk of late sepsis in very low birth weight neonates." The Journal of Pediatrics 162, no. 5 (May 2013): 942-8.e1-3-null. Full Text
- Downey, LC, Benjamin, DK, Clark, RH, Watt, KM, Hornik, CP, Laughon, MM, Cohen-Wolkowiez, M, and Smith, PB. "Urinary tract infection concordance with positive blood and cerebrospinal fluid cultures in the neonatal intensive care unit." Journal of Perinatology : Official Journal of the California Perinatal Association 33, no. 4 (April 2013): 302-306. Full Text
- Bauserman, MS, Laughon, MM, Hornik, CP, Smith, PB, Benjamin, DK, Clark, RH, Engmann, C, and Cohen-Wolkowiez, M. "Group B Streptococcus and Escherichia coli infections in the intensive care nursery in the era of intrapartum antibiotic prophylaxis." The Pediatric Infectious Disease Journal 32, no. 3 (March 2013): 208-212. Full Text
- Lee, JH, Hornik, CP, Benjamin, DK, Herring, AH, Clark, RH, Cohen-Wolkowiez, M, and Smith, PB. "Risk factors for invasive candidiasis in infants >1500 g birth weight." Pediatr Infect Dis J 32, no. 3 (March 2013): 222-226. Full Text Link to Item
- Manzoni, P, Benjamin, DK, Franco, C, Rizzollo, S, Stronati, M, Watt, K, Cohen-Wolkowiez, M, and Jacqz-Aigrain, E. "Echinocandins for the nursery: an update." Current Drug Metabolism 14, no. 2 (February 2013): 203-207. (Review) Full Text
- Watt, K, Manzoni, P, Cohen-Wolkowiez, M, Rizzollo, S, Boano, E, Jacqz-Aigrain, E, and Benjamin, DK. "Triazole use in the nursery: fluconazole, voriconazole, posaconazole, and ravuconazole." Current Drug Metabolism 14, no. 2 (February 2013): 193-202. (Review) Full Text
- Buzzi, E, Manzoni, P, Castagnola, E, Benjamin, DK, Beghini, R, and Dall'Agnola, A. "Candida pneumonia in a term infant after prolonged use of inhaled corticosteroids for bronchopulmonary dysplasia (BPD)." Early Human Development 89, no. SUPPL.1 (2013): S62-S63. Full Text
- Testoni, D, Hornik, CP, Smith, PB, Benjamin, DK, and McKinney, RE. "Sports medicine and ethics." The American Journal of Bioethics : Ajob 13, no. 10 (January 2013): 4-12. Full Text
- Cohen-Wolkowiez, M, Poindexter, B, Bidegain, M, Weitkamp, J-H, Schelonka, RL, Randolph, DA, Ward, RM, Wade, K, Valencia, G, Burchfield, D, Arrieta, A, Mehta, V, Walsh, M, Kantak, A, Rasmussen, M, Sullivan, JE, Finer, N, Rich, W, Brozanski, BS, van den Anker, J, Blumer, J, Laughon, M, Watt, KM, Kearns, GL, Capparelli, EV, Martz, K, Berezny, K, Benjamin, DK, Smith, PB, and Meropenem Study Team, . "Safety and effectiveness of meropenem in infants with suspected or complicated intra-abdominal infections." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America 55, no. 11 (December 2012): 1495-1502. Full Text
- Steinbach, WJ, Roilides, E, Berman, D, Hoffman, JA, Groll, AH, Bin-Hussain, I, Palazzi, DL, Castagnola, E, Halasa, N, Velegraki, A, Dvorak, CC, Charkabarti, A, Sung, L, Danziger-Isakov, L, Lachenauer, C, Arrieta, A, Knapp, K, Abzug, MJ, Ziebold, C, Lehrnbecher, T, Klingspor, L, Warris, A, Leckerman, K, Martling, T, Walsh, TJ, Benjamin, DK, Zaoutis, TE, and International Pediatric Fungal Network, . "Results from a prospective, international, epidemiologic study of invasive candidiasis in children and neonates." The Pediatric Infectious Disease Journal 31, no. 12 (December 2012): 1252-1257. Full Text
- Tripathi, N, Watt, K, and Benjamin, DK. "Treatment and prophylaxis of invasive candidiasis." Semin Perinatol 36, no. 6 (December 2012): 416-423. (Review) Full Text Link to Item
- Lin, CB, Hornik, CP, Clark, R, Cotten, CM, Benjamin, DK, Cohen-Wolkoweiz, M, Smith, PB, and Wynn, JL. "Very low birth weight neonates who survive early-onset sepsis do not have an increased risk of developing late-onset sepsis." Early Hum Dev 88, no. 11 (November 2012): 905-909. Full Text Link to Item
- Infectious Diseases Society of America, . "White paper: recommendations on the conduct of superiority and organism-specific clinical trials of antibacterial agents for the treatment of infections caused by drug-resistant bacterial pathogens." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America 55, no. 8 (October 2012): 1031-1046. Full Text
- Watt, KM, Benjamin, DK, Cheifetz, IM, Moorthy, G, Wade, KC, Smith, PB, Brouwer, KLR, Capparelli, EV, and Cohen-Wolkowiez, M. "Pharmacokinetics and safety of fluconazole in young infants supported with extracorporeal membrane oxygenation." The Pediatric Infectious Disease Journal 31, no. 10 (October 2012): 1042-1047. Full Text
- Cohen-Wolkowiez, M, Watt, KM, Hornik, CP, Benjamin, DK, and Smith, PB. "Pharmacokinetics and tolerability of single-dose daptomycin in young infants." The Pediatric Infectious Disease Journal 31, no. 9 (September 2012): 935-937. Full Text
- Sampson, MR, Benjamin, DK, and Cohen-Wolkowiez, M. "Evidence-based guidelines for pediatric clinical trials: focus on StaR Child Health." Expert Rev Clin Pharmacol 5, no. 5 (September 2012): 525-531. Full Text Link to Item
- Schell, WA, Benton, JL, Smith, PB, Poore, M, Rouse, JL, Boles, DJ, Johnson, MD, Alexander, BD, Pamula, VK, Eckhardt, AE, Pollack, MG, Benjamin, DK, Perfect, JR, and Mitchell, TG. "Evaluation of a digital microfluidic real-time PCR platform to detect DNA of Candida albicans in blood." European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology 31, no. 9 (September 2012): 2237-2245. Full Text Open Access Copy
- Greenberg, RG, Benjamin, DK, Gantz, MG, Cotten, CM, Stoll, BJ, Walsh, MC, Sánchez, PJ, Shankaran, S, Das, A, Higgins, RD, Miller, NA, Auten, KJ, Walsh, TJ, Laptook, AR, Carlo, WA, Kennedy, KA, Finer, NN, Duara, S, Schibler, K, Ehrenkranz, RA, Van Meurs, KP, Frantz, ID, Phelps, DL, Poindexter, BB, Bell, EF, O'Shea, TM, Watterberg, KL, Goldberg, RN, Smith, PB, and Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network, . "Empiric antifungal therapy and outcomes in extremely low birth weight infants with invasive candidiasis." The Journal of Pediatrics 161, no. 2 (August 2012): 264-9.e2. Full Text
- Hornik, CP, Benjamin, DK, Becker, KC, Li, J, Clark, RH, Cohen-Wolkowiez, M, and Smith, PB. "Use of the complete blood cell count in early-onset neonatal sepsis." The Pediatric Infectious Disease Journal 31, no. 8 (August 2012): 799-802. Full Text
- Hornik, CP, Benjamin, DK, Becker, KC, Li, J, Clark, RH, Cohen-Wolkowiez, M, and Smith, PB. "Use of the complete blood cell count in late-onset neonatal sepsis." The Pediatric Infectious Disease Journal 31, no. 8 (August 2012): 803-807. Full Text
- Cohen-Wolkowiez, M, Benjamin, DK, Ross, A, James, LP, Sullivan, JE, Walsh, MC, Zadell, A, Newman, N, White, NR, Kashuba, ADM, and Ouellet, D. "Population pharmacokinetics of piperacillin using scavenged samples from preterm infants." Therapeutic Drug Monitoring 34, no. 3 (June 2012): 312-319. Full Text
- Doby, EH, Benjamin, DK, Blaschke, AJ, Ward, RM, Pavia, AT, Martin, PL, Driscoll, TA, Cohen-Wolkowiez, M, and Moran, C. "Therapeutic monitoring of voriconazole in children less than three years of age: a case report and summary of voriconazole concentrations for ten children." The Pediatric Infectious Disease Journal 31, no. 6 (June 2012): 632-635. Full Text
