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Denise Snyder

Assoc Dean, Clinical Research
School of Medicine
DUMC 104028, 2200 West Main Street, Durham, NC 27710
2200 West Main Street, Box 21, Durham, NC 27705

Selected Publications


Building Pathways to Clinical Research Careers: Partnerships With Academic Programs to Provide Students With Experiential Learning Opportunities in Clinical Research.

Journal Article Acad Med · July 28, 2025 PROBLEM: The practice of evidence-based medicine relies on clinical research to develop innovations in treatment and prevention. Clinical research professionals (CRPs) are critical to the development of safe and effective health interventions that guide me ... Full text Link to item Cite

Duke Research at Pickett: The evolution of a free-standing research site partnering with communities toward health equity advancement.

Journal Article J Clin Transl Sci · 2025 While clinical research intends to improve health outcomes for all, access to research participation is often limited and inequitable. Geographic proximity is a recognized barrier, thus, systemic infrastructure solutions through federal programs including ... Full text Open Access Link to item Cite

An interprofessional model for training the next generation of physician-researchers.

Journal Article J Clin Transl Sci · 2025 The potential for physicians, clinicians, and health professionals to contribute to the advancement of medical therapies through clinical research is significant. Yet, a lack of exposure to, or practical training in, the conduct of clinical research can in ... Full text Open Access Link to item Cite

Development of a job satisfaction measure for clinical research professionals: A mixed methods approach.

Journal Article Journal of clinical and translational science · January 2025 BackgroundClinical research professionals (CRPs) are essential members of research teams serving in multiple job roles. However, recent turnover rates have reached crisis proportions, negatively impacting clinical trial metrics. Gaining an underst ... Full text Cite

Trends in turnover and turbulence at a large academic medical center before and during COVID-19: Analyzing structured clinical research professional roles.

Journal Article Journal of clinical and translational science · January 2025 IntroductionHigh workforce turbulence has plagued clinical research, becoming intensified during the COVID-19 pandemic, especially for patient-facing workers. In a time of great uncertainty and risk among healthcare workers, researchers included, ... Full text Cite

The research equity and diversity initiative (READI): Changing the face of clinical research through community outreach and engagement.

Journal Article J Clin Transl Sci · 2025 Current evidence underscores a need to transform how we do clinical research, shifting from academic-driven priorities to co-led community partnership focused programs, accessible and relevant career pathway programs that expand opportunities for career de ... Full text Open Access Link to item Cite

A qualitative evaluation of the Research Equity and Diversity Initiative's (READI) research support voucher program and its community engagement support.

Journal Article J Clin Transl Sci · 2025 The Duke Research Equity and Diversity Initiative (READI) was established in 2021 to engage Durham and surrounding communities in clinical research and build capacity to promote equitable access to research participation. Within READI, a voucher program wa ... Full text Link to item Cite

Defining methods to improve eSource site start-up practices.

Journal Article Contemp Clin Trials Commun · December 2024 BACKGROUND: eSource software that transfers patient electronic health record data into a clinical trial electronic case report form holds promise for increasing data quality while reducing data collection, monitoring and source document verification costs. ... Full text Link to item Cite

A Method for Efficient De-identification of DICOM Metadata and Burned-in Pixel Text.

Journal Article J Imaging Inform Med · October 2024 De-identification of DICOM images is an essential component of medical image research. While many established methods exist for the safe removal of protected health information (PHI) in DICOM metadata, approaches for the removal of PHI "burned-in" to image ... Full text Link to item Cite

Methods for building a staff workforce of quantitative scientists in academic health care.

Journal Article Stat (Int Stat Inst) · June 2024 Collaborative quantitative scientists, including biostatisticians, epidemiologists, bio-informaticists, and data-related professionals, play vital roles in research, from study design to data analysis and dissemination. It is imperative that academic healt ... Full text Link to item Cite

Enhancing the clinical research workforce: a collaborative approach with human resources

Journal Article Frontiers in Pharmacology · January 1, 2024 Jobs for clinical research professionals (CRPs) have grown increasingly complex over the past 20+ years. This is due largely to additional administrative burden for investigators, study teams, sponsors, Clinical Research Organizations (CROs), and sites, pa ... Full text Cite

Now is the time to fix the clinical research workforce crisis.

