David Harold Harpole Jr.

David Harold Harpole Jr.
Professor of Surgery

A. Non-small cell lung cancer
1. Evaluation of serum and tissue molecular biologic markers of recurrence in patients with a localize non-small cell lung cancer.
2. Molecular biologic staging of lymph nodes in patients with non-small cell lung cancer.
3. The evaluation of the clonality of metastatic tumors in patients with non-small cell lung cancer.

B. Clinical research activities
1. Creation of a prospective database for the Duke Thoracic Oncology Program.
2. A cost and satisfaction evaluation of thoracoscopy and open thoracotomy in patients.
3. Development of risk associated models of morbidity in patients undergoing general thoracic surgery procedures: The VA Cooperative Surgical Risk Study
4. A member of the Duke Gastrointestinal Malignancy Research Committee, developing esophageal cancer treatment protocols and outcome studies.

Current Appointments & Affiliations

Professor of Surgery, Surgery, Cardiovascular and Thoracic Surgery, Surgery 2003
Associate Professor in Pathology, Pathology, Clinical Science Departments 2005
Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 1987

Contact Information

Box 3627 Med Ctr, Durham, NC 27710
Hock Plaza-2424 Erwin Rd, Suite 403 Room 4017, Durham, NC 27705
david.harpole@duke.edu (919) 668-8413