- Watt, KM, Cohen-Wolkowiez, M, Ward, RM, and Benjamin, DK. "Commentary: pediatric antifungal drug development: lessons learned and recommendations for the future." The Pediatric Infectious Disease Journal 31, no. 6 (June 2012): 635-637. Full Text
- Ascher, SB, Smith, PB, Clark, RH, Cohen-Wolkowiez, M, Li, JS, Watt, K, Jacqz-Aigrain, E, Kaguelidou, F, Manzoni, P, and Benjamin, DK. "Sepsis in young infants with congenital heart disease." Early Human Development 88 Suppl 2 (May 2012): S92-S97. Full Text
- Ascher, SB, Smith, PB, Watt, K, Benjamin, DK, Cohen-Wolkowiez, M, Clark, RH, and Moran, C. "Antifungal therapy and outcomes in infants with invasive Candida infections." The Pediatric Infectious Disease Journal 31, no. 5 (May 2012): 439-443. Full Text
- Hornik, CP, Fort, P, Clark, RH, Watt, K, Benjamin, DK, Smith, PB, Manzoni, P, Jacqz-Aigrain, E, Kaguelidou, F, and Cohen-Wolkowiez, M. "Early and late onset sepsis in very-low-birth-weight infants from a large group of neonatal intensive care units." Early Human Development 88 Suppl 2 (May 2012): S69-S74. Full Text
- Hsieh, E, Smith, PB, Jacqz-Aigrain, E, Kaguelidou, F, Cohen-Wolkowiez, M, Manzoni, P, and Benjamin, DK. "Neonatal fungal infections: when to treat?." Early Human Development 88 Suppl 2 (May 2012): S6-S10. (Review) Full Text
- Manzoni, P, Mostert, M, Latino, MA, Pugni, L, Stolfi, I, Decembrino, L, Vagnarelli, F, Corona, G, Tridapalli, E, Vetrano, G, Memo, L, Priolo, C, Galletto, P, Giovannozzi, C, Gallo, E, Pedicino, R, Barberi, I, Faldella, G, Mosca, F, Saia, OS, Bollani, L, Maragliano, R, Ruffinazzi, G, Tzialla, C, Stronati, M, Rizzollo, S, Farina, D, Benjamin, DK, Smith, PB, Jacqz-Aigrain, E, Kaguelidou, F, Cohen-Wolkowiez, and M, Italian Task Force for the Study and Prevention of Neonatal Fungal Infections et al. "Clinical characteristics and response to prophylactic fluconazole of preterm VLBW neonates with baseline and acquired fungal colonisation in NICU: data from a multicentre RCT." Early Hum Dev 88 Suppl 2 (May 2012): S60-S64. Full Text Link to Item
- Cohen-Wolkowiez, M, Ouellet, D, Smith, PB, James, LP, Ross, A, Sullivan, JE, Walsh, MC, Zadell, A, Newman, N, White, NR, Kashuba, ADM, and Benjamin, DK. "Population pharmacokinetics of metronidazole evaluated using scavenged samples from preterm infants." Antimicrobial Agents and Chemotherapy 56, no. 4 (April 2012): 1828-1837. Full Text
- Wynn, JL, Benjamin, DK, Benjamin, DK, Cohen-Wolkowiez, M, Clark, RH, and Smith, PB. "Very late onset infections in the neonatal intensive care unit." Early Hum Dev 88, no. 4 (April 2012): 217-225. Full Text Link to Item
- Testoni, D, Smith, PB, and Benjamin, DK. "The use of antifungal therapy in neonatal intensive care." Clinics in Perinatology 39, no. 1 (March 2012): 83-98. (Review) Full Text
- Warn, PA, Livermore, J, Howard, S, Felton, TW, Sharp, A, Gregson, L, Goodwin, J, Petraitiene, R, Petraitis, V, Cohen-Wolkowiez, M, Walsh, TJ, Benjamin, DK, and Hope, WW. "Anidulafungin for neonatal hematogenous Candida meningoencephalitis: identification of candidate regimens for humans using a translational pharmacological approach." Antimicrobial Agents and Chemotherapy 56, no. 2 (February 2012): 708-714. Full Text
- Watt, KM, Massaro, MM, Smith, B, Cohen-Wolkowiez, M, Benjamin, DK, and Laughon, MM. "Pharmacokinetics of moxifloxacin in an infant with Mycoplasma hominis meningitis." The Pediatric Infectious Disease Journal 31, no. 2 (February 2012): 197-199. Full Text
- Wynn, JL, Tan, S, Gantz, MG, Das, A, Goldberg, RN, Adams-Chapman, I, Stoll, BJ, Shankaran, S, Walsh, MC, Auten, KJ, Miller, NA, Sánchez, PJ, Higgins, RD, Cotten, CM, Smith, PB, Benjamin, DK, and NICHD Neonatal Research Network, . "Outcomes following candiduria in extremely low birth weight infants." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America 54, no. 3 (February 2012): 331-339. Full Text
- Bliss, JM, Wong, AY, Bhak, G, Laforce-Nesbitt, SS, Taylor, S, Tan, S, Stoll, BJ, Higgins, RD, Shankaran, S, and Jr, DKB. "Candida virulence properties and adverse clinical outcomes in neonatal candidiasis." Journal of Pediatrics 161, no. 3 (2012): 441-447.e2. Full Text
- Cotten, CM, Jr, DKB, Smith, PB, Stoll, BJ, Spitzer, AR, and Clark, RH. "Empirical antibiotic therapy for suspected early-onset bacterial sepsis." Pediatrics 130, no. 4 (2012): e1052-e1053. Full Text
- Sood, BG, Shankaran, S, Schelonka, RL, Saha, S, Benjamin, DK, Sánchez, PJ, Adams-Chapman, I, Stoll, BJ, Thorsen, P, Skogstrand, K, Ehrenkranz, RA, Hougaard, DM, Goldberg, RN, Tyson, JE, Das, A, Higgins, RD, and Carlo, WA. "Cytokine profiles of preterm neonates with fungal and bacterial sepsis." Pediatric Research 72, no. 2 (2012): 212-220. Full Text Open Access Copy
- Turner, K, Manzoni, P, Benjamin, DK, Cohen-Wolkowiez, M, Smith, PB, and Laughon, MM. "Fluconazole pharmacokinetics and safety in premature infants." Current Medicinal Chemistry 19, no. 27 (January 2012): 4617-4620. (Review) Full Text
- Cohen-Wolkowiez, M, White, NR, Bridges, A, Benjamin, DK, and Kashuba, ADM. "Development of a liquid chromatography-tandem mass spectrometry assay of six antimicrobials in plasma for pharmacokinetic studies in premature infants." Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences 879, no. 30 (November 2011): 3497-3506. Full Text
- Smith, PB, Cohen-Wolkowiez, M, Castro, LM, Poindexter, B, Bidegain, M, Weitkamp, J-H, Schelonka, RL, Ward, RM, Wade, K, Valencia, G, Burchfield, D, Arrieta, A, Bhatt-Mehta, V, Walsh, M, Kantak, A, Rasmussen, M, Sullivan, JE, Finer, N, Brozanski, BS, Sanchez, P, van den Anker, J, Blumer, J, Kearns, GL, Capparelli, EV, Anand, R, Benjamin, DK, and Meropenem Study Team, . "Population pharmacokinetics of meropenem in plasma and cerebrospinal fluid of infants with suspected or complicated intra-abdominal infections." The Pediatric Infectious Disease Journal 30, no. 10 (October 2011): 844-849. Full Text
- Laughon, MM, Benjamin, DK, Capparelli, EV, Kearns, GL, Berezny, K, Paul, IM, Wade, K, Barrett, J, Smith, PB, and Cohen-Wolkowiez, M. "Innovative clinical trial design for pediatric therapeutics." Expert Review of Clinical Pharmacology 4, no. 5 (September 2011): 643-652. (Review) Full Text
- Watt, K, Li, JS, Benjamin, DK, and Cohen-Wolkowiez, M. "Pediatric cardiovascular drug dosing in critically ill children and extracorporeal membrane oxygenation." Journal of Cardiovascular Pharmacology 58, no. 2 (August 2011): 126-132. (Review) Full Text
- Jean-Baptiste, N, Benjamin, DK, Cohen-Wolkowiez, M, Fowler, VG, Laughon, M, Clark, RH, and Smith, PB. "Coagulase-negative staphylococcal infections in the neonatal intensive care unit." Infect Control Hosp Epidemiol 32, no. 7 (July 2011): 679-686. Full Text Link to Item
- Greenberg, RG, Benjamin, DK, Cohen-Wolkowiez, M, Clark, RH, Cotten, CM, Laughon, M, and Smith, PB. "Repeat lumbar punctures in infants with meningitis in the neonatal intensive care unit." J Perinatol 31, no. 6 (June 2011): 425-429. Full Text Link to Item
- Cohen-Wolkowiez, M, Benjamin, DK, Piper, L, Cheifetz, IM, Moran, C, Liu, P, Aram, J, Kashuba, ADM, Capparelli, E, Walsh, TJ, Hope, WW, and Smith, PB. "Safety and pharmacokinetics of multiple-dose anidulafungin in infants and neonates." Clinical Pharmacology and Therapeutics 89, no. 5 (May 2011): 702-707. Full Text
