Deepak Voora | Scholars@Duke

Deepak Voora
Associate Professor of Medicine

Current Appointments & Affiliations

Associate Professor of Medicine, Medicine, Cardiology, Medicine 2021
Member of the Center for Applied Genomics & Precision Medicine, Duke Clinical Research Institute, Institutes and Centers 2010
Executive Team Member of Duke Center for Applied Genomics and Precision Medicine, Duke Center for Applied Genomics and Precision Medicine, Medicine 2014

Contact Information

101 Science Dr, 2187 Ciemas, Campus Box 3382, Durham, NC 27708
Duke Box 3382, Durham, NC 27710
deepak.voora@duke.edu (919) 684-6266

Background
Education, Training, & Certifications
- Fellowship, Cardiovascular Disease, Duke University School of Medicine 2006 - 2010
- Chief Resident, Internal Medicine, Washington University School of Medicine 2005 - 2006
- Resident, Internal Medicine, Washington University School of Medicine 2003 - 2005
- Intern, Internal Medicine, Washington University School of Medicine 2002 - 2003
- M.D., Northwestern University 2002
Previous Appointments & Affiliations
- Associate Professor of Medicine, Medicine, Cardiology, Medicine 2017 - 2021
- Assistant Professor of Medicine, Medicine, Cardiology, Medicine 2013 - 2017
- Medical Instructor in the Department of Medicine, Medicine, Cardiology, Medicine 2010 - 2013
- Instructor Temporary in the Department of Medicine, Medicine, Cardiology, Medicine 2010
Recognition
In the News
- MAR 30, 2022 Duke Center for Applied Genomics & Precision Medicine
  
  Providing the Best Prescription Drug Care for Veterans
- SEP 7, 2016
  
  Researchers Find Molecular Link Behind Aspirins Protective Powers
- MAR 16, 2016
  
  New Collaborative Seed Grant Program Gives Eight Awards
- MAR 16, 2016 Duke Today
  
  New Collaborative Seed Grant Program Gives Eight Awards
- JUL 8, 2013 NPR
  
  Genes may reveal when aspirin won't reduce heart risk
- JUL 8, 2013 NPR
  
  Genes may reveal when aspirin won't reduce heart risk
- JUL 7, 2013
  
  Is Aspirin Therapy for You?
- JUL 7, 2013 Duke Today
  
  Is Aspirin Therapy for You?
- JUL 5, 2013 Charlotte Observer
  
  Duke researchers: Aspirin helps only some prevent heart disease, stroke
- JUL 5, 2013 Charlotte Observer
  