Journal Article Clinical trials (London, England) · October 2023 The clinical and translational research enterprise is recognized by many as the "evidence generation system." While there have been several calls to revolutionize this enterprise to more effectively deliver the fruits of biomedical science to patients and ... Full text Cite

Leveraging retooled clinical research infrastructure for Clinical Research Management System implementation at a large Academic Medical Center.

Journal Article Journal of clinical and translational science · January 2023 Quality clinical research is essential for health care progress and is the mission of academic health centers. Yet ensuring quality depends on an institution's ability to measure, control, and respond to metrics of trial performance. Uninformed clinical re ... Full text Cite

Tackling standardization in clinical research workforce hiring using competency-based job classifications.

Journal Article Journal of clinical and translational science · January 2023 In 2016, Duke reconfigured its clinical research job descriptions and workforce to be competency-based, modeled around the Joint Taskforce for Clinical Trial Competency framework. To ensure consistency in job classification amongst new hires in the clinica ... Full text Cite

Development and implementation of an on-demand competency-based onboarding program for clinical research professionals in academic medicine

Journal Article Frontiers in Medicine · January 1, 2023 Over the past 7 years, Duke has implemented competency-based job classifications for clinical research professionals (CRPs) with a defined pathway for career advancement. The workforce is defined specifically as the collection of staff employed across the ... Full text Cite

Issues for recruitment and retention of clinical research professionals at academic medical centers: Part 1 - Collaborative conversations Un-Meeting findings

Journal Article Journal of Clinical and Translational Science · June 3, 2022 Background: Identification of evidence-based factors related to status of the clinical research professional (CRP) workforce at academic medical centers (AMCs) will provide context for National Center for Advancing Translational Science (NCATS) policy cons ... Full text Cite

Development and evaluation of a novel training program to build study staff skills in equitable and inclusive engagement, recruitment, and retention of clinical research participants.

Journal Article J Clin Transl Sci · 2022 BACKGROUND: Adequate equitable recruitment of underrepresented groups in clinical research and trials is a national problem and remains a daunting challenge to translating research discoveries into effective healthcare practices. Engagement, recruitment, a ... Full text Open Access Link to item Cite

Professional development for clinical research professionals: Implementation of a competency-based assessment model

Journal Article Journal of Research Administration · January 1, 2020 Aligning job descriptions at Duke University Schools of Medicine and Nursing with the Joint Task Force for Clinical Trial Competencies ( JTFCTC) spurred additional related activities—namely, establishing professional pathways and career ladders for clinica ... Cite

Rural-urban differences in health behaviors and outcomes among older, overweight, long-term cancer survivors in the RENEW randomized control trial.

Journal Article Cancer causes & control : CCC · April 2019 PurposeRural cancer survivors (RCS) have poorer health outcomes and face multiple challenges-older age, and limited transportation, education, income, and healthcare access. Yet, RCS are understudied. The Reach-out to ENhancE Wellness(RENEW) trial ... Full text Cite

Characteristics of cancer patients participating in presurgical lifestyle intervention trials exploring effects on tumor biology.

Journal Article Contemporary clinical trials communications · December 2017 BackgroundPoor diet and insufficient physical activity are strongly associated with an increased risk of several cancers. Preclinical studies suggest that lifestyle modifications may exert favorable effects on tumor biology. Randomized controlled ... Full text Cite

Effects of diet and exercise on weight-related outcomes for breast cancer survivors and their adult daughters: an analysis of the DAMES trial.

Journal Article Support Care Cancer · August 2017 PURPOSE: Few trials have aimed to promote diet and exercise behaviors in both cancer survivors and their family members and examine their associations with weight-related outcomes. We conducted a secondary analysis to examine associations between change in ... Full text Link to item Cite

Using Competencies to Transform Clinical Research Job Classifications

Journal Article Journal of Research Administration · 2017 Featured Publication Cite

Physical resilience of older cancer survivors: An emerging concept.

