Overview
Notable features of my work are: (1) reliance on analytic strategies such as meta-analysis, simulation, decision analysis and cost-effectiveness analysis; (2) a balancing of methodological rigor the needs of medical professionals; and (3) dependence on interdisciplinary groups of experts.
This approach is best illustrated by the Stroke Prevention Patient Outcome Research Team (PORT), for which I served as principal investigator. Funded by the AHCPR, the PORT involved 35 investigators at 13 institutions. The Stroke PORT has been highly productive and has led to a stroke prevention project funded as a public/private partnership by the AHCPR and DuPont Pharma, the Managing Anticoagulation Services Trial (MAST). MAST is a practice improvement trial in 6 managed care organizations, focussing on optimizing anticoagulation for individuals with atrial fibrillation.
I serve as consultant in the general area of analytic strategies for clinical policy development, as well as for specific projects related to stroke (e.g., acute stroke treatment, management of atrial fibrillation, and use of carotid endarterectomy.) I have worked with AHCPR (now AHRQ), ACP, AHA, AAN, Robert Wood Johnson Foundation, NSA, WHO, and several pharmaceutical companies.
Key Words: clinical policy, disease management, stroke, decision analysis, clinical guidelines
Current Appointments & Affiliations
Professor Emeritus of Medicine
·
2026 - Present
Medicine, General Internal Medicine,
Medicine
Director of the Center for Clinical Health Policy Research
·
1988 - Present
Institutes and Centers,
School of Medicine
Professor of Pathology
·
2009 - Present
Pathology,
Clinical Science Departments
Affiliate, Duke Global Health Institute
·
2009 - Present
Duke Global Health Institute,
University Institutes and Centers
Recent Publications
Association between weather, air quality and asthma-related emergency department visits: a retrospective time-series study in Singapore.
Journal Article BMJ Open · December 18, 2025 OBJECTIVES: To evaluate the association between asthma-related emergency department (ED) visits and weather, air quality, monsoons, haze and cultural festivals in Singapore. DESIGN: Retrospective cohort study. SETTING: A public healthcare cluster that cove ... Full text Link to item CiteA Tailored, Multi-Component Falls Prevention Intervention for Community-Dwelling Older Adults in Singapore
Conference Innovation in Aging · December 1, 2025 AbstractDespite strong evidence supporting personalized, multi-component falls prevention programs, many existing programs in Singapore focus primarily on exercise and lack individualization. This study a ... Full text CiteFalls and Falls Prevention in Singapore: Policy Insights From a Dynamic Simulation Model
Conference Innovation in Aging · December 1, 2025 AbstractFalls among older adults have complex etiologies, requiring a multi-system approach for effective prevention. In Singapore, 85% of geriatric trauma cases presented in the emergency department resu ... Full text CiteRecent Grants
Expanding Quality Care for Glaucoma through a Provider-Patient Partnership
ResearchCo Investigator · Awarded by National Institutes of Health · 2007 - 2013Thrombosis and Hemostasis Centers Research and Prevention Network
ResearchConsultant · Awarded by Centers for Disease Control and Prevention · 2002 - 2013EPC Project: Medical Test Guides - training modules
ResearchCo Investigator · Awarded by Agency for Healthcare Research and Quality · 2011 - 2012View All Grants
Education, Training & Certifications
University of Maryland, College Park ·
1980
M.D.