Overview
Notable features of my work are: (1) reliance on analytic strategies such as meta-analysis, simulation, decision analysis and cost-effectiveness analysis; (2) a balancing of methodological rigor the needs of medical professionals; and (3) dependence on interdisciplinary groups of experts.
This approach is best illustrated by the Stroke Prevention Patient Outcome Research Team (PORT), for which I served as principal investigator. Funded by the AHCPR, the PORT involved 35 investigators at 13 institutions. The Stroke PORT has been highly productive and has led to a stroke prevention project funded as a public/private partnership by the AHCPR and DuPont Pharma, the Managing Anticoagulation Services Trial (MAST). MAST is a practice improvement trial in 6 managed care organizations, focussing on optimizing anticoagulation for individuals with atrial fibrillation.
I serve as consultant in the general area of analytic strategies for clinical policy development, as well as for specific projects related to stroke (e.g., acute stroke treatment, management of atrial fibrillation, and use of carotid endarterectomy.) I have worked with AHCPR (now AHRQ), ACP, AHA, AAN, Robert Wood Johnson Foundation, NSA, WHO, and several pharmaceutical companies.
Key Words: clinical policy, disease management, stroke, decision analysis, clinical guidelines
Current Appointments & Affiliations
Professor Emeritus of Medicine
·
2026 - Present
Medicine, General Internal Medicine,
Medicine
Director of the Center for Clinical Health Policy Research
·
1988 - Present
Institutes and Centers,
School of Medicine
Professor of Pathology
·
2009 - Present
Pathology,
Clinical Science Departments
Affiliate, Duke Global Health Institute
·
2009 - Present
Duke Global Health Institute,
University Institutes and Centers
Recent Publications
Walking in the Free World: Establishing Normative Trajectories for Ecological Assessment of Robust Gait Variability with Age
Preprint · March 6, 2026 Full text Cite3598 Resilience mediates the relationship between baseline health and functional recovery in older patients following hip fracture
Conference Age and Ageing · February 5, 2026 AbstractIntroductionHip fractures in older adults often lead to prolonged disability and reduced quality of life. While baselin ... Full text CiteImplications of Primary Care Scenarios for the ‘Performance’ of Chronic Care Delivery in Switzerland: A Systems Modelling View
Journal Article Systems Research and Behavioral Science · January 1, 2026 Switzerland and most high-income countries are confronted with a growing number of people with chronic conditions who must be treated by healthcare systems that are designed to provide acute care predominantly. A widely supported solution is strengthening ... Full text CiteRecent Grants
Expanding Quality Care for Glaucoma through a Provider-Patient Partnership
ResearchCo Investigator · Awarded by National Institutes of Health · 2007 - 2013Thrombosis and Hemostasis Centers Research and Prevention Network
ResearchConsultant · Awarded by Centers for Disease Control and Prevention · 2002 - 2013EPC Project: Medical Test Guides - training modules
ResearchCo Investigator · Awarded by Agency for Healthcare Research and Quality · 2011 - 2012View All Grants
Education
University of Maryland, College Park ·
1980
M.D.