Background
Education, Training, & Certifications
- Instructor of Surgery, Surgery, Harvard University - 1996
- M.D., University of Virginia 1984
Duke Appointment History
- Assistant Professor of Pathology, Pathology, Clinical Science Departments 2000 - 2005
- Associate Professor of Surgery, Surgery, Cardiovascular and Thoracic Surgery, Surgery 2000 - 2003
- Assistant Clinical Professor of Pathology, Pathology, Clinical Science Departments 1997 - 2000
- Associate Professor of Surgery, Surgery, Cardiovascular and Thoracic Surgery, Surgery 1997 - 2000
- Associate Clinical Professor of Surgery, Surgery, Cardiovascular and Thoracic Surgery, Surgery 1996 - 1997
- Instructor, Temporary in the Department of Surgery, Surgery, Cardiovascular and Thoracic Surgery, Surgery 1996
Research
Selected Grants
- Military Exposure-Related Pleural Mesothelioma: An Innovative Translational Approach to Inform Novel Molecular-Targeted Treatment Development awarded by Department of Defense 2017 - 2022
- Translational Research in Surgical Oncology awarded by National Institutes of Health 2002 - 2021
- myPlan Lung Cancer Test and Prediction of Chemotherapy Benefit awarded by Myriad Genetics, Inc. 2016 - 2021
- Prospective Validation of Prognostic and Predictive Molecular tests in Mesothelioma awarded by Brigham and Women's Hospital 2017 - 2018
- Lung Squamous Cell Carcinoma: Validation of Molecular Signatures of Prognosis awarded by University of Colorado - Denver 2012 - 2017
- Clinical Oncology Research Career Development Program awarded by National Institutes of Health 2009 - 2015
- GSK2302032A Antigen-Specific cancer Immunotherapeutic as adjuvant therapy in patients with Non-Small Cell Lung Cancer awarded by GlaxoSmithKline 2013 - 2015
- IPA - Joshi awarded by Veterans Administration Medical Center 2011 - 2013
- IPA - Debbie Conlon awarded by Durham Veterans Affairs Medical Center 2012 - 2013
- Validating Molecular Signature Risk Models of NSCLC awarded by National Institutes of Health 2006 - 2012
- Refining and Validating Genomic Signatures in Lung Cancer awarded by National Institutes of Health 2009 - 2010
- Prospective Validation of Genomic Signatures of Chemosensitivity in NSCLC awarded by National Institutes of Health 2009 - 2010
- Semiparametric ROC Curve Regression for Cancer Screening Studies awarded by National Institutes of Health 2007 - 2010
- Tissue and Serum Indicators of Lung Cancer awarded by National Institutes of Health 1996 - 2002
- Tissue And Serum Indicators Of Lung Cancer Recurrence awarded by National Institutes of Health 1996 - 1999
Publications & Artistic Works
Selected Publications
- Book Sections
  - Tong, BC, and Harpole, DH. "Molecular prognostication of lung cancer." In Principles and Practice of Lung Cancer: The Official Reference Text of the International Association for the Study of Lung Cancer (IASLC): Fourth Edition, 147-162. February 13, 2012.
  - Meyerson, SL, and Harpole, DH. "Induction therapy for stage IIIA (N2) lung cancer." In Difficult Decisions in Thoracic Surgery: An Evidence-Based Approach, 88-93. December 1, 2007. Full Text
- Conference Papers
  - Maddula, K, Joshi, M-B, Modur, V, and Harpole, DH. "Abstract 1904: RNA expression based screening of ALK gene fusion from formalin fixed non-small cell lung cancer samples." October 1, 2014. Full Text
  - Grogan, EL, Deppen, SA, Chen, H, Ballman, KV, Verdial, FC, Aldrich, MC, Decker, PA, Harpole, DH, Cerfolio, RJ, Keenan, RJ, Jones, DR, D'Amico, TA, Shrager, JB, Meyers, BF, and Putnam, JB. "Abstract LB-296: FDG-PET avidity negatively impacts survival in pStage I NSCLC in the ACOSOG Z4031 trial." April 15, 2013. Full Text
  - Higgins, KA, Ready, NE, D'amico, TA, Onaitis, MW, Crawford, J, Clough, R, Berry, MF, Yoo, D, Harpole, DH, Dunphy, F, and Kelsey, CR. "PERSISTENT N2 DISEASE AFTER NEOADJUVANT CHEMOTHERAPY-NOW WHAT?." June 2011. Link to Item
  - Joshi, MM, Erhunmwunsee, L, Conlon, DH, and Harpole, DH. "NEIGHBORHOOD-LEVEL SOCIOECONOMIC (SES) DETERMINANTS NEGATIVELY IMPACT TREATMENT DECISIONS AMONG NON-SMALL CELL LUNG CANCER PATIENTS IN THE SOUTHEASTERN UNITED STATES." June 2011. Link to Item
  - Patel, PR, Yoo, S, Marks, L, Miles, E, D'Amico, TA, Harpole, DH, and Kelsey, C. "The Effect of Increasing Experience with Intensity Modulated Radiation Therapy for Resected Malignant Pleural Mesothelioma." 2010. Full Text Link to Item
  - Erhunmwunsee, L, Stinnett, SS, and Harpole, DH. "Socioeconomic status predicts outcomes from NSCLC." September 2009. Link to Item
  - Gandara, DR, Mack, PC, Omori, A, Grimminger, P, Joshi, M-BM, Harpole, DH, and Danenberg, KD. "Ribonucleotide reductase (RRM1) expression in non-small cell lung cancer (NSCLC): implications for personalizing gemcitabine-based therapy." September 2009. Link to Item
  - Gandara, DR, Mack, PC, Omori, A, Grimminger, P, Lara, PN, Joshi, M-BM, Harpole, DH, and Danenberg, KD. "Thymidylate synthase (TS) RNA expression in non-small cell lung cancer (NSCLC): implications for personalizing pemetrexed therapy." September 2009. Link to Item
  - Joshi, M-BM, Seligmann, B, and Harpole, DH. "Measurement of gene expression biomarkers by qNPA (TM) from archived NSCLC FFPE: prognosis of 5-year survival." September 2009. Link to Item
  - Mack, PC, Gandara, DR, Omori, A, Grimminger, PP, Lenz, H-J, Joshi, M-BM, Harpole, DH, and Danenberg, KD. "KRAS mutation analysis in non-small cell lung cancer (NSCLC) versus colorectal cancer (CRC): implications for EGFR-directed therapies." September 2009. Link to Item
  - Erhunmwunsee, L, Lu, Y, Luo, X, Jr, HDH, Hogan, BLM, and Onaitis, MW. "Basal cells in lung cancer." September 2008. Full Text Link to Item
  - Kelsey, CR, Boyd, JA, Hubbs, JL, Hollis, DR, Crawford, J, Ready, NE, D'Amcio, TA, Harpole, DH, Garst, J, and Marks, LB. "Local/regional recurrence following surgery for early-stage lung cancer: A 10-year experience with 975 patients." May 20, 2008. Link to Item
  - Huening, MA, Sevilla, DW, Potti, A, Harpole, DH, Nevins, JR, and Datto, MB. "A first step towards validating microarray gene expression profiling for clinical testing: Characterizing biological variance." November 2006. Link to Item
  - Harpole, DH, Petersen, R, Mukherjee, S, Bild, A, Dressman, H, Kratzke, R, Kelley, MJ, Garst, J, Crawford, J, Nevins, JR, and Potti, A. "A genomic strategy to refine prognosis in early stage non-small cell lung carcinoma (NSCLC)." June 20, 2006. Link to Item
  - Joshi, MM, Petersen, RP, Conlon, DH, Tanaka, K, Shimizu, D, Kuramochi, H, Williams, M, Danenberg, PV, Danenberg, KD, and Jr, HDH. "Differential canonical pathways derived from microarrays using RNA from paraffin-embedded non-small cell lung cancer tissue." June 20, 2006. Link to Item
  - Jr, HDH, Joshi, MM, Petersen, RP, Conlon, DH, Tanaka, K, Shimizu, D, Kuramochi, H, Williams, M, Danenberg, PV, and Danenberg, K. "A lung cancer genomic risk prediction model derived from paraffin-embedded tissue." June 20, 2006. Link to Item
  - Jaklitsch, MT, Gu, L, Harpole, DH, D'Amico, TA, McKenna, RJ, Krasna, MJ, Kohman, LJ, Swanson, SJ, Decamp, MM, Sugarbaker, DJ, and Surg, CALGBT. "Prospective phase II trial of pre-resection thoracoscopic (VATS) restaging following neoadjuvant therapy for IIIA(N2) non-small cell lung cancer (NSCLC): Results of CALGB 39803." June 1, 2005. Link to Item
  - Petersen, RP, Bild, A, Dressman, H, Joshi, MBM, Conlon, DH, West, M, Nevins, JR, and Harpole, DH. "Gene expression signatures for prognosis in NSCLC, coupled with signatures of oncogenic pathway deregulation, provide a novel approach for selection of molecular targets." June 1, 2005. Link to Item
  - Lemaire, A, Burfeind, WR, Balderson, SS, Harpole, DH, and D'Amico, TA. "Tracheobronchial stents in selected patients with benign airway disease." October 2004. Full Text Link to Item
  - Strauss, GM, Herndon, JE, Maddaus, MA, Johnstone, DW, Johnson, EA, Harpole, DH, Gillenwater, HH, Watson, DM, Sugarbaker, DJ, Schilsky, RL, Vokes, EE, and CALGB, MRG. "A randomized clinical trial of adjuvant chemotherapy with paclitaxel and carboplatin following resection in stage IB non-small cell hung cancer (NSCLC): report of cancer and leukemia group b (CALGB) protocol 9633." September 2004. Link to Item
  - Strauss, GM, Herndon, JE, Maddaus, MA, Johnstone, DW, Johnson, EA, Harpole, DH, Gillenwater, HH, Watson, DM, Sugarbaker, DJ, Schilsky, RL, Vokes, EE, and Green, MR. "Randomized clinical trial of adjuvant chemotherapy with paclitaxel and carboplatin following resection in stage IB non-small cell lung cancer (NSCLC): Report of Cancer and Leukemia Group B (CALGB) Protocol 9633." 2004. Link to Item
  - Gaca, JG, Harpole, DH, D'Amico, TA, Pappas, T, Seigler, HF, Wolfe, WG, and Tyler, S. "Pathologic nodal status predicts disease-free survival after neoadjuvant chemoradiation for gastroesophageal junction carcinoma." July 2002. Link to Item
  - Aloia, T, McAdams, HP, Bepler, G, Harpole, DH, Goodman, PC, and Patz, EF. "Integration of peripheral blood biomarkers with CT to differentiate benign from malignant pulmonary opacities." November 2000. Link to Item
  - Jaklitsch, MT, Decamp, MM, Liptay, MJ, Harpole, DH, Swanson, SJ, Mentzer, SJ, and Sugarbaker, DJ. "Video-assisted thoracic surgery in the elderly. A review of 307 cases." 1997. Link to Item
  - HARPOLE, DH. "RESECTION OF PULMONARY BULLOUS CYSTS WITH YAG LASER." 1988. Link to Item
- Journal Articles
  - Yang, C-FJ, McSherry, F, Mayne, NR, Wang, X, Berry, MF, Tong, B, Harpole, DH, D'Amico, TA, Christensen, JD, Ready, NE, and Klapper, JA. "Surgical Outcomes After Neoadjuvant Chemotherapy and Ipilimumab for Non-Small-Cell Lung Cancer." The Annals of thoracic surgery (December 16, 2017). Full Text