Journal Article J Geriatr Oncol · November 2016 OBJECTIVES: To characterize factors contributing to physical resilience in older cancer survivors, as demonstrated by resistance to decline or recovery (resilience). MATERIALS AND METHODS: We conducted a secondary analysis of data from a randomized control ... Full text Link to item Cite

Retooling institutional support infrastructure for clinical research.

Journal Article Contemporary clinical trials · May 2016 Featured Publication Clinical research activities at academic medical centers are challenging to oversee. Without effective research administration, a continually evolving set of regulatory and institutional requirements can divert investigator and study team attention away fr ... Full text Cite

Group trajectory analysis helps to identify older cancer survivors who benefit from distance-based lifestyle interventions.

Journal Article Cancer · December 15, 2015 BACKGROUND: The number of older cancer survivors is increasing as more adults survive to older ages. The objectives of this study were to examine trajectories of physical activity (PA) and physical function (PF) over a 2-year lifestyle counseling study and ... Full text Link to item Cite

Zinc and Vitamin Supplementation in an Under-5 Indigenous Population of Guatemala: Influence of Lay Health Promoters in Decreasing Incidence of Diarrhea.

Journal Article Journal of transcultural nursing : official journal of the Transcultural Nursing Society · September 2015 BackgroundMalnutrition is an urgent problem in the developing world, especially for children under 5 years of age. The article describes the utilization of a standard of practice designed to prevent illness in a malnourished, under-5 indigenous po ... Full text Cite

Disparate results between proliferation rates of surgically excised prostate tumors and an in vitro bioassay using sera from a positive randomized controlled trial.

Journal Article Biotech Histochem · April 2015 In vitro bioassay has been used extensively to test the effects of culturing cancer cells in sera from humans participating in dietary interventions, i.e, studies of modified intake of nutrients for the purpose of reducing cancer risk or progression. It ha ... Full text Link to item Cite

Clinical outcomes of splenectomy in children: report of the splenectomy in congenital hemolytic anemia registry.

Journal Article Am J Hematol · March 2015 The outcomes of children with congenital hemolytic anemia (CHA) undergoing total splenectomy (TS) or partial splenectomy (PS) remain unclear. In this study, we collected data from 100 children with CHA who underwent TS or PS from 2005 to 2013 at 16 sites i ... Full text Link to item Cite

ClinicalTrials.gov reporting: strategies for success at an academic health center.

Journal Article Clin Transl Sci · February 2015 The Food and Drug Administration Amendments Act of 2007 (FDAAA 2007, US Public Law 110-98) mandated registration and reporting of results for applicable clinical trials. Meeting these registration and results reporting requirements has proven to be a chall ... Full text Link to item Cite

Cancer survivors' uptake and adherence in diet and exercise intervention trials: an integrative data analysis.

Journal Article Cancer · January 2015 BackgroundThe health benefits of diet and exercise interventions for cancer survivors are well documented. However, little is known regarding demographic and medical predictors of survivors' willingness to participate in diet and exercise interven ... Full text Cite

Diet and exercise intervention adherence and health-related outcomes among older long-term breast, prostate, and colorectal cancer survivors.

Journal Article Ann Behav Med · October 2014 BACKGROUND: Diet and exercise interventions for cancer survivors result in health benefits; however, few studies have examined health outcomes in relation to adherence. PURPOSE: We examined associations between adherence to components of a diet-exercise in ... Full text Link to item Cite

Daughters and Mothers Against Breast Cancer (DAMES): main outcomes of a randomized controlled trial of weight loss in overweight mothers with breast cancer and their overweight daughters.

Journal Article Cancer · August 15, 2014 BACKGROUND: Few studies to date have used the cancer diagnosis as a teachable moment to promote healthy behavior changes in survivors of cancer and their family members. Given the role of obesity in the primary and tertiary prevention of breast cancer, the ... Full text Link to item Cite

Light-intensity activity attenuates functional decline in older cancer survivors.