- Piper, L, Smith, PB, Hornik, CP, Cheifetz, IM, Barrett, JS, Moorthy, G, Hope, WW, Wade, KC, Cohen-Wolkowiez, M, and Benjamin, DK. "Fluconazole loading dose pharmacokinetics and safety in infants." The Pediatric Infectious Disease Journal 30, no. 5 (May 2011): 375-378. Full Text
- Wallace, MC, Jaggers, J, Li, JS, Jacobs, ML, Jacobs, JP, Benjamin, DK, O'Brien, SM, Peterson, ED, Smith, PB, and Pasquali, SK. "Center variation in patient age and weight at Fontan operation and impact on postoperative outcomes." The Annals of Thoracic Surgery 91, no. 5 (May 2011): 1445-1452. Full Text
- Yanni, SB, Smith, PB, Benjamin, DK, Augustijns, PF, Thakker, DR, and Annaert, PP. "Higher clearance of micafungin in neonates compared with adults: role of age-dependent micafungin serum binding." Biopharmaceutics & Drug Disposition 32, no. 4 (May 2011): 222-232. Full Text
- Ascher, S, Smith, PB, and Benjamin, DK. "Safety of micafungin in infants: insights into optimal dosing." Expert Opinion on Drug Safety 10, no. 2 (March 2011): 281-286. (Review) Full Text
- Watt, K, Benjamin, DK, and Cohen-Wolkowiez, M. "Pharmacokinetics of antifungal agents in children." Early Human Development 87 Suppl 1 (March 2011): S61-S65. (Review) Full Text
- Pasquali, SK, Burstein, DS, Benjamin, DK, Smith, PB, and Li, JS. "In Reply." Pediatrics 127, no. 1 (January 1, 2011): e253-e254. Full Text
- Smith, PB, and Benjamin, DK. "Choosing the right empirical antibiotics for neonates." Archives of Disease in Childhood. Fetal and Neonatal Edition 96, no. 1 (January 2011): F2-F3. Full Text
- Wade, KC, and Benjamin, DK. "Clinical Pharmacology of Anti-Infective Drugs." (2011): 1160-1211. Full Text
- Benjamin, DK, Stoll, BJ, Gantz, MG, Walsh, MC, Sánchez, PJ, Das, A, Shankaran, S, Higgins, RD, Auten, KJ, Miller, NA, Walsh, TJ, Laptook, AR, Carlo, WA, Kennedy, KA, Finer, NN, Duara, S, Schibler, K, Chapman, RL, Van Meurs, KP, Frantz, ID, Phelps, DL, Poindexter, BB, Bell, EF, O'Shea, TM, Watterberg, KL, Goldberg, RN, and Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network, . "Neonatal candidiasis: epidemiology, risk factors, and clinical judgment." Pediatrics 126, no. 4 (October 2010): e865-e873. Full Text
- Manzoni, P, Rizzollo, S, Franco, C, Gallo, E, Galletto, P, Boano, E, Mostert, M, Benjamin, DK, Jacqz-Aigrain, E, and Farina, D. "Role of echinocandins in the management of fungal infections in neonates." J Matern Fetal Neonatal Med 23 Suppl 3 (October 2010): 49-52. (Review) Full Text Link to Item
- Yanni, SB, Augustijns, PF, Benjamin, DK, Brouwer, KLR, Thakker, DR, and Annaert, PP. "In vitro investigation of the hepatobiliary disposition mechanisms of the antifungal agent micafungin in humans and rats." Drug Metabolism and Disposition: the Biological Fate of Chemicals 38, no. 10 (October 2010): 1848-1856. Full Text
- Pasquali, SK, Burstein, DS, Benjamin, DK, Smith, PB, and Li, JS. "Globalization of pediatric research: analysis of clinical trials completed for pediatric exclusivity." Pediatrics 126, no. 3 (September 2010): e687-e692. Full Text
- Downey, LC, Smith, PB, and Benjamin, DK. "Risk factors and prevention of late-onset sepsis in premature infants." Early Human Development 86 Suppl 1 (July 2010): 7-12. (Review) Full Text
- Baker-Smith, CM, Benjamin, DK, Califf, RM, Murphy, MD, Li, JS, and Smith, PB. "Cough in pediatric patients receiving angiotensin-converting enzyme inhibitor therapy or angiotensin receptor blocker therapy in randomized controlled trials." Clinical Pharmacology and Therapeutics 87, no. 6 (June 2010): 668-671. Full Text
- Hope, WW, Smith, PB, Arrieta, A, Buell, DN, Roy, M, Kaibara, A, Walsh, TJ, Cohen-Wolkowiez, M, and Benjamin, DK. "Population pharmacokinetics of micafungin in neonates and young infants." Antimicrobial Agents and Chemotherapy 54, no. 6 (June 2010): 2633-2637. Full Text
- Li, JS, Benjamin, DK, Portman, RJ, and Severin, T. "Paediatric anti-hypertensive clinical trials and various factors influencing trial success or failure." (May 21, 2010): 196-205. (Chapter) Full Text
- Greenberg, RG, Moran, C, Ulshen, M, Smith, PB, Benjamin, DK, and Cohen-Wolkowiez, M. "Outcomes of catheter-associated infections in pediatric patients with short bowel syndrome." Journal of Pediatric Gastroenterology and Nutrition 50, no. 4 (April 2010): 460-462. Full Text
- Kehl-Fie, TE, Porsch, EA, Yagupsky, P, Grass, EA, Obert, C, Benjamin, DK, and St Geme, JW. "Examination of type IV pilus expression and pilus-associated phenotypes in Kingella kingae clinical isolates." Infection and Immunity 78, no. 4 (April 2010): 1692-1699. Full Text
- Nowell, L, Moran, C, Smith, PB, Seed, P, Alexander, BD, Cotten, CM, Wiener, JS, and Benjamin, DK. "Prevalence of renal anomalies after urinary tract infections in hospitalized infants less than 2 months of age." J Perinatol 30, no. 4 (April 2010): 281-285. Full Text Open Access Copy Link to Item
- Barker, GM, O'Brien, SM, Welke, KF, Jacobs, ML, Jacobs, JP, Benjamin, DK, Peterson, ED, Jaggers, J, and Li, JS. "Major infection after pediatric cardiac surgery: a risk estimation model." The Annals of Thoracic Surgery 89, no. 3 (March 2010): 843-850. Full Text
- Downey, LC, Smith, PB, Benjamin, DK, and Cohen-Wolkowiez, M. "Recent Advances in the Detection of Neonatal Candidiasis." Curr Fungal Infect Rep 4, no. 1 (March 1, 2010): 17-22. Full Text Link to Item
- Moran, C, Grussemeyer, CA, Spalding, JR, Benjamin, DK, and Reed, SD. "Comparison of costs, length of stay, and mortality associated with Candida glabrata and Candida albicans bloodstream infections." American Journal of Infection Control 38, no. 1 (February 2010): 78-80. Full Text
- Benjamin, DK, Smith, PB, Arrieta, A, Castro, L, Sánchez, PJ, Kaufman, D, Arnold, LJ, Kovanda, LL, Sawamoto, T, Buell, DN, Hope, WW, and Walsh, TJ. "Safety and pharmacokinetics of repeat-dose micafungin in young infants." Clinical Pharmacology and Therapeutics 87, no. 1 (January 2010): 93-99. Full Text
- Kishnani, PS, Goldenberg, PC, DeArmey, SL, Heller, J, Benjamin, D, Young, S, Bali, D, Smith, SA, Li, JS, Mandel, H, Koeberl, D, Rosenberg, A, and Chen, Y-T. "Cross-reactive immunologic material status affects treatment outcomes in Pompe disease infants." Mol Genet Metab 99, no. 1 (January 2010): 26-33. Full Text Link to Item
- Moran, C, and Benjamin, D. "Treatment of neonatal fungal infections." Advances in Experimental Medicine and Biology 659 (2010): 129-138. Full Text
- Yanni, SB, Annaert, PP, Augustijns, P, Ibrahim, JG, Benjamin, DK, and Thakker, DR. "In vitro hepatic metabolism explains higher clearance of voriconazole in children versus adults: role of CYP2C19 and flavin-containing monooxygenase 3." Drug Metab Dispos 38, no. 1 (January 2010): 25-31. Full Text Link to Item
- Benjamin, DK, Smith, PB, Sun, MJM, Murphy, MD, Avant, D, Mathis, L, Rodriguez, W, Califf, RM, and Li, JS. "Safety and transparency of pediatric drug trials." Archives of Pediatrics & Adolescent Medicine 163, no. 12 (December 2009): 1080-1086. Full Text
- Cohen-Wolkowiez, M, Benjamin, DK, and Smith, PB. "Management of neonatal candidiasis." Journal of Invasive Fungal Infections 3, no. 1 (December 1, 2009): 9-14. (Review)