  - Boyer, MJ, Williams, CD, Harpole, DH, Onaitis, MW, Kelley, MJ, and Salama, JK. "Improved Survival of Stage I Non-Small Cell Lung Cancer: A VA Central Cancer Registry Analysis." Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 12, no. 12 (December 2017): 1814-1823. Full Text
  - Yi, JS, Ready, N, Healy, P, Dumbauld, C, Osborne, R, Berry, M, Shoemaker, D, Clarke, J, Crawford, J, Tong, B, Harpole, D, D'Amico, TA, McSherry, F, Dunphy, F, McCall, SJ, Christensen, JD, Wang, X, and Weinhold, KJ. "Immune Activation in Early-Stage Non-Small Cell Lung Cancer Patients Receiving Neoadjuvant Chemotherapy Plus Ipilimumab." Clinical cancer research : an official journal of the American Association for Cancer Research 23, no. 24 (December 2017): 7474-7482. Full Text
  - Anderson, KL, Mulvihill, MS, Speicher, PJ, Yerokun, BA, Gulack, BC, Nussbaum, DP, Harpole, DH, D'Amico, TA, Berry, MF, and Hartwig, MG. "Adjuvant Chemotherapy Does Not Confer Superior Survival in Patients With Atypical Carcinoid Tumors." The Annals of thoracic surgery 104, no. 4 (October 2017): 1221-1230. Full Text
  - Yang, C-FJ, Kumar, A, Klapper, JA, Hartwig, MG, Tong, BC, Harpole, DH, Berry, MF, and D'Amico, TA. "A National Analysis of Long-term Survival Following Thoracoscopic Versus Open Lobectomy for Stage I Non-small-cell Lung Cancer." Annals of surgery (August 9, 2017). Full Text
  - Yao, XI, Wang, X, Speicher, PJ, Hwang, ES, Cheng, P, Harpole, DH, Berry, MF, Schrag, D, and Pang, HH. "Reporting and Guidelines in Propensity Score Analysis: A Systematic Review of Cancer and Cancer Surgical Studies." Journal of the National Cancer Institute 109, no. 8 (August 2017). (Review) Full Text
  - Yerokun, BA, Yang, C-FJ, Gulack, BC, Li, X, Mulvihill, MS, Gu, L, Wang, X, Harpole, DH, D'Amico, TA, Berry, MF, and Hartwig, MG. "A national analysis of wedge resection versus stereotactic body radiation therapy for stage IA non-small cell lung cancer." The Journal of thoracic and cardiovascular surgery 154, no. 2 (August 2017): 675-686.e4. Full Text
  - "Discussion." The Journal of Thoracic and Cardiovascular Surgery 153, no. 6 (June 2017): 1576-1578. Full Text
  - Yang, C-FJ, Chan, DY, Speicher, PJ, Gulack, BC, Tong, BC, Hartwig, MG, Kelsey, CR, D'Amico, TA, Berry, MF, and Harpole, DH. "Surgery Versus Optimal Medical Management for N1 Small Cell Lung Cancer." The Annals of thoracic surgery 103, no. 6 (June 2017): 1767-1772. Full Text
  - Yang, C-FJ, Chan, DY, Shah, SA, Yerokun, BA, Wang, XF, D'Amico, TA, Berry, MF, and Harpole, DH. "Long-term Survival After Surgery Compared With Concurrent Chemoradiation for Node-negative Small Cell Lung Cancer." Annals of surgery (May 4, 2017). Full Text
  - Cox, ML, Yang, C-FJ, Speicher, PJ, Anderson, KL, Fitch, ZW, Gu, L, Davis, RP, Wang, X, D'Amico, TA, Hartwig, MG, Harpole, DH, and Berry, MF. "The Role of Extent of Surgical Resection and Lymph Node Assessment for Clinical Stage I Pulmonary Lepidic Adenocarcinoma: An Analysis of 1991 Patients." Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 12, no. 4 (April 2017): 689-696. Full Text
  - Yang, C-FJ, Chan, DY, D’Amico, TA, Berry, MF, and Harpole, DH. "Reply to D.A. Palma." Journal of Clinical Oncology 35, no. 5 (February 10, 2017): 572-572. Full Text
  - Yang, C-FJ, Chan, DY, D'Amico, TA, Berry, MF, and Harpole, DH. "Reply to D.A. Palma." Journal of clinical oncology : official journal of the American Society of Clinical Oncology 35, no. 5 (February 2017): 572-. Full Text
  - Giattino, CM, Gardner, JE, Sbahi, FM, Roberts, KC, Cooter, M, Moretti, E, Browndyke, JN, Mathew, JP, Woldorff, MG, Berger, M, and MADCO-PC Investigators, . "Intraoperative Frontal Alpha-Band Power Correlates with Preoperative Neurocognitive Function in Older Adults." Frontiers in systems neuroscience 11 (January 2017): 24-. Full Text Open Access Copy
  - Torok, JA, Gu, L, Tandberg, DJ, Wang, X, Harpole, DH, Kelsey, CR, and Salama, JK. "Patterns of Distant Metastases After Surgical Management of Non-Small-cell Lung Cancer." Clinical lung cancer 18, no. 1 (January 2017): e57-e70. Full Text
  - Yang, C-FJ, Chan, DY, Wang, X, D'Amico, TA, Harpole, DH, and Berry, MF. "Reply to T.-H. Wang et al." Journal of clinical oncology : official journal of the American Society of Clinical Oncology 35, no. 1 (January 2017): 118-120. Full Text
  - Gulack, BC, Yang, C-FJ, Speicher, PJ, Yerokun, BA, Tong, BC, Onaitis, MW, D'Amico, TA, Harpole, DH, Hartwig, MG, and Berry, MF. "A Risk Score to Assist Selecting Lobectomy Versus Sublobar Resection for Early Stage Non-Small Cell Lung Cancer." The Annals of thoracic surgery 102, no. 6 (December 2016): 1814-1820. Full Text
  - Speicher, PJ, Fitch, ZW, Gulack, BC, Yang, C-FJ, Tong, BC, Harpole, DH, D'Amico, TA, Berry, MF, and Hartwig, MG. "Induction Chemotherapy is Not Superior to a Surgery-First Strategy for Clinical N1 Non-Small Cell Lung Cancer." The Annals of thoracic surgery 102, no. 3 (September 2016): 884-894. Full Text
  - Yang, C-FJ, Mayne, NR, Wang, H, Meyerhoff, RR, Hirji, S, Tong, BC, Hartwig, M, Harpole, D, D'Amico, TA, and Berry, M. "Outcomes of Major Lung Resection After Induction Therapy for Non-Small Cell Lung Cancer in Elderly Patients." The Annals of thoracic surgery 102, no. 3 (September 2016): 962-970. Full Text
  - Yang, C-FJ, Yan, BW, Meyerhoff, RR, Saud, SM, Gulack, BC, Speicher, PJ, Hartwig, MG, D'Amico, TA, Harpole, DH, and Berry, MF. "Impact of Age on Long-Term Outcomes of Surgery for Malignant Pleural Mesothelioma." Clinical lung cancer 17, no. 5 (September 2016): 419-426. Full Text
  - Yerokun, BA, Sun, Z, Yang, C-FJ, Gulack, BC, Speicher, PJ, Adam, MA, D'Amico, TA, Onaitis, MW, Harpole, DH, Berry, MF, and Hartwig, MG. "Minimally Invasive Versus Open Esophagectomy for Esophageal Cancer: A Population-Based Analysis." The Annals of thoracic surgery 102, no. 2 (August 2016): 416-423. Full Text
  - Harpole, DH. "The Integrated Comprehensive Care Program: A Novel Home Care Initiative After Major Thoracic Surgery." Seminars in thoracic and cardiovascular surgery 28, no. 2 (June 2016): 582-584. Full Text
  - Yang, C-FJ, Adil, SM, Anderson, KL, Meyerhoff, RR, Turley, RS, Hartwig, MG, Harpole, DH, Tong, BC, Onaitis, MW, D'Amico, TA, and Berry, MF. "Impact of patient selection and treatment strategies on outcomes after lobectomy for biopsy-proven stage IIIA pN2 non-small cell lung cancer." European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 49, no. 6 (June 2016): 1607-1613. Full Text
  - Yang, C-FJ, Meyerhoff, RR, Mayne, NR, Singhapricha, T, Toomey, CB, Speicher, PJ, Hartwig, MG, Tong, BC, Onaitis, MW, Harpole, DH, D'Amico, TA, and Berry, MF. "Long-term survival following open versus thoracoscopic lobectomy after preoperative chemotherapy for non-small cell lung cancer." European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 49, no. 6 (June 2016): 1615-1623. Full Text
  - Martin, LW, D'Cunha, J, Wang, X, Herzan, D, Gu, L, Abraham, N, Demmy, TL, Detterbeck, FC, Groth, SS, Harpole, DH, Krasna, MJ, Kernstine, K, Kohman, LJ, Patterson, GA, Sugarbaker, DJ, Vollmer, RT, Maddaus, MA, and Kratzke, RA. "Detection of Occult Micrometastases in Patients With Clinical Stage I Non-Small-Cell Lung Cancer: A Prospective Analysis of Mature Results of CALGB 9761 (Alliance)." Journal of clinical oncology : official journal of the American Society of Clinical Oncology 34, no. 13 (May 2016): 1484-1491. Full Text
  - Yang, C-FJ, Chan, DY, Speicher, PJ, Gulack, BC, Wang, X, Hartwig, MG, Onaitis, MW, Tong, BC, D'Amico, TA, Berry, MF, and Harpole, DH. "Role of Adjuvant Therapy in a Population-Based Cohort of Patients With Early-Stage Small-Cell Lung Cancer." Journal of clinical oncology : official journal of the American Society of Clinical Oncology 34, no. 10 (April 2016): 1057-1064. Full Text
  - Yang, C-FJ, Sun, Z, Speicher, PJ, Saud, SM, Gulack, BC, Hartwig, MG, Harpole, DH, Onaitis, MW, Tong, BC, D'Amico, TA, and Berry, MF. "Use and Outcomes of Minimally Invasive Lobectomy for Stage I Non-Small Cell Lung Cancer in the National Cancer Data Base." The Annals of thoracic surgery 101, no. 3 (March 2016): 1037-1042. Full Text
  - Scott, CD, and Harpole, DH. "The Biology of Pulmonary Metastasis." Thoracic surgery clinics 26, no. 1 (February 2016): 1-6. (Review) Full Text
  - Yang, C-FJ, Gulack, BC, Gu, L, Speicher, PJ, Wang, X, Harpole, DH, Onaitis, MW, D'Amico, TA, Berry, MF, and Hartwig, MG. "Adding radiation to induction chemotherapy does not improve survival of patients with operable clinical N2 non-small cell lung cancer." The Journal of thoracic and cardiovascular surgery 150, no. 6 (December 2015): 1484-1492. Full Text
  - Saunders, LR, Bankovich, AJ, Anderson, WC, Aujay, MA, Bheddah, S, Black, K, Desai, R, Escarpe, PA, Hampl, J, Laysang, A, Liu, D, Lopez-Molina, J, Milton, M, Park, A, Pysz, MA, Shao, H, Slingerland, B, Torgov, M, Williams, SA, Foord, O, Howard, P, Jassem, J, Badzio, A, Czapiewski, P, Harpole, DH, Dowlati, A, Massion, PP, Travis, WD, Pietanza, MC, Poirier, JT, Rudin, CM, Stull, RA, and Dylla, SJ. "A DLL3-targeted antibody-drug conjugate eradicates high-grade pulmonary neuroendocrine tumor-initiating cells in vivo." Science translational medicine 7, no. 302 (August 2015): 302ra136-. Full Text
  - Berry, MF, Yang, C-FJ, Hartwig, MG, Tong, BC, Harpole, DH, D'Amico, TA, and Onaitis, MW. "Impact of Pulmonary Function Measurements on Long-Term Survival After Lobectomy for Stage I Non-Small Cell Lung Cancer." The Annals of thoracic surgery 100, no. 1 (July 2015): 271-276. Full Text