  Duke researchers: Aspirin helps only some prevent heart disease, stroke
Expertise
Subject Headings
Research
Selected Grants
- Hematology & Transfusion Medicine (T32) awarded by National Institutes of Health 1975 - 2026
- Molecular predictors of resistance and vulnerability to cardiovascular events in stable ischemic heart disease awarded by NYU Langone Medical Center 2022 - 2023
- Building and Deploying a Genomic-Medicine Risk Assessment Model for Diverse Primary Care Populations. awarded by National Institutes of Health 2018 - 2023
- Postdoctoral Training in Genomic Medicine Research awarded by National Institutes of Health 2017 - 2023
- Multidisciplinary Heart and Vascular Diseases awarded by National Institutes of Health 1975 - 2023
- Human Platelet Defects in Transcription Factor RUNX1 Haplodeficiency awarded by Temple University 2019 - 2022
- Abbott Diagnostics Collaborative Sponsored Research Agreement awarded by Abbott Laboratories 2016 - 2022
- Identifying on and off-target effects of ticagrelor on megakaryocytic gene expression awarded by AstraZeneca AB 2019 - 2021
- Pharmacogenetic Testing: Challenges of Clinical Integration awarded by National Institutes of Health 2011 - 2020
- Ex vivo metabolomic profiling of statin-induced myopathy awarded by American Heart Association 2017 - 2019
- Developing An In Vitro Human Myobundle Model Of Rheumatoid Arthritis awarded by National Institutes of Health 2017 - 2019
- Rap1 signaling in platelet homeostasis and vascular hemostasis awarded by University of North Carolina - Chapel Hill 2016 - 2019
- Development of Prognostic Platelet RNA Biomarkers To Tailor Antiplatelet Therapy awarded by National Institutes of Health 2013 - 2019
- DEVELOPMENT OF PLATELET RNA BIOMARKERS FOR THE RESPONSE TO TICAGRELOR awarded by AstraZeneca Healthcare Foundation 2015 - 2018
- Understanding the Response to Fesoterodine through Genetic Evaluation in the Elderly (URGE) awarded by National Institutes of Health 2012 - 2013
- Phase I Clinical Trial Describing the Pharmacogenomics of Aspirin awarded by National Institutes of Health 2009 - 2012
- Duke CTSA-KL2 awarded by National Institutes of Health 2006 - 2012
External Relationships
- Genome Medical
- Sanford Health
- United Healthcare
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Chanfreau-Coffinier, Catherine, Sony Tuteja, Leland E. Hull, Sally MacDonald, Olga Efimova, Jill Bates, Deepak Voora, David W. Oslin, Scott L. DuVall, and Julie A. Lynch. “Drug-drug-gene interaction risk among opioid users in the U.S. Department of Veterans Affairs.” Pain 163, no. 12 (December 1, 2022): 2390–97. https://doi.org/10.1097/j.pain.0000000000002637.
    Full Text Link to Item
  - Karády, Julia, Maros Ferencik, Thomas Mayrhofer, Nandini M. Meyersohn, Daniel O. Bittner, Pedro V. Staziaki, Balint Szilveszter, et al. “Risk factors for cardiovascular disease among individuals with hepatic steatosis.” Hepatology Communications 6, no. 12 (December 2022): 3406–20. https://doi.org/10.1002/hep4.2090.
    Full Text
  - Heffron, Sean P., Joseph Windheim, Tessa J. Barrett, Deepak Voora, and Jeffrey S. Berger. “Platelet inhibition by low-dose aspirin is not influenced by body mass or weight.” Platelets 33, no. 8 (November 17, 2022): 1208–13. https://doi.org/10.1080/09537104.2022.2087868.
    Full Text Link to Item
  - Cavallari, Larisa H., Emily Cicali, Kristin Wiisanen, Roger B. Fillingim, Hrishikesh Chakraborty, Rachel A. Myers, Kathryn V. Blake, et al. “Implementing a pragmatic clinical trial to tailor opioids for acute pain on behalf of the IGNITE ADOPT PGx investigators.” Clin Transl Sci 15, no. 10 (October 2022): 2479–92. https://doi.org/10.1111/cts.13376.
    Full Text Link to Item
  - Newman, Jonathan D., Pamela S. Douglas, Ilya Zhbannikov, Maros Ferencik, Borek Foldyna, Udo Hoffmann, Svati H. Shah, Geoffrey S. Ginsburg, Michael T. Lu, and Deepak Voora. “Associations of a polygenic risk score with coronary artery disease phenotypes in the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) trial.” Am Heart J 252 (October 2022): 12–15. https://doi.org/10.1016/j.ahj.2022.05.012.
    Full Text Link to Item
  - Ferencik, Maros, Thomas Mayrhofer, Michael T. Lu, Daniel O. Bittner, Hamed Emami, Stefan B. Puchner, Nandini M. Meyersohn, et al. “Coronary Atherosclerosis, Cardiac Troponin, and Interleukin-6 in Patients With Chest Pain: The PROMISE Trial Results.” Jacc Cardiovasc Imaging 15, no. 8 (August 2022): 1427–38. https://doi.org/10.1016/j.jcmg.2022.03.016.
    Full Text Link to Item
  - Stingl, Cory, Jeffrey A. Dvergsten, Simon W. M. Eng, Rae S. M. Yeung, Marvin J. Fritzler, Thomas Mason, Cynthia Crowson, Deepak Voora, and Ann M. Reed. “Gene Expression Profiles of Treatment Response and Non-Response in Children With Juvenile Dermatomyositis.” Acr Open Rheumatol 4, no. 8 (August 2022): 671–81. https://doi.org/10.1002/acr2.11445.
    Full Text Link to Item
  - Oslin, David W., Kevin G. Lynch, Mei-Chiung Shih, Erin P. Ingram, Laura O. Wray, Sara R. Chapman, Henry R. Kranzler, et al. “Effect of Pharmacogenomic Testing for Drug-Gene Interactions on Medication Selection and Remission of Symptoms in Major Depressive Disorder: The PRIME Care Randomized Clinical Trial.” Jama 328, no. 2 (July 12, 2022): 151–61. https://doi.org/10.1001/jama.2022.9805.
    Full Text Link to Item
  - Limkakeng, Alexander T., Laura-Leigh Rowlette, Ace Hatch, Andrew B. Nixon, Olga Ilkayeva, David Corcoran, Jennifer Modliszewski, Shannon Michelle Griffin, Geoffrey S. Ginsburg, and Deepak Voora. “A precision medicine approach to stress testing using metabolomics and microribonucleic acids.” Per Med 19, no. 4 (July 2022): 287–97. https://doi.org/10.2217/pme-2021-0021.
    Full Text Link to Item
  - Dong, Olivia M., Kevin A. Friede, Catherine Chanfreau-Coffinier, and Deepak Voora. “Cost-effectiveness of CYP2C19-guided P2Y12 inhibitors in Veterans undergoing percutaneous coronary intervention for acute coronary syndromes.” Eur Heart J Qual Care Clin Outcomes, June 2, 2022. https://doi.org/10.1093/ehjqcco/qcac031.
    Full Text Link to Item
  - Friede, Kevin A., Rachel A. Myers, Jordan Gales, Ilya Zhbannikov, Thomas L. Ortel, Svati H. Shah, William E. Kraus, Geoffrey S. Ginsburg, and Deepak Voora. “An antiplatelet response gene expression signature is associated with bleeding.” Cardiovasc Res, May 16, 2022. https://doi.org/10.1093/cvr/cvac079.
    Full Text Link to Item
  - Cooper-DeHoff, Rhonda M., Mikko Niemi, Laura B. Ramsey, Jasmine A. Luzum, E Katriina Tarkiainen, Robert J. Straka, Li Gong, et al. “The Clinical Pharmacogenetics Implementation Consortium Guideline for SLCO1B1, ABCG2, and CYP2C9 genotypes and Statin-Associated Musculoskeletal Symptoms.” Clin Pharmacol Ther 111, no. 5 (May 2022): 1007–21. https://doi.org/10.1002/cpt.2557.
    Full Text Link to Item
  - Myers, Rachel A., Thomas L. Ortel, Alexander Waldrop, Sandeep Dave, Geoffrey S. Ginsburg, and Deepak Voora. “Aspirin effects on platelet gene expression are associated with a paradoxical, increase in platelet function.” British Journal of Clinical Pharmacology 88, no. 5 (May 2022): 2074–83. https://doi.org/10.1111/bcp.15127.
    Full Text