Journal Article Med Sci Sports Exerc · July 2014 UNLABELLED: While moderate- to vigorous-intensity physical activities (MVPA) confer the greatest health benefits, evidence suggests that light-intensity activities are also beneficial, particularly for older adults and individuals with moderate to severe c ... Full text Link to item Cite

Utilization of the EPIC electronic health record system for clinical trials management at duke university

Conference Proceedings 2014 IEEE International Conference on Healthcare Informatics Ichi 2014 · March 2, 2014 Academic Medical Centers continually struggle with clinical trials study management. A common approach is the implementation of a Clinical Trials Management System. However, integration of the Clinical Trials Management System with the health system's Elec ... Full text Cite

Accuracy of 30-day recall for components of sexual function and the moderating effects of gender and mood.

Journal Article J Sex Med · March 2014 INTRODUCTION: Despite the ubiquity of 1-month recall periods for measures of sexual function, there is limited evidence for how well recalled responses correspond to individuals' actual daily experiences. AIM: To characterize the correspondence between dai ... Full text Link to item Cite

Cancer-specific concerns and physical activity among recently diagnosed breast and prostate cancer survivors.

Journal Article Integr Cancer Ther · May 2013 BACKGROUND: Cancer treatment -related side effects may have a negative impact on quality of life among cancer survivors and may limit participation in physical activity (PA). HYPOTHESIS: Cancer-specific concerns will be reduced throughout a 10-month diet a ... Full text Link to item Cite

Long-term outcomes of the FRESH START trial: exploring the role of self-efficacy in cancer survivors' maintenance of dietary practices and physical activity.

Journal Article Psychooncology · April 2013 BACKGROUND: This study examined whether changes in self-efficacy explain the effects of a mailed print intervention on long-term dietary practices of breast and prostate cancer survivors. The relationship between change in self-efficacy and long-term physi ... Full text Link to item Cite

Flaxseed-derived enterolactone is inversely associated with tumor cell proliferation in men with localized prostate cancer.

Journal Article J Med Food · April 2013 Enterolactone and enterodiol, mammalian lignans derived from dietary sources such as flaxseed, sesame seeds, kale, broccoli, and apricots, may impede tumor proliferation by inhibiting activation of nuclear factor kappa B (NFκB) and vascular endothelial gro ... Full text Link to item Cite

Research management team (RMT): a model for research support services at Duke University.

Journal Article Clin Transl Sci · December 2012 Collecting and managing data for clinical and translational research presents significant challenges for clinical and translational researchers, many of whom lack needed access to data management expertise, methods, and tools. At many institutions, funding ... Full text Link to item Cite

Phytochemicals and cancer risk: a review of the epidemiological evidence.

Journal Article Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · October 2012 A number of epidemiological studies have investigated associations between various phytochemicals and cancer risk. Phytoestrogens and carotenoids are the two most commonly studied classes of phytochemicals; phytosterols, isothiocyanates, and chlorophyll al ... Full text Cite

Long-term physical activity outcomes of home-based lifestyle interventions among breast and prostate cancer survivors.

Journal Article Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · October 2012 PurposeFew studies have investigated long-term effects of physical activity (PA) interventions. The goal of this study was to evaluate whether or not increased levels of moderate to vigorous physical activity (MVPA) were maintained by cancer survi ... Full text Cite

Evaluation of partial and total splenectomy in children with sickle cell disease using an Internet-based registry.

Journal Article Pediatr Blood Cancer · July 15, 2012 BACKGROUND: Clinical outcomes of children with sickle cell disease (SCD) who undergo total or partial splenectomy (PS) are poorly defined. The purpose of this retrospective study was to initiate an Internet-based registry to facilitate analysis of clinical ... Full text Link to item Cite

Reach out to enhance wellness home-based diet-exercise intervention promotes reproducible and sustainable long-term improvements in health behaviors, body weight, and physical functioning in older, overweight/obese cancer survivors.

