David Harold Harpole Jr.

David Harold Harpole Jr.
Professor of Surgery

A. Non-small cell lung cancer
1. Evaluation of serum and tissue molecular biologic markers of recurrence in patients with a localize non-small cell lung cancer.
2. Molecular biologic staging of lymph nodes in patients with non-small cell lung cancer.
3. The evaluation of the clonality of metastatic tumors in patients with non-small cell lung cancer.

B. Clinical research activities
1. Creation of a prospective database for the Duke Thoracic Oncology Program.
2. A cost and satisfaction evaluation of thoracoscopy and open thoracotomy in patients.
3. Development of risk associated models of morbidity in patients undergoing general thoracic surgery procedures: The VA Cooperative Surgical Risk Study
4. A member of the Duke Gastrointestinal Malignancy Research Committee, developing esophageal cancer treatment protocols and outcome studies.

Current Appointments & Affiliations

Professor of Surgery, Surgery, Cardiovascular and Thoracic Surgery, Surgery 2003
Associate Professor in Pathology, Pathology, Clinical Science Departments 2005
Professor in Pathology, Pathology, Clinical Science Departments 2018
Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 1987

Contact Information

Box 3627 Med Ctr, Durham, NC 27710
Hock Plaza-2424 Erwin Rd, Suite 403 Room 4017, Durham, NC 27705
david.harpole@duke.edu (919) 668-8413

Background
Education, Training, & Certifications
- Instructor of Surgery, Surgery, Harvard University - 1996
- M.D., University of Virginia 1984
Duke Appointment History
- Assistant Professor of Pathology, Pathology, Clinical Science Departments 2000 - 2005
- Associate Professor of Surgery, Surgery, Cardiovascular and Thoracic Surgery, Surgery 2000 - 2003
- Assistant Clinical Professor of Pathology, Pathology, Clinical Science Departments 1997 - 2000
- Associate Professor of Surgery, Surgery, Cardiovascular and Thoracic Surgery, Surgery 1997 - 2000
- Associate Clinical Professor of Surgery, Surgery, Cardiovascular and Thoracic Surgery, Surgery 1996 - 1997
- Instructor, Temporary in the Department of Surgery, Surgery, Cardiovascular and Thoracic Surgery, Surgery 1996
Research
Selected Grants
- Duke Resident Physician-Scientist Program - NIAID awarded by National Institutes of Health 2018 - 2022
- Duke Resident Physician-Scientist Program- NHLBI awarded by National Institutes of Health 2018 - 2022
- Translational Research in Surgical Oncology awarded by National Institutes of Health 2002 - 2021
- Prospective Validation of Prognostic and Predictive Molecular tests in Mesothelioma awarded by Brigham and Women's Hospital 2017 - 2021
- Military Exposure-Related Pleural Mesothelioma: An Innovative Translational Approach to Inform Novel Molecular-Targeted Treatment Development awarded by Department of Defense 2017 - 2021
- A Retrospective Study of the myPlan Lung Cancer Test and Prediction of Chemotherapy Benefit in Patients with Early Stage Lung Adenocarcinoma awarded by Myriad Genetics, Inc. 2016 - 2021
- IPA for Tracey Taylor awarded by Durham Veterans Affairs Medical Center 2018 - 2020
- Elucidating the Genome of Large Cell Lung Neuroendocrine Cancer awarded by Thoracic Surgery Foundation for Research and Education 2019 - 2020
- Lung Squamous Cell Carcinoma: Validation of Molecular Signatures of Prognosis awarded by University of Colorado - Denver 2012 - 2017
- Clinical Oncology Research Career Development Program awarded by National Institutes of Health 2009 - 2015
- GSK2302032A Antigen-Specific cancer Immunotherapeutic as adjuvant therapy in patients with Non-Small Cell Lung Cancer awarded by GlaxoSmithKline 2013 - 2015
- IPA - Joshi awarded by Veterans Administration Medical Center 2011 - 2013
- IPA - Debbie Conlon awarded by Durham Veterans Affairs Medical Center 2012 - 2013
- Validating Molecular Signature Risk Models of NSCLC awarded by National Institutes of Health 2006 - 2012
- Refining and Validating Genomic Signatures in Lung Cancer awarded by National Institutes of Health 2009 - 2010
- Prospective Validation of Genomic Signatures of Chemosensitivity in NSCLC awarded by National Institutes of Health 2009 - 2010
- Semiparametric ROC Curve Regression for Cancer Screening Studies awarded by National Institutes of Health 2007 - 2010
- Tissue and serum indicators of lung cancer recurrence. awarded by National Institutes of Health 1996 - 2002
- Tissue And Serum Indicators Of Lung Cancer Recurrence awarded by National Institutes of Health 1996 - 1999
External Relationships
- AstraZeneca
- Medtronic (Covidien)
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Farrow, Norma E., Vignesh Raman, Oliver K. Jawitz, Soraya L. Voigt, Betty C. Tong, David H. Harpole, and Thomas A. D’Amico. “Impact of Age on Surgical Outcomes for Locally Advanced Esophageal Cancer.” Ann Thorac Surg 111, no. 3 (March 2021): 996–1003. https://doi.org/10.1016/j.athoracsur.2020.06.055.
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  - Rhodin, Kristen E., Vignesh Raman, Oliver K. Jawitz, Soraya L. Voigt, Norma E. Farrow, David H. Harpole, Betty C. Tong, and Thomas A. D’Amico. “Patterns of Use of Induction Therapy for T2N0 Esophageal Cancer.” Ann Thorac Surg 111, no. 2 (February 2021): 440–47. https://doi.org/10.1016/j.athoracsur.2020.05.089.
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  - Raman, Vignesh, Oliver K. Jawitz, Soraya L. Voigt, Kristen E. Rhodin, Thomas A. D’Amico, David H. Harpole, Chi-Fu Jeffrey Yang, and Betty C. Tong. “The Effect of Tumor Size and Histologic Findings on Outcomes After Segmentectomy vs Lobectomy for Clinically Node-Negative Non-Small Cell Lung Cancer.” Chest 159, no. 1 (January 2021): 390–400. https://doi.org/10.1016/j.chest.2020.06.066.
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  - Raman, Vignesh, Oliver K. Jawitz, Soraya L. Voigt, Kristen E. Rhodin, Anthony W. Kim, Betty C. Tong, Thomas A. D’Amico, and David H. Harpole. “Patterns of Care in Neoadjuvant Chemoradiotherapy for Node-Positive Esophageal Adenocarcinoma.” Ann Thorac Surg 110, no. 6 (December 2020): 1832–39. https://doi.org/10.1016/j.athoracsur.2020.05.069.
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  - Rucker, A Justin, Vignesh Raman, Oliver K. Jawitz, Soraya L. Voigt, Betty C. Tong, Thomas A. D’Amico, and David H. Harpole. “Effect of Lymph Node Assessment on Outcomes in Surgery for Limited Stage Small Cell Lung Cancer.” Ann Thorac Surg 110, no. 6 (December 2020): 1854–60. https://doi.org/10.1016/j.athoracsur.2020.04.117.
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  - Bueno, Raphael, William G. Richards, David H. Harpole, Karla V. Ballman, Ming-Sound Tsao, Zhengming Chen, Xiaofei Wang, et al. “Multi-Institutional Prospective Validation of Prognostic mRNA Signatures in Early Stage Squamous Lung Cancer (Alliance).” J Thorac Oncol 15, no. 11 (November 2020): 1748–57. https://doi.org/10.1016/j.jtho.2020.07.005.
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  - Voigt, Soraya L., Vignesh Raman, Oliver K. Jawitz, Muath Bishawi, Chi-Fu Jeffrey Yang, Betty C. Tong, Thomas A. D’Amico, and David H. Harpole. “The Role of Neoadjuvant Chemotherapy in Patients With Resectable Malignant Pleural Mesothelioma-An Institutional and National Analysis.” J Natl Cancer Inst 112, no. 11 (November 1, 2020): 1118–27. https://doi.org/10.1093/jnci/djaa002.
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  - Ganesh, Arun, Yawar J. Qadri, Richard L. Boortz-Marx, Sana M. Al-Khatib, David H. Harpole, Jason N. Katz, Jason I. Koontz, et al. “Stellate Ganglion Blockade: an Intervention for the Management of Ventricular Arrhythmias.” Curr Hypertens Rep 22, no. 12 (October 23, 2020): 100. https://doi.org/10.1007/s11906-020-01111-8.
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  - Rhodin, Kristen E., Vignesh Raman, Oliver K. Jawitz, Betty C. Tong, David H. Harpole, and Thomas A. D’Amico. “The Effect of Timing of Adjuvant Therapy on Survival After Esophagectomy.” Ann Thorac Surg 110, no. 3 (September 2020): 1023–29. https://doi.org/10.1016/j.athoracsur.2020.03.040.
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  - Mayne, Nicholas R., Alice J. Darling, Vignesh Raman, Scott Balderson, Mark F. Berry, David H. Harpole, Thomas A. D’Amico, and Chi-Fu Jeffrey Yang. “Perioperative Outcomes and 5-year Survival After Open versus Thoracoscopic Sleeve Resection for Lung Cancer.” Semin Thorac Cardiovasc Surg, August 25, 2020. https://doi.org/10.1053/j.semtcvs.2020.08.013.
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  - Nobuhara, Chloe K., W Michael Bullock, Thomas Bunning, Brian Colin, Mary Cooter, Michael J. Devinney, Michael N. Ferrandino, et al. “A protocol to reduce self-reported pain scores and adverse events following lumbar punctures in older adults.” J Neurol 267, no. 7 (July 2020): 2002–6. https://doi.org/10.1007/s00415-020-09797-1.
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  - Fudim, Marat, Yawar J. Qadri, Nathan H. Waldron, Richard L. Boortz-Marx, Arun Ganesh, Chetan B. Patel, Mihai V. Podgoreanu, et al. “Stellate Ganglion Blockade for the Treatment of Refractory Ventricular Arrhythmias.” Jacc Clin Electrophysiol 6, no. 5 (May 2020): 562–71. https://doi.org/10.1016/j.jacep.2019.12.017.
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  - Raman, Vignesh, Oliver K. Jawitz, Chi-Fu J. Yang, Soraya L. Voigt, Anthony W. Kim, Betty C. Tong, Thomas A. D’Amico, and David H. Harpole. “The influence of adjuvant therapy on survival in patients with indeterminate margins following surgery for non-small cell lung cancer.” J Thorac Cardiovasc Surg 159, no. 5 (May 2020): 2030-2040.e4. https://doi.org/10.1016/j.jtcvs.2019.09.075.
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  - Raman, Vignesh, Oliver K. Jawitz, Soraya L. Voigt, Chi-Fu J. Yang, Thomas A. D’Amico, and David H. Harpole. “The Role of Adjuvant Therapy in Patients With Margin-Positive (R1) Esophagectomy: A National Analysis.” J Surg Res 249 (May 2020): 82–90. https://doi.org/10.1016/j.jss.2019.11.035.
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  - Raman, Vignesh, Oliver K. Jawitz, Soraya L. Voigt, Chi-Fu J. Yang, Hanghang Wang, David H. Harpole, and Thomas A. D’Amico. “Effect of time to surgery on outcomes in stage I esophageal adenocarcinoma.” J Thorac Cardiovasc Surg 159, no. 4 (April 2020): 1626-1635.e1. https://doi.org/10.1016/j.jtcvs.2019.09.123.
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  - Rucker, A Justin, Vignesh Raman, Oliver K. Jawitz, Soraya L. Voigt, David H. Harpole, Thomas A. D’Amico, and Betty C. Tong. “The Impact of Adjuvant Therapy on Survival After Esophagectomy for Node-negative Esophageal Adenocarcinoma.” Ann Surg, March 20, 2020. https://doi.org/10.1097/SLA.0000000000003886.
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  - Raman, Vignesh, Oliver K. Jawitz, Chi-Fu J. Yang, Soraya L. Voigt, Betty C. Tong, Thomas A. D’Amico, and David H. Harpole. “Outcomes for Surgery in Large Cell Lung Neuroendocrine Cancer.” J Thorac Oncol 14, no. 12 (December 2019): 2143–51. https://doi.org/10.1016/j.jtho.2019.09.005.
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  - Raman, Vignesh, Oliver K. Jawitz, Chi-Fu J. Yang, Soraya L. Voigt, Hanghang Wang, Thomas A. D’Amico, David H. Harpole, and Betty C. Tong. “Outcomes of surgery versus chemoradiotherapy in patients with clinical or pathologic stage N3 non-small cell lung cancer.” J Thorac Cardiovasc Surg 158, no. 6 (December 2019): 1680-1692.e2. https://doi.org/10.1016/j.jtcvs.2019.08.033.
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  - Raman, Vignesh, Oliver K. Jawitz, Soraya L. Voigt, Norma E. Farrow, Chi-Fu J. Yang, Thomas A. D’Amico, and David H. Harpole. “Surgery Is Associated With Survival Benefit in T4a Esophageal Adenocarcinoma: A National Analysis.” Ann Thorac Surg 108, no. 6 (December 2019): 1633–39. https://doi.org/10.1016/j.athoracsur.2019.05.091.