  - Voora, Deepak, Jordan Baye, Adam McDermaid, Smitha Narayana Gowda, Russell A. Wilke, Anna Nicole Myrmoe, Catherine Hajek, and Eric A. Larson. “SLCO1B1*5 Allele Is Associated With Atorvastatin Discontinuation and Adverse Muscle Symptoms in the Context of Routine Care.” Clin Pharmacol Ther 111, no. 5 (May 2022): 1075–83. https://doi.org/10.1002/cpt.2527.
    Full Text Link to Item
  - Dong, Olivia M., Pradeep J. Poonnen, David Winski, Shelby D. Reed, Vishal Vashistha, Jill Bates, Michael J. Kelley, and Deepak Voora. “Cost-Effectiveness of Tumor Genomic Profiling to Guide First-Line Targeted Therapy Selection in Patients With Metastatic Lung Adenocarcinoma.” Value Health 25, no. 4 (April 2022): 582–94. https://doi.org/10.1016/j.jval.2021.09.017.
    Full Text Link to Item
  - Smilowitz, Nathaniel R., MacIntosh Cornwell, Erik J. Offerman, Caron B. Rockman, Svati H. Shah, Jonathan D. Newman, Kelly Ruggles, Deepak Voora, and Jeffrey S. Berger. “Risk factors, transcriptomics, and outcomes of myocardial injury following lower extremity revascularization.” Scientific Reports 12, no. 1 (April 2022): 6718. https://doi.org/10.1038/s41598-022-10241-9.
    Full Text
  - Dong, Olivia M., Megan C. Roberts, R Ryanne Wu, Corrine I. Voils, Nina Sperber, Kara L. Gavin, Jill Bates, et al. “Evaluation of the Veterans Affairs Pharmacogenomic Testing for Veterans (PHASER) clinical program at initial test sites.” Pharmacogenomics 22, no. 17 (November 2021): 1121–33. https://doi.org/10.2217/pgs-2021-0089.
    Full Text Link to Item
  - Limkakeng, Alexander T., Pratik Manandhar, Alaatin Erkanli, Stephanie A. Eucker, Adam Root, and Deepak Voora. “United States Emergency Department Use of Medications with Pharmacogenetic Recommendations.” West J Emerg Med 22, no. 6 (September 23, 2021): 1347–54. https://doi.org/10.5811/westjem.2021.5.51248.
    Full Text Open Access Copy Link to Item
  - Barrett, Tessa J., MacIntosh Cornwell, Khrystyna Myndzar, Christina C. Rolling, Yuhe Xia, Kamelia Drenkova, Antoine Biebuyck, et al. “Platelets amplify endotheliopathy in COVID-19.” Science Advances 7, no. 37 (September 2021): eabh2434. https://doi.org/10.1126/sciadv.abh2434.
    Full Text
  - Ginsburg, Geoffrey S., Larisa H. Cavallari, Hrishikesh Chakraborty, Rhonda M. Cooper-DeHoff, Paul R. Dexter, Michael T. Eadon, Bart S. Ferket, et al. “Establishing the value of genomics in medicine: the IGNITE Pragmatic Trials Network.” Genet Med 23, no. 7 (July 2021): 1185–91. https://doi.org/10.1038/s41436-021-01118-9.
    Full Text Open Access Copy Link to Item
  - Meyersohn, Nandini M., Thomas Mayrhofer, Kathleen E. Corey, Daniel O. Bittner, Pedro V. Staziaki, Balint Szilveszter, Travis Hallett, et al. “Association of Hepatic Steatosis With Major Adverse Cardiovascular Events, Independent of Coronary Artery Disease.” Clin Gastroenterol Hepatol 19, no. 7 (July 2021): 1480-1488.e14. https://doi.org/10.1016/j.cgh.2020.07.030.
    Full Text Link to Item
  - Dong, Olivia M., Jill Bates, Catherine Chanfreau-Coffinier, Michael Naglich, Michael J. Kelley, Laurence J. Meyer, Michael Icardi, et al. “Veterans Affairs Pharmacogenomic Testing for Veterans (PHASER) clinical program.” Pharmacogenomics 22, no. 3 (February 2021): 137–44. https://doi.org/10.2217/pgs-2020-0173.
    Full Text Link to Item
  - Infeld, Margaret, Kevin A. Friede, Tan Ru San, Holly J. Knickerbocker, Geoffrey S. Ginsburg, Thomas L. Ortel, and Deepak Voora. “Platelet reactivity in response to aspirin and ticagrelor in African-Americans and European-Americans.” J Thromb Thrombolysis 51, no. 2 (February 2021): 249–59. https://doi.org/10.1007/s11239-020-02327-w.
    Full Text Link to Item
  - Haga, Susanne B., Rachel Mills, Jivan Moaddeb, Yiling Liu, and Deepak Voora. “Delivery of Pharmacogenetic Testing with or without Medication Therapy Management in a Community Pharmacy Setting.” Pharmgenomics Pers Med 14 (2021): 785–96. https://doi.org/10.2147/PGPM.S314961.
    Full Text Link to Item
  - Haga, Susanne B., Rachel Mills, Jivan Moaddeb, Yiling Liu, and Deepak Voora. “Independent Community Pharmacists' Experience in Offering Pharmacogenetic Testing.” Pharmacogenomics and Personalized Medicine 14 (January 2021): 877–86. https://doi.org/10.2147/pgpm.s314972.
    Full Text
  - Patel, Jai N., Deepak Voora, Gillian Bell, Jill Bates, Amber Cipriani, Lisa Bendz, Amber Frick, et al. “North Carolina's multi-institutional pharmacogenomics efforts with the North Carolina Precision Health Collaborative.” Pharmacogenomics 22, no. 2 (January 2021): 73–80. https://doi.org/10.2217/pgs-2020-0156.
    Full Text Link to Item
  - Hull, Leland E., Jason L. Vassy, Annjanette Stone, Catherine C. Chanfreau-Coffinier, Craig W. Heise, Victoria M. Pratt, Ronald Przygodzki, et al. “Identifying End Users' Preferences about Structuring Pharmacogenetic Test Orders in an Electronic Health Record System.” J Mol Diagn 22, no. 10 (October 2020): 1264–71. https://doi.org/10.1016/j.jmoldx.2020.06.015.
    Full Text Link to Item
  - Friede, Kevin A., Margaret M. Infeld, Ru San Tan, Holly J. Knickerbocker, Rachel A. Myers, Laura G. Dubois, J Will Thompson, et al. “Influence of Sex on Platelet Reactivity in Response to Aspirin.” J Am Heart Assoc 9, no. 14 (July 21, 2020): e014726. https://doi.org/10.1161/JAHA.119.014726.
    Full Text Link to Item
  - Root, Adam, Randall Johnson, Ann McGee, Hui-Jie Lee, Siyun Yang, and Deepak Voora. “Understanding the state of pharmacogenomic testing for thiopurine methyltransferase within a large health system.” Pharmacogenomics 21, no. 6 (April 2020): 411–18. https://doi.org/10.2217/pgs-2019-0148.
    Full Text Link to Item
  - Rondina, Matthew T., Deepak Voora, Lukas M. Simon, Hansjörg Schwertz, Julie F. Harper, Olivia Lee, Seema C. Bhatlekar, et al. “Longitudinal RNA-Seq Analysis of the Repeatability of Gene Expression and Splicing in Human Platelets Identifies a Platelet SELP Splice QTL.” Circ Res 126, no. 4 (February 14, 2020): 501–16. https://doi.org/10.1161/CIRCRESAHA.119.315215.
    Full Text Link to Item
  - Ananthakumar, Anandita, Yiling Liu, Cristina E. Fernandez, George A. Truskey, and Deepak Voora. “Modeling statin myopathy in a human skeletal muscle microphysiological system.” Plos One 15, no. 11 (2020): e0242422. https://doi.org/10.1371/journal.pone.0242422.
    Full Text Link to Item
  - Dong, Olivia M., Stephanie B. Wheeler, Gracelyn Cruden, Craig R. Lee, Deepak Voora, Stacie B. Dusetzina, and Tim Wiltshire. “Cost-Effectiveness of Multigene Pharmacogenetic Testing in Patients With Acute Coronary Syndrome After Percutaneous Coronary Intervention.” Value Health 23, no. 1 (January 2020): 61–73. https://doi.org/10.1016/j.jval.2019.08.002.
    Full Text Link to Item
  - Eudy, A. M., D. Voora, R. A. Myers, and M. E. B. Clowse. “Effect of aspirin response signature gene expression on preterm birth and preeclampsia among women with lupus: a pilot study.” Lupus 28, no. 14 (December 2019): 1640–47. https://doi.org/10.1177/0961203319886069.
    Full Text Link to Item
  - Friede, Kevin A., and Deepak Voora. “Genetic influences on aspirin response in patients undergoing percutaneous coronary intervention.” Cardiovasc Res 115, no. 10 (August 1, 2019): 1452–53. https://doi.org/10.1093/cvr/cvz110.
