The Sherwood lab is interested in understanding mechanisms that drive dynamic cellular behaviors underlying normal development and human disease. We study 1) How cells invade into tissues, 2) How stem cells interact with their niches, and 3) How cells control and interact with extracellular matrix. Our lab primarily examines C. elegans development, in which simple cellular complexity, amenability to genetics/genomics/transgenics/molecular perturbations, and evolutionary comparisons facilitates powerful insights. One particular emphasis of our work is live-cell imaging, where we watch cellular behaviors and cell-extracellular matrix interactions unfold in real-time to understand their regulation and function. Cell invasion, stem cell regulation, and cell-matrix interactions are fundamental to development, regeneration, cancer, and aging. Our work aims to advance our understanding of these fascinating processes and positively influence human health.
Current Appointments & Affiliations
Jerry G. and Patricia Crawford Hubbard Professor · 2019 - Present Biology, Trinity College of Arts & Sciences
Associate Chair of the Department of Biology · 2023 - Present Biology, Trinity College of Arts & Sciences
Education, Training & Certifications
Duke University · 1997 Ph.D.
Wesleyan University · 1990 B.A.