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  - Berger, Miles, David M. Murdoch, Janet S. Staats, Cliburn Chan, Jake P. Thomas, Grant E. Garrigues, Jeffrey N. Browndyke, et al. “Flow Cytometry Characterization of Cerebrospinal Fluid Monocytes in Patients With Postoperative Cognitive Dysfunction: A Pilot Study.” Anesth Analg 129, no. 5 (November 2019): e150–54. https://doi.org/10.1213/ANE.0000000000004179.
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  - Gill, Ritu R., Anne S. Tsao, Hedy L. Kindler, William G. Richards, Samuel G. Armato, Roslyn J. Francis, Daniel R. Gomez, et al. “Radiologic Considerations and Standardization of Malignant Pleural Mesothelioma Imaging Within Clinical Trials: Consensus Statement from the NCI Thoracic Malignancy Steering Committee - International Association for the Study of Lung Cancer - Mesothelioma Applied Research Foundation Clinical Trials Planning Meeting.” J Thorac Oncol 14, no. 10 (October 2019): 1718–31. https://doi.org/10.1016/j.jtho.2019.08.012.
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  - Tsao, Ming-Sound, Michele Carbone, Francoise Galateau-Salle, Andre L. Moreira, Andrew G. Nicholson, Anja C. Roden, Alex A. Adjei, et al. “Pathologic Considerations and Standardization in Mesothelioma Clinical Trials.” J Thorac Oncol 14, no. 10 (October 2019): 1704–17. https://doi.org/10.1016/j.jtho.2019.06.020.
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  - Friedberg, Joseph S., Melissa J. Culligan, Anne S. Tsao, Valerie Rusch, Boris Sepesi, Harvey I. Pass, Raphael Bueno, et al. “A Proposed System Toward Standardizing Surgical-Based Treatments for Malignant Pleural Mesothelioma, From the Joint National Cancer Institute-International Association for the Study of Lung Cancer-Mesothelioma Applied Research Foundation Taskforce.” J Thorac Oncol 14, no. 8 (August 2019): 1343–53. https://doi.org/10.1016/j.jtho.2019.04.029.
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  - Raman, Vignesh, Oliver K. Jawitz, Chi-Fu J. Yang, Betty C. Tong, Thomas A. D’Amico, Mark F. Berry, and David H. Harpole. “Adjuvant Therapy for Patients With Early Large Cell Lung Neuroendocrine Cancer: A National Analysis.” Ann Thorac Surg 108, no. 2 (August 2019): 377–83. https://doi.org/10.1016/j.athoracsur.2019.03.053.
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  - Gomez, Daniel R., Andreas Rimner, Charles B. Simone, BC John Cho, Marc de Perrot, Alex A. Adjei, Raphael Bueno, et al. “The Use of Radiation Therapy for the Treatment of Malignant Pleural Mesothelioma: Expert Opinion from the National Cancer Institute Thoracic Malignancy Steering Committee, International Association for the Study of Lung Cancer, and Mesothelioma Applied Research Foundation.” J Thorac Oncol 14, no. 7 (July 2019): 1172–83. https://doi.org/10.1016/j.jtho.2019.03.030.
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  - Klinger, Rebecca Y., Mary Cooter, Tiffany Bisanar, Niccolò Terrando, Miles Berger, Mihai V. Podgoreanu, Mark Stafford-Smith, Mark F. Newman, Joseph P. Mathew, and Joseph P. Neurologic Outcomes Research Group of the Duke Heart Center. “Intravenous Lidocaine Does Not Improve Neurologic Outcomes after Cardiac Surgery: A Randomized Controlled Trial.” Anesthesiology 130, no. 6 (June 2019): 958–70. https://doi.org/10.1097/ALN.0000000000002668.
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  - Berger, Miles, Deborah Oyeyemi, Mobolaji O. Olurinde, Heather E. Whitson, Kent J. Weinhold, Marty G. Woldorff, Lewis A. Lipsitz, et al. “The INTUIT Study: Investigating Neuroinflammation Underlying Postoperative Cognitive Dysfunction.” J Am Geriatr Soc 67, no. 4 (April 2019): 794–98. https://doi.org/10.1111/jgs.15770.
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  - Barac, Yaron D., David Harold Harpole, Kamrouz Ghadimi, and Carmelo A. Milano. “A One-Step Autotransplantation Can Facilitate the Excision of Cardiac Tumors Invading the Lung.” Semin Thorac Cardiovasc Surg 31, no. 3 (2019): 475–76. https://doi.org/10.1053/j.semtcvs.2019.01.012.
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  - Yang, Chi-Fu Jeffrey, Arvind Kumar, Jacob A. Klapper, Matthew G. Hartwig, Betty C. Tong, David H. Harpole, Mark F. Berry, and Thomas A. D’Amico. “A National Analysis of Long-term Survival Following Thoracoscopic Versus Open Lobectomy for Stage I Non-small-cell Lung Cancer.” Ann Surg 269, no. 1 (January 2019): 163–71. https://doi.org/10.1097/SLA.0000000000002342.
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  - Yu, Hui, Zhengming Chen, Karla V. Ballman, Mark A. Watson, Ramaswamy Govindan, Irena Lanc, David G. Beer, et al. “Correlation of PD-L1 Expression with Tumor Mutation Burden and Gene Signatures for Prognosis in Early-Stage Squamous Cell Lung Carcinoma.” J Thorac Oncol 14, no. 1 (January 2019): 25–36. https://doi.org/10.1016/j.jtho.2018.09.006.
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  - Crowson, Matthew G., Betty C. Tong, Hui-Jie Lee, Yao Song, David H. Harpole, Harrison N. Jones, and Seth Cohen. “Prevalence and resource utilization for vocal fold paralysis/paresis after esophagectomy.” Laryngoscope 128, no. 12 (December 2018): 2815–22. https://doi.org/10.1002/lary.27252.
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  - Yang, Chi-Fu Jeffrey, Derek Y. Chan, Shivani A. Shah, Babatunde A. Yerokun, Xiaofei F. Wang, Thomas A. D’Amico, Mark F. Berry, and David H. Harpole. “Long-term Survival After Surgery Compared With Concurrent Chemoradiation for Node-negative Small Cell Lung Cancer.” Ann Surg 268, no. 6 (December 2018): 1105–12. https://doi.org/10.1097/SLA.0000000000002287.
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  - Tsao, Anne S., O Wolf Lindwasser, Alex A. Adjei, Prasad S. Adusumilli, Matthew L. Beyers, Gideon M. Blumenthal, Raphael Bueno, et al. “Current and Future Management of Malignant Mesothelioma: A Consensus Report from the National Cancer Institute Thoracic Malignancy Steering Committee, International Association for the Study of Lung Cancer, and Mesothelioma Applied Research Foundation.” J Thorac Oncol 13, no. 11 (November 2018): 1655–67. https://doi.org/10.1016/j.jtho.2018.08.2036.
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  - Hodapp, Dorothee, Elizabeth T. Borer, W Stanley Harpole, Eric M. Lind, Eric W. Seabloom, Peter B. Adler, Juan Alberti, et al. “Spatial heterogeneity in species composition constrains plant community responses to herbivory and fertilisation.” Ecol Lett 21, no. 9 (September 2018): 1364–71. https://doi.org/10.1111/ele.13102.
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  - Yang, Chi-Fu Jeffrey, Kelli Aibel, Ryan Meyerhoff, Frances Wang, David Harpole, Amy P. Abernethy, and Thomas W. LeBlanc. “Actigraphy assessment of sleep quality among patients with acute myeloid leukaemia during induction chemotherapy.” Bmj Support Palliat Care 8, no. 3 (September 2018): 274–77. https://doi.org/10.1136/bmjspcare-2018-001509.
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  - Anderson, T Michael, Daniel M. Griffith, James B. Grace, Eric M. Lind, Peter B. Adler, Lori A. Biederman, Dana M. Blumenthal, et al. “Herbivory and eutrophication mediate grassland plant nutrient responses across a global climatic gradient.” Ecology 99, no. 4 (April 2018): 822–31. https://doi.org/10.1002/ecy.2175.
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  - Frater, P. N., E. T. Borer, P. A. Fay, V. Jin, B. Knaeble, E. Seabloom, L. Sullivan, D. A. Wedin, and W. S. Harpole. “Nutrients and environment influence arbuscular mycorrhizal colonization both independently and interactively in Schizachyrium scoparium.” Plant and Soil 425, no. 1–2 (April 1, 2018): 493–506. https://doi.org/10.1007/s11104-018-3597-6.
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  - Moris, Dimitrios, Ioannis Ntanasis-Stathopoulos, Diamantis I. Tsilimigras, Mohamad A. Adam, Chi-Fu Jeffrey Yang, David Harpole, and Stamatios Theocharis. “Insights into Novel Prognostic and Possible Predictive Biomarkers of Lung Neuroendocrine Tumors.” Cancer Genomics Proteomics 15, no. 2 (March 2018): 153–63. https://doi.org/10.21873/cgp.20073.
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  - Yang, Chi-Fu Jeffrey, Frances McSherry, Nicholas R. Mayne, Xiaofei Wang, Mark F. Berry, Betty Tong, David H. Harpole, et al. “Surgical Outcomes After Neoadjuvant Chemotherapy and Ipilimumab for Non-Small Cell Lung Cancer.” Ann Thorac Surg 105, no. 3 (March 2018): 924–29. https://doi.org/10.1016/j.athoracsur.2017.09.030.
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  - Hautier, Yann, Forest Isbell, Elizabeth T. Borer, Eric W. Seabloom, W Stanley Harpole, Eric M. Lind, Andrew S. MacDougall, et al. “Local loss and spatial homogenization of plant diversity reduce ecosystem multifunctionality.” Nat Ecol Evol 2, no. 1 (January 2018): 50–56. https://doi.org/10.1038/s41559-017-0395-0.
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  - Hillebrand, H., B. Blasius, E. T. Borer, J. M. Chase, J. A. Downing, B. K. Eriksson, C. T. Filstrup, et al. “Biodiversity change is uncoupled from species richness trends: Consequences for conservation and monitoring.” Journal of Applied Ecology 55, no. 1 (January 1, 2018): 169–84. https://doi.org/10.1111/1365-2664.12959.
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  - Mortensen, B., B. Danielson, W. S. Harpole, J. Alberti, C. A. Arnillas, L. Biederman, E. T. Borer, et al. “Herbivores safeguard plant diversity by reducing variability in dominance.” Journal of Ecology 106, no. 1 (January 1, 2018): 101–12. https://doi.org/10.1111/1365-2745.12821.
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  - Yi, John S., Neal Ready, Patrick Healy, Chelsae Dumbauld, Robyn Osborne, Mark Berry, Debra Shoemaker, et al. “Immune Activation in Early-Stage Non-Small Cell Lung Cancer Patients Receiving Neoadjuvant Chemotherapy Plus Ipilimumab.” Clin Cancer Res 23, no. 24 (December 15, 2017): 7474–82. https://doi.org/10.1158/1078-0432.CCR-17-2005.
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  - Boyer, Matthew J., Christina D. Williams, David H. Harpole, Mark W. Onaitis, Michael J. Kelley, and Joseph K. Salama. “Improved Survival of Stage I Non-Small Cell Lung Cancer: A VA Central Cancer Registry Analysis.” J Thorac Oncol 12, no. 12 (December 2017): 1814–23. https://doi.org/10.1016/j.jtho.2017.09.1952.
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  - Anderson, Kevin L., Michael S. Mulvihill, Paul J. Speicher, Babatunde A. Yerokun, Brian C. Gulack, Daniel P. Nussbaum, David H. Harpole, Thomas A. D’Amico, Mark F. Berry, and Matthew G. Hartwig. “Adjuvant Chemotherapy Does Not Confer Superior Survival in Patients With Atypical Carcinoid Tumors.” Ann Thorac Surg 104, no. 4 (October 2017): 1221–30. https://doi.org/10.1016/j.athoracsur.2017.05.011.
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  - Harpole, W. S., L. L. Sullivan, E. M. Lind, J. Firn, P. B. Adler, E. T. Borer, J. Chase, et al. “Out of the shadows: multiple nutrient limitations drive relationships among biomass, light and plant diversity.” Functional Ecology 31, no. 9 (September 1, 2017): 1839–46. https://doi.org/10.1111/1365-2435.12967.
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  - Yao, Xiaoxin I., Xiaofei Wang, Paul J. Speicher, E Shelley Hwang, Perry Cheng, David H. Harpole, Mark F. Berry, Deborah Schrag, and Herbert H. Pang. “Reporting and Guidelines in Propensity Score Analysis: A Systematic Review of Cancer and Cancer Surgical Studies.” J Natl Cancer Inst 109, no. 8 (August 1, 2017). https://doi.org/10.1093/jnci/djw323.
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  - Yerokun, Babatunde A., Chi-Fu Jeffrey Yang, Brian C. Gulack, Xuechan Li, Michael S. Mulvihill, Lin Gu, Xiaofei Wang, et al. “A national analysis of wedge resection versus stereotactic body radiation therapy for stage IA non-small cell lung cancer.” J Thorac Cardiovasc Surg 154, no. 2 (August 2017): 675-686.e4. https://doi.org/10.1016/j.jtcvs.2017.02.065.
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  - Yang, Chi-Fu Jeffrey, Derek Y. Chan, Paul J. Speicher, Brian C. Gulack, Betty C. Tong, Matthew G. Hartwig, Christopher R. Kelsey, Thomas A. D’Amico, Mark F. Berry, and David H. Harpole. “Surgery Versus Optimal Medical Management for N1 Small Cell Lung Cancer.” Ann Thorac Surg 103, no. 6 (June 2017): 1767–72. https://doi.org/10.1016/j.athoracsur.2017.01.043.