    Full Text Link to Item
  - Limkakeng, Alexander T., Ricardo Henao, Deepak Voora, Thomas O’Connell, Michelle Griffin, Ephraim L. Tsalik, Svati Shah, Christopher W. Woods, and Geoffrey S. Ginsburg. “Pilot study of myocardial ischemia-induced metabolomic changes in emergency department patients undergoing stress testing.” Plos One 14, no. 2 (2019): e0211762. https://doi.org/10.1371/journal.pone.0211762.
    Full Text Open Access Copy Link to Item
  - Parker, William A. E., Niclas Eriksson, Richard C. Becker, Deepak Voora, Axel Åkerblom, Anders Himmelmann, Stefan K. James, Lars Wallentin, Robert F. Storey, and Robert F. PLATO Investigators. “Equilibrative nucleoside transporter 1 gene polymorphisms and clinical outcomes following acute coronary syndromes: findings from the PLATelet inhibition and patient Outcomes (PLATO) study.” Platelets 30, no. 5 (2019): 579–88. https://doi.org/10.1080/09537104.2018.1478404.
    Full Text Link to Item
  - Peyser, Bruce, Emily P. Perry, Kavisha Singh, Rosalynn D. Gill, Michael R. Mehan, Susanne B. Haga, Michael D. Musty, et al. “Effects of Delivering SLCO1B1 Pharmacogenetic Information in Randomized Trial and Observational Settings.” Circ Genom Precis Med 11, no. 9 (September 2018): e002228. https://doi.org/10.1161/CIRCGEN.118.002228.
    Full Text Link to Item
  - Friede, Kevin A., and Deepak Voora. “Future directions in pharmacogenomics discovery in cardiovascular disease.” Pharmacogenomics 19, no. 5 (April 2018): 375–77. https://doi.org/10.2217/pgs-2018-0002.
    Full Text Link to Item
  - Voora, Deepak, and Richard C. Becker. “Unraveling the Genetic Basis of Recurrent Venous Thromboembolism.” Circulation: Genomic and Precision Medicine 11, no. 2 (February 2018). https://doi.org/10.1161/circgen.117.002047.
    Full Text
  - Cavallari, Larisa H., Craig R. Lee, Amber L. Beitelshees, Rhonda M. Cooper-DeHoff, Julio D. Duarte, Deepak Voora, Stephen E. Kimmel, et al. “Multisite Investigation of Outcomes With Implementation of CYP2C19 Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention.” Jacc Cardiovasc Interv 11, no. 2 (January 22, 2018): 181–91. https://doi.org/10.1016/j.jcin.2017.07.022.
    Full Text Link to Item
  - Wingrove, James A., Karen Fitch, Brian Rhees, Steven Rosenberg, and Deepak Voora. “Peripheral blood gene expression signatures which reflect smoking and aspirin exposure are associated with cardiovascular events.” Bmc Med Genomics 11, no. 1 (January 12, 2018): 1. https://doi.org/10.1186/s12920-017-0318-6.
    Full Text Link to Item
  - Mao, Guangfen, Natthapol Songdej, Deepak Voora, Lawrence E. Goldfinger, Fabiola E. Del Carpio-Cano, Rachel A. Myers, and A Koneti Rao. “Transcription Factor RUNX1 Regulates Platelet PCTP (Phosphatidylcholine Transfer Protein): Implications for Cardiovascular Events: Differential Effects of RUNX1 Variants.” Circulation 136, no. 10 (September 5, 2017): 927–39. https://doi.org/10.1161/CIRCULATIONAHA.116.023711.
    Full Text Link to Item
  - Friede, Kevin, and Deepak Voora. “The need for sex-specific precision biomarkers for antiplatelet therapies.” Future Cardiol 13, no. 5 (September 2017): 419–22. https://doi.org/10.2217/fca-2017-0043.
    Full Text Link to Item
  - Musunuru, Kiran, Erik Ingelsson, Myriam Fornage, Peter Liu, Anne M. Murphy, L Kristin Newby, Christopher Newton-Cheh, et al. “The Expressed Genome in Cardiovascular Diseases and Stroke: Refinement, Diagnosis, and Prediction: A Scientific Statement From the American Heart Association.” Circ Cardiovasc Genet 10, no. 4 (August 2017). https://doi.org/10.1161/HCG.0000000000000037.
    Full Text Link to Item
  - Cavallari, L. H., A. L. Beitelshees, K. V. Blake, L. G. Dressler, J. D. Duarte, A. Elsey, J. N. Eichmeyer, et al. “The IGNITE Pharmacogenetics Working Group: An Opportunity for Building Evidence with Pharmacogenetic Implementation in a Real-World Setting.” Clin Transl Sci 10, no. 3 (May 2017): 143–46. https://doi.org/10.1111/cts.12456.
    Full Text Link to Item
  - Haga, Susanne B., Jivan Moaddeb, Rachel Mills, and Deepak Voora. “Assessing feasibility of delivering pharmacogenetic testing in a community pharmacy setting.” Pharmacogenomics 18, no. 4 (March 2017): 327–35. https://doi.org/10.2217/pgs-2016-0175.
    Full Text Link to Item
  - Voora, Deepak, Adrian Coles, Kerry L. Lee, Udo Hoffmann, James A. Wingrove, Brian Rhees, Lin Huang, et al. “An age- and sex-specific gene expression score is associated with revascularization and coronary artery disease: Insights from the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) trial.” American Heart Journal 184 (February 2017): 133–40. https://doi.org/10.1016/j.ahj.2016.11.004.
    Full Text
  - Lucas, Joseph E., Taylor C. Bazemore, Celan Alo, Patrick B. Monahan, and Deepak Voora. “An electronic health record based model predicts statin adherence, LDL cholesterol, and cardiovascular disease in the United States Military Health System.” Plos One 12, no. 11 (2017): e0187809. https://doi.org/10.1371/journal.pone.0187809.
    Full Text Link to Item
  - Friede, Kevin, Josephine Li, and Deepak Voora. “Use of Pharmacogenetic Information in the Treatment of Cardiovascular Disease.” Clin Chem 63, no. 1 (January 2017): 177–85. https://doi.org/10.1373/clinchem.2016.255232.
    Full Text Link to Item
  - Singh, Kavisha, Bruce Peyser, Gloria Trujillo, Nicholas Milazzo, Dillon Savard, Susanne B. Haga, Michael Musty, and Deepak Voora. “Rationale and design of the SLCO1B1 genotype guided statin therapy trial.” Pharmacogenomics 17, no. 17 (November 2016): 1873–80. https://doi.org/10.2217/pgs-2016-0065.
    Full Text Link to Item
  - Doran, Bethany, and Deepak Voora. “Circulating extracellular vesicles containing miRNAs may have utility as early biomarkers for cardiac injury.” Ann Transl Med 4, no. Suppl 1 (October 2016): S60. https://doi.org/10.21037/atm.2016.10.55.
    Full Text Link to Item
  - Voora, Deepak, A Koneti Rao, Gauthami S. Jalagadugula, Rachel Myers, Emily Harris, Thomas L. Ortel, and Geoffrey S. Ginsburg. “Systems Pharmacogenomics Finds RUNX1 Is an Aspirin-Responsive Transcription Factor Linked to Cardiovascular Disease and Colon Cancer.” Ebiomedicine 11 (September 2016): 157–64. https://doi.org/10.1016/j.ebiom.2016.08.021.
    Full Text Link to Item
  - Voora, Deepak, and Svati H. Shah. “Pharmacometabolomics Meets Genetics: A "Natural" Clinical Trial of Statin Effects.” J Am Coll Cardiol 67, no. 10 (March 15, 2016): 1211–13. https://doi.org/10.1016/j.jacc.2016.01.022.
    Full Text Link to Item
  - Xie, Gaoqiang, Phyo Kyaw Myint, Deepak Voora, Daniel T. Laskowitz, Ping Shi, Fuxiu Ren, Hao Wang, et al. “Genome-wide association study on progression of carotid artery intima media thickness over 10 years in a Chinese cohort.” Atherosclerosis 243, no. 1 (November 2015): 30–37. https://doi.org/10.1016/j.atherosclerosis.2015.08.034.
    Full Text Link to Item
  - Friede, Kevin A., Geoffrey S. Ginsburg, and Deepak Voora. “Gene Expression Signatures and the Spectrum of Coronary Artery Disease.” J Cardiovasc Transl Res 8, no. 6 (August 2015): 339–52. https://doi.org/10.1007/s12265-015-9640-6.
