Current Appointments & Affiliations
Professor of Medicine
·
2024 - Present
Medicine, Cardiology,
Medicine
Member of the Center for Applied Genomics & Precision Medicine
·
2010 - Present
Duke Clinical Research Institute,
Institutes and Centers
Executive Team Member of Duke Center for Applied Genomics and Precision Medicine
·
2014 - Present
The Precision Medicine Program,
Medicine
Recent Publications
Trends in and predictors of patient pharmacogenomic test uptake in a national health care system.
Journal Article Genet Med · March 2025 PURPOSE: Better understanding patient uptake of pharmacogenomic (PGx) testing may inform its implementation and maximize the benefits that such testing can confer. This study examined patient and provider factors associated with PGx test ordering in a nati ... Full text Link to item CiteCan Pharmacogenetics Be Used to Predict the Response to Fesoterodine Fumarate?
Journal Article Urogynecology (Phila) · February 14, 2025 IMPORTANCE: Pharmacogenetics could address the challenge of predicting an individual's response to anticholinergic medications for urgency urinary incontinence (UUI). OBJECTIVES: Our objectives were to evaluate whether the metabolizer status of cytochrome ... Full text Link to item CiteThe impact of imprecise case definitions in electronic health record research: a melanoma case-study from the Million Veteran Program.
Journal Article Arch Dermatol Res · January 24, 2025 Cases for a disease can be defined broadly using diagnostic codes, or narrowly using gold-standard confirmation that often is not available in large administrative datasets. These different definitions can have significant impacts on the results and conclu ... Full text Link to item CiteRecent Grants
The VA Genomic Learning Health System: Implementing genomic medicine across diverse Veteran communities.
ResearchPrincipal Investigator · Awarded by Boston VA Research Institute, Inc. · 2024 - 2029Molecular predictors of cardiovascular events and resilience in chronic coronary artery disease
ResearchPrincipal Investigator · Awarded by NYU Langone Medical Center · 2023 - 2028Hematology & Transfusion Medicine (T32)
Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 1975 - 2026View All Grants
Education, Training & Certifications
Northwestern University ·
2002
M.D.