- Cohen-Wolkowiez, M, Moran, C, Benjamin, DK, Cotten, CM, Clark, RH, and Smith, PB. "Early and late onset sepsis in late preterm infants." The Pediatric Infectious Disease Journal 28, no. 12 (December 2009): 1052-1056. Full Text
- Cohen-Wolkowiez, M, Moran, C, Benjamin, DK, and Smith, PB. "Pediatric antifungal agents." Current Opinion in Infectious Diseases 22, no. 6 (December 2009): 553-558. (Review) Full Text
- Moran, C, Smith, PB, Cohen-Wolkowiez, M, and Benjamin, DK. "Clinical trial design in neonatal pharmacology: effect of center differences, with lessons from the Pediatric Oncology Cooperative Research experience." Clinical Pharmacology and Therapeutics 86, no. 6 (December 2009): 589-591. Full Text
- Ansong, AK, Smith, PB, Benjamin, DK, Clark, RH, Li, JS, Cotten, CM, Mangum, B, and Garges, HP. "Group B streptococcal meningitis: cerebrospinal fluid parameters in the era of intrapartum antibiotic prophylaxis." Early Human Development 85, no. 10 Suppl (October 2009): S5-S7. Full Text
- Roilides, E, Zaoutis, TE, Katragkou, A, Benjamin, DK, and Walsh, TJ. "Zygomycosis in neonates: an uncommon but life-threatening infection." American Journal of Perinatology 26, no. 8 (September 2009): 565-573. (Review) Full Text
- Wade, KC, Benjamin, DK, Kaufman, DA, Ward, RM, Smith, PB, Jayaraman, B, Adamson, PC, Gastonguay, MR, and Barrett, JS. "Fluconazole dosing for the prevention or treatment of invasive candidiasis in young infants." The Pediatric Infectious Disease Journal 28, no. 8 (August 2009): 717-723. Full Text
- Johnson, OO, Benjamin, DK, Schimana, W, Tillekeratne, LG, Crump, JA, Landman, KZ, Kinabo, GD, Mmbaga, B, Msuya, LJ, Shao, JF, Swai, ME, and Cunningham, CK. "Total lymphocyte count and World Health Organization pediatric clinical stage as markers to assess need to initiate antiretroviral therapy among human immunodeficiency virus-infected children in Moshi, Northern Tanzania." The Pediatric Infectious Disease Journal 28, no. 6 (June 2009): 493-497. Full Text
- Moran, C, Grussemeyer, CA, Spalding, JR, Benjamin, DK, and Reed, SD. "Candida albicans and non-albicans bloodstream infections in adult and pediatric patients: comparison of mortality and costs." The Pediatric Infectious Disease Journal 28, no. 5 (May 2009): 433-435. Full Text
- Smith, PB, Walsh, TJ, Hope, W, Arrieta, A, Takada, A, Kovanda, LL, Kearns, GL, Kaufman, D, Sawamoto, T, Buell, DN, and Benjamin, DK. "Pharmacokinetics of an elevated dosage of micafungin in premature neonates." The Pediatric Infectious Disease Journal 28, no. 5 (May 2009): 412-415. Full Text
- Cohen-Wolkowiez, M, Benjamin, DK, and Capparelli, E. "Immunotherapy in neonatal sepsis: advances in treatment and prophylaxis." Current Opinion in Pediatrics 21, no. 2 (April 2009): 177-181. (Review) Full Text
- Schultz, ED, Tanaka, DT, Goldberg, RN, Benjamin, DK, and Smith, PB. "Effect of methicillin-resistant Staphylococcus aureus colonization in the neonatal intensive care unit on total hospital cost." Infect Control Hosp Epidemiol 30, no. 4 (April 2009): 383-385. Full Text Link to Item
- Pappas, PG, Kauffman, CA, Andes, D, Benjamin, DK, Calandra, TF, Edwards, JE, Filler, SG, Fisher, JF, Kullberg, B-J, Ostrosky-Zeichner, L, Reboli, AC, Rex, JH, Walsh, TJ, Sobel, JD, and Infectious Diseases Society of America, . "Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America 48, no. 5 (March 2009): 503-535. Full Text
- Stryjewski, ME, Kanafani, ZA, Chu, VH, Pappas, PA, Harding, T, Drew, LA, Benjamin, DK, Reller, LB, Lee, BA, Corey, GR, and Fowler, VG. "Staphylococcus aureus bacteremia among patients with health care-associated fever." Am J Med 122, no. 3 (March 2009): 281-289.e2. Full Text Link to Item
- Cotten, CM, Taylor, S, Stoll, B, Goldberg, RN, Hansen, NI, Sánchez, PJ, Ambalavanan, N, Benjamin, DK, and NICHD Neonatal Research Network, . "Prolonged duration of initial empirical antibiotic treatment is associated with increased rates of necrotizing enterocolitis and death for extremely low birth weight infants." Pediatrics 123, no. 1 (January 2009): 58-66. Full Text
- Greenberg, RG, Smith, PB, Cotten, CM, Moody, MA, Clark, RH, and Benjamin, DK. "Traumatic lumbar punctures in neonates: test performance of the cerebrospinal fluid white blood cell count." The Pediatric Infectious Disease Journal 27, no. 12 (December 2008): 1047-1051. Full Text
- Wade, KC, Wu, D, Kaufman, DA, Ward, RM, Benjamin, DK, Sullivan, JE, Ramey, N, Jayaraman, B, Hoppu, K, Adamson, PC, Gastonguay, MR, Barrett, JS, and National Institute of Child Health and Development Pediatric Pharmacology Research Unit Network, . "Population pharmacokinetics of fluconazole in young infants." Antimicrobial Agents and Chemotherapy 52, no. 11 (November 2008): 4043-4049. Full Text
- Wilfret, DA, Baker, BT, Palavecino, E, Moran, C, and Benjamin, DK. "Epidemiology of respiratory syncytial virus in various regions within North Carolina during multiple seasons." N C Med J 69, no. 6 (November 2008): 447-452. Link to Item
- Baker-Smith, CM, Benjamin, DK, Grabowski, HG, Reid, ED, Mangum, B, Goldsmith, JV, Murphy, MD, Edwards, R, Eisenstein, EL, Sun, J, Califf, RM, and Li, JS. "The economic returns of pediatric clinical trials of antihypertensive drugs." American Heart Journal 156, no. 4 (October 2008): 682-688. Full Text
- McDowell, R, Li, JS, Benjamin, DK, Morgan, C, Becker, A, Kishnani, PS, and Kanter, RJ. "Arrhythmias in patients receiving enzyme replacement therapy for infantile Pompe disease." Genetics in Medicine : Official Journal of the American College of Medical Genetics 10, no. 10 (October 2008): 758-762. Full Text
- Li, JS, Baker-Smith, CM, Smith, PB, Hasselblad, V, Murphy, MD, Califf, RM, and Benjamin, DK. "Racial differences in blood pressure response to angiotensin-converting enzyme inhibitors in children: a meta-analysis." Clinical Pharmacology and Therapeutics 84, no. 3 (September 2008): 315-319. (Review) Full Text
- Smith, PB, Benjamin, DK, Murphy, MD, Johann-Liang, R, Iyasu, S, Gould, B, Califf, RM, Li, JS, and Rodriguez, W. "Safety monitoring of drugs receiving pediatric marketing exclusivity." Pediatrics 122, no. 3 (September 2008): e628-e633. Full Text
- Wratney, AT, Benjamin, DK, Slonim, AD, He, J, Hamel, DS, and Cheifetz, IM. "The endotracheal tube air leak test does not predict extubation outcome in critically ill pediatric patients." Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 9, no. 5 (September 2008): 490-496. Full Text
- Smith, PB, Benjamin, DK, Cotten, CM, Schultz, E, Guo, R, Nowell, L, Smithwick, ML, and Thornburg, CD. "Is an increased dwell time of a peripherally inserted catheter associated with an increased risk of bloodstream infection in infants?." Infection Control and Hospital Epidemiology 29, no. 8 (August 2008): 749-753. Full Text
- Smith, PB, Garges, HP, Cotton, CM, Walsh, TJ, Clark, RH, and Benjamin, DK. "Meningitis in preterm neonates: importance of cerebrospinal fluid parameters." Am J Perinatol 25, no. 7 (August 2008): 421-426. Full Text Link to Item