    Full Text Link to Item
  - Varenhorst, Christoph, Niclas Eriksson, Åsa Johansson, Bryan J. Barratt, Emil Hagström, Axel Åkerblom, Ann-Christine Syvänen, et al. “Effect of genetic variations on ticagrelor plasma levels and clinical outcomes.” Eur Heart J 36, no. 29 (August 1, 2015): 1901–12. https://doi.org/10.1093/eurheartj/ehv116.
    Full Text Link to Item
  - Beitelshees, Amber L., Deepak Voora, and Joshua P. Lewis. “Personalized antiplatelet and anticoagulation therapy: applications and significance of pharmacogenomics.” Pharmgenomics Pers Med 8 (2015): 43–61. https://doi.org/10.2147/PGPM.S52900.
    Full Text Link to Item
  - Wang, Zhi, Arnab Maity, Chuhsing Kate Hsiao, Deepak Voora, Rima Kaddurah-Daouk, and Jung-Ying Tzeng. “Module-based association analysis for omics data with network structure.” Plos One 10, no. 3 (2015): e0122309. https://doi.org/10.1371/journal.pone.0122309.
    Full Text Link to Item
  - Li, Josephine H., Sunil Suchindran, Svati H. Shah, William E. Kraus, Geoffrey S. Ginsburg, and Deepak Voora. “SLCO1B1 genetic variants, long-term low-density lipoprotein cholesterol levels and clinical events in patients following cardiac catheterization.” Pharmacogenomics 16, no. 5 (2015): 449–58. https://doi.org/10.2217/pgs.15.2.
    Full Text Link to Item
  - Rose, Jason J., Deepak Voora, Derek D. Cyr, Joseph E. Lucas, Aimee K. Zaas, Christopher W. Woods, L Kristin Newby, William E. Kraus, and Geoffrey S. Ginsburg. “Gene Expression Profiles Link Respiratory Viral Infection, Platelet Response to Aspirin, and Acute Myocardial Infarction.” Plos One 10, no. 7 (2015): e0132259. https://doi.org/10.1371/journal.pone.0132259.
    Full Text Open Access Copy Link to Item
  - Suchindran, Sunil, Tiffany Himmel, Thomas L. Ortel, Richard C. Becker, William E. Kraus, L. K. Newby, Geoffrey S. Ginsburg, and Deepak Voora. “Aspirin-Responsive Platelet Genes Are Associated With Platelet Function and Cardiovascular Events.” Circulation 130 (November 25, 2014).
    Link to Item
  - Alfirevic, A., D. Neely, J. Armitage, H. Chinoy, R. G. Cooper, R. Laaksonen, D. F. Carr, et al. “Phenotype standardization for statin-induced myotoxicity.” Clin Pharmacol Ther 96, no. 4 (October 2014): 470–76. https://doi.org/10.1038/clpt.2014.121.
    Full Text Link to Item
  - Alfirevic, A., D. Neely, J. Armitage, H. Chinoy, R. G. Cooper, R. Laaksonen, D. F. Carr, et al. “Phenotype standardization for statin-induced myotoxicity.” Clinical Pharmacology and Therapeutics 96, no. 4 (October 1, 2014): 470–76. https://doi.org/10.1038/clpt.2014.121.
    Full Text
  - Ramsey, L. B., S. G. Johnson, K. E. Caudle, C. E. Haidar, D. Voora, R. A. Wilke, W. D. Maxwell, et al. “The clinical pharmacogenetics implementation consortium guideline for SLCO1B1 and simvastatin-induced myopathy: 2014 update.” Clin Pharmacol Ther 96, no. 4 (October 2014): 423–28. https://doi.org/10.1038/clpt.2014.125.
    Full Text Link to Item
  - Voora, Deepak, and Richard C. Becker. “A freeze on tailored antiplatelet therapy?” Circulation 129, no. 21 (May 27, 2014): 2088–90. https://doi.org/10.1161/CIRCULATIONAHA.114.009930.
    Full Text Link to Item
  - Kertai, Miklos D., Stephen A. Esper, Igor Akushevich, Deepak Voora, Geoffrey S. Ginsburg, Mark Stafford-Smith, Katherine Grichnik, et al. “Preoperative CYP2D6 metabolism-dependent β-blocker use and mortality after coronary artery bypass grafting surgery.” J Thorac Cardiovasc Surg 147, no. 4 (April 2014): 1368-1375.e3. https://doi.org/10.1016/j.jtcvs.2013.09.067.
    Full Text Open Access Copy Link to Item
  - Voora, Deepak. “Expression quantitative trait locus analysis identifies novel genes for statin myopathy.” Circ Cardiovasc Genet 7, no. 2 (April 2014): 220–21. https://doi.org/10.1161/CIRCGENETICS.114.000611.
    Full Text Link to Item
  - Varenhorst, Christoph, Niclas Eriksson, Åsa Johansson, Bryan Barratt, Axel Åkerblom, Emil Hagström, Ann-Christine Syvänen, et al. “TICAGRELOR PLASMA LEVELS BUT NOT CLINICAL OUTCOMES ARE ASSOCIATED WITH TRANSPORTER AND METABOLISM ENZYME GENETIC POLYMORPHISMS.” Journal of the American College of Cardiology 63, no. 12 (April 2014): A25–A25. https://doi.org/10.1016/s0735-1097(14)60025-5.
    Full Text
  - Li, Josephine H., Scott V. Joy, Susanne B. Haga, Lori A. Orlando, William E. Kraus, Geoffrey S. Ginsburg, and Deepak Voora. “Genetically guided statin therapy on statin perceptions, adherence, and cholesterol lowering: a pilot implementation study in primary care patients.” J Pers Med 4, no. 2 (March 27, 2014): 147–62. https://doi.org/10.3390/jpm4020147.
    Full Text Link to Item
  - Voora, D. “The last line of defense against atherosclerosis.” Science Translational Medicine 6, no. 228 (March 19, 2014). https://doi.org/10.1126/scitranslmed.3008868.
    Full Text
  - Voora, D. “Pharmacogenetics: PREDICTing the era of personalized medicine.” Science Translational Medicine 6, no. 222 (February 5, 2014). https://doi.org/10.1126/scitranslmed.3008567.
    Full Text
  - Voora, D. “A powerful (Re)purpose for genome-wide association studies.” Science Translational Medicine 6, no. 218 (January 8, 2014). https://doi.org/10.1126/scitranslmed.3008136.
    Full Text
  - Voora, Deepak, Geoffrey S. Ginsburg, and Axel Akerblom. “Platelet RNA as a novel biomarker for the response to antiplatelet therapy.” Future Cardiol 10, no. 1 (January 2014): 9–12. https://doi.org/10.2217/fca.13.90.
    Full Text Link to Item
  - Voora, D. “Cardiology: Silencing the sounds of hypertrophic cardiomyopathy.” Science Translational Medicine 5, no. 210 (November 6, 2013). https://doi.org/10.1126/scitranslmed.3007861.
    Full Text
  - Voora, Deepak, Derek Cyr, Joseph Lucas, Jen-Tsan Chi, Jennifer Dungan, Timothy A. McCaffrey, Richard Katz, et al. “Aspirin exposure reveals novel genes associated with platelet function and cardiovascular events.” J Am Coll Cardiol 62, no. 14 (October 1, 2013): 1267–76. https://doi.org/10.1016/j.jacc.2013.05.073.
    Full Text Link to Item
  - Voora, D. “Drug-induced aches and pains.” Science Translational Medicine 5, no. 204 (September 25, 2013). https://doi.org/10.1126/scitranslmed.3007631.
    Full Text
  - Zaas, Aimee K., Thomas Burke, Minhua Chen, Micah McClain, Bradly Nicholson, Timothy Veldman, Ephraim L. Tsalik, et al. “A host-based RT-PCR gene expression signature to identify acute respiratory viral infection.” Sci Transl Med 5, no. 203 (September 18, 2013): 203ra126. https://doi.org/10.1126/scitranslmed.3006280.
    Full Text Link to Item
  - Becker, R. C., D. Voora, and S. H. Shah. “Hemostasis and Thrombosis” 2 (August 29, 2013): 602–11. https://doi.org/10.1016/B978-0-12-382227-7.00052-5.
    Full Text
  - Voora, D. “XiAP-ping castration-resistant prostate cancer.” Science Translational Medicine 5, no. 192 (July 3, 2013). https://doi.org/10.1126/scitranslmed.3006880.
    Full Text
  - Voora, D. “A miR-aculous advance for a rare heart disorder.” Science Translational Medicine 5, no. 186 (May 22, 2013). https://doi.org/10.1126/scitranslmed.3006596.
    Full Text
  - Voora, D. “Diagnosis and prognosis a liquid solution for solid tumors.” Science Translational Medicine 5, no. 180 (April 10, 2013). https://doi.org/10.1126/scitranslmed.3006268.
