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Daphne Ruth Friedman

Medical Professor in the Department of Medicine
Medicine, Medical Oncology
508 Fulton Street (111G), Durham, NC 27705
508 Fulton Street (111G), Durham VA Medical Center, Durham, NC 27705

Overview


My area of expertise is in leukemias and lymphomas, including Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma. My research interests are focused on improving treatment options for patients with hematologic malignancies, through laboratory and clinical research.  I am also a staff physician at the Durham VA Medical Center, and am deeply committed to expanding treatment options for veterans, including working on clinical trials for multiple myeloma, prostate cancer, and lung cancer at the Durham VA.

Current Duke Appointments & Affiliations


Medical Professor in the Department of Medicine · 2026 - Present Medicine, Medical Oncology, Medicine
Member of the Duke Cancer Institute · 2013 - Present Duke Cancer Institute, Institutes and Centers

Recent Scholarly Works


Association Between Monoclonal Gammopathy of Undetermined Significance and Cardiovascular Disease Risk: A Veterans Health Administration Study.

Journal article J Am Heart Assoc · January 6, 2026 BACKGROUND: Monoclonal gammopathy of undetermined significance (MGUS) is associated with an increased risk of cardiovascular disease (CVD). However, its potential to provide additional prognostic information beyond traditional CVD risk assessments remains ... Full text Link to item Cite

Cancer decentralized clinical trials in the Veterans Health Administration.

Journal article J Natl Cancer Inst · January 1, 2026 BACKGROUND: Despite the importance of clinical trials in the advancement of cancer treatments, there are barriers to participant enrollment. Decentralized clinical trials are conducted at a different physical location than where patients receive medical ca ... Full text Link to item Cite

Rule-based natural language processing to extract clinical trial and research study enrollment history from unstructured notes.

Journal article Health Informatics J · 2026 Clinical trials are vital for advancing care. However, a systematic approach to tracking trial participation across different facilities and sponsors has been lacking. We developed natural language processing (NLP) methods to extract study enrollment histo ... Full text Link to item Cite
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Recent Grants


The Duke University - Duke Cancer Institute National Clinical Trials Network Lead Academic Participating Site (UG1) Support Grant

ResearchSignificant Contributor · Awarded by National Institutes of Health · 2019 - 2032

Experience of Veterans with Myeloproliferative Neoplasms

ResearchCo-Mentor · Awarded by American Society of Clinical Oncology · 2025 - 2026

View All Grants

Education


University of Maryland, College Park · 2002 M.D.