- Baddley, JW, Benjamin, DK, Patel, M, Miró, J, Athan, E, Barsic, B, Bouza, E, Clara, L, Elliott, T, Kanafani, Z, Klein, J, Lerakis, S, Levine, D, Spelman, D, Rubinstein, E, Tornos, P, Morris, AJ, Pappas, P, Fowler, VG, Chu, VH, Cabell, C, and International Collaboration on Endocarditis-Prospective Cohort Study Group (ICE-PCS), . "Candida infective endocarditis." European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology 27, no. 7 (July 2008): 519-529. Full Text
- Yanni, SB, Annaert, PP, Augustijns, P, Bridges, A, Gao, Y, Benjamin, DK, and Thakker, DR. "Role of flavin-containing monooxygenase in oxidative metabolism of voriconazole by human liver microsomes." Drug Metabolism and Disposition: the Biological Fate of Chemicals 36, no. 6 (June 2008): 1119-1125. Full Text
- Grussemeyer, CA, Friedman, JY, Spalding, JR, Benjamin, DK, Moran, C, and Reed, SD. "IN1 C. ALBICANS AND C. GLABRATA BLOODSTREAM INFECTIONS IN ADULTS: OUTCOMES AND ASSOCIATED COSTS." Value in Health 11, no. 3 (May 2008): A24-A24. Full Text
- Benjamin, DK, Smith, PB, Jadhav, P, Gobburu, JV, Murphy, MD, Hasselblad, V, Baker-Smith, C, Califf, RM, and Li, JS. "Pediatric antihypertensive trial failures: analysis of end points and dose range." Hypertension (Dallas, Tex. : 1979) 51, no. 4 (April 2008): 834-840. Full Text
- Benjamin, DK. "First, do no harm." Pediatrics 121, no. 4 (April 2008): 831-832. Full Text
- Koeberl, DD, Pinto, C, Sun, B, Li, S, Kozink, DM, Benjamin, DK, Demaster, AK, Kruse, MA, Vaughn, V, Hillman, S, Bird, A, Jackson, M, Brown, T, Kishnani, PS, and Chen, Y-T. "AAV vector-mediated reversal of hypoglycemia in canine and murine glycogen storage disease type Ia." Mol Ther 16, no. 4 (April 2008): 665-672. Full Text Link to Item
- Smith, PB, Li, JS, Murphy, MD, Califf, RM, and Benjamin, DK. "Safety of placebo controls in pediatric hypertension trials." Hypertension (Dallas, Tex. : 1979) 51, no. 4 (April 2008): 829-833. Full Text
- Cohen-Wolkowiez, M, Smith, PB, Benjamin, DK, Fowler, VG, and Wade, KC. "Daptomycin use in infants: report of two cases with peak and trough drug concentrations." Journal of Perinatology : Official Journal of the California Perinatal Association 28, no. 3 (March 2008): 233-234. Full Text
- Crowley, AL, Peterson, GE, Benjamin, DK, Rimmer, SH, Todd, C, Cabell, CH, Reller, LB, Ryan, T, Corey, GR, and Fowler, VG. "Venous thrombosis in patients with short- and long-term central venous catheter-associated Staphylococcus aureus bacteremia." Critical Care Medicine 36, no. 2 (February 2008): 385-390. Full Text
- Hope, WW, Mickiene, D, Petraitis, V, Petraitiene, R, Kelaher, AM, Hughes, JE, Cotton, MP, Bacher, J, Keirns, JJ, Buell, D, Heresi, G, Benjamin, DK, Groll, AH, Drusano, GL, and Walsh, TJ. "The pharmacokinetics and pharmacodynamics of micafungin in experimental hematogenous Candida meningoencephalitis: implications for echinocandin therapy in neonates." The Journal of Infectious Diseases 197, no. 1 (January 2008): 163-171. Full Text
- Thornburg, CD, Smith, PB, Smithwick, ML, Cotten, CM, and Benjamin, DK. "Association between thrombosis and bloodstream infection in neonates with peripherally inserted catheters." Thrombosis Research 122, no. 6 (January 2008): 782-785. Full Text
- Cohen-Wolkowiez, M, Benjamin, DK, Fowler, VG, Wade, KC, Alexander, BD, Worley, G, Goldstein, RF, and Smith, PB. "Mortality and neurodevelopmental outcome after Staphylococcus aureus bacteremia in infants." The Pediatric Infectious Disease Journal 26, no. 12 (December 2007): 1159-1161. Full Text
- Morpeth, S, Murdoch, D, Cabell, CH, Karchmer, AW, Pappas, P, Levine, D, Nacinovich, F, Tattevin, P, Fernández-Hidalgo, N, Dickerman, S, Bouza, E, Río, AD, Lejko-Zupanc, T, Ramos, ADO, Iarussi, D, Klein, J, Chirouze, C, Bedimo, R, Corey, GR, Jr, VGF, and Investigators, ICOEPCSICE-PCS. "Non-HACEK gram-negative bacillus endocarditis." Annals of internal medicine 147, no. 12 (December 2007): 829-835. (Academic Article)
- Lenfestey, RW, Smith, PB, Moody, MA, Clark, RH, Cotten, CM, Seed, PC, and Benjamin, DK. "Predictive value of cerebrospinal fluid parameters in neonates with intraventricular drainage devices." J Neurosurg 107, no. 3 Suppl (September 2007): 209-212. Full Text Link to Item
- Smith, PB, Benjamin, DK, Alexander, BD, Johnson, MD, Finkelman, MA, and Steinbach, WJ. "Quantification of 1,3-beta-D-glucan levels in children: preliminary data for diagnostic use of the beta-glucan assay in a pediatric setting." Clinical and Vaccine Immunology : Cvi 14, no. 7 (July 2007): 924-925. Full Text
- Santos, RP, Sánchez, PJ, Mejias, A, Benjamin, DK, Walsh, TJ, Patel, S, and Jafri, HS. "Successful medical treatment of cutaneous aspergillosis in a premature infant using liposomal amphotericin B, voriconazole and micafungin." The Pediatric Infectious Disease Journal 26, no. 4 (April 2007): 364-366. Full Text
- Smith, PB, Morgan, J, Benjamin, JDK, Fridkin, SK, Sanza, LT, Harrison, LH, Sofair, AN, Huie-White, S, and Benjamin, DK. "Excess costs of hospital care associated with neonatal candidemia." Pediatr Infect Dis J 26, no. 3 (March 2007): 197-200. Link to Item
- Cohen-Wolkowiez, M, Smith, PB, Mangum, B, Steinbach, WJ, Alexander, BD, Cotten, CM, Clark, RH, Walsh, TJ, and Benjamin, DK. "Neonatal Candida meningitis: significance of cerebrospinal fluid parameters and blood cultures." Journal of Perinatology : Official Journal of the California Perinatal Association 27, no. 2 (February 2007): 97-100. Full Text
- Li, JS, Eisenstein, EL, Grabowski, HG, Reid, ED, Mangum, B, Schulman, KA, Goldsmith, JV, Murphy, MD, Califf, RM, and Benjamin, DK. "Economic return of clinical trials performed under the pediatric exclusivity program." Jama 297, no. 5 (February 2007): 480-488. Full Text Open Access Copy
- Smith, PB, Steinbach, WJ, Cotten, CM, Schell, WA, Perfect, JR, Walsh, TJ, and Benjamin, DK. "Caspofungin for the treatment of azole resistant candidemia in a premature infant." Journal of Perinatology : Official Journal of the California Perinatal Association 27, no. 2 (February 2007): 127-129. Full Text
- Stryjewski, ME, Szczech, LA, Benjamin, DK, Inrig, JK, Kanafani, ZA, Engemann, JJ, Chu, VH, Joyce, MJ, Reller, LB, Corey, GR, and Fowler, VG. "Use of vancomycin or first-generation cephalosporins for the treatment of hemodialysis-dependent patients with methicillin-susceptible Staphylococcus aureus bacteremia." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America 44, no. 2 (January 2007): 190-196. Full Text
- Benjamin, DK, and Stoll, BJ. "Infection in late preterm infants." Clinics in Perinatology 33, no. 4 (December 2006): 871-x. (Review) Full Text
- Sun, B, Zhang, H, Benjamin, DK, Brown, T, Bird, A, Young, SP, McVie-Wylie, A, Chen, Y-T, and Koeberl, DD. "Enhanced efficacy of an AAV vector encoding chimeric, highly secreted acid alpha-glucosidase in glycogen storage disease type II." Molecular Therapy : the Journal of the American Society of Gene Therapy 14, no. 6 (December 2006): 822-830. Full Text
- Freedman, J, Guller, U, Benjamin, DK, Higgins, LD, Pan, D, Cook, C, and Pietrobon, R. "National trends in health care utilization and racial and socioeconomic disparities in pediatric pyogenic arthritis." J Pediatr Orthop 26, no. 6 (November 2006): 709-715. Full Text Link to Item