  - Meyerhoff, RR, Yang, C-FJ, Speicher, PJ, Gulack, BC, Hartwig, MG, D'Amico, TA, Harpole, DH, and Berry, MF. "Impact of mesothelioma histologic subtype on outcomes in the Surveillance, Epidemiology, and End Results database." The Journal of surgical research 196, no. 1 (June 2015): 23-32. Full Text
  - Yang, C-FJ, Meyerhoff, RR, Stephens, SJ, Singhapricha, T, Toomey, CB, Anderson, KL, Kelsey, C, Harpole, D, D'Amico, TA, and Berry, MF. "Long-Term Outcomes of Lobectomy for Non-Small Cell Lung Cancer After Definitive Radiation Treatment." The Annals of thoracic surgery 99, no. 6 (June 2015): 1914-1920. Full Text
  - Little, AG, Lerut, AE, Harpole, DH, Hofstetter, WL, Mitchell, JD, Altorki, NK, and Krasna, MJ. "The Society of Thoracic Surgeons practice guidelines on the role of multimodality treatment for cancer of the esophagus and gastroesophageal junction." The Annals of thoracic surgery 98, no. 5 (November 2014): 1880-1885. (Review) Full Text
  - Malik, SM, Pazdur, R, Abrams, JS, Socinski, MA, Sause, WT, Harpole, DH, Welch, JJ, Korn, EL, Ullmann, CD, and Hirsch, FR. "Consensus report of a joint NCI thoracic malignancies steering committee: FDA workshop on strategies for integrating biomarkers into clinical development of new therapies for lung cancer leading to the inception of "master protocols" in lung cancer." Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 9, no. 10 (October 2014): 1443-1448. Full Text
  - Shah, AA, Worni, M, Onaitis, MW, Balderson, SS, Harpole, DH, D'Amico, TA, and Berry, MF. "Thoracoscopic left upper lobectomy in patients with internal mammary artery coronary bypass grafts." The Annals of thoracic surgery 98, no. 4 (October 2014): 1207-1212. Full Text
  - Klapper, J, Hirji, S, Hartwig, MG, D'Amico, TA, Harpole, DH, Onaitis, MW, and Berry, MF. "Outcomes after pneumonectomy for benign disease: the impact of urgent resection." Journal of the American College of Surgeons 219, no. 3 (September 2014): 518-524. Full Text
  - Tong, BC, Kosinski, AS, Burfeind, WR, Onaitis, MW, Berry, MF, Harpole, DH, and D'Amico, TA. "Sex differences in early outcomes after lung cancer resection: analysis of the Society of Thoracic Surgeons General Thoracic Database." The Journal of thoracic and cardiovascular surgery 148, no. 1 (July 2014): 13-18. Full Text
  - Grogan, EL, Deppen, SA, Ballman, KV, Andrade, GM, Verdial, FC, Aldrich, MC, Chen, CL, Decker, PA, Harpole, DH, Cerfolio, RJ, Keenan, RJ, Jones, DR, D'Amico, TA, Shrager, JB, Meyers, BF, and Putnam, JB. "Accuracy of fluorodeoxyglucose-positron emission tomography within the clinical practice of the American College of Surgeons Oncology Group Z4031 trial to diagnose clinical stage I non-small cell lung cancer." The Annals of thoracic surgery 97, no. 4 (April 2014): 1142-1148. Full Text
  - Haney, JC, Hanna, JM, Berry, MF, Harpole, DH, D'Amico, TA, Tong, BC, and Onaitis, MW. "Differential prognostic significance of extralobar and intralobar nodal metastases in patients with surgically resected stage II non-small cell lung cancer." The Journal of thoracic and cardiovascular surgery 147, no. 4 (April 2014): 1164-1168. Full Text
  - Berry, MF, Worni, M, Wang, X, Harpole, DH, D'Amico, TA, and Onaitis, MW. "Sleeve lobectomy for non-small cell lung cancer with N1 nodal disease does not compromise survival." Ann Thorac Surg 97, no. 1 (January 2014): 230-235. Full Text Link to Item
  - Jaklitsch, MT, Gu, L, Demmy, T, Harpole, DH, D'Amico, TA, McKenna, RJ, Krasna, MJ, Kohman, LJ, Swanson, SJ, DeCamp, MM, Wang, X, Barry, S, Sugarbaker, DJ, and CALGB Thoracic Surgeons, . "Prospective phase II trial of preresection thoracoscopic mediastinal restaging after neoadjuvant therapy for IIIA (N2) non-small cell lung cancer: results of CALGB Protocol 39803." J Thorac Cardiovasc Surg 146, no. 1 (July 2013): 9-16. Full Text Link to Item
  - Boylan, AM, Wang, XF, Ko, R, Watson, PM, Gu, L, Harpole, D, Bueno, R, Kelly, R, Kohman, L, and Kratzke, R. "Detection of human telomerase reverse transcriptase mRNA in cells obtained by lavage of the pleura is not associated with worse outcome in patients with stage I/II non-small cell lung cancer: Results from Cancer and Leukemia Group B 159902." Journal of Thoracic and Cardiovascular Surgery 146, no. 1 (2013): 206-211. Full Text
  - Erhunmwunsee, L, Joshi, M-BM, Conlon, DH, and Harpole, DH. "Neighborhood-level socioeconomic determinants impact outcomes in nonsmall cell lung cancer patients in the Southeastern United States." Cancer 118, no. 20 (October 15, 2012): 5117-5123. Full Text Link to Item
  - Cuneo, KC, Riedel, RF, Dodd, LG, Harpole, DH, and Kirsch, DG. "Pathologic complete response of a malignant peripheral nerve sheath tumor in the lung treated with neoadjuvant Ifosfamide and radiation therapy." J Clin Oncol 30, no. 28 (October 1, 2012): e291-e293. Full Text Link to Item
  - Ceppa, DP, Kosinski, AS, Berry, MF, Tong, BC, Harpole, DH, Mitchell, JD, D'Amico, TA, and Onaitis, MW. "Thoracoscopic lobectomy has increasing benefit in patients with poor pulmonary function: a Society of Thoracic Surgeons Database analysis." Ann Surg 256, no. 3 (September 2012): 487-493. Full Text Link to Item
  - Patel, PR, Yoo, S, Broadwater, G, Marks, LB, Miles, EF, D'Amico, TA, Harpole, D, and Kelsey, CR. "Effect of increasing experience on dosimetric and clinical outcomes in the management of malignant pleural mesothelioma with intensity-modulated radiation therapy." Int J Radiat Oncol Biol Phys 83, no. 1 (May 1, 2012): 362-368. Full Text Link to Item
  - Berry, MF, Onaitis, MW, Tong, BC, Balderson, SS, Harpole, DH, and D'Amico, TA. "Feasibility of hybrid thoracoscopic lobectomy and en-bloc chest wall resection." Eur J Cardiothorac Surg 41, no. 4 (April 2012): 888-892. Full Text Link to Item
  - Shah, AA, Barfield, ME, Kelsey, CR, Onaitis, MW, Tong, B, Harpole, D, D'Amico, TA, and Berry, MF. "Outcomes after surgical management of synchronous bilateral primary lung cancers." Ann Thorac Surg 93, no. 4 (April 2012): 1055-1060. Full Text Link to Item
  - Tong, BC, and Harpole, DH. "Molecular markers for incidence, prognosis, and response to therapy." Surg Oncol Clin N Am 21, no. 1 (January 2012): 161-175. Full Text Link to Item
  - Ceppa, DP, Welsby, IJ, Wang, TY, Onaitis, MW, Tong, BC, Harpole, DH, D'Amico, TA, and Berry, MF. "Perioperative management of patients on clopidogrel (Plavix) undergoing major lung resection." Ann Thorac Surg 92, no. 6 (December 2011): 1971-1976. Full Text Link to Item
  - D'Alonzo, RC, Bennett-Guerrero, E, Podgoreanu, M, D'Amico, TA, Harpole, DH, and Shaw, AD. "A randomized, double blind, placebo controlled clinical trial of the preoperative use of ketamine for reducing inflammation and pain after thoracic surgery." J Anesth 25, no. 5 (October 2011): 672-678. Full Text Link to Item
  - Berry, MF, Onaitis, MW, Tong, BC, Harpole, DH, and D'Amico, TA. "A model for morbidity after lung resection in octogenarians." Eur J Cardiothorac Surg 39, no. 6 (June 2011): 989-994. Full Text Link to Item
  - Swaminathan, M, Nicoara, A, Phillips-Bute, BG, Aeschlimann, N, Milano, CA, Mackensen, GB, Podgoreanu, MV, Velazquez, EJ, Stafford-Smith, M, Mathew, JP, and Cardiothoracic Anesthesia Research Endeavors (CARE) Group, . "Utility of a simple algorithm to grade diastolic dysfunction and predict outcome after coronary artery bypass graft surgery." Ann Thorac Surg 91, no. 6 (June 2011): 1844-1850. Full Text Link to Item
  - Onaitis, M, D'Amico, TA, Clark, CP, Guinney, J, Harpole, DH, and Rawlins, EL. "A 10-gene progenitor cell signature predicts poor prognosis in lung adenocarcinoma." Ann Thorac Surg 91, no. 4 (April 2011): 1046-1050. Full Text Link to Item
  - Berry, MF, Atkins, BZ, Tong, BC, Harpole, DH, D'Amico, TA, and Onaitis, MW. "A comprehensive evaluation for aspiration after esophagectomy reduces the incidence of postoperative pneumonia." J Thorac Cardiovasc Surg 140, no. 6 (December 2010): 1266-1271. Full Text Link to Item
  - Onaitis, M, D'Amico, T, Zhao, Y, O'Brien, S, and Harpole, D. "Risk factors for atrial fibrillation after lung cancer surgery: analysis of the Society of Thoracic Surgeons general thoracic surgery database." Ann Thorac Surg 90, no. 2 (August 2010): 368-374. Full Text Link to Item
  - Berry, MF, Villamizar-Ortiz, NR, Tong, BC, Burfeind, WR, Harpole, DH, D'Amico, TA, and Onaitis, MW. "Pulmonary function tests do not predict pulmonary complications after thoracoscopic lobectomy." Ann Thorac Surg 89, no. 4 (April 2010): 1044-1051. Full Text Link to Item
  - Burfeind, WR, Jaik, NP, Villamizar, N, Toloza, EM, Harpole, DH, and D'Amico, TA. "A cost-minimisation analysis of lobectomy: thoracoscopic versus posterolateral thoracotomy." Eur J Cardiothorac Surg 37, no. 4 (April 2010): 827-832. Full Text Link to Item
  - Paul, S, Altorki, NK, Sheng, S, Lee, PC, Harpole, DH, Onaitis, MW, Stiles, BM, Port, JL, and D'Amico, TA. "Thoracoscopic lobectomy is associated with lower morbidity than open lobectomy: a propensity-matched analysis from the STS database." J Thorac Cardiovasc Surg 139, no. 2 (February 2010): 366-378. Full Text Link to Item
  - Tong, BC, Hanna, J, Toloza, EM, Onaitis, MW, D'Amico, TA, Harpole, DH, and Burfeind, WR. "Outcomes of video-assisted thoracoscopic decortication." Ann Thorac Surg 89, no. 1 (January 2010): 220-225. Full Text Link to Item
  - Berry, MF, Hanna, J, Tong, BC, Burfeind, WR, Harpole, DH, D'Amico, TA, and Onaitis, MW. "Risk factors for morbidity after lobectomy for lung cancer in elderly patients." Ann Thorac Surg 88, no. 4 (October 2009): 1093-1099. Full Text Link to Item
