David Timothy H. Tanaka
Professor of Pediatrics
Past research interests focused on the development of neurokinin-mediated airway neuromodulation. Present research has focused on improving resident education, clinical operations, and health sciences finance.
Current research in resident education involves the acquisition of resident skills. Present projects explore the acqiusition of intubation skills as well as the potential for computer simulation and visual depiction of the human airway to spped the learning process.
Current research into clinical operations includes the use of clinical databases to improve patient safety and care. A major effort is presently underway to understand and identify key components associated with GI inflammation in the neonate.
Current administrative research interests includes revenue analysis for the division and hospital as well as management engineering analysis for bed utilization. Accomplishments to date include elimination of $2 million debt in ICN, initiation of PDC pilot project and acceptance of modelling approach with hospital management engineering; identification and allocatuion of medicaid supplemental payments (est. $4-5 million). Recent work in the general area of professional charge capture, effects of light pollution in the ICN, and use of biophotonics in the clinical setting.
Current research in resident education involves the acquisition of resident skills. Present projects explore the acqiusition of intubation skills as well as the potential for computer simulation and visual depiction of the human airway to spped the learning process.
Current research into clinical operations includes the use of clinical databases to improve patient safety and care. A major effort is presently underway to understand and identify key components associated with GI inflammation in the neonate.
Current administrative research interests includes revenue analysis for the division and hospital as well as management engineering analysis for bed utilization. Accomplishments to date include elimination of $2 million debt in ICN, initiation of PDC pilot project and acceptance of modelling approach with hospital management engineering; identification and allocatuion of medicaid supplemental payments (est. $4-5 million). Recent work in the general area of professional charge capture, effects of light pollution in the ICN, and use of biophotonics in the clinical setting.
Current Appointments & Affiliations
- Professor of Pediatrics, Pediatrics, Neonatology, Pediatrics 2021
Contact Information
- 2424 Erwin Road, Hock Plaza Suite 504, Durham, NC 27710
- Box 3179 Med Ctr, Durham, NC 27710
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david.tanaka@duke.edu
(919) 681-6033
- Background
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Education, Training, & Certifications
- M.D., Johns Hopkins University 1979
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Previous Appointments & Affiliations
- Professor of Pediatrics, Pediatrics, Neonatology, Pediatrics 2006 - 2020
- Clinical Professor of Pediatrics, Pediatrics, Neonatology, Pediatrics 2003 - 2006
- Associate Clinical Professor of Pediatrics, Pediatrics, Neonatology, Pediatrics 1996 - 2003
- Acting Chief, Division of Neonatology, Pediatrics, Neonatology, Pediatrics 1993 - 1996
- Associate Professor of Pediatrics, Pediatrics, Neonatology, Pediatrics 1994 - 1996
- Assistant Professor of Pediatrics, Pediatrics, Neonatology, Pediatrics 1987 - 1994
- Recognition
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Awards & Honors
- Use of Technology: Analytics. NC Technology Association. November 2017
- Expertise
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Subject Headings
- Research
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Selected Grants
- Multidisciplinary Neonatal Training Grant awarded by National Institutes of Health 2010 - 2015
- Temperature & Vasomotor Tone During the First 5 Days in Preterms Less than 1000g awarded by National Institutes of Health 2010 - 2013
- Maturation Of Neurokinin Reactivity In Airways awarded by National Institutes of Health 1994