Journal Article J Clin Oncol · July 1, 2012 PURPOSE: Diet and exercise interventions have been tested in cancer survivors as a means to reduce late effects and comorbidity, but few have assessed adherence and health outcomes long term. METHODS: Between July 2005 and May 2007, the Reach Out to Enhanc ... Full text Link to item Cite

Dietary patterns differ between urban and rural older, long-term survivors of breast, prostate, and colorectal cancer and are associated with body mass index.

Journal Article J Acad Nutr Diet · June 2012 BACKGROUND: Older adult cancer survivors are at greater risk of cancer recurrence and other comorbidities that can be prevented through improved diet and weight management. The tertiary prevention needs of rural-dwelling survivors can be even greater, yet ... Full text Link to item Cite

Extant health behaviors and uptake of standardized vs tailored health messages among cancer survivors enrolled in the FRESH START trial: a comparison of fighting-spirits vs fatalists.

Journal Article Psychooncology · January 2012 OBJECTIVE: Cancer coping styles have been associated with several cancer-related outcomes. We examined whether baseline lifestyle behaviors differed between cancer survivors with fatalistic vs fighting-spirit coping styles, and whether there was differenti ... Full text Link to item Cite

Prostatic alpha-linolenic acid (ALA) is positively associated with aggressive prostate cancer: a relationship which may depend on genetic variation in ALA metabolism.

Journal Article PLoS One · 2012 Previous observational studies have reported associations between prostate cancer and alpha-linolenic acid (ALA). However, few investigations have been able to study this relationship prospectively and in well-controlled settings. Moreover, no studies have ... Full text Open Access Link to item Cite

Exercise among breast and prostate cancer survivors--what are their barriers?

Journal Article J Cancer Surviv · December 2011 INTRODUCTION: Despite proven benefits of regular physical activity, estimates indicate that few cancer survivors meet physical activity guidelines. The purpose of this paper is to identify and compare exercise barriers among cancer survivors, both cross-se ... Full text Link to item Cite

Long-term dietary outcomes of the FRESH START intervention for breast and prostate cancer survivors.

Journal Article J Am Diet Assoc · December 2011 BACKGROUND: Cancer survivors are at increased risk for secondary cancers and other diseases. Healthy dietary practices may improve cancer survivors' health and well-being. OBJECTIVE: The durability of the effects of the FRESH START intervention, a program ... Full text Link to item Cite

Effect of low-fat diets on plasma levels of NF-κB-regulated inflammatory cytokines and angiogenic factors in men with prostate cancer.

Journal Article Cancer Prev Res (Phila) · October 2011 Diet, nutritional status, and certain dietary supplements are postulated to influence the development and progression of prostate cancer. Angiogenesis and inflammation are central to tumor growth and progression, but the effect of diet on these processes r ... Full text Link to item Cite

Promoting healthy lifestyles in older cancer survivors to improve health and preserve function.

Journal Article J Am Geriatr Soc · November 2009 Currently, there are about 7 million cancer survivors in this country aged 65 and older, and this number is expected to increase rapidly, given trends toward aging and improvements in early detection and treatment. Unfortunately, cancer survivors are at ri ... Full text Link to item Cite

Associations between lifestyle factors and quality of life among older long-term breast, prostate, and colorectal cancer survivors.

Journal Article Cancer · September 1, 2009 BACKGROUND: Older cancer survivors are at increased risk for secondary cancers, cardiovascular disease, obesity, and functional decline and, thus, may benefit from health-related interventions. However, to the authors' knowledge, little is known regarding ... Full text Link to item Cite

Comparing the 7-day physical activity recall with a triaxial accelerometer for measuring time in exercise.

Journal Article Med Sci Sports Exerc · June 2009 PURPOSE: The primary study aim was to evaluate associations of estimated weekly minutes of moderate-to-vigorous-intensity exercise from self-reports of the telephone-administered 7-Day Physical Activity Recall (7-Day PAR) with data captured by the RT3 tria ... Full text Link to item Cite

Effects of home-based diet and exercise on functional outcomes among older, overweight long-term cancer survivors: RENEW: a randomized controlled trial.