    Full Text
  - Voora, Deepak. “A transcriptomics-informed genetic association study identifies RHOA in simvastatin-induced low-density lipoprotein cholesterol lowering.” Circ Cardiovasc Genet 6, no. 1 (February 2013): 137–38. https://doi.org/10.1161/CIRCGENETICS.111.000070.
    Full Text Link to Item
  - Mills, Rachel, Deepak Voora, Bruce Peyser, and Susanne B. Haga. “Delivering pharmacogenetic testing in a primary care setting.” Pharmgenomics Pers Med 6 (2013): 105–12. https://doi.org/10.2147/PGPM.S50598.
    Full Text Link to Item
  - Rose, J. J., D. Voora, D. D. Cyr, J. E. Lucas, A. K. Zaas, L. K. Newby, W. E. Kraus, and G. S. Ginsburg. “Blood Gene Expression Profiling Reveals An Association Between Viral Infection, Platelet Function, And Acute Myocardial Infarction.” American Journal of Respiratory and Critical Care Medicine 187 (January 1, 2013).
    Link to Item
  - Voora, Deepak. “Building the evidentiary framework for pharmacogenetic testing: is it time to move beyond randomized controlled trials?” Per Med 10, no. 1 (January 2013): 1–3. https://doi.org/10.2217/pme.12.105.
    Full Text Link to Item
  - Voora, Deepak, Derek Cyr, Joseph Lucas, Jen-Tsan Chi, Jennifer Dungan, Timothy McCaffrey, Richard Katz, et al. “Aspirin Exposure Reveals Novel Genes Associated with Platelet Function and Cardiovascular Events.” Circulation 126, no. 21 (November 20, 2012).
    Link to Item
  - Voora, Deepak, and Geoffrey S. Ginsburg. “Clinical application of cardiovascular pharmacogenetics.” J Am Coll Cardiol 60, no. 1 (July 3, 2012): 9–20. https://doi.org/10.1016/j.jacc.2012.01.067.
    Full Text Link to Item
  - Wilke, R. A., L. B. Ramsey, S. G. Johnson, W. D. Maxwell, H. L. McLeod, D. Voora, R. M. Krauss, et al. “The clinical pharmacogenomics implementation consortium: CPIC guideline for SLCO1B1 and simvastatin-induced myopathy.” Clin Pharmacol Ther 92, no. 1 (July 2012): 112–17. https://doi.org/10.1038/clpt.2012.57.
    Full Text Link to Item
  - Voora, Deepak, Thomas L. Ortel, Joseph E. Lucas, Jen-Tsan Chi, Richard C. Becker, and Geoffrey S. Ginsburg. “Time-dependent changes in non-COX-1-dependent platelet function with daily aspirin therapy.” J Thromb Thrombolysis 33, no. 3 (April 2012): 246–57. https://doi.org/10.1007/s11239-012-0683-0.
    Full Text Link to Item
  - Ahmad, Tariq, Deepak Voora, and Richard C. Becker. “The pharmacogenetics of antiplatelet agents: towards personalized therapy?” Nat Rev Cardiol 8, no. 10 (August 9, 2011): 560–71. https://doi.org/10.1038/nrcardio.2011.111.
    Full Text Link to Item
  - Voora, Deepak, and Geoffrey S. Ginsburg. “A hub for bench-to-bedside pharmacogenomic-based research.” Pharmacogenomics 12, no. 8 (August 2011): 1095–98. https://doi.org/10.2217/pgs.11.62.
    Full Text Link to Item
  - Voora, Deepak, John Horton, Svati H. Shah, Linda K. Shaw, and L Kristin Newby. “Polymorphisms associated with in vitro aspirin resistance are not associated with clinical outcomes in patients with coronary artery disease who report regular aspirin use.” Am Heart J 162, no. 1 (July 2011): 166-72.e1. https://doi.org/10.1016/j.ahj.2011.03.026.
    Full Text Link to Item
  - Ahmad, T., D. Voora, and R. C. Becker. “The pharmacogenetics of antiplatelet agents: towards personalized therapy?” Nature Reviews Cardiology, 2011.
  - Voora, Deepak, Thomas L. Ortel, Joseph E. Lucas, Jen-Tsan Chi, Richard C. Becker, and Geoffrey S. Ginsburg. “A Whole Blood RNA Signature Accurately Classifies Multiple Measures of Platelet Function on Aspirin in Healthy Volunteers and Highlights a Common Underlying Pathway.” Circulation 122, no. 21 (November 23, 2010).
    Link to Item
  - Wallace, Thomas W., Brett D. Atwater, James P. Daubert, Deepak Voora, Anna Lisa Crowley, Tristram D. Bahnson, and Patrick M. Hranitzky. “Prevalence and clinical characteristics associated with left atrial appendage thrombus in fully anticoagulated patients undergoing catheter-directed atrial fibrillation ablation.” J Cardiovasc Electrophysiol 21, no. 8 (August 1, 2010): 849–52. https://doi.org/10.1111/j.1540-8167.2010.01729.x.
    Full Text Link to Item
  - Ginsburg, Geoffrey S., and Deepak Voora. “The long and winding road to warfarin pharmacogenetic testing.” J Am Coll Cardiol 55, no. 25 (June 22, 2010): 2813–15. https://doi.org/10.1016/j.jacc.2010.04.006.
    Full Text Link to Item
  - Voora, D., D. C. Koboldt, C. R. King, P. A. Lenzini, C. S. Eby, R. Porche-Sorbet, E. Deych, et al. “A polymorphism in the VKORC1 regulator calumenin predicts higher warfarin dose requirements in African Americans.” Clin Pharmacol Ther 87, no. 4 (April 2010): 445–51. https://doi.org/10.1038/clpt.2009.291.
    Full Text Link to Item
  - Voora, D., and G. S. Ginsburg. “Pharmacogenetics of the response to statins.” Current Cardiovascular Risk Reports 3, no. 6 (December 1, 2009): 434–40. https://doi.org/10.1007/s12170-009-0064-1.
    Full Text
  - Kawamoto, Kensaku, Lori A. Orlando, Deepak Voora, David F. Lobach, Scott Joy, Alex Cho, and Geoffrey S. Ginsburg. “Evaluation of the PharmGKB knowledge base as a resource for efficiently assessing the clinical validity and utility of pharmacogenetic assays.” Amia Annu Symp Proc 2009 (November 14, 2009): 307–11.
    Link to Item
  - Voora, Deepak, Svati H. Shah, Ivan Spasojevic, Shazia Ali, Carol R. Reed, Benjamin A. Salisbury, and Geoffrey S. Ginsburg. “The SLCO1B1*5 genetic variant is associated with statin-induced side effects.” J Am Coll Cardiol 54, no. 17 (October 20, 2009): 1609–16. https://doi.org/10.1016/j.jacc.2009.04.053.
    Full Text Link to Item
  - Voora, Deepak, Svati H. Shah, Carol R. Reed, Jun Zhai, David R. Crosslin, Chad Messer, Benjamin A. Salisbury, and Geoffrey S. Ginsburg. “Pharmacogenetic predictors of statin-mediated low-density lipoprotein cholesterol reduction and dose response.” Circ Cardiovasc Genet 1, no. 2 (December 2008): 100–106. https://doi.org/10.1161/CIRCGENETICS.108.795013.
    Full Text Link to Item
  - Voora, Deepak, Shazia Ali, Svati H. Shah, Carol R. Reed, Benjamin Salisbury, and Geoffrey S. Ginsburg. “Association of Statin-Induced Musculoskeletal Side Effects with Sex and a Hepatic Uptake Transporter Reduced Function Allele, SLC01B1*5.” Circulation 118, no. 18 (October 28, 2008): S326–S326.
    Link to Item
  - Gage, B. F., C. Eby, J. A. Johnson, E. Deych, M. J. Rieder, P. M. Ridker, P. E. Milligan, et al. “Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin.” Clin Pharmacol Ther 84, no. 3 (September 2008): 326–31. https://doi.org/10.1038/clpt.2008.10.
    Full Text Link to Item
  - Gage, B. F., C. Eby, J. A. Johnson, E. Deych, M. J. Rieder, P. M. Ridker, P. E. Milligan, et al. “Corrigendum: Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin (Clinical Pharmacology Therapeutics (2008) 84, (326-331) DOI: 10.1038/clpt.2008.10).” Clinical Pharmacology and Therapeutics 84, no. 3 (September 1, 2008): 430. https://doi.org/10.1038/clpt.2008.112.
    Full Text
  - Voora, Deepalk, Carol R. Reed, Jun Zhai, Benjamin A. Salisbury, Svatj H. Shah, and Geoffrey S. Ginsburg. “Polymorphisms in ABCA1 predict statin mediated LDL cholesterol lowering and suggest an interaction with CETP.” Circulation 116, no. 16 (October 16, 2007): 178–178.