- Anaissie, EJ, Segal, BH, Graybill, JR, Arndt, C, Perfect, JR, Kleinberg, M, Pappas, P, Benjamin, D, Rubin, R, Aberg, JA, Adderson, EE, Adler-Shohet, FC, Akan, H, Akova, M, Almyroudis, NG, Alexander, BD, Andes, D, Arrieta, A, Baddley, JW, Barron, MA, Belzberg, H, Boucher, HW, Boyce, TG, Casadevall, A, Chandrasekar, PH, Cleary, JD, Cordonnier, C, Cornely, OA, Cuenca-Estrella, M, Daly, JS, Daoura, N, Denning, DW, dePauw, B, de Repentigny, L, Dignani, MC, Dismukes, WE, Donnelly, JP, Donowitz, GR, Dupont, B, Drusano, G, Ellis, M, Espinel-Ingroff, A, Fishman, JA, Fleming, R, Forrest, G, Ghannoum, M, Goldman, M, Grazziutti, M, Greene, JN, Greenberg, RN, Gubbins, PO, Hadley, S, Herbrecht, R, Hiemenz, JW, Hope, W, Hospenthal, DR, Husain, S, Ito, JI, Jacobson, RM, Johnson, M, Keating, MR, Kett, DH, Knapp, K, Kontoyiannis, DP, Krcmery, VC, Larsen, R, Laverdiere, M, Ljungman, P, Lortholary, O, Maertens, J, Marriott, D, Mattiuzzi, G, McGinnis, MR, Morris, M, Nucci, M, Odds, FC, Pankey, GA, Patterson, T, Pfaller, M, Razonable, RR, Reboli, AC, Rinaldi, MG, Roberts, GD, Rodriguez Tudela, JL, Rotstein, C, Ruhnke, M, Schuster, M, Shoham, S, Sia, IG, Siebel, N, Silviera, F, Singh, N, Sobel, J, Solomkin, JS, Sorrell, TC, Steinbach, WJ, Temesgen, Z, Tortorano, A, Vartivarian, S, VerWeij, P, Viscoli, C, Viviani, MA, Walker, RC, Wheat, JL, Wiley, J, Williamson, P, Wingard, JR, Yu, VL, and Zaoutis, T. "Clinical research in the lay press: irresponsible journalism raises a huge dose of doubt." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America 43, no. 8 (October 2006): 1031-1039. Full Text
- Benjamin, DK, Smith, PB, Murphy, MD, Roberts, R, Mathis, L, Avant, D, Califf, RM, and Li, JS. "Peer-reviewed publication of clinical trials completed for pediatric exclusivity." Jama 296, no. 10 (September 2006): 1266-1273. Full Text
- Koeberl, DD, Sun, BD, Damodaran, TV, Brown, T, Millington, DS, Benjamin, DK, Bird, A, Schneider, A, Hillman, S, Jackson, M, Beaty, RM, and Chen, YT. "Early, sustained efficacy of adeno-associated virus vector-mediated gene therapy in glycogen storage disease type Ia." Gene Therapy 13, no. 17 (September 2006): 1281-1289. Full Text
- Ward, RM, Benitz, WE, Benjamin, DK, Blackmon, L, Giacoia, GP, Hudak, M, Lasky, T, Rodriguez, W, and Selen, A. "Criteria supporting the study of drugs in the newborn." Clinical Therapeutics 28, no. 9 (September 2006): 1385-1398. (Review) Full Text
- Cohen-Wolkowiez, M, Benjamin, DK, Steinbach, WJ, and Smith, PB. "Anidulafungin: a new echinocandin for the treatment of fungal infections." Drugs of Today (Barcelona, Spain : 1998) 42, no. 8 (August 2006): 533-544. (Review) Full Text
- Cotten, CM, McDonald, S, Stoll, B, Goldberg, RN, Poole, K, Benjamin, DK, and National Institute for Child Health and Human Development Neonatal Research Network, . "The association of third-generation cephalosporin use and invasive candidiasis in extremely low birth-weight infants." Pediatrics 118, no. 2 (August 2006): 717-722. Full Text
- Menon, S, Berezny, KY, Kilaru, R, Benjamin, DK, Kay, JD, Hazan, L, Portman, R, Hogg, R, Deitchman, D, Califf, RM, and Li, JS. "Racial differences are seen in blood pressure response to fosinopril in hypertensive children." American Heart Journal 152, no. 2 (August 2006): 394-399. Full Text
- Nageswaran, S, Woods, CR, Benjamin, DK, Givner, LB, and Shetty, AK. "Orbital cellulitis in children." The Pediatric Infectious Disease Journal 25, no. 8 (August 2006): 695-699. Full Text
- Brooks, R, Woods, CW, Benjamin, DK, and Rosenstein, NE. "Increased case-fatality rate associated with outbreaks of Neisseria meningitidis infection, compared with sporadic meningococcal disease, in the United States, 1994-2002." Clin Infect Dis 43, no. 1 (July 1, 2006): 49-54. Full Text Link to Item
- Steinbach, WJ, Cramer, RA, Perfect, BZ, Asfaw, YG, Sauer, TC, Najvar, LK, Kirkpatrick, WR, Patterson, TF, Benjamin, DK, Heitman, J, and Perfect, JR. "Calcineurin controls growth, morphology, and pathogenicity in Aspergillus fumigatus." Eukaryotic Cell 5, no. 7 (July 2006): 1091-1103. Full Text
- Benjamin, DK, Schelonka, R, White, R, Holley, HP, Bifano, E, Cummings, J, Adcock, K, Kaufman, D, Puppala, B, Riedel, P, Hall, B, White, J, Cotton, CM, and S. aureus prevention investigators, . "A blinded, randomized, multicenter study of an intravenous Staphylococcus aureus immune globulin." Journal of Perinatology : Official Journal of the California Perinatal Association 26, no. 5 (May 2006): 290-295. Full Text
- Garges, HP, Moody, MA, Cotten, CM, Smith, PB, Tiffany, KF, Lenfestey, R, Li, JS, Fowler, VG, and Benjamin, DK. "Neonatal meningitis: what is the correlation among cerebrospinal fluid cultures, blood cultures, and cerebrospinal fluid parameters?." Pediatrics 117, no. 4 (April 2006): 1094-1100. Full Text
- Benjamin, DK, Driscoll, T, Seibel, NL, Gonzalez, CE, Roden, MM, Kilaru, R, Clark, K, Dowell, JA, Schranz, J, and Walsh, TJ. "Safety and pharmacokinetics of intravenous anidulafungin in children with neutropenia at high risk for invasive fungal infections." Antimicrobial Agents and Chemotherapy 50, no. 2 (February 2006): 632-638. Full Text
- Smith, PB, Cotten, CM, Garges, HP, Tiffany, KF, Lenfestey, RW, Moody, MA, Li, JS, and Benjamin, DK. "A comparison of neonatal Gram-negative rod and Gram-positive cocci meningitis." J Perinatol 26, no. 2 (February 2006): 111-114. Full Text Link to Item
- Benjamin, DK, Stoll, BJ, Fanaroff, AA, McDonald, SA, Oh, W, Higgins, RD, Duara, S, Poole, K, Laptook, A, Goldberg, R, and National Institute of Child Health and Human Development Neonatal Research Network, . "Neonatal candidiasis among extremely low birth weight infants: risk factors, mortality rates, and neurodevelopmental outcomes at 18 to 22 months." Pediatrics 117, no. 1 (January 2006): 84-92. Full Text
- Schelonka, RL, Katz, B, Waites, KB, and Benjamin, DK. "Critical appraisal of the role of Ureaplasma in the development of bronchopulmonary dysplasia with metaanalytic techniques." The Pediatric Infectious Disease Journal 24, no. 12 (December 2005): 1033-1039. Full Text
- Steinbach, WJ, and Benjamin, DK. "New antifungal agents under development in children and neonates." Curr Opin Infect Dis 18, no. 6 (December 2005): 484-489. (Review) Link to Item
- Steinbach, WJ, Perfect, JR, Cabell, CH, Fowler, VG, Corey, GR, Li, JS, Zaas, AK, and Benjamin, DK. "A meta-analysis of medical versus surgical therapy for Candida endocarditis." The Journal of Infection 51, no. 3 (October 2005): 230-247. Full Text
- Smith, PB, Steinbach, WJ, and Benjamin, DK. "Neonatal candidiasis." Infectious Disease Clinics of North America 19, no. 3 (September 2005): 603-615. (Review) Full Text
- Nielsen, K, Cox, GM, Litvintseva, AP, Mylonakis, E, Malliaris, SD, Benjamin, DK, Giles, SS, Mitchell, TG, Casadevall, A, Perfect, JR, and Heitman, J. "Cryptococcus neoformans {alpha} strains preferentially disseminate to the central nervous system during coinfection." Infection and Immunity 73, no. 8 (August 2005): 4922-4933. Full Text
- Tiffany, KF, Smith, PB, and Benjamin, DK. "Neonatal candidiasis: prophylaxis and treatment." Expert Opin Pharmacother 6, no. 10 (August 2005): 1647-1655. (Review) Full Text Link to Item
