Current Appointments & Affiliations
Professor of Medicine
·
2024 - Present
Medicine, Cardiology,
Medicine
Member of the Center for Applied Genomics & Precision Medicine
·
2010 - Present
Duke Clinical Research Institute,
Institutes and Centers
Executive Team Member of Duke Center for Applied Genomics and Precision Medicine
·
2014 - Present
The Precision Medicine Program,
Medicine
Recent Publications
Can Pharmacogenetics Be Used to Predict the Response to Fesoterodine Fumarate?
Journal Article Urogynecology (Phila) · January 1, 2026 IMPORTANCE: Pharmacogenetics could address the challenge of predicting an individual's response to anticholinergic medications for urgency urinary incontinence (UUI). OBJECTIVES: Our objectives were to evaluate whether the metabolizer status of cytochrome ... Full text Link to item CiteA platelet transcriptomic signature of thromboinflammation predicts cardiovascular risk.
Journal Article JCI Insight · December 22, 2025 BACKGROUNDPlatelets are increasingly recognized as active participants in immune signaling and systemic inflammation. Upon activation, platelets form monocyte platelet aggregates (MPA) representing the crossroads of thrombosis and inflammation. We hypothes ... Full text Link to item CiteAn Update to the Clinical Pharmacogenetics Implementation Consortium (CPIC) SLCO1B1 Allele Functionality Table Leveraging Evidence from Participants of Predominantly Sub-Saharan African Ancestry.
Journal Article Clin Pharmacol Ther · December 1, 2025 The Clinical Pharmacogenetics Implementation Consortium (CPIC) has formally updated the SLCO1B1 allele functionality table based on new evidence. Notably, the alleles studied (SLCO1B1 *9, *31, *41) are enriched in the genomes of patients historically exclu ... Full text Link to item CiteRecent Grants
The VA Genomic Learning Health System: Implementing genomic medicine across diverse Veteran communities.
ResearchPrincipal Investigator · Awarded by Boston VA Research Institute, Inc. · 2024 - 2029Molecular predictors of cardiovascular events and resilience in chronic coronary artery disease
ResearchPrincipal Investigator · Awarded by NYU Langone Medical Center · 2023 - 2028Hematology & Transfusion Medicine (T32)
Inst. Training Prgm or CMEPreceptor · Awarded by National Heart, Lung, and Blood Institute · 1975 - 2026View All Grants
Education, Training & Certifications
Northwestern University ·
2002
M.D.