    Link to Item
  - Millican, Eric A., Petra A. Lenzini, Paul E. Milligan, Leonard Grosso, Charles Eby, Elena Deych, Gloria Grice, et al. “Genetic-based dosing in orthopedic patients beginning warfarin therapy.” Blood 110, no. 5 (September 1, 2007): 1511–15. https://doi.org/10.1182/blood-2007-01-069609.
    Full Text Link to Item
  - Voora, Deepak, and Brian F. Gage. “Is primary care ready for pharmacogenetics?” Pharmacogenomics 7, no. 1 (January 2006): 1–3. https://doi.org/10.2217/14622416.7.1.1.
    Full Text Link to Item
  - Voora, Deepak, Howard L. McLeod, Charles Eby, and Brian F. Gage. “The pharmacogenetics of coumarin therapy.” Pharmacogenomics 6, no. 5 (July 2005): 503–13. https://doi.org/10.2217/14622416.6.5.503.
    Full Text Link to Item
  - Voora, Deepak, Charles Eby, Mark W. Linder, Paul E. Milligan, Bonny L. Bukaveckas, Howard L. McLeod, William Maloney, et al. “Prospective dosing of warfarin based on cytochrome P-450 2C9 genotype.” Thromb Haemost 93, no. 4 (April 2005): 700–705. https://doi.org/10.1160/TH04-08-0542.
    Full Text Link to Item
  - Voora, Deepak, Howard L. McLeod, Charles Eby, and Brian F. Gage. “Use of pharmacogenetics to guide warfarin therapy.” Drugs Today (Barc) 40, no. 3 (March 2004): 247–57. https://doi.org/10.1358/dot.2004.40.3.820088.
    Full Text Link to Item
  - Voora, Deepak, and Anitha Vijayan. “Mesenteric vein thrombosis associated with intravaginal contraceptives: a case report and review of the literature.” J Thromb Thrombolysis 15, no. 2 (April 2003): 105–8. https://doi.org/10.1023/b:thro.0000003323.80742.4d.
    Full Text Link to Item
  - Saker, F., D. M. Voora, S. D. Mahajan, I. Kiliç, F. Ismail-Beigi, and S. C. Kalhan. “Effect of reduced inspired oxygen on fetal growth and maternal glucose metabolism in rat pregnancy.” Metabolism 48, no. 6 (June 1999): 738–44. https://doi.org/10.1016/s0026-0495(99)90173-7.
    Full Text Link to Item
  - Bardwell, L., J. G. Cook, J. X. Zhu-Shimoni, D. Voora, and J. Thorner. “Differential regulation of transcription: repression by unactivated mitogen-activated protein kinase Kss1 requires the Dig1 and Dig2 proteins.” Proc Natl Acad Sci U S A 95, no. 26 (December 22, 1998): 15400–405. https://doi.org/10.1073/pnas.95.26.15400.
    Full Text Link to Item
  - Bardwell, L., J. G. Cook, D. Voora, D. M. Baggott, A. R. Martinez, and J. Thorner. “Repression of yeast Ste12 transcription factor by direct binding of unphosphorylated Kss1 MAPK and its regulation by the Ste7 MEK.” Genes Dev 12, no. 18 (September 15, 1998): 2887–98. https://doi.org/10.1101/gad.12.18.2887.
    Full Text Link to Item
- Book Sections
  - Li, J. H., and D. Voora. “Cardiovascular Pharmacogenetics.” In Genomic and Precision Medicine: Cardiovascular Disease: Third Edition, 291–307, 2018. https://doi.org/10.1016/B978-0-12-801812-5.00012-3.
    Full Text
  - Voora, D. “Pharmacogenetics and Pharmacogenomics.” In Genomic and Precision Medicine: Foundations, Translation, and Implementation: Third Edition, 233–46, 2017. https://doi.org/10.1016/B978-0-12-800681-8.00016-5.
    Full Text
  - Becker, R. C., D. Voora, and S. H. Shah. “Hemostasis and Thrombosis.” In Genomic and Personalized Medicine, 602–11, 2012. https://doi.org/10.1016/B978-0-12-382227-7.00052-5.
    Full Text
- Conference Papers
  - Dong, Olivia, Kevin Friede, Catherine Chanfreau-Coffinier, and Deepak Voora. “ONE-YEAR COST-EFFECTIVENESS OF CYP2C19-GUIDED DE-ESCALATION AND ESCALATION OF P2Y12 INHIBITORS IN VETERANS WITH ACUTE CORONARY SYNDROMES UNDERGOING PERCUTANEOUS CORONARY INTERVENTION.” In Journal of the American College of Cardiology, 77:3416–3416, 2021.
    Link to Item
  - Friede, Kevin A., Rachel A. Myers, Thomas Ortel, Geoffrey Ginsburg, and Deepak Voora. “AN ANTITHROMBOTIC RESPONSE SIGNATURE SCORE IS A GENE EXPRESSION BIOMARKER OF BLEEDING RISK.” In Journal of the American College of Cardiology, 77:15–15, 2021.
    Link to Item
  - Karady, Julia, Thomas Mayrhofer, Nandini Meyersohn, Daniel Bittner, Pedro V. Staziaki, Balint Szilveszter, Travis Hallett, et al. “SEDENTARY LIFESTYLE AND ATHEROSCLEROTIC CARDIOVASCULAR DISEASE RISK SCORE PREDICT INCIDENT MAJOR ADVERSE CARDIOVASCULAR EVENTS IN SUBJECTS WITH HEPATIC STEATOSIS.” In Gastroenterology, 160:S790–91, 2021.
    Link to Item
  - Chanfreau-Coffinier, Catherine, Tori Anglin-Foote, Kyung Min Lee, Zhenyu Lu, julie lynch, Mary E. Plomondon, Scott L. DuVall, et al. “Abstract 16710: CYP2C19 Polymorphisms and Clinical Outcomes Following Percutaneous Coronary Intervention (PCI) in the Million Veterans Program (MVP).” In Circulation, Vol. 142. Ovid Technologies (Wolters Kluwer Health), 2020. https://doi.org/10.1161/circ.142.suppl_3.16710.
    Full Text
  - Voora, Deepak, Jordan Baye, Adam D. Mcdermaid, Smitha N. Gowda, Larson A. Eric, and Wilke A. Russell. “Abstract 14950: SLCO1B1 Genotype is Associated With Atorvastatin Discontinuation.” In Circulation, Vol. 142. Ovid Technologies (Wolters Kluwer Health), 2020. https://doi.org/10.1161/circ.142.suppl_3.14950.
    Full Text
  - Limkakeng, AT Jr, I. Zhbannikov, P. S. Douglas, U. Hoffman, M. Ferencik, S. Shah, W. Kraus, L. Cooper, D. Voora, and G. S. Ginsburg. “Biomarker Profiling for Obstructive Coronary Artery Disease: A PROMISE Substudy.” In Annals of Emergency Medicine, 76:S116–S116, 2020.
    Link to Item
  - Poonnen, Pradeep, Olivia Dong, David Winski, Shelby D. Reed, Vishal Vashistha, Jill S. Bates, Michael J. Kelley, and Deepak Voora. “Cost-effectiveness of genomic profiling in veterans with metastatic lung adenocarcinoma.” In Journal of Clinical Oncology, Vol. 38, 2020.
    Link to Item
  - Limkakeng, A. T., L. -. L. Rowlette, O. Ilkayeva, J. Modliszewski, D. Corcoran, J. C. Leahy, S. M. Griffin, and D. Voora. “99EMF Pilot of Integrated Metabolomic and MicroRNA Analysis to Identify Myocardial Ischemia on Emergency Department Cardiac Stress Tests.” In Annals of Emergency Medicine, 74:S40–S40. Elsevier BV, 2019. https://doi.org/10.1016/j.annemergmed.2019.08.103.
    Full Text
  - Limkakeng, A. T., P. Manandhar, A. Erkanli, and D. Voora. “129 United States Emergency Department Use of Medications with Pharmacogenetic Recommendations.” In Annals of Emergency Medicine, 74:S52–S52. Elsevier BV, 2019. https://doi.org/10.1016/j.annemergmed.2019.08.134.
    Full Text
  - Liu, Yiling, Anandita Ananthakumar, Will Thompson, Rachel Myers, Rima Kaddurah-Daouk, Laura Dubois, George A. Truskey, and Deepak Voora. “Metabolomic Profiling of Engineered Skeletal Myobundles Identifies a Plasma Biomarker for Statin Associated Musculoskeletal Symptoms (SAMS).” In Circulation, Vol. 140, 2019.
    Link to Item
  - Dong, O., C. R. Lee, S. B. Wheeler, D. Voora, S. B. Dusetzina, and T. Wiltshire. “CV1 - A COST-EFFECTIVENESS ANALYSIS OF MULITI-GENE PHARMACOGENETIC TESTING IN ACUTE CORONARY SYNDROME PATIENTS FOLLOWING PERCUTANEOUS CORONARY INTERVENTION.” In Value in Health, 21:S6–S6. Elsevier BV, 2018. https://doi.org/10.1016/j.jval.2018.09.032.
    Full Text