- Zaoutis, TE, Benjamin, DK, and Steinbach, WJ. "Antifungal treatment in pediatric patients." Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy 8, no. 4 (August 2005): 235-245. (Review) Full Text
- Brian Smith, P, Steinbach, WJ, and Benjamin, DK. "Invasive Candida infections in the neonate." Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy 8, no. 3 (June 2005): 147-162. (Review) Full Text
- El-Ahdab, F, Benjamin, DK, Wang, A, Cabell, CH, Chu, VH, Stryjewski, ME, Corey, GR, Sexton, DJ, Reller, LB, and Fowler, VG. "Risk of endocarditis among patients with prosthetic valves and Staphylococcus aureus bacteremia." Am J Med 118, no. 3 (March 2005): 225-229. Full Text Link to Item
- Fowler, VG, Justice, A, Moore, C, Benjamin, DK, Woods, CW, Campbell, S, Reller, LB, Corey, GR, Day, NPJ, and Peacock, SJ. "Risk factors for hematogenous complications of intravascular catheter-associated Staphylococcus aureus bacteremia." Clinical Infectious Diseases: an Official Publication of the Infectious Diseases Society of America 40, no. 5 (March 2005): 695-703. Full Text
- Tiffany, KF, Benjamin, DK, Palasanthiran, P, O'Donnell, K, and Gutman, LT. "Improved neurodevelopmental outcomes following long-term high-dose oral acyclovir therapy in infants with central nervous system and disseminated herpes simplex disease." J Perinatol 25, no. 3 (March 2005): 156-161. Full Text Link to Item
- Steinbach, WJ, Singh, N, Miller, JL, Benjamin, DK, Schell, WA, Heitman, J, and Perfect, JR. "In vitro interactions between antifungals and immunosuppressants against Aspergillus fumigatus isolates from transplant and nontransplant patients." Antimicrobial Agents and Chemotherapy 48, no. 12 (December 2004): 4922-4925. Full Text
- Benjamin, DK, Hirschfeld, S, Cunningham, CK, and McKinney, RE. "Growth as a part of the composite endpoint in paediatric antiretroviral clinical trials." J Antimicrob Chemother 54, no. 4 (October 2004): 701-703. Full Text Link to Item
- Steinbach, WJ, Benjamin, DK, Trasi, SA, Miller, JL, Schell, WA, Zaas, AK, Foster, WM, and Perfect, JR. "Value of an inhalational model of invasive aspergillosis." Medical Mycology 42, no. 5 (October 2004): 417-425. Full Text
- Steinbach, WJ, Perfect, JR, Schell, WA, Walsh, TJ, and Benjamin, DK. "In vitro analyses, animal models, and 60 clinical cases of invasive Aspergillus terreus infection." Antimicrobial Agents and Chemotherapy 48, no. 9 (September 2004): 3217-3225. (Review) Full Text
- Chu, VH, Cabell, CH, Benjamin, DK, Kuniholm, EF, Fowler, VG, Engemann, J, Sexton, DJ, Corey, GR, and Wang, A. "Infective endocarditis: Should diabetic patients be treated more aggressively? Response." CIRCULATION 110, no. 7 (August 17, 2004): E72-E72. Link to Item
- Dixon, TC, Steinbach, WJ, Benjamin, DK, Williams, LW, and Myers, LA. "Disseminated Candida tropicalis in a patient with chronic mucocutaneous candidiasis." South Med J 97, no. 8 (August 2004): 788-790. Link to Item
- Clark, R, Powers, R, White, R, Bloom, B, Sanchez, P, and Benjamin, DK. "Prevention and treatment of nosocomial sepsis in the NICU." Journal of Perinatology : Official Journal of the California Perinatal Association 24, no. 7 (July 2004): 446-453. (Review) Full Text
- Steinbach, WJ, Benjamin, DK, Kontoyiannis, DP, Perfect, JR, Lutsar, I, Marr, KA, Lionakis, MS, Torres, HA, Jafri, H, and Walsh, TJ. "Infections due to Aspergillus terreus: a multicenter retrospective analysis of 83 cases." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America 39, no. 2 (July 2004): 192-198. Full Text
- Clark, R, Powers, R, White, R, Bloom, B, Sanchez, P, and Benjamin, DK. "Nosocomial infection in the NICU: a medical complication or unavoidable problem?." Journal of Perinatology : Official Journal of the California Perinatal Association 24, no. 6 (June 2004): 382-388. (Review) Full Text
- Cunnion, KM, Benjamin, DK, Hester, CG, and Frank, MM. "Role of complement receptors 1 and 2 (CD35 and CD21), C3, C4, and C5 in survival by mice of Staphylococcus aureus bacteremia." J Lab Clin Med 143, no. 6 (June 2004): 358-365. Full Text Link to Item
- Chu, VH, Cabell, CH, Benjamin, DK, Kuniholm, EF, Fowler, VG, Engemann, J, Sexton, DJ, Corey, GR, and Wang, A. "Early predictors of in-hospital death in infective endocarditis." Circulation 109, no. 14 (April 2004): 1745-1749. Full Text
- Benjamin, DK, DeLong, E, Cotten, CM, Garges, HP, Steinbach, WJ, and Clark, RH. "Mortality following blood culture in premature infants: increased with Gram-negative bacteremia and candidemia, but not Gram-positive bacteremia." Journal of Perinatology : Official Journal of the California Perinatal Association 24, no. 3 (March 2004): 175-180. Full Text
- Benjamin, DK, DeLong, ER, Cotten, CM, Garges, HP, and Clark, RH. "Postconception age and other risk factors associated with mortality following Gram-negative rod bacteremia." J Perinatol 24, no. 3 (March 2004): 169-174. Full Text Link to Item
- Weintrob, AC, Hamilton, JD, Hahn, C, Klinzman, D, Moyo, G, Zdunek, D, Hess, G, Benjamin, DK, and Stapleton, JT. "Active or prior GB virus C infection does not protect against vertical transmission of HIV in coinfected women from Tanzania." Clinical Infectious Diseases: an Official Publication of the Infectious Diseases Society of America 38, no. 6 (March 2004): e46-e48. Full Text
- Miller, JL, Schell, WA, Wills, EA, Toffaletti, DL, Boyce, M, Benjamin, DK, Bartroli, J, and Perfect, JR. "In vitro and in vivo efficacies of the new triazole albaconazole against Cryptococcus neoformans." Antimicrobial Agents and Chemotherapy 48, no. 2 (February 2004): 384-387. Full Text
- Drew, RH, Dodds Ashley, E, Benjamin, DK, Duane Davis, R, Palmer, SM, and Perfect, JR. "Comparative safety of amphotericin B lipid complex and amphotericin B deoxycholate as aerosolized antifungal prophylaxis in lung-transplant recipients." Transplantation 77, no. 2 (January 27, 2004): 232-237. Full Text Link to Item
- Benjamin, DK, DeLong, E, and Steinbach, WJ. "Latent class analysis: an illustrative application for education in the assessment of resident otoscopic skills." Ambulatory Pediatrics : the Official Journal of the Ambulatory Pediatric Association 4, no. 1 (January 2004): 13-17. Full Text
- Benjamin, DK, Miller, WC, Ryder, RW, Weber, DJ, Walter, E, and McKinney, RE. "Growth patterns reflect response to antiretroviral therapy in HIV-positive infants: potential utility in resource-poor settings." Aids Patient Care and Stds 18, no. 1 (January 2004): 35-43. Full Text
- Benjamin, DK, Miro, JM, Hoen, B, Steinbach, WJ, Fowler, VG, Olaison, L, Habib, G, Abrutyn, E, Perfect, J, Zass, A, Corey, GR, Eykyn, S, Thuny, F, Jiménez-Expósito, M-J, Cabell, CH, and ICE-MD Study Group, . "Candida endocarditis: contemporary cases from the International Collaboration of Infectious Endocarditis Merged Database (ICE-mD)." Scandinavian Journal of Infectious Diseases 36, no. 6-7 (January 2004): 453-455. Full Text
- Benjamin, DK, Miller, WC, Ryder, RW, Weber, DJ, Walter, E, and McKinney, RE. "A comparison of height and weight velocity as a part of the composite endpoint in pediatric HIV." Aids (London, England) 17, no. 16 (November 2003): 2331-2336. Full Text