- Maturation Of Neurokinin Reactivity In Rabbit Airways awarded by National Institutes of Health 1991 - 1994
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Puia-Dumitrescu, Mihai, Laura N. Sullivan, David Tanaka, Kimberley Fisher, Rick Pittman, Karan R. Kumar, William F. Malcolm, et al. “Survival, Morbidities, and Developmental Outcomes among Low Birth Weight Infants with Congenital Heart Defects.” Am J Perinatol 38, no. 13 (November 2021): 1366–72. https://doi.org/10.1055/s-0040-1712964.Full Text Link to Item
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Gray, Keyaria D., Emily A. Hannon, Elizabeth Erickson, Ariana B. Stewart, Charles T. Wood, Kimberley Fisher, Sophie K. Shaikh, and David Tanaka. “Influence of Early Lactation Assistance on Inpatient Exclusive Breastfeeding Rates.” J Hum Lact 37, no. 3 (August 2021): 556–65. https://doi.org/10.1177/0890334420957967.Full Text Link to Item
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Dias, Patricia L., Rachel G. Greenberg, Ronald N. Goldberg, Kimberley Fisher, and David T. Tanaka. “Augmented Reality-Assisted Video Laryngoscopy and Simulated Neonatal Intubations: A Pilot Study.” Pediatrics 147, no. 3 (March 2021). https://doi.org/10.1542/peds.2020-005009.Full Text Link to Item
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Puia-Dumitrescu, Mihai, David T. Tanaka, Tracy G. Spears, Cecil J. Daniel, Karan R. Kumar, Kamlesh Athavale, Sandra E. Juul, and P Brian Smith. “Patterns of phlebotomy blood loss and transfusions in extremely low birth weight infants.” J Perinatol 39, no. 12 (December 2019): 1670–75. https://doi.org/10.1038/s41372-019-0515-6.Full Text Link to Item
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Blake, Stephanie McCallum, David Tanaka, Lisa M. Bendz, Suzanne Staebler, and Debra Brandon. “Evaluation of the Financial and Health Burden of Infants at Risk for Respiratory Syncytial Virus.” Adv Neonatal Care 17, no. 4 (August 2017): 292–98. https://doi.org/10.1097/ANC.0000000000000367.Full Text Link to Item
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DeRienzo, Christopher M., Ryan J. Shaw, Phillip Meanor, Emily Lada, Jeffrey Ferranti, and David Tanaka. “A discrete event simulation tool to support and predict hospital and clinic staffing.” Health Informatics J 23, no. 2 (June 2017): 124–33. https://doi.org/10.1177/1460458216628314.Full Text Link to Item
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Knobel-Dail, Robin B., David T. Tanaka, Diane Holditch-Davis, and John White. “Perfusion Index in Very Low Birth Weight Premature Infants During Their First 2 Weeks of Life.” Biol Res Nurs 19, no. 1 (January 2017): 45–52. https://doi.org/10.1177/1099800416656914.Full Text Link to Item
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Knobel-Dail, Robin B., Richard Sloane, Diane Holditch-Davis, and David T. Tanaka. “Negative Temperature Differential in Preterm Infants Less Than 29 Weeks Gestational Age: Associations With Infection and Maternal Smoking.” Nurs Res 66, no. 6 (2017): 442–53. https://doi.org/10.1097/NNR.0000000000000250.Full Text Link to Item
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DeRienzo, C., J. A. Kohler, E. Lada, P. Meanor, and D. Tanaka. “Demonstrating the relationships of length of stay, cost and clinical outcomes in a simulated NICU.” J Perinatol 36, no. 12 (December 2016): 1128–31. https://doi.org/10.1038/jp.2016.128.Full Text Link to Item
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Neill, Sara, Sarah Haithcock, P Brian Smith, Ronald Goldberg, Margarita Bidegain, David Tanaka, Charlene Carriker, and Jessica E. Ericson. “Sustained Reduction in Bloodstream Infections in Infants at a Large Tertiary Care Neonatal Intensive Care Unit.” Adv Neonatal Care 16, no. 1 (February 2016): 52–59. https://doi.org/10.1097/ANC.0000000000000164.Full Text Link to Item
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Kohler, J. A., R. N. Goldberg, and D. T. Tanaka. “Medicaid policy changes and its detrimental effects on neonatal reimbursement and care.” Journal of Health Care Finance 42, no. 2 (September 1, 2015).