  - Villamizar, NR, Darrabie, MD, Burfeind, WR, Petersen, RP, Onaitis, MW, Toloza, E, Harpole, DH, and D'Amico, TA. "Thoracoscopic lobectomy is associated with lower morbidity compared with thoracotomy." J Thorac Cardiovasc Surg 138, no. 2 (August 2009): 419-425. Full Text Link to Item
  - Onaitis, MW, Petersen, RP, Haney, JC, Saltz, L, Park, B, Flores, R, Rizk, N, Bains, MS, Dycoco, J, D'Amico, TA, Harpole, DH, Kemeny, N, Rusch, VW, and Downey, R. "Prognostic factors for recurrence after pulmonary resection of colorectal cancer metastases." Ann Thorac Surg 87, no. 6 (June 2009): 1684-1688. Full Text Link to Item
  - Joshi, MM, Seligmann, B, Sabalos, C, and Harpole, DH. "Measurement of gene expression biomarkers by qNPA from archived NSCLC FFPE: Prognosis of 5-year survival." Journal of clinical oncology : official journal of the American Society of Clinical Oncology 27, no. 15_suppl (May 2009): 11098-.
  - West, H, Harpole, D, and Travis, W. "Histologic considerations for individualized systemic therapy approaches for the management of non-small cell lung cancer." Chest 136, no. 4 (2009): 1112-1118. Full Text
  - West, H, Lilenbaum, R, Harpole, D, Wozniak, A, and Sequist, L. "Molecular analysis-based treatment strategies for the management of non-small cell lung cancer." Journal of Thoracic Oncology 4, no. 9 SUPPL. 2 (2009): S1029-S1039. Full Text
  - Jones, LW, Eves, ND, Peterson, BL, Garst, J, Crawford, J, West, MJ, Mabe, S, Harpole, D, Kraus, WE, and Douglas, PS. "Safety and feasibility of aerobic training on cardiopulmonary function and quality of life in postsurgical nonsmall cell lung cancer patients: a pilot study." Cancer 113, no. 12 (December 15, 2008): 3430-3439. Full Text Link to Item
  - Strauss, GM, Herndon, JE, Maddaus, MA, Johnstone, DW, Johnson, EA, Harpole, DH, Gillenwater, HH, Watson, DM, Sugarbaker, DJ, Schilsky, RL, Vokes, EE, and Green, MR. "Adjuvant paclitaxel plus carboplatin compared with observation in stage IB non-small-cell lung cancer: CALGB 9633 with the Cancer and Leukemia Group B, Radiation Therapy Oncology Group, and North Central Cancer Treatment Group Study Groups." J Clin Oncol 26, no. 31 (November 1, 2008): 5043-5051. Full Text Link to Item
  - Burfeind, WR, Tong, BC, O'Branski, E, Herndon, JE, Toloza, EM, D'Amico, TA, Harpole, LH, and Harpole, DH. "Quality of life outcomes are equivalent after lobectomy in the elderly." J Thorac Cardiovasc Surg 136, no. 3 (September 2008): 597-604. Full Text Link to Item
  - Kelsey, CR, Boyd, JA, Hubbs, JL, Hollis, DR, Crawford, J, Ready, NE, D'Amcio, TA, Harpole, DH, Garst, J, and Marks, LB. "Local/regional recurrence following surgery for early-stage lung cancer: A 10-year experience with 975 patients." J Clin Oncol 26, no. 15_suppl (May 20, 2008): 7542-. Link to Item
  - Boffa, DJ, Allen, MS, Grab, JD, Gaissert, HA, Harpole, DH, and Wright, CD. "Data from The Society of Thoracic Surgeons General Thoracic Surgery database: the surgical management of primary lung tumors." J Thorac Cardiovasc Surg 135, no. 2 (February 2008): 247-254. Full Text Link to Item
  - Atkins, BZ, Harpole, DH, Mangum, JH, Toloza, EM, D'Amico, TA, and Burfeind, WR. "Pulmonary segmentectomy by thoracotomy or thoracoscopy: reduced hospital length of stay with a minimally-invasive approach." Ann Thorac Surg 84, no. 4 (October 2007): 1107-1112. Full Text Link to Item
  - Hsu, DS, Balakumaran, BS, Acharya, CR, Vlahovic, V, Walters, KS, Garman, K, Anders, C, Riedel, RF, Lancaster, J, Harpole, D, Dressman, HK, Nevins, JR, Febbo, PG, and Potti, A. "Pharmacogenomic strategies provide a rational approach to the treatment of cisplatin-resistant patients with advanced cancer." J Clin Oncol 25, no. 28 (October 1, 2007): 4350-4357. Full Text Link to Item
  - Tong, BC, and Harpole, DH. "Audit, quality control, and performance in thoracic surgery: a North American perspective." Thorac Surg Clin 17, no. 3 (August 2007): 379-386. (Review) Full Text Link to Item
  - Loewen, GM, Watson, D, Kohman, L, Herndon, JE, Shennib, H, Kernstine, K, Olak, J, Mador, MJ, Harpole, D, Sugarbaker, D, Green, M, and Cancer and Leukemia Group B, . "Preoperative exercise Vo2 measurement for lung resection candidates: results of Cancer and Leukemia Group B Protocol 9238." J Thorac Oncol 2, no. 7 (July 2007): 619-625. Full Text Link to Item
  - Harpole, DH. "Prognostic modeling in early stage lung cancer: an evolving process from histopathology to genomics." Thorac Surg Clin 17, no. 2 (May 2007): 167-viii. (Review) Full Text Link to Item
  - Petersen, RP, Pham, D, Burfeind, WR, Hanish, SI, Toloza, EM, Harpole, DH, and D'Amico, TA. "Thoracoscopic lobectomy facilitates the delivery of chemotherapy after resection for lung cancer." Ann Thorac Surg 83, no. 4 (April 2007): 1245-1249. Full Text Link to Item
  - Czito, BG, Kelsey, CR, Hurwitz, HI, Willett, CG, Morse, MA, Blobe, GC, Fernando, NH, D'Amico, TA, Harpole, DH, Honeycutt, W, Yu, D, and Bendell, JC. "A Phase I study of capecitabine, carboplatin, and paclitaxel with external beam radiation therapy for esophageal carcinoma." Int J Radiat Oncol Biol Phys 67, no. 4 (March 15, 2007): 1002-1007. Full Text Link to Item
  - Petersen, RP, Hanish, SI, Haney, JC, Miller, CC, Burfeind, WR, Tyler, DS, Seigler, HF, Wolfe, W, D'Amico, TA, and Harpole, DH. "Improved survival with pulmonary metastasectomy: an analysis of 1720 patients with pulmonary metastatic melanoma." J Thorac Cardiovasc Surg 133, no. 1 (January 2007): 104-110. Full Text Link to Item
  - Petersen, RP, Campa, MJ, Sperlazza, J, Conlon, D, Joshi, M-B, Harpole, DH, and Patz, EF. "Tumor infiltrating Foxp3+ regulatory T-cells are associated with recurrence in pathologic stage I NSCLC patients." Cancer 107, no. 12 (December 15, 2006): 2866-2872. Full Text Link to Item
  - Harpole, DH, and Meyerson, SL. "Lung cancer staging: proteomics." Thorac Surg Clin 16, no. 4 (November 2006): 339-343. (Review) Full Text Link to Item
  - Lemaire, A, Nikolic, I, Petersen, T, Haney, JC, Toloza, EM, Harpole, DH, D'Amico, TA, and Burfeind, WR. "Nine-year single center experience with cervical mediastinoscopy: complications and false negative rate." Ann Thorac Surg 82, no. 4 (October 2006): 1185-1189. Full Text Link to Item
  - Posther, KE, McCall, LM, Harpole, DH, Reed, CE, Putnam, JB, Rusch, VW, and Siegel, BA. "Yield of brain 18F-FDG PET in evaluating patients with potentially operable non-small cell lung cancer." J Nucl Med 47, no. 10 (October 2006): 1607-1611. Link to Item
  - Onaitis, MW, Petersen, RP, Balderson, SS, Toloza, E, Burfeind, WR, Harpole, DH, and D'Amico, TA. "Thoracoscopic lobectomy is a safe and versatile procedure: experience with 500 consecutive patients." Ann Surg 244, no. 3 (September 2006): 420-425. Full Text Link to Item
  - Potti, A, Mukherjee, S, Petersen, R, Dressman, HK, Bild, A, Koontz, J, Kratzke, R, Watson, MA, Kelley, M, Ginsburg, GS, West, M, Harpole, DH, and Nevins, JR. "A genomic strategy to refine prognosis in early-stage non-small-cell lung cancer." N Engl J Med 355, no. 6 (August 10, 2006): 570-580. Full Text Link to Item
  - Petersen, RP, Pham, D, Toloza, EM, Burfeind, WR, Harpole, DH, Hanish, SI, and D'Amico, TA. "Thoracoscopic lobectomy: a safe and effective strategy for patients receiving induction therapy for non-small cell lung cancer." Ann Thorac Surg 82, no. 1 (July 2006): 214-218. Full Text Link to Item
  - Petersen, RP, and Harpole, DH. "Computed tomography screening for the early detection of lung cancer." J Natl Compr Canc Netw 4, no. 6 (July 2006): 591-594. (Review) Link to Item
  - Harpole, DH, Joshi, MM, Petersen, RP, Conlon, DH, Tanaka, K, Shimizu, D, Kuramochi, H, Williams, M, Danenberg, PV, and Danenberg, K. "A lung cancer genomic risk prediction model derived from paraffin-embedded tissue." J Clin Oncol 24, no. 18_suppl (June 20, 2006): 10059-. Link to Item
  - Joshi, MM, Petersen, RP, Conlon, DH, Tanaka, K, Shimizu, D, Kuramochi, H, Williams, M, Danenberg, PV, Danenberg, KD, and Harpole, DH. "Differential canonical pathways derived from microarrays using RNA from paraffin-embedded non-small cell lung cancer tissue." J Clin Oncol 24, no. 18_suppl (June 20, 2006): 7226-. Link to Item
  - D'Amico, TA, Brooks, KR, Joshi, M-BM, Conlon, D, Herndon, J, Petersen, RP, and Harpole, DH. "Serum protein expression predicts recurrence in patients with early-stage lung cancer after resection." Ann Thorac Surg 81, no. 6 (June 2006): 1982-1987. Full Text Link to Item
  - Harpole, DH, Petersen, R, Mukherjee, S, Bild, A, Dressman, H, Kratzke, R, Kelley, MJ, Garst, J, Crawford, J, Nevins, JR, and Potti, A. "A genomic strategy to refine prognosis in early stage non-small cell lung carcinoma (NSCLC)." Journal of clinical oncology : official journal of the American Society of Clinical Oncology 24, no. 18_suppl (June 2006): 7026-.
  - Allen, MS, Darling, GE, Pechet, TTV, Mitchell, JD, Herndon, JE, Landreneau, RJ, Inculet, RI, Jones, DR, Meyers, BF, Harpole, DH, Putnam, JB, Rusch, VW, and ACOSOG Z0030 Study Group, . "Morbidity and mortality of major pulmonary resections in patients with early-stage lung cancer: initial results of the randomized, prospective ACOSOG Z0030 trial." Ann Thorac Surg 81, no. 3 (March 2006): 1013-1019. Full Text Link to Item
  - Gaca, JG, Petersen, RP, Peterson, BL, Harpole, DH, D'Amico, TA, Pappas, TN, Seigler, HF, Wolfe, WG, and Tyler, DS. "Pathologic nodal status predicts disease-free survival after neoadjuvant chemoradiation for gastroesophageal junction carcinoma." Ann Surg Oncol 13, no. 3 (March 2006): 340-346. Full Text Link to Item