- Benjamin, DK, Garges, H, and Steinbach, WJ. "Candida bloodstream infection in neonates." Semin Perinatol 27, no. 5 (October 2003): 375-383. (Review) Link to Item
- Benjamin, DK, DeLong, ER, Steinbach, WJ, Cotton, CM, Walsh, TJ, and Clark, RH. "Empirical therapy for neonatal candidemia in very low birth weight infants." Pediatrics 112, no. 3 Pt 1 (September 2003): 543-547. Link to Item
- Benjamin, DK, DeLong, ER, Steinbach, WJ, Cotton, CM, Walsh, TJ, and Clark, RH. "Empirical therapy for neonatal candidemia in very low birth weight infants." Pediatrics 112, no. 3 I (September 1, 2003): 543-547. Full Text
- Benjamin, DK, Poole, C, Steinbach, WJ, Rowen, JL, and Walsh, TJ. "Neonatal candidemia and end-organ damage: a critical appraisal of the literature using meta-analytic techniques." Pediatrics 112, no. 3 Pt 1 (September 2003): 634-640. Full Text
- Weintrob, AC, Giner, J, Menezes, P, Patrick, E, Benjamin, DK, Lennox, J, Pilcher, CD, Eron, JJ, and Hicks, CB. "Infrequent diagnosis of primary human immunodeficiency virus infection: missed opportunities in acute care settings." Archives of Internal Medicine 163, no. 17 (September 2003): 2097-2100. Full Text
- Koeberl, DD, Young, SP, Gregersen, NS, Vockley, J, Smith, WE, Benjamin, DK, An, Y, Weavil, SD, Chaing, SH, Bali, D, McDonald, MT, Kishnani, PS, Chen, Y-T, and Millington, DS. "Rare disorders of metabolism with elevated butyryl- and isobutyryl-carnitine detected by tandem mass spectrometry newborn screening." Pediatric Research 54, no. 2 (August 2003): 219-223. Full Text
- Beaty, RM, Jackson, M, Peterson, D, Bird, A, Brown, T, Benjamin, DK, Juopperi, T, Kishnani, P, Boney, A, Chen, YT, and Koeberl, DD. "Delivery of glucose-6-phosphatase in a canine model for glycogen storage disease, type Ia, with adeno-associated virus (AAV) vectors." Gene Ther 9, no. 15 (August 2002): 1015-1022. Full Text Link to Item
- Fisher, RG, and Benjamin, DK. "Facial cellulitis in childhood: a changing spectrum." South Med J 95, no. 7 (July 2002): 672-674. Link to Item
- Steinbach, WJ, Sectish, TC, Benjamin, DK, Chang, KW, and Messner, AH. "Pediatric residents' clinical diagnostic accuracy of otitis media." Pediatrics 109, no. 6 (June 2002): 993-998. Link to Item
- Calland, JF, Adams, RB, Benjamin, DK, O'Connor, MJ, Chandrasekhara, V, Guerlain, S, and Jones, RS. "Thirty-day postoperative death rate at an academic medical center." Annals of Surgery 235, no. 5 (May 2002): 690-696. Full Text
- Benjamin, DK. "Integration of statistical theory and practical clinical expertise. Polymerase chain reaction testing of the HIV-exposed infant." Minerva Pediatr 54, no. 2 (April 2002): 105-111. (Review) Link to Item
- Dyke, CK, Benjamin, DK, Nelson, CL, Newby, K, O'shea, C, Cantor, W, Nguyen, C, Alexander, JH, Kitt, MM, and Tcheng, JE. "Elevated troponin following percutaneous coronary intervention predicts subsequent events: Results from the ESPRIT trial." JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 39, no. 5 (March 6, 2002): 72A-72A. Link to Item
- Benjamin, DK, Miller, WC, Bayliff, S, Martel, L, Alexander, KA, and Martin, PL. "Infections diagnosed in the first year after pediatric stem cell transplantation." Pediatr Infect Dis J 21, no. 3 (March 2002): 227-234. Link to Item
- Benjamin, DK, Miller, WC, Fiscus, SA, Benjamin, DK, Morse, M, Valentine, M, and McKinney, RE. "Rational testing of the HIV-exposed infant." Pediatrics 108, no. 1 (July 2001): E3-. Link to Item
- Benjamin, DK, Miller, W, Garges, H, McKinney, RE, Cotton, M, Fisher, RG, and Alexander, KA. "Bacteremia, central catheters, and neonates: when to pull the line." Pediatrics 107, no. 6 (June 2001): 1272-1276. Full Text
- Benjamin, DK, Ross, K, McKinney, RE, Benjamin, DK, Auten, R, and Fisher, RG. "When to suspect fungal infection in neonates: A clinical comparison of Candida albicans and Candida parapsilosis fungemia with coagulase-negative staphylococcal bacteremia." Pediatrics 106, no. 4 (October 2000): 712-718. Link to Item
- Benjamin, DK, Fisher, RG, McKinney, RE, and Benjamin, DK. "Candidal mycetoma in the neonatal kidney." Pediatrics 104, no. 5 Pt 1 (November 1999): 1126-1129. Link to Item
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Book Sections
- Zimmerman, K, and Benjamin, DK. "Necrotizing Enterocolitis." In Principles and Practice of Pediatric Infectious Diseases, 394-397.e2. June 21, 2017. Full Text
- Smyth, RL, Kaur, G, Benjamin, DK, and Laughon, MM. "Recruitment and Retention in Pediatric Clinical Trials: Focus on Pediatric Research Networks in the US and EU." In Pediatric Drug Development: Concepts and Applications, 455-471. January 1, 2013. Full Text
- Cotten, CM, and Benjamin, DK. "Necrotizing Enterocolitis." In Principles and Practice of Pediatric Infectious Diseases: Fourth Edition, 388-391.e2. August 30, 2012. Full Text
- Smith, PB, and Benjamin, DK. "Clinical Approach to the Infected Neonate." In Principles and Practice of Pediatric Infectious Diseases: Fourth Edition, 536-538.e1. August 30, 2012. Full Text
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Conference Papers
- Gerhart, JG, Watt, KM, Edginton, A, Wade, KC, Jr, BDK, Smith, PB, Hornik, CP, Cohen-Wolkowiez, M, Duara, S, Ross, AS, Shattuck, K, Stewart, DL, Neu, N, and Gonzalez, D. "PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODELING OF FLUCONAZOLE USING PLASMA AND CEREBROSPINAL FLUID SAMPLES COLLECTED FROM PRETERM AND TERM INFANTS." March 2018. Link to Item
- Ward, RM, Benjamin, D, Barrett, JS, Allegaert, K, Portman, R, Davis, JM, and Turner, MA. "Safety, dosing, and pharmaceutical quality for studies that evaluate medicinal products (including biological products) in neonates." May 2017. Full Text
- Watt, K, Cohen-Wolkowiez, M, Williams, D, Bonadonna, D, Cheifetz, I, Jr, BDK, and Brouwer, KL. "ANTIFUNGAL EXTRACTION BY THE EXTRACORPOREAL MEMBRANE OXYGENATION (ECMO) CIRCUIT EX VIVO." February 2015. Link to Item
- Yanni, SB, Smith, PB, Jr, BDK, Augustijns, P, Thakker, DR, and Annaert, P. "Age-Dependent Disposition of Micafungin in Humans: Effect of Serum Protein Binding." August 2010. Link to Item
- Baker-Smith, CM, Jr, BDK, Murphy, D, Eisenstein, EL, and Li, JS. "The economic return of performing pediatric anti-hypertensive drug clinical trials." October 16, 2007. Link to Item
- Li, JS, Smith, PB, Murphy, MD, Califf, RM, and Jr, BDK. "Racial differences in blood pressure response to angiotensin converting enzyme inhibitors in children: An analysis of 6 pediatric hypertension trials." October 16, 2007. Link to Item
- Benjamin, DK, DeLong, E, Cotten, CM, Garges, HP, Steinbach, WJ, and Clark, RH. "Mortality following blood culture in premature infants: Increased with Gram-negative bacteremia and candidemia, but not Gram-positive bacteremia." April 2004. Link to Item
- Tiffany, KF, Benjamin, DK, O'Donnell, KJ, and Gutman, LT. "Improved neuro-developmental outcomes following long-term suppressive oral acyclovir in infants with disseminated/encephalitic herpes simplex disease." April 2004. Link to Item
- Benjamin, DK, Delong, ER, Steinbach, WJ, Cotten, CM, Walsh, TJ, and Clark, RH. "Empirical therapy for neonatal candidemia: Evaluation of 21,233 blood cultures." April 2003. Link to Item
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