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DeMeo, Stephen D., Lakshmi Katakam, Ronald N. Goldberg, and David Tanaka. “Predicting neonatal intubation competency in trainees.” Pediatrics 135, no. 5 (May 2015): e1229–36. https://doi.org/10.1542/peds.2014-3700.Full Text Link to Item
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Rattray, B. N., D. M. Kraus, L. R. Drinker, R. N. Goldberg, D. T. Tanaka, and C. M. Cotten. “Antenatal magnesium sulfate and spontaneous intestinal perforation in infants less than 25 weeks gestation: Editorial comment.” Obstetrical and Gynecological Survey 70, no. 3 (March 15, 2015): 160–62. https://doi.org/10.1097/01.ogx.0000462913.79440.bc.Full Text
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Rattray, B. N., D. M. Kraus, L. R. Drinker, R. N. Goldberg, D. T. Tanaka, and C. M. Cotten. “Antenatal magnesium sulfate and spontaneous intestinal perforation in infants less than 25 weeks gestation.” J Perinatol 34, no. 11 (November 2014): 819–22. https://doi.org/10.1038/jp.2014.106.Full Text Link to Item
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Seigel, Jonathan K., David T. Tanaka, Ronald N. Goldberg, P Brian Smith, C Michael Cotten, and Margarita Bidegain. “Economic impact of human milk on medical charges of extremely low birth weight infants.” Breastfeed Med 9, no. 4 (May 2014): 233–34. https://doi.org/10.1089/bfm.2013.0059.Full Text Link to Item
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Derienzo, Chris, P Brian Smith, David Tanaka, Nicholas Bandarenko, Mary Lee Campbell, Annadele Herman, Ronald N. Goldberg, and C Michael Cotten. “Feeding practices and other risk factors for developing transfusion-associated necrotizing enterocolitis.” Early Hum Dev 90, no. 5 (May 2014): 237–40. https://doi.org/10.1016/j.earlhumdev.2014.02.003.Full Text Link to Item
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Carter, B. M., D. Holditch-Davis, D. Tanaka, and T. A. Schwartz. “The relationship between black race, maternal infection and NEC in the preterm infant.” Newborn and Infant Nursing Reviews 13, no. 4 (December 1, 2013): 166–70. https://doi.org/10.1053/j.nainr.2013.09.002.Full Text
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Carter, Brigit Maria, Diane Holditch-Davis, David Tanaka, and Todd A. Schwartz. “Relationship of neonatal treatments with the development of necrotizing enterocolitis in preterm infants.” Nurs Res 61, no. 2 (2012): 96–102. https://doi.org/10.1097/NNR.0b013e3182410d33.Full Text Link to Item
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Rice, H. E., C. L. Hollingsworth, E. Bradsher, M. E. Danko, S. M. Crosby, R. N. Goldberg, D. T. Tanaka, and R. B. Knobel. “Infrared thermal imaging (thermography) of the abdomen in extremely low birthweight infants.” Journal of Surgical Radiology 1, no. 2 (October 2010): 82–89.Link to Item
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Ferranti, Jeffrey M., Matthew K. Langman, David Tanaka, Jonathan McCall, and Asif Ahmad. “Bridging the gap: leveraging business intelligence tools in support of patient safety and financial effectiveness.” J Am Med Inform Assoc 17, no. 2 (March 2010): 136–43. https://doi.org/10.1136/jamia.2009.002220.Full Text Link to Item
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Schultz, Eric D., David T. Tanaka, Ronald N. Goldberg, Daniel K. Benjamin, and P Brian Smith. “Effect of methicillin-resistant Staphylococcus aureus colonization in the neonatal intensive care unit on total hospital cost.” Infect Control Hosp Epidemiol 30, no. 4 (April 2009): 383–85. https://doi.org/10.1086/596610.Full Text Link to Item
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McDonald, Jay R., Charlene M. Carriker, Brian C. Pien, Jane V. Trinh, John J. Engemann, Lizzie J. Harrell, Mary A. Oden, et al. “Methicillin-resistant Staphylococcus aureus outbreak in an intensive care nursery: potential for interinstitutional spread.” Pediatr Infect Dis J 26, no. 8 (August 2007): 678–83. https://doi.org/10.1097/INF.0b013e3180616ce4.Full Text Link to Item
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Auten, R. L., S. N. Mason, D. T. Tanaka, K. Welty-Wolf, and M. H. Whorton. “Anti-neutrophil chemokine preserves alveolar development in hyperoxia-exposed newborn rats.” Am J Physiol Lung Cell Mol Physiol 281, no. 2 (August 2001): L336–44. https://doi.org/10.1152/ajplung.2001.281.2.L336.Full Text Link to Item
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Moya, M. P., R. H. Clark, J. Nicks, and D. T. Tanaka. “The effects of bedside blood gas monitoring on blood loss and ventilator management.” Biol Neonate 80, no. 4 (2001): 257–61. https://doi.org/10.1159/000047153.Full Text Link to Item
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Kazem, E., C. John, and D. T. Tanaka. “Neurokinin subtype receptors mediating substance P contraction in immature rabbit airways.” Pediatr Res 39, no. 1 (January 1996): 120–26. https://doi.org/10.1203/00006450-199601000-00018.Full Text Link to Item
