Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Fellowship in Gastroenterology and Hepatology, Beth Israel Deaconess Medical Center 2015 - 2017
  • Chief Medical Resident in Medicine, Beth Israel Deaconess Medical Center 2014 - 2015
  • Internal Medicine Residency, Beth Israel Deaconess Medical Center 2010 - 2013
  • M.D., Stony Brook University, Renaissance School of Medicine 2010
• 

  Previous Appointments & Affiliations

  • Assistant Professor of Medicine, Medicine, Gastroenterology, Medicine 2017 - 2020
• Research
• 

  Selected Grants

  • Observational Study Assessing for Effect of CREON on Symptoms of Exocrine Pancreatic Insufficiency (EPI) in Patients with EPI due to Chronic Pancreatitis (CP) awarded by AbbVie Inc. 2022 - 2025
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • O’Connell, Brendon, Amanda Boyd, Darshan Kothari, Neena Miller, Jennifer Cornejo, and Brian Sullivan. “Improving documentation of anticoagulation and antiplatelet recommendations after outpatientendoscopy.” Bmj Open Qual 11, no. 4 (December 2022). https://doi.org/10.1136/bmjoq-2021-001725.
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    • Shah, Ishani, Rachel Bocchino, Awais Ahmed, Steven D. Freedman, Darshan J. Kothari, and Sunil G. Sheth. “Impact of recurrent acute pancreatitis on the natural history and progression to chronic pancreatitis.” Pancreatology 22, no. 8 (December 2022): 1084–90. https://doi.org/10.1016/j.pan.2022.09.237.
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    • Shah, Ishani, Rachel Bocchino, William Yakah, Awais Ahmed, Steven D. Freedman, Darshan J. Kothari, and Sunil G. Sheth. “Evaluating Outcomes and Misuse in Opioid-Dependent Chronic Pancreatitis Using a State-Mandated Monitoring System.” Dig Dis Sci 67, no. 12 (December 2022): 5493–99. https://doi.org/10.1007/s10620-022-07459-y.
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    • Zuberi, Shaharyar A., Ishani Shah, Rachel L. Bocchino, Awais Ahmed, Steven D. Freedman, Darshan J. Kothari, and Sunil G. Sheth. “Pre-existing, Concurrent/Early-Onset, and Late-Onset Diabetes in Chronic Pancreatitis: Do Outcomes Differ?” Dig Dis Sci, November 1, 2022. https://doi.org/10.1007/s10620-022-07742-y.
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    • Sorrento, Cristina, Ishani Shah, William Yakah, Awais Ahmed, Supisara Tintara, Cinthana Kandasamy, Steven D. Freedman, Darshan J. Kothari, and Sunil G. Sheth. “Inpatient Alcohol Cessation Counseling Is Associated With a Lower 30-Day Hospital Readmission in Acute Alcoholic Pancreatitis.” J Clin Gastroenterol 56, no. 9 (October 1, 2022): e313–17. https://doi.org/10.1097/MCG.0000000000001666.
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    • Donnangelo, Lauren L., Brijen J. Shah, and Darshan J. Kothari. “Disclosure and Reflection After an Adverse Event: Tips for Training and Practice.” Gastroenterology 163, no. 3 (September 2022): 568–71. https://doi.org/10.1053/j.gastro.2022.07.003.
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    • Tintara, Supisara, Ishani Shah, William Yakah, John J. Kowalczyk, Cristina Sorrento, Cinthana Kandasamy, Awais Ahmed, Steven D. Freedman, Darshan J. Kothari, and Sunil G. Sheth. “Comparison of Opioid-Based Patient-Controlled Analgesia with Physician-Directed Analgesia in Acute Pancreatitis: A Retrospective Cohort Study.” Dig Dis Sci, June 6, 2022. https://doi.org/10.1007/s10620-022-07573-x.
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    • Tintara, Supisara, Ishani Shah, William Yakah, Awais Ahmed, Cristina S. Sorrento, Cinthana Kandasamy, Steven D. Freedman, Darshan J. Kothari, and Sunil G. Sheth. “Evaluating the accuracy of American Society for Gastrointestinal Endoscopy guidelines in patients with acute gallstone pancreatitis with choledocholithiasis.” World J Gastroenterol 28, no. 16 (April 28, 2022): 1692–1704. https://doi.org/10.3748/wjg.v28.i16.1692.
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    • Kandasamy, Cinthana, Ishani Shah, William Yakah, Awais Ahmed, Supisara Tintara, Cristina Sorrento, Steven D. Freedman, Darshan J. Kothari, and Sunil G. Sheth. “The Impact of an Inpatient Pancreatitis Service and Educational Intervention Program on the Outcome of Acute Pancreatitis.” The American Journal of Medicine 135, no. 3 (March 2022): 350-359.e2. https://doi.org/10.1016/j.amjmed.2021.09.021.