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  - “Discussion.” J Thorac Cardiovasc Surg 153, no. 6 (June 2017): 1576–78. https://doi.org/10.1016/j.jtcvs.2016.12.065.
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  - Borer, Elizabeth T., James B. Grace, W Stanley Harpole, Andrew S. MacDougall, and Eric W. Seabloom. “A decade of insights into grassland ecosystem responses to global environmental change.” Nat Ecol Evol 1, no. 5 (April 20, 2017): 118. https://doi.org/10.1038/s41559-017-0118.
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  - Cox, Morgan L., Chi-Fu Jeffrey Yang, Paul J. Speicher, Kevin L. Anderson, Zachary W. Fitch, Lin Gu, Robert Patrick Davis, et al. “The Role of Extent of Surgical Resection and Lymph Node Assessment for Clinical Stage I Pulmonary Lepidic Adenocarcinoma: An Analysis of 1991 Patients.” J Thorac Oncol 12, no. 4 (April 2017): 689–96. https://doi.org/10.1016/j.jtho.2017.01.003.
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  - Yang, Chi-Fu Jeffrey, Derek Y. Chan, Thomas A. D’Amico, Mark F. Berry, and David H. Harpole. “Reply to D.A. Palma.” J Clin Oncol 35, no. 5 (February 10, 2017): 572. https://doi.org/10.1200/JCO.2016.70.2787.
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  - Giattino, Charles M., Jacob E. Gardner, Faris M. Sbahi, Kenneth C. Roberts, Mary Cooter, Eugene Moretti, Jeffrey N. Browndyke, et al. “Intraoperative Frontal Alpha-Band Power Correlates with Preoperative Neurocognitive Function in Older Adults.” Front Syst Neurosci 11 (2017): 24. https://doi.org/10.3389/fnsys.2017.00024.
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  - Torok, Jordan A., Lin Gu, Daniel J. Tandberg, Xiaofei Wang, David H. Harpole, Chris R. Kelsey, and Joseph K. Salama. “Patterns of Distant Metastases After Surgical Management of Non-Small-cell Lung Cancer.” Clin Lung Cancer 18, no. 1 (January 2017): e57–70. https://doi.org/10.1016/j.cllc.2016.06.011.
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  - Yang, Chi-Fu Jeffrey, Derek Y. Chan, Xiaofei Wang, Thomas A. D’Amico, David H. Harpole, and Mark F. Berry. “Reply to T.-H. Wang et al.” J Clin Oncol 35, no. 1 (January 2017): 118–20. https://doi.org/10.1200/JCO.2016.68.6980.
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  - Gulack, Brian C., Chi-Fu Jeffrey Yang, Paul J. Speicher, Babatunde A. Yerokun, Betty C. Tong, Mark W. Onaitis, Thomas A. D’Amico, David H. Harpole, Matthew G. Hartwig, and Mark F. Berry. “A Risk Score to Assist Selecting Lobectomy Versus Sublobar Resection for Early Stage Non-Small Cell Lung Cancer.” Ann Thorac Surg 102, no. 6 (December 2016): 1814–20. https://doi.org/10.1016/j.athoracsur.2016.06.032.
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  - Speicher, Paul J., Zachary W. Fitch, Brian C. Gulack, Chi-Fu J. Yang, Betty C. Tong, David H. Harpole, Thomas A. D’Amico, Mark F. Berry, and Matthew G. Hartwig. “Induction Chemotherapy is Not Superior to a Surgery-First Strategy for Clinical N1 Non-Small Cell Lung Cancer.” Ann Thorac Surg 102, no. 3 (September 2016): 884–94. https://doi.org/10.1016/j.athoracsur.2016.05.065.
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  - Yang, Chi-Fu Jeffrey, Brandon W. Yan, Robert Ryan Meyerhoff, Shakir M. Saud, Brian C. Gulack, Paul J. Speicher, Matthew G. Hartwig, Thomas A. D’Amico, David H. Harpole, and Mark F. Berry. “Impact of Age on Long-Term Outcomes of Surgery for Malignant Pleural Mesothelioma.” Clin Lung Cancer 17, no. 5 (September 2016): 419–26. https://doi.org/10.1016/j.cllc.2016.03.002.
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  - Yang, Chi-Fu Jeffrey, Nicholas R. Mayne, Hanghang Wang, Ryan R. Meyerhoff, Sameer Hirji, Betty C. Tong, Matthew Hartwig, David Harpole, Thomas A. D’Amico, and Mark Berry. “Outcomes of Major Lung Resection After Induction Therapy for Non-Small Cell Lung Cancer in Elderly Patients.” Ann Thorac Surg 102, no. 3 (September 2016): 962–70. https://doi.org/10.1016/j.athoracsur.2016.03.088.
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  - Yerokun, Babatunde A., Zhifei Sun, Chi-Fu Jeffrey Yang, Brian C. Gulack, Paul J. Speicher, Mohamed A. Adam, Thomas A. D’Amico, et al. “Minimally Invasive Versus Open Esophagectomy for Esophageal Cancer: A Population-Based Analysis.” Ann Thorac Surg 102, no. 2 (August 2016): 416–23. https://doi.org/10.1016/j.athoracsur.2016.02.078.
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  - Yang, Chi-Fu Jeffrey, Robert Ryan Meyerhoff, Nicholas Ryan Mayne, Terry Singhapricha, Christopher B. Toomey, Paul J. Speicher, Matthew G. Hartwig, et al. “Long-term survival following open versus thoracoscopic lobectomy after preoperative chemotherapy for non-small cell lung cancer.” Eur J Cardiothorac Surg 49, no. 6 (June 2016): 1615–23. https://doi.org/10.1093/ejcts/ezv428.
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  - Yang, Chi-Fu Jeffrey, Syed M. Adil, Kevin L. Anderson, Robert Ryan Meyerhoff, Ryan S. Turley, Matthew G. Hartwig, David H. Harpole, et al. “Impact of patient selection and treatment strategies on outcomes after lobectomy for biopsy-proven stage IIIA pN2 non-small cell lung cancer.” Eur J Cardiothorac Surg 49, no. 6 (June 2016): 1607–13. https://doi.org/10.1093/ejcts/ezv431.
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  - Yang, Chi-Fu Jeffrey, Derek Y. Chan, Paul J. Speicher, Brian C. Gulack, Xiaofei Wang, Matthew G. Hartwig, Mark W. Onaitis, et al. “Role of Adjuvant Therapy in a Population-Based Cohort of Patients With Early-Stage Small-Cell Lung Cancer.” J Clin Oncol 34, no. 10 (April 1, 2016): 1057–64. https://doi.org/10.1200/JCO.2015.63.8171.
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  - Yang, Chi-Fu Jeffrey, Zhifei Sun, Paul J. Speicher, Shakir M. Saud, Brian C. Gulack, Matthew G. Hartwig, David H. Harpole, et al. “Use and Outcomes of Minimally Invasive Lobectomy for Stage I Non-Small Cell Lung Cancer in the National Cancer Data Base.” Ann Thorac Surg 101, no. 3 (March 2016): 1037–42. https://doi.org/10.1016/j.athoracsur.2015.11.018.
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  - Scott, Christopher D., and David H. Harpole. “The Biology of Pulmonary Metastasis.” Thorac Surg Clin 26, no. 1 (February 2016): 1–6. https://doi.org/10.1016/j.thorsurg.2015.09.001.
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  - Harpole, David H. “The Integrated Comprehensive Care Program: A Novel Home Care Initiative After Major Thoracic Surgery.” Semin Thorac Cardiovasc Surg 28, no. 2 (2016): 582–84. https://doi.org/10.1053/j.semtcvs.2016.05.005.
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  - Yang, Chi-Fu Jeffrey, Brian C. Gulack, Lin Gu, Paul J. Speicher, Xiaofei Wang, David H. Harpole, Mark W. Onaitis, Thomas A. D’Amico, Mark F. Berry, and Matthew G. Hartwig. “Adding radiation to induction chemotherapy does not improve survival of patients with operable clinical N2 non-small cell lung cancer.” J Thorac Cardiovasc Surg 150, no. 6 (December 2015): 1484–92. https://doi.org/10.1016/j.jtcvs.2015.06.062.
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  - Saunders, Laura R., Alexander J. Bankovich, Wade C. Anderson, Monette A. Aujay, Sheila Bheddah, KristenAnn Black, Radhika Desai, et al. “A DLL3-targeted antibody-drug conjugate eradicates high-grade pulmonary neuroendocrine tumor-initiating cells in vivo.” Sci Transl Med 7, no. 302 (August 26, 2015): 302ra136. https://doi.org/10.1126/scitranslmed.aac9459.
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  - Berry, Mark F., Chi-Fu Jeffrey Yang, Matthew G. Hartwig, Betty C. Tong, David H. Harpole, Thomas A. D’Amico, and Mark W. Onaitis. “Impact of Pulmonary Function Measurements on Long-Term Survival After Lobectomy for Stage I Non-Small Cell Lung Cancer.” Ann Thorac Surg 100, no. 1 (July 2015): 271–76. https://doi.org/10.1016/j.athoracsur.2015.02.076.
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  - Yang, Chi-Fu Jeffrey, R Ryan Meyerhoff, Sarah J. Stephens, Terry Singhapricha, Christopher B. Toomey, Kevin L. Anderson, Chris Kelsey, David Harpole, Thomas A. D’Amico, and Mark F. Berry. “Long-Term Outcomes of Lobectomy for Non-Small Cell Lung Cancer After Definitive Radiation Treatment.” Ann Thorac Surg 99, no. 6 (June 2015): 1914–20. https://doi.org/10.1016/j.athoracsur.2015.01.064.
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  - Little, Alex G., Antoon E. Lerut, David H. Harpole, Wayne L. Hofstetter, John D. Mitchell, Nasser K. Altorki, and Mark J. Krasna. “The Society of Thoracic Surgeons practice guidelines on the role of multimodality treatment for cancer of the esophagus and gastroesophageal junction.” Ann Thorac Surg 98, no. 5 (November 2014): 1880–85. https://doi.org/10.1016/j.athoracsur.2014.07.069.
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  - Malik, Shakun M., Richard Pazdur, Jeffrey S. Abrams, Mark A. Socinski, William T. Sause, David H. Harpole, John J. Welch, Edward L. Korn, Claudio Dansky Ullmann, and Fred R. Hirsch. “Consensus report of a joint NCI thoracic malignancies steering committee: FDA workshop on strategies for integrating biomarkers into clinical development of new therapies for lung cancer leading to the inception of "master protocols" in lung cancer.” J Thorac Oncol 9, no. 10 (October 2014): 1443–48. https://doi.org/10.1097/JTO.0000000000000314.
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  - Harpole, W. S., and L. A. Biederman. “On the importance of accurate reporting: A response to comments on 'Biochar and its effects on plant productivity and nutrient cycling: A meta-analysis'.” Gcb Bioenergy 6, no. 3 (January 1, 2014): 172–75. https://doi.org/10.1111/gcbb.12093.
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  - Jaklitsch, Michael T., Lin Gu, Todd Demmy, David H. Harpole, Thomas A. D’Amico, Robert J. McKenna, Mark J. Krasna, et al. “Prospective phase II trial of preresection thoracoscopic mediastinal restaging after neoadjuvant therapy for IIIA (N2) non-small cell lung cancer: results of CALGB Protocol 39803.” J Thorac Cardiovasc Surg 146, no. 1 (July 2013): 9–16. https://doi.org/10.1016/j.jtcvs.2012.12.069.
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  - Erhunmwunsee, Loretta, Mary-Beth M. Joshi, Debbi H. Conlon, and David H. Harpole. “Neighborhood-level socioeconomic determinants impact outcomes in nonsmall cell lung cancer patients in the Southeastern United States.” Cancer 118, no. 20 (October 15, 2012): 5117–23. https://doi.org/10.1002/cncr.26185.
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  - Cuneo, Kyle C., Richard F. Riedel, Leslie G. Dodd, David H. Harpole, and David G. Kirsch. “Pathologic complete response of a malignant peripheral nerve sheath tumor in the lung treated with neoadjuvant Ifosfamide and radiation therapy.” J Clin Oncol 30, no. 28 (October 1, 2012): e291–93. https://doi.org/10.1200/JCO.2012.42.8797.
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  - Ceppa, DuyKhanh P., Andrzej S. Kosinski, Mark F. Berry, Betty C. Tong, David H. Harpole, John D. Mitchell, Thomas A. D’Amico, and Mark W. Onaitis. “Thoracoscopic lobectomy has increasing benefit in patients with poor pulmonary function: a Society of Thoracic Surgeons Database analysis.” Ann Surg 256, no. 3 (September 2012): 487–93. https://doi.org/10.1097/SLA.0b013e318265819c.
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  - Patel, Pretesh R., Sua Yoo, Gloria Broadwater, Lawrence B. Marks, Edward F. Miles, Thomas A. D’Amico, David Harpole, and Chris R. Kelsey. “Effect of increasing experience on dosimetric and clinical outcomes in the management of malignant pleural mesothelioma with intensity-modulated radiation therapy.” Int J Radiat Oncol Biol Phys 83, no. 1 (May 1, 2012): 362–68. https://doi.org/10.1016/j.ijrobp.2011.11.057.