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Badgett, R., and P. Tanaka. “The diagnostic value of the forced expiratory time.” Jama 271, no. 1 (January 5, 1994): 25. https://doi.org/10.1001/jama.271.1.25b.Full Text Link to Item
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John, C., S. Brunner, and D. T. Tanaka. “Neuromodulation mediated by neurokinin-1 subtype receptors in adult rabbit airways.” Am J Physiol 265, no. 3 Pt 1 (September 1993): L228–33. https://doi.org/10.1152/ajplung.1993.265.3.L228.Full Text Link to Item
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Scott, J. Y., S. L. Brunner, and D. T. Tanaka. “The effect of chlorothiazide on neurally mediated contraction of rabbit bronchial smooth muscle.” Am Rev Respir Dis 145, no. 1 (January 1992): 75–79. https://doi.org/10.1164/ajrccm/145.1.75.Full Text Link to Item
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Tanaka, D. T., R. E. Ando, G. L. Larsen, and C. G. Irvin. “Cholinergic mechanisms involved with histamine hyperreactivity in immune rabbit airways challenged with ragweed antigen.” Am Rev Respir Dis 144, no. 1 (July 1991): 70–75. https://doi.org/10.1164/ajrccm/144.1.70.Full Text Link to Item
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Bethel, R. A., D. T. Tanaka, L. S. Mitchell, S. P. Curtis, A. R. Leff, and C. G. Irvin. “Effect of cooling on the responsiveness of canine tracheal muscle.” Am Rev Respir Dis 142, no. 6 Pt 1 (December 1990): 1402–6. https://doi.org/10.1164/ajrccm/142.6_Pt_1.1402.Full Text Link to Item
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Tanaka, D. T., and M. M. Grunstein. “Maturation of neuromodulatory effect of substance P in rabbit airways.” J Clin Invest 85, no. 2 (February 1990): 345–50. https://doi.org/10.1172/JCI114444.Full Text Link to Item
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Cook, J. A., S. L. Brunner, and D. T. Tanaka. “Neurokinin receptors mediating substance P-induced contraction in adult rabbit airways.” Am J Physiol 258, no. 2 Pt 1 (February 1990): L99-106. https://doi.org/10.1152/ajplung.1990.258.2.L99.Full Text Link to Item
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Bratton, D. L., D. T. Tanaka, and M. M. Grunstein. “Effects of temperature on cholinergic contractility of rabbit airway muscle.” J Appl Physiol (1985) 63, no. 5 (November 1987): 1933–41. https://doi.org/10.1152/jappl.1987.63.5.1933.Full Text Link to Item
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Tanaka, D. T., and M. M. Grunstein. “Effect of substance P on neurally mediated contraction of rabbit airway smooth muscle.” J Appl Physiol (1985) 60, no. 2 (February 1986): 458–63. https://doi.org/10.1152/jappl.1986.60.2.458.Full Text Link to Item
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Grunstein, M. M., and D. T. Tanaka. “Ontogeny of respiratory control and pulmonary mechanics in newborn rabbits.” J Appl Physiol (1985) 59, no. 5 (November 1985): 1477–86. https://doi.org/10.1152/jappl.1985.59.5.1477.Full Text Link to Item
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Worthen, G. S., R. S. Gumbay, D. T. Tanaka, and M. M. Grunstein. “Opposing hemodynamic effects of substance P on pulmonary vasculature in rabbits.” J Appl Physiol (1985) 59, no. 4 (October 1985): 1098–1103. https://doi.org/10.1152/jappl.1985.59.4.1098.Full Text Link to Item
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Tanaka, D. T., and M. M. Grunstein. “Vasoactive effects of substance P on isolated rabbit pulmonary artery.” J Appl Physiol (1985) 58, no. 4 (April 1985): 1291–97. https://doi.org/10.1152/jappl.1985.58.4.1291.Full Text Link to Item
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Tanaka, D. T., and M. M. Grunstein. “Mechanisms of substance P-induced contraction of rabbit airway smooth muscle.” J Appl Physiol Respir Environ Exerc Physiol 57, no. 5 (November 1984): 1551–57. https://doi.org/10.1152/jappl.1984.57.5.1551.Full Text Link to Item
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Grunstein, M. M., D. T. Tanaka, and J. S. Grunstein. “Mechanism of substance P-induced bronchoconstriction in maturing rabbit.” J Appl Physiol Respir Environ Exerc Physiol 57, no. 4 (October 1984): 1238–46. https://doi.org/10.1152/jappl.1984.57.4.1238.Full Text Link to Item
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Conference Papers
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Qian, M., J. Nicholson, D. Tanaka, P. Dias, E. Wang, and L. Qiu. “Augmented Reality (AR) Assisted Laryngoscopy for Endotracheal Intubation Training.” In Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), 11575 LNCS:355–71, 2019. https://doi.org/10.1007/978-3-030-21565-1_24.Full Text
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