Journal Article JAMA · May 13, 2009 CONTEXT: Five-year survival rates for early stage colorectal, breast, and prostate cancer currently exceed 90% and are increasing. Cancer survivors are at greater risk for second malignancies, other comorbidities, and accelerated functional decline. Lifest ... Full text Link to item Cite

Reach out to ENhancE Wellness in Older Cancer Survivors (RENEW): design, methods and recruitment challenges of a home-based exercise and diet intervention to improve physical function among long-term survivors of breast, prostate, and colorectal cancer.

Journal Article Psychooncology · April 2009 OBJECTIVE: Cure rates for cancer are increasing, especially for breast, prostate, and colorectal cancer. Despite positive trends in survivorship, a cancer diagnosis can trigger accelerated functional decline that can threaten independence, reduce quality-o ... Full text Link to item Cite

Flaxseed supplementation (not dietary fat restriction) reduces prostate cancer proliferation rates in men presurgery.

Journal Article Cancer Epidemiol Biomarkers Prev · December 2008 BACKGROUND: Prostate cancer affects one of six men during their lifetime. Dietary factors are postulated to influence the development and progression of prostate cancer. Low-fat diets and flaxseed supplementation may offer potentially protective strategies ... Full text Link to item Cite

Dietary counseling and quality of life.

Journal Article The journal of supportive oncology · November 2008 Cite

Cancer survivors' health worries and associations with lifestyle practices.

Journal Article J Health Psychol · November 2008 This study examined among recently diagnosed breast and prostate cancer survivors (N = 678) associations between worry about a future diagnosis of heart disease or cancer and hypothetical and actual adherence to exercise and dietary guidelines. Greater wor ... Full text Link to item Cite

Change in self-efficacy partially mediates the effects of the FRESH START intervention on cancer survivors' dietary outcomes.

Journal Article Psychooncology · October 2008 OBJECTIVE: This study examined change in self-efficacy as a mediator of the effects of a mailed print intervention on the dietary and exercise practices of newly diagnosed breast and prostate cancer survivors. METHOD: A total of 543 breast and prostate can ... Full text Link to item Cite

Effect of physical activity guidelines on physical function in older adults.

Journal Article J Am Geriatr Soc · October 2008 OBJECTIVES: To determine whether elderly people who meet national guidelines have higher physical function (PF) scores than those who do not and the effect on functional trajectory when physical activity (PA) levels change from above to below this threshol ... Full text Link to item Cite

Dietary supplement use among elderly, long-term cancer survivors.

Journal Article J Cancer Surviv · September 2008 INTRODUCTION: The purpose of the present study was to assess dietary supplement use and its association with micronutrient intakes and diet quality among older (>or=65 years), long-term survivors (>or=5 years post-diagnosis) of female breast, prostate, and ... Full text Link to item Cite

Differences in baseline characteristics and outcomes at 1- and 2-year follow-up of cancer survivors accrued via self-referral versus cancer registry in the FRESH START Diet and exercise trial.

Journal Article Cancer Epidemiol Biomarkers Prev · May 2008 Participant accrual to research studies is a challenge; oftentimes, advertisements are used to supplement cases ascertained through clinic caseloads and cancer registries. It is unknown, however, if cases ascertained through these two sources differ. In th ... Full text Link to item Cite

Results of a diet/exercise feasibility trial to prevent adverse body composition change in breast cancer patients on adjuvant chemotherapy.

Journal Article Clin Breast Cancer · February 2008 PURPOSE: Patients with breast cancer on adjuvant chemotherapy can experience weight gain and concurrent losses in muscle mass. Exercise interventions can prevent these changes, but time and travel pose barriers to participation. The Survivor Training for E ... Full text Link to item Cite

Overcoming challenges in designing and implementing a phase II randomized controlled trial using a presurgical model to test a dietary intervention in prostate cancer.

Journal Article Clin Trials · 2008 BACKGROUND: The time between the diagnosis of cancer and a planned definitive surgical procedure offers a strong and direct approach for assessing the impact of interventions (including lifestyle interventions) on the biology of the target tissue and the t ... Full text Link to item Cite

Childhood cancer survivors' perceived barriers to improving exercise and dietary behaviors.