  - Posther, KE, and Harpole, DH. "The surgical management of lung cancer." Cancer Invest 24, no. 1 (February 2006): 56-67. (Review) Full Text Link to Item
  - Bild, AH, Yao, G, Chang, JT, Wang, Q, Potti, A, Chasse, D, Joshi, M-B, Harpole, D, Lancaster, JM, Berchuck, A, Olson, JA, Marks, JR, Dressman, HK, West, M, and Nevins, JR. "Oncogenic pathway signatures in human cancers as a guide to targeted therapies." Nature 439, no. 7074 (January 19, 2006): 353-357. Full Text Link to Item
  - Dressman, HK, Bild, A, Garst, J, Jr, DH, and Potti, A. "Genomic signatures in non-small-cell lung cancer: Targeting the targeted therapies." Current Oncology Reports 8, no. 4 (2006): 252-257. Full Text
  - Burfeind, WR, D'Amico, TA, Toloza, EM, Wolfe, WG, and Harpole, DH. "Low morbidity and mortality for bronchoplastic procedures with and without induction therapy." Ann Thorac Surg 80, no. 2 (August 2005): 418-421. Full Text Link to Item
  - Lemaire, A, Burfeind, WR, Toloza, E, Balderson, S, Petersen, RP, Harpole, DH, and D'Amico, TA. "Outcomes of tracheobronchial stents in patients with malignant airway disease." Ann Thorac Surg 80, no. 2 (August 2005): 434-437. Full Text Link to Item
  - Petersen, RP, Bild, A, Dressman, H, Joshi, MM, Conlon, DH, West, M, Nevins, JR, and Harpole, DH. "Gene expression signatures for prognosis in NSCLC, coupled with signatures of oncogenic pathway deregulation, provide a novel approach for selection of molecular targets." Journal of clinical oncology : official journal of the American Society of Clinical Oncology 23, no. 16_suppl (June 2005): 7020-.
  - D'Cunha, J, Herndon, JE, Herzan, DL, Patterson, GA, Kohman, LJ, Harpole, DH, Kernstine, KH, Kern, JA, Green, MR, Maddaus, MA, Kratzke, RA, and Cancer and Leukemia Group B, . "Poor correspondence between clinical and pathologic staging in stage 1 non-small cell lung cancer: results from CALGB 9761, a prospective trial." Lung Cancer 48, no. 2 (May 2005): 241-246. Full Text Link to Item
  - Joshi, M-BM, Shirota, Y, Danenberg, KD, Conlon, DH, Salonga, DS, Herndon, JE, Danenberg, PV, and Harpole, DH. "High gene expression of TS1, GSTP1, and ERCC1 are risk factors for survival in patients treated with trimodality therapy for esophageal cancer." Clin Cancer Res 11, no. 6 (March 15, 2005): 2215-2221. Full Text Link to Item
  - Burfeind, WR, and Harpole, DH. "Surgical strategies and outcomes after induction therapy for non-small cell lung cancer." Semin Thorac Cardiovasc Surg 17, no. 3 (2005): 186-190. (Review) Full Text Link to Item
  - Atkins, BZ, Shah, AS, Hutcheson, KA, Mangum, JH, Pappas, TN, Harpole, DH, and D'Amico, TA. "Reducing hospital morbidity and mortality following esophagectomy." Ann Thorac Surg 78, no. 4 (October 2004): 1170-1176. (Review) Full Text Link to Item
  - Allen, MS, Wood, DE, Hawkinson, RW, Harpole, DH, McKenna, RJ, Walsh, GL, Vallieres, E, Miller, DL, Nichols, FC, Smythe, WR, Davis, RD, and 3M Surgical Sealant Study Group, . "Prospective randomized study evaluating a biodegradable polymeric sealant for sealing intraoperative air leaks that occur during pulmonary resection." Ann Thorac Surg 77, no. 5 (May 2004): 1792-1801. Full Text Link to Item
  - Rizzo, M, Balderson, SS, Harpole, DH, and Levin, LS. "Thoracoscopic sympathectomy in the management of vasomotor disturbances and complex regional pain syndrome of the hand." Orthopedics 27, no. 1 (January 2004): 49-52. Link to Item
  - Gonzalez-Stawinski, GV, Lemaire, A, Merchant, F, O'Halloran, E, Coleman, RE, Harpole, DH, and D'Amico, TA. "A comparative analysis of positron emission tomography and mediastinoscopy in staging non-small cell lung cancer." J Thorac Cardiovasc Surg 126, no. 6 (December 2003): 1900-1905. Full Text Link to Item
  - Reed, CE, Harpole, DH, Posther, KE, Woolson, SL, Downey, RJ, Meyers, BF, Heelan, RT, MacApinlac, HA, Jung, S-H, Silvestri, GA, Siegel, BA, Rusch, VW, and American College of Surgeons Oncology Group Z0050 trial, . "Results of the American College of Surgeons Oncology Group Z0050 trial: the utility of positron emission tomography in staging potentially operable non-small cell lung cancer." J Thorac Cardiovasc Surg 126, no. 6 (December 2003): 1943-1951. Full Text Link to Item
  - Brooks, KR, To, K, Joshi, M-BM, Conlon, DH, Herndon, JE, D'Amico, TA, and Harpole, DH. "Measurement of chemoresistance markers in patients with stage III non-small cell lung cancer: a novel approach for patient selection." Ann Thorac Surg 76, no. 1 (July 2003): 187-193. Link to Item
  - Kinch, MS, Moore, M-B, and Harpole, DH. "Predictive value of the EphA2 receptor tyrosine kinase in lung cancer recurrence and survival." Clin Cancer Res 9, no. 2 (February 2003): 613-618. Link to Item
  - Bailey, SH, Bull, DA, Harpole, DH, Rentz, JJ, Neumayer, LA, Pappas, TN, Daley, J, Henderson, WG, Krasnicka, B, and Khuri, SF. "Outcomes after esophagectomy: a ten-year prospective cohort." Ann Thorac Surg 75, no. 1 (January 2003): 217-222. Link to Item
  - Joshi, M-BM, D'Amico, TA, and Harpole, DH. "Molecular biologic substaging of stage I NSCLC through immunohistochemistry performed on formalin-fixed, paraffin-embedded tissue." Methods Mol Med 75 (2003): 369-388. Link to Item
  - Rentz, J, Bull, D, Harpole, D, Bailey, S, Neumayer, L, Pappas, T, Krasnicka, B, Henderson, W, Daley, J, Khuri, S, Ehrman, W, Wood, D, Rentz, , and Rice, T. "Transthoracic versus transhiatal esophagectomy: A prospective study of 945 patients." Journal of Thoracic and Cardiovascular Surgery 125, no. 5 (2003): 1114-1120. Full Text
  - Toloza, EM, and Harpole, DH. "Intraoperative techniques to prevent air leaks." Chest Surg Clin N Am 12, no. 3 (August 2002): 489-505. (Review) Link to Item
  - D'Amico, TA, Wong, TZ, Harpole, DH, Brown, SD, and Coleman, RE. "Impact of computed tomography-positron emission tomography fusion in staging patients with thoracic malignancies." Ann Thorac Surg 74, no. 1 (July 2002): 160-163. Link to Item
  - Lau, CL, Moore, M-BH, Brooks, KR, D'Amico, TA, and Harpole, DH. "Molecular staging of lung and esophageal cancer." Surg Clin North Am 82, no. 3 (June 2002): 497-523. (Review) Link to Item
  - Lewis, CW, and Harpole, D. "Pulmonary metastasectomy for metastatic malignant melanoma." Semin Thorac Cardiovasc Surg 14, no. 1 (January 2002): 45-48. Link to Item
  - Kelley, MJ, Li, S, and Harpole, DH. "Genetic analysis of the beta-tubulin gene, TUBB, in non-small-cell lung cancer." J Natl Cancer Inst 93, no. 24 (December 19, 2001): 1886-1888. Link to Item
  - D'Amico, TA, Aloia, TA, Moore, MB, Conlon, DH, Herndon, JE, Kinch, MS, and Harpole, DH. "Predicting the sites of metastases from lung cancer using molecular biologic markers." Ann Thorac Surg 72, no. 4 (October 2001): 1144-1148. Link to Item
  - Aloia, TA, Harpole, DH, Reed, CE, Allegra, C, Moore, MB, Herndon, JE, and D'Amico, TA. "Tumor marker expression is predictive of survival in patients with esophageal cancer." Ann Thorac Surg 72, no. 3 (September 2001): 859-866. Link to Item
  - Marom, EM, Aloia, TA, Moore, MB, Hara, M, Herndon, JE, Harpole, DH, Goodman, PC, and Patz, EF. "Correlation of FDG-PET imaging with Glut-1 and Glut-3 expression in early-stage non-small cell lung cancer." Lung Cancer 33, no. 2-3 (August 2001): 99-107. Link to Item
  - Harris, LN, Liotcheva, V, Broadwater, G, Ramirez, MJ, Maimonis, P, Anderson, S, Everett, T, Harpole, D, Moore, MB, Berry, DA, Rizzeri, D, Vredenburgh, JJ, and Bentley, RC. "Comparison of methods of measuring HER-2 in metastatic breast cancer patients treated with high-dose chemotherapy." J Clin Oncol 19, no. 6 (March 15, 2001): 1698-1706. Full Text Link to Item
  - Harpole, DH, Moore, MB, Herndon, JE, Aloia, T, D'Amico, TA, Sporn, T, Parr, A, Linoila, I, and Allegra, C. "The prognostic value of molecular marker analysis in patients treated with trimodality therapy for esophageal cancer." Clin Cancer Res 7, no. 3 (March 2001): 562-569. Link to Item
  - Aloia, T, Bepler, G, Harpole, D, Goodman, PC, McAdams, HP, Erasmus, JJ, Herndon, JE, and Patz, EF. "Integration of peripheral blood biomarkers with computed tomography to differentiate benign from malignant pulmonary opacities." Cancer Detect Prev 25, no. 4 (2001): 336-343. Link to Item
  - Salgia, R, Harpole, D, II, JEH, Pisick, E, Elias, A, and Skarin, AT. "Role of serum tumor markers CA 125 and CEA in non-small cell lung cancer." Anticancer Research 21, no. 2 B (2001): 1241-1246.
  - Lau, CL, Harpole, DH, and Patz, E. "Staging techniques for lung cancer." Chest Surg Clin N Am 10, no. 4 (November 2000): 781-801. (Review) Link to Item
  - D'Amico, TA, and Harpole, DH. "Molecular biology of esophageal cancer." Chest Surg Clin N Am 10, no. 3 (August 2000): 451-469. (Review) Link to Item
  - Patz, EF, Rossi, S, Harpole, DH, Herndon, JE, and Goodman, PC. "Correlation of tumor size and survival in patients with stage IA non-small cell lung cancer." Chest 117, no. 6 (June 2000): 1568-1571. Link to Item
  - D'Amico, TA, Aloia, TA, Moore, MB, Herndon, JE, Brooks, KR, Lau, CL, and Harpole, DH. "Molecular biologic substaging of stage I lung cancer according to gender and histology." Ann Thorac Surg 69, no. 3 (March 2000): 882-886. Link to Item
  - Lau, CL, and Harpole, DH. "Noninvasive clinical staging modalities for lung cancer." Seminars in Surgical Oncology 18, no. 2 (March 1, 2000): 116-123. (Review) Full Text
  - Lau, CL, and Harpole, DH. "Noninvasive clinical staging modalities for lung cancer." Semin Surg Oncol 18, no. 2 (March 2000): 116-123. (Review) Link to Item