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  - Berry, Mark F., Mark W. Onaitis, Betty C. Tong, Stafford S. Balderson, David H. Harpole, and Thomas A. D’Amico. “Feasibility of hybrid thoracoscopic lobectomy and en-bloc chest wall resection.” Eur J Cardiothorac Surg 41, no. 4 (April 2012): 888–92. https://doi.org/10.1093/ejcts/ezr150.
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  - Shah, Asad A., Michael E. Barfield, Chris R. Kelsey, Mark W. Onaitis, Betty Tong, David Harpole, Thomas A. D’Amico, and Mark F. Berry. “Outcomes after surgical management of synchronous bilateral primary lung cancers.” Ann Thorac Surg 93, no. 4 (April 2012): 1055–60. https://doi.org/10.1016/j.athoracsur.2011.12.070.
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  - Tong, Betty C., and David H. Harpole. “Molecular markers for incidence, prognosis, and response to therapy.” Surg Oncol Clin N Am 21, no. 1 (January 2012): 161–75. https://doi.org/10.1016/j.soc.2011.09.007.
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  - Ceppa, Duykhanh P., Ian J. Welsby, Tracy Y. Wang, Mark W. Onaitis, Betty C. Tong, David H. Harpole, Thomas A. D’Amico, and Mark F. Berry. “Perioperative management of patients on clopidogrel (Plavix) undergoing major lung resection.” Ann Thorac Surg 92, no. 6 (December 2011): 1971–76. https://doi.org/10.1016/j.athoracsur.2011.07.052.
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  - D’Alonzo, Richard C., Elliott Bennett-Guerrero, Mihai Podgoreanu, Thomas A. D’Amico, David H. Harpole, and Andrew D. Shaw. “A randomized, double blind, placebo controlled clinical trial of the preoperative use of ketamine for reducing inflammation and pain after thoracic surgery.” J Anesth 25, no. 5 (October 2011): 672–78. https://doi.org/10.1007/s00540-011-1206-4.
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  - Berry, Mark F., Mark W. Onaitis, Betty C. Tong, David H. Harpole, and Thomas A. D’Amico. “A model for morbidity after lung resection in octogenarians.” Eur J Cardiothorac Surg 39, no. 6 (June 2011): 989–94. https://doi.org/10.1016/j.ejcts.2010.09.038.
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  - Harpole, W Stanley, and Katharine N. Suding. “A test of the niche dimension hypothesis in an arid annual grassland.” Oecologia 166, no. 1 (May 2011): 197–205. https://doi.org/10.1007/s00442-010-1808-9.
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  - Onaitis, Mark, Thomas A. D’Amico, Cheryl P. Clark, Justin Guinney, David H. Harpole, and Emma L. Rawlins. “A 10-gene progenitor cell signature predicts poor prognosis in lung adenocarcinoma.” Ann Thorac Surg 91, no. 4 (April 2011): 1046–50. https://doi.org/10.1016/j.athoracsur.2010.12.054.
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  - Berry, Mark F., B Zane Atkins, Betty C. Tong, David H. Harpole, Thomas A. D’Amico, and Mark W. Onaitis. “A comprehensive evaluation for aspiration after esophagectomy reduces the incidence of postoperative pneumonia.” J Thorac Cardiovasc Surg 140, no. 6 (December 2010): 1266–71. https://doi.org/10.1016/j.jtcvs.2010.08.038.
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  - Cadotte, M. W., E. T. Borer, E. W. Seabloom, J. Cavender-Bares, W. S. Harpole, E. Cleland, and K. F. Davies. “Phylogenetic patterns differ for native and exotic plant communities across a richness gradient in Northern California.” Diversity and Distributions 16, no. 6 (November 1, 2010): 892–901. https://doi.org/10.1111/j.1472-4642.2010.00700.x.
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  - Onaitis, Mark, Thomas D’Amico, Yue Zhao, Sean O’Brien, and David Harpole. “Risk factors for atrial fibrillation after lung cancer surgery: analysis of the Society of Thoracic Surgeons general thoracic surgery database.” Ann Thorac Surg 90, no. 2 (August 2010): 368–74. https://doi.org/10.1016/j.athoracsur.2010.03.100.
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  - Berry, Mark F., Nestor R. Villamizar-Ortiz, Betty C. Tong, William R. Burfeind, David H. Harpole, Thomas A. D’Amico, and Mark W. Onaitis. “Pulmonary function tests do not predict pulmonary complications after thoracoscopic lobectomy.” Ann Thorac Surg 89, no. 4 (April 2010): 1044–51. https://doi.org/10.1016/j.athoracsur.2009.12.065.
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  - Burfeind, William R., Nikhil P. Jaik, Nestor Villamizar, Eric M. Toloza, David H. Harpole, and Thomas A. D’Amico. “A cost-minimisation analysis of lobectomy: thoracoscopic versus posterolateral thoracotomy.” Eur J Cardiothorac Surg 37, no. 4 (April 2010): 827–32. https://doi.org/10.1016/j.ejcts.2009.10.017.
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  - Paul, Subroto, Nasser K. Altorki, Shubin Sheng, Paul C. Lee, David H. Harpole, Mark W. Onaitis, Brendon M. Stiles, Jeffrey L. Port, and Thomas A. D’Amico. “Thoracoscopic lobectomy is associated with lower morbidity than open lobectomy: a propensity-matched analysis from the STS database.” J Thorac Cardiovasc Surg 139, no. 2 (February 2010): 366–78. https://doi.org/10.1016/j.jtcvs.2009.08.026.
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  - Tong, Betty C., Jennifer Hanna, Eric M. Toloza, Mark W. Onaitis, Thomas A. D’Amico, David H. Harpole, and William R. Burfeind. “Outcomes of video-assisted thoracoscopic decortication.” Ann Thorac Surg 89, no. 1 (January 2010): 220–25. https://doi.org/10.1016/j.athoracsur.2009.09.021.
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  - Berry, Mark F., Jennifer Hanna, Betty C. Tong, William R. Burfeind, David H. Harpole, Thomas A. D’Amico, and Mark W. Onaitis. “Risk factors for morbidity after lobectomy for lung cancer in elderly patients.” Ann Thorac Surg 88, no. 4 (October 2009): 1093–99. https://doi.org/10.1016/j.athoracsur.2009.06.012.
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  - West, Howard, David Harpole, and William Travis. “Histologic considerations for individualized systemic therapy approaches for the management of non-small cell lung cancer.” Chest 136, no. 4 (October 2009): 1112–18. https://doi.org/10.1378/chest.08-2484.
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  - West, Howard, Rogerio Lilenbaum, David Harpole, Antoinette Wozniak, and Lecia Sequist. “Molecular analysis-based treatment strategies for the management of non-small cell lung cancer.” J Thorac Oncol 4, no. 9 Suppl 2 (September 2009): S1029–39. https://doi.org/10.1097/JTO.0b013e3181b27170.
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  - Villamizar, Nestor R., Marcus D. Darrabie, William R. Burfeind, Rebecca P. Petersen, Mark W. Onaitis, Eric Toloza, David H. Harpole, and Thomas A. D’Amico. “Thoracoscopic lobectomy is associated with lower morbidity compared with thoracotomy.” J Thorac Cardiovasc Surg 138, no. 2 (August 2009): 419–25. https://doi.org/10.1016/j.jtcvs.2009.04.026.
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  - Onaitis, Mark W., Rebecca P. Petersen, John C. Haney, Leonard Saltz, Bernard Park, Raja Flores, Nabil Rizk, et al. “Prognostic factors for recurrence after pulmonary resection of colorectal cancer metastases.” Ann Thorac Surg 87, no. 6 (June 2009): 1684–88. https://doi.org/10.1016/j.athoracsur.2009.03.034.
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  - Joshi, M. M., B. Seligmann, C. Sabalos, and D. H. Harpole. “Measurement of gene expression biomarkers by qNPA from archived NSCLC FFPE: Prognosis of 5-year survival.” J Clin Oncol 27, no. 15_suppl (May 20, 2009): 11098.
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  - Jones, Lee W., Neil D. Eves, Bercedis L. Peterson, Jennifer Garst, Jeffrey Crawford, Miranda J. West, Stephanie Mabe, David Harpole, William E. Kraus, and Pamela S. Douglas. “Safety and feasibility of aerobic training on cardiopulmonary function and quality of life in postsurgical nonsmall cell lung cancer patients: a pilot study.” Cancer 113, no. 12 (December 15, 2008): 3430–39. https://doi.org/10.1002/cncr.23967.
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  - Strauss, Gary M., James E. Herndon, Michael A. Maddaus, David W. Johnstone, Elizabeth A. Johnson, David H. Harpole, Heidi H. Gillenwater, et al. “Adjuvant paclitaxel plus carboplatin compared with observation in stage IB non-small-cell lung cancer: CALGB 9633 with the Cancer and Leukemia Group B, Radiation Therapy Oncology Group, and North Central Cancer Treatment Group Study Groups.” J Clin Oncol 26, no. 31 (November 1, 2008): 5043–51. https://doi.org/10.1200/JCO.2008.16.4855.
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  - Burfeind, William R., Betty C. Tong, Erin O’Branski, James E. Herndon, Eric M. Toloza, Thomas A. D’Amico, Linda H. Harpole, and David H. Harpole. “Quality of life outcomes are equivalent after lobectomy in the elderly.” J Thorac Cardiovasc Surg 136, no. 3 (September 2008): 597–604. https://doi.org/10.1016/j.jtcvs.2008.02.093.
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  - Kelsey, C. R., J. A. Boyd, J. L. Hubbs, D. R. Hollis, J. Crawford, N. E. Ready, T. A. D’Amcio, D. H. Harpole, J. Garst, and L. B. Marks. “Local/regional recurrence following surgery for early-stage lung cancer: A 10-year experience with 975 patients.” J Clin Oncol 26, no. 15_suppl (May 20, 2008): 7542.
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  - Atkins, B Zane, David H. Harpole, Jennifer H. Mangum, Eric M. Toloza, Thomas A. D’Amico, and William R. Burfeind. “Pulmonary segmentectomy by thoracotomy or thoracoscopy: reduced hospital length of stay with a minimally-invasive approach.” Ann Thorac Surg 84, no. 4 (October 2007): 1107–12. https://doi.org/10.1016/j.athoracsur.2007.05.013.
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  - Hsu, David S., Bala S. Balakumaran, Chaitanya R. Acharya, Vanja Vlahovic, Kelli S. Walters, Katherine Garman, Carey Anders, et al. “Pharmacogenomic strategies provide a rational approach to the treatment of cisplatin-resistant patients with advanced cancer.” J Clin Oncol 25, no. 28 (October 1, 2007): 4350–57. https://doi.org/10.1200/JCO.2007.11.0593.
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  - Tong, Betty C., and David H. Harpole. “Audit, quality control, and performance in thoracic surgery: a North American perspective.” Thorac Surg Clin 17, no. 3 (August 2007): 379–86. https://doi.org/10.1016/j.thorsurg.2007.08.003.
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  - Loewen, Gregory M., Dorothy Watson, Leslie Kohman, James E. Herndon, Hani Shennib, Kemp Kernstine, Jemi Olak, et al. “Preoperative exercise Vo2 measurement for lung resection candidates: results of Cancer and Leukemia Group B Protocol 9238.” J Thorac Oncol 2, no. 7 (July 2007): 619–25. https://doi.org/10.1097/JTO.0b013e318074bba7.
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  - Harpole, David H. “Prognostic modeling in early stage lung cancer: an evolving process from histopathology to genomics.” Thorac Surg Clin 17, no. 2 (May 2007): 167–viii. https://doi.org/10.1016/j.thorsurg.2007.03.014.
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  - Petersen, Rebecca P., DuyKhanh Pham, William R. Burfeind, Steven I. Hanish, Eric M. Toloza, David H. Harpole, and Thomas A. D’Amico. “Thoracoscopic lobectomy facilitates the delivery of chemotherapy after resection for lung cancer.” Ann Thorac Surg 83, no. 4 (April 2007): 1245–49. https://doi.org/10.1016/j.athoracsur.2006.12.029.
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  - Czito, Brian G., Chris R. Kelsey, Herbert I. Hurwitz, Chris G. Willett, Michael A. Morse, Gerard C. Blobe, Nishan H. Fernando, et al. “A Phase I study of capecitabine, carboplatin, and paclitaxel with external beam radiation therapy for esophageal carcinoma.” Int J Radiat Oncol Biol Phys 67, no. 4 (March 15, 2007): 1002–7. https://doi.org/10.1016/j.ijrobp.2006.10.027.
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  - Petersen, Rebecca P., Steven I. Hanish, John C. Haney, Charles C. Miller, William R. Burfeind, Douglas S. Tyler, Hilliard F. Seigler, Walter Wolfe, Thomas A. D’Amico, and David H. Harpole. “Improved survival with pulmonary metastasectomy: an analysis of 1720 patients with pulmonary metastatic melanoma.” J Thorac Cardiovasc Surg 133, no. 1 (January 2007): 104–10. https://doi.org/10.1016/j.jtcvs.2006.08.065.
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  - Petersen, Rebecca P., Michael J. Campa, Justin Sperlazza, Debbi Conlon, Mary-Beth Joshi, David H. Harpole, and Edward F. Patz. “Tumor infiltrating Foxp3+ regulatory T-cells are associated with recurrence in pathologic stage I NSCLC patients.” Cancer 107, no. 12 (December 15, 2006): 2866–72. https://doi.org/10.1002/cncr.22282.