Journal Article Oncol Nurs Forum · January 2008 PURPOSE/OBJECTIVES: To determine childhood cancer survivors' barriers to increasing exercise and consuming less fat and more fruits and vegetables, whole grains, and calcium-rich foods. DESIGN: Mailed survey. SETTING: Cases from a comprehensive cancer cent ... Full text Link to item Cite

Main outcomes of the FRESH START trial: a sequentially tailored, diet and exercise mailed print intervention among breast and prostate cancer survivors.

Journal Article J Clin Oncol · July 1, 2007 PURPOSE: Cancer survivors are at increased risk for cardiovascular disease, diabetes, osteoporosis, and second primary tumors. Healthful lifestyle practices may improve the health and well-being of survivors. The FRESH START trial tested the efficacy of se ... Full text Link to item Cite

The Effect of Flaxseed Supplementation on Hormonal Levels Associated with Polycystic Ovarian Syndrome: A Case Study.

Journal Article Curr Top Nutraceutical Res · 2007 Flaxseed is a rich source of lignan and has been shown to reduce androgen levels in men with prostate cancer. Polycystic ovarian syndrome (PCOS), a common endocrine disorder among women in their reproductive years, also is associated with high levels of an ... Link to item Cite

Lifestyle interventions in cancer survivors: designing programs that meet the needs of this vulnerable and growing population.

Journal Article The Journal of nutrition · January 2007 In the world today, there are roughly 25 million cancer survivors. Although the increasing numbers of survivors testifies to the success of early detection and treatment, there is a downside. Cancer survivors are at increased risk for second cancers, other ... Full text Cite

Lifestyle intervention development study to improve physical function in older adults with cancer: outcomes from Project LEAD.

Journal Article J Clin Oncol · July 20, 2006 PURPOSE: Declines in physical functioning (PF) among elderly cancer patients threaten quality of life and the ability to maintain independence. Adherence to healthy lifestyle behaviors may prevent functional decline. PATIENTS AND METHODS: Project Leading t ... Full text Link to item Cite

The teachable moment following cancer diagnosis: the FRESH START trial.

Journal Article American Journal of Oncology Review · January 2006 no abstract available ... Cite

A simple, flexible and scalable approach for generating tailored questionnaires and health education messages.

Journal Article Comput Inform Nurs · 2005 Tailored health information is important for generating patient-specific recommendations in clinical decision support systems and for crafting health education materials that are specifically customized to a patient. Many previous attempts to generate tail ... Full text Link to item Cite

Physical function and associations with diet and exercise: Results of a cross-sectional survey among elders with breast or prostate cancer.

Journal Article Int J Behav Nutr Phys Act · October 29, 2004 BACKGROUND: Functional decline threatens independent living and is common among individuals diagnosed with cancer, especially those who are elderly. The purpose of this study was to explore whether dietary and exercise practices are associated with physica ... Full text Open Access Link to item Cite

Agreement between a brief mailed screener and an in-depth telephone survey: observations from the Fresh Start study.

Journal Article J Am Diet Assoc · October 2004 Brief screening instruments can roughly characterize individual behavior and target those most in need of change. However, the level of agreement between abbreviated and full-scale instruments is often unknown. We determined agreement between a brief scree ... Full text Link to item Cite

Leading the Way in Exercise and Diet (Project LEAD): intervening to improve function among older breast and prostate cancer survivors.

Journal Article Control Clin Trials · April 2003 The U.S. population is aging, bringing with it an increased prevalence of chronic disease and concomitant declines in physical function. The risk of developing cancer increases significantly with age, and functional decline is much more likely once a cance ... Full text Link to item Cite

Design of FRESH START: a randomized trial of exercise and diet among cancer survivors.

Journal Article Med Sci Sports Exerc · March 2003 PURPOSE: FRESH START is a randomized controlled trial that will test whether a personally tailored, distance-medicine-based program will increase exercise and fruit and vegetable consumption, and decrease fat intake of individuals recently diagnosed with b ... Full text Link to item Cite