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    • Shah, Ishani, William Yakah, Awais Ahmed, Cinthana Kandasamy, Supisara Tintara, Cristina Sorrento, Steven D. Freedman, Darshan J. Kothari, and Sunil G. Sheth. “Extrapancreatic Complications in Hospitalized Patients With Mild Acute Pancreatitis Are Associated With Poorer Outcomes: Results From a Single-Center Study.” Pancreas 51, no. 2 (February 1, 2022): 177–82. https://doi.org/10.1097/MPA.0000000000001986.
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    • Shah, Ishani, Sunil G. Sheth, and Darshan J. Kothari. “Pain management in chronic pancreatitis incorporating safe opioid practices: Challenge accepted.” World J Gastroenterol 27, no. 23 (June 21, 2021): 3142–47. https://doi.org/10.3748/wjg.v27.i23.3142.
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    • Ahmed, Awais, Jason C. Fisher, Mark B. Pochapin, Steven D. Freedman, Darshan J. Kothari, Paresh C. Shah, and Sunil G. Sheth. “Hyperlipasemia in absence of acute pancreatitis is associated with elevated D-dimer and adverse outcomes in COVID 19 disease.” Pancreatology 21, no. 4 (June 2021): 698–703. https://doi.org/10.1016/j.pan.2021.02.021.
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    • Wall, April, and Darshan Kothari. “Patient Safety Reporting in GI: All Hands on Deck.” Clin Gastroenterol Hepatol 19, no. 4 (April 2021): 629-632.e1. https://doi.org/10.1016/j.cgh.2020.11.007.
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    • Ahmed, Awais, Darshan J. Kothari, Scott Wardlaw, Steven D. Freedman, and Sunil G. Sheth. “Reducing Hospitalization in Mild Acute Pancreatitis: Results of Long-term Follow-up.” J Clin Gastroenterol 55, no. 2 (February 1, 2021): 180–86. https://doi.org/10.1097/MCG.0000000000001354.
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    • Lee, Tzu-Hao, Cecelia Zhang, Richard Wood, and Darshan Kothari. “C.O.V.I.D.: A Survival Guide for GI Fellowship Training During the COVID-19 Pandemic.” Clin Gastroenterol Hepatol 19, no. 1 (January 2021): 6–9. https://doi.org/10.1016/j.cgh.2020.10.001.
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    • Kothari, Darshan J., and Sunil G. Sheth. “Opportunity Is Knocking: Brainstorming Neural Networks for Management of Acute Pancreatitis.” Pancreas 50, no. 1 (January 1, 2021): e11–13. https://doi.org/10.1097/MPA.0000000000001716.
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    • Ahmed, Awais, William Yakah, Steven D. Freedman, Darshan J. Kothari, and Sunil G. Sheth. “Evaluation of Opioid Use in Acute Pancreatitis in Absence of Chronic Pancreatitis: Absence of Opioid Dependence an Important Feature.” Am J Med 133, no. 10 (October 2020): 1209–18. https://doi.org/10.1016/j.amjmed.2020.03.010.
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    • Ahmed, Awais, Aman Deep, Darshan J. Kothari, and Sunil G. Sheth. “Bone disease in chronic pancreatitis.” World J Clin Cases 8, no. 9 (May 6, 2020): 1574–79. https://doi.org/10.12998/wjcc.v8.i9.1574.
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    • Kothari, Darshan, and Sunil G. Sheth. “Treating Acute Medical Conditions Outside the Hospital: Streamlining Care During a Pandemic.” J Clin Gastroenterol 54, no. 10 (2020): 912–13. https://doi.org/10.1097/MCG.0000000000001427.
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    • Kothari, Darshan, Matthew Babineau, Matthew Hall, Steven D. Freedman, Nathan I. Shapiro, and Sunil G. Sheth. “Preventing Hospitalization in Mild Acute Pancreatitis Using a Clinical Pathway in the Emergency Department.” J Clin Gastroenterol 52, no. 8 (September 2018): 734–41. https://doi.org/10.1097/MCG.0000000000000954.
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    • Kothari, D., M. R. Struyvenberg, M. C. Perillo, G. Ezaz, S. D. Freedman, and S. G. Sheth. “Extra-pancreatic complications, especially hemodialysis predict mortality and length of stay, in ICU patients admitted with acute pancreatitis.” Gastroenterology Report 6, no. 3 (August 1, 2018): 202–9. https://doi.org/10.1093/gastro/goy005.