  - Kawakami, K, Brabender, J, Lord, RV, Groshen, S, Greenwald, BD, Krasna, MJ, Yin, J, Fleisher, AS, Abraham, JM, Beer, DG, Sidransky, D, Huss, HT, Demeester, TR, Eads, C, Laird, PW, Ilson, DH, Kelsen, DP, Harpole, D, Moore, M-B, Danenberg, KD, Danenberg, PV, and Meltzer, SJ. "Hypermethylated APC DNA in plasma and prognosis of patients with esophageal adenocarcinoma." Journal of the National Cancer Institute 92, no. 22 (2000): 1805-1811.
  - Espada, R, Rodarte, J, Miller, C, Barnard, C, Carter, J, Harpole, D, and et, A. "Rationale and design of the National Emphysema Treatment Trial - A prospective randomized trial of lung volume reduction surgery." Chest 116, no. 6 (December 1, 1999): 1750-1761. Full Text
  - Grichnik, KP, Ijsselmuiden, AJ, D'Amico, TA, Harpole, DH, White, WD, Blumenthal, JA, and Newman, MF. "Cognitive decline after major noncardiac operations: a preliminary prospective study." Ann Thorac Surg 68, no. 5 (November 1999): 1786-1791. Link to Item
  - Rodarte, J, Miller, C, Barnard, P, Carter, J, DuBose, K, Harpole, D, and et, A. "Rationale and design of the national emphysema treatment trial (NETT): A prospective randomized trial of lung volume reduction surgery." Edited by J Rodarte, C Miller, P Barnard, J Carter, K DuBose, and D Harpole. The Journal of Thoracic and Cardiovascular Surgery 118, no. 3 (September 1999): 518-528. Full Text
  - Rodarte, J, Miller, C, Barnard, P, Carter, J, DuBose, K, Harpole, D, and et, A. "Rationale and design of the national emphysema treatment trial (NETT): A prospective randomized trial of lung volume reduction surgery." Edited by J Rodarte, C Miller, P Barnard, J Carter, K DuBose, and D Harpole. The Journal of Thoracic and Cardiovascular Surgery 118, no. 3 (September 1999): 518-528. Full Text
  - Harpole, DH, DeCamp, MM, Daley, J, Hur, K, Oprian, CA, Henderson, WG, and Khuri, SF. "Prognostic models of thirty-day mortality and morbidity after major pulmonary resection." J Thorac Cardiovasc Surg 117, no. 5 (May 1999): 969-979. Full Text Link to Item
  - D'Amico, TA, Massey, M, Herndon, JE, Moore, MB, and Harpole, DH. "A biologic risk model for stage I lung cancer: immunohistochemical analysis of 408 patients with the use of ten molecular markers." J Thorac Cardiovasc Surg 117, no. 4 (April 1999): 736-743. Link to Item
  - Kwiatkowski, DJ, Harpole, DH, Godleski, J, Herndon, JE, Shieh, DB, Richards, W, Blanco, R, Xu, HJ, Strauss, GM, and Sugarbaker, DJ. "Molecular pathologic substaging in 244 stage I non-small-cell lung cancer patients: clinical implications." J Clin Oncol 16, no. 7 (July 1998): 2468-2477. Full Text Link to Item
  - Harpole, DH. "The evolution of therapy for patients with stage IIIA (N2) lung cancer." Chest 112, no. 4 Suppl (October 1997): 201S-202S. Link to Item
  - Clary, B, Skaryak, L, Tedder, M, Hilton, A, Botz, G, and Harpole, D. "Methemoglobinemia complicating topical anesthesia during bronchoscopic procedures." Journal of Thoracic and Cardiovascular Surgery 114, no. 2 (1997): 293-295. Full Text
  - Harpole, DH, Gall, SA, Wolfe, WG, Rankin, JS, and Jones, RH. "Effects of valve replacement on ventricular mechanics in mitral regurgitation and aortic stenosis." Ann Thorac Surg 62, no. 3 (September 1996): 756-761. Link to Item
  - Jaklitsch, MT, DeCamp, MM, Liptay, MJ, Harpole, DH, Swanson, SJ, Mentzer, SJ, and Sugarbaker, DJ. "Video-assisted thoracic surgery in the elderly. A review of 307 cases." Chest 110, no. 3 (September 1996): 751-758. Link to Item
  - Sugarbaker, DJ, Garcia, JP, Richards, WG, Harpole, DH, Healy-Baldini, E, DeCamp, MM, Mentzer, SJ, Liptay, MJ, Strauss, GM, and Swanson, SJ. "Extrapleural pneumonectomy in the multimodality therapy of malignant pleural mesothelioma. Results in 120 consecutive patients." Ann Surg 224, no. 3 (September 1996): 288-294. Link to Item
  - Harpole, DH, Healey, EA, DeCamp, MM, Mentzer, SJ, Strauss, GM, and Sugarbaker, DJ. "Chest wall invasive non-small cell lung cancer: patterns of failure and implications for a revised staging system." Ann Surg Oncol 3, no. 3 (May 1996): 261-269. Link to Item
  - Harpole, DH, Richards, WG, Herndon, JE, and Sugarbaker, DJ. "Angiogenesis and molecular biologic substaging in patients with stage I non-small cell lung cancer." Ann Thorac Surg 61, no. 5 (May 1996): 1470-1476. Full Text Link to Item
  - Harpole, DH, Liptay, MJ, DeCamp, MM, Mentzer, SJ, Swanson, SJ, and Sugarbaker, DJ. "Prospective analysis of pneumonectomy: risk factors for major morbidity and cardiac dysrhythmias." Ann Thorac Surg 61, no. 3 (March 1996): 977-982. Full Text Link to Item
  - Harpole, DH, Herndon, JE, Young, WG, Wolfe, WG, and Sabiston, DC. "Stage I nonsmall cell lung cancer. A multivariate analysis of treatment methods and patterns of recurrence." Cancer 76, no. 5 (September 1, 1995): 787-796. Link to Item
  - DeCamp, MM, Jaklitsch, MT, Mentzer, SJ, Harpole, DH, and Sugarbaker, DJ. "The safety and versatility of video-thoracoscopy: a prospective analysis of 895 consecutive cases." J Am Coll Surg 181, no. 2 (August 1995): 113-120. Link to Item
  - Harpole, DH, Marks, JR, Richards, WG, Herndon, JE, and Sugarbaker, DJ. "Localized adenocarcinoma of the lung: oncogene expression of erbB-2 and p53 in 150 patients." Clin Cancer Res 1, no. 6 (June 1995): 659-664. Link to Item
  - Harpole, DH. "Prognostic issues in non-small cell lung cancer." Chest 107, no. 6 Suppl (June 1995): 267S-269S. Link to Item
  - Mentzer, SJ, DeCamp, MM, Harpole, DH, and Sugarbaker, DJ. "Thoracoscopy and video-assisted thoracic surgery in the treatment of lung cancer." Chest 107, no. 6 Suppl (June 1995): 298S-301S. Link to Item
  - Strauss, GM, Kwiatkowski, DJ, Harpole, DH, Lynch, TJ, Skarin, AT, and Sugarbaker, DJ. "Molecular and pathologic markers in stage I non-small-cell carcinoma of the lung." J Clin Oncol 13, no. 5 (May 1995): 1265-1279. (Review) Full Text Link to Item
  - Harpole, DH, Herndon, JE, Wolfe, WG, Iglehart, JD, and Marks, JR. "A prognostic model of recurrence and death in stage I non-small cell lung cancer utilizing presentation, histopathology, and oncoprotein expression." Cancer Res 55, no. 1 (January 1, 1995): 51-56. Link to Item
  - Harpole, DH, Herndon, JE, Young, WG, Wolfe, WG, and Sabiston, DC. "Stage I nonsmall cell lung cancer. A multivariate analysis of treatment methods and patterns of recurrence." Cancer 76, no. 5 (January 1, 1995): 787-796. Full Text
  - Jaklitsch, MT, Harpole, DH, Healey, EA, and Sugarbaker, DJ. "Current Issues in the Staging of Esophageal Cancer." Semin Radiat Oncol 4, no. 3 (July 1994): 135-145. Full Text Link to Item
  - Harpole, DH, and Jones, RH. "Left ventricular function under stress before and after myocardial revascularization." Am Heart J 124, no. 2 (August 1992): 273-279. Link to Item
  - Harpole, DH, Feldman, JM, Buchanan, S, Young, WG, and Wolfe, WG. "Bronchial carcinoid tumors: a retrospective analysis of 126 patients." Ann Thorac Surg 54, no. 1 (July 1992): 50-54. Link to Item
  - Harpole, DH, Johnson, CM, Wolfe, WG, George, SL, and Seigler, HF. "Analysis of 945 cases of pulmonary metastatic melanoma." J Thorac Cardiovasc Surg 103, no. 4 (April 1992): 743-748. Link to Item
  - Harpole, DH, Davidson, CJ, Skelton, TN, Kisslo, KB, Jones, RH, and Bashore, TM. "Early and late changes in left ventricular systolic performance after percutaneous aortic balloon valvuloplasty." Am J Cardiol 66, no. 3 (August 1, 1990): 327-332. Link to Item
  - Harpole, DH, Rankin, JS, Wolfe, WG, Clements, FM, Van Trigt, P, Young, WG, and Jones, RH. "Effects of standard mitral valve replacement on left ventricular function." Ann Thorac Surg 49, no. 6 (June 1990): 866-873. Link to Item
  - Harpole, DH, Davidson, CJ, Skelton, TN, Kisslo, KB, Jones, RH, and Bashore, TM. "Changes in left ventricular systolic performance immediately after percutaneous aortic balloon valvuloplasty." Am J Cardiol 65, no. 18 (May 15, 1990): 1213-1218. Link to Item
  - Harpole, DH, and Jones, RH. "Serial assessment of ventricular performance after valve replacement for aortic stenosis." J Thorac Cardiovasc Surg 99, no. 4 (April 1990): 645-650. Link to Item
  - Clements, FM, Harpole, DH, Quill, T, Jones, RH, and McCann, RL. "Estimation of left ventricular volume and ejection fraction by two-dimensional transoesophageal echocardiography: comparison of short axis imaging and simultaneous radionuclide angiography." Br J Anaesth 64, no. 3 (March 1990): 331-336. Link to Item
  - Harpole, DH, Davidson, C, Skelton, T, Jones, RH, and Bashore, TM. "Serial evaluation of ventricular function after percutaneous aortic balloon valvuloplasty." Am Heart J 119, no. 1 (January 1990): 130-135. Link to Item
  - Harpole, DH, Rankin, JS, Wolfe, WG, Smith, LR, Young, WG, Clements, FM, and Jones, RH. "Assessment of left ventricular functional preservation during isolated cardiac valve operations." Circulation 80, no. 5 Pt 2 (November 1989): III1-III9. Link to Item
  - Harpole, DH, Skelton, TN, Davidson, CJ, Jones, RH, and Bashore, TM. "Validation of pressure-volume data obtained in patients by initial transit radionuclide angiocardiography." Am Heart J 118, no. 5 Pt 1 (November 1989): 983-989. Link to Item
  - Harpole, DH, Clements, FM, Quill, T, Wolfe, WG, Jones, RH, and McCann, RL. "Right and left ventricular performance during and after abdominal aortic aneurysm repair." Ann Surg 209, no. 3 (March 1989): 356-362. Link to Item
  - Davidson, CJ, Harpole, DA, Kisslo, K, Skelton, TN, Kisslo, J, Jones, RH, and Bashore, TM. "Analysis of the early rise in aortic transvalvular gradient after aortic valvuloplasty." Am Heart J 117, no. 2 (February 1989): 411-417. Link to Item