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  - Harpole, David H., and Shari L. Meyerson. “Lung cancer staging: proteomics.” Thorac Surg Clin 16, no. 4 (November 2006): 339–43. https://doi.org/10.1016/j.thorsurg.2006.10.001.
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  - Lemaire, Anthony, Ivana Nikolic, Thomas Petersen, Jack C. Haney, Eric M. Toloza, David H. Harpole, Thomas A. D’Amico, and William R. Burfeind. “Nine-year single center experience with cervical mediastinoscopy: complications and false negative rate.” Ann Thorac Surg 82, no. 4 (October 2006): 1185–89. https://doi.org/10.1016/j.athoracsur.2006.05.023.
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  - Posther, Katherine E., Linda M. McCall, David H. Harpole, Carolyn E. Reed, Joe B. Putnam, Valerie W. Rusch, and Barry A. Siegel. “Yield of brain 18F-FDG PET in evaluating patients with potentially operable non-small cell lung cancer.” J Nucl Med 47, no. 10 (October 2006): 1607–11.
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  - Onaitis, Mark W., Rebecca P. Petersen, Stafford S. Balderson, Eric Toloza, William R. Burfeind, David H. Harpole, and Thomas A. D’Amico. “Thoracoscopic lobectomy is a safe and versatile procedure: experience with 500 consecutive patients.” Ann Surg 244, no. 3 (September 2006): 420–25. https://doi.org/10.1097/01.sla.0000234892.79056.63.
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  - Potti, Anil, Sayan Mukherjee, Rebecca Petersen, Holly K. Dressman, Andrea Bild, Jason Koontz, Robert Kratzke, et al. “A genomic strategy to refine prognosis in early-stage non-small-cell lung cancer.” N Engl J Med 355, no. 6 (August 10, 2006): 570–80. https://doi.org/10.1056/NEJMoa060467.
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  - Dressman, Holly K., Andrea Bild, Jennifer Garst, David Harpole, and Anil Potti. “Genomic signatures in non-small-cell lung cancer: targeting the targeted therapies.” Curr Oncol Rep 8, no. 4 (July 2006): 252–57. https://doi.org/10.1007/s11912-006-0029-1.
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  - Petersen, Rebecca P., Duykhanh Pham, Eric M. Toloza, William R. Burfeind, David H. Harpole, Steven I. Hanish, and Thomas A. D’Amico. “Thoracoscopic lobectomy: a safe and effective strategy for patients receiving induction therapy for non-small cell lung cancer.” Ann Thorac Surg 82, no. 1 (July 2006): 214–18. https://doi.org/10.1016/j.athoracsur.2006.02.051.
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  - Petersen, Rebecca P., and David H. Harpole. “Computed tomography screening for the early detection of lung cancer.” J Natl Compr Canc Netw 4, no. 6 (July 2006): 591–94. https://doi.org/10.6004/jnccn.2006.0048.
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  - Harpole, D. H., M. M. Joshi, R. P. Petersen, D. H. Conlon, K. Tanaka, D. Shimizu, H. Kuramochi, M. Williams, P. V. Danenberg, and K. Danenberg. “A lung cancer genomic risk prediction model derived from paraffin-embedded tissue.” J Clin Oncol 24, no. 18_suppl (June 20, 2006): 10059.
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  - Harpole, D. H., R. Petersen, S. Mukherjee, A. Bild, H. Dressman, R. Kratzke, M. J. Kelley, et al. “A genomic strategy to refine prognosis in early stage non-small cell lung carcinoma (NSCLC).” J Clin Oncol 24, no. 18_suppl (June 20, 2006): 7026.
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  - Joshi, M. M., R. P. Petersen, D. H. Conlon, K. Tanaka, D. Shimizu, H. Kuramochi, M. Williams, P. V. Danenberg, K. D. Danenberg, and D. H. Harpole. “Differential canonical pathways derived from microarrays using RNA from paraffin-embedded non-small cell lung cancer tissue.” J Clin Oncol 24, no. 18_suppl (June 20, 2006): 7226.
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  - D’Amico, Thomas A., Kelli R. Brooks, Mary-Beth Moore Joshi, Debbi Conlon, James Herndon, Rebecca P. Petersen, and David H. Harpole. “Serum protein expression predicts recurrence in patients with early-stage lung cancer after resection.” Ann Thorac Surg 81, no. 6 (June 2006): 1982–87. https://doi.org/10.1016/j.athoracsur.2006.01.042.
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  - Allen, Mark S., Gail E. Darling, Taine T. V. Pechet, John D. Mitchell, James E. Herndon, Rodney J. Landreneau, Richard I. Inculet, et al. “Morbidity and mortality of major pulmonary resections in patients with early-stage lung cancer: initial results of the randomized, prospective ACOSOG Z0030 trial.” Ann Thorac Surg 81, no. 3 (March 2006): 1013–19. https://doi.org/10.1016/j.athoracsur.2005.06.066.
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  - Gaca, Jeffrey G., Rebecca P. Petersen, Bercedis L. Peterson, David H. Harpole, Thomas A. D’Amico, Theodore N. Pappas, Hilliard F. Seigler, Walter G. Wolfe, and Douglas S. Tyler. “Pathologic nodal status predicts disease-free survival after neoadjuvant chemoradiation for gastroesophageal junction carcinoma.” Ann Surg Oncol 13, no. 3 (March 2006): 340–46. https://doi.org/10.1245/ASO.2006.02.023.
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  - Posther, Katherine E., and David H. Harpole. “The surgical management of lung cancer.” Cancer Invest 24, no. 1 (February 2006): 56–67. https://doi.org/10.1080/07357900500449611.
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  - Bild, Andrea H., Guang Yao, Jeffrey T. Chang, Quanli Wang, Anil Potti, Dawn Chasse, Mary-Beth Joshi, et al. “Oncogenic pathway signatures in human cancers as a guide to targeted therapies.” Nature 439, no. 7074 (January 19, 2006): 353–57. https://doi.org/10.1038/nature04296.
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  - Burfeind, William R., Thomas A. D’Amico, Eric M. Toloza, Walter G. Wolfe, and David H. Harpole. “Low morbidity and mortality for bronchoplastic procedures with and without induction therapy.” Ann Thorac Surg 80, no. 2 (August 2005): 418–21. https://doi.org/10.1016/j.athoracsur.2005.02.058.
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  - Lemaire, Anthony, William R. Burfeind, Eric Toloza, Scott Balderson, Rebecca P. Petersen, David H. Harpole, and Thomas A. D’Amico. “Outcomes of tracheobronchial stents in patients with malignant airway disease.” Ann Thorac Surg 80, no. 2 (August 2005): 434–37. https://doi.org/10.1016/j.athoracsur.2005.02.071.
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  - Petersen, R. P., A. Bild, H. Dressman, M. M. Joshi, D. H. Conlon, M. West, J. R. Nevins, and D. H. Harpole. “Gene expression signatures for prognosis in NSCLC, coupled with signatures of oncogenic pathway deregulation, provide a novel approach for selection of molecular targets.” J Clin Oncol 23, no. 16_suppl (June 2005): 7020.
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  - D’Cunha, Jonathan, James E. Herndon, Debra L. Herzan, G Alexander Patterson, Leslie J. Kohman, David H. Harpole, Kemp H. Kernstine, et al. “Poor correspondence between clinical and pathologic staging in stage 1 non-small cell lung cancer: results from CALGB 9761, a prospective trial.” Lung Cancer 48, no. 2 (May 2005): 241–46. https://doi.org/10.1016/j.lungcan.2004.11.006.
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  - Joshi, Mary-Beth Moore, Yoshinori Shirota, Kathleen D. Danenberg, Debbi H. Conlon, Dennis S. Salonga, James E. Herndon, Peter V. Danenberg, and David H. Harpole. “High gene expression of TS1, GSTP1, and ERCC1 are risk factors for survival in patients treated with trimodality therapy for esophageal cancer.” Clin Cancer Res 11, no. 6 (March 15, 2005): 2215–21. https://doi.org/10.1158/1078-0432.CCR-04-1387.
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  - Burfeind, William R., and David H. Harpole. “Surgical strategies and outcomes after induction therapy for non-small cell lung cancer.” Semin Thorac Cardiovasc Surg 17, no. 3 (2005): 186–90. https://doi.org/10.1053/j.semtcvs.2005.06.015.
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  - Atkins, B Zane, Ashish S. Shah, Kelley A. Hutcheson, Jennifer H. Mangum, Theodore N. Pappas, David H. Harpole, and Thomas A. D’Amico. “Reducing hospital morbidity and mortality following esophagectomy.” Ann Thorac Surg 78, no. 4 (October 2004): 1170–76. https://doi.org/10.1016/j.athoracsur.2004.02.034.
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  - Allen, Mark S., Douglas E. Wood, Ronald W. Hawkinson, David H. Harpole, Robert J. McKenna, Garrett L. Walsh, Eric Vallieres, et al. “Prospective randomized study evaluating a biodegradable polymeric sealant for sealing intraoperative air leaks that occur during pulmonary resection.” Ann Thorac Surg 77, no. 5 (May 2004): 1792–1801. https://doi.org/10.1016/j.athoracsur.2003.10.049.
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  - McKenna, Robert J., Joshua O. Benditt, Malcolm DeCamp, Claude Deschamps, Larry Kaiser, Shing M. Lee, Zab Mohsenifar, et al. “Safety and efficacy of median sternotomy versus video-assisted thoracic surgery for lung volume reduction surgery.” J Thorac Cardiovasc Surg 127, no. 5 (May 2004): 1350–60. https://doi.org/10.1016/j.jtcvs.2003.11.025.
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  - Rizzo, Marco, S Scott Balderson, David H. Harpole, and L Scott Levin. “Thoracoscopic sympathectomy in the management of vasomotor disturbances and complex regional pain syndrome of the hand.” Orthopedics 27, no. 1 (January 2004): 49–52.
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  - Reed, Carolyn E., David H. Harpole, Katherine E. Posther, Sandra L. Woolson, Robert J. Downey, Bryan F. Meyers, Robert T. Heelan, et al. “Results of the American College of Surgeons Oncology Group Z0050 trial: the utility of positron emission tomography in staging potentially operable non-small cell lung cancer.” J Thorac Cardiovasc Surg 126, no. 6 (December 2003): 1943–51. https://doi.org/10.1016/j.jtcvs.2003.07.030.
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  - Ghanayem, N. S., G. M. Hoffman, K. A. Mussatto, J. R. Cava, P. C. Frommelt, N. A. Rudd, M. M. Steltzer, et al. “Home surveillance program prevents interstage mortality after the Norwood procedure.” J Thorac Cardiovasc Surg 126, no. 5 (November 2003): 1367–77. https://doi.org/10.1016/s0022-5223(03)00071-0.
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  - Brooks, Kelli R., Kathleen To, Mary-Beth Moore Joshi, Debbi H. Conlon, James E. Herndon, Thomas A. D’Amico, and David H. Harpole. “Measurement of chemoresistance markers in patients with stage III non-small cell lung cancer: a novel approach for patient selection.” Ann Thorac Surg 76, no. 1 (July 2003): 187–93. https://doi.org/10.1016/s0003-4975(03)00131-0.
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  - Rentz, Jeffrey, David Bull, David Harpole, Stephen Bailey, Leigh Neumayer, Theodore Pappas, Barbara Krasnicka, William Henderson, Jennifer Daley, and Shukri Khuri. “Transthoracic versus transhiatal esophagectomy: a prospective study of 945 patients.” J Thorac Cardiovasc Surg 125, no. 5 (May 2003): 1114–20. https://doi.org/10.1067/mtc.2003.315.
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  - Kinch, Michael S., Mary-Beth Moore, and David H. Harpole. “Predictive value of the EphA2 receptor tyrosine kinase in lung cancer recurrence and survival.” Clin Cancer Res 9, no. 2 (February 2003): 613–18.
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  - Bailey, Stephen H., David A. Bull, David H. Harpole, Jeffrey J. Rentz, Leigh A. Neumayer, Theodore N. Pappas, Jennifer Daley, William G. Henderson, Barbara Krasnicka, and Shukri F. Khuri. “Outcomes after esophagectomy: a ten-year prospective cohort.” Ann Thorac Surg 75, no. 1 (January 2003): 217–22. https://doi.org/10.1016/s0003-4975(02)04368-0.
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  - Joshi, Mary-Beth Moore, Thomas A. D’Amico, and David H. Harpole. “Molecular biologic substaging of stage I NSCLC through immunohistochemistry performed on formalin-fixed, paraffin-embedded tissue.” Methods Mol Med 75 (2003): 369–88.
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  - Toloza, Eric M., and David H. Harpole. “Intraoperative techniques to prevent air leaks.” Chest Surg Clin N Am 12, no. 3 (August 2002): 489–505. https://doi.org/10.1016/s1052-3359(02)00020-0.
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  - D’Amico, Thomas A., Terence Z. Wong, David H. Harpole, Stephen D. Brown, and R Edward Coleman. “Impact of computed tomography-positron emission tomography fusion in staging patients with thoracic malignancies.” Ann Thorac Surg 74, no. 1 (July 2002): 160–63. https://doi.org/10.1016/s0003-4975(02)03693-7.