  - Limkakeng, A. T., M. Griffin, C. Leahy, A. Hatch, L. Rowlette, D. Voora, and A. Nixon. “32EMF Isolating Micro-Ribonucleic Acids from Peripheral Plasma to Identify Myocardial Ischemia During Stress Testing in Emergency Department Patients.” In Annals of Emergency Medicine, 72:S16–S16. Elsevier BV, 2018. https://doi.org/10.1016/j.annemergmed.2018.08.037.
    Full Text
  - Myers, Rachel A., Thomas L. Ortel, Alexander Waldrop, Sandeep Dave, Geoffrey S. Ginsburg, and Deepak Voora. “Aspirin Responsive Platelet Genes Are Associated With Platelet Function and Reflect a Non-Cyclooxygenase Mediated Effect.” In Circulation, Vol. 138, 2018.
    Link to Item
  - Myers, Rachel A., Thomas L. Ortel, Alexander Waldrop, Sandeep Dave, Geoffrey S. Ginsburg, and Deepak Voora. “Ticagrelor Responsive Platelet Genes Are Associated With Platelet Function and Bleeding.” In Circulation, Vol. 138, 2018.
    Link to Item
  - Rowley, Jesse W., Robert A. Campbell, Hansjorg Schwertz, Andrew S. Weyrich, Neal D. Tolley, Deepak Voora, and Matthew T. Rondina. “Transcript Expression, Intron Retention, and RNA Editing Are Conserved in Human Platelets over a 4 Year Period.” In Blood, Vol. 130. AMER SOC HEMATOLOGY, 2017.
    Link to Item
  - Assimes, Themistocles L., Scott M. Damrauer, Jin Li, Yan Sun, Julie A. Lynch, Derek Klarin, Scott L. Duvall, et al. “A GWAS of EHR-Defined CAD Identifies Multiple Novel Loci Including the First 3 Loci on the X-Chromosome: The Million Veteran Program.” In Circulation, Vol. 136. LIPPINCOTT WILLIAMS & WILKINS, 2017.
    Link to Item
  - Li, Jin, Julie A. Lynch, Scott M. Damrauer, Mary E. Plomondon, Rebecca J. Song, Kelly Cho, Derek Klarin, et al. “Genetic Variants Associated With Angiographic Burden of CAD in Europeans and African Americans: The Million Veteran Program.” In Circulation, Vol. 136. LIPPINCOTT WILLIAMS & WILKINS, 2017.
    Link to Item
  - Wingrove, James A., Karen Fitch, Brian Rhees, Steven Rosenberg, and Deepak Voora. “Peripheral Blood Gene Expression Signatures Which Reflect Smoking and Response to Aspirin Are Associated With Cardiovascular Events.” In Circulation, Vol. 136. LIPPINCOTT WILLIAMS & WILKINS, 2017.
    Link to Item
  - Friede, Kevin, Margaret Infeld, Ru-San Tan, Rachel Myers, and Deepak Voora. “INFLUENCE OF SEX ON PLATELET RESPONSE TO ASPIRIN AND TICAGRELOR.” In Journal of the American College of Cardiology, 69:23–23. Elsevier BV, 2017. https://doi.org/10.1016/s0735-1097(17)33412-5.
    Full Text
  - Infeld, Margaret, Kevin Friede, Rachel A. Myers, Thomas Ortel, Tan Ru San, and Deepak Voora. “THE EFFECT OF RACE ON THE ANTIPLATELET EFFECTS OF TICAGRELOR AND ASPIRIN.” In Journal of the American College of Cardiology, 69:263–263. Elsevier BV, 2017. https://doi.org/10.1016/s0735-1097(17)33652-5.
    Full Text
  - Cavallari, Larisa H., Joshua C. Denny, Craig R. Lee, Amber L. Beitelshees, Julio D. Duarte, Steve E. Kimmel, Deepak Voora, et al. “Prospective Clinical Implementation of CYP2C19-Genotype Guided Antiplatelet Therapy After PCI: a Multi-Site Investigation of MACE Outcomes in a Real-World Setting.” In Circulation, 134:E711–12. LIPPINCOTT WILLIAMS & WILKINS, 2016.
    Link to Item
  - Songdej, Natthapol, Guangfen Mao, Deepak Voora, Lawrence E. Goldfinger, Fabiola Del Carpio-Cano, Rachel Myers, and Angara Koneti Rao. “PCTP (Phosphatidylcholine Transfer Protein) is Regulated By RUNX1 in Platelets/Megakaryocytes and is Associated with Adverse Cardiovascular Events.” In Blood, 128:365–365. American Society of Hematology, 2016. https://doi.org/10.1182/blood.v128.22.365.365.
    Full Text
  - Klarin, Derek, Yuk-Lam Ho, David R. Gagnon, Jacqueline Honerlaw, Jason L. Vassy, Deepak Voora, Tim Assimes, et al. “Lipid Reduction Measurements in a Veteran Population - Implications for Genetic Modeling in the Million Veteran Program.” In Circulation, Vol. 134. LIPPINCOTT WILLIAMS & WILKINS, 2016.
    Link to Item
  - Voora, Deepak, Emily Perry, Kavisha Singh, Gloria Trujillo, Nicholas Milazzo, Dillon Savard, Susanne Haga, Michael D. Musty, Yi-Ju Li, and Bruce Peyser. “SLCO1B1 Genotype-Guided Statin Therapy Lowers LDL Cholesterol in Patients With Statin-Intolerance-A Randomized Controlled Trial.” In Circulation, Vol. 134. LIPPINCOTT WILLIAMS & WILKINS, 2016.
    Link to Item
  - Voora, Deepak, Emily Perry, Kavisha Singh, Gloria Trujillo, Nicholas Milazzo, Dillon Savard, Susanne Haga, Michael D. Musty, Yi-Ju Li, and Bruce Peyser. “SLCO1B1 Genotype-Guided Statin Therapy Lowers LDL Cholesterol in Patients With Statin-Intolerance-A Randomized Controlled Trial.” In Circulation, Vol. 134. LIPPINCOTT WILLIAMS & WILKINS, 2016.
    Link to Item
  - Voora, Deepak, Adrian Coles, Kerry Lee, Udo Hoffmann, James Wingrove, Brian Rhees, Lin Huang, et al. “AN AGE- AND SEX-SPECIFIC PERIPHERAL BLOOD GENE EXPRESSION SCORE CORRELATES WITH FUTURE CARDIOVASCULAR EVENTS: INSIGHTS FROM THE PROMISE TRIAL.” In Journal of the American College of Cardiology, 67:2094–2094. Elsevier BV, 2016. https://doi.org/10.1016/s0735-1097(16)32095-2.
    Full Text
  - Li, Josephine H., Sunil Suchindran, Svati H. Shah, William E. Kraus, Geoffrey S. Ginsburg, and Deepak Voora. “Effect of SLCO1B1*5 on Low-Density Lipoprotein Cholesterol Levels and Long-Term Clinical Events in Patients During Statin Therapy Following Cardiac Catheterization.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.
    Link to Item
  - Doss, Jennifer, Dereje Jima, Deepak Voora, Sandeep Dave, and Jen-Tsan Ashley Chi. “Using High-Throughput Sequencing of Red Blood Cells and Platelets to Identify Micrornas Associated with Hematopoiesis.” In Blood, 120:2326–2326. American Society of Hematology, 2012. https://doi.org/10.1182/blood.v120.21.2326.2326.
    Full Text
  - Voora, Deepak, Svati H. Shah, John R. Horton, Linda K. Shaw, and L. K. Newby. “Polymorphisms Associated With in vitro Aspirin Resistance Are Not Associated With Clinical Outcomes During Regular Aspirin Use.” In Circulation, 120:S599–S599. LIPPINCOTT WILLIAMS & WILKINS, 2009.
    Link to Item
  - Voora, Deepak, Dan C. Koboldt, Cristi R. King, Charles S. Eby, Rhonda Porche-Sorbet, Elena Deych, Petra Lenzini, et al. “A comparative genomics approach identifies a polymorphism in calumenin as a predictor of high warfarin dose in African American patients.” In Circulation, 116:177–177. LIPPINCOTT WILLIAMS & WILKINS, 2007.
    Link to Item
  - Gage, B. F., C. S. Eby, J. A. Johnson, M. J. Rieder, P. M. Ridker, A. E. Rettie, C. Aquilante, et al. “Use of pharmacogenetics and clinical factors to predict the maintenance dose of warfarin.” In Blood, 106:164A-164A. AMER SOC HEMATOLOGY, 2005.
    Link to Item
- Preprints
  - Myers, Rachel A., Thomas L. Ortel, Alexander Waldrop, Sandeep Dave, Geoffrey S. Ginsburg, and Deepak Voora. “Ticagrelor responsive platelet genes are associated with platelet function and bleeding.” Cold Spring Harbor Laboratory, March 18, 2022. https://doi.org/10.1101/2022.03.18.22270280.
    Full Text

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.

Education, Training, & Certifications

Previous Appointments & Affiliations

In the News

Subject Headings

Selected Grants

External Relationships

Selected Publications

Academic Articles

Book Sections

Conference Papers

Preprints