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    • Paulson, Erik Karl, and Darshan Kothari. “Re: "Management of Incidental Pancreatic Cysts: A White Paper of the ACR Incidental Findings Committee".” J Am Coll Radiol 15, no. 4 (April 2018): 591. https://doi.org/10.1016/j.jacr.2017.11.016.
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    • Kothari, Darshan, Gyanprakash Ketwaroo, Steven D. Freedman, and Sunil G. Sheth. “The Impact of Risk Factors of Chronic Pancreatitis on Secretin Pancreatic Function Testing: Results of a 20-Year Study.” Pancreas 46, no. 7 (August 2017): 887–90. https://doi.org/10.1097/MPA.0000000000000871.
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    • Kothari, Darshan, Gyanprakash Ketwaroo, Mandeep S. Sawhney, Steven D. Freedman, and Sunil G. Sheth. “Comparison of Combined Endoscopic Ultrasonography and Endoscopic Secretin Testing With the Traditional Secretin Pancreatic Function Test in Patients With Suspected Chronic Pancreatitis: A Prospective Crossover Study.” Pancreas 46, no. 6 (July 2017): 770–75. https://doi.org/10.1097/MPA.0000000000000829.
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    • Kothari, D., J. D. Feuerstein, L. Moss, J. D’Souza, K. Montanaro, D. A. Leffler, and S. G. Sheth. “An open-access endoscopy screen correctly and safely identifies patients for conscious sedation.” Gastroenterology Report 4, no. 4 (November 1, 2016): 281–86. https://doi.org/10.1093/gastro/gow020.
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    • Gianotti, Robert J., Sveta Shah Oza, Elliot B. Tapper, Darshan Kothari, and Sunil G. Sheth. “A Longitudinal Study of Adenoma Detection Rate in Gastroenterology Fellowship Training.” Dig Dis Sci 61, no. 10 (October 2016): 2831–37. https://doi.org/10.1007/s10620-016-4228-9.
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    • Mueller, Jessica L., Lindsay Y. King, Kara B. Johnson, Tian Gao, Lauren D. Nephew, Darshan Kothari, Mary Ann Simpson, et al. “Impact of EGF, IL28B, and PNPLA3 polymorphisms on the outcome of allograft hepatitis C: a multicenter study.” Clin Transplant 30, no. 4 (April 2016): 452–60. https://doi.org/10.1111/ctr.12710.
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    • Patwardhan, Vilas R., Joseph D. Feuerstein, Neil Sengupta, Jeffrey J. Lewandowski, Roy Tsao, Darshan Kothari, Harry T. Anastopoulos, Richard B. Doyle, Daniel A. Leffler, and Sunil G. Sheth. “Fellowship Colonoscopy Training and Preparedness for Independent Gastroenterology Practice.” J Clin Gastroenterol 50, no. 1 (January 2016): 45–51. https://doi.org/10.1097/MCG.0000000000000376.
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    • Grunwald, Douglas, Darshan Kothari, and Raza Malik. “Noninvasive markers in the assessment and management of autoimmune liver diseases.” Eur J Gastroenterol Hepatol 26, no. 10 (October 2014): 1065–72. https://doi.org/10.1097/MEG.0000000000000176.
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    • Cohen, J., E. Hariton, D. Kothari, G. A. Pihan, and S. C. Robson. “Hepatosplenic alpha/beta T-cell lymphoma masquerading as cirrhosis.” Journal of Gastrointestinal Oncology 4, no. 2 (January 1, 2013): 131–36. https://doi.org/10.3978/j.issn.2078-6891.2013.017.
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  • Conference Papers

    • Nama, N., A. M. Hein, S. Au, J. Gloria, C. M. Richman, A. Parish, D. Niedzwiecki, A. M. Johnson, J. P. Spaete, and D. Kothari. “Same Admission Cholecystectomy for Patients Admitted With Acute Gallstone Pancreatitis: Testing a Hospital Based Quality Metric.” In Pancreas, 50:1085–1085, 2021.
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    • Cook, Hannah E., Rachel B. Britt, Mohamed Hashem, Sara R. Britnell, Vera Pervitsky, and Darshan Kothari. “Assessment of Pancrelipase Utilization Within a Veterans Affairs Health Care System.” In American Journal of Gastroenterology, 115:S54–S54, 2020.
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    • Lee, Tzu-Hao, Lindsay King, Amit Patel, Cecelia Zhang, Yuval A. Patel, and Darshan Kothari. “Education Innovation During COVID-19 Pandemic: Using an Interactive Instant Message Application to Enhance GI Fellowship Education.” In American Journal of Gastroenterology, 115:S622–23, 2020.
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