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  - Lau, Christine L., Mary-Beth H. Moore, Kelly R. Brooks, Thomas A. D’Amico, and David H. Harpole. “Molecular staging of lung and esophageal cancer.” Surg Clin North Am 82, no. 3 (June 2002): 497–523. https://doi.org/10.1016/s0039-6109(02)00024-5.
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  - Lewis, Cleveland W., and David Harpole. “Pulmonary metastasectomy for metastatic malignant melanoma.” Semin Thorac Cardiovasc Surg 14, no. 1 (January 2002): 45–48. https://doi.org/10.1053/stcs.2002.31741.
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  - Kelley, M. J., S. Li, and D. H. Harpole. “Genetic analysis of the beta-tubulin gene, TUBB, in non-small-cell lung cancer.” J Natl Cancer Inst 93, no. 24 (December 19, 2001): 1886–88. https://doi.org/10.1093/jnci/93.24.1886.
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  - D’Amico, T. A., T. A. Aloia, M. B. Moore, D. H. Conlon, J. E. Herndon, M. S. Kinch, and D. H. Harpole. “Predicting the sites of metastases from lung cancer using molecular biologic markers.” Ann Thorac Surg 72, no. 4 (October 2001): 1144–48. https://doi.org/10.1016/s0003-4975(01)02979-4.
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  - Aloia, T. A., D. H. Harpole, C. E. Reed, C. Allegra, M. B. Moore, J. E. Herndon, and T. A. D’Amico. “Tumor marker expression is predictive of survival in patients with esophageal cancer.” Ann Thorac Surg 72, no. 3 (September 2001): 859–66. https://doi.org/10.1016/s0003-4975(01)02838-7.
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  - Marom, E. M., T. A. Aloia, M. B. Moore, M. Hara, J. E. Herndon, D. H. Harpole, P. C. Goodman, and E. F. Patz. “Correlation of FDG-PET imaging with Glut-1 and Glut-3 expression in early-stage non-small cell lung cancer.” Lung Cancer 33, no. 2–3 (August 2001): 99–107. https://doi.org/10.1016/s0169-5002(00)00250-6.
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  - Salgia, R., D. Harpole, J. E. Herndon, E. Pisick, A. Elias, and A. T. Skarin. “Role of serum tumor markers CA 125 and CEA in non-small cell lung cancer.” Anticancer Research 21, no. 2 B (June 11, 2001): 1241–46.
  - Harris, L. N., V. Liotcheva, G. Broadwater, M. J. Ramirez, P. Maimonis, S. Anderson, T. Everett, et al. “Comparison of methods of measuring HER-2 in metastatic breast cancer patients treated with high-dose chemotherapy.” J Clin Oncol 19, no. 6 (March 15, 2001): 1698–1706. https://doi.org/10.1200/JCO.2001.19.6.1698.
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  - Harpole, D. H., M. B. Moore, J. E. Herndon, T. Aloia, T. A. D’Amico, T. Sporn, A. Parr, I. Linoila, and C. Allegra. “The prognostic value of molecular marker analysis in patients treated with trimodality therapy for esophageal cancer.” Clin Cancer Res 7, no. 3 (March 2001): 562–69.
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  - Aloia, T., G. Bepler, D. Harpole, P. C. Goodman, H. P. McAdams, J. J. Erasmus, J. E. Herndon, and E. F. Patz. “Integration of peripheral blood biomarkers with computed tomography to differentiate benign from malignant pulmonary opacities.” Cancer Detect Prev 25, no. 4 (2001): 336–43.
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  - Kawakami, K., J. Brabender, R. V. Lord, S. Groshen, B. D. Greenwald, M. J. Krasna, J. Yin, et al. “Hypermethylated APC DNA in plasma and prognosis of patients with esophageal adenocarcinoma.” J Natl Cancer Inst 92, no. 22 (November 15, 2000): 1805–11. https://doi.org/10.1093/jnci/92.22.1805.
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  - Lau, C. L., D. H. Harpole, and E. Patz. “Staging techniques for lung cancer.” Chest Surg Clin N Am 10, no. 4 (November 2000): 781–801.
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  - D’Amico, T. A., and D. H. Harpole. “Molecular biology of esophageal cancer.” Chest Surg Clin N Am 10, no. 3 (August 2000): 451–69.
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  - Patz, E. F., S. Rossi, D. H. Harpole, J. E. Herndon, and P. C. Goodman. “Correlation of tumor size and survival in patients with stage IA non-small cell lung cancer.” Chest 117, no. 6 (June 2000): 1568–71. https://doi.org/10.1378/chest.117.6.1568.
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  - D’Amico, T. A., T. A. Aloia, M. B. Moore, J. E. Herndon, K. R. Brooks, C. L. Lau, and D. H. Harpole. “Molecular biologic substaging of stage I lung cancer according to gender and histology.” Ann Thorac Surg 69, no. 3 (March 2000): 882–86. https://doi.org/10.1016/s0003-4975(99)01522-2.
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  - Lau, C. L., and D. H. Harpole. “Noninvasive clinical staging modalities for lung cancer.” Semin Surg Oncol 18, no. 2 (March 2000): 116–23. https://doi.org/10.1002/(sici)1098-2388(200003)18:2<116::aid-ssu5>3.0.co;2-l.
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  - “Rationale and design of The National Emphysema Treatment Trial: a prospective randomized trial of lung volume reduction surgery. The National Emphysema Treatment Trial Research Group.” Chest 116, no. 6 (December 1999): 1750–61. https://doi.org/10.1378/chest.116.6.1750.
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  - Grichnik, K. P., A. J. Ijsselmuiden, T. A. D’Amico, D. H. Harpole, W. D. White, J. A. Blumenthal, and M. F. Newman. “Cognitive decline after major noncardiac operations: a preliminary prospective study.” Ann Thorac Surg 68, no. 5 (November 1999): 1786–91. https://doi.org/10.1016/s0003-4975(99)00992-3.
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  - Rodarte, J., C. Miller, P. Barnard, J. Carter, K. DuBose, D. Harpole, and al et. “Rationale and design of the national emphysema treatment trial (NETT): A prospective randomized trial of lung volume reduction surgery.” Edited by J. Rodarte, C. Miller, P. Barnard, J. Carter, K. DuBose, and D. Harpole. The Journal of Thoracic and Cardiovascular Surgery 118, no. 3 (September 1999): 518–28. https://doi.org/10.1016/S0022-5223(99)70191-1.
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  - D’Amico, T. A., M. Massey, J. E. Herndon, M. B. Moore, and D. H. Harpole. “A biologic risk model for stage I lung cancer: immunohistochemical analysis of 408 patients with the use of ten molecular markers.” J Thorac Cardiovasc Surg 117, no. 4 (April 1999): 736–43. https://doi.org/10.1016/s0022-5223(99)70294-1.
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  - Kwiatkowski, D. J., D. H. Harpole, J. Godleski, J. E. Herndon, D. B. Shieh, W. Richards, R. Blanco, H. J. Xu, G. M. Strauss, and D. J. Sugarbaker. “Molecular pathologic substaging in 244 stage I non-small-cell lung cancer patients: clinical implications.” J Clin Oncol 16, no. 7 (July 1998): 2468–77. https://doi.org/10.1200/JCO.1998.16.7.2468.
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  - Clary, B., L. Skaryak, M. Tedder, A. Hilton, G. Botz, and D. Harpole. “Methemoglobinemia complicating topical anesthesia during bronchoscopic procedures.” J Thorac Cardiovasc Surg 114, no. 2 (August 1997): 293–95. https://doi.org/10.1016/S0022-5223(97)70163-6.
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  - Harpole, D. H., S. A. Gall, W. G. Wolfe, J. S. Rankin, and R. H. Jones. “Effects of valve replacement on ventricular mechanics in mitral regurgitation and aortic stenosis.” Ann Thorac Surg 62, no. 3 (September 1996): 756–61. https://doi.org/10.1016/s0003-4975(96)00378-5.
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  - Jaklitsch, M. T., M. M. DeCamp, M. J. Liptay, D. H. Harpole, S. J. Swanson, S. J. Mentzer, and D. J. Sugarbaker. “Video-assisted thoracic surgery in the elderly. A review of 307 cases.” Chest 110, no. 3 (September 1996): 751–58. https://doi.org/10.1378/chest.110.3.751.
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  - Sugarbaker, D. J., J. P. Garcia, W. G. Richards, D. H. Harpole, E. Healy-Baldini, M. M. DeCamp, S. J. Mentzer, M. J. Liptay, G. M. Strauss, and S. J. Swanson. “Extrapleural pneumonectomy in the multimodality therapy of malignant pleural mesothelioma. Results in 120 consecutive patients.” Ann Surg 224, no. 3 (September 1996): 288–94. https://doi.org/10.1097/00000658-199609000-00005.
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  - Harpole, D. H., W. G. Richards, J. E. Herndon, and D. J. Sugarbaker. “Angiogenesis and molecular biologic substaging in patients with stage I non-small cell lung cancer.” Ann Thorac Surg 61, no. 5 (May 1996): 1470–76. https://doi.org/10.1016/0003-4975(96)00104-X.
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  - Harpole, D. H., J. E. Herndon, W. G. Young, W. G. Wolfe, and D. C. Sabiston. “Stage I nonsmall cell lung cancer. A multivariate analysis of treatment methods and patterns of recurrence.” Cancer 76, no. 5 (September 1, 1995): 787–96. https://doi.org/10.1002/1097-0142(19950901)76:5<787::aid-cncr2820760512>3.0.co;2-q.
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  - DeCamp, M. M., M. T. Jaklitsch, S. J. Mentzer, D. H. Harpole, and D. J. Sugarbaker. “The safety and versatility of video-thoracoscopy: a prospective analysis of 895 consecutive cases.” J Am Coll Surg 181, no. 2 (August 1995): 113–20.
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  - Harpole, D. H., J. R. Marks, W. G. Richards, J. E. Herndon, and D. J. Sugarbaker. “Localized adenocarcinoma of the lung: oncogene expression of erbB-2 and p53 in 150 patients.” Clin Cancer Res 1, no. 6 (June 1995): 659–64.
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  - Strauss, G. M., D. J. Kwiatkowski, D. H. Harpole, T. J. Lynch, A. T. Skarin, and D. J. Sugarbaker. “Molecular and pathologic markers in stage I non-small-cell carcinoma of the lung.” J Clin Oncol 13, no. 5 (May 1995): 1265–79. https://doi.org/10.1200/JCO.1995.13.5.1265.
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  - Harpole, D. H., J. E. Herndon, W. G. Wolfe, J. D. Iglehart, and J. R. Marks. “A prognostic model of recurrence and death in stage I non-small cell lung cancer utilizing presentation, histopathology, and oncoprotein expression.” Cancer Res 55, no. 1 (January 1, 1995): 51–56.
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  - Jaklitsch, M. T., D. H. Harpole, E. A. Healey, and D. J. Sugarbaker. “Current Issues in the Staging of Esophageal Cancer.” Semin Radiat Oncol 4, no. 3 (July 1994): 135–45. https://doi.org/10.1053/SRAO00400135.
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  - Harpole, D. H., and R. H. Jones. “Left ventricular function under stress before and after myocardial revascularization.” Am Heart J 124, no. 2 (August 1992): 273–79. https://doi.org/10.1016/0002-8703(92)90587-l.
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  - Harpole, D. H., J. M. Feldman, S. Buchanan, W. G. Young, and W. G. Wolfe. “Bronchial carcinoid tumors: a retrospective analysis of 126 patients.” Ann Thorac Surg 54, no. 1 (July 1992): 50–54. https://doi.org/10.1016/0003-4975(92)91139-z.
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  - Harpole, D. H., C. M. Johnson, W. G. Wolfe, S. L. George, and H. F. Seigler. “Analysis of 945 cases of pulmonary metastatic melanoma.” J Thorac Cardiovasc Surg 103, no. 4 (April 1992): 743–48.
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  - Harpole, D. H., C. J. Davidson, T. N. Skelton, K. B. Kisslo, R. H. Jones, and T. M. Bashore. “Early and late changes in left ventricular systolic performance after percutaneous aortic balloon valvuloplasty.” Am J Cardiol 66, no. 3 (August 1, 1990): 327–32. https://doi.org/10.1016/0002-9149(90)90844-q.
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  - Harpole, D. H., J. S. Rankin, W. G. Wolfe, F. M. Clements, P. Van Trigt, W. G. Young, and R. H. Jones. “Effects of standard mitral valve replacement on left ventricular function.” Ann Thorac Surg 49, no. 6 (June 1990): 866–73. https://doi.org/10.1016/0003-4975(90)90858-4.
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  - Harpole, D. H., C. J. Davidson, T. N. Skelton, K. B. Kisslo, R. H. Jones, and T. M. Bashore. “Changes in left ventricular systolic performance immediately after percutaneous aortic balloon valvuloplasty.” Am J Cardiol 65, no. 18 (May 15, 1990): 1213–18. https://doi.org/10.1016/0002-9149(90)90976-8.
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  - Harpole, D. H., and R. H. Jones. “Serial assessment of ventricular performance after valve replacement for aortic stenosis.” J Thorac Cardiovasc Surg 99, no. 4 (April 1990): 645–50.
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  - Clements, F. M., D. H. Harpole, T. Quill, R. H. Jones, and R. L. McCann. “Estimation of left ventricular volume and ejection fraction by two-dimensional transoesophageal echocardiography: comparison of short axis imaging and simultaneous radionuclide angiography.” Br J Anaesth 64, no. 3 (March 1990): 331–36. https://doi.org/10.1093/bja/64.3.331.