  - Harpole, DH, Bigelow, C, Young, WG, Wolfe, WG, and Sabiston, DC. "Alveolar cell carcinoma of the lung: a retrospective analysis of 205 patients." Ann Thorac Surg 46, no. 5 (November 1988): 502-507. Link to Item
  - Wanebo, HJ, Cooper, PH, Young, DV, Harpole, DH, and Kaiser, DL. "Prognostic factors in head and neck melanoma. Effect of lesion location." Cancer 62, no. 4 (August 15, 1988): 831-837. Link to Item
  - Wanebo, HJ, Harpole, D, and Teates, CD. "Radionuclide lymphoscintigraphy with technetium 99m antimony sulfide colloid to identify lymphatic drainage of cutaneous melanoma at ambiguous sites in the head and neck and trunk." Cancer 55, no. 6 (1985): 1403-1413.
- Other Articles
  - Burt, B, Kubasiak, , and Harpole, DH. "Value of circulating insulin-like growth factor-associated proteins for the detection of stage I non-small cell lung cancer Discussion." JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY 149, no. 3 (March 2015): 734-+. Link to Item
  - Rao, V, Kindi, A, Jr, HDH, and Rosengart, TK. "Sustained release of milrinone delivered via microparticles in a rodent model of myocardial infarction Discussion." JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY 148, no. 5 (November 2014): 2323-2324. Link to Item
  - Coles, JG, Kim, M, Mckeown, P, Harpole, DH, and Backer, CL. "Patient Genotypes Impact Survival After Surgery for Isolated Congenital Heart Disease DISCUSSION." ANNALS OF THORACIC SURGERY 98, no. 1 (July 2014): 110-111. Link to Item
  - Jr, HDH, Swanson, SJ, Ginsburg, D, Turna, A, and Jr, DMM. "Lung Volume Reduction Surgery Using the NETT Selection Criteria DISCUSSION." ANNALS OF THORACIC SURGERY 91, no. 5 (May 2011): 1561-1561. Link to Item
  - Potti, A, Mukherjee, S, Petersen, R, Dressman, HK, Bild, A, Koontz, J, Kratzke, R, Watson, MA, Kelley, M, Ginsburg, GS, West, M, Harpole, DH, and Nevins, JR. "Retraction: A genomic strategy to refine prognosis in early-stage non-small-cell lung cancer. N Engl J Med 2006;355:570-80." N Engl J Med 364, no. 12 (March 24, 2011): 1176-. Full Text Link to Item
  - Berry, MF, Atkins, Z, Tong, BC, Harpole, DH, D'Amico, TA, and Onaitis, MW. "A comprehensive evaluation for aspiration after esophagectomy reduces the incidence of postoperative pneumonia." Dysphagia 26, no. 3 (2011): 326--. Full Text
  - Potti, A, Dressman, HK, Bild, A, Riedel, RF, Chan, G, Sayer, R, Cragun, J, Cottrill, H, Kelley, MJ, Petersen, R, Harpole, D, Marks, J, Berchuck, A, Ginsburg, GS, Febbo, P, Lancaster, J, and Nevins, JR. "Retraction: Genomic signatures to guide the use of chemotherapeutics." Nat Med 17, no. 1 (January 2011): 135-. Full Text Link to Item
  - Krasna, MJ, Kim, , Harpole, DH, Schipper, PH, and Low, DE. "Pathologic T0N1 Esophageal Cancer After Neoadjuvant Therapy and Surgery: An Orphan Status DISCUSSION." ANNALS OF THORACIC SURGERY 90, no. 3 (September 2010): 890-891. Link to Item
  - Swanson, SJ, Seely, , Harpole, DH, and Block, MI. "Systematic Classification of Morbidity and Mortality After Thoracic Surgery DISCUSSION." ANNALS OF THORACIC SURGERY 90, no. 3 (September 2010): 942-942. Link to Item
  - Harpole, DH, Poullis, MP, Decamp, MM, and Murthy, SC. "Discussion." Annals of Thoracic Surgery 90, no. 2 (2010): 382--. Full Text
  - Hsu, DS, Balakumaran, BS, Acharya, CR, Vlahovic, V, Walters, KS, Garman, K, Anders, C, Riedel, RF, Lancaster, J, Harpole, D, and al, E. "Pharmacogenomic strategies provide a rational approach to the treatment of cisplatin-resistant patients with advanced cancer (Journal of Clinical Oncology (2007) 25, (4350-4357))." Journal of Clinical Oncology 28, no. 35 (2010): 5229--. Full Text
  - Krasna, MJ, Harpole, DH, Schipper, PH, and Low, DE. "Discussion." Annals of Thoracic Surgery 90, no. 3 (2010): 890-891. Full Text
  - Swanson, SJ, Harpole, DH, and Block, MI. "Discussion." Annals of Thoracic Surgery 90, no. 3 (2010): 942--. Full Text
  - Pham, D, and Harpole, DH. "Stage I NSCLC: elucidating the prognostic factors." Thorax 64, no. 3 (March 2009): 185-186. Full Text Link to Item
  - Kim, WJ, Silverman, EK, Hoffman, E, Criner, GJ, Mosenifar, Z, Sciurba, FC, Make, BJ, Carey, V, Estépar, RSJ, Diaz, A, Reilly, JJ, Martinez, FJ, Washko, GR, Fishman, AP, Bozzarello, BA, Al-Amin, A, Katz, M, Wheeler, C, Baker, E, Barnard, P, Cagle, P, Carter, J, Chatziioannou, S, Conejo-Gonzales, K, Dubose, K, Haddad, J, Hicks, D, Kleiman, N, Milburn-Barnes, M, Nguyen, C, Reardon, M, Reeves-Viets, J, Sax, S, Sharafkhaneh, A, Wilson, O, Young, C, Espada, R, Butanda, R, Ellisor, M, Fox, P, and Hale, K et al. "CT metrics of airway disease and emphysema in severe COPD." Chest 136, no. 2 (2009): 396-404. Full Text
  - Potti, A, Dressman, HK, Bild, A, Riedel, RF, Chan, G, Sayer, R, Cragun, J, Cottrill, H, Kelley, MJ, Petersen, R, Harpole, D, Marks, J, Berchuck, A, Ginsburg, GS, Febbo, P, Lancaster, J, and Nevins, JR. "Corrigendum: Genomic signatures to guide the use of chemotherapeutics (Nature Medicine (2006) 12, (1294-1300))." Nature Medicine 14, no. 8 (2008): 889--. Full Text
  - Reed, CE, Harpole, DH, Posther, KE, Woolson, SL, Downey, RJ, and Meyers, BR. "Results of ACOSOG Z0050 trial: The utility of FDG-PET in staging potentially operable non-small cell lung cancer (vol 126, pg 1943, 2003)." JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY 133, no. 4 (April 2007): 864-864. Link to Item
  - Potti, A, Jr, HDH, and Nevins, JR. "Refining prognosis in non-small-cell lung cancer - Reply." NEW ENGLAND JOURNAL OF MEDICINE 356, no. 2 (January 11, 2007): 190-191. Link to Item
  - Potti, A, Dressman, HK, Bild, A, Riedel, RF, Chan, G, Sayer, R, Cragun, J, Cottrill, H, Kelley, MJ, Petersen, R, Harpole, D, Marks, J, Berchuck, A, Ginsburg, GS, Febbo, P, Lancaster, J, and Nevins, JR. "Erratum: Genomic signatures to guide the use of chemotherapeutics (Nature (2006) 12, (1294-1300))." Nature Medicine 13, no. 11 (2007): 1388--. Full Text
  - Potti, A, Dressman, HK, Bild, A, Riedel, RF, Chan, G, Sayer, R, Cragun, J, Cottrill, H, Kelley, MJ, Petersen, R, Harpole, D, Marks, J, Berchuck, A, Ginsburg, GS, Febbo, P, Lancaster, J, and Nevins, JR. "Genomic signatures to guide the use of chemotherapeutics." Nat Med 12, no. 11 (November 2006): 1294-1300. Full Text Link to Item
  - Rice, DC, Erasmus, JJ, Stevens, CW, Vaporciyan, AA, Wu, JS, Tsao, AS, Walsh, GL, Swisher, SG, Hofstetter, WL, Ordonez, NG, Smythe, WR, D'Amico, TA, Krasna, MJ, Nichols, FC, and Jr, DHH. "Extended surgical staging for potentially resectable malignant pleural mesothelioma." Annals of Thoracic Surgery 80, no. 6 (2005): 1988-1993. Full Text
  - Nguyen, DM, Chen, GA, Reddy, R, Tsai, W, Schrump, WD, Jr, GC, Schrump, DS, Jones, DA, Mentzer, SJ, and Jr, DHH. "Potentiation of paclitaxel cytotoxicity in lung and esophageal cancer cells by pharmacologic inhibition of the phosphoinositide 3-kinase/protein kinase B (Akt)-mediated signaling pathway." Journal of Thoracic and Cardiovascular Surgery 127, no. 2 (2004): 365-375. Full Text
  - Vaporciyan, AA, Correa, AM, Rice, DC, Roth, JA, Smythe, WR, Swisher, SG, Walsh, GL, Jr, JBP, Downey, RJ, Miller, DL, and Jr, DHH. "Risk factors associated with atrial fibrillation after noncardiac thoracic surgery: Analysis of 2588 patients." Journal of Thoracic and Cardiovascular Surgery 127, no. 3 (2004): 779-786. Full Text
  - Mackensen, GB, Ti, LK, Phillips-Bute, BG, Mathew, JP, Newman, MF, Grocott, HP, and Neurologic Outcome Research Group (NORG), . "Cerebral embolization during cardiac surgery: impact of aortic atheroma burden." Br J Anaesth 91, no. 5 (November 2003): 656-661. Link to Item
  - Petre, PM, Jr, FAB, Tigan, S, Spears, JR, Patterson, GA, Swisher, SG, Jr, DHH, and Goldstraw, P. "Hyperbaric oxygen as a chemotherapy adjuvant in the treatment of metastatic lung tumors in a rat model." Journal of Thoracic and Cardiovascular Surgery 125, no. 1 (2003): 85-95. Full Text
  - Swaminathan, M, McCreath, BJ, Phillips-Bute, BG, Newman, MF, Mathew, JP, Smith, PK, Blumenthal, JA, Stafford-Smith, M, and Perioperative Outcomes Research Group, . "Serum creatinine patterns in coronary bypass surgery patients with and without postoperative cognitive dysfunction." Anesth Analg 95, no. 1 (July 2002): 1-8. Link to Item
  - Grigore, AM, Grocott, HP, Mathew, JP, Phillips-Bute, B, Stanley, TO, Butler, A, Landolfo, KP, Reves, JG, Blumenthal, JA, Newman, MF, and Neurologic Outcome Research Group of the Duke Heart Center, . "The rewarming rate and increased peak temperature alter neurocognitive outcome after cardiac surgery." Anesth Analg 94, no. 1 (January 2002): 4-10. Link to Item
  - Harpole, DH. "Expression of human telomerase subunit genes in primary lung cancer and its clinical significance - Invited commentary." ANNALS OF THORACIC SURGERY 70, no. 2 (August 2000): 405-406. Full Text Link to Item
  - Kwiatkowski, DJ, Jr, DHH, Godlewski, J, II, JEH, Shieh, D-B, Richards, W, Blanco, R, Xu, H-J, Strauss, GM, and Sugarbaker, DJ. "Molecular pathologic substaging in 244 stage I non-small-cell lung cancer patients: Clinical implications." Pneumologie 53, no. 2 (1999): 105--.
  - Harpole, DH. "Prognostic significance of HER-2/neu overexpression in stage I adenocarcinoma of lung." ANNALS OF THORACIC SURGERY 66, no. 4 (October 1998): 1163-1164. Link to Item
  - Miller, DL, Harpole, DH, and Pass, HI. "Angiogenesis and molecular biologic substaging in patients with stage I non-small cell lung cancer - Discussion." ANNALS OF THORACIC SURGERY 61, no. 5 (May 1996): 1476-1476. Link to Item

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.

Education, Training, & Certifications

Duke Appointment History

Selected Grants

Selected Publications

Book Sections

Conference Papers

Journal Articles

Other Articles