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  - Harpole, D. H., C. Davidson, T. Skelton, R. H. Jones, and T. M. Bashore. “Serial evaluation of ventricular function after percutaneous aortic balloon valvuloplasty.” Am Heart J 119, no. 1 (January 1990): 130–35. https://doi.org/10.1016/s0002-8703(05)80092-4.
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  - Harpole, D. H., J. S. Rankin, W. G. Wolfe, L. R. Smith, W. G. Young, F. M. Clements, and R. H. Jones. “Assessment of left ventricular functional preservation during isolated cardiac valve operations.” Circulation 80, no. 5 Pt 2 (November 1989): III1–9.
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  - Harpole, D. H., F. M. Clements, T. Quill, W. G. Wolfe, R. H. Jones, and R. L. McCann. “Right and left ventricular performance during and after abdominal aortic aneurysm repair.” Ann Surg 209, no. 3 (March 1989): 356–62. https://doi.org/10.1097/00000658-198903000-00017.
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  - Davidson, C. J., D. A. Harpole, K. Kisslo, T. N. Skelton, J. Kisslo, R. H. Jones, and T. M. Bashore. “Analysis of the early rise in aortic transvalvular gradient after aortic valvuloplasty.” Am Heart J 117, no. 2 (February 1989): 411–17. https://doi.org/10.1016/0002-8703(89)90788-6.
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  - Harpole, D. H., C. Bigelow, W. G. Young, W. G. Wolfe, and D. C. Sabiston. “Alveolar cell carcinoma of the lung: a retrospective analysis of 205 patients.” Ann Thorac Surg 46, no. 5 (November 1988): 502–7. https://doi.org/10.1016/s0003-4975(10)64685-1.
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  - Wanebo, H. J., P. H. Cooper, D. V. Young, D. H. Harpole, and D. L. Kaiser. “Prognostic factors in head and neck melanoma. Effect of lesion location.” Cancer 62, no. 4 (August 15, 1988): 831–37. https://doi.org/10.1002/1097-0142(19880815)62:4<831::aid-cncr2820620432>3.0.co;2-x.
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  - Wanebo, H. J., D. Harpole, and C. D. Teates. “Radionuclide lymphoscintigraphy with technetium 99m antimony sulfide colloid to identify lymphatic drainage of cutaneous melanoma at ambiguous sites in the head and neck and trunk.” Cancer 55, no. 6 (March 15, 1985): 1403–13. https://doi.org/10.1002/1097-0142(19850315)55:6<1403::aid-cncr2820550640>3.0.co;2-k.
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  - OCHSNER, A., and D. H. HARPOLE. “Malignant melanoma. Its prognosis as influenced by therapy.” Ann Surg 155 (May 1962): 629–38. https://doi.org/10.1097/00000658-196205000-00002.
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  - Welp, Annalyn M., Sarah E. Abbott, Pamela Samson, Robert B. Cameron, Lorraine D. Cornwell, David Harpole, and Drew Moghanaki. “The Quality of Peer-Reviewed Publications on Surgery for Early Stage Lung Cancer Within the Veterans Health Administration.” Semin Thorac Cardiovasc Surg 32, no. 4 (n.d.): 1066–73. https://doi.org/10.1053/j.semtcvs.2020.04.004.
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- Book Sections
  - Tong, B. C., and D. H. Harpole. “Molecular prognostication of lung cancer.” In Principles and Practice of Lung Cancer: The Official Reference Text of the International Association for the Study of Lung Cancer (IASLC): Fourth Edition, 147–62, 2012.
  - Harpole, D. H., and M. Onaitis. “Present concepts in the molecular biology of lung cancer.” In General Thoracic Surgery: Seventh Edition, 2–2:3577–91, 2011.
  - Meyerson, S. L., and D. A. Harpole. “Mycotic and actinomycetic infections of the lung.” In General Thoracic Surgery: Seventh Edition, 1–2:3077–3128, 2011.
  - Meyerson, S. L., and D. A. Harpole. “Anatomy of the thorax.” In General Thoracic Surgery: Seventh Edition, 1–2:76–102, 2011.
  - Meyerson, S. L., and D. H. Harpole. “Induction therapy for stage IIIA (N2) lung cancer.” In Difficult Decisions in Thoracic Surgery: An Evidence-Based Approach, 88–93, 2007. https://doi.org/10.1007/978-1-84628-474-8_10.
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- Other Articles
  - Burt, Brian, Brian Kubasiak, and David H. Harpole. “Value of circulating insulin-like growth factor-associated proteins for the detection of stage I non-small cell lung cancer Discussion.” Journal of Thoracic and Cardiovascular Surgery. MOSBY-ELSEVIER, March 1, 2015.
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  - Rao, Vivek, Kindi Al, David H. Harpole, and Todd K. Rosengart. “Sustained release of milrinone delivered via microparticles in a rodent model of myocardial infarction Discussion.” Journal of Thoracic and Cardiovascular Surgery. MOSBY-ELSEVIER, November 1, 2014.
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  - Coles, John G., Kim Mr, Peter Mckeown, David H. Harpole, and Carl L. Backer. “Patient Genotypes Impact Survival After Surgery for Isolated Congenital Heart Disease DISCUSSION.” Annals of Thoracic Surgery. ELSEVIER SCIENCE INC, July 1, 2014.
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  - Harpole, David H., Scott J. Swanson, Ginsburg Dr, Akif Turna, and Malcolm M. Decamp. “Lung Volume Reduction Surgery Using the NETT Selection Criteria DISCUSSION.” Annals of Thoracic Surgery. ELSEVIER SCIENCE INC, May 1, 2011.
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  - Potti, Anil, Sayan Mukherjee, Rebecca Petersen, Holly K. Dressman, Andrea Bild, Jason Koontz, Robert Kratzke, et al. “Retraction: A genomic strategy to refine prognosis in early-stage non-small-cell lung cancer. N Engl J Med 2006;355:570-80.” N Engl J Med, March 24, 2011. https://doi.org/10.1056/NEJMc1101915.
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  - Berry, M. F., Z. Atkins, B. C. Tong, D. H. Harpole, T. A. D’Amico, and M. W. Onaitis. “A comprehensive evaluation for aspiration after esophagectomy reduces the incidence of postoperative pneumonia.” Dysphagia, 2011. https://doi.org/10.1007/s00455-011-9343-3.
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  - “Retraction. Pharmacogenomic strategies provide a rational approach to the treatment of cisplatin-resistant patients with advanced cancer. J Clin Oncol 25:4350–7, 2007.” J Clin Oncol, December 10, 2010. https://doi.org/10.1200/JCO.2010.33.7311.
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  - Krasna, Mark J., Mark J. Kim, David H. Harpole, Paul Henry Schipper, and Donald E. Low. “Pathologic T0N1 Esophageal Cancer After Neoadjuvant Therapy and Surgery: An Orphan Status DISCUSSION.” Annals of Thoracic Surgery. ELSEVIER SCIENCE INC, September 1, 2010.
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  - Swanson, Scott J., Scott J. Seely, David H. Harpole, and Mark I. Block. “Systematic Classification of Morbidity and Mortality After Thoracic Surgery DISCUSSION.” Annals of Thoracic Surgery. ELSEVIER SCIENCE INC, September 1, 2010.
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  - Harpole, D. H., M. P. Poullis, M. M. Decamp, and S. C. Murthy. “Discussion.” Annals of Thoracic Surgery, January 1, 2010. https://doi.org/10.1016/j.athoracsur.2010.04.100.
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  - Krasna, M. J., D. H. Harpole, P. H. Schipper, and D. E. Low. “Discussion.” Annals of Thoracic Surgery, January 1, 2010. https://doi.org/10.1016/j.athoracsur.2010.03.116.
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  - Swanson, S. J., H. H. David, and M. I. Block. “Discussion.” Annals of Thoracic Surgery, January 1, 2010. https://doi.org/10.1016/j.athoracsur.2010.05.014.
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  - Kim, Woo Jin, Edwin K. Silverman, Eric Hoffman, Gerard J. Criner, Zab Mosenifar, Frank C. Sciurba, Barry J. Make, et al. “CT metrics of airway disease and emphysema in severe COPD.” Chest, August 2009. https://doi.org/10.1378/chest.08-2858.
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  - Pham, DuyKhanh, and David H. Harpole. “Stage I NSCLC: elucidating the prognostic factors.” Thorax, March 2009. https://doi.org/10.1136/thx.2008.105965.
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  - Potti, A., H. K. Dressman, A. Bild, R. F. Riedel, G. Chan, R. Sayer, J. Cragun, et al. “Corrigendum: Genomic signatures to guide the use of chemotherapeutics (Nature Medicine (2006) 12, (1294-1300)).” Nature Medicine, August 1, 2008. https://doi.org/10.1038/nm0808-889.
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  - Potti, A., H. K. Dressman, A. Bild, R. F. Riedel, G. Chan, R. Sayer, J. Cragun, et al. “Erratum: Genomic signatures to guide the use of chemotherapeutics (Nature (2006) 12, (1294-1300)).” Nature Medicine, November 1, 2007. https://doi.org/10.1038/nm1107-1388.
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  - Reed, C. E., D. H. Harpole, K. E. Posther, S. L. Woolson, R. J. Downey, and B. R. Meyers. “Results of ACOSOG Z0050 trial: The utility of FDG-PET in staging potentially operable non-small cell lung cancer (vol 126, pg 1943, 2003).” Journal of Thoracic and Cardiovascular Surgery. MOSBY-ELSEVIER, April 1, 2007.
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  - Potti, Anil, David H. Harpole, and Joseph R. Nevins. “Refining prognosis in non-small-cell lung cancer - Reply.” New England Journal of Medicine. MASSACHUSETTS MEDICAL SOC, January 11, 2007.
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  - Potti, Anil, Holly K. Dressman, Andrea Bild, Richard F. Riedel, Gina Chan, Robyn Sayer, Janiel Cragun, et al. “Genomic signatures to guide the use of chemotherapeutics.” Nat Med, November 2006. https://doi.org/10.1038/nm1491.
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  - Rice, David C., Jeremy J. Erasmus, Craig W. Stevens, Ara A. Vaporciyan, Judy S. Wu, Anne S. Tsao, Garrett L. Walsh, et al. “Extended surgical staging for potentially resectable malignant pleural mesothelioma.” Ann Thorac Surg, December 2005. https://doi.org/10.1016/j.athoracsur.2005.06.014.
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  - Vaporciyan, Ara A., Arlene M. Correa, David C. Rice, Jack A. Roth, W. R. Smythe, Stephen G. Swisher, Garrett L. Walsh, and Joe B. Putnam. “Risk factors associated with atrial fibrillation after noncardiac thoracic surgery: analysis of 2588 patients.” J Thorac Cardiovasc Surg, March 2004. https://doi.org/10.1016/j.jtcvs.2003.07.011.
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  - Nguyen, Dao M., G Aaron Chen, Rishindra Reddy, Wilson Tsai, William D. Schrump, George Cole, and David S. Schrump. “Potentiation of paclitaxel cytotoxicity in lung and esophageal cancer cells by pharmacologic inhibition of the phosphoinositide 3-kinase/protein kinase B (Akt)-mediated signaling pathway.” J Thorac Cardiovasc Surg, February 2004. https://doi.org/10.1016/j.jtcvs.2003.09.033.
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  - Mackensen, G. B., L. K. Ti, B. G. Phillips-Bute, J. P. Mathew, M. F. Newman, H. P. Grocott, and H. P. Neurologic Outcome Research Group (NORG). “Cerebral embolization during cardiac surgery: impact of aortic atheroma burden.” Br J Anaesth, November 2003. https://doi.org/10.1093/bja/aeg234.
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  - Petre, Paul M., Frank A. Baciewicz, Stefan Tigan, and J Richard Spears. “Hyperbaric oxygen as a chemotherapy adjuvant in the treatment of metastatic lung tumors in a rat model.” J Thorac Cardiovasc Surg, January 2003. https://doi.org/10.1067/mtc.2003.90.
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  - Swaminathan, Madhav, Brian J. McCreath, Barbara G. Phillips-Bute, Mark F. Newman, Joseph P. Mathew, Peter K. Smith, James A. Blumenthal, Mark Stafford-Smith, and Mark Perioperative Outcomes Research Group. “Serum creatinine patterns in coronary bypass surgery patients with and without postoperative cognitive dysfunction.” Anesth Analg, July 2002. https://doi.org/10.1097/00000539-200207000-00001.
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  - Grigore, Alina M., Hilary P. Grocott, Joseph P. Mathew, Barbara Phillips-Bute, Timothy O. Stanley, Aimee Butler, Kevin P. Landolfo, et al. “The rewarming rate and increased peak temperature alter neurocognitive outcome after cardiac surgery.” Anesth Analg, January 2002. https://doi.org/10.1097/00000539-200201000-00002.
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  - Harpole, David H. “Invited commentary.” The Annals of Thoracic Surgery. Elsevier BV, August 2000. https://doi.org/10.1016/s0003-4975(00)01549-6.
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  - Kwiatkowski, D. J., D. H. Harpole, J. Godlewski, J. E. Herndon, D. B. Shieh, W. Richards, R. Blanco, H. J. Xu, G. M. Strauss, and D. J. Sugarbaker. “Molecular pathologic substaging in 244 stage I non-small-cell lung cancer patients: Clinical implications.” Pneumologie, December 1, 1999.
  - Harpole, D. H. “Prognostic significance of HER-2/neu overexpression in stage I adenocarcinoma of lung.” Annals of Thoracic Surgery. ELSEVIER SCIENCE INC, October 1, 1998.
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  - Miller, D. L., D. H. Harpole, and H. I. Pass. “Angiogenesis and molecular biologic substaging in patients with stage I non-small cell lung cancer - Discussion.” Annals of Thoracic Surgery. ELSEVIER SCIENCE INC, May 1, 1996.
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- Conference Papers
  - Raman, Vignesh, Oliver K. Jawitz, Chi-Fu Jeffrey Yang, Soraya L. Voigt, Thomas A. D’Amico, David H. Harpole, and Betty C. Tong. “The effect of extent of resection on outcomes in patients with limited stage small cell lung cancer.” In J Thorac Cardiovasc Surg, 161:1484-1492.e5, 2021. https://doi.org/10.1016/j.jtcvs.2020.02.135.
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  - Farrow, Norma E., Selena J. An, Paul J. Speicher, David H. Harpole, Thomas A. D’Amico, Jacob A. Klapper, Matthew G. Hartwig, and Betty C. Tong. “Disparities in guideline-concordant treatment for node-positive, non-small cell lung cancer following surgery.” In J Thorac Cardiovasc Surg, 160:261-271.e1, 2020. https://doi.org/10.1016/j.jtcvs.2019.10.102.
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  - Raman, Vignesh, Oliver K. Jawitz, Soraya L. Voigt, Chi-Fu J. Yang, David H. Harpole, Thomas A. D’Amico, and Matthew G. Hartwig. “The effect of age on survival after endoscopic resection versus surgery for T1a esophageal cancer.” In J Thorac Cardiovasc Surg, 160:295-302.e3, 2020. https://doi.org/10.1016/j.jtcvs.2019.11.050.
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  - Yu, Hui, Daniel T. Merrick, Ming-Sound Tsao, William G. Richards, Lucian R. Chirieac, Mark A. Watson, Christopher J. Rivard, et al. “Abstract 4550: Correlations between tumor mutation burden, inflammatory profile and histological characteristics of tumor microenvironment in early-stage squamous cell lung carcinoma.” In Tumor Biology. American Association for Cancer Research, 2019. https://doi.org/10.1158/1538-7445.sabcs18-4550.
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  - Kröhnert, M., R. Anderson, J. Bumberger, P. Dietrich, W. S. Harpole, and H. G. Maas. “Watching grass grow - A pilot study on the suitability of photogrammetric techniques for quantifying change in Aboveground Biomass in Grassland experiments.” In International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences Isprs Archives, 42:539–42, 2018. https://doi.org/10.5194/isprs-archives-XLII-2-539-2018.
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  - Maddula, Krishna, Mary-Beth Joshi, Vijay Modur, and David H. Harpole. “Abstract 1904: RNA expression based screening of ALK gene fusion from formalin fixed non-small cell lung cancer samples.” In Clinical Research (Excluding Clinical Trials). American Association for Cancer Research, 2014. https://doi.org/10.1158/1538-7445.am2014-1904.
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  - Grogan, Eric L., Stephen A. Deppen, Heidi Chen, Karla V. Ballman, Francys C. Verdial, Melinda C. Aldrich, Paul A. Decker, et al. “Abstract LB-296: FDG-PET avidity negatively impacts survival in pStage I NSCLC in the ACOSOG Z4031 trial.” In Clinical Research. American Association for Cancer Research, 2013. https://doi.org/10.1158/1538-7445.am2013-lb-296.
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  - Higgins, Kristin A., Neal E. Ready, Thomas A. D’amico, Mark W. Onaitis, Jeffrey Crawford, Robert Clough, Mark F. Berry, et al. “PERSISTENT N2 DISEASE AFTER NEOADJUVANT CHEMOTHERAPY-NOW WHAT?” In Journal of Thoracic Oncology, 6:S1572–S1572. LIPPINCOTT WILLIAMS & WILKINS, 2011.
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  - Joshi, Marybeth M., Loretta Erhunmwunsee, Debbi H. Conlon, and David H. Harpole. “NEIGHBORHOOD-LEVEL SOCIOECONOMIC (SES) DETERMINANTS NEGATIVELY IMPACT TREATMENT DECISIONS AMONG NON-SMALL CELL LUNG CANCER PATIENTS IN THE SOUTHEASTERN UNITED STATES.” In Journal of Thoracic Oncology, 6:S327–28. LIPPINCOTT WILLIAMS & WILKINS, 2011.
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  - Patel, P. R., S. Yoo, L. Marks, E. Miles, T. A. D’Amico, D. H. Harpole, and C. Kelsey. “The Effect of Increasing Experience with Intensity Modulated Radiation Therapy for Resected Malignant Pleural Mesothelioma.” In International Journal of Radiation Oncology*Biology*Physics, 78:S505–6. Elsevier BV, 2010. https://doi.org/10.1016/j.ijrobp.2010.07.1181.
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  - Erhunmwunsee, Loretta, Sandra S. Stinnett, and David H. Harpole. “Socioeconomic status predicts outcomes from NSCLC.” In Journal of Thoracic Oncology, 4:S310–11. LIPPINCOTT WILLIAMS & WILKINS, 2009.
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  - Gandara, David R., Philip C. Mack, Akiko Omori, Peter Grimminger, Mary-Beth M. Joshi, David H. Harpole, and Kathleen D. Danenberg. “Ribonucleotide reductase (RRM1) expression in non-small cell lung cancer (NSCLC): implications for personalizing gemcitabine-based therapy.” In Journal of Thoracic Oncology, 4:S401–2. LIPPINCOTT WILLIAMS & WILKINS, 2009.
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  - Gandara, David R., Philip C. Mack, Akiko Omori, Peter Grimminger, Primo N. Lara, Mary-Beth M. Joshi, David H. Harpole, and Kathleen D. Danenberg. “Thymidylate synthase (TS) RNA expression in non-small cell lung cancer (NSCLC): implications for personalizing pemetrexed therapy.” In Journal of Thoracic Oncology, 4:S400–S400. LIPPINCOTT WILLIAMS & WILKINS, 2009.
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  - Joshi, Mary-Beth M., Bruce Seligmann, and David H. Harpole. “Measurement of gene expression biomarkers by qNPA (TM) from archived NSCLC FFPE: prognosis of 5-year survival.” In Journal of Thoracic Oncology, 4:S502–S502. LIPPINCOTT WILLIAMS & WILKINS, 2009.
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  - Mack, Philip C., David R. Gandara, Akiko Omori, Peter P. Grimminger, Heinz-Josef Lenz, Mary-Beth M. Joshi, David H. Harpole, and Kathleeen D. Danenberg. “KRAS mutation analysis in non-small cell lung cancer (NSCLC) versus colorectal cancer (CRC): implications for EGFR-directed therapies.” In Journal of Thoracic Oncology, 4:S350–S350. LIPPINCOTT WILLIAMS & WILKINS, 2009.
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  - Erhunmwunsee, Loretta, Yun Lu, Xiaoyan Luo, David H. Harpole, Brigid L. M. Hogan, and Mark W. Onaitis. “Basal cells in lung cancer.” In Journal of the American College of Surgeons, 207:S30–S30. Elsevier BV, 2008. https://doi.org/10.1016/j.jamcollsurg.2008.06.053.
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  - Kelsey, C. R., J. A. Boyd, J. L. Hubbs, D. R. Hollis, J. Crawford, N. E. Ready, T. A. D’Amcio, D. H. Harpole, J. Garst, and L. B. Marks. “Local/regional recurrence following surgery for early-stage lung cancer: A 10-year experience with 975 patients.” In Journal of Clinical Oncology, Vol. 26. AMER SOC CLINICAL ONCOLOGY, 2008.
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  - Oh, D. S., J. Cooc, S. R. DeMeester, R. Mori, H. Kuramochi, C. Rizzetto, K. Danenberg, et al. “Molecular signature of esophageal adenocarcinoma derived from microarray analysis of paraffin-embedded specimens predicts systemic recurrence following resection.” In Journal of Clinical Oncology, Vol. 25. AMER SOC CLINICAL ONCOLOGY, 2007.
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  - Huening, M. A., D. W. Sevilla, A. Potti, D. H. Harpole, J. R. Nevins, and M. B. Datto. “A first step towards validating microarray gene expression profiling for clinical testing: Characterizing biological variance.” In Journal of Molecular Diagnostics, 8:660–660. AMER SOC INVESTIGATIVE PATHOLOGY, INC, 2006.
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  - Harpole, D. H., M. M. Joshi, R. P. Petersen, D. H. Conlon, K. Tanaka, D. Shimizu, H. Kuramochi, M. Williams, P. V. Danenberg, and K. Danenberg. “A lung cancer genomic risk prediction model derived from paraffin-embedded tissue.” In Journal of Clinical Oncology, 24:555S-555S. AMER SOC CLINICAL ONCOLOGY, 2006.
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  - Harpole, D. H., R. Petersen, S. Mukherjee, A. Bild, H. Dressman, R. Kratzke, M. J. Kelley, et al. “A genomic strategy to refine prognosis in early stage non-small cell lung carcinoma (NSCLC).” In Journal of Clinical Oncology, 24:370S-370S. AMER SOC CLINICAL ONCOLOGY, 2006.
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  - Joshi, M. M., R. P. Petersen, D. H. Conlon, K. Tanaka, D. Shimizu, H. Kuramochi, M. Williams, P. V. Danenberg, K. D. Danenberg, and D. H. Harpole. “Differential canonical pathways derived from microarrays using RNA from paraffin-embedded non-small cell lung cancer tissue.” In Journal of Clinical Oncology, 24:420S-420S. AMER SOC CLINICAL ONCOLOGY, 2006.
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  - Jaklitsch, M. T., L. Gu, D. H. Harpole, T. A. D’Amico, R. J. McKenna, M. J. Krasna, L. J. Kohman, S. J. Swanson, M. M. Decamp, and D. J. Sugarbaker. “Prospective phase II trial of pre-resection thoracoscopic (VATS) restaging following neoadjuvant therapy for IIIA(N2) non-small cell lung cancer (NSCLC): Results of CALGB 39803.” In Journal of Clinical Oncology, 23:636S-636S. AMER SOC CLINICAL ONCOLOGY, 2005.
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  - Petersen, R. P., A. Bild, H. Dressman, M. B. M. Joshi, D. H. Conlon, M. West, J. R. Nevins, and D. H. Harpole. “Gene expression signatures for prognosis in NSCLC, coupled with signatures of oncogenic pathway deregulation, provide a novel approach for selection of molecular targets.” In Journal of Clinical Oncology, 23:626S-626S. AMER SOC CLINICAL ONCOLOGY, 2005.
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  - Lemaire, Anthony, William R. Burfeind, Stafford S. Balderson, David H. Harpole, and Thomas A. D’Amico. “Tracheobronchial Stents in Selected Patients with Benign Airway Disease.” In Chest, 126:801S-801S. Elsevier BV, 2004. https://doi.org/10.1378/chest.126.4_meetingabstracts.801s.
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  - Strauss, G. M., J. E. Herndon, M. A. Maddaus, D. W. Johnstone, E. A. Johnson, D. H. Harpole, H. H. Gillenwater, et al. “A randomized clinical trial of adjuvant chemotherapy with paclitaxel and carboplatin following resection in stage IB non-small cell hung cancer (NSCLC): report of cancer and leukemia group b (CALGB) protocol 9633.” In Lung Cancer, 45:S75–76. ELSEVIER SCI IRELAND LTD, 2004.
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  - Strauss, Gary M., James E. Herndon, Michael A. Maddaus, David W. Johnstone, Elizabeth A. Johnson, David H. Harpole, Heidi H. Gillenwater, et al. “Randomized clinical trial of adjuvant chemotherapy with paclitaxel and carboplatin following resection in stage IB non-small cell lung cancer (NSCLC): Report of Cancer and Leukemia Group B (CALGB) Protocol 9633.” In Annals of Oncology, 15:13–14. OXFORD UNIV PRESS, 2004.
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  - Gaca, J. G., D. H. Harpole, T. A. D’Amico, T. Pappas, H. F. Seigler, W. G. Wolfe, and S. Tyler. “Pathologic nodal status predicts disease-free survival after neoadjuvant chemoradiation for gastroesophageal junction carcinoma.” In Gastroenterology, 123:1–2. W B SAUNDERS CO, 2002.
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  - Aloia, T., H. P. McAdams, G. Bepler, D. H. Harpole, P. C. Goodman, and E. F. Patz. “Integration of peripheral blood biomarkers with CT to differentiate benign from malignant pulmonary opacities.” In Radiology, 217:469–469. RADIOLOGICAL SOC NORTH AMER, 2000.
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  - Jaklitsch, M. T., M. M. Decamp, M. J. Liptay, D. H. Harpole, S. J. Swanson, S. J. Mentzer, and D. J. Sugarbaker. “Video-assisted thoracic surgery in the elderly. A review of 307 cases.” In International Congress of Thorax Surgery, edited by G. Antypas, 599–601. MONDUZZI EDITORE, 1997.
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  - HARPOLE, D. H. “RESECTION OF PULMONARY BULLOUS CYSTS WITH YAG LASER.” In Lasers in Surgery and Medicine, 8:195–195. WILEY-LISS, 1988.
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